Studies on an autolysin produced by clostridium acetobutylicum
- Authors: Webster, Jocelyn Rowena
- Date: 1981
- Subjects: Clostridium acetobutylicum , Autolysis , Bacteriocins , Proteins -- Synthesis , DNA -- Synthesis , RNA -- Synthesis
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3893 , http://hdl.handle.net/10962/d1003724
- Description: An extracellular bacteriocin-like substance produced by Clostridium acetobutylicum was detected during studies on an industrial fermentation process. The bacteriocin-like substance was not inducible by either ultraviolet light or mitomycin C, and its production was not associated with the induction of a protease. Studies on the mode of action of the bacteriocin-like substance indicated that it had no significant effect on DNA, RNA, or protein synthesis, and it did not cause the loss of intracellular ATP. However, the bacteriocin-like substance was able to lyse SDS-treated cells and cell walls of C. acetobutylicum and was identified as an autolysin. Some of the characteristics of this extracellular autolysin were determined, and after purification it was shown to be a glycoprotein with a molecular weight of 28 000.
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- Date Issued: 1981
Foreign reference products in the registration of generic medicines in South Africa a case study
- Authors: Hwengwere, Eldinah
- Date: 2012
- Subjects: Generic drugs -- Law and legislation -- South Africa Case studies Generic drugs -- South Africa Case studies Drugs -- Law and legislation -- South Africa Case studies Pharmacy -- Law and legislation -- South Africa Case studies
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:3762 , http://hdl.handle.net/10962/d1003240
- Description: Introduction: Due to the increase in healthcare costs, generic medicines have been adopted for used in both developed and developing countries. When a generic or ‘multisource interchangeable medicine’ is to be registered, studies that prove that the generic is equivalent to the Innovator Product (IP) are used. The generic medicine is required to prove that it will mirror the IP in terms of safety, quality and efficacy and, in South Africa, the Medicines Control Council (MCC) ensures that generic medicines meet these requirements. Generic medicines may be registered using bioequivalence data obtained from comparison with a domestic reference product (usually the local innovator product) or in certain cases, a foreign reference product (FRP). The bioequivalence data can either be from in vivo or in vitro studies. The MCC guidelines require that for modified release preparations, in vivo bioequivalence studies are done for approval of registration; the exception being if a proportionally higher dose has already been registered. No information is currently given to prescribers and dispensers or to the public about whether a generic product was registered against a foreign or domestic reference product. Aims and Objectives: 1.) To determine the number of generic medicines in a predetermined sample registered using a FRP as comparator and to document the transparency of pharmaceutical companies when approached to disclose information regarding the registration of these products. 2.) To describe and document the use of the Promotion of Access to Information Act (Act 2 of 2000) [PAIA] from the perspective of a ‘layperson’ in the context of medicines’ regulation, in both private and public bodies. Methods: 20 modified release and Biopharmaceutics Classification System (BCS) class IV products were selected from the ‘generics dictionary’ – a commercial publication – and letters were sent to the manufacturers of the products requesting information about the tests done to prove equivalence and whether they were performed against a domestic or foreign reference product. The same information was also requested from the MCC. The requests were all made using the Promotion of Access to Information Act (PAIA). Results: Nine companies were represented by the 20 products chosen. Information was obtained about thirteen products. Ten of these products were registered using FRPs. Four products were registered based only on comparative dissolution studies. Four companies provided the requested information, two companies responded by refusing the requests and three did not respond at all. The MCC refused the request for information even after an internal appeal was lodged. Conclusions: The Promotion of Access to information Act was unsuccessful in obtaining information from the public body, and partly successful in obtaining it from the private bodies. While the title of the Act seems to indicate that the Act can be used to obtain information as such, it only provides for access to specified records. The MCC and the pharmaceutical companies involved in the study were under no obligation to provide the information as the request had not complied with PAIA requirements. The use of FRPs for registration is a reality in the pharmaceutical industry in South Africa. Neither the public nor healthcare professionals who prescribe medicines or who are involved in dispensing generic medicines as substitutes are aware of whether or not a FRP has been used to register a generic. Interchangeability cannot necessarily be guaranteed if the reference product was not proven equivalent to the local innovator product. It is debatable as to whether or not this information would be of any particular benefit to members of the public. Prescribers may choose to write ‘no substitution’ on their prescriptions if they were unconvinced that an FRP is acceptable. This could have consequences for healthcare costs. Dispensers are the most vulnerable in South Africa as they are obliged by law to substitute generic medicines when innovator medicines have been prescribed. Dispensers’ views on the acceptability of the use of FRPs can be seen as irrelevant. In the end, as this study demonstrates, the only option in the present situation is to rely entirely on the MCC’s rigour in assessing applications for registration of generic medicines.
