Howard Gardner's multiple intelligences theory, outcomes-based education and curriculum implementation in South Africa : a critique of music education in the general education and training phase
- Authors: Clench, Renate
- Date: 2010
- Subjects: Music -- Instruction and study -- South Africa , School music -- Instruction and study -- South africa , Music in education , Intellect
- Language: English
- Type: Thesis , Masters , MMus
- Identifier: vital:8507 , http://hdl.handle.net/10948/1218 , Music -- Instruction and study -- South Africa , School music -- Instruction and study -- South africa , Music in education , Intellect
- Description: This study examines the current curriculum for primary schools in South Africa – Curriculum 2005 (C2005) and the subsequent Revised National Curriculum Statement (RNCS), with Outcomes-Based Education (OBE) as its fundamental educational approach - with specific reference to the place of music education in it. While the underlying principles and scope of this curriculum has many positive attributes, numerous studies have shown that there are still major stumbling blocks in the way of its successful implementation. Since the emphasis of the Arts and Culture Learning Area is on the nurturing of generic values and attitudes towards culture, it does not provide for sufficient development of subject-specific musical skills and knowledge. Instead this vital form of musical learning continues to be provided in the form of extra-curricular music programmes by those few schools who have the staff expertise and the funding to do so. Music therefore remains accessible only to the privileged few. .Although C2005 encourages and requires significant levels of integration in Learning Outcomes and Assessment Standards within and across Learning Areas, this is currently one of the least successful aspects of its implementation. This lack of success, it is argued, is in part the result of severe limitations in the training of teachers and the availability of necessary resources in schools, and in part the result of the curriculum’s own limited interpretation of integration. Psychologist Dr Howard Gardner’s Theory of Multiple Intelligences is a holistic approach to education that stresses, amongst other things, that Musical Intelligence is one of eight vital forms of intelligence that should be accessible to all children. It is argued that educational approaches based on Gardner’s Multiple Intelligences Theory provide some insights into the integration of Musical Intelligence with other forms of learning that may usefully be applied in C2005.
- Full Text:
- Date Issued: 2010
- Authors: Clench, Renate
- Date: 2010
- Subjects: Music -- Instruction and study -- South Africa , School music -- Instruction and study -- South africa , Music in education , Intellect
- Language: English
- Type: Thesis , Masters , MMus
- Identifier: vital:8507 , http://hdl.handle.net/10948/1218 , Music -- Instruction and study -- South Africa , School music -- Instruction and study -- South africa , Music in education , Intellect
- Description: This study examines the current curriculum for primary schools in South Africa – Curriculum 2005 (C2005) and the subsequent Revised National Curriculum Statement (RNCS), with Outcomes-Based Education (OBE) as its fundamental educational approach - with specific reference to the place of music education in it. While the underlying principles and scope of this curriculum has many positive attributes, numerous studies have shown that there are still major stumbling blocks in the way of its successful implementation. Since the emphasis of the Arts and Culture Learning Area is on the nurturing of generic values and attitudes towards culture, it does not provide for sufficient development of subject-specific musical skills and knowledge. Instead this vital form of musical learning continues to be provided in the form of extra-curricular music programmes by those few schools who have the staff expertise and the funding to do so. Music therefore remains accessible only to the privileged few. .Although C2005 encourages and requires significant levels of integration in Learning Outcomes and Assessment Standards within and across Learning Areas, this is currently one of the least successful aspects of its implementation. This lack of success, it is argued, is in part the result of severe limitations in the training of teachers and the availability of necessary resources in schools, and in part the result of the curriculum’s own limited interpretation of integration. Psychologist Dr Howard Gardner’s Theory of Multiple Intelligences is a holistic approach to education that stresses, amongst other things, that Musical Intelligence is one of eight vital forms of intelligence that should be accessible to all children. It is argued that educational approaches based on Gardner’s Multiple Intelligences Theory provide some insights into the integration of Musical Intelligence with other forms of learning that may usefully be applied in C2005.
- Full Text:
- Date Issued: 2010
Identifying, recording and monitoring adverse effects associated with antriretroviral treatment
- Authors: Mulinge, Florence Muthoni
- Date: 2010
- Subjects: Highly active antiretroviral therapy , Antiretroviral agents -- South Africa -- Uitenhage , HIV infections -- Treatment -- South Africa -- Uitenhage , AIDS (Disease) -- Treatment -- South Africa -- Uitenhage
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:10131 , http://hdl.handle.net/10948/1491 , Highly active antiretroviral therapy , Antiretroviral agents -- South Africa -- Uitenhage , HIV infections -- Treatment -- South Africa -- Uitenhage , AIDS (Disease) -- Treatment -- South Africa -- Uitenhage
- Description: South Africa, with an estimated 5.7 million people living with HIV, continues to have one of the largest epidemics in the world. The introduction of HAART resulted in prolonged and improved quality of life of many infected patients. However, adverse effects caused by these drugs have become a major concern as they affect the adherence of patients and in some cases even result in the death of patients. Although much research has been and is still being conducted in the area of understanding, preventing and management of ARV adverse effects, there is still a need for patients to be actively involved in self-monitoring for adverse effects. This will assist health care professionals in early identification of serious or potentially serious ARV effects. This study aimed at evaluating the usefulness of strategies developed and employed in the identification, recording and monitoring of adverse effects. The study was conducted with patients receiving HAART from a private HIV and AIDS clinic in Uitenhage, Eastern Cape, South Africa. The research project was approved by the Nelson Mandela Metropolitan University Research and Ethics Committee and the research site. This was an experimental, randomized controlled study carried out over a period of three months (August to October 2009), with a sample size of 160 patients divided into four study groups of 40 patients each. Two monitoring strategies, namely an ARV adverse effect monitoring tool and a patient self-monitoring diary were developed and used for the identification and recording of adverse effects. The four study groups included a Control group, a Tool group, a Diary group and a Tool-Diary group. Willing patients, after signing an informed consent form, were randomly assigned to one of the four groups by participating health care workers at the study site. Data was retrieved from the patient files by the researcher. Descriptive statistical analysis of the findings of the study was conducted using SPSS®. One hundred and forty nine patients were included in the final data analysis. Of the 80 diaries handed out to patients, only 33 were returned and due to errors only 31 were suitable for analysis. Monitoring tools were completed and analysed for 36 patients. The tool was found to be more effective in identifying adverse effects of a physical nature (such as peripheral neuropathy and lipodystrophy) than the usual methods of monitoring employed by the clinic, whilst the diary, used alone, was found to be less effective. Use of the tool and diary combined resulted in the most significant identification and recording of central nervous system related adverse effects and physical adverse effects. However due to the low return rate of the diaries and the majority of the monitoring tool not being completed in many instances the results of this study may not be generalisable. The study results did however suggest that combining the tool and the diary methods of adverse effect identification, yielded the most favourable results when compared to each method alone. This may be attributed to the fact that the tool is useful in identifying objective symptoms and the diaries subjective symptoms, particularly in instances where the patients forget to report their symptoms to healthcare professional whilst at the clinic. The diaries were also reported to improve adherence for more than 90 percentage (n=31) of the patients. More research would be needed in order to verify the exact significance of the tool and the diary in identifying and recording adverse effects and symptoms of adverse effects.
- Full Text:
- Date Issued: 2010
- Authors: Mulinge, Florence Muthoni
- Date: 2010
- Subjects: Highly active antiretroviral therapy , Antiretroviral agents -- South Africa -- Uitenhage , HIV infections -- Treatment -- South Africa -- Uitenhage , AIDS (Disease) -- Treatment -- South Africa -- Uitenhage
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:10131 , http://hdl.handle.net/10948/1491 , Highly active antiretroviral therapy , Antiretroviral agents -- South Africa -- Uitenhage , HIV infections -- Treatment -- South Africa -- Uitenhage , AIDS (Disease) -- Treatment -- South Africa -- Uitenhage
- Description: South Africa, with an estimated 5.7 million people living with HIV, continues to have one of the largest epidemics in the world. The introduction of HAART resulted in prolonged and improved quality of life of many infected patients. However, adverse effects caused by these drugs have become a major concern as they affect the adherence of patients and in some cases even result in the death of patients. Although much research has been and is still being conducted in the area of understanding, preventing and management of ARV adverse effects, there is still a need for patients to be actively involved in self-monitoring for adverse effects. This will assist health care professionals in early identification of serious or potentially serious ARV effects. This study aimed at evaluating the usefulness of strategies developed and employed in the identification, recording and monitoring of adverse effects. The study was conducted with patients receiving HAART from a private HIV and AIDS clinic in Uitenhage, Eastern Cape, South Africa. The research project was approved by the Nelson Mandela Metropolitan University Research and Ethics Committee and the research site. This was an experimental, randomized controlled study carried out over a period of three months (August to October 2009), with a sample size of 160 patients divided into four study groups of 40 patients each. Two monitoring strategies, namely an ARV adverse effect monitoring tool and a patient self-monitoring diary were developed and used for the identification and recording of adverse effects. The four study groups included a Control group, a Tool group, a Diary group and a Tool-Diary group. Willing patients, after signing an informed consent form, were randomly assigned to one of the four groups by participating health care workers at the study site. Data was retrieved from the patient files by the researcher. Descriptive statistical analysis of the findings of the study was conducted using SPSS®. One hundred and forty nine patients were included in the final data analysis. Of the 80 diaries handed out to patients, only 33 were returned and due to errors only 31 were suitable for analysis. Monitoring tools were completed and analysed for 36 patients. The tool was found to be more effective in identifying adverse effects of a physical nature (such as peripheral neuropathy and lipodystrophy) than the usual methods of monitoring employed by the clinic, whilst the diary, used alone, was found to be less effective. Use of the tool and diary combined resulted in the most significant identification and recording of central nervous system related adverse effects and physical adverse effects. However due to the low return rate of the diaries and the majority of the monitoring tool not being completed in many instances the results of this study may not be generalisable. The study results did however suggest that combining the tool and the diary methods of adverse effect identification, yielded the most favourable results when compared to each method alone. This may be attributed to the fact that the tool is useful in identifying objective symptoms and the diaries subjective symptoms, particularly in instances where the patients forget to report their symptoms to healthcare professional whilst at the clinic. The diaries were also reported to improve adherence for more than 90 percentage (n=31) of the patients. More research would be needed in order to verify the exact significance of the tool and the diary in identifying and recording adverse effects and symptoms of adverse effects.
- Full Text:
- Date Issued: 2010
Impact assessment of local economic development in the Amathole district municipality with special reference to agriculture
- Authors: Mpengu, Mbuyiseli
- Date: 2010
- Subjects: Sustainable development -- South Africa -- Eastern Cape , Agriculture and state -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:8203 , http://hdl.handle.net/10948/1198 , Sustainable development -- South Africa -- Eastern Cape , Agriculture and state -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape
- Description: In this study, Local Economic Development (LED) is defined as an outcome of processes aimed at building up the capacity of local areas for sustainable economic development. The study assesses whether LED interventions, especially agricultural programmes, improve the livelihoods of poor communities in the Amathole District Municipality. Data was collected by use of both qualitative and quantitative research methods through interviews and questionnaires, respectively. Probability and non-probability sampling techniques were used to identify the research sample from the target population. These were further broken down into stratified, purposive and snowball sampling to enable the researcher to select specific municipalities, councillors, officials and stakeholders who participated in the study. Budgetary constraints, staff shortages and lack of required skills/ expertise were identified as the main challenges facing the district. The latter makes it difficult for the municipality to effectively implement sound LED programmes. Consequently, LED benefits are minimal. It is, therefore, recommendable for the municipality to seek other means of generating and boosting their financial viability through partnerships and private sector investments. This in turn will generate revenue for the municipality and ensure economic development in the district, thereby making a meaningful contribution towards the realization of a goal for “a better life for all”.
