Granitoid related Sn-W mineralisation with special reference to southern Africa, the Variscan Belt in Europe, and the Malay Peninsula
- Authors: Bentley, Philip Nelson
- Date: 1985
- Subjects: Geotectonic settings , Granitoids , Granites , Tin-tungsten , Mineralisation , Greisen environment , Minerals , Exploration
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4908 , http://hdl.handle.net/10962/d1001568
- Description: A review of the geotectonic settings of granitoids and various tin-tungsten provinces in Europe, Malaysia and southern Africa shows a close spatial and temporal association of mineralisation to S-type ilmenite series granitoids. Granitoids with these affinities are derived from crustal anatexis and are most commonly found in continental collision and different ensialic, intraplate orogenic settings, (e.g. SW England, Malaysia, Namibia) as well as in association with anorogenic magmatism (Nigeria, Brazil, South Africa). Tin-tungsten mineralisation is related to late- to post-tectonic granites, emplaced into areas of substantial tectonic thickening. Crustal anatexis leads to an observable calcalkaline chemical trend, with a source of gabbroic or amphibolite composition through anatexis to; mafic-intermediate enclaves, para-autochthonous anatectic granitoids (tonalite, granodiorite), to intermediate level quartz monzonite, granodiorite, biotite-granite, to late-tectonic highly fractionated muscovite-bearing granites, and high level porphyry intrusions. Mineralisation is spatially related to apical protrusions of the youngest most differentiated granite. Various mineralised environments are recognised, including endogranitic veins, primary disseminations, pegmatites and pipes, and exogranitic stockwork and fissure veins, and replacement bodies. A common factor to all these deposits is the inherent greisen environment, characterised by postmagmatic metasomatic alteration and mineral deposition. Common alteration mineral assemblages include albite, quartz, muscovite, tourmaline, and fluorite ∓ topaz. Ore mineral assemblages commonly display a paragenetic sequence of oxides (cassiterite, wolframite, scheelite), followed by sulphides (molybdenite, pyrite, pyrrhotite, chalcopyrite sphalerite, arsenopyrite/loëllingite, Pb-Bi(Ag) sulphosalts) and then lower temperature carbonates (calcite, siderite, ankerite). Analysis of Pan African orogenic provinces in southern Africa (Damara and Saldanian Provinces) shows there is good potential for applying integrated exploration techniques in search of endo-exogreisen Sn-W systems. Careful analysis and interpretation of granitoid geochemistry (K₂0, Na₂0, FeO/Fe₂0₃, F, B, Sn, W, Mo, Cu, Rb, Sr, Ti, Zr) should aid delineation of Sn-W and Mo-Cu metallogenic provinces in these regions. Magnetic susceptibility determinations should also aid distinction of S-type ilmenite series (less than 1 x lO⁻⁴emu/g ) from I-type magnetite series (more than 1 x lO⁻⁴emu/g ) granitoids
- Full Text:
- Date Issued: 1985
- Authors: Bentley, Philip Nelson
- Date: 1985
- Subjects: Geotectonic settings , Granitoids , Granites , Tin-tungsten , Mineralisation , Greisen environment , Minerals , Exploration
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4908 , http://hdl.handle.net/10962/d1001568
- Description: A review of the geotectonic settings of granitoids and various tin-tungsten provinces in Europe, Malaysia and southern Africa shows a close spatial and temporal association of mineralisation to S-type ilmenite series granitoids. Granitoids with these affinities are derived from crustal anatexis and are most commonly found in continental collision and different ensialic, intraplate orogenic settings, (e.g. SW England, Malaysia, Namibia) as well as in association with anorogenic magmatism (Nigeria, Brazil, South Africa). Tin-tungsten mineralisation is related to late- to post-tectonic granites, emplaced into areas of substantial tectonic thickening. Crustal anatexis leads to an observable calcalkaline chemical trend, with a source of gabbroic or amphibolite composition through anatexis to; mafic-intermediate enclaves, para-autochthonous