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- Date Issued: 2012
Localizing selected endocytosis protein candidates in Plasmodium falciparum using GFP-tagged fusion constructs
- Authors: Basson, Travis
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/2680 , vital:20316
- Description: Malaria is a mosquito-borne infectious disease caused by several obligate intracellular protozoan parasites in the Plasmodium genus, with Plasmodium falciparum causing the most widespread cases and malaria deaths. In 2013 there were approximately 190 million cases of the disease and between 584,000 and 855,000 deaths. It is essential to identify novel drug targets and develop novel drug candidates due to the increase in resistance of P. falciparum parasites to the current arsenal of antimalarial drugs. Endocytosis is an essential process in eukaryotic cells in which the external environment is internalized by the cell in order to obtain various particles from the extracellular space. This extracellular cytoplasm is internalized in membrane-bound invaginations at the plasma membrane. During the blood stage of malaria infection, the parasite requires nutrients from the host red blood cell. To obtain these nutrients, the parasite internalizes haemoglobin in large amounts and degrades it in an acidic, lysosome-like organelle, known as the digestive vacuole. Whilst the exact molecular mechanism of malaria parasite endocytosis is not yet fully understood, a number of proteins have been suggested to be involved. The most expedient approach in identifying candidate endocytosis proteins is to investigate parasite homologues of proteins known to be involved in endocytosis in mammalian cells. The three proteins selected for investigation in this study were the P. falciparum homologues of coronin, dynamin 2, and μ4. The coding sequences for the candidate endocytosis proteins were amplified by PCR and cloned into the pARL2-GFP expression vector. P. falciparum 3D7 parasites were transfected with these vectors and the episomal expression of full-length GFP-tagged fusion protein was confirmed by Western blot analysis using commercially available anti-GFP antibodies. Microscopic analysis of live parasites using fluorescence and confocal microscopy was used to determine the localization of the candidate endocytosis proteins. Coronin appeared to display diffuse cytoplasmic GFP localization during the trophozoite stage, arguing against a role in endocytosis. However, distinct localization during the schizont stage at what appears to be the inner membrane complex was observed. Coronin is thus likely required to coordinate the formation of the actin network between the merozoite IMC and the plasma membrane on which the glideosome is dependant for generating the motile forces required for the merozoite motility and invasion of RBCs. Dynamin 2 displayed localization at three potential locii: the parasite periphery (plasma membrane), punctuate regions within the cytoplasm (potentially at membrane bound organelles) and at the parasite food vacuole. The data suggested that dynamin 2 is involved in endocytosis and membrane trafficking in a similar manner to classical dynamins, potentially as a vesicle scission molecule at the plasma membrane, mediating vesicle formation at the food vacuole to recycle membrane to the plasma membrane, and possibly mitochondria organelle division. μ4 displayed transient localization, cycling between cytosolic localization, and localization to distinct regions at the plasma membrane and the food vacuole. Localization of Pfμ4 to the plasma membrane is indicative of a role for μ4 as a part of an adaptor protein (AP) complex which may be responsible for recruitment of clathrin to initiate endocytosis in a manner similar to mammalian AP-2. As was observed with PfDYN2, Pfμ4 localizes to the FV, which suggests that Pfμ4 forms part of a coat complex that mediates the formation of vesicles that recycle membrane from the FV to the parasite plasma membrane. This study showed that expressing proteins as full-length GFP-tagged fusion constructs is an effective approach in the early stages of determining the localization and function of P. falciparum proteins in vitro, and distinguishing between candidates that have a potential role in endocytosis and those that are unlikely to do so.
