An appraisal of basic infrastructural service delivery and community participation at the local level a case study of three municipalities in the Eastern Cape
- Authors: Mamba, Bonginkosi
- Date: 2008
- Subjects: Municipal services -- South Africa -- Eastern Cape Case studies , Housing policy -- South Africa -- Eastern Cape Case studies , Housing -- South Africa -- Eastern Cape Case studies , Local government -- South Africa -- Eastern Cape Case studies
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:958 , http://hdl.handle.net/10962/d1002692 , Municipal services -- South Africa -- Eastern Cape Case studies , Housing policy -- South Africa -- Eastern Cape Case studies , Housing -- South Africa -- Eastern Cape Case studies , Local government -- South Africa -- Eastern Cape Case studies
- Description: Housing provision plays a vital role in meeting basic needs. Dwellings provide the security required for basic functioning and are thus essential for both human development and the alleviation of poverty. This study examines the levels and quality of basic infrastructural service delivery (electricity, water and sanitation) at local government level, focusing on housing. The local government areas studied include Grahamstown Fort Beaufort and Duncan Village. This was done for the purposes of analyzing the effectiveness of the existing housing policy with regard to the adequacy of scale, its developmental logic, implementation and coordination. Justification for basic infrastructural service delivery is based on the Basic Needs Approach [BNA] which forms the cornerstone of the World Bank’s delivery framework. The paper makes use of two methods: firstly, secondary sources are used to provide an impression of the broad policy framework focusing around basic service delivery with housing as the centrepiece. Specific attention is thus given to Integrated Development Plans (IDPs) as this is the level of policy-making responsible for the delivery of these services to communities. Secondly, previously un-analysed data drawn from a household social exclusion survey (2005-2006) conducted in three Eastern Cape municipalities (Buffalo City, Makana and Nkonkobe – representing respectively urban, small town, and rural areas) are evaluated. The data are analysed two ways – graphically and through a regression analysis – to test four hypotheses regarding basic service delivery. Graphical analysis demonstrates that services differ according to housing type and location. It was found that brick houses seem more likely to have better basic services than either shacks or mud dwellings. The results also show that there are inequalities in the provision of certain basic services such as water and sanitation between Duncan Village and Grahamstown. Overall, the results of this study show that government is still faced with major challenges in addressing housing backlogs.
- Full Text:
- Date Issued: 2008
- Authors: Mamba, Bonginkosi
- Date: 2008
- Subjects: Municipal services -- South Africa -- Eastern Cape Case studies , Housing policy -- South Africa -- Eastern Cape Case studies , Housing -- South Africa -- Eastern Cape Case studies , Local government -- South Africa -- Eastern Cape Case studies
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:958 , http://hdl.handle.net/10962/d1002692 , Municipal services -- South Africa -- Eastern Cape Case studies , Housing policy -- South Africa -- Eastern Cape Case studies , Housing -- South Africa -- Eastern Cape Case studies , Local government -- South Africa -- Eastern Cape Case studies
- Description: Housing provision plays a vital role in meeting basic needs. Dwellings provide the security required for basic functioning and are thus essential for both human development and the alleviation of poverty. This study examines the levels and quality of basic infrastructural service delivery (electricity, water and sanitation) at local government level, focusing on housing. The local government areas studied include Grahamstown Fort Beaufort and Duncan Village. This was done for the purposes of analyzing the effectiveness of the existing housing policy with regard to the adequacy of scale, its developmental logic, implementation and coordination. Justification for basic infrastructural service delivery is based on the Basic Needs Approach [BNA] which forms the cornerstone of the World Bank’s delivery framework. The paper makes use of two methods: firstly, secondary sources are used to provide an impression of the broad policy framework focusing around basic service delivery with housing as the centrepiece. Specific attention is thus given to Integrated Development Plans (IDPs) as this is the level of policy-making responsible for the delivery of these services to communities. Secondly, previously un-analysed data drawn from a household social exclusion survey (2005-2006) conducted in three Eastern Cape municipalities (Buffalo City, Makana and Nkonkobe – representing respectively urban, small town, and rural areas) are evaluated. The data are analysed two ways – graphically and through a regression analysis – to test four hypotheses regarding basic service delivery. Graphical analysis demonstrates that services differ according to housing type and location. It was found that brick houses seem more likely to have better basic services than either shacks or mud dwellings. The results also show that there are inequalities in the provision of certain basic services such as water and sanitation between Duncan Village and Grahamstown. Overall, the results of this study show that government is still faced with major challenges in addressing housing backlogs.
- Full Text:
- Date Issued: 2008
Evaluation of the pharmaceutical availability of erythromycin from topical formulations
- Authors: Mandimika, Nyaradzo
- Date: 2008
- Subjects: Pharmacy -- Research Chromatographic analysis Gel permeation chromatography Gels (Pharmacy) Chemistry, analytic Acne -- Treatment Sebaceous glands -- Diseases -- Treatment Drugs -- Testing Erythromycin -- Bioavailability
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:3771 , http://hdl.handle.net/10962/d1003249
- Description: Erythromycin (ERY) is a macrolide antibiotic which is used in the treatment of acne vulgaris.Acne is a common skin condition that occurs when the sebaceous glands and hair shafts become infected by the bacteria Propionibacterium acnes. Acne is a chronic condition that may last for years and the severity of the effects of the disease on patients is often undermined especially in third world countries where more emphasis is placed on other more life-threatening diseases. It may cause considerable physical and emotional distress to sufferers along with the possibility of permanent scarring. Although use of topical ERY formulations is not the first line of treatment it has proven to be effective in treating inflammation of skin and skin structures cause by the responsible bacteria. To-date there are a variety of vehicles which are used in preparing topical ERY formulations namely ointment and gel bases, alcoholic solutions and pledgets. All the gel formulations on the market contain hydroxypropyl cellulose, alcohol and water along with the active ingredient(s). However, some gel formulations contain propylene glycol in addition to these excipients an example being Emgel®. Propylene glycol has been shown to affect the penetration of topically applied drugs through the skin suggesting that it would be highly likely that those formulations which contain propylene glycol may release more ERY into the skin following application. With this in mind, two ERY gel formulations were produced which contained different percentages of propylene glycol. According to the FDA guidelines, pharmacokinetic measurements in blood, plasma and/or urine of topical dermatological drug products are not feasible to document bioequivalence since the active ingredient(s) in topical formulations is/are not intended to be absorbed into the systemic circulation and in addition, concentrations in extracutaneous biological tissues would generally not be measurable. This limits determination of bioavailability and assessment of bioequivalence of such products to pharmacodynamic measurements, clinical trials and dermatopharmacokinetic (DPK) measurements such as tape stripping (TS) and microdialysis (MD).TS is a sampling technique which involves sequential removal of layers of the stratum corneum using strips of adhesive tape. This technique has found increasing use in DPK studies for investigation of drug kinetics in the skin following the application of a topical formulation. The technique has also been used as a diagnostic tool in assessing the quality of the stratum corneum in diseased skin. In the current research study, the tape stripping technique was used to investigate the pharmaceutical/biological availability of topical gel formulations containing ERY. MD is another DPK sampling technique which has been used to determine the amount of a topically applied drug that penetrates through the stratum corneum to reach deeper tissues of the skin. The in vivo sampling technique involves the insertion of microdialysis probes beneath the skin surface in the dermal tissue and allows for real-time sampling of the analyte at its target site. Recently in vitro MD has also been successfully used to assess the pharmaceutical availability of a topical corticosteroid, mometesone furoate, from topical formulations. Based on this work, microdialysis was used to determine the pharmaceutical availability of ERY from gel formulations which were developed for use in this research. The results of the pharmaceutical availability of ERY from in vivo tape stripping studies and the in vitro microdialysis studies were compared to establish correlation between the data. Pharmaceutical equivalence and bioequivalence data obtained from the respective studies on the gel formulations were investigated by statistical analysis of the data generated from both the in vitro and in vivo experiments. In summary the objectives of this research were: 1. To develop and validate a high performance liquid chromatography method suitable to analyse ERY concentrations obtained from in vitro microdialysis studies and in vivo tape stripping studies. 2. To prepare two different ERY gel formulations with different percentage content of propylene glycol. 3. To determine the pharmaceutical availability of ERY from two different gel formulations using in vitro microdialysis. 4. To develop and validate a tape stripping technique which could be used to determine percutaneous penetration and bioequivalence of the gel formulations. 5. To compare in vitro microdialysis and in vivo tape stripping data and attempt to establish a correlation between the two different approaches.
- Full Text:
- Date Issued: 2008
- Authors: Mandimika, Nyaradzo
- Date: 2008
- Subjects: Pharmacy -- Research Chromatographic analysis Gel permeation chromatography Gels (Pharmacy) Chemistry, analytic Acne -- Treatment Sebaceous glands -- Diseases -- Treatment Drugs -- Testing Erythromycin -- Bioavailability
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:3771 , http://hdl.handle.net/10962/d1003249
- Description: Erythromycin (ERY) is a macrolide antibiotic which is used in the treatment of acne vulgaris.Acne is a common skin condition that occurs when the sebaceous glands and hair shafts become infected by the bacteria Propionibacterium acnes. Acne is a chronic condition that may last for years and the severity of the effects of the disease on patients is often undermined especially in third world countries where more emphasis is placed on other more life-threatening diseases. It may cause considerable physical and emotional distress to sufferers along with the possibility of permanent scarring. Although use of topical ERY formulations is not the first line of treatment it has proven to be effective in treating inflammation of skin and skin structures cause by the responsible bacteria. To-date there are a variety of vehicles which are used in preparing topical ERY formulations namely ointment and gel bases, alcoholic solutions and pledgets. All the gel formulations on the market contain hydroxypropyl cellulose, alcohol and water along with the active ingredient(s). However, some gel formulations contain propylene glycol in addition to these excipients an example being Emgel®. Propylene glycol has been shown to affect the penetration of topically applied drugs through the skin suggesting that it would be highly likely that those formulations which contain propylene glycol may release more ERY into the skin following application. With this in mind, two ERY gel formulations were produced which contained different percentages of propylene glycol. According to the FDA guidelines, pharmacokinetic measurements in blood, plasma and/or urine of topical dermatological drug products are not feasible to document bioequivalence since the active ingredient(s) in topical formulations is/are not intended to be absorbed into the systemic circulation and in addition, concentrations in extracutaneous biological tissues would generally not be measurable. This limits determination of bioavailability and assessment of bioequivalence of such products to pharmacodynamic measurements, clinical trials and dermatopharmacokinetic (DPK) measurements such as tape stripping (TS) and microdialysis (MD).TS is a sampling technique which involves sequential removal of layers of the stratum corneum using strips of adhesive tape. This technique has found increasing use in DPK studies for investigation of drug kinetics in the skin following the application of a topical formulation. The technique has also been used as a diagnostic tool in assessing the quality of the stratum corneum in diseased skin. In the current research study, the tape stripping technique was used to investigate the pharmaceutical/biological availability of topical gel formulations containing ERY. MD is another DPK sampling technique which has been used to determine the amount of a topically applied drug that penetrates through the stratum corneum to reach deeper tissues of the skin. The in vivo sampling technique involves the insertion of microdialysis probes beneath the skin surface in the dermal tissue and allows for real-time sampling of the analyte at its target site. Recently in vitro MD has also been successfully used to assess the pharmaceutical availability of a topical corticosteroid, mometesone furoate, from topical formulations. Based on this work, microdialysis was used to determine the pharmaceutical availability of ERY from gel formulations which were developed for use in this research. The results of the pharmaceutical availability of ERY from in vivo tape stripping studies and the in vitro microdialysis studies were compared to establish correlation between the data. Pharmaceutical equivalence and bioequivalence data obtained from the respective studies on the gel formulations were investigated by statistical analysis of the data generated from both the in vitro and in vivo experiments. In summary the objectives of this research were: 1. To develop and validate a high performance liquid chromatography method suitable to analyse ERY concentrations obtained from in vitro microdialysis studies and in vivo tape stripping studies. 2. To prepare two different ERY gel formulations with different percentage content of propylene glycol. 3. To determine the pharmaceutical availability of ERY from two different gel formulations using in vitro microdialysis. 4. To develop and validate a tape stripping technique which could be used to determine percutaneous penetration and bioequivalence of the gel formulations. 5. To compare in vitro microdialysis and in vivo tape stripping data and attempt to establish a correlation between the two different approaches.