anatectic granitoids (tonalite, granodiorite), to intermediate level quartz monzonite, granodiorite, biotite-granite, to late-tectonic highly fractionated muscovite-bearing granites, and high level porphyry intrusions. Mineralisation is spatially related to apical protrusions of the youngest most differentiated granite. Various mineralised environments are recognised, including endogranitic veins, primary disseminations, pegmatites and pipes, and exogranitic stockwork and fissure veins, and replacement bodies. A common factor to all these deposits is the inherent greisen environment, characterised by postmagmatic metasomatic alteration and mineral deposition. Common alteration mineral assemblages include albite, quartz, muscovite, tourmaline, and fluorite ∓ topaz. Ore mineral assemblages commonly display a paragenetic sequence of oxides (cassiterite, wolframite, scheelite), followed by sulphides (molybdenite, pyrite, pyrrhotite, chalcopyrite sphalerite, arsenopyrite/loëllingite, Pb-Bi(Ag) sulphosalts) and then lower temperature carbonates (calcite, siderite, ankerite). Analysis of Pan African orogenic provinces in southern Africa (Damara and Saldanian Provinces) shows there is good potential for applying integrated exploration techniques in search of endo-exogreisen Sn-W systems. Careful analysis and interpretation of granitoid geochemistry (K₂0, Na₂0, FeO/Fe₂0₃, F, B, Sn, W, Mo, Cu, Rb, Sr, Ti, Zr) should aid delineation of Sn-W and Mo-Cu metallogenic provinces in these regions. Magnetic susceptibility determinations should also aid distinction of S-type ilmenite series (less than 1 x lO⁻⁴emu/g ) from I-type magnetite series (more than 1 x lO⁻⁴emu/g ) granitoids
- Full Text:
- Date Issued: 1985
Haleluya Haleluya
- Participants of Jouberton Workshop, Sethare, Richard, Dargie, Dave
- Authors: Participants of Jouberton Workshop , Sethare, Richard , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Jouberton f-sa
- Language: Setswana
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/295344 , vital:57325 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD091-30
- Description: Participants at Jouberton workshop perform own composition with Marimba accompaniment.
- Full Text: false
- Date Issued: 1985
- Authors: Participants of Jouberton Workshop , Sethare, Richard , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Jouberton f-sa
- Language: Setswana
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/295344 , vital:57325 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD091-30
- Description: Participants at Jouberton workshop perform own composition with Marimba accompaniment.
- Full Text: false
- Date Issued: 1985
Hambani niyokuzenza abafundi zonk'intlanga
- Zionists, Composer not specified, Dargie, Dave
- Authors: Zionists , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa City not specified f-sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/297522 , vital:57588 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD095-22
- Description: Zionist Church music.
- Full Text: false
- Date Issued: 1985
- Authors: Zionists , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa City not specified f-sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/297522 , vital:57588 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD095-22
- Description: Zionist Church music.
- Full Text: false
- Date Issued: 1985
He wena Botha
- Group of Boys, Composer not specified, Dargie, Dave
- Authors: Group of Boys , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Dashe f-sa
- Language: Xhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/295027 , vital:57282 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD090-19
- Description: Group of young people perform traditional Umtshotsho Dance Song.
- Full Text: false
- Date Issued: 1985
- Authors: Group of Boys , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Dashe f-sa
- Language: Xhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/295027 , vital:57282 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD090-19
- Description: Group of young people perform traditional Umtshotsho Dance Song.