- Full Text:
- Date Issued: 2010
- Authors: Mpengu, Mbuyiseli
- Date: 2010
- Subjects: Sustainable development -- South Africa -- Eastern Cape , Agriculture and state -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:8203 , http://hdl.handle.net/10948/1198 , Sustainable development -- South Africa -- Eastern Cape , Agriculture and state -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape
- Description: In this study, Local Economic Development (LED) is defined as an outcome of processes aimed at building up the capacity of local areas for sustainable economic development. The study assesses whether LED interventions, especially agricultural programmes, improve the livelihoods of poor communities in the Amathole District Municipality. Data was collected by use of both qualitative and quantitative research methods through interviews and questionnaires, respectively. Probability and non-probability sampling techniques were used to identify the research sample from the target population. These were further broken down into stratified, purposive and snowball sampling to enable the researcher to select specific municipalities, councillors, officials and stakeholders who participated in the study. Budgetary constraints, staff shortages and lack of required skills/ expertise were identified as the main challenges facing the district. The latter makes it difficult for the municipality to effectively implement sound LED programmes. Consequently, LED benefits are minimal. It is, therefore, recommendable for the municipality to seek other means of generating and boosting their financial viability through partnerships and private sector investments. This in turn will generate revenue for the municipality and ensure economic development in the district, thereby making a meaningful contribution towards the realization of a goal for “a better life for all”.
- Full Text:
- Date Issued: 2010
Impact pf provincial local government support for effective implementation of PMS in municipalities (Lukhanji municipality)
- Sidinana, Ngenanimazizi Orsmond
- Authors: Sidinana, Ngenanimazizi Orsmond
- Date: 2010
- Subjects: Benchmarking (Management) , Local government
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9159 , http://hdl.handle.net/10948/d1020000
- Description: One of the more frequently heard criticisms of local government is that it is not delivering the required services or it is not delivering an efficient standard of service. Performance management for local government contributes to creating a performance culture in the public service at municipal level. Performance management is a mechanism that is used to ensure that the municipality is doing its work and delivering on its mandate. The SALGA HRD Policy Conference held in March 2003 endorsed the spirit of the relevant legislation on performance management in municipalities. As the employee body and the only recognized voice of municipalities in the country, SALGA has been of the view that the legislative imperative placed on municipalities to be developmental and performance orientated cannot be overly emphasized. Concomitant with the legislative imperative has been the political will or unwavering political commitment to ensure that municipal administrations are accountable to their respective councils, and by extension, the communities they serve. The successful implementation of the Performance Management System at all municipalities will certainly serve as a yardstick in objectively measuring the performance of municipal and provincial local government officials. It is believed that the ongoing measurement of performance will inevitably lead to better delivery of services to our people. The Constitution of South Africa places a developmental mandate on local governments, with the express purpose of them providing effective and efficient services to their communities and to promote local social and economic development. Further to this, the Municipal Systems Act of 2000 provides a legislative framework for municipalities to embark on integrated development planning. Thus all municipalities require an Integrated Development Plan (lDP) to be in place in order to fully realize their objectives as set out in Section 152 of the Constitution. In the interpretation of the legislation, it is clear that the Council (the political body of the municipality) is held responsible to ensure that its municipality has an lDP and PMS in place. Thus both the political principal and the leadership of a municipality are, by law, required to fulfil their obligations in implementing the PMS, while the provincial local government department is charged with the obligation to ensure that such objectives by municipalities are realized by way of providing financial and human capital assistance. Since the lDP and PMS have been legislated in such a manner, it thus becomes legally imperative that municipalities comply with the legislation. The Auditor General is thus required to audit a municipality within this context. Failure to comply may entail certain legal repercussions. Generally, there has been a drive to inculcate improved performance in all three spheres of government. However, it becomes integral that municipalities are performance oriented, especially since it is the sphere of government closest to the grass-roots levels where the real impact of service delivery is experienced. There is undoubtedly a link between lDP and PM. However, it has been observed that both in municipalities and provincial local government there is no synergy between these two components and they tend to operate in isolation of each other. Logically, the scorecards of the organisation and individuals should be derived from the municipality's IDP; however this is not always the case. It is also evident that both the municipality and provincial local government approaches the two issues as different disciplines. Having said this, it is important for SALGA and Provincial Local Government to encourage and ensure better alignment of lDP and PMS in both the province and municipalities.
- Full Text:
- Date Issued: 2010
- Authors: Sidinana, Ngenanimazizi Orsmond
- Date: 2010
- Subjects: Benchmarking (Management) , Local government
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9159 , http://hdl.handle.net/10948/d1020000
- Description: One of the more frequently heard criticisms of local government is that it is not delivering the required services or it is not delivering an efficient standard of service. Performance management for local government contributes to creating a performance culture in the public service at municipal level. Performance management is a mechanism that is used to ensure that the municipality is doing its work and delivering on its mandate. The SALGA HRD Policy Conference held in March 2003 endorsed the spirit of the relevant legislation on performance management in municipalities. As the employee body and the only recognized voice of municipalities in the country, SALGA has been of the view that the legislative imperative placed on municipalities to be developmental and performance orientated cannot be overly emphasized. Concomitant with the legislative imperative has been the political will or unwavering political commitment to ensure that municipal administrations are accountable to their respective councils, and by extension, the communities they serve. The successful implementation of the Performance Management System at all municipalities will certainly serve as a yardstick in objectively measuring the performance of municipal and provincial local government officials. It is believed that the ongoing measurement of performance will inevitably lead to better delivery of services to our people. The Constitution of South Africa places a developmental mandate on local governments, with the express purpose of them providing effective and efficient services to their communities and to promote local social and economic development. Further to this, the Municipal Systems Act of 2000 provides a legislative framework for municipalities to embark on integrated development planning. Thus all municipalities require an Integrated Development Plan (lDP) to be in place in order to fully realize their objectives as set out in Section 152 of the Constitution. In the interpretation of the legislation, it is clear that the Council (the political body of the municipality) is held responsible to ensure that its municipality has an lDP and PMS in place. Thus both the political principal and the leadership of a municipality are, by law, required to fulfil their obligations in implementing the PMS, while the provincial local government department is charged with the obligation to ensure that such objectives by municipalities are realized by way of providing financial and human capital assistance. Since the lDP and PMS have been legislated in such a manner, it thus becomes legally imperative that municipalities comply with the legislation. The Auditor General is thus required to audit a municipality within this context. Failure to comply may entail certain legal repercussions. Generally, there has been a drive to inculcate improved performance in all three spheres of government. However, it becomes integral that municipalities are performance oriented, especially since it is the sphere of government closest to the grass-roots levels where the real impact of service delivery is experienced. There is undoubtedly a link between lDP and PM. However, it has been observed that both in municipalities and provincial local government there is no synergy between these two components and they tend to operate in isolation of each other. Logically, the scorecards of the organisation and individuals should be derived from the municipality's IDP; however this is not always the case. It is also evident that both the municipality and provincial local government approaches the two issues as different disciplines. Having said this, it is important for SALGA and Provincial Local Government to encourage and ensure better alignment of lDP and PMS in both the province and municipalities.
- Full Text:
- Date Issued: 2010
Implementation of intravenous to oral antibiotic switch therapy guidelines in the general medical wards of a tertiary level hospital
- Authors: Van Niekerk, Anida
- Date: 2010
- Subjects: Antibiotics -- Administration
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:10160 , http://hdl.handle.net/10948/1325 , http://hdl.handle.net/10948/d1012901 , Antibiotics -- Administration
- Description: The overuse of antibiotics and consequent resistance is a common problem in medical practice worldwide. Switch therapy is a technique that can be applied to streamline antibiotic therapy reducing unnecessary prolonged Intravenous (IV) antibiotic therapy. Antibiotic switch therapy has several other benefits such as: decreasing length of hospital stay; decreasing the incidence of adverse events associated with the administration of IV antibiotics; decreasing direct and indirect hospitalisation costs while improving patients’ comfort and mobility; and decreasing the risk of acquiring nosocomial infections. Certain elements are required to make the implementation of any guideline, including a switch therapy guideline, a success and probably one of the most important is the support from a motivated multidisciplinary team. The role of such a team, in the South African context, would be filled by the Pharmacy and Therapeutics Committee (PTC). In addition, to make a guideline successful it should be continuously implemented. This responsibility traditionally falls to a pharmacist. In the United Kingdom (UK) and the United States of America (USA) pharmacists are used to promote the appropriate use of antibiotics in hospitals as this has shown to have several economic advantages. The objectives of the study were: to determine, by means of a survey, whether guidelines for IV to oral switch were employed in South African regional, tertiary and national government hospitals; to design and implement an IV to oral antibiotic switch therapy (IVOST) guideline for a local public sector tertiary level hospital; to evaluate the effectiveness of guideline implementation; and to capture, via a questionnaire, the perceptions of prescribers regarding antibiotic prescribing, including switch therapy. The Survey of Current IV Switch Therapy Practice Questionnaire was distributed to Responsible Pharmacists at regional, provincial tertiary and national central government hospitals to determine whether IVOST guidelines were employed in South African government hospitals. Following the survey, an IVOST Guideline was designed by the researcher in consultation with the Department of Medicine and the Department of Pharmacy. The IVOST Guideline was implemented following approval by the PTC at a local tertiary level government hospital. A presentation was held for prescribers, guideline documents were distributed, posters were placed in the medical wards and the ward pharmacist/researcher integrated the guideline into daily practice by placing “reminder stickers” in patient medical folders. A pre-implementation audit and two post-implementation audits, each consisting of 150 patient medical records, were conducted and compared to determine the effect of IVOST guideline implementation on prescribing patterns and to determine whether any changes could be sustained. The Prescriber Antibiotic Survey was then conducted to capture the perceptions of prescribers regarding antibiotic therapy, including switch therapy.
- Full Text:
- Date Issued: 2010
- Authors: Van Niekerk, Anida
- Date: 2010
- Subjects: Antibiotics -- Administration
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:10160 , http://hdl.handle.net/10948/1325 , http://hdl.handle.net/10948/d1012901 , Antibiotics -- Administration
- Description: The overuse of antibiotics and consequent resistance is a common problem in medical practice worldwide. Switch therapy is a technique that can be applied to streamline antibiotic therapy reducing unnecessary prolonged Intravenous (IV) antibiotic therapy. Antibiotic switch therapy has several other benefits such as: decreasing length of hospital stay; decreasing the incidence of adverse events associated with the administration of IV antibiotics; decreasing direct and indirect hospitalisation costs while improving patients’ comfort and mobility; and decreasing the risk of acquiring nosocomial infections. Certain elements are required to make the implementation of any guideline, including a switch therapy guideline, a success and probably one of the most important is the support from a motivated multidisciplinary team. The role of such a team, in the South African context, would be filled by the Pharmacy and Therapeutics Committee (PTC). In addition, to make a guideline successful it should be continuously implemented. This responsibility traditionally falls to a pharmacist. In the United Kingdom (UK) and the United States of America (USA) pharmacists are used to promote the appropriate use of antibiotics in hospitals as this has shown to have several economic advantages. The objectives of the study were: to determine, by means of a survey, whether guidelines for IV to oral switch were employed in South African regional, tertiary and national government hospitals; to design and implement an IV to oral antibiotic switch therapy (IVOST) guideline for a local public sector tertiary level hospital; to evaluate the effectiveness of guideline implementation; and to capture, via a questionnaire, the perceptions of prescribers regarding antibiotic prescribing, including switch therapy. The Survey of Current IV Switch Therapy Practice Questionnaire was distributed to Responsible Pharmacists at regional, provincial tertiary and national central government hospitals to determine whether IVOST guidelines were employed in South African government hospitals. Following the survey, an IVOST Guideline was designed by the researcher in consultation with the Department of Medicine and the Department of Pharmacy. The IVOST Guideline was implemented following approval by the PTC at a local tertiary level government hospital. A presentation was held for prescribers, guideline documents were distributed, posters were placed in the medical wards and the ward pharmacist/researcher integrated the guideline into daily practice by placing “reminder stickers” in patient medical folders. A pre-implementation audit and two post-implementation audits, each consisting of 150 patient medical records, were conducted and compared to determine the effect of IVOST guideline implementation on prescribing patterns and to determine whether any changes could be sustained. The Prescriber Antibiotic Survey was then conducted to capture the perceptions of prescribers regarding antibiotic therapy, including switch therapy.
