Synthesis and characterization of ZnO nanoparticle synthesized by a microwave-assisted combustion method and catalytic activity for the removal of ortho-nitrophenol
- Assi, Navid, Mohammadi, Ali, Sadr Manuchehri, Q, Walker, Roderick B
- Authors: Assi, Navid , Mohammadi, Ali , Sadr Manuchehri, Q , Walker, Roderick B
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183850 , vital:44075 , xlink:href="https://doi.org/10.1080/19443994.2014.891083"
- Description: ZnO nanoparticles were manufactured using microwave-assisted combustion. The structural and morphological properties of the nanoparticles were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy, and Fourier transform infrared spectroscopy. Photocatalytic degradation of ortho-nitrophenol (O-NP) in aqueous solution using the synthesized nanoparticles was performed under UV–C irradiation and is reported for the first time. The effect of the initial O-NP concentration, amount of photocatalyst, pH, and salt was investigated during photodegradation. Analysis of the degraded samples using HPLC with UV detection revealed that photocatalysis in the presence of ZnO nanoparticles removed 98% of the O-NP in 5 h. In addition, the photocatalytic degradation kinetics of O-NP were studied, and the results suggest that the data are best fitted to pseudo-first-order kinetic and Langmuir–Hinshelwood models.
- Full Text:
- Date Issued: 2015
- Authors: Assi, Navid , Mohammadi, Ali , Sadr Manuchehri, Q , Walker, Roderick B
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183850 , vital:44075 , xlink:href="https://doi.org/10.1080/19443994.2014.891083"
- Description: ZnO nanoparticles were manufactured using microwave-assisted combustion. The structural and morphological properties of the nanoparticles were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy, and Fourier transform infrared spectroscopy. Photocatalytic degradation of ortho-nitrophenol (O-NP) in aqueous solution using the synthesized nanoparticles was performed under UV–C irradiation and is reported for the first time. The effect of the initial O-NP concentration, amount of photocatalyst, pH, and salt was investigated during photodegradation. Analysis of the degraded samples using HPLC with UV detection revealed that photocatalysis in the presence of ZnO nanoparticles removed 98% of the O-NP in 5 h. In addition, the photocatalytic degradation kinetics of O-NP were studied, and the results suggest that the data are best fitted to pseudo-first-order kinetic and Langmuir–Hinshelwood models.
- Full Text:
- Date Issued: 2015
Participatory communications as a tool for women’s empowerment: A study of five community radio stations in Northern Ghana
- Authors: Asuman, Kofi Antwi Manfred
- Date: 2022-12
- Subjects: Women in agriculture -- Africa -- Ghana , Agricultural development , Community radios – Ghana
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/59293 , vital:62026
- Description: In the process of achieving social equity and local development in Ghana, the empowerment and improvement of the lives of women remain critical factors, because of the existing role women and girls assume in the household and larger communal setting. In Northern Ghana culture and religion have historically side-lined, and in some cases, completely excluded women from participating in the dialogues, economic and political processes that lead to, or facilitate the transformation and development of their households and communities. Even though the media has largely contributed to the discrimination and stereotype of women through how women are represented in mainstream media, the Ghanaian media, in its assumed role as the “fourth estate of the realm” has the power to explicitly advocate and implicitly frame messages which can accelerate the processes of social change, women’s empowerment and social inclusion through the community radio broadcast system (Diedong, 2017: pp. 59, 64). After 30 years of the liberalization of the Ghanaian media and 25 years after the opening of the first community radio station, there have been few studies of how community radio influences women’s empowerment, how it gives opportunity for women to participate in political processes and whether, and how, it strengthens the livelihood capabilities of women. This research was motivated by the empowerment theory and the theory of participatory development communications. The researcher also makes references to feminist media theory in his arguments about the need for women to have access to radio in order to make their own content and also listen to content produced by other women. This study adopted a mixed methods research approach and collected data through programme analysis of the sampled radio stations, focus group discussions and semi-structured interviews. After field data was collected, they were analysed in themes that focus on the objectives of this study, data is presented through thematic discourse methods in order to help the researcher draw conclusions and propose a framework to guide practitioners in the implementation of communication for development projects which use mass media in targeting women for development objectives. My analyses are broadly presented in three chapters with each chapter focusing on one research objective. Based on the data, the researcher discovered that, community radio improves the livelihoods of women in Northern Ghana by providing them with agricultural programming which teaches women new farming techniques and how to practice sustainable agriculture while improving the yield of their crops. The study also found out that community radio provides. opportunities for women to monitor how public funds meant for community development projects are allocated, disbursed, and used for their intended purposes, by creating an avenue of two-way communication and dialogue between women, their district officers, and their elected leaders. Based on the findings of the study, the researcher concludes that, it is important for development practitioners who use mass media to implement women-focused projects to conduct a contextual analysis of the communities, the women, and the identified stakeholders of the intended project because every community is unique. Whereas all women in rural areas are vulnerable and underprivileged. To some extent, their needs and preferences are different because of their different levels of education and income status. , Thesis (PhD) -- Faculty of Humanities, School of Language and Communications, 2022
- Full Text:
- Date Issued: 2022-12
- Authors: Asuman, Kofi Antwi Manfred
- Date: 2022-12
- Subjects: Women in agriculture -- Africa -- Ghana , Agricultural development , Community radios – Ghana
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/59293 , vital:62026
- Description: In the process of achieving social equity and local development in Ghana, the empowerment and improvement of the lives of women remain critical factors, because of the existing role women and girls assume in the household and larger communal setting. In Northern Ghana culture and religion have historically side-lined, and in some cases, completely excluded women from participating in the dialogues, economic and political processes that lead to, or facilitate the transformation and development of their households and communities. Even though the media has largely contributed to the discrimination and stereotype of women through how women are represented in mainstream media, the Ghanaian media, in its assumed role as the “fourth estate of the realm” has the power to explicitly advocate and implicitly frame messages which can accelerate the processes of social change, women’s empowerment and social inclusion through the community radio broadcast system (Diedong, 2017: pp. 59, 64). After 30 years of the liberalization of the Ghanaian media and 25 years after the opening of the first community radio station, there have been few studies of how community radio influences women’s empowerment, how it gives opportunity for women to participate in political processes and whether, and how, it strengthens the livelihood capabilities of women. This research was motivated by the empowerment theory and the theory of participatory development communications. The researcher also makes references to feminist media theory in his arguments about the need for women to have access to radio in order to make their own content and also listen to content produced by other women. This study adopted a mixed methods research approach and collected data through programme analysis of the sampled radio stations, focus group discussions and semi-structured interviews. After field data was collected, they were analysed in themes that focus on the objectives of this study, data is presented through thematic discourse methods in order to help the researcher draw conclusions and propose a framework to guide practitioners in the implementation of communication for development projects which use mass media in targeting women for development objectives. My analyses are broadly presented in three chapters with each chapter focusing on one research objective. Based on the data, the researcher discovered that, community radio improves the livelihoods of women in Northern Ghana by providing them with agricultural programming which teaches women new farming techniques and how to practice sustainable agriculture while improving the yield of their crops. The study also found out that community radio provides. opportunities for women to monitor how public funds meant for community development projects are allocated, disbursed, and used for their intended purposes, by creating an avenue of two-way communication and dialogue between women, their district officers, and their elected leaders. Based on the findings of the study, the researcher concludes that, it is important for development practitioners who use mass media to implement women-focused projects to conduct a contextual analysis of the communities, the women, and the identified stakeholders of the intended project because every community is unique. Whereas all women in rural areas are vulnerable and underprivileged. To some extent, their needs and preferences are different because of their different levels of education and income status. , Thesis (PhD) -- Faculty of Humanities, School of Language and Communications, 2022
- Full Text:
- Date Issued: 2022-12
An integrated framework for assessing coastal community vulnerability across cultures, oceans and scales
- Aswani, Shankar, Howard, J A, Gasalla, Maria A, Jennings, Sarah, Malherbe, W, Martins, I M, Salim Shyam, Van Putten, Ingrid E, Swathilekshmi, P S, Narayanakumar, R, Watmough G R
- Authors: Aswani, Shankar , Howard, J A , Gasalla, Maria A , Jennings, Sarah , Malherbe, W , Martins, I M , Salim Shyam , Van Putten, Ingrid E , Swathilekshmi, P S , Narayanakumar, R , Watmough G R
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/421581 , vital:71863 , xlink:href="https://doi.org/10.1080/17565529.2018.1442795"
- Description: Coastal communities are some of the most at-risk populations with respect to climate change impacts. It is therefore important to determine the vulnerability of such communities to co-develop viable adaptation options. Global efforts to address this issue include international scientific projects, such as Global Learning for Local Solutions (GULLS), which focuses on five fast warming regions of the southern hemisphere and aims to provide an understanding of the local scale processes influencing community vulnerability that can then be up-scaled to regional, country and global levels. This paper describes the development of a new social and ecological vulnerability framework which integrates exposure, sensitivity and adaptive capacity with the social livelihoods and food security approaches. It also measures community flexibility to understand better the adaptive capacity of different levels of community organization. The translation of the conceptual framework to an implementable method is described and its application in a number of “hotspot” countries, where ocean waters are warming faster than the rest of the world, is presented. Opportunities for cross-cultural comparisons to uncover similarities and differences in vulnerability and adaptation patterns among the study’s coastal communities, which can provide accelerated learning mechanisms to other coastal regions, are highlighted. The social and ecological framework and the associated survey approach allow for future integration of local-level vulnerability data with ecological and oceanographic models.