- Full Text: false
- Date Issued: 1985
High performance liquid chromatographic analysis of erythromycin in serum and urine
- Authors: Stubbs, Christopher
- Date: 1985 , 2013-03-13
- Subjects: High performance liquid chromatography , Erythromycin , Erythromycin -- Pharmacokinetics , Chromatographic analysis
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3813 , http://hdl.handle.net/10962/d1004581 , High performance liquid chromatography , Erythromycin , Erythromycin -- Pharmacokinetics , Chromatographic analysis
- Description: Erythromycin, a macrolide antibiotic used mainly against gram-positive bacteria has been in clinical use since 1952 (1). Previous pharmacokinetic data published on this antibiotic have been derived predominantly from microbiological assay techniques. However, these techniques are relatively imprecise as well as being non-specific and extremely tedious to perform. A novel high performance liquid chromatographic analysis of erythromycin in human serum and urine using U.V. detection at 200 nm and/or electrochemical detection using both an amperometric and a coulometric electrochemical detector is presented. The method involves a solid phase extraction procedure followed by a simple phase separation step and chromatography on a reverse phase column. In order to select the optimum U.V. detector for this analysis, five "state of the art" detectors were compared in terms of their signal-to-noise ratios at U.V. wavelengths between 200 and 210 nm. A known metabolite des-N-methylerythromycin is readily detectable using U.V. detection, whilst another metabolite/degradation product anhydroerythromycin is not seen using U.V. detection but is readily observable using an electrochemical detector. The method has a limit of sensitivity of 0.25 μg/mL and 1.00 μg/mL in serum and urine respectively (U.V. detection) and is sufficiently sensitive to monitor serum and urine concentrations of erythromycin in man after administration of a single 500 mg erythromycin stearate tablet. , KMBT_363 , Adobe Acrobat 9.53 Paper Capture Plug-in
- Full Text:
- Date Issued: 1985
- Authors: Stubbs, Christopher
- Date: 1985 , 2013-03-13
- Subjects: High performance liquid chromatography , Erythromycin , Erythromycin -- Pharmacokinetics , Chromatographic analysis
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3813 , http://hdl.handle.net/10962/d1004581 , High performance liquid chromatography , Erythromycin , Erythromycin -- Pharmacokinetics , Chromatographic analysis
- Description: Erythromycin, a macrolide antibiotic used mainly against gram-positive bacteria has been in clinical use since 1952 (1). Previous pharmacokinetic data published on this antibiotic have been derived predominantly from microbiological assay techniques. However, these techniques are relatively imprecise as well as being non-specific and extremely tedious to perform. A novel high performance liquid chromatographic analysis of erythromycin in human serum and urine using U.V. detection at 200 nm and/or electrochemical detection using both an amperometric and a coulometric electrochemical detector is presented. The method involves a solid phase extraction procedure followed by a simple phase separation step and chromatography on a reverse phase column. In order to select the optimum U.V. detector for this analysis, five "state of the art" detectors were compared in terms of their signal-to-noise ratios at U.V. wavelengths between 200 and 210 nm. A known metabolite des-N-methylerythromycin is readily detectable using U.V. detection, whilst another metabolite/degradation product anhydroerythromycin is not seen using U.V. detection but is readily observable using an electrochemical detector. The method has a limit of sensitivity of 0.25 μg/mL and 1.00 μg/mL in serum and urine respectively (U.V. detection) and is sufficiently sensitive to monitor serum and urine concentrations of erythromycin in man after administration of a single 500 mg erythromycin stearate tablet. , KMBT_363 , Adobe Acrobat 9.53 Paper Capture Plug-in
- Full Text:
- Date Issued: 1985
Hlala kuMoya
- Zionists, Composer not specified, Dargie, Dave
- Authors: Zionists , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa City not specified f-sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/297491 , vital:57585 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD095-19
- Description: Zionist Church music.
- Full Text: false
- Date Issued: 1985
- Authors: Zionists , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa City not specified f-sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/297491 , vital:57585 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD095-19
- Description: Zionist Church music.
- Full Text: false
- Date Issued: 1985
Hosana
- Zingisa Seminary Congregation, Composer not specified, Dargie, Dave
- Authors: Zingisa Seminary Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Umtata sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/416242 , vital:71331 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC146b-14
- Description: Catholic mass hymn, accompanied by the marimba and clapping.
- Full Text: false
- Date Issued: 1985
- Authors: Zingisa Seminary Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Umtata sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/416242 , vital:71331 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC146b-14
- Description: Catholic mass hymn, accompanied by the marimba and clapping.
- Full Text: false
- Date Issued: 1985
Hosannah
- Zingisa Seminary Congregation, Composer not specified, Dargie, Dave
- Authors: Zingisa Seminary Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Umtata sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/416251 , vital:71332 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC146b-15
- Description: Catholic mass hymn, accompanied by the marimba.