- Full Text:
- Date Issued: 2010
Implementation of novel flow cytometric methods to assess the in vitro antidiabetic mechanism of a Sutherlandia Frutescens extract
- Authors: Elliot, Gayle Pamela
- Date: 2010
- Subjects: Insulin resistance -- South Africa , Insulin -- Therapeutic use -- South Africa , Medicinal plants -- South Africa , Non-insulin-dependent diabetes -- South Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:10304 , http://hdl.handle.net/10948/1439 , Insulin resistance -- South Africa , Insulin -- Therapeutic use -- South Africa , Medicinal plants -- South Africa , Non-insulin-dependent diabetes -- South Africa
- Description: The ability of insulin to stimulate glucose uptake into muscle and adipose tissue is central to the maintenance of whole-body glucose homeostasis. Deregulation of insulin action manifests itself as insulin resistance, a key component of type 2 diabetes. Insulin resistance is also observed in HIV patients receiving protease inhibitors. An agent that can reversibly induce an insulin-resistant state would be a very useful tool in developing model systems that mimic the pathogenesis of type 2 diabetes. Insulin resistance can arise from defects in insulin signal transduction, changes in the expression of proteins or genes that are targets of insulin action, cross talk from other hormonal systems or metabolic abnormalities. Deterioration of the insulin-receptor-signalling pathway at different levels leading to decreased levels of signalling pathway intermediates and/or decreased activation through phosphorylation accounts for the evolution from an insulin-resistant state to type 2 diabetes. In addition, defects in GLUT4 glucose transporter translocation are observed, further fuelling impairments in skeletal muscle glucose uptake. Levels of insulin-induced GLUT4 translocation in the skeletal muscle of type 2 diabetic patients are typically reduced by 90%. Many cellular pathways & their intermediates are in some way or another linked to insulin signalling. This study focused on three of these namely the PI3-kinase/Akt pathway, the Mitogen Activated Protein Kinase (MAPK) cascade and the AMP Kinase pathway, with successful monitoring of the PI3-K pathway. Investigations involved observing and evaluating the effects of various compounds as well as an indigenous medicinal plant, Sutherlandia frutescens on the activities of key insulin signalling pathway intermediates within the three fore mentioned pathways including Akt, AMPK and MEK1/2 as well as membrane surface GLUT4 levels. Scientific research has in the past leant heavily on Western blotting as the method of choice for gaining vital information relating to signal transduction pathways, however for research into cellular mechanisms the negatives of this method outweigh the positives. The drawbacks include a need for large amount of cells, multiple washing steps which may be disadvantageous to any weak and transient interactions as well as lysing of cells which may interfere with the maintenance of the subcellular localisation of a specific signalling event. Based on these, the need for a better method in terms of speed & reliability to monitor phosphorylation states of signal transduction pathway intermediates & GLUT4 translocation was evident and was one VII of the main aims & successes of this study. The method created used the mouse muscle cell line C2C12 in conjunction with the quick, sensitive method of flow cytometry which allowed us to monitor these processes in these cells through immune-labelling. Adherent cell cultures such as the C2C12 cell line pose the problem of possible damage to plasma membrane receptors (including insulin receptors) during harvesting to obtain a cell suspension for flow cytometry. We however used C2C12 mouse myocytes to optimize a method yielding insulin responsive cells in suspension that were successfully used for flow cytometry after immunelabelling of insulin signalling intermediates. Insulin (0.1μM) significantly raised the levels of both P-Akt and GLUT4 above basal levels. This effect was shown to be dose dependent. At a concentration of 50μg/ml, Sutherlandia frutescens was able to act as an insulin-mimetic in terms of its ability to increase P-Akt levels, GLUT4 translocation and glucose utilisation in an acute manner. These increases could be reduced with the addition of wortmannin, a PI3-K inhibitor. Therefore, these results suggest the mechanism of the plant extract’s insulin-like activity may be in part due to the activation of the insulin signalling pathway leading to GLUT4 translocation, which involves the phosphorylation of insulin receptor- and subsequent PI3-K activity, leading to P-Akt activity. These results provide further evidence of this plant extract’s anti-diabetic potential. The effect of Sutherlandia frutescens on insulin secretion, calcium signalling and proliferation in INS-1 rat pancreatic cells was also investigated and it was found to increase the activities of all of these processes. However no change in the levels of GLUT2 glucose transporter was seen. Ritonavir is prescribed by the South African Department of Health in co-formulation with other protease inhibitors within its second regime in the treatment of HIV and AIDS. Using C2C12 cells, ritonavir decreased glucose uptake acutely and had no effect on GLUT4 translocation however surprisingly increased P-Akt levels. In conclusion, it was found that Sutherlandia frutescens has antidiabetic benefits, diverse in nature depending on tissue type as well as length of time administered. The establishment of novel flow cytometry techniques to assess antidiabetic properties using in vitro cell culture was achieved. These methods will be useful in the future for the assessment of insulin sensitivity and in the identification of novel compounds that stimulate the insulin signalling pathways.
- Full Text:
- Date Issued: 2010
- Authors: Elliot, Gayle Pamela
- Date: 2010
- Subjects: Insulin resistance -- South Africa , Insulin -- Therapeutic use -- South Africa , Medicinal plants -- South Africa , Non-insulin-dependent diabetes -- South Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:10304 , http://hdl.handle.net/10948/1439 , Insulin resistance -- South Africa , Insulin -- Therapeutic use -- South Africa , Medicinal plants -- South Africa , Non-insulin-dependent diabetes -- South Africa
- Description: The ability of insulin to stimulate glucose uptake into muscle and adipose tissue is central to the maintenance of whole-body glucose homeostasis. Deregulation of insulin action manifests itself as insulin resistance, a key component of type 2 diabetes. Insulin resistance is also observed in HIV patients receiving protease inhibitors. An agent that can reversibly induce an insulin-resistant state would be a very useful tool in developing model systems that mimic the pathogenesis of type 2 diabetes. Insulin resistance can arise from defects in insulin signal transduction, changes in the expression of proteins or genes that are targets of insulin action, cross talk from other hormonal systems or metabolic abnormalities. Deterioration of the insulin-receptor-signalling pathway at different levels leading to decreased levels of signalling pathway intermediates and/or decreased activation through phosphorylation accounts for the evolution from an insulin-resistant state to type 2 diabetes. In addition, defects in GLUT4 glucose transporter translocation are observed, further fuelling impairments in skeletal muscle glucose uptake. Levels of insulin-induced GLUT4 translocation in the skeletal muscle of type 2 diabetic patients are typically reduced by 90%. Many cellular pathways & their intermediates are in some way or another linked to insulin signalling. This study focused on three of these namely the PI3-kinase/Akt pathway, the Mitogen Activated Protein Kinase (MAPK) cascade and the AMP Kinase pathway, with successful monitoring of the PI3-K pathway. Investigations involved observing and evaluating the effects of various compounds as well as an indigenous medicinal plant, Sutherlandia frutescens on the activities of key insulin signalling pathway intermediates within the three fore mentioned pathways including Akt, AMPK and MEK1/2 as well as membrane surface GLUT4 levels. Scientific research has in the past leant heavily on Western blotting as the method of choice for gaining vital information relating to signal transduction pathways, however for research into cellular mechanisms the negatives of this method outweigh the positives. The drawbacks include a need for large amount of cells, multiple washing steps which may be disadvantageous to any weak and transient interactions as well as lysing of cells which may interfere with the maintenance of the subcellular localisation of a specific signalling event. Based on these, the need for a better method in terms of speed & reliability to monitor phosphorylation states of signal transduction pathway intermediates & GLUT4 translocation was evident and was one VII of the main aims & successes of this study. The method created used the mouse muscle cell line C2C12 in conjunction with the quick, sensitive method of flow cytometry which allowed us to monitor these processes in these cells through immune-labelling. Adherent cell cultures such as the C2C12 cell line pose the problem of possible damage to plasma membrane receptors (including insulin receptors) during harvesting to obtain a cell suspension for flow cytometry. We however used C2C12 mouse myocytes to optimize a method yielding insulin responsive cells in suspension that were successfully used for flow cytometry after immunelabelling of insulin signalling intermediates. Insulin (0.1μM) significantly raised the levels of both P-Akt and GLUT4 above basal levels. This effect was shown to be dose dependent. At a concentration of 50μg/ml, Sutherlandia frutescens was able to act as an insulin-mimetic in terms of its ability to increase P-Akt levels, GLUT4 translocation and glucose utilisation in an acute manner. These increases could be reduced with the addition of wortmannin, a PI3-K inhibitor. Therefore, these results suggest the mechanism of the plant extract’s insulin-like activity may be in part due to the activation of the insulin signalling pathway leading to GLUT4 translocation, which involves the phosphorylation of insulin receptor- and subsequent PI3-K activity, leading to P-Akt activity. These results provide further evidence of this plant extract’s anti-diabetic potential. The effect of Sutherlandia frutescens on insulin secretion, calcium signalling and proliferation in INS-1 rat pancreatic cells was also investigated and it was found to increase the activities of all of these processes. However no change in the levels of GLUT2 glucose transporter was seen. Ritonavir is prescribed by the South African Department of Health in co-formulation with other protease inhibitors within its second regime in the treatment of HIV and AIDS. Using C2C12 cells, ritonavir decreased glucose uptake acutely and had no effect on GLUT4 translocation however surprisingly increased P-Akt levels. In conclusion, it was found that Sutherlandia frutescens has antidiabetic benefits, diverse in nature depending on tissue type as well as length of time administered. The establishment of novel flow cytometry techniques to assess antidiabetic properties using in vitro cell culture was achieved. These methods will be useful in the future for the assessment of insulin sensitivity and in the identification of novel compounds that stimulate the insulin signalling pathways.