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- Date Issued: 2016
Developed teacher leadership in a township high school : an interpretive case study
- Authors: John, Daisy Mary
- Date: 2015
- Subjects: Educational leadership -- South Africa -- Eastern Cape , School management and organization -- South Africa -- Eastern Cape , Teacher participation in administration -- South Africa -- Eastern Cape , Teacher effectiveness -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:2052 , http://hdl.handle.net/10962/d1018548
- Description: South Africa’s future success depends on a number of national priorities, amongst them the transformation of its education system. Education is the best route to follow to alleviate poverty and many other social ills. One way to overcome some of the complex challenges and crises that we face in South African schools is to pay attention to issues of leading and leadership, including the leadership of teachers. This study is done with the hope that research into teacher leadership will be one of the answers to the crisis in education. It should become a beacon of hope for all educationists who passionately want progress in the youth of South Africa. What better way than to ‘Awaken the Sleeping Giant’ of teacher leadership, borrowing the term from Katzenmeyer and Moller (2009). This study was designed as a case study, the purpose of which was to find out about the enactment of teacher leadership in an Eastern Cape township high school as well as the enhancing and hindering factors to this enactment. This study was done as a replication study of a similar study done by a group of 11Master’s students at the University of KwaZulu-Natal in 2010. Similar to the original study, this case study was located within the interpretive paradigm and drew on school profiling, survey questionnaires, a focus group interview, selfreflective journals and individual interviews for its methods of data collection. The study was framed by distributed leadership while Grant’s (2008; 2012) Model of teacher leadership was adopted as the analytical tool. It emerged from the data that the three teacher leaders, my primary participants, exhibited teacher leadership across all four zones of Grant’s (2008) Model. The first zone was leadership in the classroom where all three teacher leaders showed leadership to varying degrees. Zones Two to Four are about leadership beyond the classroom into the school and beyond. In Zone Two, the zone where teachers work with each other and the learners outside the classroom, substantial levels of leadership were enacted by the three teacher leaders. Zone Three, where leadership is exhibited in whole-school development, the three primary participants showed distinct leadership qualities as well. The fourth zone, which is about interaction with neighbouring schools, also revealed that all three teacher leaders demonstrated active leadership on a regular basis. Findings further revealed that there were only a few inhibiting factors to the leadership of teachers at the case study school, including limited resources and infrastructure as well as insufficient support and acknowledgement from the relevant stakeholders when leadership initiatives were made, either successfully or otherwise. However, the enhancing factors superseded the inhibiting factors. A functional committee culture guided by a shared vision existed in the case study school together with an ethos of trust which enabled the staff to work collaboratively. Though there was certainly room for improvement in leadership practices at this case study school, the enactment of teacher leadership in this school illustrated a strong case of ‘developed’ teacher leadership (Muijs& Harris, 2007) within a dispersed leadership framing (Gunter, 2005)
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- Date Issued: 2015
Creating a new declaration of rights : a critical reconstruction of earth jurisprudence's global legislative framework
- Authors: Lenferna, Georges Alexandre
- Date: 2013
- Subjects: Universal Declaration , Rights , Earth , Environment , Ethics , Environmental law, International -- Research , Environmental law, International -- Philosophy , Environmental ethics -- Research , Nature conservation -- Law and legislation -- Research , Jurisprudence -- Research , Law -- Philosophy
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: vital:2704 , http://hdl.handle.net/10962/d1001979
- Description: This thesis aims to critique the Universal Declaration of the Rights of Mother Earth and its underlying moral justification in order to provide a stronger and improved version of both. In Chapter 1 I explore what sort of moral justification is necessary to establish the Universal Declaration on firm grounds and explore its relation to environmental ethics and rights discourse. I argue that a non-anthropocentric perspective is necessary to justify the Universal Declaration’s rights. In Chapter 2 I explore the underlying justification of the Universal Declaration as discovered in the works of Cormac Cullinan and Father Thomas Berry. I argue that their ethical framework is indeterminate, has many ambiguities and uncertainties, and, among other problems, it does not provide a clear action-guiding framework. In Chapter 3 I develop an alternative justification for the Universal Declaration. I argue against many predominant moral theories, that in light of our best scientific and moral understanding we should expand the realm of moral concern to include all living beings, a moral theory I call Life’s Imperative. In Chapter 4 I illustrate that Life’s Imperative is a much stronger, more coherent justification for the Universal Declaration, one that coheres with both our best understanding of the natural world and our relation to it, and to an environmental ethic reflective of that relationship. Unfortunately many of the weaknesses in the current implicit justification of the Universal Declaration have also led to it enshrining rights that are themselves problematic. In order to address these issues, I revise its rights to accord with the stronger justification that I established in Chapter 3. The end result of doing so is a revised version of the Universal Declaration
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- Date Issued: 2013
Cosmological structure formation using spectral methods
- Authors: Funcke, Michelle
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/2969 , vital:20348
- Description: Numerical simulations are becoming an increasingly important tool for understanding the growth and development of structure in the universe. Common practice is to discretize the space-time using physical variables. The discreteness is embodied by considering the dynamical variables as fields on a fixed spatial and time resolution, or by constructing the matter fields by a large number of particles which interact gravitationally (N-body methods). Recognizing that the physical quantities of interest are related to the spectrum of perturbations, we propose an alternate discretization in the frequency domain, using standard spectral methods. This approach is further aided by periodic boundary conditions which allows a straightforward decomposition of variables in a Fourier basis. Fixed resources require a high-frequency cut-off which lead to aliasing effects in non-linear equations, such as the ones considered here. This thesis describes the implementation of a 3D cosmological model based on Newtonian hydrodynamic equations in an expanding background. Initial data is constructed as a spectrum of perturbations, and evolved in the frequency domain using a pseudo-spectral evolution scheme and an explicit Runge-Kutta time integrator. The code is found to converge for both linear and non-linear evolutions, and the convergence rate is determined. The correct growth rates expected from analytical calculations are recovered in the linear case. In the non-linear model, we observe close correspondence with linear growth and are able to monitor the growth on features associated with the non-linearity. High-frequency aliasing effects were evident in the non-linear evolutions, leading to a study of two potential resolutions to this problem: a boxcar filter which adheres to“Orszag’s two thirds rule” and an exponential window function, the exponential filter suggested by Hou and Li [1], and a shifted version of the exponential filter suggested, which has the potential to alleviate high frequency- ripples resulting from the Gibbs’ phenomenon. We found that the filters were somewhat successful at reducing aliasing effects but that the Gibbs’ phenomenon could not be entirely removed by the choice of filters.