- Full Text: false
- Date Issued: 1985
- Authors: Zingisa Seminary Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Umtata sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/416251 , vital:71332 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC146b-15
- Description: Catholic mass hymn, accompanied by the marimba.
- Full Text: false
- Date Issued: 1985
Hosannah, Alleluia
- Zola Church Congregation, Composer not specified, Dargie, Dave
- Authors: Zola Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Johannesburg sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/418230 , vital:71523 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC152a-08
- Description: Catholic mass hymn, accompanied by clapping.
- Full Text: false
- Date Issued: 1985
- Authors: Zola Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Johannesburg sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/418230 , vital:71523 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC152a-08
- Description: Catholic mass hymn, accompanied by clapping.
- Full Text: false
- Date Issued: 1985
Hozana makabongwe
- Zionists, Composer not specified, Dargie, Dave
- Authors: Zionists , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa City not specified f-sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/298104 , vital:57665 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD097-20
- Description: Religious music.
- Full Text: false
- Date Issued: 1985
- Authors: Zionists , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa City not specified f-sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/298104 , vital:57665 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD097-20
- Description: Religious music.
- Full Text: false
- Date Issued: 1985
IDindala
- Performer not specified, Composer Not Specified, Dargie, Dave
- Authors: Performer not specified , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Dashe sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/${Handle} , vital:60853 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC292a-07
- Description: Traditional Xhosa girls' initiation song sung by the women when fetching the idindala - the man who is to supervise the initiation ceremony
- Full Text: false
- Date Issued: 1985
- Authors: Performer not specified , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Dashe sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/${Handle} , vital:60853 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC292a-07
- Description: Traditional Xhosa girls' initiation song sung by the women when fetching the idindala - the man who is to supervise the initiation ceremony
- Full Text: false
- Date Issued: 1985
Igazi Lemvana
- Jouberton Choir, Composer Not Specified, Dargie, Dave
- Authors: Jouberton Choir , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Jouberton f-sa
- Language: isiXhosa , Zulu
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/296598 , vital:57471 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD093-31
- Description: Unaccompanied Sunday Mass Hymn.
- Full Text: false
- Date Issued: 1985
- Authors: Jouberton Choir , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Jouberton f-sa
- Language: isiXhosa , Zulu
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/296598 , vital:57471 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD093-31
- Description: Unaccompanied Sunday Mass Hymn.
- Full Text: false
- Date Issued: 1985
Igazi Lemvana
- Lumko Church Congregation, Composer not specified, Dargie, Dave
- Authors: Lumko Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Lumko sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/415770 , vital:71286 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC145-07
- Description: Instrumental Catholic hymn in celebration of Dick's Silver Jubilee of priesthood.
- Full Text: false
- Date Issued: 1985
- Authors: Lumko Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Lumko sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/415770 , vital:71286 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC145-07
- Description: Instrumental Catholic hymn in celebration of Dick's Silver Jubilee of priesthood.
- Full Text: false
- Date Issued: 1985
Igazi lemvana
- Lumko Church Congregation, Composer not specified, Dargie, Dave
- Authors: Lumko Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Lumko sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/415714 , vital:71280 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC145-01
- Description: Catholic hymn in celebration of Dick's Silver Jubilee of priesthood with drum accompaniment.
- Full Text: false
- Date Issued: 1985
- Authors: Lumko Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Lumko sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/415714 , vital:71280 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC145-01
- Description: Catholic hymn in celebration of Dick's Silver Jubilee of priesthood with drum accompaniment.
- Full Text: false
- Date Issued: 1985
Igazi Lemvana = The Blood of the Lamb
- Zingisa Seminary Congregation, Composer not specified, Dargie, Dave
- Authors: Zingisa Seminary Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Umtata sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/416202 , vital:71327 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC146b-10
- Description: Catholic mass hymn, accompanied by the marimba.
- Full Text: false
- Date Issued: 1985
- Authors: Zingisa Seminary Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Umtata sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/416202 , vital:71327 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC146b-10
- Description: Catholic mass hymn, accompanied by the marimba.
