List of Titles

Molecular Detection of Antibiotic-Resistant Genes in Pseudomonas aeruginosa from Nonclinical Environment: Public Health Implications in Mthatha, Eastern Cape Province, South Africa

- Mojisola Clara Hosu, Sandeep Vasaikar, Grace Emily Okuthe, Teke Apalata

Authors: Mojisola Clara Hosu , Sandeep Vasaikar , Grace Emily Okuthe , Teke Apalata
Date: 5 January 2021
Subjects: Microbiology
Language: English
Type: Journal Article
Identifier: http://hdl.handle.net/11260/2417 , vital:41877
Description: Evaluation of resistant profiles and detection of antimicrobial-resistant genes of bacterial pathogens in the nonclinical milieu is imperative to assess the probable risk of dissemination of resistant genes in the environment. .is paper sought to identify antibiotic-resistant genes in Pseudomonas aeruginosa from nonclinical sources in Mthatha, Eastern Cape, and evaluate its public health implications. Samples collected from abattoir wastewater and aquatic environment were processed by membrane filtration and cultured on CHROMagarTM Pseudomonas medium. Species identification was performed by autoSCAN-4 (Dade Behring Inc., IL). Molecular characterization of the isolates was confirmed using real-time polymerase chain reaction (rPCR) and selected isolates were further screened for the possibility of harboring antimicrobial resistance genes. Fifty-one Pseudomonas species were recovered from abattoir wastewater and surface water samples, out of which thirty-six strains were Pseudomonas aeruginosa (70.6%). .e P. aeruginosa isolates demonstrated resistance to aztreonam (86.1%), ceftazidime (63.9%), piperacillin (58.3%), cefepime (55.6%), imipenem (50%), piperacillin/tazobactam (47.2%), meropenem (41.7%), and levofloxacin (30.6%). Twenty out of thirty-six P. aeruginosa displayed multidrug resistance profiles and were classified as multidrug-resistant (MDR) (55.6%). Most of the bacterial isolates exhibited a high Multiple Antibiotic Resistance (MAR) Index ranging from 0.08 to 0.69 with a mean MAR index of 0.38. In the rPCR analysis of fifteen P. aeruginosa isolates, 14 isolates (93.3%) were detected harboring blaSHV, six isolates (40%) harbored blaTEM, and three isolates (20%) harbored blaCTX-M, being the least occurring ESBL. Results of the current study revealed that P. aeruginosa isolates recovered from nonclinical milieu are resistant to frontline clinically relevant antipseudomonal drugs. .is is concerning as it poses a risk to the environment and constitutes a public health threat. Given the public health relevance, the paper recommends monitoring of multidrug-resistant pathogens in effluent environments.
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VIVA Comrade Moss

- NUMSA

Authors: NUMSA
Date: 25 April
Subjects: NUMSA
Language: English
Type: text
Identifier: http://hdl.handle.net/10962/109640 , vital:33163 , SALHA 14b : NUMSA
Description: The last 'Trial Update" reported on Comrade Moss’s case until mid-March. This report covers the period from that time up until 25th April.STADLER - "ANC EXPERT" Brigadier Stadler testified that the ANC had made certain calls to organisations within the country which, according to his "research", had been followed by organisations in the country. As examples he gave the ANC’s call for ungovernability, the formation of organs of people’s power and the destruction of town councils. During cross-examination Stadler conceded that he was not able to give examples of any direct link between the ANC and organisations inside the coutry but he said an inference could be drawn by looking at the ANC’s call and the behaviour of organisations inside the country.
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Date Issued: 25 April

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Morphology, histology and histochemistry of the digestive tract of the Banded tilapia, Tilapia sparrmanii (Perciformes: Cichlidae)