- Full Text:
- Date Issued: 2008
International law before municipal courts: the role of International Court of Justice decisions in domestic court proceedings with specific reference to United States case examples
- Authors: Mangezi, Mutsa
- Date: 2008
- Subjects: International Court of Justice -- Cases Vienna Convention on Consular Relations (1963) International and municipal law -- United States -- Cases International law -- United States -- Cases Jurisdiction (International law) -- Cases
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:3711 , http://hdl.handle.net/10962/d1007325
- Description: In the case of LaGrand (Germany v United States), the International Court of Justice held that the United States (US) had violated its international obligation to Germany under the Vienna Convention on Consular Relations when it executed two German nationals without first informing them of their consular rights. The case came before the court after the United States had disregarded a preliminary ruling passed by the IC], which directed the US not to execute the German nationals pending the outcome of the ICJ case. The decision raised the issue of the effect of ICJ decisions in domestic proceedings and the effectiveness of ICJ enforcement mechanisms. This thesis considers the possibility of a role for national courts as active enforcers of ICJ decisions. It is argued that whilst evidence shows that there is no legal obligation on courts to enforce ICJ decisions, there is certainly room in international law to facilitate this development. In support of this argument, the thesis demonstrates how basic presuppositions about international law have shifted over the last few decades. This shift has been both the impetus and the result of globalisation. The case of LaGrand alongside similar cases is used to show how national courts may play an increased role in the enforcement of ICJ decisions.
- Full Text:
- Date Issued: 2008
- Authors: Mangezi, Mutsa
- Date: 2008
- Subjects: International Court of Justice -- Cases Vienna Convention on Consular Relations (1963) International and municipal law -- United States -- Cases International law -- United States -- Cases Jurisdiction (International law) -- Cases
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:3711 , http://hdl.handle.net/10962/d1007325
- Description: In the case of LaGrand (Germany v United States), the International Court of Justice held that the United States (US) had violated its international obligation to Germany under the Vienna Convention on Consular Relations when it executed two German nationals without first informing them of their consular rights. The case came before the court after the United States had disregarded a preliminary ruling passed by the IC], which directed the US not to execute the German nationals pending the outcome of the ICJ case. The decision raised the issue of the effect of ICJ decisions in domestic proceedings and the effectiveness of ICJ enforcement mechanisms. This thesis considers the possibility of a role for national courts as active enforcers of ICJ decisions. It is argued that whilst evidence shows that there is no legal obligation on courts to enforce ICJ decisions, there is certainly room in international law to facilitate this development. In support of this argument, the thesis demonstrates how basic presuppositions about international law have shifted over the last few decades. This shift has been both the impetus and the result of globalisation. The case of LaGrand alongside similar cases is used to show how national courts may play an increased role in the enforcement of ICJ decisions.
- Full Text:
- Date Issued: 2008
The effectiveness of blood donor education programmes in secondary schools in Mthatha (Eastern Cape)
- Authors: Manjezi, Miseka Elizabeth
- Date: 2008
- Subjects: Blood -- Transfusion -- Social aspects -- South Africa -- Eastern Cape , Blood donors -- South Africa -- Eastern Cape -- Attitudes
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8701 , http://hdl.handle.net/10948/1010 , Blood -- Transfusion -- Social aspects -- South Africa -- Eastern Cape , Blood donors -- South Africa -- Eastern Cape -- Attitudes
- Description: The dissertation takes the form of an impact study. It is based on a ten month period of research involving a literature review, interviews with headmasters of secondary schools who gave permission to survey their students, educational talks to secondary school learners and a survey of 500 learners from different schools in the Mthatha region. Purpose: The research endeavour addressed the problem of investigating the effectiveness of blood donor education in secondary schools in Mthatha region. Design/methodology/approach: This study employed a questionnaire-based survey. Five schools namely Mthatha High School, Holy Cross High School, Strategic High School; St Johns’ College and Zamukulungisa High School participated in this study. The Statistical Analysis System was employed to assess the association between the awareness strategies and general donor response. A chi–square test of association, based on the p –value approach, was used to achieve the results. Findings: This study finds that a blood donor education programme can increase blood donation awareness; benefit the schools and community, thus increasing the blood donor base. Receiving information as to the criteria for blood donation and how each individual donation is used to save a life is seen as a powerful means of reinforcement. Research limitations/implications: Further research is recommended on a large scale, involving all schools in Mthatha region. The research was delayed because it employed a new approach and a team had to be appointed before the blood donor centre can be opened. It is further recommended a once–off educational programme is not ideal because learners may not have received blood donation education before and should be repeated in follow-up sessions. Originality: This is the first research study looking at the effectiveness of a blood donor education programme in Mthatha secondary schools.
- Full Text:
- Date Issued: 2008
The effectiveness of blood donor education programmes in secondary schools in Mthatha (Eastern Cape)
- Authors: Manjezi, Miseka Elizabeth
- Date: 2008
- Subjects: Blood -- Transfusion -- Social aspects -- South Africa -- Eastern Cape , Blood donors -- South Africa -- Eastern Cape -- Attitudes
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8701 , http://hdl.handle.net/10948/1010 , Blood -- Transfusion -- Social aspects -- South Africa -- Eastern Cape , Blood donors -- South Africa -- Eastern Cape -- Attitudes
- Description: The dissertation takes the form of an impact study. It is based on a ten month period of research involving a literature review, interviews with headmasters of secondary schools who gave permission to survey their students, educational talks to secondary school learners and a survey of 500 learners from different schools in the Mthatha region. Purpose: The research endeavour addressed the problem of investigating the effectiveness of blood donor education in secondary schools in Mthatha region. Design/methodology/approach: This study employed a questionnaire-based survey. Five schools namely Mthatha High School, Holy Cross High School, Strategic High School; St Johns’ College and Zamukulungisa High School participated in this study. The Statistical Analysis System was employed to assess the association between the awareness strategies and general donor response. A chi–square test of association, based on the p –value approach, was used to achieve the results. Findings: This study finds that a blood donor education programme can increase blood donation awareness; benefit the schools and community, thus increasing the blood donor base. Receiving information as to the criteria for blood donation and how each individual donation is used to save a life is seen as a powerful means of reinforcement. Research limitations/implications: Further research is recommended on a large scale, involving all schools in Mthatha region. The research was delayed because it employed a new approach and a team had to be appointed before the blood donor centre can be opened. It is further recommended a once–off educational programme is not ideal because learners may not have received blood donation education before and should be repeated in follow-up sessions. Originality: This is the first research study looking at the effectiveness of a blood donor education programme in Mthatha secondary schools.
- Full Text:
- Date Issued: 2008
An investigation of the antimicrobial and antifouling properties of marine algal metabolites
- Authors: Mann, Maryssa Gudrun Ailsa
- Date: 2008 , 2013-07-11
- Subjects: Anti-infective agents , Marine metabolites -- Therapeutic use , Marine algae , Pharmacognosy , Fouling , Marine fouling organisms
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3831 , http://hdl.handle.net/10962/d1007465 , Anti-infective agents , Marine metabolites -- Therapeutic use , Marine algae , Pharmacognosy , Fouling , Marine fouling organisms
- Description: Prevention of the accumulation of undesirable biological material i.e. biofouling upon a solid surface requires the use of antifouling systems. The solid surface may be a contact lens, an off shore oil rig or a living organism. When chemicals are employed as a mechanism of defense against biofouling, the agents involved are known as antifouling agents. Marine algae must protect themselves from fouling organisms and it is thought that one of the mechanisms used by these organisms is the production of secondary metabolites with an array of biological activities. In vitro studies have shown numerous compounds isolated from marine algae to possess antibacterial, antifungal and antimacrofouling activity. The aim of this study was to evaluate the secondary metabolite extracts of selected Southern African marine macro-algae as a potential source of compounds that inhibit biofilm formation and that could be used as antifouling agents. In this project, marine macro-algae were collected from various sites along the South African coastline. Their extracts were screened for antimicrobial activity against four ubiquitous microorganisms, Staphylococcus aureus, Klebsiella pneumoniae, Mycobacterium aurm and Candida albicans. Results of screening assays guided the fractionation of two Rhodophyta, Plocamium corallorhiza and Laurencia flexuosa. The algae were fractionated using silica gel column chromatography and compounds were isolated by semi-preparative normal phase HPLC. Compound characterization was performed using UV, IR and advanced one- and two-dimensional NMR (¹H, ¹³C NMR, COSY, HSQC, HMBC and NOESY) spectroscopy and mass spectrometry. Ten halogenated monoterpenes including four members of the small class of halogenated monoterpene aldehydes were isolated from extracts of P. corallorhiza. The compounds isolated included the known compounds 3,4,6,7-tetrachloro-3,7-dimethyl-1-octene; 4,6-dibromo-1, 1-dichloro-3,7 -dimethyl-2E,7 octadiene; 4,8-d ibromo-1,1,7 -trichloro-3, 7-dimethyl-2,5Eoctadiene;1 ,4,8-tribromo-3, 7 -dichloro-3,7-dimethyl-1 E,5E-octadiene; 8-bremo-6, 7-dichloro-3,7-dimethyl-octa-2E,4E-dienal; 4-Bromo-8-chloro-3,7-dimethyl-octa-2E,6E-dienal; 4,6- Dibromo-3,7-dimethyl-octa-2E,7-dienal; 2,4-dichloro-1-(2-chlorovinyl)-1-methyl-5-methylidene-cyclohexane and two new metabolites 4,8-chloro-3,7-dimethyl-2Z,4,6Z-octatrien-1-al and Compound 3.47. Methodology was developed for the chemical derivatization and mass spectrometric analysis of the aldehydic compounds, The aldehyde trapping reagent 0-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine hydrochloride was used to derivatize the molecules, stabilizing them and allowing for their complete characterization. From Laurencia flexuosa a new cuparene sesquiterpene 4-bremo-2-(5-hydroxy-1,2,2- trimethylcyclopent-3-enyl)-5-methylphenol was isolated along with two geometric isomers of the vinyl acetylene bromofucin , An halogenated monoterpene 3S*,4R*-1-bromo-3,4,8-trichloro-9-dichloromethyl-1-E,5-E,7-Z-octatriene was also isolated but was suspected to be a contaminant and an investigation into its biological source revealed that it originated from Plocamium suhrii. A third alga, Martensia elegans was extracted based on published reports of antimicrobial compounds in related species. A new a-alkyl malate derivative was isolated and characterized. Selected compounds isolated during the course of the study were employed in preliminary assays that tested their ability to inhibit biofilm formation by Pseudomonas aeruginosa. The halogenated monoterpenes isolated from the Plocamium species were the only active compounds. 3S*,4R*-1-bromo-3,4,S-trichloro-g-dichloromethyl-1-E,5-E,7-octatriene from P. suhrii inhibited biofilm formation through antibacterial activity on planktonic cells but could not prevent biofilm formation when employed as a film on the surface of microtitre plate wells. 1,4,8-tribromo-3,7-dichloro-3,7-dimethyl-1E,5E-octadiene and 4,6-dibromo-1,1-dichloro-3,7-dimethyl-2E,7-octadiene inhibited biofilm formation when applied as a film to the microtitre plate wells but had no significant antibacterial activity. No potential antifouling agents were identified in this project but the antimicrobial activity exhibited by the crude algal extracts was highly encouraging and a number of new research areas have been identified. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
- Date Issued: 2008
- Authors: Mann, Maryssa Gudrun Ailsa
- Date: 2008 , 2013-07-11
- Subjects: Anti-infective agents , Marine metabolites -- Therapeutic use , Marine algae , Pharmacognosy , Fouling , Marine fouling organisms
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3831 , http://hdl.handle.net/10962/d1007465 , Anti-infective agents , Marine metabolites -- Therapeutic use , Marine algae , Pharmacognosy , Fouling , Marine fouling organisms