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- Date Issued: 2016
The interface of history and fiction in Russel Brownlee’s Garden of the plagues, Ingrid Winterbach’s To hell With Cronjé, and Etienne van Heerden’s The long silence of Mario Salviati
- Authors: Wyrill, Beth Alexandra
- Date: 2014
- Subjects: Brownlee, Russel -- Criticism and interpretation , Winterbach, Ingrid -- Criticism and interpretation , Van Heerden, Etienne, 1954- -- Criticism and interpretation , South African fiction (English) -- History and criticism , South African fiction (English) -- 20th century -- History and criticism , African fiction (English) -- 21st century -- History and criticism , Brownlee, Russel -- Garden of the plagues , Winterbach, Ingrid -- Niggie -- English , Van Heerden, Etienne, 1954- -- Swye van Mario Salviati -- English , Historical fiction -- History and criticism , Magic realism (Literature)
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2323 , http://hdl.handle.net/10962/d1015517
- Description: Both historiographical and literary practices have undergone revision in recent years in attempting to address the inheritance of nineteenth-century realism. Since the object of realist stylistics, employed in both the writing of fiction and history, is to render authorship authoritative or even invisible, the ideological import of these narratives is often such that the constructedness of the historical record and its absences are veiled. In developments beginning in the 1980s with the advent of ‘New Historicism’ and with the emergence of postmodern literary techniques, the interface of literature and history became of seminal importance, since both were now credited as being products of narrative and discourse, and hence, to varying degrees, of the literary imagination. This movement intersects interestingly with developments in postcolonial studies, since it is the voices of the marginalized and disempowered colonized peoples that are routinely co-opted and excised from nineteenth-century realist histories. These concerns are now being fully explored in the literature of the contemporary post-transitional South African moment, since authors in this country seemingly now feel freed up to look back to histories that precede the immediate traumas of apartheid. The concern, in relation to apartheid developments but also on a broader universal scale, is this: if history is viewed as perpetual emergences of modernities, then one of the great absences in the record is the historical determinants of any given epistemology. The attempt to recreate such an epistemological genealogy is thus simultaneously postcolonial, historiographical, and literary. Russel Brownlee’s Garden of the Plagues (2005), Ingrid Winterbach’s To Hell with Cronjé (2010), and Etienne van Heerden’s The Long Silence of Mario Salviati (2002) attempt to bridge this gap in the recorded sensibilities of any historical moment by representing a ‘lived experience’ of the past, and in the process imaginatively recreating the cultural, historical and psychological locations of the proponents of an emerging modernity. This study concerns itself with the ways in which these authors address the influence of realist historiography through the use of literary innovations that allow for the departure from realist stylistics. Most commonly, all three authors draw on forms of magic realism, but multiple refigurings and recombinations of notions of temporality, narrative, and characterization likewise work to defamiliarize the once stable discourse of history.
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- Date Issued: 2014
Environmental youth clubs in Namibia : what role do, could or should they play in environmental education?