- Grace E. Okuthe, Bongile Bhomela

Authors: Grace E. Okuthe , Bongile Bhomela
Date: December 23, 2020
Subjects: Fish, gastrointestinal tract, histo-architecture
Language: English
Type: Journal Article
Identifier: http://hdl.handle.net/11260/2425 , vital:41881
Description: ABSTRACT. This study described anatomical, histological and histochemical features of the mucosal layer of the digestive tract of Tilapia sparrmanii Smith, 1840, an omnivorous freshwater fish endemic to Southern Africa. This species exhibited a short thick oesophagus with long deep longitudinal folds (466.68 ± 16.91 µm), and a thick (173.50 ± 10.92 µm) muscular layer that allow the passage of large food items. The mucosa was lined with stratified secretory epithelium rich in goblet cells that secreted neutral and acid mucins. The stomach was a sac-like structure with simple tubular glands surrounded by connective tissue. The mucosa was lined with simple columnar epithelium and the lamina propria exhibited a well-developed layer of gastric glands that occupied the entire length of the cardio-fundic region. The stomach mucosa consisted of epithelial cells with intense neutral mucin secretion which protects against gastric juice. Neck cells of gastric glands synthesized neutral and acid mucins. The intestine was highly coiled and presented a complex pattern of transversal folds internally (villi). Villi length decreased progressively from the anterior to the posterior intestine (p < 0.0001). Tunica muscularis of the mid-intestine had the thinnest thickness among all parts of the intestine (p < 0.0001). Goblet cells whose numbers increased towards the rectum secreted both acid and neutral mucins. The results indicate structural similarities of T. sparrmanii GIT with other tilapia species and will be useful for understanding the physiology of the digestive systems as well as functional components of the GIT.
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The prevalence of insufficient iodine intake in pregnancy in Africa: Protocol for a systematic review and meta-analysis

- Charles Bitamazire Businge, Benjamin Longo-Mbenza, Andre Pascal Kengne

Authors: Charles Bitamazire Businge , Benjamin Longo-Mbenza , Andre Pascal Kengne
Date: 22-8-2019
Language: English
Type: text , article
Identifier: http://hdl.handle.net/11260/3387 , vital:43338 , https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-019-1092-7#citeas
Description: Background: Insufficient iodine intake in pregnancy is associated with many adverse pregnancy outcomes. About 90% of African countries are at risk of iodine deficiency due to poor soils and dietary goitrogens. Pregnancy predisposes to insufficient iodine nutrition secondary to increased physiological demand and increased renal loss. Iodine deficiency is re-emerging in countries thought to be replete with pregnant women being the most affected. This review seeks to identify the degree of iodine nutrition in pregnancy on the entire African continent before and after the implementation of national iodization programmes. Methods: A systematic search of published literature will be conducted for observational studies that directly determined the prevalence of insufficient iodine intake among pregnant women in Africa. Electronic databases and grey literature will be searched for baseline data before the implementation of population-based iodine supplementation and for follow-up data up to December 2018. Screening of identified articles and data extraction will be conducted independently by two investigators. Risk of bias and methodological quality of the included studies will be assessed using a risk of bias tool. Appropriate meta-analytic techniques will be used to pool prevalence estimates from studies with similar features, overall and by major characteristics including the region of the study, time period (before and after implementation of iodization programmes), sample size and age. Heterogeneity of the estimates across studies will be quantified and publication bias investigated. This protocol is reported according to Preferred Reporting Items for Systematic reviews and Meta-Analysis protocols (PRISMA-P) 2015 guidelines. Discussion This review will help ascertain the impact of national iodization programmes on the iodine nutrition status in pregnancy in Africa and advise policy on the necessity for monitoring and mitigating iodine deficiency in pregnancy in Africa. This review is part of a thesis that will be submitted to the Faculty of Health Sciences, University of Cape Town, for the award of a PhD in Medicine whose protocol has been granted ethics approval (UCT HREC 135/2018). In addition, the results will be published in a peer-reviewed journal.
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Date Issued: 22-8-2019

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Digital finance and poverty in selected Sub-Saharan Countries