- Description: Prevention of the accumulation of undesirable biological material i.e. biofouling upon a solid surface requires the use of antifouling systems. The solid surface may be a contact lens, an off shore oil rig or a living organism. When chemicals are employed as a mechanism of defense against biofouling, the agents involved are known as antifouling agents. Marine algae must protect themselves from fouling organisms and it is thought that one of the mechanisms used by these organisms is the production of secondary metabolites with an array of biological activities. In vitro studies have shown numerous compounds isolated from marine algae to possess antibacterial, antifungal and antimacrofouling activity. The aim of this study was to evaluate the secondary metabolite extracts of selected Southern African marine macro-algae as a potential source of compounds that inhibit biofilm formation and that could be used as antifouling agents. In this project, marine macro-algae were collected from various sites along the South African coastline. Their extracts were screened for antimicrobial activity against four ubiquitous microorganisms, Staphylococcus aureus, Klebsiella pneumoniae, Mycobacterium aurm and Candida albicans. Results of screening assays guided the fractionation of two Rhodophyta, Plocamium corallorhiza and Laurencia flexuosa. The algae were fractionated using silica gel column chromatography and compounds were isolated by semi-preparative normal phase HPLC. Compound characterization was performed using UV, IR and advanced one- and two-dimensional NMR (¹H, ¹³C NMR, COSY, HSQC, HMBC and NOESY) spectroscopy and mass spectrometry. Ten halogenated monoterpenes including four members of the small class of halogenated monoterpene aldehydes were isolated from extracts of P. corallorhiza. The compounds isolated included the known compounds 3,4,6,7-tetrachloro-3,7-dimethyl-1-octene; 4,6-dibromo-1, 1-dichloro-3,7 -dimethyl-2E,7 octadiene; 4,8-d ibromo-1,1,7 -trichloro-3, 7-dimethyl-2,5Eoctadiene;1 ,4,8-tribromo-3, 7 -dichloro-3,7-dimethyl-1 E,5E-octadiene; 8-bremo-6, 7-dichloro-3,7-dimethyl-octa-2E,4E-dienal; 4-Bromo-8-chloro-3,7-dimethyl-octa-2E,6E-dienal; 4,6- Dibromo-3,7-dimethyl-octa-2E,7-dienal; 2,4-dichloro-1-(2-chlorovinyl)-1-methyl-5-methylidene-cyclohexane and two new metabolites 4,8-chloro-3,7-dimethyl-2Z,4,6Z-octatrien-1-al and Compound 3.47. Methodology was developed for the chemical derivatization and mass spectrometric analysis of the aldehydic compounds, The aldehyde trapping reagent 0-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine hydrochloride was used to derivatize the molecules, stabilizing them and allowing for their complete characterization. From Laurencia flexuosa a new cuparene sesquiterpene 4-bremo-2-(5-hydroxy-1,2,2- trimethylcyclopent-3-enyl)-5-methylphenol was isolated along with two geometric isomers of the vinyl acetylene bromofucin , An halogenated monoterpene 3S*,4R*-1-bromo-3,4,8-trichloro-9-dichloromethyl-1-E,5-E,7-Z-octatriene was also isolated but was suspected to be a contaminant and an investigation into its biological source revealed that it originated from Plocamium suhrii. A third alga, Martensia elegans was extracted based on published reports of antimicrobial compounds in related species. A new a-alkyl malate derivative was isolated and characterized. Selected compounds isolated during the course of the study were employed in preliminary assays that tested their ability to inhibit biofilm formation by Pseudomonas aeruginosa. The halogenated monoterpenes isolated from the Plocamium species were the only active compounds. 3S*,4R*-1-bromo-3,4,S-trichloro-g-dichloromethyl-1-E,5-E,7-octatriene from P. suhrii inhibited biofilm formation through antibacterial activity on planktonic cells but could not prevent biofilm formation when employed as a film on the surface of microtitre plate wells. 1,4,8-tribromo-3,7-dichloro-3,7-dimethyl-1E,5E-octadiene and 4,6-dibromo-1,1-dichloro-3,7-dimethyl-2E,7-octadiene inhibited biofilm formation when applied as a film to the microtitre plate wells but had no significant antibacterial activity. No potential antifouling agents were identified in this project but the antimicrobial activity exhibited by the crude algal extracts was highly encouraging and a number of new research areas have been identified. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
- Date Issued: 2008
Whole body vibration training effects on asthma specific pulmonary variables
- Authors: Mansell, Ingrid Joan
- Date: 2008
- Subjects: Vibration -- Physiological effect , Asthma -- Exercise therapy , Asthma -- Treatment
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:10112 , http://hdl.handle.net/10948/d1020953
- Description: The aim of the study was to determine and document evidence of the comparative effect of a 12- week whole body vibration training programme, exercise training programme and sedentary control group on the anthropometric profile, aerobic capacity, lung volumes and hence, the pulmonary capacity in people with asthma. The study used a descriptive, exploratory, quasi-experimental research approach employing randomised pairing to classify participants into either the whole body vibration therapy or exercise training group. Accidental and snowball sampling was used to identify and obtain a base of volunteers. A three-group pre-test/post-test design was employed to gain insight into statistical differences that might be apparent between the whole body vibration therapy group, the exercise group and the control group, and which could potentially be attributed to participation in the whole body vibration exercise programme. Randomised pairing for participant selection was selected because of the potential effects varying pulmonary variables might have had on the reliability of the study. A Physical Activity Selection Criteria Questionnaire was completed by participants to ascertain baseline physical activity readiness and as a means of determining selection criteria for their allocation to the whole body vibration training group, the experimental exercise group or the true control group. The pre-test/post-test assessment made use of a combination evaluation that incorporated an anthropometric profile assessment of height, weight, biceps, triceps, subscapular and suprailliac skinfolds, waist and hip circumference and posture, an aerobic capacity evaluation that incorporated aspects of both the YMCA and Astrand and Rhyming Physical Work Capacity (PWC) evaluation on a cycle ergometer and, lastly, a pulmonary variable assessment that made use of both the Datospir Peak-10 peak flow meter and the Spirovit SP-100AT spirometry unit integrated into the Cardiovit AT-6 model for all spirometry measurements. Participants were required to complete either the whole-body vibration or the exercise training programme a minimum of twice a week and a maximum of four times over the same period. The duration of the intervention programmes was approximately 30 minutes and consisted of three sections including a warm-up comprising flexibility exercises, whole body strength training exercises, and a cool-down which, in turn, consisted of massage exercises or replicated flexibility exercises. The main difference between the whole body vibration and exercise training group thus lay in the exclusion of the use of vibration for those participants assigned to the exercise training programme. Analysis of data was performed using descriptive and inferential statistics with the help of a qualified statistician. The identified variables were tested at a 95 percent level of probability (p<0.05) as recommended by Thomas and Nelson (1996:117). Descriptive data, in the form of a statistical mean, standard deviation, minimum, median and maximum values, obtained during this study were reported in the form of a t-score for selected anthropometric and pulmonary variables. The 12-week intervention programme, on analysis of the results, produced statistically insignificant improvements in the variables of anthropometric profile, aerobic capacity and lung volumes identified as determinants of, and factors influencing, the cardiorespiratory fitness level of participants with asthma and hence, the subsequent severity of this chronic condition. However, slight mean increases for the whole body vibration training group were evident for certain variables identified in this study. Based on the results, the inference could be made that whole body vibration therapy and exercise were both effective modes of training to improve the cardiorespiratory fitness level of people with asthma, but the results of the study did not show sufficient practical or statistical significance to verify the assumption that whole body vibration training was a method superior to conventional exercise training. Hence, the significance of whole body vibration training on the pulmonary variables of people with asthma could not be determined. The researcher recommends that future studies be undertaken to verify whether whole body vibration training incorporating larger participant groups could produce significant improvements in pulmonary variables in people with asthma.
- Full Text:
- Date Issued: 2008
- Authors: Mansell, Ingrid Joan
- Date: 2008
- Subjects: Vibration -- Physiological effect , Asthma -- Exercise therapy , Asthma -- Treatment
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:10112 , http://hdl.handle.net/10948/d1020953
- Description: The aim of the study was to determine and document evidence of the comparative effect of a 12- week whole body vibration training programme, exercise training programme and sedentary control group on the anthropometric profile, aerobic capacity, lung volumes and hence, the pulmonary capacity in people with asthma. The study used a descriptive, exploratory, quasi-experimental research approach employing randomised pairing to classify participants into either the whole body vibration therapy or exercise training group. Accidental and snowball sampling was used to identify and obtain a base of volunteers. A three-group pre-test/post-test design was employed to gain insight into statistical differences that might be apparent between the whole body vibration therapy group, the exercise group and the control group, and which could potentially be attributed to participation in the whole body vibration exercise programme. Randomised pairing for participant selection was selected because of the potential effects varying pulmonary variables might have had on the reliability of the study. A Physical Activity Selection Criteria Questionnaire was completed by participants to ascertain baseline physical activity readiness and as a means of determining selection criteria for their allocation to the whole body vibration training group, the experimental exercise group or the true control group. The pre-test/post-test assessment made use of a combination evaluation that incorporated an anthropometric profile assessment of height, weight, biceps, triceps, subscapular and suprailliac skinfolds, waist and hip circumference and posture, an aerobic capacity evaluation that incorporated aspects of both the YMCA and Astrand and Rhyming Physical Work Capacity (PWC) evaluation on a cycle ergometer and, lastly, a pulmonary variable assessment that made use of both the Datospir Peak-10 peak flow meter and the Spirovit SP-100AT spirometry unit integrated into the Cardiovit AT-6 model for all spirometry measurements. Participants were required to complete either the whole-body vibration or the exercise training programme a minimum of twice a week and a maximum of four times over the same period. The duration of the intervention programmes was approximately 30 minutes and consisted of three sections including a warm-up comprising flexibility exercises, whole body strength training exercises, and a cool-down which, in turn, consisted of massage exercises or replicated flexibility exercises. The main difference between the whole body vibration and exercise training group thus lay in the exclusion of the use of vibration for those participants assigned to the exercise training programme. Analysis of data was performed using descriptive and inferential statistics with the help of a qualified statistician. The identified variables were tested at a 95 percent level of probability (p<0.05) as recommended by Thomas and Nelson (1996:117). Descriptive data, in the form of a statistical mean, standard deviation, minimum, median and maximum values, obtained during this study were reported in the form of a t-score for selected anthropometric and pulmonary variables. The 12-week intervention programme, on analysis of the results, produced statistically insignificant improvements in the variables of anthropometric profile, aerobic capacity and lung volumes identified as determinants of, and factors influencing, the cardiorespiratory fitness level of participants with asthma and hence, the subsequent severity of this chronic condition. However, slight mean increases for the whole body vibration training group were evident for certain variables identified in this study. Based on the results, the inference could be made that whole body vibration therapy and exercise were both effective modes of training to improve the cardiorespiratory fitness level of people with asthma, but the results of the study did not show sufficient practical or statistical significance to verify the assumption that whole body vibration training was a method superior to conventional exercise training. Hence, the significance of whole body vibration training on the pulmonary variables of people with asthma could not be determined. The researcher recommends that future studies be undertaken to verify whether whole body vibration training incorporating larger participant groups could produce significant improvements in pulmonary variables in people with asthma.