- Full Text:
- Date Issued: 2010
Implementation of the dual therapy prevention of mother-to-child transmission protocol
- Authors: Singh, Vikesh
- Date: 2010
- Subjects: HIV infections -- Transmission -- South Africa , AIDS (Disease) in pregnancy -- Prevention -- South Africa , Antiretroviral agents
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:10138 , http://hdl.handle.net/10948/1374 , HIV infections -- Transmission -- South Africa , AIDS (Disease) in pregnancy -- Prevention -- South Africa , Antiretroviral agents
- Description: Antiretroviral drugs taken during pregnancy, reduce the rates of mother-to-child transmission from 35 percent to as low as 1 to 2 percent (UNAIDS, 2009). In 2002, the Prevention of Mother-to-Child Transmission (PMTCT) programme was implemented in South Africa. Studies on the implementation of the PMTCT programme have shown that understaffed and under-developed health care facilities were key barriers to the provision of PMTCT services (Health Systems Trust, 2002: 6; Skinner et al., 2003). The aim of this study was to assess the challenges experienced by health care workers working in public sector facilities in the Nelson Mandela Metropole after implementation of the dual therapy PMTCT programme. Four areas were investigated: Infrastructure; Drug Supply Management; Clinic Procedures and Staffing. A quantitative descriptive study was conducted in August 2009 at nine public health care facilities in the Nelson Mandela Metropole, South Africa. Questionnaires were issued to 81 nurses and 41 pharmacy personnel (pharmacists and pharmacist assistants). Checklist audit forms were issued to the Facility Manager of each facility and completed with the researcher. The key findings for Infrastructure were lack of space at patient waiting rooms (9; 100 percent n=9), counselling area (5; 55.5 percent; n=9), nurse consultation rooms (6; 66.6 percent; n=9), storage areas (5; 55.5 percent; n=9) and filing areas (7; 77.7 percent; n=9). The key findings for Drug Supply Management were none of the dispensaries (0 percent; n=10) were fully compliant with Good Pharmacy Practice, pharmacy personnel indicated that there were no stock cards for medication (13; 31.7 percent; n=41); there was less than two weeks supply of buffer stock kept for zidovudine and nevirapine (13; 35.1percent; n=37) and medication orders were placed without any reference to minimum and maximum levels of medication (15; 36.5 percent; n=41) . The key findings for Clinic Procedures were only two facilities followed up on patients that had missed appointments (22.2 percent; n=9) and four facilities (44.4 percent; n=9) had a tracking system for patients that had defaulted. Of the nine facilities only three (33.3 percent; n=9) updated patient demographic details regularly. The key findings for Staffing were a shortage of doctors, nurses, counsellors and pharmacists at the facilities. One of the major challenges identified was the lack of training offered on new PMTCT protocols with 56.2 percent (45; n=80) of the nurses stating that no training was provided on the dual PMTCT protocol. Only 54.3 percent (44; n=81) of nurses stated that they knew the criteria to start the mother on dual PMTCT therapy. In conclusion there is an urgent need for barriers such as lack of staff, lack of space, lack of training on PMTCT and standard procedures for follow up of patients to be addressed in order to ensure the successful scaling up of PMTCT.
- Full Text:
- Date Issued: 2010
- Authors: Singh, Vikesh
- Date: 2010
- Subjects: HIV infections -- Transmission -- South Africa , AIDS (Disease) in pregnancy -- Prevention -- South Africa , Antiretroviral agents
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:10138 , http://hdl.handle.net/10948/1374 , HIV infections -- Transmission -- South Africa , AIDS (Disease) in pregnancy -- Prevention -- South Africa , Antiretroviral agents
- Description: Antiretroviral drugs taken during pregnancy, reduce the rates of mother-to-child transmission from 35 percent to as low as 1 to 2 percent (UNAIDS, 2009). In 2002, the Prevention of Mother-to-Child Transmission (PMTCT) programme was implemented in South Africa. Studies on the implementation of the PMTCT programme have shown that understaffed and under-developed health care facilities were key barriers to the provision of PMTCT services (Health Systems Trust, 2002: 6; Skinner et al., 2003). The aim of this study was to assess the challenges experienced by health care workers working in public sector facilities in the Nelson Mandela Metropole after implementation of the dual therapy PMTCT programme. Four areas were investigated: Infrastructure; Drug Supply Management; Clinic Procedures and Staffing. A quantitative descriptive study was conducted in August 2009 at nine public health care facilities in the Nelson Mandela Metropole, South Africa. Questionnaires were issued to 81 nurses and 41 pharmacy personnel (pharmacists and pharmacist assistants). Checklist audit forms were issued to the Facility Manager of each facility and completed with the researcher. The key findings for Infrastructure were lack of space at patient waiting rooms (9; 100 percent n=9), counselling area (5; 55.5 percent; n=9), nurse consultation rooms (6; 66.6 percent; n=9), storage areas (5; 55.5 percent; n=9) and filing areas (7; 77.7 percent; n=9). The key findings for Drug Supply Management were none of the dispensaries (0 percent; n=10) were fully compliant with Good Pharmacy Practice, pharmacy personnel indicated that there were no stock cards for medication (13; 31.7 percent; n=41); there was less than two weeks supply of buffer stock kept for zidovudine and nevirapine (13; 35.1percent; n=37) and medication orders were placed without any reference to minimum and maximum levels of medication (15; 36.5 percent; n=41) . The key findings for Clinic Procedures were only two facilities followed up on patients that had missed appointments (22.2 percent; n=9) and four facilities (44.4 percent; n=9) had a tracking system for patients that had defaulted. Of the nine facilities only three (33.3 percent; n=9) updated patient demographic details regularly. The key findings for Staffing were a shortage of doctors, nurses, counsellors and pharmacists at the facilities. One of the major challenges identified was the lack of training offered on new PMTCT protocols with 56.2 percent (45; n=80) of the nurses stating that no training was provided on the dual PMTCT protocol. Only 54.3 percent (44; n=81) of nurses stated that they knew the criteria to start the mother on dual PMTCT therapy. In conclusion there is an urgent need for barriers such as lack of staff, lack of space, lack of training on PMTCT and standard procedures for follow up of patients to be addressed in order to ensure the successful scaling up of PMTCT.
- Full Text:
- Date Issued: 2010
Implementing capital budgeting for the multinational corporation
- Authors: Wang, Xin
- Date: 2010
- Subjects: International business enterprises -- Accounting
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:8939 , http://hdl.handle.net/10948/1304 , International business enterprises -- Accounting
- Description: There are many reasons to believe that budgeting lies at the heart of business management. Gray et al (2001:324) states that ―budgetary planning and control is the most visible use of accounting information in the management control process. By setting standards of performance and providing feedback by means of variance reports, the accountant supplies much of the fundamental information required for overall planning and control. However, Gray et al (2001:324) point out that capital budgeting decision is limited by the intricacies of the international business environment, which is characterized by economic, social, political, and cultural diversity. Therefore, decisions of capital investments and budgetary controls are more problematic (Gray et al., 2001:14). One of the defining characteristics of the globalization of the world economy in the past two decades has been the spread of multinational corporations' activities across countries, and, as a result, significant increases in global foreign direct investment (FDI) outflow in the 1990s (from R233 billion in 1990 to R1, 379 billion in 2000). For example, the total stock of Chinese direct investment abroad nearly tripled over the 1990s (from $2.2 trillion in 1990 to $6.3 trillion in 2000) as Chinese multinational corporations generated an increasingly large share of world GDP (6.8 percent in 1994 and 8.6 percent in 2000). Multinational corporations have become an important conduit in the global allocation of investment funds. However, the business environment in international markets has been considered volatile; there is no reliable and accurate method to aid 2 multinational corporations about decisions about the international environment. Thus, multinational corporations have encountered risk and challenge. Given the development and challenge of the international environment, this study have been considered to plan over a longer time horizon, develop formal mechanisms to set aside funds for preserving existing facilities, increase automation of the process, and link capital planning decisions to statewide performance goals and strategic plans. This research draws upon existing theoretical determinants of capital budgeting and empirically tests the hypotheses across a sample of multinational corporations in China. Although the sample is from China, the results have important implications for multinational corporations based in other countries. This paper is composed of four parts. The first part briefly gives both a theoretical and practical overview of multinational capital budgeting analysis. The second part discusses the data collection techniques and the questionnaire design used in this study. The third part provides some important findings of this research. The last section offers some conclusions from this study.
- Full Text:
- Date Issued: 2010
- Authors: Wang, Xin
- Date: 2010
- Subjects: International business enterprises -- Accounting
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:8939 , http://hdl.handle.net/10948/1304 , International business enterprises -- Accounting
- Description: There are many reasons to believe that budgeting lies at the heart of business management. Gray et al (2001:324) states that ―budgetary planning and control is the most visible use of accounting information in the management control process. By setting standards of performance and providing feedback by means of variance reports, the accountant supplies much of the fundamental information required for overall planning and control. However, Gray et al (2001:324) point out that capital budgeting decision is limited by the intricacies of the international business environment, which is characterized by economic, social, political, and cultural diversity. Therefore, decisions of capital investments and budgetary controls are more problematic (Gray et al., 2001:14). One of the defining characteristics of the globalization of the world economy in the past two decades has been the spread of multinational corporations' activities across countries, and, as a result, significant increases in global foreign direct investment (FDI) outflow in the 1990s (from R233 billion in 1990 to R1, 379 billion in 2000). For example, the total stock of Chinese direct investment abroad nearly tripled over the 1990s (from $2.2 trillion in 1990 to $6.3 trillion in 2000) as Chinese multinational corporations generated an increasingly large share of world GDP (6.8 percent in 1994 and 8.6 percent in 2000). Multinational corporations have become an important conduit in the global allocation of investment funds. However, the business environment in international markets has been considered volatile; there is no reliable and accurate method to aid 2 multinational corporations about decisions about the international environment. Thus, multinational corporations have encountered risk and challenge. Given the development and challenge of the international environment, this study have been considered to plan over a longer time horizon, develop formal mechanisms to set aside funds for preserving existing facilities, increase automation of the process, and link capital planning decisions to statewide performance goals and strategic plans. This research draws upon existing theoretical determinants of capital budgeting and empirically tests the hypotheses across a sample of multinational corporations in China. Although the sample is from China, the results have important implications for multinational corporations based in other countries. This paper is composed of four parts. The first part briefly gives both a theoretical and practical overview of multinational capital budgeting analysis. The second part discusses the data collection techniques and the questionnaire design used in this study. The third part provides some important findings of this research. The last section offers some conclusions from this study.
- Full Text:
- Date Issued: 2010
Improving customer service through effective supply chain management in a pharmaceutical company
- Authors: Rothner, Donne
- Date: 2010
- Subjects: Customer services -- South Africa , Customer services -- Management , Customer services -- South Africa -- Quality control , Business logistics -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8625 , http://hdl.handle.net/10948/1490 , Customer services -- South Africa , Customer services -- Management , Customer services -- South Africa -- Quality control , Business logistics -- South Africa
- Description: All organisations compete on the basis of service. In today‘s highly competitive world, organisations need to compete to retain their customers and to offer good customer service that will give them a competitive advantage. In the South African pharmaceutical market, the introduction of the Single Exit Price (SEP) and generic substitution have led to the price of equivalent medicines no longer being the differentiating factor in a customer deciding which manufacturer‘s product to purchase. The availability of generic medicines at the pharmacy or hospital has become the differentiating factor. Two types of customers exist in any organisation, namely, external customers and internal customers. Much has been written about the external customer, but less about the internal customer. Many managers do not perceive internal customer service as a priority. Any organisation attempting to deliver quality service to their external customers must begin by serving the needs of their internal customers. Internal service quality is characterised by the attitudes that people have towards one another and in the way that employees serve one another inside the organisation. By improving customer service, the organisation can improve its profitability, sustainability and customer retention. The aim of this study was to determine whether the levels of internal customer service between the three sections of Aspen Pharmacare are optimal. Determining the current performance levels between the staff of the sections will assist in highlighting the areas that require attention. The three sections of Aspen Pharmacare that are internal customers of one another and have been used in the study are: - production; - demand planning; and - distribution. The results of the study show that all three sections rate three service quality dimensions (communication, tangibles and reliability) as important. The results were used to develop an internal customer service model for Aspen Pharmacare.