- Dube, Ziphozethu https://orcid.org/0000-0003-4532-5346

Authors: Dube, Ziphozethu https://orcid.org/0000-0003-4532-5346
Date: 2022-10
Subjects: Electronic funds transfers , Transmission mechanism (Monetary policy)
Language: English
Type: Doctoral theses , text
Identifier: http://hdl.handle.net/10353/23347 , vital:57616
Description: Since the 21st century, digital finance has emerged as a critical enabler and an excellent tool for meeting the UN 2030 Sustainable Development Goals (SDGs) through increasing financial inclusion and poverty reduction. The objective of achieving universal financial access by 2030 has led to recognising that financial inclusion has a significant role in economic growth and poverty eradication. The literature demonstrates that access to finance can affect poverty through access to credit, enabling savings, thereby facilitating intertemporal consumption smoothing. Digital finance is key to unlocking financial inclusion, particularly in developing countries. Building capacity in digital payments is one of the best ways to ensure a faster, better, and more cost-effective way to access financial services. The gender gap in developing countries states that (59% of men were reported to have a bank account in 2014, while 50% of women only had a bank account). Some groups, including women and the rural poor, are financially excluded compared to others. This study applied panel data regression analysis and structural equation modelling to investigate the nature of digital finance, its relationship with poverty and the transmission mechanism from digital finance to poverty in selected Sub-Saharan Countries. The results indicate that remittance is one of the most significant determinants of the use of digital finance in the Sub-Saharan region compared to other determinants of use for digital finance. Regarding the transmission mechanism between digital finance and poverty, the path analysis results suggest that the channel for remittance in the transmission mechanism has a more substantial impact on reducing poverty than savings in the Sub-Saharan region. The study recommends that remittance is essential, but savings are not critical in this digital age. This study contributed to literature by identifying the transmission mechanism between digital finance and poverty. This is beneficial to researchers and policymakers . It provides policy practitioners with a reference point on a model to build upon towards providing solutions to the problem, Sub-Saharan Countries encounter on delivering sustainable and broad-based economic growth. The study concludes by proposing that digital finance, particularly mobile money presents an excellent opportunity to increase access to finance and reduce poverty. , Thesis (PhD) -- Faculty of Management and Commerce, 2022
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Date Issued: 2022-10

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Land expropriation without compensation: a study of constructions of the Parliamentary process in selected mainstream and “ground-up” media from 27 February – 12 August 2018

- Jacobs, Luzuko G

Authors: Jacobs, Luzuko G
Date: 2022-10
Subjects: Discourse analysis , Communication Political aspects South Africa , Land reform Press coverage South Africa , Land reform Government policy South Africa , Communication in mass media , Frames (Sociology) South Africa , Journalism Political aspects South Africa , Moneyweb Holdings Ltd. , City Press (South Africa) , Afriforum (South Africa)‎ , African Farmers’ Association of South Africa (AFASA)‎
Language: English
Type: Academic theses , Doctoral theses , text
Identifier: http://hdl.handle.net/10962/297807 , vital:57630 , DOI 10.21504/10962/297807
Description: This study investigates the constructions of land expropriation without compensation (LEwC) in the discourses of two mainstream media, Moneyweb and City Press, and two ground-up platforms, Afriforum and the African Farmers’ Association of South Africa (AFASA). It follows the February 2018 adoption by Parliament, of LEwC as a policy to reorder the country’s unequal and racially bifurcated economy. The motivations for, and opposition to the policy locate land as ‘the issue’ in conquest and capitalism. How land is signified therefore, is important to the understandings of ‘restitution’ and/or ‘resolution’. The news platforms selected here are diverse: Moneyweb focuses on investments. City Press concerns itself with politics. Afriforum and AFASA are alternative sphericules linked to ethnically- polarised quotidian concerns with land as a key focus. Discourses are central to how citizens see and construct themselves and one another as subjects. As such, media frames can be connected to justice and inter-‘race’ complexities. This is a study of media influences in cultivating certain meanings and understandings of tenuous and fractious political situations characterised by inequality and interracial enmity. The thesis draws from the Epistemologies of the South as well as Marxism to constitute the locus of its enunciation of colonisation, liberal capitalism, land question, justice, ideology, discourse, and framing. This framework is geared towards emic understanding of interrelated local and global contexts of the land question. Conceptual clarity is key to the development of an emancipatory imagination. Qualitative framing analysis and critical discourse analysis are used in this study to examine a diachronic corpus of 124 articles from the four platforms covering 167-days, from the adoption of the LEwC motion through the initial round of public hearings. The findings suggest a strong influence of the structures of coloniality in discourses across a wide political spectrum. The frames and counter-frames in the four platforms are simultaneously divergent and similar. Some are reactionary and conservative, others are liberal-transformational and even radical-prefigurative. All however, orbit around abyssal, North-centric, liberal capitalist normativity as the centripetal centre. The study proposes rethinking of the land question, a radical exorcism from land discourses, of structures of coloniality of power, knowledge, and being. Their mobilisation, predominance and naturalisation in political communication is anti-transformation and helps keep Black South Africans to this day, under the heavy yoke of an oppressive colonial and Apartheid reality as perpetual economic slaves. , Thesis (PhD) -- Faculty of Humanities, Journalism and Media Studies, 2022
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Date Issued: 2022-10