- Full Text:
- Date Issued: 2019
- Authors: Aswani, Shankar , Howard, J A , Gasalla, Maria A , Jennings, Sarah , Malherbe, W , Martins, I M , Salim Shyam , Van Putten, Ingrid E , Swathilekshmi, P S , Narayanakumar, R , Watmough G R
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/421581 , vital:71863 , xlink:href="https://doi.org/10.1080/17565529.2018.1442795"
- Description: Coastal communities are some of the most at-risk populations with respect to climate change impacts. It is therefore important to determine the vulnerability of such communities to co-develop viable adaptation options. Global efforts to address this issue include international scientific projects, such as Global Learning for Local Solutions (GULLS), which focuses on five fast warming regions of the southern hemisphere and aims to provide an understanding of the local scale processes influencing community vulnerability that can then be up-scaled to regional, country and global levels. This paper describes the development of a new social and ecological vulnerability framework which integrates exposure, sensitivity and adaptive capacity with the social livelihoods and food security approaches. It also measures community flexibility to understand better the adaptive capacity of different levels of community organization. The translation of the conceptual framework to an implementable method is described and its application in a number of “hotspot” countries, where ocean waters are warming faster than the rest of the world, is presented. Opportunities for cross-cultural comparisons to uncover similarities and differences in vulnerability and adaptation patterns among the study’s coastal communities, which can provide accelerated learning mechanisms to other coastal regions, are highlighted. The social and ecological framework and the associated survey approach allow for future integration of local-level vulnerability data with ecological and oceanographic models.
- Full Text:
- Date Issued: 2019
Detecting change in local ecological knowledge: An application of an index of taxonomic distinctness to an ethnoichthyological classification in the Solomon Islands
- Aswani, Shankar, Ferse, Sebastien C, Stäbler, Moritz, Chong-Montenegro, Carolina
- Authors: Aswani, Shankar , Ferse, Sebastien C , Stäbler, Moritz , Chong-Montenegro, Carolina
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/406521 , vital:70282 , xlink:href="https://doi.org/10.1016/j.ecolind.2020.106865"
- Description: The global accelerating loss of biodiversity is having immediate repercussions for ecosystems and human wellbeing, particularly in areas where people depend intimately on their natural environment for their livelihoods. Dovetailing this loss is the demise of local/traditional knowledge systems resulting from factors such as changing lifestyle and the transformation of local belief systems. While the importance of local ecological knowledge (LEK) for documentation of biodiversity and environmental change and development of management responses is well established, quantitative tools to analyze and systematically compare LEK are scarce. In this research, we analyze the complexity of local ecological knowledge used by respondents to classify locally-recognized marine species. We do so by applying a modified index of taxonomic distinctness to an ethnoichthyological classification in coastal communities in the Solomon Islands. In addition, we assess simple taxonomic diversity (richness in locally-recognized species names) by comparing taxonomies collected in 1992–1995 and 2014–2015. Results indicate that both endogenous (gender, age) and exogenous (proximity to market) factors have discernible effects on folk taxonomic knowledge in the region, with younger respondents and communities closer to a regional market center displaying a significantly lower richness of local species names. Folk taxonomic distinctness was significantly reduced closer to the regional market. The modified index of taxonomic distinctness applied in this research provides a useful tool to explore facets of local ecological knowledge in addition to simple richness of terms, and to compare across different regions and cultural backgrounds. Understanding changes in LEK is important because such knowledge enables communities who are highly dependent on living natural resources to harvest and manage resources more efficiently and also to detect and react to environmental change.
- Full Text:
- Date Issued: 2020
- Authors: Aswani, Shankar , Ferse, Sebastien C , Stäbler, Moritz , Chong-Montenegro, Carolina
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/406521 , vital:70282 , xlink:href="https://doi.org/10.1016/j.ecolind.2020.106865"
- Description: The global accelerating loss of biodiversity is having immediate repercussions for ecosystems and human wellbeing, particularly in areas where people depend intimately on their natural environment for their livelihoods. Dovetailing this loss is the demise of local/traditional knowledge systems resulting from factors such as changing lifestyle and the transformation of local belief systems. While the importance of local ecological knowledge (LEK) for documentation of biodiversity and environmental change and development of management responses is well established, quantitative tools to analyze and systematically compare LEK are scarce. In this research, we analyze the complexity of local ecological knowledge used by respondents to classify locally-recognized marine species. We do so by applying a modified index of taxonomic distinctness to an ethnoichthyological classification in coastal communities in the Solomon Islands. In addition, we assess simple taxonomic diversity (richness in locally-recognized species names) by comparing taxonomies collected in 1992–1995 and 2014–2015. Results indicate that both endogenous (gender, age) and exogenous (proximity to market) factors have discernible effects on folk taxonomic knowledge in the region, with younger respondents and communities closer to a regional market center displaying a significantly lower richness of local species names. Folk taxonomic distinctness was significantly reduced closer to the regional market. The modified index of taxonomic distinctness applied in this research provides a useful tool to explore facets of local ecological knowledge in addition to simple richness of terms, and to compare across different regions and cultural backgrounds. Understanding changes in LEK is important because such knowledge enables communities who are highly dependent on living natural resources to harvest and manage resources more efficiently and also to detect and react to environmental change.
- Full Text:
- Date Issued: 2020
Design of Realistic Hybrid Marine Resource Management Programs in Oceania
- Aswani, Shankar, Ruddle, Kenneth
- Authors: Aswani, Shankar , Ruddle, Kenneth
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/422721 , vital:71972 , xlink:href="https://doi.org/10.2984/67.3.11"
- Description: This review article synthesizes the authors' several decades of multidisciplinary natural and social science and applied marine resource management experience in the Asia-Pacific region to examine the strengthening of coastal and marine resource management and conservation using alliances between local communities and external institutions. The objective is to assist the design of resource management and conservation programs that enhance the capacity of coastal communities in Oceania to confront both diminishing marine resources and the effects of climate change by providing guidelines for protecting marine biodiversity and vulnerable ecosystem functions. This article describes a management framework that hybridizes local beliefs and institutions expressed in customary management (CM) with such modern management concepts as marine protected areas (MPAs) and ecosystem-based management (EBM). Hybrid management accommodates the social, political, economic, and cultural contexts of Oceanic communities and, compared with recent or conventional management approaches, can therefore better address fundamental local concerns such as coastal degradation, climate change, sea level rise, weak governance, corruption, limited resources and staff to manage and monitor marine resources, and increasing poverty. Research on the hybridization of management systems demonstrates opportunities to establish context-appropriate EBM and/or other managerial arrangements that include terrestrial and adjacent coastal-marine ecosystems. Formal and informal CM systems are widespread in Oceania and in some parts of Southeast Asia, and if appropriate strategies are employed rapid progress toward hybrid CM-EBM could be enabled.
- Full Text:
- Date Issued: 2013
- Authors: Aswani, Shankar , Ruddle, Kenneth
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/422721 , vital:71972 , xlink:href="https://doi.org/10.2984/67.3.11"
- Description: This review article synthesizes the authors' several decades of multidisciplinary natural and social science and applied marine resource management experience in the Asia-Pacific region to examine the strengthening of coastal and marine resource management and conservation using alliances between local communities and external institutions. The objective is to assist the design of resource management and conservation programs that enhance the capacity of coastal communities in Oceania to confront both diminishing marine resources and the effects of climate change by providing guidelines for protecting marine biodiversity and vulnerable ecosystem functions. This article describes a management framework that hybridizes local beliefs and institutions expressed in customary management (CM) with such modern management concepts as marine protected areas (MPAs) and ecosystem-based management (EBM). Hybrid management accommodates the social, political, economic, and cultural contexts of Oceanic communities and, compared with recent or conventional management approaches, can therefore better address fundamental local concerns such as coastal degradation, climate change, sea level rise, weak governance, corruption, limited resources and staff to manage and monitor marine resources, and increasing poverty. Research on the hybridization of management systems demonstrates opportunities to establish context-appropriate EBM and/or other managerial arrangements that include terrestrial and adjacent coastal-marine ecosystems. Formal and informal CM systems are widespread in Oceania and in some parts of Southeast Asia, and if appropriate strategies are employed rapid progress toward hybrid CM-EBM could be enabled.