- Full Text:
- Date Issued: 2010
- Authors: Rothner, Donne
- Date: 2010
- Subjects: Customer services -- South Africa , Customer services -- Management , Customer services -- South Africa -- Quality control , Business logistics -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8625 , http://hdl.handle.net/10948/1490 , Customer services -- South Africa , Customer services -- Management , Customer services -- South Africa -- Quality control , Business logistics -- South Africa
- Description: All organisations compete on the basis of service. In today‘s highly competitive world, organisations need to compete to retain their customers and to offer good customer service that will give them a competitive advantage. In the South African pharmaceutical market, the introduction of the Single Exit Price (SEP) and generic substitution have led to the price of equivalent medicines no longer being the differentiating factor in a customer deciding which manufacturer‘s product to purchase. The availability of generic medicines at the pharmacy or hospital has become the differentiating factor. Two types of customers exist in any organisation, namely, external customers and internal customers. Much has been written about the external customer, but less about the internal customer. Many managers do not perceive internal customer service as a priority. Any organisation attempting to deliver quality service to their external customers must begin by serving the needs of their internal customers. Internal service quality is characterised by the attitudes that people have towards one another and in the way that employees serve one another inside the organisation. By improving customer service, the organisation can improve its profitability, sustainability and customer retention. The aim of this study was to determine whether the levels of internal customer service between the three sections of Aspen Pharmacare are optimal. Determining the current performance levels between the staff of the sections will assist in highlighting the areas that require attention. The three sections of Aspen Pharmacare that are internal customers of one another and have been used in the study are: - production; - demand planning; and - distribution. The results of the study show that all three sections rate three service quality dimensions (communication, tangibles and reliability) as important. The results were used to develop an internal customer service model for Aspen Pharmacare.
- Full Text:
- Date Issued: 2010
Improving economic development through effective communication strategies in Nelson Mandela Bay
- Authors: Headbush, Shambalda
- Date: 2010
- Subjects: Communication in economic development
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8666 , http://hdl.handle.net/10948/1246 , Communication in economic development
- Description: The purpose of this study is to improve Local Economic Development (LED) through effective communication strategies between Local Government and the Private sector in Nelson Mandela Bay. The study has been carried out by means of a literature and a primary study. Effective communication is one of the key elements which contribute to the success of Local Economic Development implementation. The communication strategies in Local Economic Development have been discussed and analysed to determine the ineffective methods of communication in Local Economic Development implementation. The literature indicated that a good communication strategy is determining the most effective method of communicating with ones’ target audience. The findings of the primary study revealed that the communication strategy between the stakeholders was not fully maximised in improving Local Economic Development implementation. It also revealed secondary factors that contributed to the ineffectiveness of Local Economic Development implementation. In order to improve the current communication strategies, the researcher recommended that new forms of communication medium between Government and the Private sector could be introduced. Lastly, the secondary factors which contribute to ineffective Local Economic Development implementation were analysed and recommendations were suggested.
- Full Text:
- Date Issued: 2010
- Authors: Headbush, Shambalda
- Date: 2010
- Subjects: Communication in economic development
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8666 , http://hdl.handle.net/10948/1246 , Communication in economic development
- Description: The purpose of this study is to improve Local Economic Development (LED) through effective communication strategies between Local Government and the Private sector in Nelson Mandela Bay. The study has been carried out by means of a literature and a primary study. Effective communication is one of the key elements which contribute to the success of Local Economic Development implementation. The communication strategies in Local Economic Development have been discussed and analysed to determine the ineffective methods of communication in Local Economic Development implementation. The literature indicated that a good communication strategy is determining the most effective method of communicating with ones’ target audience. The findings of the primary study revealed that the communication strategy between the stakeholders was not fully maximised in improving Local Economic Development implementation. It also revealed secondary factors that contributed to the ineffectiveness of Local Economic Development implementation. In order to improve the current communication strategies, the researcher recommended that new forms of communication medium between Government and the Private sector could be introduced. Lastly, the secondary factors which contribute to ineffective Local Economic Development implementation were analysed and recommendations were suggested.
- Full Text:
- Date Issued: 2010
Improving project implementation in firms
- Authors: Hassen, Ismail
- Date: 2010
- Subjects: Project management -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8667 , http://hdl.handle.net/10948/1245 , Project management -- South Africa
- Description: Project implementation appears to be one the most difficult aspects of a manager’s job. The purpose of project management is to forecast or anticipate potential dangers and problems that may jeopardise the success of a project and then to plan, organise and control activities that will lead to the successful completion of projects in spite of all the envisaged risks. It is estimated that more than 80% of projects run late or over budget. Such failure often sinks small firms and erodes profits of larger organisations. Project implementation is therefore critical to the success of both small and big firms. The primary objective of this study is to improve project management in firms by investigating the variables that influence project implementation. More specifically, the study investigates the influence of organisational communication, leadership, business process management and resistance to change on project implementation. The sample consisted of 170 employees in a cross-section of industries. The sample was stratified to include senior managers, managers, supervisors and lower level employees. The empirical results show that organisational communication, participatory leadership, retention of the status quo and goal-oriented leadership increase project implementation, while resistance to change decreases project implementation.
- Full Text:
- Date Issued: 2010
- Authors: Hassen, Ismail
- Date: 2010
- Subjects: Project management -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8667 , http://hdl.handle.net/10948/1245 , Project management -- South Africa
- Description: Project implementation appears to be one the most difficult aspects of a manager’s job. The purpose of project management is to forecast or anticipate potential dangers and problems that may jeopardise the success of a project and then to plan, organise and control activities that will lead to the successful completion of projects in spite of all the envisaged risks. It is estimated that more than 80% of projects run late or over budget. Such failure often sinks small firms and erodes profits of larger organisations. Project implementation is therefore critical to the success of both small and big firms. The primary objective of this study is to improve project management in firms by investigating the variables that influence project implementation. More specifically, the study investigates the influence of organisational communication, leadership, business process management and resistance to change on project implementation. The sample consisted of 170 employees in a cross-section of industries. The sample was stratified to include senior managers, managers, supervisors and lower level employees. The empirical results show that organisational communication, participatory leadership, retention of the status quo and goal-oriented leadership increase project implementation, while resistance to change decreases project implementation.
- Full Text:
- Date Issued: 2010
Improving the sales success at Avusa Publishing Eastern Cape
- Authors: Gerwel, Ettienne
- Date: 2010
- Subjects: Sales management -- South Africa , Advertising, Newspaper -- South Africa , Selling
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8634 , http://hdl.handle.net/10948/1453 , Sales management -- South Africa , Advertising, Newspaper -- South Africa , Selling
- Description: Avusa Publishing (East Cape) (APEC) publishes several of the oldest and best known newspaper products in the Eastern Cape. The Eastern Province Herald is currently the oldest daily morning newspaper in South Africa and the average daily circulation of the paper is 25 000. Its main distribution is in the Nelson Mandela Bay Metropolitan area, as well as the area up to the Garden Route and as far East as Port Alfred. APEC also publishes the Weekend Post. According to the financial statements and circulation and advertisement figures of the company, the revenue generated by the company has not increased, but stayed stagnant. In addition to this, the daily circulation of the flagship publication, The Herald, has decreased from 29 000 in 2005 to 24 000 in 2008. As the company only generates revenue from two sources, namely advertising sales and the sale of newspapers, the above mentioned situation negatively affects the financial wellbeing of the company. The management dilemma that needed to be researched was how APEC's circulation and advertising income could be increased. The primary objective of this study was therefore to improve APEC's sales success by investigating the determinants of such sales success. More specifically, the study investigated the influence of determinants such as newsworthiness, value proposition, brand awareness, customer service, customer loyalty, credibility and new media on sales success, as measured by increased circulation and advertising revenue. Convenience sampling was used to select 287 employees working for the company. A mail survey was conducted among these 287 employees, but only 114 usable questionnaires were returned (a response rate of 40 percent). The empirical results revealed that brand awareness, customer loyalty and the use of new media technologies exerted a significantly positive influence on the sales success of APEC. The results further showed that newsworthiness, editorial credibility, value proposition and customer service exerted no significant influence on the APEC’s sales success. Despite the latter findings, the results revealed that there was a high level of trust and loyalty in the editorial content of APEC, as well as the perception of good value for money among both readers and advertisers. The managerial implications of these findings are discussed and areas of future research are recommended.
- Full Text:
- Date Issued: 2010
- Authors: Gerwel, Ettienne
- Date: 2010
- Subjects: Sales management -- South Africa , Advertising, Newspaper -- South Africa , Selling
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8634 , http://hdl.handle.net/10948/1453 , Sales management -- South Africa , Advertising, Newspaper -- South Africa , Selling
- Description: Avusa Publishing (East Cape) (APEC) publishes several of the oldest and best known newspaper products in the Eastern Cape. The Eastern Province Herald is currently the oldest daily morning newspaper in South Africa and the average daily circulation of the paper is 25 000. Its main distribution is in the Nelson Mandela Bay Metropolitan area, as well as the area up to the Garden Route and as far East as Port Alfred. APEC also publishes the Weekend Post. According to the financial statements and circulation and advertisement figures of the company, the revenue generated by the company has not increased, but stayed stagnant. In addition to this, the daily circulation of the flagship publication, The Herald, has decreased from 29 000 in 2005 to 24 000 in 2008. As the company only generates revenue from two sources, namely advertising sales and the sale of newspapers, the above mentioned situation negatively affects the financial wellbeing of the company. The management dilemma that needed to be researched was how APEC's circulation and advertising income could be increased. The primary objective of this study was therefore to improve APEC's sales success by investigating the determinants of such sales success. More specifically, the study investigated the influence of determinants such as newsworthiness, value proposition, brand awareness, customer service, customer loyalty, credibility and new media on sales success, as measured by increased circulation and advertising revenue. Convenience sampling was used to select 287 employees working for the company. A mail survey was conducted among these 287 employees, but only 114 usable questionnaires were returned (a response rate of 40 percent). The empirical results revealed that brand awareness, customer loyalty and the use of new media technologies exerted a significantly positive influence on the sales success of APEC. The results further showed that newsworthiness, editorial credibility, value proposition and customer service exerted no significant influence on the APEC’s sales success. Despite the latter findings, the results revealed that there was a high level of trust and loyalty in the editorial content of APEC, as well as the perception of good value for money among both readers and advertisers. The managerial implications of these findings are discussed and areas of future research are recommended.