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Analysis of early-phase contact tracing during the coronavirus disease 2019 outbreak in Mangaung Metro, Free State

- Monyobo, Priscilla Kesaletseng

Authors: Monyobo, Priscilla Kesaletseng
Date: 2022-09
Subjects: COVID-19 (Disease) , Contact tracing (Epidemiology) , Public health
Language: English
Type: Master's theses , text
Identifier: http://hdl.handle.net/10353/23533 , vital:58105
Description: Background and Aim Contact tracing is a critical public health measure for controlling and preventing the spread of infectious diseases. Although the principles underlying this strategy are not novel, understanding the changes in infectiousness of COVID-19 is indeed novel. As are the capacity and operating procedures required to support disease investigation in Mangang Metro during the SARS-CoV-2 (COVID-19) pandemic. On 16 March 2020, the first coronavirus disease case in the area, which led to a larger outbreak, occurred in Mangaung Metro, Free State province, South Africa. To date, Mangaung Metro remains the epicentre of the COVID-19 pandemic and the primary driver of the caseload in the Free State province. The aim of this study was to analyse contact tracing data in Mangaung Metro during the early phase of the COVID-19 outbreak (16 March 2020 – 30 June 2020) in order to measure the viral transmissibility of COVID-19 in the early stages of the outbreak, specifically in the context of Mangaung Metro. Methods A descriptive systematic analysis of index COVID-19 cases and their contacts in Mangaung Metro was conducted. The review period ran from 16 March to 30 June 2020, during which there was a total of 1 001 cases in Mangaung Metro. Data was captured on an Excel spreadsheet using the contact line list variables from the established National Institute of Communicable Disease contact line list framework. The inferential statistics were based on a time series analysis to compare the impact of contact tracing stratified by symptomatology and the root cause of the cases to the overall cases in Mangaung Metro. The study determined whether isolation, quarantine, and contact tracing were able to control outbreaks in the early phase using characteristics of disease transmission and parameters particularised to the COVID- 19 pathogen. Results As of 30 June 2020, the Free State province had a total of 2 072 COVID-19 cases. Mangaung Metro contributed 1 001 cases (48percent) of the total number of cases in the study period. Between March and June 2020, 3 553 contacts were traced in Mangaung Metro. This number translates to at least three investigated and traced contacts per index or laboratory confirmed positive case. From the traced contacts, 1 080 samples were collected and sent for laboratory testing. In April 2020, the greatest number of samples were collected. This high rate in sample collection is posited to be the result of the high rate of contacts traced, as well as the initial clinical guidelines followed for contact tracing. Most positive contacts were discovered in March 2020. One of the possible reasons for the high detection of COVID-19 confirmed positive contacts during the early stages of the outbreak was the focus and importance of contact tracing while the caseload remained relatively low. However, as the outbreak progressed in the Mangaung Metro context, the number and relative percentage of positive cases detected through contact tracing decreased. In total, the positive contacts recorded in March 2020 amounted to 92 (51.3percent), 18 in April (10.5percent), 41 in May (22.9percent), and 28 in June (15.6percent). The March 2020 tracking rate was the highest at 73.2percent, with an average contact tracing rate of 15.5percentby the end of June 2020. Of all the contacts traced, 7.9percent involved healthcare workers in the Free State. Conclusion The study’s findings show that contact tracing was an effective control measure during the early stages of the COVID-19 outbreak in Mangung Metro district. Furthermore, the impact was greatest when the caseload was low and the burden on the healthcare system less severe. Mangaung Metro demonstrated the capability of tracing more contacts in the early-early phase of the outbreak; however, as the outbreak progressed to the latent early phase, the caseload increased and fewer contacts were traced. The consequence of contact tracing not being as effective during the latent early phase relates to the increase in both exposed and untraceable contacts, which in turn fueled the increase of new cases. This further impacted the at-risk and vulnerable population, especially the elderly, who were at an increased risk if not traced in a timely manner, possibly resulting in mortality. , Thesis (MPH) -- Faculty of Health Sciences, 2022
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Date Issued: 2022-09