- Full Text:
- Date Issued: 2008
A model for legal compliance in the South African banking sector : an information security perspective
- Maphakela, Madidimalo Rabbie
- Authors: Maphakela, Madidimalo Rabbie
- Date: 2008
- Subjects: Database security -- South Africa , Computer security -- South Africa , Computer networks -- Security measures -- South Africa
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:9783 , http://hdl.handle.net/10948/725 , Database security -- South Africa , Computer security -- South Africa , Computer networks -- Security measures -- South Africa
- Description: In the past, many organisations used to keep their information on paper, which resulted in the loss of important information. In today’s knowledge era the information super-highway facilitates highly connected electronic environments where business applications can communicate on an intra- as well as inter-organizational level. As business expanded more into the cyber-world, so did the need to protect the information they have. Technology advances did not only bring benefits, it also increased the vulnerability of companies’ information. Information, the lifeblood of an organization, must be protected from threats such as hackers and fraud, amongst others. In the highly regulated financial sector, the protection of information is not only a best practice, but a legal obligation carrying penalties for non-compliance. From a positive aspect, organisations can identify security controls that can help them to secure their information, with the aid of legal sources. But organisations find themselves burdened by a burgeoning number of legal sources and requirements, which require vast resources and often become unmanageable. This research focuses on finding a solution for South African banks to comply with multiple legal sources, as seen from an information security perspective.
- Full Text:
- Date Issued: 2008
- Authors: Maphakela, Madidimalo Rabbie
- Date: 2008
- Subjects: Database security -- South Africa , Computer security -- South Africa , Computer networks -- Security measures -- South Africa
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:9783 , http://hdl.handle.net/10948/725 , Database security -- South Africa , Computer security -- South Africa , Computer networks -- Security measures -- South Africa
- Description: In the past, many organisations used to keep their information on paper, which resulted in the loss of important information. In today’s knowledge era the information super-highway facilitates highly connected electronic environments where business applications can communicate on an intra- as well as inter-organizational level. As business expanded more into the cyber-world, so did the need to protect the information they have. Technology advances did not only bring benefits, it also increased the vulnerability of companies’ information. Information, the lifeblood of an organization, must be protected from threats such as hackers and fraud, amongst others. In the highly regulated financial sector, the protection of information is not only a best practice, but a legal obligation carrying penalties for non-compliance. From a positive aspect, organisations can identify security controls that can help them to secure their information, with the aid of legal sources. But organisations find themselves burdened by a burgeoning number of legal sources and requirements, which require vast resources and often become unmanageable. This research focuses on finding a solution for South African banks to comply with multiple legal sources, as seen from an information security perspective.
- Full Text:
- Date Issued: 2008
Removal and photocatalysis of 4-Nitrophenol using metallophthalocyanines
- Authors: Marais, Eloise Ann
- Date: 2008
- Subjects: Photocatalysis , Catalysis , Electrochemistry , Nitrophenols , Phthalocyanines
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4343 , http://hdl.handle.net/10962/d1005005 , Photocatalysis , Catalysis , Electrochemistry , Nitrophenols , Phthalocyanines
- Description: Photodegradation of 4-nitrophenol (4-Np) in the presence of water-soluble zinc phthalocyanines and water-insoluble metallophthalocyanines is reported. The water-soluble phthalocyanines employed include zinc tetrasulphophthalocyanine (ZnPcS[subscript 4]), zinc octacarboxyphthalocyanine (ZnPc(COOH)[subscript 8]) and a sulphonated ZnPc containing a mixture of differently sulphonated derivatives (ZnPcS[subscript mix]), while the water-insoluble phthalocyanines used include unsubstituted magnesium (MgPc), zinc (ZnPc) and chloroaluminium (ClAlPc) phthalocyanine complexes and the ring-substituted zinc tetranitro (ZnPc(NO[subscript 2])[subscript 4]), zinc tetraamino (ZnPc(NH[subscript 2])[subscript 4]), zinc hexadecafluoro (ZnPcF[subscript 16]) and zinc hexadecachloro (ZnPcCl[subscript 16]) phthalocyanines. The most effective water-soluble photocatalyst is ZnPcS[subscript mix] in terms of the high quantum yield obtained for 4-Np degradation (Φ[subscript 4-Np]) as well as its photostability. While ZnPc(COOH)[subscript 8] has the highest Φ[subscript 4-Np] value relative to the other water-soluble complexes, it degrades readily during photocatalysis. The Φ[subscript 4-Np] values were closely related to the singlet oxygen quantum yields Φ[subscript Δ] and hence aggregation. The rate constants for the reaction with 4-Np were kr = 0.67 x 10[superscript 6] mol[superscript -1] dm[superscript 3] s[superscript -1] for ZnPcS[subscript mix] and 7.7 x 10[superscript 6] mol[superscript -1] dm[superscript 3] s[superscript -1] for ZnPc(COOH)[subscript 8]. ClAlPc is the most effective photocatalyst relative to the other heterogeneous photocatalysts for the phototransformation of 4-Np, with 89 ± 8.4 % degradation of 4-Np achieved after 100 min. The least effective catalysts were ZnPcCl[subscript 16] and MgPc. The final products of the photocatalysis of 4-Np in the presence of the homogeneous photocatalysts include 4-nitrocatechol and hydroquinone, while degradation of 4-Np in the presence of the heterogeneous photocatalysts resulted in fumaric acid and 4-nitrocatechol. ClAlPc was employed for the heterogeneous photocatalysis of the non-systemic insecticide, methyl paraoxon. Complete degradation of the pesticide was confirmed by the disappearance of the HPLC trace for methyl paraoxon after 100 min of irradiation with visible light. The removal of 4-Np from an aqueous medium using commercially available Amberlite[superscript ®] IRA-900 modified with metal phthalocyanines was also investigated. The metallophthalocyanines immobilised onto the surface of Amberlite[superscript ®] IRA-900 include Fe (FePcS[subscript 4]), Co (CoPcS[subscript 4]) and Ni (NiPcS[subscript 4]) tetrasulphophthalocyanines, and differently sulphonated phthalocyanine mixtures of Fe (FePcS[subscript mix]), Co (CoPcS[subscript mix]) and Ni (NiPcS[subscript mix]). Adsorption rates were fastest for the modified adsorbents at pH 9. Using the Langmuir-Hinshelwood kinetic model, the complexes showed the following order of 4-Np adsorption: CoPcS[subscript mix] > NiPcS[subscript 4] > NiPcS[subscript mix] > FePcS[subscript 4] > FePcS[subscript mix] > CoPcS[subscript 4]. The adsorbents were regenerated using dilute HNO[subscript 3], with 76 % (7.6 x 10[superscript -5] mol) of 4-Np recovered within 150 min.
- Full Text:
- Date Issued: 2008
- Authors: Marais, Eloise Ann
- Date: 2008
- Subjects: Photocatalysis , Catalysis , Electrochemistry , Nitrophenols , Phthalocyanines
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4343 , http://hdl.handle.net/10962/d1005005 , Photocatalysis , Catalysis , Electrochemistry , Nitrophenols , Phthalocyanines
- Description: Photodegradation of 4-nitrophenol (4-Np) in the presence of water-soluble zinc phthalocyanines and water-insoluble metallophthalocyanines is reported. The water-soluble phthalocyanines employed include zinc tetrasulphophthalocyanine (ZnPcS[subscript 4]), zinc octacarboxyphthalocyanine (ZnPc(COOH)[subscript 8]) and a sulphonated ZnPc containing a mixture of differently sulphonated derivatives (ZnPcS[subscript mix]), while the water-insoluble phthalocyanines used include unsubstituted magnesium (MgPc), zinc (ZnPc) and chloroaluminium (ClAlPc) phthalocyanine complexes and the ring-substituted zinc tetranitro (ZnPc(NO[subscript 2])[subscript 4]), zinc tetraamino (ZnPc(NH[subscript 2])[subscript 4]), zinc hexadecafluoro (ZnPcF[subscript 16]) and zinc hexadecachloro (ZnPcCl[subscript 16]) phthalocyanines. The most effective water-soluble photocatalyst is ZnPcS[subscript mix] in terms of the high quantum yield obtained for 4-Np degradation (Φ[subscript 4-Np]) as well as its photostability. While ZnPc(COOH)[subscript 8] has the highest Φ[subscript 4-Np] value relative to the other water-soluble complexes, it degrades readily during photocatalysis. The Φ[subscript 4-Np] values were closely related to the singlet oxygen quantum yields Φ[subscript Δ] and hence aggregation. The rate constants for the reaction with 4-Np were kr = 0.67 x 10[superscript 6] mol[superscript -1] dm[superscript 3] s[superscript -1] for ZnPcS[subscript mix] and 7.7 x 10[superscript 6] mol[superscript -1] dm[superscript 3] s[superscript -1] for ZnPc(COOH)[subscript 8]. ClAlPc is the most effective photocatalyst relative to the other heterogeneous photocatalysts for the phototransformation of 4-Np, with 89 ± 8.4 % degradation of 4-Np achieved after 100 min. The least effective catalysts were ZnPcCl[subscript 16] and MgPc. The final products of the photocatalysis of 4-Np in the presence of the homogeneous photocatalysts include 4-nitrocatechol and hydroquinone, while degradation of 4-Np in the presence of the heterogeneous photocatalysts resulted in fumaric acid and 4-nitrocatechol. ClAlPc was employed for the heterogeneous photocatalysis of the non-systemic insecticide, methyl paraoxon. Complete degradation of the pesticide was confirmed by the disappearance of the HPLC trace for methyl paraoxon after 100 min of irradiation with visible light. The removal of 4-Np from an aqueous medium using commercially available Amberlite[superscript ®] IRA-900 modified with metal phthalocyanines was also investigated. The metallophthalocyanines immobilised onto the surface of Amberlite[superscript ®] IRA-900 include Fe (FePcS[subscript 4]), Co (CoPcS[subscript 4]) and Ni (NiPcS[subscript 4]) tetrasulphophthalocyanines, and differently sulphonated phthalocyanine mixtures of Fe (FePcS[subscript mix]), Co (CoPcS[subscript mix]) and Ni (NiPcS[subscript mix]). Adsorption rates were fastest for the modified adsorbents at pH 9. Using the Langmuir-Hinshelwood kinetic model, the complexes showed the following order of 4-Np adsorption: CoPcS[subscript mix] > NiPcS[subscript 4] > NiPcS[subscript mix] > FePcS[subscript 4] > FePcS[subscript mix] > CoPcS[subscript 4]. The adsorbents were regenerated using dilute HNO[subscript 3], with 76 % (7.6 x 10[superscript -5] mol) of 4-Np recovered within 150 min.