- Full Text:
- Date Issued: 2010
Influences on construction project delivery time
- Authors: Olatunji, Aiyetan Ayodeji
- Date: 2010
- Subjects: Construction industry -- South Africa -- Management , Project management -- South Africa , Construction industry -- Economic aspects -- South Africa , Construction industry -- Technological innovations -- South Africa , Construction industry -- Labor productivity -- South Africa
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: vital:9681 , http://hdl.handle.net/10948/1548 , Construction industry -- South Africa -- Management , Project management -- South Africa , Construction industry -- Economic aspects -- South Africa , Construction industry -- Technological innovations -- South Africa , Construction industry -- Labor productivity -- South Africa
- Description: Construction delays are a global phenomenon. Factors causing construction delays in construction projects differ from country to country, due to different prevailing conditions. The prevailing conditions that could exert an influence on project delivery time are: political, economic, and physical factors as well as level of technological development; management style, and construction techniques. The construction industry is a major player in the economy, generating both employment and wealth. However, many projects experience extensive delays and thereby exceed initial time and cost estimates. This study aims at determining the causes of delays in project delivery in South Africa; evolving interventions, and developing a model for the delivery of projects on time. Inferential and linear regression statistical tools were used in the analysis of data for the study. The sample population consists of architects, builders, quantity surveyors, structural engineers, and clients, and the metropolitan cities of five provinces constituted the geographical delimitation of the study. The provinces are: Eastern Cape; Free State; Gauteng; KwaZulu-Natal, and Western Cape. The metropolitan cities are: Bloemfontein; Cape Town; Durban; Johannesburg, and Port Elizabeth. Findings which negatively influence project delivery time in South Africa include the following: lack of adequate planning; management style; the lack of constructability reviews of designs; inadequate motivation of workers; economic policies; lack of prompt payment to contractors, and quality of management during design and construction. Recommendations include: (1) The introduction of the following courses in built environment tertiary education � quality management competences; operational planning; design management, and generic management; (2) pre-qualification of suppliers; (3) inclusion of the following in tender documentation � human resource schedule; plant and equipment schedule; quality assurance plan, and work schedule; (4) appointment of materials specialists on a large projects; (5) the model developed should be adopted for use in the South African construction industry for the delivery of projects on time, and (6) the linear regression equation: Y = 13.1159 + 1.1341x or 35.3 percent addition on time for the estimation of project delivery time.
- Full Text:
- Date Issued: 2010
- Authors: Olatunji, Aiyetan Ayodeji
- Date: 2010
- Subjects: Construction industry -- South Africa -- Management , Project management -- South Africa , Construction industry -- Economic aspects -- South Africa , Construction industry -- Technological innovations -- South Africa , Construction industry -- Labor productivity -- South Africa
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: vital:9681 , http://hdl.handle.net/10948/1548 , Construction industry -- South Africa -- Management , Project management -- South Africa , Construction industry -- Economic aspects -- South Africa , Construction industry -- Technological innovations -- South Africa , Construction industry -- Labor productivity -- South Africa
- Description: Construction delays are a global phenomenon. Factors causing construction delays in construction projects differ from country to country, due to different prevailing conditions. The prevailing conditions that could exert an influence on project delivery time are: political, economic, and physical factors as well as level of technological development; management style, and construction techniques. The construction industry is a major player in the economy, generating both employment and wealth. However, many projects experience extensive delays and thereby exceed initial time and cost estimates. This study aims at determining the causes of delays in project delivery in South Africa; evolving interventions, and developing a model for the delivery of projects on time. Inferential and linear regression statistical tools were used in the analysis of data for the study. The sample population consists of architects, builders, quantity surveyors, structural engineers, and clients, and the metropolitan cities of five provinces constituted the geographical delimitation of the study. The provinces are: Eastern Cape; Free State; Gauteng; KwaZulu-Natal, and Western Cape. The metropolitan cities are: Bloemfontein; Cape Town; Durban; Johannesburg, and Port Elizabeth. Findings which negatively influence project delivery time in South Africa include the following: lack of adequate planning; management style; the lack of constructability reviews of designs; inadequate motivation of workers; economic policies; lack of prompt payment to contractors, and quality of management during design and construction. Recommendations include: (1) The introduction of the following courses in built environment tertiary education � quality management competences; operational planning; design management, and generic management; (2) pre-qualification of suppliers; (3) inclusion of the following in tender documentation � human resource schedule; plant and equipment schedule; quality assurance plan, and work schedule; (4) appointment of materials specialists on a large projects; (5) the model developed should be adopted for use in the South African construction industry for the delivery of projects on time, and (6) the linear regression equation: Y = 13.1159 + 1.1341x or 35.3 percent addition on time for the estimation of project delivery time.
- Full Text:
- Date Issued: 2010
Innovation in post production stage of print Newspaper
- Authors: Fayo, Sicelo Nathaniel
- Date: 2010
- Subjects: Newspaper publishing -- Technological innovations , Newspapers -- Circulation , Newspapers -- Marketing
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8614 , http://hdl.handle.net/10948/1544 , Newspaper publishing -- Technological innovations , Newspapers -- Circulation , Newspapers -- Marketing
- Description: Print newspapers in South Africa are the oldest formal mode of news and information dissemination but which has come under tremendous pressure with the advent and spread of technological innovation involving information communication infrastructure and processes, but specifically the internet. The main challenge facing print newspapers in terms of circulation growth of print and advertising revenue is speed to market. The internet has not only provided a new avenue for news and information dissemination but has the distinct advantage of tremendous speed to deliver news and information to readers. Meanwhile, print newspapers whose production is still almost entirely dependent on traditional structures, processes and physical mode of delivery are battling to stay afloat as the chase for readers' attention is gaining more ground on digital platforms. This new competition landscape has now cast focus fully on traditional print media‟s production processes competency levels as well as their suitability for the nature of competition posed by digital news platforms. The processes involved in the production of a print newspaper can be described as hybrid (Davis and Heineke. 2005: 220) in that they involve different types of processes at different stages to produce the final product. The focus of this study at Avusa Media (Port Elizabeth) was on the post production processes involving the printing and distribution of printed newspapers with the objective of gaining an understanding of the extent and impact of the information technology advancement in the post production phase of printed newspapers. v In pursuing the goal, the case study research followed a phenomenological paradigm involving exploratory and descriptive research processes as described by Yin (1994) in Collis and Hussey (2003: 69) and Clifford Geertz (1973) in Babbie and Mouton (2005: 272) The research found that the traditional business structure for printed newspapers is increasingly becoming unviable due to poverty of technological innovation in critical parts of the production value chain; namely post production processes that encompass printing and distribution of printed newspapers. The research established and revealed that while there are some technological innovations and advances in the print newspaper publishing industry value chain worldwide, they are not only severely limited and disjointed but are also seemingly moving apart rather than towards consolidation in terms of the speed to market need faced by print newspaper publishers.
- Full Text:
- Date Issued: 2010
- Authors: Fayo, Sicelo Nathaniel
- Date: 2010
- Subjects: Newspaper publishing -- Technological innovations , Newspapers -- Circulation , Newspapers -- Marketing
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8614 , http://hdl.handle.net/10948/1544 , Newspaper publishing -- Technological innovations , Newspapers -- Circulation , Newspapers -- Marketing
- Description: Print newspapers in South Africa are the oldest formal mode of news and information dissemination but which has come under tremendous pressure with the advent and spread of technological innovation involving information communication infrastructure and processes, but specifically the internet. The main challenge facing print newspapers in terms of circulation growth of print and advertising revenue is speed to market. The internet has not only provided a new avenue for news and information dissemination but has the distinct advantage of tremendous speed to deliver news and information to readers. Meanwhile, print newspapers whose production is still almost entirely dependent on traditional structures, processes and physical mode of delivery are battling to stay afloat as the chase for readers' attention is gaining more ground on digital platforms. This new competition landscape has now cast focus fully on traditional print media‟s production processes competency levels as well as their suitability for the nature of competition posed by digital news platforms. The processes involved in the production of a print newspaper can be described as hybrid (Davis and Heineke. 2005: 220) in that they involve different types of processes at different stages to produce the final product. The focus of this study at Avusa Media (Port Elizabeth) was on the post production processes involving the printing and distribution of printed newspapers with the objective of gaining an understanding of the extent and impact of the information technology advancement in the post production phase of printed newspapers. v In pursuing the goal, the case study research followed a phenomenological paradigm involving exploratory and descriptive research processes as described by Yin (1994) in Collis and Hussey (2003: 69) and Clifford Geertz (1973) in Babbie and Mouton (2005: 272) The research found that the traditional business structure for printed newspapers is increasingly becoming unviable due to poverty of technological innovation in critical parts of the production value chain; namely post production processes that encompass printing and distribution of printed newspapers. The research established and revealed that while there are some technological innovations and advances in the print newspaper publishing industry value chain worldwide, they are not only severely limited and disjointed but are also seemingly moving apart rather than towards consolidation in terms of the speed to market need faced by print newspaper publishers.
- Full Text:
- Date Issued: 2010
Integer optimisation for the selection of a fantasy league cricket team
- Authors: Brettenny, Warren James
- Date: 2010
- Subjects: Sports -- Research -- Methodology , Teamwork (Sports) , Cricket players
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10565 , http://hdl.handle.net/10948/1230 , Sports -- Research -- Methodology , Teamwork (Sports) , Cricket players
- Description: Sports fans often scrutinise the team selection strategies employed by their favourite team's coach or selection panel. Many of these fans believe that they can perform the selection process far better than those tasked with the responsibility. Fantasy leagues, provide a platform for fans to test their hand at this selection procedure. Twenty20 cricket is a new and exciting form of cricket and has become very popular in recent years. This research focuses on bringing these concepts together by proposing a binary integer program to determine a team selection strategy for fantasy league cricket. This is done in a Twenty20 setting. The approach used in this study focuses on evaluating the effectiveness of previously developed performance measures in a fantasy league setting. Adjustments to these measures are made and new measures are proposed. These measures are then used to select a fantasy league team using a prospective approach. This is done to provide fantasy league participants with a mathematical procedure for fantasy league team selection.
- Full Text:
- Date Issued: 2010
- Authors: Brettenny, Warren James
- Date: 2010
- Subjects: Sports -- Research -- Methodology , Teamwork (Sports) , Cricket players
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10565 , http://hdl.handle.net/10948/1230 , Sports -- Research -- Methodology , Teamwork (Sports) , Cricket players
- Description: Sports fans often scrutinise the team selection strategies employed by their favourite team's coach or selection panel. Many of these fans believe that they can perform the selection process far better than those tasked with the responsibility. Fantasy leagues, provide a platform for fans to test their hand at this selection procedure. Twenty20 cricket is a new and exciting form of cricket and has become very popular in recent years. This research focuses on bringing these concepts together by proposing a binary integer program to determine a team selection strategy for fantasy league cricket. This is done in a Twenty20 setting. The approach used in this study focuses on evaluating the effectiveness of previously developed performance measures in a fantasy league setting. Adjustments to these measures are made and new measures are proposed. These measures are then used to select a fantasy league team using a prospective approach. This is done to provide fantasy league participants with a mathematical procedure for fantasy league team selection.