- Full Text:
- Date Issued: 2013
An investigation of traveling ionospheric disturbances (TIDs) in the SANAE HF radar data
- Authors: Atilaw, Tsige Yared
- Date: 2022-04-07
- Subjects: Ionospheric storms Antarctica , Radar Antarctica , Range time-intensity (RTI) , South African National Antarctic Expedition (SANAE) , Super Dual Auroral Radar Network (SuperDARN)
- Language: English
- Type: Doctoral thesis , text
- Identifier: http://hdl.handle.net/10962/232377 , vital:49986 , DOI 10.21504/10962/232377
- Description: This thesis aims to study the characteristics of traveling ionospheric disturbances (TIDs) as identified in the radar data of the South African National Antarctic Expedition (SANAE) Super Dual Auroral Radar Network (SuperDARN) radar located in Antarctica. For this project, 22 TIDs were identified from visual inspection of range time-intensity (RTI) plots of backscattered power and Doppler velocity parameters of the SANAE radar between 2005âAS2015. These events were studied to determine their characteristics and driving mechanisms. Where good quality data were available, the SANAE HF radar data were supplemented by Halley radar data, which has large area of overlapping field of view (FOV) with the SANAE radar, and also by GPS TEC data. This provided a multi-instrument data analysis of some TID events. Different spectral analysis methods, namely the multitaper method (MTM), Fast Fourier transform (FFT) and the Lomb-Scargle periodogram were used to obtain spectral information of the observed waves. The advantage of using multiple windowing in MTM over the traditional windowing method was illustrated using one of the TID events. In addition, the analytic signal of the wave from the MTM method was used to estimate the instantaneous phase velocity and propagation azimuth of the wave, which was able to track the change in the characteristics of the medium-scale TID (MSTID) efficiently throughout the duration of the event. This is a clear advantage over other windowing techniques. The energy contribution by this MSTID through Joule heating was estimated over the region where spectral analysis of both SANAE and Halley data showed it to be present. The majority of the TIDs (65.4%) could be classified as MSTIDs with periods of 20–60 minutes, velocities of 50–333 ms1 and wavelengths of 129–833 km. The TID occurrence rate was high around the March equinox with 12 out of the 16 event days being during March–May. March had a particularly high number of occurrences of TIDs (46%). The majority of the TIDs observed during this month propagated northward or southeastward. In terms of prevailing geomagnetic conditions, 6 out of 16 event days were geomagnetically quiet, while 10 occurred during geomagnetic storms and substorms. During quiet conditions, TIDs could be linked to Es and polarised electric fields in 2 of these events. The other quiet time events could not be related to Es instability and polarised electric field either because their exact propagation direction could not be determined or data quality from the Es region scatter was too poor to perform spectral analysis. The storm-/substorm-related TIDs are possibly generated through Joule heating, the Lorentz force and energetic particle precipitation. , Thesis (PhD) -- Faculty of Science, Physics and Electronics, 2022
- Full Text:
- Date Issued: 2022-04-07
- Authors: Atilaw, Tsige Yared
- Date: 2022-04-07
- Subjects: Ionospheric storms Antarctica , Radar Antarctica , Range time-intensity (RTI) , South African National Antarctic Expedition (SANAE) , Super Dual Auroral Radar Network (SuperDARN)
- Language: English
- Type: Doctoral thesis , text
- Identifier: http://hdl.handle.net/10962/232377 , vital:49986 , DOI 10.21504/10962/232377
- Description: This thesis aims to study the characteristics of traveling ionospheric disturbances (TIDs) as identified in the radar data of the South African National Antarctic Expedition (SANAE) Super Dual Auroral Radar Network (SuperDARN) radar located in Antarctica. For this project, 22 TIDs were identified from visual inspection of range time-intensity (RTI) plots of backscattered power and Doppler velocity parameters of the SANAE radar between 2005âAS2015. These events were studied to determine their characteristics and driving mechanisms. Where good quality data were available, the SANAE HF radar data were supplemented by Halley radar data, which has large area of overlapping field of view (FOV) with the SANAE radar, and also by GPS TEC data. This provided a multi-instrument data analysis of some TID events. Different spectral analysis methods, namely the multitaper method (MTM), Fast Fourier transform (FFT) and the Lomb-Scargle periodogram were used to obtain spectral information of the observed waves. The advantage of using multiple windowing in MTM over the traditional windowing method was illustrated using one of the TID events. In addition, the analytic signal of the wave from the MTM method was used to estimate the instantaneous phase velocity and propagation azimuth of the wave, which was able to track the change in the characteristics of the medium-scale TID (MSTID) efficiently throughout the duration of the event. This is a clear advantage over other windowing techniques. The energy contribution by this MSTID through Joule heating was estimated over the region where spectral analysis of both SANAE and Halley data showed it to be present. The majority of the TIDs (65.4%) could be classified as MSTIDs with periods of 20–60 minutes, velocities of 50–333 ms1 and wavelengths of 129–833 km. The TID occurrence rate was high around the March equinox with 12 out of the 16 event days being during March–May. March had a particularly high number of occurrences of TIDs (46%). The majority of the TIDs observed during this month propagated northward or southeastward. In terms of prevailing geomagnetic conditions, 6 out of 16 event days were geomagnetically quiet, while 10 occurred during geomagnetic storms and substorms. During quiet conditions, TIDs could be linked to Es and polarised electric fields in 2 of these events. The other quiet time events could not be related to Es instability and polarised electric field either because their exact propagation direction could not be determined or data quality from the Es region scatter was too poor to perform spectral analysis. The storm-/substorm-related TIDs are possibly generated through Joule heating, the Lorentz force and energetic particle precipitation. , Thesis (PhD) -- Faculty of Science, Physics and Electronics, 2022
- Full Text:
- Date Issued: 2022-04-07
Synthesis, Photophysical and Photochemical Properties of Poly (oxyethylene)‐Substituted Phthalocyaninato Oxotitanium (IV) Complexes
- Atilla, Devrim, Durmus, Mahmut, Yılmaz, Özgür, Gürek, Ayşe Gül, Ahsen, Vefa, Nyokong, Tebello
- Authors: Atilla, Devrim , Durmus, Mahmut , Yılmaz, Özgür , Gürek, Ayşe Gül , Ahsen, Vefa , Nyokong, Tebello
- Date: 2007
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/271263 , vital:54526 , xlink:href="https://doi.org/10.1002/ejic.200700057"
- Description: The synthesis, photophysical and photochemical properties of tetra- and chlorotetrapoly(oxyethylene)-substituted oxotitanium(IV) phthalocyanines are reported for the first time. The new compounds were characterized by elemental analysis, IR, 1H and 13C NMR spectroscopy, electronic spectroscopy and mass spectra. These complexes showed monomeric behaviour in solution. General trends are described for photodegredation, singlet oxygen, triplet state and fluorescence quantum yields, and triplet and fluorescence lifetimes of these compounds in dimethyl sulfoxide (DMSO). Photophysical and photochemical properties of phthalocyanine complexes are very useful for PDT applications. The complexes showed high triplet quantum yields and triplet lifetimes in DMSO. The singlet oxygen quantum yields (ΦΔ), which give an indication of the potential of the complexes as photosensitizers in applications where singlet oxygen is required (Type II mechanism), were 0.72 and 0.78 for 3a and 5a, respectively. Thus, these complexes show potential as Type II photosensitizers. These complexes were also quenched by benzoquinone for fluorescence quenching studies.
- Full Text:
- Date Issued: 2007
- Authors: Atilla, Devrim , Durmus, Mahmut , Yılmaz, Özgür , Gürek, Ayşe Gül , Ahsen, Vefa , Nyokong, Tebello
- Date: 2007
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/271263 , vital:54526 , xlink:href="https://doi.org/10.1002/ejic.200700057"
- Description: The synthesis, photophysical and photochemical properties of tetra- and chlorotetrapoly(oxyethylene)-substituted oxotitanium(IV) phthalocyanines are reported for the first time. The new compounds were characterized by elemental analysis, IR, 1H and 13C NMR spectroscopy, electronic spectroscopy and mass spectra. These complexes showed monomeric behaviour in solution. General trends are described for photodegredation, singlet oxygen, triplet state and fluorescence quantum yields, and triplet and fluorescence lifetimes of these compounds in dimethyl sulfoxide (DMSO). Photophysical and photochemical properties of phthalocyanine complexes are very useful for PDT applications. The complexes showed high triplet quantum yields and triplet lifetimes in DMSO. The singlet oxygen quantum yields (ΦΔ), which give an indication of the potential of the complexes as photosensitizers in applications where singlet oxygen is required (Type II mechanism), were 0.72 and 0.78 for 3a and 5a, respectively. Thus, these complexes show potential as Type II photosensitizers. These complexes were also quenched by benzoquinone for fluorescence quenching studies.
- Full Text:
- Date Issued: 2007
Synthesis and photodynamic potential of tetra-and octa-triethyleneoxysulfonyl substituted zinc phthalocyanines
- Atilla, Devrim, Savdan, Nil, Durmus, Mahmut, Gürek, Ayşe Gül, Khan, Tania, Rück, Angelika, Walt, Heinrich, Nyokong, Tebello, Ahsen, Vefa
- Authors: Atilla, Devrim , Savdan, Nil , Durmus, Mahmut , Gürek, Ayşe Gül , Khan, Tania , Rück, Angelika , Walt, Heinrich , Nyokong, Tebello , Ahsen, Vefa
- Date: 2007
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/281342 , vital:55715 , xlink:href="https://doi.org/10.1016/j.jphotochem.2006.08.022"
- Description: Synthesis of the water soluble zinc phthalocyanines (3, 4) obtained from the phthalonitriles substituted with oligo(ethyleneoxy)thia groups are described. The new compounds have been characterized by elemental analysis, IR, 1H and 13C NMR spectroscopy, including HSQC, HMBC and COSY bidimensional correlation techniques, electronic spectroscopy and mass spectra. The aggregation behaviour of the phthalocyanine compounds (3, 4) was investigated using UV–vis spectroscopy in dimethylsulphoxide. Photochemical and photophysical measurements were conducted on oligo(ethyleneoxy)thia appended zinc phthalocyanines. General trends are described for quantum yields of photodegredation, fluorescence yields, triplet lifetimes and triplet quantum yields as well as singlet oxygen quantum yields of these compounds. The phototoxicity against cancer cells of the new compounds was investigated during several in vitro experiments. The dye-sensitized photooxidation of 1,3-diphenylisobenzofurane via 1O2 was studied in dimethylsulphoxide.
- Full Text:
- Date Issued: 2007
- Authors: Atilla, Devrim , Savdan, Nil , Durmus, Mahmut , Gürek, Ayşe Gül , Khan, Tania , Rück, Angelika , Walt, Heinrich , Nyokong, Tebello , Ahsen, Vefa
- Date: 2007
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/281342 , vital:55715 , xlink:href="https://doi.org/10.1016/j.jphotochem.2006.08.022"
- Description: Synthesis of the water soluble zinc phthalocyanines (3, 4) obtained from the phthalonitriles substituted with oligo(ethyleneoxy)thia groups are described. The new compounds have been characterized by elemental analysis, IR, 1H and 13C NMR spectroscopy, including HSQC, HMBC and COSY bidimensional correlation techniques, electronic spectroscopy and mass spectra. The aggregation behaviour of the phthalocyanine compounds (3, 4) was investigated using UV–vis spectroscopy in dimethylsulphoxide. Photochemical and photophysical measurements were conducted on oligo(ethyleneoxy)thia appended zinc phthalocyanines. General trends are described for quantum yields of photodegredation, fluorescence yields, triplet lifetimes and triplet quantum yields as well as singlet oxygen quantum yields of these compounds. The phototoxicity against cancer cells of the new compounds was investigated during several in vitro experiments. The dye-sensitized photooxidation of 1,3-diphenylisobenzofurane via 1O2 was studied in dimethylsulphoxide.