- Full Text:
- Date Issued: 2008
That-has-been a discussion on the body cast as that which fixes a subject in time, in relation to notions surrounding the photograph
- Authors: Maree, Christine Fae
- Date: 2008
- Subjects: Barthes, Roland. Camera Lucida Photography, Artistic Photography -- Philosophy Photographic criticism
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2412 , http://hdl.handle.net/10962/d1002208
- Description: Much like a photograph, a casts creates a replica of its referent, thereby immobilising the subject in time. While the subject continues in time and hence ages and inevitably dies the replica does not. With this basic notion of fixing a subject, I have built an argument to contextualise my sculptures, which are made using casts of elderly people. In this discussion I have looked at my works through the ideas of different theorists. The main theorist I have cited is Roland Barthes, specifically with regards to his notion of the photograph as discussed in his book Camera Lucida. I have also referenced three particular artists: Rachel Whiteread, Diane Arbus and Churchill Madikida, as I have found each of their works relate to my work in various ways, creating a different reading from each viewpoint.
- Full Text:
- Date Issued: 2008
- Authors: Maree, Christine Fae
- Date: 2008
- Subjects: Barthes, Roland. Camera Lucida Photography, Artistic Photography -- Philosophy Photographic criticism
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2412 , http://hdl.handle.net/10962/d1002208
- Description: Much like a photograph, a casts creates a replica of its referent, thereby immobilising the subject in time. While the subject continues in time and hence ages and inevitably dies the replica does not. With this basic notion of fixing a subject, I have built an argument to contextualise my sculptures, which are made using casts of elderly people. In this discussion I have looked at my works through the ideas of different theorists. The main theorist I have cited is Roland Barthes, specifically with regards to his notion of the photograph as discussed in his book Camera Lucida. I have also referenced three particular artists: Rachel Whiteread, Diane Arbus and Churchill Madikida, as I have found each of their works relate to my work in various ways, creating a different reading from each viewpoint.
- Full Text:
- Date Issued: 2008
The cryopreservation potential and ultrastructure of Agulhas sole Austroglossus pectoralis spermatozoa
- Authors: Markovina, Michael Zeljan
- Date: 2008
- Subjects: Spermatozoa , Spermatozoa -- Cryopreservation , Aquaculture , Fishes -- Breeding , Soleidae , Flatfishes , Agulhas Current (South Africa)
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5251 , http://hdl.handle.net/10962/d1005094 , Spermatozoa , Spermatozoa -- Cryopreservation , Aquaculture , Fishes -- Breeding , Soleidae , Flatfishes , Agulhas Current (South Africa)
- Description: As the estimated market demand for the Agulhas sole Austroglossus pectoralis exceeds the annual catch from trawlers, this species is a potential aquaculture candidate. Broodstock conditioning and gamete preservation is part of research and development aiming at establishing a breeding protocol for a new aquaculture species. Based on a literature review of the morphology of pleuronectiform spermatozoa, this study was designed firstly, to contribute to the field of spermatozoan morphology by describing the ultrastructure of A. pectoralis spermatozoa. This was followed by an experiment to cryopreserve mature spermatozoa to provide baseline data for future studies on this and related species. The testis of A. pectoralis was a paired structure encased in a membrane, the tunica albuginea. The primary testis was located on the dorsal surface of the rib cage and the secondary testis on the ventral side. The testis was of an unrestricted spermatogonial type, based upon observations of spermatogonia along the entire length of the lobule. Mature spermatozoa of A. pectoralis had an acrosome-free ovoid head 1.68 ± 1.6μm in length and 1.7 ± 1.6μm in diameter, a short mid-piece of 0.5 ± 0.1μm in length, containing 7 irregularly shaped mitochondria forming a ring-like structure at the base of the nucleus. The flagellae were 47.4 ± 4.8μm in length, most with two plasma membrane lateral fin-like projections. However, some flagellae had either zero or three lateral fin projections. Cross-sections of the flagellae showed an axenome with a 9+2 microtubule configuration. The proximal and distal centriols were coaxal, situated deep within the nuclear fossa. The structure of A. pectoralis spermatozoa conformed to the type 1 ect-aquasperm, also found in externally fertilizing species. This type has been suggested to be the plesiomorphic form in Neopterigians. Finally, this study contributed to a cryopreservation protocol for A. pectoralis spermatozoa by testing the two cryoprotectants dimethyl sulphoxide (DMSO) and glycerol. Glycerol, at a concentration of 10%, offered better cryoprotection than DMSO. This was established using flow cytometry analysis of post-thaw nuclear membrane integrity after 64 days of storage in liquid nitrogen. The toxicity of DMSO to isolated cellular proteins may have resulted in DMSO-treated sperm having the highest percent (35.2% ± 3.2%) of non-viable cells compared with 23.0% ± 2.5% and 27.8% ± 3.4% for glycerol and the control, respectively. The presence of sucrose in the Modified Mounib Medium extender solution may explain why 45.5% ± 5% of the sperm cells were potentially viable in the control treatment. Initially, the white margined sole Dagatichthys marginatus (Soleidae) was selected as the most suitable candidate for flatfish aquaculture in South Africa. Thus, the aim of this study was to investigate the cryogenic potential and ultrastructure of D. marginatus spermatozoa. However, due to a skewed sex ratio, there were not enough males available to study this species. A skewed sex ratio is common amongst soleids, thus, the need to develop effective cryopreservation methods and to develop an understanding of sperm morphology so that the best time for cryopreservation can be chosen. In conclusion, this first description of spermatozan morphology of A. pectoralis contributed to our understanding of soleid sperm ultrastructure. In addition, a comparison of testis appearance between fish sampled just prior to spawning season and fish with mature sperm provided information on the spawning season of this species. The findings from the cryopreservation experiment suggested that glycerol was a feasible cryoprotectant for this species when sperm was prepared under field conditions.
- Full Text:
- Date Issued: 2008
- Authors: Markovina, Michael Zeljan
- Date: 2008
- Subjects: Spermatozoa , Spermatozoa -- Cryopreservation , Aquaculture , Fishes -- Breeding , Soleidae , Flatfishes , Agulhas Current (South Africa)
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5251 , http://hdl.handle.net/10962/d1005094 , Spermatozoa , Spermatozoa -- Cryopreservation , Aquaculture , Fishes -- Breeding , Soleidae , Flatfishes , Agulhas Current (South Africa)
- Description: As the estimated market demand for the Agulhas sole Austroglossus pectoralis exceeds the annual catch from trawlers, this species is a potential aquaculture candidate. Broodstock conditioning and gamete preservation is part of research and development aiming at establishing a breeding protocol for a new aquaculture species. Based on a literature review of the morphology of pleuronectiform spermatozoa, this study was designed firstly, to contribute to the field of spermatozoan morphology by describing the ultrastructure of A. pectoralis spermatozoa. This was followed by an experiment to cryopreserve mature spermatozoa to provide baseline data for future studies on this and related species. The testis of A. pectoralis was a paired structure encased in a membrane, the tunica albuginea. The primary testis was located on the dorsal surface of the rib cage and the secondary testis on the ventral side. The testis was of an unrestricted spermatogonial type, based upon observations of spermatogonia along the entire length of the lobule. Mature spermatozoa of A. pectoralis had an acrosome-free ovoid head 1.68 ± 1.6μm in length and 1.7 ± 1.6μm in diameter, a short mid-piece of 0.5 ± 0.1μm in length, containing 7 irregularly shaped mitochondria forming a ring-like structure at the base of the nucleus. The flagellae were 47.4 ± 4.8μm in length, most with two plasma membrane lateral fin-like projections. However, some flagellae had either zero or three lateral fin projections. Cross-sections of the flagellae showed an axenome with a 9+2 microtubule configuration. The proximal and distal centriols were coaxal, situated deep within the nuclear fossa. The structure of A. pectoralis spermatozoa conformed to the type 1 ect-aquasperm, also found in externally fertilizing species. This type has been suggested to be the plesiomorphic form in Neopterigians. Finally, this study contributed to a cryopreservation protocol for A. pectoralis spermatozoa by testing the two cryoprotectants dimethyl sulphoxide (DMSO) and glycerol. Glycerol, at a concentration of 10%, offered better cryoprotection than DMSO. This was established using flow cytometry analysis of post-thaw nuclear membrane integrity after 64 days of storage in liquid nitrogen. The toxicity of DMSO to isolated cellular proteins may have resulted in DMSO-treated sperm having the highest percent (35.2% ± 3.2%) of non-viable cells compared with 23.0% ± 2.5% and 27.8% ± 3.4% for glycerol and the control, respectively. The presence of sucrose in the Modified Mounib Medium extender solution may explain why 45.5% ± 5% of the sperm cells were potentially viable in the control treatment. Initially, the white margined sole Dagatichthys marginatus (Soleidae) was selected as the most suitable candidate for flatfish aquaculture in South Africa. Thus, the aim of this study was to investigate the cryogenic potential and ultrastructure of D. marginatus spermatozoa. However, due to a skewed sex ratio, there were not enough males available to study this species. A skewed sex ratio is common amongst soleids, thus, the need to develop effective cryopreservation methods and to develop an understanding of sperm morphology so that the best time for cryopreservation can be chosen. In conclusion, this first description of spermatozan morphology of A. pectoralis contributed to our understanding of soleid sperm ultrastructure. In addition, a comparison of testis appearance between fish sampled just prior to spawning season and fish with mature sperm provided information on the spawning season of this species. The findings from the cryopreservation experiment suggested that glycerol was a feasible cryoprotectant for this species when sperm was prepared under field conditions.
- Full Text:
- Date Issued: 2008
Prevalence of ticks and tick-borne diseases in cattle on communal rangelands in the Highland Areas of the Eastern Cape Province, South Africa
- Marufu, Munyaradzi Christopher
- Authors: Marufu, Munyaradzi Christopher
- Date: 2008
- Subjects: Cattle -- Diseases , Livestock diseases -- South Africa -- Eastern Cape , Rangelands -- South Africa -- Eastern Cape , Ixodidae -- South Africa -- Eastern Cape , Tick-borne diseases -- South Africa -- Eastern Cape , Ticks -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc Agric (Animal Science)
- Identifier: vital:11814 , http://hdl.handle.net/10353/152 , Cattle -- Diseases , Livestock diseases -- South Africa -- Eastern Cape , Rangelands -- South Africa -- Eastern Cape , Ixodidae -- South Africa -- Eastern Cape , Tick-borne diseases -- South Africa -- Eastern Cape , Ticks -- South Africa -- Eastern Cape
- Description: Surveys were conducted to compare the seasonal tick prevalence and loads, and sero-prevalence of tick-borne diseases (TBD) in Nguni and non-descript cattle on the sweet and sour communal rangelands of the Eastern Cape Province. The tick species observed on both rangeland types were Rhipicephalus appendiculatus (71.0 %), Rhipicephalus (Boophilus) species (29.2 %) and Rhipicephalus evertsi evertsi (40.2 %). Hyalomma species (19.0 %) occurred only on the sour rangeland. Tick loads were higher (P < 0.05) in the hot-wet season than in the cool-dry season. Cattle in the sweet rangeland had significantly lower (P < 0.05) tick loads than those in the sour rangeland. Rhipicephalus appendiculatus loads were lower (P < 0.05) in the indigenous Nguni than non-descript cattle in the hot-wet and post-rainy season. Hyalomma species were also significantly lower (P < 0.05) in the Nguni than non-descript cattle in all the seasons. Three TBDs were observed, namely Babesia bovis (44.6 %), Babesia bigemina (45.9 %) and Anaplasma marginale (25.6 %). All the animals were sero-negative for Ehrlichia ruminantium. Nguni cattle had lower (P < 0.05) sero-prevalence for A. marginale in the cool-dry season and B. bigemina in the cool-dry and hot-wet seasons. Cattle in the sweet rangeland had significantly lower sero-prevalence of B. bovis and B. bigemina. Infection with B. bovis and A. marginale decreased (P < 0.05) the packed cell volume. Nguni cattle were recommended for use in the integrated control of ticks and TBD in the communal areas of South Africa as they were better able to cope with tick and TBD infestations than non-descript breeds.