- Authors: Botma, Connie
- Date: 2000
- Subjects: Environmental education -- Namibia Environmental education -- Study and teaching -- Namibia Youth -- Societies and clubs Youth -- Namibia
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1519 , http://hdl.handle.net/10962/d1003401
- Description: Although the existence of wildlife clubs in Africa dates back to the start of the environmental movement in the 1970s, youth involvement through environmental clubs only commenced in Namibia in 1992. I became involved with the clubs in 1995 when I was employed by the Rossing Foundation Environmental Education Project to encourage, support and coordinate environmental clubs in Namibia. During the last three years the number of Namibian clubs has increased from 20 to ±85, and they are now established in most geographical regions of the country. During my involvement with the clubs I became increasingly interested in the philosophical underpinnings of youth movements like clubs and started questioning what we could expect from the youth and what could be achieved through the clubs. One of my main concerns was whether youth could make a significant improvement to the quality of their lives and their environment through these clubs. The aim of my research was therefore to describe and reflect critically on the role of environmental youth clubs in environmental education in Namibia. My study was guided by a socially critical orientation which emphasises the construction of meaning through social dialogue and critical reflection. I chose an interpretative research strategy and generated data mainly through semi-structured interviews, participant observation, a focus-group discussion and a workshop. Due to the focus of the research I purposefully selected the sample of existing youth clubs to be included in the study. The iterative strategy of gathering and interpreting data in successive cycles allowed for continuous reflection throughout the research process. It also allowed me to identify key patterns and trends in analysing and interpreting the data. The study findings suggest that environmental clubs do playa role in learning about environmental issues; in developing personal and social identity, confidence and a sense of purpose in society; in establishing new and supportive relationships between teachers and learners and with other community resourde people; in creating opportunities and enabling exposure to diverse learning environments, options and alternatives; and ih fostering the orientation and skills needed to effect meaningful d1'inges in the environment. The findings also suggest that environmental clubs could make a significant contribution to environmental education, providing that they incorporate a socially critical orientation, gain greater recognition from significant adults and education officials, collaborate with other projects and organisations, and use guidelines of models such as the action research framework to ensure relevant and effective action projects. The main challenges to environmental clubs in Namibia include changing perceptions that youth do not have much to contribute; improving relationships between clubs, schools and communities; dealing with the tension between the possible disempowering effect of central control and the need for more formalised structures in order to gain official recognition; and developing strategies to ensure the clubs' sustainability in the future.
- Full Text:
- Date Issued: 2000
Exploring the influence of a multiliteracies approach on Grade 11 Physical Sciences learners' sense making and dispositions towards graphs of motion
- Authors: Mwiiyale, Laina Natangwe
- Date: 2017
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/17605 , vital:22264
- Description: Namibian students perform poorly in Physical Sciences and the Physics component in particular (DNEA, 2013). The Namibian Senior Secondary Certificate (NSSC) Examiner's report (DNEA, 2014) also reveals that many Physical Science learners have difficulties demonstrating an understanding of basic physics required for working with kinematic graphs (graphical representation of motion). Kinematics is an important tool in understanding the motion of objects - whether translational, oscillatory or circular. In kinematics, the relationships between distance, displacement, speed, velocity or acceleration and time are represented in graphs of motion. In teaching the topic, using graphs can be an alternative to the use of abstract formulas, or formulas can be used along with graphical representations to facilitate student understanding (Behzak, 2006). This study explored the influence of the multiliteracies approach on grade 11 Physical Science learners' dispositions and sense making towards graphs of motion. The intervention being investigated is informed by the Pedagogy of Multiliteracies (PoM) framework by Cazden et al., (1996) with the focus on overt instruction, situated practice, critical framing and transformed practice using semiotic patterns of meaning, in conjunction with Vygotsky's (1978) social constructivism theory - particularly, its notion of mediation. This action research study employed the interpretive paradigm. Data were collected using a pre-test, stimulated recall interviews, lesson observations, a post-test and learners' reflections. Data were coded and the codes then categorized into different themes in order to answer the research questions. The findings of this study were that learners are better able to make sense of graphs of motions when a PoM approach is employed. Their dispositions towards graphs of motion also improved as a result of the PoM intervention, due to it enabling a better understanding of kinematics concepts. This study also contributed to the professional development of the researcher, particularly in terms of it contributing to a broader understanding of the research and possible usefulness of semiotic mediation in science education. Implications of the study include the possibility of including the PoM approach in science teacher education and training programme curricula.