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Clinical governance implementation challenges in the Department of Health, Mpumalanga, South Africa

- Maduna, Patrick Hawkins https://orcid.org/0000-0002-4926-1661

Authors: Maduna, Patrick Hawkins https://orcid.org/0000-0002-4926-1661
Date: 2022-09
Subjects: Clinical competence , Evidence-based medicine , Health services administration
Language: English
Type: Doctoral theses , text
Identifier: http://hdl.handle.net/10353/23600 , vital:58194
Description: Clinical governance (CG) is the system through which health authorities are accountable for continuously improving the quality of their services and safeguarding high standards of care by creating an environment in which clinical excellence flourishes. South Africa is one of the countries where CG has not been successfully implemented. This study sought to explore the CG implementation challenges in the Mpumalanga province, South Africa. The study objectives included the seven pillars of CG. The study was a qualitative and exploratory, using purposive sampling technique to select study participants. A total of twenty-two (22) individuals were selected for the study. Semi-structured interviews were used for data collection. Each interview was transcribed verbatim by the researcher. Confidentiality was ensured through the coding of interviewee names. The content analysis technique was used for data analysis, using the study objectives as themes. The study found general lack of understanding of the concept of CG, poor performance of clinical audits, sub-standard clinical performance and effectiveness, poor clinical risk management, poor patient and public involvement in patient care, lack of evidence-based practice and research, inadequate training and development of healthcare workers, and sub-standard health information management across the department. The researcher recommends that the CG policy be prioritised by the Mpumalanga DOH, that systems be put in place to facilitate policy implementation, and that the departmental staff establishments at all levels, prioritise healthcare professionals in key leadership positions. In conclusion, there are numerous challenges that confront the Mpumalanga Department of Health regarding the implementation of clinical governance, requiring urgent attention. , Thesis (PhD) -- Faculty of Health Sciences, 2022
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Date Issued: 2022-09

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Implementation of constitutional values and principles in Cecelia Makiwane Hospital in the Eastern Cape Province

- Sigcau, Aviwe https://orcid.org/0000-0002-7409-8544

Authors: Sigcau, Aviwe https://orcid.org/0000-0002-7409-8544
Date: 2022-07
Subjects: Hospitals--Administration , Health services administration--South Africa
Language: English
Type: Master'stheses , text
Identifier: http://hdl.handle.net/10353/23460 , vital:57736
Description: This study aims to assess the implementation of the constitutional values and principles at Cecilia Makiwane Hospital: promoting professional ethics, efficient, effective, and economical use of resources, fairness, transparency, response to the people’s needs, and good human resources. The Constitutional values and principles champion democratic service in South Africa. It also encourages good governance through hospital employees implementing the Constitutional values and principles. The literature review reveals that there is a gap in the Implementation of the Constitutional values and principles in the hospitals due to the following challenges: many patients are still experiencing violations of their constitutional rights, shortages of drugs in hospitals, lack of equipment, poor infrastructure, corruption, freezing of posts, understaffing. The objectives of the study were: to assess the leadership values at Cecilia Makiwane hospital and determine their alignment with section 195 of the Constitution, to determine the implementation of the constitutional values and principles enshrined in chapter 10 of the Constitution, to examine the working conditions of the hospital, to evaluate the service quality at Cecilia Makiwane hospital., and to recommend measures and strategies that can be implemented to promote efficiency, effectiveness and economical use of resources at Cecilia Makiwane hospital. The study found that the implementation of the constitutional values and principles at Cecilia Makiwane hospital is not satisfactory. The findings show unethical leadership practices, and they put their interests first above the public needs. Regarding good human resources practices, the staff lacks career growth development programs, while promotion opportunities are influenced by nepotism and favouritism. The study recommends that for the hospital to be aligned to the constitutional values and principles, they need to provide training and workshops on the Public Service Code of Conduct, employ social theory for both management and staff, adopt communication strategies and teamwork, improve service impartiality, equity, effective time management performances, collaborative teamwork, accountability, and transparency. , Thesis (MA) -- Faculty of Management and Commerce, 2022
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Date Issued: 2022-07

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Infant feeding knowledge, attitudes and practices of mothers in private health facilities in Alice town, Eastern Cape, South Africa