- Full Text:
- Date Issued: 2008
- Authors: Marufu, Munyaradzi Christopher
- Date: 2008
- Subjects: Cattle -- Diseases , Livestock diseases -- South Africa -- Eastern Cape , Rangelands -- South Africa -- Eastern Cape , Ixodidae -- South Africa -- Eastern Cape , Tick-borne diseases -- South Africa -- Eastern Cape , Ticks -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc Agric (Animal Science)
- Identifier: vital:11814 , http://hdl.handle.net/10353/152 , Cattle -- Diseases , Livestock diseases -- South Africa -- Eastern Cape , Rangelands -- South Africa -- Eastern Cape , Ixodidae -- South Africa -- Eastern Cape , Tick-borne diseases -- South Africa -- Eastern Cape , Ticks -- South Africa -- Eastern Cape
- Description: Surveys were conducted to compare the seasonal tick prevalence and loads, and sero-prevalence of tick-borne diseases (TBD) in Nguni and non-descript cattle on the sweet and sour communal rangelands of the Eastern Cape Province. The tick species observed on both rangeland types were Rhipicephalus appendiculatus (71.0 %), Rhipicephalus (Boophilus) species (29.2 %) and Rhipicephalus evertsi evertsi (40.2 %). Hyalomma species (19.0 %) occurred only on the sour rangeland. Tick loads were higher (P < 0.05) in the hot-wet season than in the cool-dry season. Cattle in the sweet rangeland had significantly lower (P < 0.05) tick loads than those in the sour rangeland. Rhipicephalus appendiculatus loads were lower (P < 0.05) in the indigenous Nguni than non-descript cattle in the hot-wet and post-rainy season. Hyalomma species were also significantly lower (P < 0.05) in the Nguni than non-descript cattle in all the seasons. Three TBDs were observed, namely Babesia bovis (44.6 %), Babesia bigemina (45.9 %) and Anaplasma marginale (25.6 %). All the animals were sero-negative for Ehrlichia ruminantium. Nguni cattle had lower (P < 0.05) sero-prevalence for A. marginale in the cool-dry season and B. bigemina in the cool-dry and hot-wet seasons. Cattle in the sweet rangeland had significantly lower sero-prevalence of B. bovis and B. bigemina. Infection with B. bovis and A. marginale decreased (P < 0.05) the packed cell volume. Nguni cattle were recommended for use in the integrated control of ticks and TBD in the communal areas of South Africa as they were better able to cope with tick and TBD infestations than non-descript breeds.
- Full Text:
- Date Issued: 2008
An assessment of the child support grant as a poverty alleviation intervention in South Africa: the case of Mdantsane township in the Eastern Cape
- Authors: Mase, Blossom Bukelwa
- Date: 2008
- Subjects: Child support -- South Africa -- Eastern Cape , Child welfare -- South Africa , Child support -- Government policy -- South Africa , Poverty -- South Africa -- Eastern Cape , Children -- Services for -- South Africa
- Language: English
- Type: Thesis , Masters , M Soc Sc (Dev)
- Identifier: vital:11412 , http://hdl.handle.net/10353/299 , Child support -- South Africa -- Eastern Cape , Child welfare -- South Africa , Child support -- Government policy -- South Africa , Poverty -- South Africa -- Eastern Cape , Children -- Services for -- South Africa
- Description: There were different kinds of imbalances that were created by the past regime in which race and colour were determining factors in terms of access to state welfare. The State Maintance Grant was one of the state welfare interventions where African women did not even know how or where to access the grant. When the Child Support Grant was introduced in 1998 it gave hope to the vulnerable section of the society, the children. The CSG is one of the poverty alleviation programs introduced by the government to target the poverty stricken children of South Africa. This is a means tested program which not all children are to benefit but a certain portion of the society. There are special conditions attached to the grant which require to be fulfilled. These conditions require the child to be fed, clothed, immunized, school needs be paid, and have proper accommodation. This study made use of the Mdantsane Township which is 25 km away from East London city centre as a case study to determine whether the CSG has managed to achieve its objective of relieving poverty among children, given the conditions of poverty and unemployment in Mdantsane. The findings of this study indicate that the people of Mdantsane are still in poverty and the most affected sections remain the children. The respondents indicate that the people are unemployed as a result the CSG seems to be the source of livelihood in these households leaving the children at a disadvantage as the grant is intended for x their own needs. Therefore there is a need to investigate whether the CSG has any impact on the lives of these children. Also since Eastern Cape is known to be one of the poorest provinces, it is important to investigate whether the CSG has become the source of livelihood in some households.
- Full Text:
- Date Issued: 2008
- Authors: Mase, Blossom Bukelwa
- Date: 2008
- Subjects: Child support -- South Africa -- Eastern Cape , Child welfare -- South Africa , Child support -- Government policy -- South Africa , Poverty -- South Africa -- Eastern Cape , Children -- Services for -- South Africa
- Language: English
- Type: Thesis , Masters , M Soc Sc (Dev)
- Identifier: vital:11412 , http://hdl.handle.net/10353/299 , Child support -- South Africa -- Eastern Cape , Child welfare -- South Africa , Child support -- Government policy -- South Africa , Poverty -- South Africa -- Eastern Cape , Children -- Services for -- South Africa
- Description: There were different kinds of imbalances that were created by the past regime in which race and colour were determining factors in terms of access to state welfare. The State Maintance Grant was one of the state welfare interventions where African women did not even know how or where to access the grant. When the Child Support Grant was introduced in 1998 it gave hope to the vulnerable section of the society, the children. The CSG is one of the poverty alleviation programs introduced by the government to target the poverty stricken children of South Africa. This is a means tested program which not all children are to benefit but a certain portion of the society. There are special conditions attached to the grant which require to be fulfilled. These conditions require the child to be fed, clothed, immunized, school needs be paid, and have proper accommodation. This study made use of the Mdantsane Township which is 25 km away from East London city centre as a case study to determine whether the CSG has managed to achieve its objective of relieving poverty among children, given the conditions of poverty and unemployment in Mdantsane. The findings of this study indicate that the people of Mdantsane are still in poverty and the most affected sections remain the children. The respondents indicate that the people are unemployed as a result the CSG seems to be the source of livelihood in these households leaving the children at a disadvantage as the grant is intended for x their own needs. Therefore there is a need to investigate whether the CSG has any impact on the lives of these children. Also since Eastern Cape is known to be one of the poorest provinces, it is important to investigate whether the CSG has become the source of livelihood in some households.
- Full Text:
- Date Issued: 2008
A model for role-based security education, training and awareness in the South African healthcare environment
- Authors: Maseti, Ophola S
- Date: 2008
- Subjects: Medical care -- South Africa -- Data processing
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:9784 , http://hdl.handle.net/10948/724 , Medical care -- South Africa -- Data processing
- Description: It is generally accepted that a business operates more efficiently when it is able to consolidate information from a variety of sources. This principle applies as much in the healthcare environment. Although limited in the South African context, the use of electronic systems to access information is advancing rapidly. Many aspects have to be considered in regards to such a high availability of information, for example, training people how to access and protect information, motivating them to use the systems and information extensively and effectively, ensuring adequate levels of security, confronting ethical issues and maintaining the availability of information at crucial times. This is especially true in the healthcare sector, where access to critical data is often vital. This data must be accessed by different kinds of people with different levels of access. However, accessibility often leads to vulnerabilities. The healthcare sector deals with very sensitive data. People’s medical records need to be kept confidential; hence, security is very important. Information of a very sensitive nature is exposed to human intervention on various levels (e.g. nurses, administrative staff, general practitioners and specialists). In this scenario, it is important for each person to be aware of the requirements in terms of security and privacy, especially from a legal perspective. Because of the large dependence on the human factor in maintaining information security, organisations must employ mechanisms that address this at the staff level. One such mechanism is information security education, training and awareness programmes. As the learner is the recipient of information in such a programme, it is increasingly important that it targets the audience that it is intended for. This will maximize the benefits achieved from such a programme. This can be achieved through following a role-based approach in the design and development of the SETA programme. This research therefore proposes a model for a role-based SETA programme, with the area of application being in the South African healthcare environment.
- Full Text:
- Date Issued: 2008
- Authors: Maseti, Ophola S
- Date: 2008
- Subjects: Medical care -- South Africa -- Data processing
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:9784 , http://hdl.handle.net/10948/724 , Medical care -- South Africa -- Data processing
- Description: It is generally accepted that a business operates more efficiently when it is able to consolidate information from a variety of sources. This principle applies as much in the healthcare environment. Although limited in the South African context, the use of electronic systems to access information is advancing rapidly. Many aspects have to be considered in regards to such a high availability of information, for example, training people how to access and protect information, motivating them to use the systems and information extensively and effectively, ensuring adequate levels of security, confronting ethical issues and maintaining the availability of information at crucial times. This is especially true in the healthcare sector, where access to critical data is often vital. This data must be accessed by different kinds of people with different levels of access. However, accessibility often leads to vulnerabilities. The healthcare sector deals with very sensitive data. People’s medical records need to be kept confidential; hence, security is very important. Information of a very sensitive nature is exposed to human intervention on various levels (e.g. nurses, administrative staff, general practitioners and specialists). In this scenario, it is important for each person to be aware of the requirements in terms of security and privacy, especially from a legal perspective. Because of the large dependence on the human factor in maintaining information security, organisations must employ mechanisms that address this at the staff level. One such mechanism is information security education, training and awareness programmes. As the learner is the recipient of information in such a programme, it is increasingly important that it targets the audience that it is intended for. This will maximize the benefits achieved from such a programme. This can be achieved through following a role-based approach in the design and development of the SETA programme. This research therefore proposes a model for a role-based SETA programme, with the area of application being in the South African healthcare environment.
- Full Text:
- Date Issued: 2008
Exploring approaches to teaching reading skills in English at senior phase in secondary schools in Mbizana district in the Eastern Cape: a case study
- Masilo, Appolonia Nteboheleng
- Authors: Masilo, Appolonia Nteboheleng
- Date: 2008
- Subjects: Reading (Secondary) -- South Africa -- Eastern Cape Province
- Language: English
- Type: Thesis , Masters , M Ed
- Identifier: vital:16161 , http://hdl.handle.net/10353/204 , Reading (Secondary) -- South Africa -- Eastern Cape Province
- Description: During the process of this research, the main objective was to explore the approaches that the teachers use to teach reading in English First Additional Language (FAL) in senior phase at General Education and Training (GET). This was due to the observed weak performance of learners in reading, especially in GET phases. To achieve this, 20 participants tha t consisted of 4 English FAL teachers and 16 learners of grades 8 and 9 were selected. The research focused on teacher perceptions and implementation of language teaching approaches. Learners were involved in the research in order to see whether the used approaches give learners a balanced experience of intensive and extensive programmes. The study found that there were a number of factors that contributed to the learners’ weak performance in reading. These included, among others, lack of balance between intensive and extensive reading programmes, with intensive reading getting more attention than extensive reading; lack of reading material in schools, especially for further exposure, pleasure and amusement; little or no exposure of learners to wider reading; inadequate teacher pre-service and inservice reading programmes; teachers’ misconception of extensive reading; learners’ home environment that does not encourage reading; lack of parental support and community involvement. These all affected negatively the learners’ v development of reading skills. The study made some recommendations for the improvement of teacher education programmes and reading resources in schools and communities. schools.