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- Date Issued: 2017
An analysis of the reporting on poverty and foreign aid in Sub-Saharan Africa before and during the current global economic crisis, in BBC online (Texts)
- Authors: Achu, Stella
- Date: 2009
- Subjects: Economic assistance -- Africa, Sub-Saharan , Poverty -- Africa, Sub-Saharan , Financial crises , Africa, Sub-Saharan -- Economic conditions
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:8371 , http://hdl.handle.net/10948/1257 , Economic assistance -- Africa, Sub-Saharan , Poverty -- Africa, Sub-Saharan , Financial crises , Africa, Sub-Saharan -- Economic conditions
- Description: Since 1929, the world economy has not encountered any financial crisis as severe as the case of the Great Depression, until 2007 when the fall of stock markets and the collapse of large financial institutions in the United States resulted in a worldwide recession. According to an IMF report, and as a result of the direct impact of the crisis, advanced economies such as those of the United States and Europe are suffering from a systemic banking crisis with economic output expected to contract by over 1 ¾ % in 2009. (Bourdin 2009:2) Although the crisis erupted in the United States, the effects quickly spread to countries worldwide. However, its effects are said to be more devastating for the poorest regions in the world including Sub-Saharan Africa. During the last few years, prior to the crisis, many Sub-Saharan African countries had enjoyed a growth rate of over 5%. This was partly as a result of sound economic policies and increased external support in the form of debt relief and higher inflows from economically powerful countries in the West. However, with the current financial crisis, wealthy nations have been forced to concentrate on sustaining their own economy. As a result, amongst changes like tighter immigration policies, skyrocketing oil prices and food prices, foreign aid is being withdrawn. (ibid 2009:3) According to foreign media reports, donor governments and the G8 are no longer as committed to aid as before the crisis. This research paper examines the evolution of aid to Africa in view of various contexts through a broad historical economic and political economy overview, and finally corroborates these observations with a discourse analysis of a sample of BBC online articles. The research project thus investigates in this last section, the BBC’s representation of poverty and aid in Sub-Saharan Africa before and during the current global economic crisis.
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- Date Issued: 2009
Mantle xenoliths from the Abrahamskraal kimberlite : a craton-margin geotherm
- Authors: Nowicki, Thomas Edward
- Date: 1991
- Subjects: Kimberlite , Kimberlite -- Inclusions
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4898 , http://hdl.handle.net/10962/d1001557
- Description: The Abrahamskraal kimberlite pipe (group I) occurs approximately 5 km to the south-west of the geophysically defined margin of the Kaapvaal craton in the central Cape Province, and contains a variety of crustal and mantle xenoliths. This study focusses on xenoliths of deep-seated origin (mantle and lower-crustal), and in particular on garnet-orthopyroxene bearing assemblages which are amenable to thermobarometric techniques. Four major types of deep-seated xenolith have been identified, i.e. peridotites, dunites , eclogites, and garnet pyroxenites. The petrographic features and mineral compositions of these xenoliths are described . Pressures and temperatures of equilibration have been calculated primarily using the garnet-orthopyroxene thermometer of Harley (1984), and the Al-in-enstatite barometer of Nickel and Green (1985). The peridotites are coarse-textured (Harte, 1977), magnesium -rich rocks, and are typical examples of the common type I peridotites which generally dominate mantle xenolith suites in kimberlites. Garnet peridotite xenoliths define a geotherm which lies along a typical theoretical conductive geothermal gradient for shield areas (Pollack and Chapman, 1977), and which extends to a maximum pressure of 41 kb (~130 km). Comparison of the Abrahamskraal geotherm with that constructed for the northern Lesotho xenolith suite (calculated using the same thermobarometer couple), suggests that the lithosphere at the Namaqua /Kaapvaal boundary is not significantly thinner or hotter than that underlying the craton. Modelling of the craton boundary under the constraints provided by the Abrahamskraal geotherm, and by the distribution of diamond-bearing kimberlites in southern Africa, indicates that the Abrahamskraal kimberlite has sampled relatively thick, cool , Namaqua lithosphere. It is suggested that, in terms of diamond distribution, the age and magmatic history of the Namaqua lithosphere is of greater significance than its thickness. Two varieties of dunite occur at Abrahamskraal. Coarse-textured dunites with Mg-rich olivine compositions similar to those of the peridotitic olivines, probably originated by similar (but perhaps more extreme) processes to those which formed the peridotites. A finer-grained and relatively Fe-rich variety of dunite may represent ultramafic cumulates formed by fractionation of basic or ultrabasic magmas within the mantle. Two varieties of eclogite have been distinguished. Coarse-grained eclogites which yield relatively high temperature estimates, are believed to have originated from depths similar to those determined for the garnet peridotites, i.e. from the lower lithosphere. A distinctly finer grained variety of eclogite, yields significantly lower temperatures which may be based on frozen-in equilibria. A maximum depth of approximately 87 km (~ 27 kb) has been estimated for these xenoliths, but they may have originated from significantly shallower (possibly lower-crustal) levels. The garnet pyroxenite xenoliths are generally orthopyroxene-rich rocks which contain varying amounts of garnet (8 to 33 %) and clinopyroxene (0 to 64 %). Textural features indicate that the garnet and possibly some of the clinopyroxene has exsolved from an originally A l -rich orthopyroxene. The rocks are significantly more Fe-rich than the peridotite xenoliths, and their constituent minerals show a wide range of Mg/Mg+Fe ratios. The pressure-temperature array defined by the garnet pyroxenites is approximately isothermal, and spans a depth range from approximately 30 to 95 km. It deviates strongly (to higher temperatures) from the ambient geothermal gradient at the time of kimberlite emplacement, as inferred from the garnet peridotite xenoliths. The pressures and temperatures calculated for the garnet pyroxenites are based on mineral equilibria which are believed to have been frozen-in during cooling from an intial hightemperature (probably molten) state. Qualitative modelling of possible cooling paths in pressure-temperature-composition space, indicates that the apparent depth range displayed by the garnet pyroxenites, approximates the true depth range over which these rocks were emplaced. However, the apparent pressures calculated from core compositions are significantly lower than the true pressures at which the original rocks formed . The garnet pyroxenite xenoliths appear to represent a major, possibly Namaqua age (~1000-1400 Ma), magmatic event involving the emplacement of large amounts of mafic magma over a significant depth range in the shallow upper mantle
- Full Text:
- Date Issued: 1991
The design of an office headquarters for SAMSUNG in the foreshore, Cape Town
- Authors: Wiese, Andre
- Date: 2019
- Subjects: Office buildings -- South Africa -- Cape Town , Office layout -- South Africa -- Cape Town Office buildings -- Design and construction Office buildings -- Planning
- Language: English
- Type: Thesis , Masters , MArch
- Identifier: http://hdl.handle.net/10948/40413 , vital:36159
- Description: This treatise developed through an interest in 21st century office buildings and most particularly, their impact on productivity, employee wellness and corporate culture. The conventional office of the mid-20th century disregarded employee health and well-being and was geared toward increasing productivity and production. The retrofitting of these buildings is very costly, and it is almost impossible to ensure compliance with modern-day environmental and efficiency standards to ultimately create a good office environment conducive to productivity and employee well-being. The nature of office has shifted to a more collaborative, socially interactive, open and flexible working environment because of the mobility technology offers the workplace. The current office building typology is concerned with the health and well-being of employees, active design, sustainability and environmental awareness. The treatise takes a qualitative research approach that is exploratory in nature and through careful analysis and interpretation, site constraints and informants are identified that inform the design of an office headquarters for Samsung. Pure research is based on the readings of Richard Sennett, Jane Jacobs, Stephen Kellert and Judith Heerwagen. An understanding is developed around factors that positively impact employee health and well-being in the workplace. Research determines that social interaction, human nature connectivity and the designed environment significantly impact the health and well-being of office user. Social interaction is scalable from the urban network to internal workspaces and is essential to create a seamless connection between the office environment and immediate urban context to stimulate serendipitous moments of interaction. The design of a Samsung Headquarters in Foreshore Cape Town uses Building Information Management (BIM) among other strategies to respond to its immediate environmental conditions and to create an environment conducive to the health and well-being of the office user and effectively increase productivity. The design is situated along a prominent pedestrian corridor that connects the CBD to the waterfront.
- Full Text:
- Date Issued: 2019
The dionysian in performance reclaiming the female transgressive performing body
- Authors: Solomon, Zanne
- Date: 2012
- Subjects: Dionysia , Feminism and theater , Human body in literature , Performance art , Performing arts , Body image in women , Self-perception in women , Human body -- Social aspects
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2148 , http://hdl.handle.net/10962/d1002380
- Description: In this thesis I investigate the theoretical or philosophical notion/archetype of the Dionysian in relation to the transgressive female body in performance. I do so through 1) an investigation into the theories behind the Dionysian and the transgressive; 2) an examination of the performative practice of the transgressive female body; and 3) a personal exploration of the theatrical practice. 1) In the first chapter I introduce and thoroughly explore the archetypal concept of the Dionysian, and identify its significance because of its intrinsic association with the transgressive. I associate it with its oppositional force, the Apollonian, which is similarly significant because it is through the Dionysian disruption of the Apollonian from which the very notion of the transgressive springs. Through a review of Camille Paglia's seminal text on the subject of the Dionysian¹, this chapter provides a historical, mythological and theoretical context for the schism between the two archetypal aesthetics, starting from the description of the mythology of the ancient Greek gods, Dionysus and Apollo, and unpacks the transgressive nature of the Dionysian. Drawing on concurring theories of Friedrich Nietzsche and Julia Kristeva, as well as Hans Thies-Lehmann's writings on post-dramatic theatre², Chapter One attempts to firmly establish the inherent link between the Dionysian and theatre and performance, as well as the Dionysian and the transgressive, and provide a thorough theoretical framework for the rest of the thesis. 