- Full Text:
- Date Issued: 2007
South African traditional healers’ perceptions and treatment of the symptoms of depression
- Authors: Augustine, Daniella Joan
- Date: 2023-03-30
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408789 , vital:70525
- Description: While depression is experienced worldwide, the World Health Organization indicated that over 80% of this disease burden is found in low- and middle-income countries, with 16% of depressive disorder cases being found in Africa. Specifically, in South Africa, the lifetime prevalence of major depressive disorder is 9.7%. Research conducted on traditional healing estimates that as high as 80% of black individuals in South Africa choose to consult traditional healers. Although there was initial consensus that the use of traditional healers reflected a lack of access to alternative resources, more recent research has however indicated that traditional healers are consulted even when psychiatric facilities and medication are available. Research has illustrated that many patients that chose to consult traditional healers do so as a result of their shared beliefs, and traditional healers' ability to understand the cultural frameworks underlying illness. The current study investigated how traditional healers in the Eastern Cape perceive and treat phenomena currently understood as the symptoms of depression and how these understandings can be incorporated into collaborations between Western medicine and traditional healing practice. A qualitative research design was used to examine the perspectives and treatment methods of isiXhosa traditional healers in the Eastern Cape. Four healers participated in the study. Key findings indicated that there is no single cause or definition of the phenomenon of depression by healers. Causality is greatly attributed to spiritual causes and ancestors play a key role in guiding the diagnosis and multiple treatment interventions employed by healers to treat the experience of depression. Finally, all traditional healers expressed a willingness to collaborate and work with the Western healthcare system, however, they indicated a strong need for greater recognition as a valid healthcare system. , Thesis (MA) -- Faculty of Humanities, Psychology, 2023
- Full Text:
- Date Issued: 2023-03-30
- Authors: Augustine, Daniella Joan
- Date: 2023-03-30
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408789 , vital:70525
- Description: While depression is experienced worldwide, the World Health Organization indicated that over 80% of this disease burden is found in low- and middle-income countries, with 16% of depressive disorder cases being found in Africa. Specifically, in South Africa, the lifetime prevalence of major depressive disorder is 9.7%. Research conducted on traditional healing estimates that as high as 80% of black individuals in South Africa choose to consult traditional healers. Although there was initial consensus that the use of traditional healers reflected a lack of access to alternative resources, more recent research has however indicated that traditional healers are consulted even when psychiatric facilities and medication are available. Research has illustrated that many patients that chose to consult traditional healers do so as a result of their shared beliefs, and traditional healers' ability to understand the cultural frameworks underlying illness. The current study investigated how traditional healers in the Eastern Cape perceive and treat phenomena currently understood as the symptoms of depression and how these understandings can be incorporated into collaborations between Western medicine and traditional healing practice. A qualitative research design was used to examine the perspectives and treatment methods of isiXhosa traditional healers in the Eastern Cape. Four healers participated in the study. Key findings indicated that there is no single cause or definition of the phenomenon of depression by healers. Causality is greatly attributed to spiritual causes and ancestors play a key role in guiding the diagnosis and multiple treatment interventions employed by healers to treat the experience of depression. Finally, all traditional healers expressed a willingness to collaborate and work with the Western healthcare system, however, they indicated a strong need for greater recognition as a valid healthcare system. , Thesis (MA) -- Faculty of Humanities, Psychology, 2023
- Full Text:
- Date Issued: 2023-03-30
The role of visualisation in redefining the pedagogy of fractions in mathematics classrooms among senior primary school teachers
- Authors: Ausiku, Charity Makwiliro
- Date: 2022-10-14
- Subjects: Mathematics Study and teaching (Elementary) Namibia , Fractions Study and teaching (Elementary) Namibia , Visualization , Visual learning , Dual-coding hypothesis , Constructivism (Education) Namibia
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/405456 , vital:70173 , DOI 10.21504/10962/405456
- Description: This mixed methods study explored the impact of the use of a visualisation approach on the pedagogy of eight teacher participants who were involved in the Rundu Campus Fraction Project (RCFP). The aim of this study was to determine the extent to which participants incorporated visualisation processes in the pedagogy of fractions, in view of their exposure to visualisation activities in the RCFP. Since fractions are difficult to teach and learn, visualisation was considered as an alternative approach to the pedagogy of fractions because it presents learners with opportunities to improve their proportional and spatial reasoning. This study was founded on the premise that the incorporation of both verbal and nonverbal cues can enhance the teaching and learning of fractions rather than the use of a single cue. Hence, the two theories underpinning this study are the Dual Coding Theory and the Constructivist Theory. While the Dual Coding Theory advocates for the use of verbal and nonverbal codes, the Constructivist theory states that meaningful learning occurs when learners are presented with opportunities to construct their own knowledge. Thus, the two codes are intertwined. In other words, the active construction of knowledge among learners is aided by using constructivist teaching approaches through the incorporation of both verbal and nonverbal codes. Although this study was predominantly qualitative, quantitative methods were also used in the data collection process. A questionnaire was administered to identify teacher participants for this study, based on their teaching orientations. Their views on best practices in mathematics classrooms in general and the incorporation of visualisation processes in particular, were instrumental in the selection of participants for this study. In addition, observations and semi-structured interviews were also used as research methods. Twenty-five lesson samples were video recorded, transcribed and analysed using both qualitative and quantitative methods. Moreover, each of the eight participants was exposed to a set of pre- and post-observation interviews during which they were expected to express their views on the selection, incorporation and impact of visualisation processes on the teaching of fractions. Data sets from all three instruments were analysed using both quantitative and qualitative methods. The findings indicate that the RCFP had an impact on the teaching strategies employed by the participants as they all incorporated visualisation processes into their teaching to some extent. In some lessons, the visual code was effectively blended into the verbal code while in others, the purpose of and connection between the two codes was not evident. Hence, although all the participants embraced the incorporation of visualisation in the pedagogy of mathematics, some of them struggled to find its rightful position in the teaching of fractions. The findings suggest that despite the participants’ eagerness to use visualisation in their fraction lessons, some of them did not have adequate knowledge to successfully merge it with the conventional verbal code. Thus, for the integration of visuals to be impactful, it should be carefully merged in the teaching of fractions by taking into account various factors. , Thesis (PhD) -- Faculty of Education, Education, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Ausiku, Charity Makwiliro
- Date: 2022-10-14
- Subjects: Mathematics Study and teaching (Elementary) Namibia , Fractions Study and teaching (Elementary) Namibia , Visualization , Visual learning , Dual-coding hypothesis , Constructivism (Education) Namibia
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/405456 , vital:70173 , DOI 10.21504/10962/405456
- Description: This mixed methods study explored the impact of the use of a visualisation approach on the pedagogy of eight teacher participants who were involved in the Rundu Campus Fraction Project (RCFP). The aim of this study was to determine the extent to which participants incorporated visualisation processes in the pedagogy of fractions, in view of their exposure to visualisation activities in the RCFP. Since fractions are difficult to teach and learn, visualisation was considered as an alternative approach to the pedagogy of fractions because it presents learners with opportunities to improve their proportional and spatial reasoning. This study was founded on the premise that the incorporation of both verbal and nonverbal cues can enhance the teaching and learning of fractions rather than the use of a single cue. Hence, the two theories underpinning this study are the Dual Coding Theory and the Constructivist Theory. While the Dual Coding Theory advocates for the use of verbal and nonverbal codes, the Constructivist theory states that meaningful learning occurs when learners are presented with opportunities to construct their own knowledge. Thus, the two codes are intertwined. In other words, the active construction of knowledge among learners is aided by using constructivist teaching approaches through the incorporation of both verbal and nonverbal codes. Although this study was predominantly qualitative, quantitative methods were also used in the data collection process. A questionnaire was administered to identify teacher participants for this study, based on their teaching orientations. Their views on best practices in mathematics classrooms in general and the incorporation of visualisation processes in particular, were instrumental in the selection of participants for this study. In addition, observations and semi-structured interviews were also used as research methods. Twenty-five lesson samples were video recorded, transcribed and analysed using both qualitative and quantitative methods. Moreover, each of the eight participants was exposed to a set of pre- and post-observation interviews during which they were expected to express their views on the selection, incorporation and impact of visualisation processes on the teaching of fractions. Data sets from all three instruments were analysed using both quantitative and qualitative methods. The findings indicate that the RCFP had an impact on the teaching strategies employed by the participants as they all incorporated visualisation processes into their teaching to some extent. In some lessons, the visual code was effectively blended into the verbal code while in others, the purpose of and connection between the two codes was not evident. Hence, although all the participants embraced the incorporation of visualisation in the pedagogy of mathematics, some of them struggled to find its rightful position in the teaching of fractions. The findings suggest that despite the participants’ eagerness to use visualisation in their fraction lessons, some of them did not have adequate knowledge to successfully merge it with the conventional verbal code. Thus, for the integration of visuals to be impactful, it should be carefully merged in the teaching of fractions by taking into account various factors. , Thesis (PhD) -- Faculty of Education, Education, 2022
- Full Text:
- Date Issued: 2022-10-14
Biosynthesis of silver nanoparticles from Acacia mearnsii De Wild stem bark and its antinociceptive properties
- Avoseh, Opeyemi N, Oyedeji, Opeoluwa O, Aremu, Olukayode, Nkeh-Chungag, Benedicta N, Songca, Sandile P, Oyedeji, Adebola Omowunmi, Mohan, Sneha, Oluwafemi, Oluwatobi S
- Authors: Avoseh, Opeyemi N , Oyedeji, Opeoluwa O , Aremu, Olukayode , Nkeh-Chungag, Benedicta N , Songca, Sandile P , Oyedeji, Adebola Omowunmi , Mohan, Sneha , Oluwafemi, Oluwatobi S
- Date: 2017
- Subjects: Metal nanoparticles , Acacia mearnsii , Nociceptive pain
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/1528 , vital:37774 , https://doi.org/10.1080/17518253.2017.1287310
- Description: The biosynthesis of silver nanoparticles (Ag-NPs) using the hydrosol extract of the dry stem bark of Acacia mearnsii as reducing and capping agents, and their antinociceptive properties are hereby reported. By varying the temperature and reaction time, the temporal evolution of the optical and morphological properties of the as-synthesized material was investigated. The NPs were characterized by UV–visible absorption spectroscopy, transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive x-ray spectroscopy (EDS) and x-ray diffractometry (XRD) The optical analyses show that the position of the maximum surface plasmon resonance (SPR) peak is red-shifted as the reaction temperature decreased. The TEM micrographs show that the as-synthesized Ag-NPs are spherical while the X-ray diffraction shows that the material is highly crystalline with face-centered cubic structures. The anti-inflammatory efficacy, analyzed by the formalin model, indicates that the as-synthesized Ag-NPs are very effective, with an inhibition rate of about 76%.