- Full Text:
- Date Issued: 2008
- Authors: Masilo, Appolonia Nteboheleng
- Date: 2008
- Subjects: Reading (Secondary) -- South Africa -- Eastern Cape Province
- Language: English
- Type: Thesis , Masters , M Ed
- Identifier: vital:16161 , http://hdl.handle.net/10353/204 , Reading (Secondary) -- South Africa -- Eastern Cape Province
- Description: During the process of this research, the main objective was to explore the approaches that the teachers use to teach reading in English First Additional Language (FAL) in senior phase at General Education and Training (GET). This was due to the observed weak performance of learners in reading, especially in GET phases. To achieve this, 20 participants tha t consisted of 4 English FAL teachers and 16 learners of grades 8 and 9 were selected. The research focused on teacher perceptions and implementation of language teaching approaches. Learners were involved in the research in order to see whether the used approaches give learners a balanced experience of intensive and extensive programmes. The study found that there were a number of factors that contributed to the learners’ weak performance in reading. These included, among others, lack of balance between intensive and extensive reading programmes, with intensive reading getting more attention than extensive reading; lack of reading material in schools, especially for further exposure, pleasure and amusement; little or no exposure of learners to wider reading; inadequate teacher pre-service and inservice reading programmes; teachers’ misconception of extensive reading; learners’ home environment that does not encourage reading; lack of parental support and community involvement. These all affected negatively the learners’ v development of reading skills. The study made some recommendations for the improvement of teacher education programmes and reading resources in schools and communities. schools.
- Full Text:
- Date Issued: 2008
A critical inquiry into the absence of a gender equality discourse in the coverage of the land redistribution issue in two Zimbabwean newspapers, The Daily News and The Herald, between 01 February and 30 June 2000
- Authors: Mawarire, Jealousy Mbizvo
- Date: 2008
- Subjects: The Daily News (Zimbabwe) The Herald (Zimbabwe) Journalism -- Zimbabwe Mass media -- Social aspects -- Zimbabwe Sex in mass media -- Zimbabwe Discourse analysis -- Social aspects
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3460 , http://hdl.handle.net/10962/d1002915
- Description: The media, which help define what we think and our roles in the society, have a crucial role to project both men and women’s issues so as to change people’s perceptions and stereotypes about the role men and women play in the society. There is need, therefore, to ensure gender equality in the operations of the media so that issues to do with both men and women get adequate and equal coverage. This study on the reportage of the land redistribution exercise in Zimbabwe has, however, exposed the gendered nature of the operations of the media, particularly in the news production process. It provides that, overally, the news discourse is a masculine narrative whose androcentric form is a result of, and is protected by, claims to ‘objectivity,’ ‘professionalism’, ‘impartiality’ and the pursuit of a journalistic routine system that hegemonically prioritises men’s issues over those of women. The situation, as the research shows, has not been helped by journalists’ incapacity to do thematic appreciation of issues and their over-inclination towards a simplistic event-based journalism that fails to question policies as they are enacted and implemented in gender-skewed processes. The lack of gender policies, the operations of patriarchy and the pursuit of a journalistic routine system that sees nothing wrong with the ostracisation of women issues are very fundamental findings that the research uses in its attempts to explain why the gender equality discourse was left out of the news reports about the land reform exercise in Zimbabwe.
- Full Text:
- Date Issued: 2008
- Authors: Mawarire, Jealousy Mbizvo
- Date: 2008
- Subjects: The Daily News (Zimbabwe) The Herald (Zimbabwe) Journalism -- Zimbabwe Mass media -- Social aspects -- Zimbabwe Sex in mass media -- Zimbabwe Discourse analysis -- Social aspects
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3460 , http://hdl.handle.net/10962/d1002915
- Description: The media, which help define what we think and our roles in the society, have a crucial role to project both men and women’s issues so as to change people’s perceptions and stereotypes about the role men and women play in the society. There is need, therefore, to ensure gender equality in the operations of the media so that issues to do with both men and women get adequate and equal coverage. This study on the reportage of the land redistribution exercise in Zimbabwe has, however, exposed the gendered nature of the operations of the media, particularly in the news production process. It provides that, overally, the news discourse is a masculine narrative whose androcentric form is a result of, and is protected by, claims to ‘objectivity,’ ‘professionalism’, ‘impartiality’ and the pursuit of a journalistic routine system that hegemonically prioritises men’s issues over those of women. The situation, as the research shows, has not been helped by journalists’ incapacity to do thematic appreciation of issues and their over-inclination towards a simplistic event-based journalism that fails to question policies as they are enacted and implemented in gender-skewed processes. The lack of gender policies, the operations of patriarchy and the pursuit of a journalistic routine system that sees nothing wrong with the ostracisation of women issues are very fundamental findings that the research uses in its attempts to explain why the gender equality discourse was left out of the news reports about the land reform exercise in Zimbabwe.
- Full Text:
- Date Issued: 2008
The tax implications of a private equity buy-out : a case study of the Brait-Shoprite buy-out
- Authors: Mawire, Patrick N
- Date: 2008
- Subjects: South African Revenue Service , Consolidation and merger of corporations -- Finance , Taxation -- Law and legislation -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:8959 , http://hdl.handle.net/10948/803 , South African Revenue Service , Consolidation and merger of corporations -- Finance , Taxation -- Law and legislation -- South Africa
- Description: This treatise examines the history of private equity as a context in which to understand its role in the economy and specifically, the background for the high profile leveraged buy-outs that have been entered into in the past year. The treatise then focuses specifically on the Brait-Shoprite buy-out, examining its structure and the tax implications. The treatise then reviews the reaction of the South African Revenue Authority (“SARS”) to the buy-out and evaluates whether it was the best approach that could have been taken under the circumstances. As a result of the research, the following conclusions have been reached: Private equity transactions Private equity transactions have a role to play in the business world despite the apprehensions of tax authorities. The perception that these transactions are tax driven as part of an avoidance scheme is not justified. Structure of the Shoprite buy-out transaction: The Shoprite buy-out transaction was structured to obtain deduction for interest. The transaction was also structured to utilise the relief provisions of Part II of Chapter II (Special Provisions Relating to Companies) of the Income Tax Act no.58 of 1962, as amended (“the Act”). The relief was for capital gains tax (“CGT”) on disposal of the Shoprite assets. Finally, the transaction was designed to allow the existing shareholders to exit their investments free of Secondary Tax on Companies (“STC”). The reaction of SARS to the Shoprite buy-out transaction Whereas SARS may have been justified in questioning the structure and its impact on fiscal revenue, the response in the form of withdrawing STC relief from amalgamation transactions in section 44 was not in the best interest of a stable tax system and the majority of tax payers who are not misusing or abusing loopholes in the income tax legislation. It may have been possible for SARS to attack the structure based on the General Anti-Avoidance Rule (GAAR) in part IIA of the Chapter III of the Act.
- Full Text:
- Date Issued: 2008
- Authors: Mawire, Patrick N
- Date: 2008
- Subjects: South African Revenue Service , Consolidation and merger of corporations -- Finance , Taxation -- Law and legislation -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:8959 , http://hdl.handle.net/10948/803 , South African Revenue Service , Consolidation and merger of corporations -- Finance , Taxation -- Law and legislation -- South Africa
- Description: This treatise examines the history of private equity as a context in which to understand its role in the economy and specifically, the background for the high profile leveraged buy-outs that have been entered into in the past year. The treatise then focuses specifically on the Brait-Shoprite buy-out, examining its structure and the tax implications. The treatise then reviews the reaction of the South African Revenue Authority (“SARS”) to the buy-out and evaluates whether it was the best approach that could have been taken under the circumstances. As a result of the research, the following conclusions have been reached: Private equity transactions Private equity transactions have a role to play in the business world despite the apprehensions of tax authorities. The perception that these transactions are tax driven as part of an avoidance scheme is not justified. Structure of the Shoprite buy-out transaction: The Shoprite buy-out transaction was structured to obtain deduction for interest. The transaction was also structured to utilise the relief provisions of Part II of Chapter II (Special Provisions Relating to Companies) of the Income Tax Act no.58 of 1962, as amended (“the Act”). The relief was for capital gains tax (“CGT”) on disposal of the Shoprite assets. Finally, the transaction was designed to allow the existing shareholders to exit their investments free of Secondary Tax on Companies (“STC”). The reaction of SARS to the Shoprite buy-out transaction Whereas SARS may have been justified in questioning the structure and its impact on fiscal revenue, the response in the form of withdrawing STC relief from amalgamation transactions in section 44 was not in the best interest of a stable tax system and the majority of tax payers who are not misusing or abusing loopholes in the income tax legislation. It may have been possible for SARS to attack the structure based on the General Anti-Avoidance Rule (GAAR) in part IIA of the Chapter III of the Act.
- Full Text:
- Date Issued: 2008
The intermediary function of NGOs in HIV/AIDS responses : a case study of the Lady Frere district of the Eastern Cape
- Authors: Mayekiso, Andile
- Date: 2008 , 2013-07-11
- Subjects: HIV infections -- South Africa -- Eastern Cape AIDS (Disease) -- South Africa -- Eastern Cape Non-governmental organizations -- South Africa -- Eastern Cape Community organization -- South Africa -- Eastern Cape HIV infections -- Social aspects -- South Africa -- Eastern Cape AIDS (Disease) -- Social aspects -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3354 , http://hdl.handle.net/10962/d1007584
- Description: The HIV/AIDS epidemic has serious effects on society. It has been described as the biggest threat to the development of South Africa, with severe economic, social and human impact. In the Lady Frere District in the Eastern Cape Province, like in many other areas that are greatly affected by the epidemic in this country, young people are considered by the local Department of Health to be a particularly vulnerable group due to various predisposing biological, social, cultural, and economical factors. Despite the efforts that have been made to educate and encourage prevention, especially by the local Masibambane Non-governmental Organisation (MNGO) to inform these communities about the dangers of the epidemic, people's behaviour have been slow to change and the disease continues to spread. This research is conducted against the escalating HIV / AIDS pandemic in the Lady Frere District. The fundamental aim of this project is to examine the intermediary function of the MNGO in HIV/AIDS responses. The study seeks to evaluate the way in which this local NGO operates on the ground in contributing to a community's response to the HIV/AIDS pandemic. In other words, the thesis tries to indicate how this local NGO, in dealing with the HIV/AIDS issue, interfaces with the community and related stakeholders. It examines how young people in the Lady Frere District perceive HIV/AIDS. A literature review demonstrates that the specific aims and objectives of this project represent a fairly new area of research in South Africa. I propose in the thesis that a simple act of joining and being regularly involved in a community organisation such as the MNGO will have significant impact on individuals' health and well-being. The thesis is crying for a need to restore the notion of "ubuntu" (meaning humanity) which is fundamentally based on social capital to assist these communities to rebuild trust which is essential in people living with HIV/AIDS. Based on my assessment it seems that intermediary NGOs, like the traditional NGOs and the private sector, will have little impact in terms of changing the conditions of the poor and the marginalised people. This is because in practice, like the conventional NGOs, intermediary NGOs serve the interests of donors and national governments or those who give them financial support to continue existing.