- Oyeniran, Aderonke Adepeju

Authors: Oyeniran, Aderonke Adepeju
Date: 2022-07
Subjects: Breastfeeding
Language: English
Type: Master's theses , text
Identifier: http://hdl.handle.net/10353/23556 , vital:58132
Description: Background and aim of the study: Within the global field of health education, it is generally accepted that the topic of breast-feeding is a crucial discussion due to its maternal, infant, and communal benefits. However, certain African countries, such as South Africa, experience certain challenges related to both predictive factors and maternal attitudes to breast-feeding. To improve public awareness and promote the implementation of breast-feeding, these factors should be investigated to highlight the importance of this practice among young mothers. Method: The study utilised a cross-sectional survey by means of a self-administered questionnaire, which was completed by the carefully chosen participants. The collected data were then analysed using a statistical package for social sciences (SPSS) (frequency, percentages, mean and standard deviation) and inferential statistics (logistic regression). The level of significance for the inferential statistics was set at 0.05. Results: A total of 377 infant mothers participated in the study with median age of 30. Most infant mothers that participated in the study were well educated with infant mother 189 having a bachelor’s degree. The findings revealed that mothers of 40 years above are 1.51 times more likely not to breastfeed exclusively compared to mothers of less than 40 years of age (95percent CI, 0.75-2.25). The odds ratio of the incidence of decision in breastfeeding for participants with breastfeeding and formula milk was 1.66 (95percent CI, 0.87-2.53). In term of family support, mothers who don’t receive family support were 3.43 times more likely no to breastfeed. The result also revealed that mothers with breast pain were 0.98 more likely not to breastfeed. Conclusion: This study concludes that infant mothers are well informed about breastfeeding. This study also revealed that factors such as infant mothers’ knowledge about breastfeeding, medical health of both mother and infant and cultural norms can go a long way in influencing the decision of mothers to breastfeeding their infant or not. , Thesis (MPH) -- Faculty of Health Sciences, 2022
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Date Issued: 2022-07

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Investigation of risky sexual behaviour amongst HIV/AIDS positive individuals on antiretroviral treatment in Buffalo City Metropolitan Municipality Eastern Cape Province, South Africa

- Pere, Mzukisi Ernest

Authors: Pere, Mzukisi Ernest
Date: 2022-07
Subjects: Sexual behaviour -- South Africa -- Eastern Cape , Youth Sexual behaviour
Language: English
Type: Master's theses , text
Identifier: http://hdl.handle.net/10353/23578 , vital:58190
Description: Background: Human immunodeficiency virus (HIV)/ acquired immune deficiency syndrome (AIDS) is one of the major public health concerns. Antiretroviral treatments (ART) is available immediately for HIV-positive individuals but sexually transmitted infections are on the rise. The majority of HIV positive patients on ART are engaging in unsafe sexual practices. Purpose: The aim of this study was to investigate risky sexual behaviour of people on antiretroviral treatment regarding prevention. The study was conducted on adult clients in the Buffalo City Metropolitan Municipality. Methods: A quantitative and descriptive cross-sectional design was conducted whereby 304 patients who visited Nontyatyambo Health Centre were randomly selected. Data was entered and analyzed using Statistical Package for the Social Sciences (SPSS) 24. Simple descriptive statistics such as numbers, percentages and tables were used to characterise variables. A chi-square test was used to explore associations between dependent and independent variables. Test significance, confidence intervals and p-values of all the causes and contributory factors were set at 0.05. Results: Thirty two percent reported having sex with multiple sexual partners while 19percent reported never using a condom. Forty eight percent reported having had sexually transmitted infections since starting on ART. The median age (36 years (IQR: 31, 45) vs. 35 years (IQR: 26, 40)) of those who reported STIs was higher than the median age of those who did not report STI (p=0.012). Males (57percent, p=0.049), those who were employed (55percent, p=0.048), and those who were cohabitating (68percent, 0.030) were more likely to report STI. Similarly, those who had unprotected sex with a casual partner (62percent, p<0.001), and those who did not use a condom because a partner did not like it (71percent, p=0.001) were more likely to report STIs. A significant number of 32percent of the participants reported engaging in risky sexual practices while 48percent had reported an STI. Recommendations include educational outreach programmes and capacitation of health care workers with appropriate skills and tools. , Thesis (MPH) -- Faculty of Health Sciences, 2022
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Date Issued: 2022-07

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