- Full Text:
- Date Issued: 2017
- Authors: Avoseh, Opeyemi N , Oyedeji, Opeoluwa O , Aremu, Olukayode , Nkeh-Chungag, Benedicta N , Songca, Sandile P , Oyedeji, Adebola Omowunmi , Mohan, Sneha , Oluwafemi, Oluwatobi S
- Date: 2017
- Subjects: Metal nanoparticles , Acacia mearnsii , Nociceptive pain
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/1528 , vital:37774 , https://doi.org/10.1080/17518253.2017.1287310
- Description: The biosynthesis of silver nanoparticles (Ag-NPs) using the hydrosol extract of the dry stem bark of Acacia mearnsii as reducing and capping agents, and their antinociceptive properties are hereby reported. By varying the temperature and reaction time, the temporal evolution of the optical and morphological properties of the as-synthesized material was investigated. The NPs were characterized by UV–visible absorption spectroscopy, transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive x-ray spectroscopy (EDS) and x-ray diffractometry (XRD) The optical analyses show that the position of the maximum surface plasmon resonance (SPR) peak is red-shifted as the reaction temperature decreased. The TEM micrographs show that the as-synthesized Ag-NPs are spherical while the X-ray diffraction shows that the material is highly crystalline with face-centered cubic structures. The anti-inflammatory efficacy, analyzed by the formalin model, indicates that the as-synthesized Ag-NPs are very effective, with an inhibition rate of about 76%.
- Full Text:
- Date Issued: 2017
Comprehensive data on the mechanical properties and biodegradation profile of polylactide composites developed for hard tissue repairs
- Aworinde, Abraham K, Adeosun, Samson O, Oyawale, Festus A, Emagbetere, Eyere, Ishola, Felix A, Olatunji, Obafemi, Akinlab, Stephen, Oyedepo, Sunday O, Ajayi, Oluseyi O, Akinlabi, Esther T
- Authors: Aworinde, Abraham K , Adeosun, Samson O , Oyawale, Festus A , Emagbetere, Eyere , Ishola, Felix A , Olatunji, Obafemi , Akinlab, Stephen , Oyedepo, Sunday O , Ajayi, Oluseyi O , Akinlabi, Esther T
- Date: 2020
- Subjects: Regeneration (Biology) , Vickers microhardness , Melt-blending technique
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/3149 , vital:43158 , https://doi.org/10.1016/j.dib.2020.106107
- Description: Africa, the ancestral home of all modern humans, is the most informative continent for understanding the human genome and its contribution to complex disease. To better understand the genetics of schizophrenia, we studied the illness in the Xhosa population of South Africa, recruiting 909 cases and 917 age-, gender-, and residence-matched controls. Individuals with schizophrenia were significantly more likely than controls to harbor private, severely damaging mutations in genes that are critical to synaptic function, including neural circuitry mediated by the neurotransmitters glutamine, γ-aminobutyric acid, and dopamine. Schizophrenia is genetically highly heterogeneous, involving severe ultrarare mutations in genes that are critical to synaptic plasticity. The depth of genetic variation in Africa revealed this relationship with a moderate sample size and informed our understanding of the genetics of schizophrenia worldwide.
- Full Text:
- Date Issued: 2020
- Authors: Aworinde, Abraham K , Adeosun, Samson O , Oyawale, Festus A , Emagbetere, Eyere , Ishola, Felix A , Olatunji, Obafemi , Akinlab, Stephen , Oyedepo, Sunday O , Ajayi, Oluseyi O , Akinlabi, Esther T
- Date: 2020
- Subjects: Regeneration (Biology) , Vickers microhardness , Melt-blending technique
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/3149 , vital:43158 , https://doi.org/10.1016/j.dib.2020.106107
- Description: Africa, the ancestral home of all modern humans, is the most informative continent for understanding the human genome and its contribution to complex disease. To better understand the genetics of schizophrenia, we studied the illness in the Xhosa population of South Africa, recruiting 909 cases and 917 age-, gender-, and residence-matched controls. Individuals with schizophrenia were significantly more likely than controls to harbor private, severely damaging mutations in genes that are critical to synaptic function, including neural circuitry mediated by the neurotransmitters glutamine, γ-aminobutyric acid, and dopamine. Schizophrenia is genetically highly heterogeneous, involving severe ultrarare mutations in genes that are critical to synaptic plasticity. The depth of genetic variation in Africa revealed this relationship with a moderate sample size and informed our understanding of the genetics of schizophrenia worldwide.
- Full Text:
- Date Issued: 2020
Effects of climatic variability on maize productivity in South Africa from 1937-2018
- Awum Awum, Rudin https://orcid.org/ 0000-0002-8740-6163
- Authors: Awum Awum, Rudin https://orcid.org/ 0000-0002-8740-6163
- Date: 2022-03
- Subjects: Crops and climate , Climatic changes
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/21410 , vital:48576
- Description: Climate is an important factor in agricultural production. The world is facing climate change and variability, which result in high temperatures, low rainfall patterns, shortage of water and persistent droughts. Climate change poses a significant threat to South Africa’s water resources, food security, health, infrastructure, ecosystem services and biodiversity. Negative impacts of climate variability on agriculture, especially on maize the staple crop, will worsen the food security status of the nation as most of South Africa’s maize crop is produced in summer and highly depends on rainfall. This study attempted to assess the impact of climate on maize production in South Africa using secondary time series data for the period 1937 to 2018. Rainfall and temperature were used as proxies for climate variability. The Granger Causality Model was used to examine the causal linkages between climatic variables (temperature or rainfall) and maize output in South Africa for the study period. The major outcome of the analysis was that there is a two-way causal relationship between maize production and temperature. The results also indicated that there is uni-directional causality between maize yield and rainfall. Furthermore, the Variance Decomposition Model was used to forecast the relationship between climatic elements and maize production in South Africa. The result showed that all variables have an effect on maize yield, with temperature having the least effect. The last objective of the study was to profile the maize output trend for the period from 1937 to 2018. The main findings from the analysis indicate that maize production in South Africa has a general upward slope. The study recommends that the government should intensify the provision of irrigation systems for the farmers in the most vulnerable areas to mitigate the climate change. Government should also embark on massive campaigns using a variety of media to create the needed public awareness on climate change and its impact on food security. , Thesis (MSc) -- Faculty of Science and Agriculture, 2022
- Full Text:
- Date Issued: 2022-03
- Authors: Awum Awum, Rudin https://orcid.org/ 0000-0002-8740-6163
- Date: 2022-03
- Subjects: Crops and climate , Climatic changes
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/21410 , vital:48576
- Description: Climate is an important factor in agricultural production. The world is facing climate change and variability, which result in high temperatures, low rainfall patterns, shortage of water and persistent droughts. Climate change poses a significant threat to South Africa’s water resources, food security, health, infrastructure, ecosystem services and biodiversity. Negative impacts of climate variability on agriculture, especially on maize the staple crop, will worsen the food security status of the nation as most of South Africa’s maize crop is produced in summer and highly depends on rainfall. This study attempted to assess the impact of climate on maize production in South Africa using secondary time series data for the period 1937 to 2018. Rainfall and temperature were used as proxies for climate variability. The Granger Causality Model was used to examine the causal linkages between climatic variables (temperature or rainfall) and maize output in South Africa for the study period. The major outcome of the analysis was that there is a two-way causal relationship between maize production and temperature. The results also indicated that there is uni-directional causality between maize yield and rainfall. Furthermore, the Variance Decomposition Model was used to forecast the relationship between climatic elements and maize production in South Africa. The result showed that all variables have an effect on maize yield, with temperature having the least effect. The last objective of the study was to profile the maize output trend for the period from 1937 to 2018. The main findings from the analysis indicate that maize production in South Africa has a general upward slope. The study recommends that the government should intensify the provision of irrigation systems for the farmers in the most vulnerable areas to mitigate the climate change. Government should also embark on massive campaigns using a variety of media to create the needed public awareness on climate change and its impact on food security. , Thesis (MSc) -- Faculty of Science and Agriculture, 2022
- Full Text:
- Date Issued: 2022-03
Impact of press freedom on reportage of corruption in the Nigerian oil and gas industry : a comparative content analysis of four Nigerian Newspapers
- Ayodeji-Falade, Monisola Bolajoko
- Authors: Ayodeji-Falade, Monisola Bolajoko
- Date: 2021-10
- Subjects: Newspapers -- Nigeria , Freedom of the press , Mass media -- Nigeria
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/21805 , vital:51787