- Full Text: false
- Date Issued: 1985
Iingoma zama Gqoboka
- Ngqoko Village locals, Composer Not Specified, Dargie, Dave
- Authors: Ngqoko Village locals , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Ngqoko Village sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/319735 , vital:60215 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD150A-08
- Description: Traditional Xhosa song for special occasions with clapping accompaniment
- Full Text: false
- Date Issued: 1985
- Authors: Ngqoko Village locals , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Ngqoko Village sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/319735 , vital:60215 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD150A-08
- Description: Traditional Xhosa song for special occasions with clapping accompaniment
- Full Text: false
- Date Issued: 1985
Ilizwi leNkosi yethu liyakuma ngonaphakade
- Zingisa Seminary Congregation, Composer not specified, Dargie, Dave
- Authors: Zingisa Seminary Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Umtata sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/415956 , vital:71303 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC146a-07
- Description: Catholic mass hymn, accompanied by the marimba.
- Full Text: false
- Date Issued: 1985
- Authors: Zingisa Seminary Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Umtata sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/415956 , vital:71303 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC146a-07
- Description: Catholic mass hymn, accompanied by the marimba.
- Full Text: false
- Date Issued: 1985
Influence of endogenous female sex-steroids on mutagen metabolism
- Authors: Goold, Richard David
- Date: 1985 , 2013-03-15
- Subjects: Mutagenesis , Drugs -- Metabolism , Steroid hormones -- Receptors , Cytochrome P-450
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3819 , http://hdl.handle.net/10962/d1004919 , Mutagenesis , Drugs -- Metabolism , Steroid hormones -- Receptors , Cytochrome P-450
- Description: Cytochrome P-450, the terminal oxidase of the metabolic mono-oxygenase system, is thought to exist in multiple forms, which have differing substrate specificities, and are variably inducible by different enzyme inducers. Many mutagens, themselves unreactive, require metabolic activation by one or more of these cytochrome P-450-dependent microsomal enzymes for mutagenic activity. Such mutagens may be detected in the Salmonella mutagenicity test only by the incorporation of an hepatic microsomal (59) fraction into the assay (as a first approximation to in vivo metabolism). Induction of the microsomal enzymes by different agents enhances the metabolic activation of mutagens; in fact, many mutagens are only detected when the 59 fraction has been induced by appropriate agents. Inducers of the phenobarbital-type are known to enhance microsomal steroid hydroxylation when administered at supraphysiological levels, inducers of several mono-oxygenase activities. In turn, the steroids, have been reported to be The inductive effects of the female sex-steroids and the combined effects of steroid and phenobarbital (PB) pretreatment on the metabolic activation of four mutagens have been investigated using the Salmonella assay. Female Sprague-Dawley rats were pret reated with 17a-oestradiol (E2) or progesterone (PRG) , at a level of either 1 mg/kg or 20 mg / kg daily for 14 days. A duplicate set of similarly pretreated groups were also induced with PB. Hepatic microsomal fractions were prepared from each group and incubated with each of the te st mutagens in the presence of a tester strain known to detect each particular type of mutagen. Induction of the hepatic metabolizing system by PB increased the activation of the mutagens significantly (as reflected by an increased number of revertant prototrophic S .typhimurium colonies). The administration of PRG also caused significant, and dose-dependent, induction of the activation of af l atoxin B1, benzo(a)pyrene, and dimethylnitrosamine. In general, E2 exhibited no inductive effect, but it did produce an increase in the activation of aflatoxin B1 (a reaction which is known to be catalysed by a mono-oxygenase prefe rentially inducible by PB). When use was made of a microsomal fraction that was prepared from animals which were both steroidpretreated and induced by PB, mutagenic activation was of the same order of magnitude as that observed when induction was brought about by PB alone. The absence of additive effect, taken together with the observations already mentioned, indicate that steroids induce the same cytochrome isozymes that are induced by PB. The implications of sex-hormonal regulation of the metabolic activation of mutagens are briefly discussed. , KMBT_363 , Adobe Acrobat 9.53 Paper Capture Plug-in