- Full Text:
- Date Issued: 2010
Integrated teaching strategies model for improved scientific literacy in second-language learners
- Villanueva, Mary Grace Flores
- Authors: Villanueva, Mary Grace Flores
- Date: 2010
- Subjects: Science -- Study and teaching (Elementary) -- South Africa , Science -- South Africa -- Methodology , Science -- Curricula
- Language: English
- Type: Thesis , Doctoral , DEd
- Identifier: vital:9514 , http://hdl.handle.net/10948/1107 , Science -- Study and teaching (Elementary) -- South Africa , Science -- South Africa -- Methodology , Science -- Curricula
- Description: The importance of a scientifically literate society is currently acknowledged both internationally and South Africa. The notion of scientific literacy in South Africa has emerged largely due to the government’s recognition of the role that science and technology plays in economic growth, employment creation, social redress and social development. However, in light of South Africa’s learner performance on international and national assessments such as TIMMS (2003) and PIRLS (2006), as well as the problems of teaching and learning in a second language, there appears to be a primary and pressing need to develop learners’ fundamental sense of scientific literacy (Norris & Phillips, 2003). Expanding learners’ ability to read, write and communicate in science may provide the necessary framework for engaging learners in the critical principles and foundations of the scientific endeavour (Hand, Prain, & Yore, 2001). As such, this study focuses on equipping and training grade six and seven science teachers to develop scientifically literate learners via professional development workshops with a strategy that supports reading, writing, talking and conducting (‘doing’) science through scientific investigations. The typology of triangulation and the mixed method research approach was supported by a fully mixed, concurrent, and equal status design (Leech & Onwuegbuzi, 2007). Quantitative data were collected from the baseline and post-intervention testing of learners’ problem solving skills, as well as their literacy skills in English and isiXhosa. Qualitative measures were generated through classroom observations, teacher interviews and learners’ science notebooks. The study was conducted in two different milieus in the Eastern Cape, South Africa. The first setting, in the rural area of Tyumie Valley near the Hogsback Mountains, was comprised of a sample of grade six and seven (multi-grade classrooms) teachers (n=7) and learners (n=168) from five experimental schools and two comparison schools. The second setting, in the urban townships area east of Port Elizabeth, was comprised of a sample of grade six teachers (n=8) and learners (n=675) from six experimental schools and two comparison schools. Mean differences between the experimental and the comparison groups were computed for the Raven’s Standard Progressive Matrices (RSPM) and the literacy tests, and the data generated were treated with an Analysis of Covariance (ANCOVA). The data suggest that the scientific literacy strategy improved the experimental learners’ problem solving skills. Both experimental groups demonstrated greater gains than that of the comparison schools. However, statistically significant improvements were only detected in Port Elizabeth. Improvements in learners’ literacy skills in isiXhosa and English varied according to each milieu. While the teachers initially identified challenges to learners’ reading and writing abilities, the analysis of learners’ science notebooks suggested that they used writings to support their investigations. Some teachers cited difficulties with certain aspects of the model, such as problems with developing an investigable question and argumentation, yet overall, teachers found the strategy useful for developing learners’ language skills, as well for strengthening their pedagogical practices in science. Teachers’ gradual improvements in the use of the model suggest that they were able to use the scientific literacy strategy to support the cognitive and linguistic development of second-language learners.
- Full Text:
- Date Issued: 2010
- Authors: Villanueva, Mary Grace Flores
- Date: 2010
- Subjects: Science -- Study and teaching (Elementary) -- South Africa , Science -- South Africa -- Methodology , Science -- Curricula
- Language: English
- Type: Thesis , Doctoral , DEd
- Identifier: vital:9514 , http://hdl.handle.net/10948/1107 , Science -- Study and teaching (Elementary) -- South Africa , Science -- South Africa -- Methodology , Science -- Curricula
- Description: The importance of a scientifically literate society is currently acknowledged both internationally and South Africa. The notion of scientific literacy in South Africa has emerged largely due to the government’s recognition of the role that science and technology plays in economic growth, employment creation, social redress and social development. However, in light of South Africa’s learner performance on international and national assessments such as TIMMS (2003) and PIRLS (2006), as well as the problems of teaching and learning in a second language, there appears to be a primary and pressing need to develop learners’ fundamental sense of scientific literacy (Norris & Phillips, 2003). Expanding learners’ ability to read, write and communicate in science may provide the necessary framework for engaging learners in the critical principles and foundations of the scientific endeavour (Hand, Prain, & Yore, 2001). As such, this study focuses on equipping and training grade six and seven science teachers to develop scientifically literate learners via professional development workshops with a strategy that supports reading, writing, talking and conducting (‘doing’) science through scientific investigations. The typology of triangulation and the mixed method research approach was supported by a fully mixed, concurrent, and equal status design (Leech & Onwuegbuzi, 2007). Quantitative data were collected from the baseline and post-intervention testing of learners’ problem solving skills, as well as their literacy skills in English and isiXhosa. Qualitative measures were generated through classroom observations, teacher interviews and learners’ science notebooks. The study was conducted in two different milieus in the Eastern Cape, South Africa. The first setting, in the rural area of Tyumie Valley near the Hogsback Mountains, was comprised of a sample of grade six and seven (multi-grade classrooms) teachers (n=7) and learners (n=168) from five experimental schools and two comparison schools. The second setting, in the urban townships area east of Port Elizabeth, was comprised of a sample of grade six teachers (n=8) and learners (n=675) from six experimental schools and two comparison schools. Mean differences between the experimental and the comparison groups were computed for the Raven’s Standard Progressive Matrices (RSPM) and the literacy tests, and the data generated were treated with an Analysis of Covariance (ANCOVA). The data suggest that the scientific literacy strategy improved the experimental learners’ problem solving skills. Both experimental groups demonstrated greater gains than that of the comparison schools. However, statistically significant improvements were only detected in Port Elizabeth. Improvements in learners’ literacy skills in isiXhosa and English varied according to each milieu. While the teachers initially identified challenges to learners’ reading and writing abilities, the analysis of learners’ science notebooks suggested that they used writings to support their investigations. Some teachers cited difficulties with certain aspects of the model, such as problems with developing an investigable question and argumentation, yet overall, teachers found the strategy useful for developing learners’ language skills, as well for strengthening their pedagogical practices in science. Teachers’ gradual improvements in the use of the model suggest that they were able to use the scientific literacy strategy to support the cognitive and linguistic development of second-language learners.
- Full Text:
- Date Issued: 2010
Investigating factors that negatively influence lean implementation in the Eastern Cape automotive industry
- Authors: Camagu, Sibo
- Date: 2010
- Subjects: Lean manufacturing -- South Africa -- Eastern Cape , Production management -- South Africa -- Eastern Cape , Industrial efficiency , Automobile industry and trade
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8655 , http://hdl.handle.net/10948/1360 , Lean manufacturing -- South Africa -- Eastern Cape , Production management -- South Africa -- Eastern Cape , Industrial efficiency , Automobile industry and trade
- Description: In this intensely competitive environment of the global economy, the survival of even the most established manufacturers depends on their ability to continuously improve quality whilst reducing costs. The resulting productivity of producing more with less is the only key to market leadership and sustainable competitive advantage. Changing production methods from mass-production to Lean Manufacturing has become the essential practise for successful manufacturers (Rogers and Sim, 2009). The purpose of this study is to investigate what factors negate the adoption and implementation of Lean Manufacturing as a means to gain competitive advantage. The focus was on companies that have participated in the AIDC Tirisano cluster programme. The study investigated what effect Organisational Culture, Leadership Behaviours, Employee Involvement and Strategy Integration have on Lean Manufacturing adoption and implementation. This study applied the mixed methodologies of qualitative and quantitative approaches using methodological triangulation. A cross sectional analytical survey approach in a descriptive case study was undertaken. The findings from the questions and the interviews from the respondents who participated in the survey indicated that the practices in some companies enable the successful adoption and implementation of Lean Manufacturing whilst in some others the practices will negatively affect the adoption and implementation. The study concludes by stating that South African automotive component manufacturers are under immense pressure to improve quality and reduce costs. Initiatives like Lean Manufacturing should be undertaken in order to bring about these improvements. But this improvement comes about by changing the current way of doing things. Companies need to undertake a total approach when implementing Lean as part of the business strategy and this must be driven by management as leaders and a team culture that involves all employees needs to be present.
- Full Text:
- Date Issued: 2010
- Authors: Camagu, Sibo
- Date: 2010
- Subjects: Lean manufacturing -- South Africa -- Eastern Cape , Production management -- South Africa -- Eastern Cape , Industrial efficiency , Automobile industry and trade
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8655 , http://hdl.handle.net/10948/1360 , Lean manufacturing -- South Africa -- Eastern Cape , Production management -- South Africa -- Eastern Cape , Industrial efficiency , Automobile industry and trade
- Description: In this intensely competitive environment of the global economy, the survival of even the most established manufacturers depends on their ability to continuously improve quality whilst reducing costs. The resulting productivity of producing more with less is the only key to market leadership and sustainable competitive advantage. Changing production methods from mass-production to Lean Manufacturing has become the essential practise for successful manufacturers (Rogers and Sim, 2009). The purpose of this study is to investigate what factors negate the adoption and implementation of Lean Manufacturing as a means to gain competitive advantage. The focus was on companies that have participated in the AIDC Tirisano cluster programme. The study investigated what effect Organisational Culture, Leadership Behaviours, Employee Involvement and Strategy Integration have on Lean Manufacturing adoption and implementation. This study applied the mixed methodologies of qualitative and quantitative approaches using methodological triangulation. A cross sectional analytical survey approach in a descriptive case study was undertaken. The findings from the questions and the interviews from the respondents who participated in the survey indicated that the practices in some companies enable the successful adoption and implementation of Lean Manufacturing whilst in some others the practices will negatively affect the adoption and implementation. The study concludes by stating that South African automotive component manufacturers are under immense pressure to improve quality and reduce costs. Initiatives like Lean Manufacturing should be undertaken in order to bring about these improvements. But this improvement comes about by changing the current way of doing things. Companies need to undertake a total approach when implementing Lean as part of the business strategy and this must be driven by management as leaders and a team culture that involves all employees needs to be present.
- Full Text:
- Date Issued: 2010
Investigating science teachers' perceptions of the nature of science in the context of curriculum reform in South Africa
- Kurup, Rajasekhar Thanukkothu Sankar Pillai
- Authors: Kurup, Rajasekhar Thanukkothu Sankar Pillai
- Date: 2010
- Subjects: Science -- Methodology -- South Africa , Science -- Study and teaching -- Philosophy , Science -- Study and teaching -- South Africa -- Evaluation , Science -- Study and teaching -- Curricula -- South Africa , Science -- Study and teaching -- South Africa
- Language: English
- Type: Thesis , Doctoral , DEd
- Identifier: vital:9509 , http://hdl.handle.net/10948/1175 , Science -- Methodology -- South Africa , Science -- Study and teaching -- Philosophy , Science -- Study and teaching -- South Africa -- Evaluation , Science -- Study and teaching -- Curricula -- South Africa , Science -- Study and teaching -- South Africa
- Description: An adequate understanding of the nature of science (NOS) has become increasingly important for science teachers in South Africa as comprehensive curricular reforms over the past decade include promoting informed understandings of the ontological and epistemological bases of scientific knowledge and the methods of science. The main objective of this study was to explore the NOS understandings held by a sample of science teachers in the Eastern Cape Province of South Africa. Data were generated via questionnaires (n=136), semi-structured interviews (n=31), and classroom observations (n=8). The teacher interviews, which were informed by the questionnaire data, enabled further interrogation of the teachers’ philosophical positions. Their classroom practices were examined within the framework of these philosophical positions and the requirements of the new curriculum. The effect of implicit and explicit instruction in NOS on these teachers’ beliefs and classroom activities was also considered. A mixed-method approach informed by positivist and interpretivist perspectives was used for the collection and analysis of the data. The data suggests that explicit instruction in NOS resulted in more informed conceptions of science and the scientific enterprise, and that these conceptions were reflected, to a degree, in their classroom behaviours. However, it was noted that the teachers in this study often held philosophically eclectic views of the nature of scientific knowledge and how scientists develop ideas. Similarly, the South African National Curriculum Statement portrays science in contrasting ways, i.e. often within a modern/realist framework, but in other instances within postmodern/relativistic understandings (particularly in terms of indigenous knowledge systems). As such, an approach which aims at providing a firm foundation for understanding NOS ideas within a modern/realist perspective before emphasising the postmodern/relativist aspects of the scientific enterprise is suggested for teacher training and curriculum development.