- Description: A free press is pivotal to eradication of corruption in the society as the press remains the most powerful channel of communication that cut across all publics. Thus, this study seeks to evaluate the impact of press freedom on reportage of corruption in the oil and gas industry through a content analysis of four Nigerian newspapers (The Punch, Vanguard, Guardian and Nigerian Tribune). The study adopted a mixed research method involving both quantitative and qualitative approaches. Quantitative data were collected and analysed through content analysis of the selected newspapers while the qualitative data collected through interview of the respective newspaper correspondents were analysed using thematic analysis. The study revealed that 534 stories were published on corruption in the Nigerian oil and gas sector by all the newspapers within the study period (July 2018-June 2019), with the Punch having the highest magnitude of stories (n = 196, 36.70percent) while Nigerian Tribune had the highest number of stories reported on its front and back pages (n = 143, 92.25percent). However, Guardian had the highest number of full-paged stories (n = 15, 20percent) whereas the Punch and Nigerian Tribune adopted the widest range of publication formats with news being the most dominant format employed by all the dailies (n = 462, 86.52percent). Although, all the newspapers employed more episodic frame (n = 432, 80.89percent) than thematic frame (n = 93,17.41percent), framing analysis revealed oil theft, vandalism, alleged-fraud, environmental consequences and economic consequences as the major frames used in the coverage of stories on corruption in the Nigerian oil and gas industry. Thematic analysis showed that the newspaper correspondents did not have access to adequate information on corruption in the sector while journalists in the country are still being subjected to intimidation, arrest and imprisonment. These findings suggest that the selected newspapers gave prominence to reportage of corruption in the oil and gas sector in country, which implies that the newspapers are fulfilling their agenda-setting roles and social responsibility in the society. Nevertheless, the level of press freedom in Nigeria has partly affected the reportage of corruption in the oil and gas sector of the country as this has restricted the use of investigative reporting occasioned by the lack of access to classified information on corruption and envisaged harm by potential sources and journalists. Nevertheless, this study proposes an anticorruption-media model, which focuses on the significance of the media as an anticorruption agent in a developing country. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2021
- Full Text:
- Date Issued: 2021-10
- Authors: Ayodeji-Falade, Monisola Bolajoko
- Date: 2021-10
- Subjects: Newspapers -- Nigeria , Freedom of the press , Mass media -- Nigeria
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/21805 , vital:51787
- Description: A free press is pivotal to eradication of corruption in the society as the press remains the most powerful channel of communication that cut across all publics. Thus, this study seeks to evaluate the impact of press freedom on reportage of corruption in the oil and gas industry through a content analysis of four Nigerian newspapers (The Punch, Vanguard, Guardian and Nigerian Tribune). The study adopted a mixed research method involving both quantitative and qualitative approaches. Quantitative data were collected and analysed through content analysis of the selected newspapers while the qualitative data collected through interview of the respective newspaper correspondents were analysed using thematic analysis. The study revealed that 534 stories were published on corruption in the Nigerian oil and gas sector by all the newspapers within the study period (July 2018-June 2019), with the Punch having the highest magnitude of stories (n = 196, 36.70percent) while Nigerian Tribune had the highest number of stories reported on its front and back pages (n = 143, 92.25percent). However, Guardian had the highest number of full-paged stories (n = 15, 20percent) whereas the Punch and Nigerian Tribune adopted the widest range of publication formats with news being the most dominant format employed by all the dailies (n = 462, 86.52percent). Although, all the newspapers employed more episodic frame (n = 432, 80.89percent) than thematic frame (n = 93,17.41percent), framing analysis revealed oil theft, vandalism, alleged-fraud, environmental consequences and economic consequences as the major frames used in the coverage of stories on corruption in the Nigerian oil and gas industry. Thematic analysis showed that the newspaper correspondents did not have access to adequate information on corruption in the sector while journalists in the country are still being subjected to intimidation, arrest and imprisonment. These findings suggest that the selected newspapers gave prominence to reportage of corruption in the oil and gas sector in country, which implies that the newspapers are fulfilling their agenda-setting roles and social responsibility in the society. Nevertheless, the level of press freedom in Nigeria has partly affected the reportage of corruption in the oil and gas sector of the country as this has restricted the use of investigative reporting occasioned by the lack of access to classified information on corruption and envisaged harm by potential sources and journalists. Nevertheless, this study proposes an anticorruption-media model, which focuses on the significance of the media as an anticorruption agent in a developing country. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2021
- Full Text:
- Date Issued: 2021-10
Antibiotics combination therapy option for the control of antimicrobial-resistant non-cholera causing Vibrio species recovered from environmental niches of Eastern Cape, South Africa
- Authors: Ayodele, Oluwakemi Victoria
- Date: 2021-04
- Subjects: Drug resistance in microorganisms , Vibrio cholerae
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20396 , vital:45661
- Description: Increased rate of antibiotic resistance (AR) poses a serious threat with a resultant notion of a possible end of the antibiotics era, making it a problem of concern to public health and a great implication on the world economy and human society. Despite many approaches developed to curb this menace, antibiotics resistance is still a challenge worldwide. This has made the use of combined therapy as one of the options in many cases. This study was conducted to assess antibiotics combination therapy as an option for the control of antimicrobial-resistant non-cholera causing Vibrio species that were recovered from the environment in the Eastern Cape, South Africa. Two hundred and twenty-eight Vibrio species were recovered from the environment in the Province, and these were deposited in the archive of AEMREG. PCR was used to identify target Vibrio species. Disc diffusion method was used to evaluate the antibiotic susceptibility profile of the confirmed isolates against 11 antibiotics commonly used against infections. MIC and MBC were determined using antibiotics (imipenem, tetracycline, and nalidixic acid) that high resistance was discovered. Checkerboard assay was used to carry out antibiotics combination assay, and the FICI was calculated. Rate of kill was also determined using ½ × MIC, 1 × MIC, and 2 × MIC concentrations of the combined antibiotics at 2 hr intervals. One hundred of the isolates were confirmed to be Vibrio parahaemolyticus, 82 were Vibrio vulnificus and 46 were Vibrio fluvialis. Twenty-two (22) percent of the Vibrio parahaemolyticus isolates showed resistance against tetracycline and their resistance against other antimicrobials is as follows; nalidixic acid (16 percent), ampicillin (14 percent), cefotaxime (14 percent), chloramphenicol (12 percent) and amikacin (11 percent). For Vibrio vulnificus, prevalence of resistance was as follows: imipenem (40 percent), tetracycline (22 percent), ampicillin (18 percent), meropenem (15 percent), and chloramphenicol (11 percent). Vibrio fluvialis showed the following resistance profile: nalidixic acid (28 percent), tetracycline (28percent), ampicillin (20 percent), chloramphenicol (15 percent), amikacin (11 percent) and cefotaxime (11 percent). About 38 multiple antibiotic resistance phenotypes (MARP) were recorded in all species that were evaluated. About 23 percent were resistant to over 3 antibiotics used. The multiple antibiotic resistant indices (MARI) ranged between 0.3 and 0.8. MIC and MBC were carried against isolates that were resistant to the two most common antibiotics tested. MIC and MBC were determined in the following order: tetracycline and nalidixic acid at concentrations ranging from 16 μg/ml to 1024 μg/ml for Vibrio parahaemolyticus and 32 μg/ml to 2048 μg/ml for Vibrio fluvialis. Also, the MIC and MBC of imipenem and tetracycline at concentrations ranging from 8 μg/ml to 256 μg/ml for Vibrio vulnificus were determined. Antibiotics combination therapy was carried out and synergistic activity was observed in 3 of the 16 resistant V. parahaemolyticus isolates, 3 of the16 resistant V. vulnificus isolates and 2 of the 13 resistant V. fluvialis isolates. Antagonism was not observed across all the drug combinations. Rate of kill was also determined and at 6 hr exposure time, the highest concentration (2 × MIC) exhibited bactericidal effect across all three Vibrio species. The result derived in this research, therefore, propose that combination therapy is a promising solution to antimicrobial resistance in Vibrio species. , Thesis (MSc) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Ayodele, Oluwakemi Victoria
- Date: 2021-04
- Subjects: Drug resistance in microorganisms , Vibrio cholerae
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20396 , vital:45661
- Description: Increased rate of antibiotic resistance (AR) poses a serious threat with a resultant notion of a possible end of the antibiotics era, making it a problem of concern to public health and a great implication on the world economy and human society. Despite many approaches developed to curb this menace, antibiotics resistance is still a challenge worldwide. This has made the use of combined therapy as one of the options in many cases. This study was conducted to assess antibiotics combination therapy as an option for the control of antimicrobial-resistant non-cholera causing Vibrio species that were recovered from the environment in the Eastern Cape, South Africa. Two hundred and twenty-eight Vibrio species were recovered from the environment in the Province, and these were deposited in the archive of AEMREG. PCR was used to identify target Vibrio species. Disc diffusion method was used to evaluate the antibiotic susceptibility profile of the confirmed isolates against 11 antibiotics commonly used against infections. MIC and MBC were determined using antibiotics (imipenem, tetracycline, and nalidixic acid) that high resistance was discovered. Checkerboard assay was used to carry out antibiotics combination assay, and the FICI was calculated. Rate of kill was also determined using ½ × MIC, 1 × MIC, and 2 × MIC concentrations of the combined antibiotics at 2 hr intervals. One hundred of the isolates were confirmed to be Vibrio parahaemolyticus, 82 were Vibrio vulnificus and 46 were Vibrio fluvialis. Twenty-two (22) percent of the Vibrio parahaemolyticus isolates showed resistance against tetracycline and their resistance against other antimicrobials is as follows; nalidixic acid (16 percent), ampicillin (14 percent), cefotaxime (14 percent), chloramphenicol (12 percent) and amikacin (11 percent). For Vibrio vulnificus, prevalence of resistance was as follows: imipenem (40 percent), tetracycline (22 percent), ampicillin (18 percent), meropenem (15 percent), and chloramphenicol (11 percent). Vibrio fluvialis showed the following resistance profile: nalidixic acid (28 percent), tetracycline (28percent), ampicillin (20 percent), chloramphenicol (15 percent), amikacin (11 percent) and cefotaxime (11 percent). About 38 multiple antibiotic resistance phenotypes (MARP) were recorded in all species that were evaluated. About 23 percent were resistant to over 3 antibiotics used. The multiple antibiotic resistant indices (MARI) ranged between 0.3 and 0.8. MIC and MBC were carried against isolates that were resistant to the two most common antibiotics tested. MIC and MBC were determined in the following order: tetracycline and nalidixic acid at concentrations ranging from 16 μg/ml to 1024 μg/ml for Vibrio parahaemolyticus and 32 μg/ml to 2048 μg/ml for Vibrio fluvialis. Also, the MIC and MBC of imipenem and tetracycline at concentrations ranging from 8 μg/ml to 256 μg/ml for Vibrio vulnificus were determined. Antibiotics combination therapy was carried out and synergistic activity was observed in 3 of the 16 resistant V. parahaemolyticus isolates, 3 of the16 resistant V. vulnificus isolates and 2 of the 13 resistant V. fluvialis isolates. Antagonism was not observed across all the drug combinations. Rate of kill was also determined and at 6 hr exposure time, the highest concentration (2 × MIC) exhibited bactericidal effect across all three Vibrio species. The result derived in this research, therefore, propose that combination therapy is a promising solution to antimicrobial resistance in Vibrio species. , Thesis (MSc) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-04
An in vitro investigation of novel quinolone derivatives on selected pharmacological targets for diabetes mellitus and associated complications
- Authors: Ayodele, Omobolanle Opeyemi
- Date: 2023-03-29
- Subjects: Diabetes , Hyperglycemia , Quinolone antibacterial agents , Cardiovascular system Diseases , Diabetes Alternative treatment , In vitro experiment
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/409813 , vital:70632
- Description: Diabetes mellitus (DM) is a group of endocrine and metabolic disorders characterised and identified by the presence of hyperglycaemia over a long period and, to an extent, accompanied by hyperlipidaemia. CVD has been reported to be the leading cause of mortality in patients with DM. Several antidiabetic agents are available for managing DM, but these agents are not for curative therapy and present with undesirable side effects. In addition, these agents become less effective as the patient's condition progresses to complete beta-cell failure. Therefore, developing newer antidiabetic agents with minimal undesirable side effects, prolonged efficacy and protection against the development of DM complications are necessary. This study was conducted to identify potential novel antidiabetic agents with cardiovascular-protective activity. The compounds of interest for the study were quinolone derivatives since quinolones have been reported to have an antihyperglycaemic effect. , Thesis (MSc) -- Faculty of Pharmacy, 2023
- Full Text:
- Date Issued: 2023-03-29
- Authors: Ayodele, Omobolanle Opeyemi
- Date: 2023-03-29
- Subjects: Diabetes , Hyperglycemia , Quinolone antibacterial agents , Cardiovascular system Diseases , Diabetes Alternative treatment , In vitro experiment
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/409813 , vital:70632
- Description: Diabetes mellitus (DM) is a group of endocrine and metabolic disorders characterised and identified by the presence of hyperglycaemia over a long period and, to an extent, accompanied by hyperlipidaemia. CVD has been reported to be the leading cause of mortality in patients with DM. Several antidiabetic agents are available for managing DM, but these agents are not for curative therapy and present with undesirable side effects. In addition, these agents become less effective as the patient's condition progresses to complete beta-cell failure. Therefore, developing newer antidiabetic agents with minimal undesirable side effects, prolonged efficacy and protection against the development of DM complications are necessary. This study was conducted to identify potential novel antidiabetic agents with cardiovascular-protective activity. The compounds of interest for the study were quinolone derivatives since quinolones have been reported to have an antihyperglycaemic effect. , Thesis (MSc) -- Faculty of Pharmacy, 2023
- Full Text:
- Date Issued: 2023-03-29
Forest resources income, poverty and income inequality: evidence from rural households in South-western Nigeria.
- Authors: Azeez, Fatai Abiola
- Date: 2017
- Subjects: Poverty--Nigeria http://id.loc.gov/authorities/subjects/sh2010107919 , Rural poor--Nigeria , Income distribution--Nigeria
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/19454 , vital:43119
- Description: This thesis explores economic contributions of forest resources in relation to rural households’ welfare and inequality as well as forest resources management. The thesis consists of an introductory chapter, study locations, literature review on major concepts of the study and findings on different forest extraction activities impacts on rural households livelihood in South-western region Nigeria, which make up the rest of the thesis chapters. , Thesis (PhD) (Agric Econs) -- University of Fort Hare, 2017
- Full Text:
- Date Issued: 2017
- Authors: Azeez, Fatai Abiola
- Date: 2017
- Subjects: Poverty--Nigeria http://id.loc.gov/authorities/subjects/sh2010107919 , Rural poor--Nigeria , Income distribution--Nigeria
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/19454 , vital:43119
- Description: This thesis explores economic contributions of forest resources in relation to rural households’ welfare and inequality as well as forest resources management. The thesis consists of an introductory chapter, study locations, literature review on major concepts of the study and findings on different forest extraction activities impacts on rural households livelihood in South-western region Nigeria, which make up the rest of the thesis chapters. , Thesis (PhD) (Agric Econs) -- University of Fort Hare, 2017
- Full Text:
- Date Issued: 2017
Synthesis, characterization and host-guest complexes of supramolecular assemblies based on calixarenes and cucurbiturils
- Authors: Baa, Ebenezer
- Date: 2022-10-14
- Subjects: Supramolecular chemistry , Calixarenes , Cucurbiturils , Metal-organic frameworks , Macrocyclic compounds , Drug delivery systems
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/365621 , vital:65765 , DOI https://doi.org/10.21504/10962/365621
- Description: The field of supramolecular chemistry has grown large and wide in both deepness of understanding, range of topics covered and scope and applications. Supramolecular self-assemblies are facilitated by a wide range of non-covalent intra and inter molecular interactions that range from hydrogen bonding to π-interaction and van der Waals. Macrocyclic compounds such as cucurbiturils and calixarenes have emerged as important classes of compounds with excellent potential of forming supramolecular assemblies. The porous nature of these compounds enables them to form host-guest supramolecular complexes stabilized by diverse range of non-covalent interactions. Furthermore, these compounds contain donor atoms capable of forming bonds with metal ions to yield metal complexes with interesting porous characteristics that deviate from their traditional hydrophobic cavity. The versatile nature of the resulting pores imply that they can accommodate diverse types of guests. This work explores the synthesis and characterization of a host of calixarenes and cucurbiturils. Self-assembly of these macrocycles with various metal ions results to the formation of porous metal organic framework (MOF) complexes. Four new calixarene typed compounds obtained from aromatic aldehydes and twenty-six cucurbituril metal complexes are reported. These macrocylces and their metal complexes also form supramolecular complexes with DMSO, methanol, isoniazid hydrochloride and ciprofloxacin hydrochlorides through either self-assembly, mechanochemistry and exposure to solvent vapors. The bulk materials have been characterized using nuclear magnetic resonance spectroscopy (NMR), Fourier transformed infrared spectroscopy (FTIR), powder and single crystal diffraction techniques and thermal studies thermogravimetric analysis (TGA) and differential thermal calorimetry (DSC). Data obtained from this study reveals that calixarenes can form supramolecular complexes with a frequently used laboratory solvents with BN22 showing appreciable selectivity for DMSO sorption from a solvent mixture. These compounds also form supramolecular complexes with drug molecules such as isoniazid and ciprofloxacin. Furthermore, the data reveals that choice of synthetic route of supramolecular ensembles dictates if the guest drug molecule will occupy the intrinsic or extrinsic pores of cucurbituril complexes. Biological studies on the obtained complexes reveal that the cucurbituril complexes are non-cytotoxic while the calixarenes show antibacterial activity against Escherichia coli and Staphylococcus aureus. Additionally, the study showed that ciprofloxacin can be successfully released from a calixarene host in a simulated body fluid although the host was also found to cross the dialysis membrane. The results of this study are important in that; - they can be exploited and developed in the selective sorption of certain guests and - that they can be used in the development of drug delivery systems that play a dual role of delivery and therapeutic activity. , Thesis (PhD) -- Faculty of Science, Chemistry, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Baa, Ebenezer
- Date: 2022-10-14
- Subjects: Supramolecular chemistry , Calixarenes , Cucurbiturils , Metal-organic frameworks , Macrocyclic compounds , Drug delivery systems
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/365621 , vital:65765 , DOI https://doi.org/10.21504/10962/365621