- Full Text:
- Date Issued: 2008
- Authors: Mayekiso, Andile
- Date: 2008 , 2013-07-11
- Subjects: HIV infections -- South Africa -- Eastern Cape AIDS (Disease) -- South Africa -- Eastern Cape Non-governmental organizations -- South Africa -- Eastern Cape Community organization -- South Africa -- Eastern Cape HIV infections -- Social aspects -- South Africa -- Eastern Cape AIDS (Disease) -- Social aspects -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3354 , http://hdl.handle.net/10962/d1007584
- Description: The HIV/AIDS epidemic has serious effects on society. It has been described as the biggest threat to the development of South Africa, with severe economic, social and human impact. In the Lady Frere District in the Eastern Cape Province, like in many other areas that are greatly affected by the epidemic in this country, young people are considered by the local Department of Health to be a particularly vulnerable group due to various predisposing biological, social, cultural, and economical factors. Despite the efforts that have been made to educate and encourage prevention, especially by the local Masibambane Non-governmental Organisation (MNGO) to inform these communities about the dangers of the epidemic, people's behaviour have been slow to change and the disease continues to spread. This research is conducted against the escalating HIV / AIDS pandemic in the Lady Frere District. The fundamental aim of this project is to examine the intermediary function of the MNGO in HIV/AIDS responses. The study seeks to evaluate the way in which this local NGO operates on the ground in contributing to a community's response to the HIV/AIDS pandemic. In other words, the thesis tries to indicate how this local NGO, in dealing with the HIV/AIDS issue, interfaces with the community and related stakeholders. It examines how young people in the Lady Frere District perceive HIV/AIDS. A literature review demonstrates that the specific aims and objectives of this project represent a fairly new area of research in South Africa. I propose in the thesis that a simple act of joining and being regularly involved in a community organisation such as the MNGO will have significant impact on individuals' health and well-being. The thesis is crying for a need to restore the notion of "ubuntu" (meaning humanity) which is fundamentally based on social capital to assist these communities to rebuild trust which is essential in people living with HIV/AIDS. Based on my assessment it seems that intermediary NGOs, like the traditional NGOs and the private sector, will have little impact in terms of changing the conditions of the poor and the marginalised people. This is because in practice, like the conventional NGOs, intermediary NGOs serve the interests of donors and national governments or those who give them financial support to continue existing.
- Full Text:
- Date Issued: 2008
A study of professionalism and the professionalisation of journalists in Uganda from 1995 to 2008
- Authors: Mayiga, John Bosco
- Date: 2008
- Subjects: Journalists -- Uganda Journalism -- Political aspects -- Uganda Mass media -- Political aspects -- Uganda Journalism -- Sociological aspects -- Uganda Journalism, Commercial -- Uganda
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3461 , http://hdl.handle.net/10962/d1002916
- Description: This study seeks to examine how Ugandan journalists’ and politicians’ views on journalism professionalisation in Uganda relate to the broad theoretical arguments about professionalism within sociology and media studies. It also seeks to examine how such views impact on the democratic role of the media. The study finds out that there are two sets of distinct ideas on journalism professionalisation. The idea espoused by politicians is statutory professionalisation in which the state plays a major role through regulation and control, hence professionalisation is seen primarily as a control system. On the other hand, journalists perceive professionalisation as nurtured by voluntarily and socially inculcated professional values, hence as a value system. The study however, finds that both sets of understandings have their own complexities. While the statutory approach has complexities like how core elements of professionalism such as professional values can be imposed through legislation, the voluntary approach to professionalism also exhibits tensions within, especially stemming from the relationship between the professional and the news organisation regarding what constitutes professionalism. The study concludes that both sets of ideas have implications for the democratic role of the media, with both perceptions of professionalism curtailing this role. Statutory professionalisation in the Ugandan political context where the state is the dominant institution brings media institutions within its control, which leads to suppression of content of democratic value through a number of means. On the other hand, the self-regulatory perception does not protect media professionalism from the assault of commercial imperatives, especially when fused with state patronage in regard to broadcasting licences and placement of advertising.
- Full Text:
- Date Issued: 2008
- Authors: Mayiga, John Bosco
- Date: 2008
- Subjects: Journalists -- Uganda Journalism -- Political aspects -- Uganda Mass media -- Political aspects -- Uganda Journalism -- Sociological aspects -- Uganda Journalism, Commercial -- Uganda
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3461 , http://hdl.handle.net/10962/d1002916
- Description: This study seeks to examine how Ugandan journalists’ and politicians’ views on journalism professionalisation in Uganda relate to the broad theoretical arguments about professionalism within sociology and media studies. It also seeks to examine how such views impact on the democratic role of the media. The study finds out that there are two sets of distinct ideas on journalism professionalisation. The idea espoused by politicians is statutory professionalisation in which the state plays a major role through regulation and control, hence professionalisation is seen primarily as a control system. On the other hand, journalists perceive professionalisation as nurtured by voluntarily and socially inculcated professional values, hence as a value system. The study however, finds that both sets of understandings have their own complexities. While the statutory approach has complexities like how core elements of professionalism such as professional values can be imposed through legislation, the voluntary approach to professionalism also exhibits tensions within, especially stemming from the relationship between the professional and the news organisation regarding what constitutes professionalism. The study concludes that both sets of ideas have implications for the democratic role of the media, with both perceptions of professionalism curtailing this role. Statutory professionalisation in the Ugandan political context where the state is the dominant institution brings media institutions within its control, which leads to suppression of content of democratic value through a number of means. On the other hand, the self-regulatory perception does not protect media professionalism from the assault of commercial imperatives, especially when fused with state patronage in regard to broadcasting licences and placement of advertising.
- Full Text:
- Date Issued: 2008
Investigating the role of portfolios in developing reflective practice : a case study
- Authors: Mbango, Karolina Naango
- Date: 2008
- Subjects: Portfolios in education -- Namibia -- Case studies Student teachers -- Namibia -- Case studies Teachers -- Training of -- Namibia -- Case studies Teacher educators -- Namibia -- Case studies Reflective teaching
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1595 , http://hdl.handle.net/10962/d1003477
- Description: The purpose of this study was to investigate the purpose and role portfolios are playing in developing reflective practice in student teachers and to assess the degree to which this role is being achieved in practice. This study was a interpretive small scale case study. The target groups were 3 student teachers in their final year of study, 3 teacher educators and the vice-rector of the college. Data were obtained through interviews and document analysis. The findings indicated that the students had no meaningful orientation to both the role of portfolio development and reflective skills. The sources of this were the lack of common understanding among teacher educators, lack of support for both teacher educators and student teachers and lack of time, lack of guidelines for construction and clear assessment rubric. The results of this study indicated that the teacher educators were in need of vigorous professional development and considerable implementation strategies are needed to develop the desired reflective skills.
- Full Text:
- Date Issued: 2008
- Authors: Mbango, Karolina Naango
- Date: 2008
- Subjects: Portfolios in education -- Namibia -- Case studies Student teachers -- Namibia -- Case studies Teachers -- Training of -- Namibia -- Case studies Teacher educators -- Namibia -- Case studies Reflective teaching
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1595 , http://hdl.handle.net/10962/d1003477
- Description: The purpose of this study was to investigate the purpose and role portfolios are playing in developing reflective practice in student teachers and to assess the degree to which this role is being achieved in practice. This study was a interpretive small scale case study. The target groups were 3 student teachers in their final year of study, 3 teacher educators and the vice-rector of the college. Data were obtained through interviews and document analysis. The findings indicated that the students had no meaningful orientation to both the role of portfolio development and reflective skills. The sources of this were the lack of common understanding among teacher educators, lack of support for both teacher educators and student teachers and lack of time, lack of guidelines for construction and clear assessment rubric. The results of this study indicated that the teacher educators were in need of vigorous professional development and considerable implementation strategies are needed to develop the desired reflective skills.
- Full Text:
- Date Issued: 2008
An evaluation of the role of local economic development in promoting infrastructural development: a case study King Sabata Dalindyebo local municipality
- Authors: Mbontsi, Nandipha Siphokazi
- Date: 2008
- Subjects: Infrastructure (Economics) -- South Africa -- Eastern Cape Case studies , Local government -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , M Soc Sc (Dev)
- Identifier: vital:11416 , http://hdl.handle.net/10353/295 , Infrastructure (Economics) -- South Africa -- Eastern Cape Case studies , Local government -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape
- Description: This study examines Local Economic Development intervention strategies in relation to promoting infrastructural development with specific reference to roads as one of the vital interventions for alleviating poverty in the KSD Municipality. The study sought to evaluate the impact of the deteriorated condition of roads on the growth of economic activity and community development, the understanding of LED by both the Council and the officials, and also to evaluate LED approach on infrastructural development for poverty alleviation. The study reveals that the municipality does not understand the concept of LED as a result this has caused blockages and impediments in terms of implementing the program in the municipality. Though there are some successes achieved through the construction of the 2010 FIFA World Cup Stadium, there are key constraints related to shortages of funds, staff, skills and resources. The study has established that LED is not living up to expectations in the area, there seems to be confusion regarding its definition and application. Furthermore, there is a confusion regarding the purpose of LED whether it is purely about poverty alleviation or whether LED it is about encouraging economic growth. Ideally it should be about the combination of the two. LED clearly has a critical role to play in terms of considerations of poverty alleviation in terms of addressing development backlogs and promoting sustainable economic growth. In order to achieve this, there is a need to establish a permanent LED facilitation and support unit. The need to identify key intervention strategies, for example, the Expanded xii Public Works Program which aims at identifying labor-intensive and community construction methods. In order to achieve this the study details a number of key recommendations which are mentioned below: The need to properly define LED and its goals, also to align LED with business and market realities. There should be adequate and appropriate training of officials, adequate funding and ensuring accountability. Active encouragement of local leaders, local level forums and partnerships and close co-operation with beneficiaries should be encouraged. It is also vital to establish LED units and development agencies at local level to drive LED process. It is also important for the municipality to encourage economically viable projects which meet poverty and growth requirements and which can also encourage SMME development
- Full Text:
- Date Issued: 2008
- Authors: Mbontsi, Nandipha Siphokazi
- Date: 2008
- Subjects: Infrastructure (Economics) -- South Africa -- Eastern Cape Case studies , Local government -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , M Soc Sc (Dev)
- Identifier: vital:11416 , http://hdl.handle.net/10353/295 , Infrastructure (Economics) -- South Africa -- Eastern Cape Case studies , Local government -- South Africa -- Eastern Cape , Municipal government -- South Africa -- Eastern Cape
- Description: This study examines Local Economic Development intervention strategies in relation to promoting infrastructural development with specific reference to roads as one of the vital interventions for alleviating poverty in the KSD Municipality. The study sought to evaluate the impact of the deteriorated condition of roads on the growth of economic activity and community development, the understanding of LED by both the Council and the officials, and also to evaluate LED approach on infrastructural development for poverty alleviation. The study reveals that the municipality does not understand the concept of LED as a result this has caused blockages and impediments in terms of implementing the program in the municipality. Though there are some successes achieved through the construction of the 2010 FIFA World Cup Stadium, there are key constraints related to shortages of funds, staff, skills and resources. The study has established that LED is not living up to expectations in the area, there seems to be confusion regarding its definition and application. Furthermore, there is a confusion regarding the purpose of LED whether it is purely about poverty alleviation or whether LED it is about encouraging economic growth. Ideally it should be about the combination of the two. LED clearly has a critical role to play in terms of considerations of poverty alleviation in terms of addressing development backlogs and promoting sustainable economic growth. In order to achieve this, there is a need to establish a permanent LED facilitation and support unit. The need to identify key intervention strategies, for example, the Expanded xii Public Works Program which aims at identifying labor-intensive and community construction methods. In order to achieve this the study details a number of key recommendations which are mentioned below: The need to properly define LED and its goals, also to align LED with business and market realities. There should be adequate and appropriate training of officials, adequate funding and ensuring accountability. Active encouragement of local leaders, local level forums and partnerships and close co-operation with beneficiaries should be encouraged. It is also vital to establish LED units and development agencies at local level to drive LED process. It is also important for the municipality to encourage economically viable projects which meet poverty and growth requirements and which can also encourage SMME development
- Full Text:
- Date Issued: 2008