- Full Text:
- Date Issued: 2010
- Authors: Kurup, Rajasekhar Thanukkothu Sankar Pillai
- Date: 2010
- Subjects: Science -- Methodology -- South Africa , Science -- Study and teaching -- Philosophy , Science -- Study and teaching -- South Africa -- Evaluation , Science -- Study and teaching -- Curricula -- South Africa , Science -- Study and teaching -- South Africa
- Language: English
- Type: Thesis , Doctoral , DEd
- Identifier: vital:9509 , http://hdl.handle.net/10948/1175 , Science -- Methodology -- South Africa , Science -- Study and teaching -- Philosophy , Science -- Study and teaching -- South Africa -- Evaluation , Science -- Study and teaching -- Curricula -- South Africa , Science -- Study and teaching -- South Africa
- Description: An adequate understanding of the nature of science (NOS) has become increasingly important for science teachers in South Africa as comprehensive curricular reforms over the past decade include promoting informed understandings of the ontological and epistemological bases of scientific knowledge and the methods of science. The main objective of this study was to explore the NOS understandings held by a sample of science teachers in the Eastern Cape Province of South Africa. Data were generated via questionnaires (n=136), semi-structured interviews (n=31), and classroom observations (n=8). The teacher interviews, which were informed by the questionnaire data, enabled further interrogation of the teachers’ philosophical positions. Their classroom practices were examined within the framework of these philosophical positions and the requirements of the new curriculum. The effect of implicit and explicit instruction in NOS on these teachers’ beliefs and classroom activities was also considered. A mixed-method approach informed by positivist and interpretivist perspectives was used for the collection and analysis of the data. The data suggests that explicit instruction in NOS resulted in more informed conceptions of science and the scientific enterprise, and that these conceptions were reflected, to a degree, in their classroom behaviours. However, it was noted that the teachers in this study often held philosophically eclectic views of the nature of scientific knowledge and how scientists develop ideas. Similarly, the South African National Curriculum Statement portrays science in contrasting ways, i.e. often within a modern/realist framework, but in other instances within postmodern/relativistic understandings (particularly in terms of indigenous knowledge systems). As such, an approach which aims at providing a firm foundation for understanding NOS ideas within a modern/realist perspective before emphasising the postmodern/relativist aspects of the scientific enterprise is suggested for teacher training and curriculum development.
- Full Text:
- Date Issued: 2010
Investigating the benefits of using selected lean techniques at a South African exhaust manufacturer-a case study
- Authors: Louw, Andre
- Date: 2010
- Subjects: Automobile supplies industry , Factories
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8617 , http://hdl.handle.net/10948/1518 , Automobile supplies industry , Factories
- Description: This study investigates the implementation of supermarket-based scheduling of parts at a South African exhaust manufacturing plant. The study firstly investigates the requirements the manufacturer had to contend with in ensuring a valuable contract was won. The nature of the contract is such that it warrants building of a new facility. The design of the facility and the manufacturing processes is of importance as some Lean techniques are employed during these early stages. The research takes the form of a case study and data is collected mainly through interviews with staff, but also from direct observations on the shop-floor. Interviews were conducted with: - key project leaders responsible for the original design and commissioning of the facility; - production managers and technical staff currently operating the plant; and - shop-floor personnel involved in daily production and logistics operations within the plant. The as-built facility and procedures are compared with literature found on the topic of Lean manufacturing. Various findings are recorded, both on conforming to and not conforming to typical Lean theory. Potential changes are suggested in the following areas: - a Pull strategy is proposed to coincide with the appointment of a so-called pacemaker station; - a pacemaker would need to be further supported by a production leveling strategy; - although quality delivered to the customer is reported as very high, potential improvements are still possible by introducing an "at source" approach to reduce rework; and - finally, a Total Productive Maintenance (TPM) program will serve to reduce downtime even further.
- Full Text:
- Date Issued: 2010
- Authors: Louw, Andre
- Date: 2010
- Subjects: Automobile supplies industry , Factories
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8617 , http://hdl.handle.net/10948/1518 , Automobile supplies industry , Factories
- Description: This study investigates the implementation of supermarket-based scheduling of parts at a South African exhaust manufacturing plant. The study firstly investigates the requirements the manufacturer had to contend with in ensuring a valuable contract was won. The nature of the contract is such that it warrants building of a new facility. The design of the facility and the manufacturing processes is of importance as some Lean techniques are employed during these early stages. The research takes the form of a case study and data is collected mainly through interviews with staff, but also from direct observations on the shop-floor. Interviews were conducted with: - key project leaders responsible for the original design and commissioning of the facility; - production managers and technical staff currently operating the plant; and - shop-floor personnel involved in daily production and logistics operations within the plant. The as-built facility and procedures are compared with literature found on the topic of Lean manufacturing. Various findings are recorded, both on conforming to and not conforming to typical Lean theory. Potential changes are suggested in the following areas: - a Pull strategy is proposed to coincide with the appointment of a so-called pacemaker station; - a pacemaker would need to be further supported by a production leveling strategy; - although quality delivered to the customer is reported as very high, potential improvements are still possible by introducing an "at source" approach to reduce rework; and - finally, a Total Productive Maintenance (TPM) program will serve to reduce downtime even further.
- Full Text:
- Date Issued: 2010
Investigating the effect of various film-forming polymers on the evaporation rate of a volatile component in a cosmetic formulation
- Authors: Barnard, Carla
- Date: 2010
- Subjects: Cosmetic delivery systems , Controlled release preparations , Cosmetics , Polymers , Drugs -- Controlled release
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10377 , http://hdl.handle.net/10948/1498 , Cosmetic delivery systems , Controlled release preparations , Cosmetics , Polymers , Drugs -- Controlled release
- Description: The topical application of many substances, including drugs, enzymes, moisturizers and fragrances, contributes largely to the cosmetic and pharmaceutical industries. These components are often volatile in nature and dissipate in a matter of hours. When considering the different types of slow release systems, an overwhelming variety of these systems is available. Each one of the systems is unique in a way, and is designed to perform a particular function, whether it facilitates the controlled release of an active into the body via the skin surface (transdermal delivery) or whether it reduces the rate of loss of an active from the skin surface to the surrounding environment. For the purpose of this study, a previously existing fixative formulation which is believed to reduce the rate of loss of an active component to the environment, through film formation on the skin surface, was investigated. Alternative ingredients or components were incorporated together with the original fixative formulation ingredients into an experimental design which investigates the effect of each group of the components present. 18 formulations with various concentrations of the components within the groups and specified upper and lower limits for each component were formulated. The fixative properties of the formulations were analysed through the incorporation of a fixed amount of a simple fragrance molecule, 4- methoxybenzaldehyde, into each formulation and evaporation studies were conducted in an environmental room at 28±1° C over a period of 5 hours followed by gas chromatography analysis and finally data analyses using statistical methods. The most efficient fixative formulation was established using regression analysis. The fragrance compound in this formulation was found to evaporate at a rate of 0.47 g/L per hour. The least efficient fixative formulation lead to the loss of 0.78 g/L of the fragrance component per hour. From the calculated fragrance concentrations, the rate constant for each individual fixative formulation could be calculated and response surface 8 modelling by backward regression was used in order to determine how each component contributes to the rate of loss of the fragrance compound. Since the sum of the original ingredient and its alternative was constant, each of the original ingredients was coupled directly to its alternative and no conclusion could be made about the contribution of individual components. By increasing the concentration of Hydroxypropylcellulose (HPC) 100K and its alternative HPC 140K, while keeping the effects of the other components constant, a decrease in the rate of fragrance loss was observed. The same conclusion could be made when increasing the concentrations of PEG-12 Dimethicone and its alternative cetyl dimethicone (decreases the evaporation rate). An interaction took place between HPC 100K and PEG-12 dimethicone and their alternatives. The negative effect was, however, not as strong as the combined positive effect on the rate of fragrance loss of the individual components HPC and PEG-12 dimethicone. Evidence suggested that the removal of the components polyvinylpyrrolidone and its alternative, polyurethane-32 (Baycusan® C1003), would improve the effectiveness of the fixative formulation in terms of its slow release properties. A confirmation experiment established that the exclusion of these components from the fixative formulation does improve the “slow release” properties thereof. A larger, more intricate design is required to investigate the effect of each one of the individual components and where the sum of the components (original and its alternative) is not constant.
- Full Text:
- Date Issued: 2010
- Authors: Barnard, Carla
- Date: 2010
- Subjects: Cosmetic delivery systems , Controlled release preparations , Cosmetics , Polymers , Drugs -- Controlled release
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10377 , http://hdl.handle.net/10948/1498 , Cosmetic delivery systems , Controlled release preparations , Cosmetics , Polymers , Drugs -- Controlled release
- Description: The topical application of many substances, including drugs, enzymes, moisturizers and fragrances, contributes largely to the cosmetic and pharmaceutical industries. These components are often volatile in nature and dissipate in a matter of hours. When considering the different types of slow release systems, an overwhelming variety of these systems is available. Each one of the systems is unique in a way, and is designed to perform a particular function, whether it facilitates the controlled release of an active into the body via the skin surface (transdermal delivery) or whether it reduces the rate of loss of an active from the skin surface to the surrounding environment. For the purpose of this study, a previously existing fixative formulation which is believed to reduce the rate of loss of an active component to the environment, through film formation on the skin surface, was investigated. Alternative ingredients or components were incorporated together with the original fixative formulation ingredients into an experimental design which investigates the effect of each group of the components present. 18 formulations with various concentrations of the components within the groups and specified upper and lower limits for each component were formulated. The fixative properties of the formulations were analysed through the incorporation of a fixed amount of a simple fragrance molecule, 4- methoxybenzaldehyde, into each formulation and evaporation studies were conducted in an environmental room at 28±1° C over a period of 5 hours followed by gas chromatography analysis and finally data analyses using statistical methods. The most efficient fixative formulation was established using regression analysis. The fragrance compound in this formulation was found to evaporate at a rate of 0.47 g/L per hour. The least efficient fixative formulation lead to the loss of 0.78 g/L of the fragrance component per hour. From the calculated fragrance concentrations, the rate constant for each individual fixative formulation could be calculated and response surface 8 modelling by backward regression was used in order to determine how each component contributes to the rate of loss of the fragrance compound. Since the sum of the original ingredient and its alternative was constant, each of the original ingredients was coupled directly to its alternative and no conclusion could be made about the contribution of individual components. By increasing the concentration of Hydroxypropylcellulose (HPC) 100K and its alternative HPC 140K, while keeping the effects of the other components constant, a decrease in the rate of fragrance loss was observed. The same conclusion could be made when increasing the concentrations of PEG-12 Dimethicone and its alternative cetyl dimethicone (decreases the evaporation rate). An interaction took place between HPC 100K and PEG-12 dimethicone and their alternatives. The negative effect was, however, not as strong as the combined positive effect on the rate of fragrance loss of the individual components HPC and PEG-12 dimethicone. Evidence suggested that the removal of the components polyvinylpyrrolidone and its alternative, polyurethane-32 (Baycusan® C1003), would improve the effectiveness of the fixative formulation in terms of its slow release properties. A confirmation experiment established that the exclusion of these components from the fixative formulation does improve the “slow release” properties thereof. A larger, more intricate design is required to investigate the effect of each one of the individual components and where the sum of the components (original and its alternative) is not constant.
- Full Text:
- Date Issued: 2010