- Description: The field of supramolecular chemistry has grown large and wide in both deepness of understanding, range of topics covered and scope and applications. Supramolecular self-assemblies are facilitated by a wide range of non-covalent intra and inter molecular interactions that range from hydrogen bonding to π-interaction and van der Waals. Macrocyclic compounds such as cucurbiturils and calixarenes have emerged as important classes of compounds with excellent potential of forming supramolecular assemblies. The porous nature of these compounds enables them to form host-guest supramolecular complexes stabilized by diverse range of non-covalent interactions. Furthermore, these compounds contain donor atoms capable of forming bonds with metal ions to yield metal complexes with interesting porous characteristics that deviate from their traditional hydrophobic cavity. The versatile nature of the resulting pores imply that they can accommodate diverse types of guests. This work explores the synthesis and characterization of a host of calixarenes and cucurbiturils. Self-assembly of these macrocycles with various metal ions results to the formation of porous metal organic framework (MOF) complexes. Four new calixarene typed compounds obtained from aromatic aldehydes and twenty-six cucurbituril metal complexes are reported. These macrocylces and their metal complexes also form supramolecular complexes with DMSO, methanol, isoniazid hydrochloride and ciprofloxacin hydrochlorides through either self-assembly, mechanochemistry and exposure to solvent vapors. The bulk materials have been characterized using nuclear magnetic resonance spectroscopy (NMR), Fourier transformed infrared spectroscopy (FTIR), powder and single crystal diffraction techniques and thermal studies thermogravimetric analysis (TGA) and differential thermal calorimetry (DSC). Data obtained from this study reveals that calixarenes can form supramolecular complexes with a frequently used laboratory solvents with BN22 showing appreciable selectivity for DMSO sorption from a solvent mixture. These compounds also form supramolecular complexes with drug molecules such as isoniazid and ciprofloxacin. Furthermore, the data reveals that choice of synthetic route of supramolecular ensembles dictates if the guest drug molecule will occupy the intrinsic or extrinsic pores of cucurbituril complexes. Biological studies on the obtained complexes reveal that the cucurbituril complexes are non-cytotoxic while the calixarenes show antibacterial activity against Escherichia coli and Staphylococcus aureus. Additionally, the study showed that ciprofloxacin can be successfully released from a calixarene host in a simulated body fluid although the host was also found to cross the dialysis membrane. The results of this study are important in that; - they can be exploited and developed in the selective sorption of certain guests and - that they can be used in the development of drug delivery systems that play a dual role of delivery and therapeutic activity. , Thesis (PhD) -- Faculty of Science, Chemistry, 2022
- Full Text:
- Date Issued: 2022-10-14
Contract compliance in procuring and disposing entities (PDES) in state departments in Uganda: subtitle if needed. If no subtitle follow instructions in manual
- Authors: Babirye, Hamidah
- Date: 2021-04
- Subjects: Communication , Records -- Management , Public contracts -- Uganda
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/50933 , vital:43173
- Description: Contract compliance has continuously played a vital role in the development of nations globally. It is important, because it enhances the efficiency and success of projects; ensures value for money; mitigates risks and saves a considerable amount of time and resources. Despite its importance, projects continue to fail due to poor communication, untimely deliveries, poor quality deliveries and the lack of a suitable compliance environment. This study helped to address the aforementioned challenges by creating an enabling environment for contract compliance in procuring and disposing entities (PDEs) in state departments in Uganda. The purpose of this study was to determine the enabling factors necessary for contract compliance and how it can be effectively used to assist PDEs in the Ugandan context. This purpose was achieved through a qualitative research approach that provided insights into the need for contract compliance among PDEs and the perceptions thereof; the contract compliance processes; challenges associated with contract compliance and the factors to be considered when creating an enabling environment for contract compliance. Data was gathered from telephonic interviews with twenty one participants and focus group discussions via the Zoom online platform with eight participants, bringing the total number of participants to twenty nine. Participants included auditors, accounting officers, heads of finance departments, heads of procurement departments and procurement officers. Data was collected using an interview guide and analysed by means of content and thematic analyses. A conceptual framework for creating a suitable environment for contract compliance in PDEs was developed. Findings indicate that the critical factors for creating an enabling environment include: communication; reporting; records management; institutional structure; compliance checks; enforcement; a legal and regulatory framework; and evaluation. Other factors include: stakeholder involvement; contract management; funding; openness; ethical orientation; and capacity building. The proposed conceptual framework serves as a valuable resource for researchers and practitioners, especially those involved in public procurement. , Thesis (DPhil) -- Faculty of Business and Economic Sciences, Business Management, 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Babirye, Hamidah
- Date: 2021-04
- Subjects: Communication , Records -- Management , Public contracts -- Uganda
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/50933 , vital:43173
- Description: Contract compliance has continuously played a vital role in the development of nations globally. It is important, because it enhances the efficiency and success of projects; ensures value for money; mitigates risks and saves a considerable amount of time and resources. Despite its importance, projects continue to fail due to poor communication, untimely deliveries, poor quality deliveries and the lack of a suitable compliance environment. This study helped to address the aforementioned challenges by creating an enabling environment for contract compliance in procuring and disposing entities (PDEs) in state departments in Uganda. The purpose of this study was to determine the enabling factors necessary for contract compliance and how it can be effectively used to assist PDEs in the Ugandan context. This purpose was achieved through a qualitative research approach that provided insights into the need for contract compliance among PDEs and the perceptions thereof; the contract compliance processes; challenges associated with contract compliance and the factors to be considered when creating an enabling environment for contract compliance. Data was gathered from telephonic interviews with twenty one participants and focus group discussions via the Zoom online platform with eight participants, bringing the total number of participants to twenty nine. Participants included auditors, accounting officers, heads of finance departments, heads of procurement departments and procurement officers. Data was collected using an interview guide and analysed by means of content and thematic analyses. A conceptual framework for creating a suitable environment for contract compliance in PDEs was developed. Findings indicate that the critical factors for creating an enabling environment include: communication; reporting; records management; institutional structure; compliance checks; enforcement; a legal and regulatory framework; and evaluation. Other factors include: stakeholder involvement; contract management; funding; openness; ethical orientation; and capacity building. The proposed conceptual framework serves as a valuable resource for researchers and practitioners, especially those involved in public procurement. , Thesis (DPhil) -- Faculty of Business and Economic Sciences, Business Management, 2021
- Full Text:
- Date Issued: 2021-04
Thien-2-yl substituted chlorins as photosensitizers for photodynamic therapy and photodynamic antimicrobial chemotherapy
- Babu, Balaji, Sindelo, Azole, Mack, John, Nyokong, Tebello
- Authors: Babu, Balaji , Sindelo, Azole , Mack, John , Nyokong, Tebello
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/190578 , vital:45007 , xlink:href="https://doi.org/10.1016/j.dyepig.2020.108886"
- Description: The synthesis and characterization of meso-tetra(thien-2-yl)chlorin (1) and meso-tetra(5-bromothien-2-yl)chlorin (2) is reported. These dyes have red-shifted absorption maxima compared to those of the analogous meso-tetraphenylchlorin (3). 1 and 2 have Q bands at 660 and 664 nm, respectively, singlet oxygen quantum yields of 0.60 and 0.64 and exhibit good photostability. The triplet states were found to have lifetimes of 8.6 μs in N2 purged DMF. Time-dependent cellular uptake of chlorins reached a maximum in MCF-7 cancer cells after 12 h. Upon irradiation with a Thorlabs M660L3 LED (280 mW cm−2), 2 exhibited better photocytotoxicity with an IC50 value of 2.7 μM against MCF-7 cells. The 2ʹ,7ʹ-dichlorodihydrofluorescein diacetate (DCFDA) assay provided evidence for intracellular generation of reactive oxygen species. Photodynamic inactivation of bacteria by the chlorins was also studied. 2 exhibits better activity with log reduction values of 7.42 and 8.34 towards Staphylococcus aureus and Escherichia coli, respectively, under illumination for 60 min at 660 nm with a Thorlabs M660L3 LED (280 mW cm−2). These results demonstrate that 2 is a promising candidate for future in vivo experiments and merits further in-depth investigation.
- Full Text:
- Date Issued: 2021
- Authors: Babu, Balaji , Sindelo, Azole , Mack, John , Nyokong, Tebello
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/190578 , vital:45007 , xlink:href="https://doi.org/10.1016/j.dyepig.2020.108886"
- Description: The synthesis and characterization of meso-tetra(thien-2-yl)chlorin (1) and meso-tetra(5-bromothien-2-yl)chlorin (2) is reported. These dyes have red-shifted absorption maxima compared to those of the analogous meso-tetraphenylchlorin (3). 1 and 2 have Q bands at 660 and 664 nm, respectively, singlet oxygen quantum yields of 0.60 and 0.64 and exhibit good photostability. The triplet states were found to have lifetimes of 8.6 μs in N2 purged DMF. Time-dependent cellular uptake of chlorins reached a maximum in MCF-7 cancer cells after 12 h. Upon irradiation with a Thorlabs M660L3 LED (280 mW cm−2), 2 exhibited better photocytotoxicity with an IC50 value of 2.7 μM against MCF-7 cells. The 2ʹ,7ʹ-dichlorodihydrofluorescein diacetate (DCFDA) assay provided evidence for intracellular generation of reactive oxygen species. Photodynamic inactivation of bacteria by the chlorins was also studied. 2 exhibits better activity with log reduction values of 7.42 and 8.34 towards Staphylococcus aureus and Escherichia coli, respectively, under illumination for 60 min at 660 nm with a Thorlabs M660L3 LED (280 mW cm−2). These results demonstrate that 2 is a promising candidate for future in vivo experiments and merits further in-depth investigation.
- Full Text:
- Date Issued: 2021