- Full Text:
- Date Issued: 1985
- Authors: Goold, Richard David
- Date: 1985 , 2013-03-15
- Subjects: Mutagenesis , Drugs -- Metabolism , Steroid hormones -- Receptors , Cytochrome P-450
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3819 , http://hdl.handle.net/10962/d1004919 , Mutagenesis , Drugs -- Metabolism , Steroid hormones -- Receptors , Cytochrome P-450
- Description: Cytochrome P-450, the terminal oxidase of the metabolic mono-oxygenase system, is thought to exist in multiple forms, which have differing substrate specificities, and are variably inducible by different enzyme inducers. Many mutagens, themselves unreactive, require metabolic activation by one or more of these cytochrome P-450-dependent microsomal enzymes for mutagenic activity. Such mutagens may be detected in the Salmonella mutagenicity test only by the incorporation of an hepatic microsomal (59) fraction into the assay (as a first approximation to in vivo metabolism). Induction of the microsomal enzymes by different agents enhances the metabolic activation of mutagens; in fact, many mutagens are only detected when the 59 fraction has been induced by appropriate agents. Inducers of the phenobarbital-type are known to enhance microsomal steroid hydroxylation when administered at supraphysiological levels, inducers of several mono-oxygenase activities. In turn, the steroids, have been reported to be The inductive effects of the female sex-steroids and the combined effects of steroid and phenobarbital (PB) pretreatment on the metabolic activation of four mutagens have been investigated using the Salmonella assay. Female Sprague-Dawley rats were pret reated with 17a-oestradiol (E2) or progesterone (PRG) , at a level of either 1 mg/kg or 20 mg / kg daily for 14 days. A duplicate set of similarly pretreated groups were also induced with PB. Hepatic microsomal fractions were prepared from each group and incubated with each of the te st mutagens in the presence of a tester strain known to detect each particular type of mutagen. Induction of the hepatic metabolizing system by PB increased the activation of the mutagens significantly (as reflected by an increased number of revertant prototrophic S .typhimurium colonies). The administration of PRG also caused significant, and dose-dependent, induction of the activation of af l atoxin B1, benzo(a)pyrene, and dimethylnitrosamine. In general, E2 exhibited no inductive effect, but it did produce an increase in the activation of aflatoxin B1 (a reaction which is known to be catalysed by a mono-oxygenase prefe rentially inducible by PB). When use was made of a microsomal fraction that was prepared from animals which were both steroidpretreated and induced by PB, mutagenic activation was of the same order of magnitude as that observed when induction was brought about by PB alone. The absence of additive effect, taken together with the observations already mentioned, indicate that steroids induce the same cytochrome isozymes that are induced by PB. The implications of sex-hormonal regulation of the metabolic activation of mutagens are briefly discussed. , KMBT_363 , Adobe Acrobat 9.53 Paper Capture Plug-in
- Full Text:
- Date Issued: 1985
Inganzi Lemvana
- Christ the New Man Centre Congregation, Composer not specified, Dargie, Dave
- Authors: Christ the New Man Centre Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Garankuwa f-sa
- Language: Setswana
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/295729 , vital:57373 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD092-25
- Description: Sung mass at Christ the New Man Centre, GaRankuwa with drum accompaniment.
- Full Text: false
- Date Issued: 1985
- Authors: Christ the New Man Centre Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Garankuwa f-sa
- Language: Setswana
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/295729 , vital:57373 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD092-25
- Description: Sung mass at Christ the New Man Centre, GaRankuwa with drum accompaniment.
- Full Text: false
- Date Issued: 1985
Ingoma yentombe yabafana
- Mhlola, P, Composer Not Specified, Dargie, Dave
- Authors: Mhlola, P , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Ngqoko sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/320707 , vital:60367 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD151-04
- Description: Traditional Xhosa song with clapping accompaniment
- Full Text: false
- Date Issued: 1985
- Authors: Mhlola, P , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Ngqoko sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/320707 , vital:60367 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD151-04
- Description: Traditional Xhosa song with clapping accompaniment
- Full Text: false
- Date Issued: 1985