2) The second chapter investigates the work of two female performance artists³ who (re)present⁴ their bodies as transgressive in performance, namely Marina Abramovic and Karen Finley. It critically examines specific performance works of theirs, and through this examination it explores how they (re)present their bodies as transgressive in performance, and why they do so. This chapter furthermore establishes the connection between the transgressive female performing body, as (re)presented by Abramovic and Finley, and the Dionysian. In so doing it explores how they negotiate this ancient aesthetic or practice in a contemporary performance context. I believe that these performance artists are in fact striving to celebrate and reclaim the Dionysian within their work, and I attempt to establish this within this chapter. 3) The third chapter of this thesis analyses my own practical exploration of the transgressive female body in performance in a piece entitled Bleeding Mermaid (2008). It examines this exploration in the context of the theory of the Dionysian, as well as investigating how and why I (re)presented my body as transgressive in the performance. The analysis furthermore questions how I understand my work on the (re)presentation of the transgressive female body in relation to, and within the context of, Finley and Abramovic's work on the same subject. Through this investigation, I aim to establish a link between the Dionysian and the transgressive female performing body; and investigate the motivation(s) behind the (re)presentation of the transgressive female body in performance. I hope to open up a pathway to the reclamation of the Dionysian, both in performance practice and research. ¹Paglia, Camille. Sexual Personae: Art and Decadence from Nefertiti to Emily Dickinson. England: Penguin Books, 1990. ²Lehmann, Hans-Thies. Postdramatic Theatre. Trans. and Intro. Karen Jürs-Munby. London and New York: Routledge, 2006. ³Performance Art began around the 1960s in Europe and America. It is performance with a sense of immediacy – in that it is hard to replicate as it interacts with each unique audience – it is thus effectively a fresh/new experience each time. It breaks the boundaries of traditional theatre (form, structure, venue, time etc) and is often shocking or provocative in nature. It mixed the aesthetics of theatre and art, often taking place in installation settings. Performance Art has developed and morphed throughout the years, and is also referred to as Live Art in Britain. A performance artist is someone who produces performance art. It is possible that Performance Art no longer exists/is possible because it no longer shocks or affects the audience. ⁴My use of the brackets in (re)presented/(re)present throughout this thesis is because I would like to make simultaneous reference to the words/connotations of "presentation" and "representation", without being bound to the connotations of illusion/falseness/non-reality as is associated with the word "representation" (in opposition to the concept of the "real"), and thus be left only with the one-dimensional approach/meaning of "presentation".
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- Date Issued: 2012
An examination of how organisational policy and news professionalism are negotiated in a newsroom: a case study of Zimbabwe's Financial gazette
- Authors: Gandari, Jonathan
- Date: 2010
- Subjects: Financial gazette Journalism -- Zimbabwe Journalism -- Political aspects -- Zimbabwe Journalistic ethics Journalists -- Zimbabwe Newspapers -- Zimbabwe Mass media -- Political aspects -- Zimbabwe Mass media -- Law and legislation -- Zimbabwe
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3430 , http://hdl.handle.net/10962/d1002884
- Description: The construction of journalistic professionalism in Zimbabwe has stirred debate among scholars. Critics have argued that professionalism has been compromised by the stifling media laws in Zimbabwe as well as the extra legal measures the state has enforced to control the press. Some have also argued that a new kind of journalism must be emerging in the Zimbabwean newsroom as journalism try to cope with the political and economic pressures bedeviling the country. Much of this criticism however, has not been based on close interrogation of professionalism from the perspective of the journalists in any particular newsroom. It is against this background that this study examines the constructions of professionalism at the Financial Gazette. In particular it explores the meaning of professionalism through interrogating the journalistic practices the journalists consider during the process of news production in the context of overwhelming state power. In undertaking this examination, the study draws primarily on qualitative research methods, particularly observation and multi-layered individual in-depth interviews. As the study demonstrates, the interrogation of professionalism from the perspective of newsroom practices uncovers the complex manner in which professionalism is negotiated in the Gazette’s newsroom located in a country undergoing transition in Democracy. The study establishes that when measured against normative canons of journalistic professionalism the Gazette is deviating from such tenets as public service and watchdog journalism. As the study indicates, perhaps unbeknown to the respondents, the ruling ZANU PF party hegemony is reproduced at the Gazette through choice of news values such as sovereignty and patriotism all euphemisms for ruling party‘s slogans.
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- Date Issued: 2010
An investigation into the principals' leadership roles in selected schools in the Ohangwena Region in Namibia: case study
- Authors: Shitana, Silas Shituleipo
- Date: 2012
- Subjects: School management and organization -- Namibia -- Ohangwena School principals -- Namibia -- Ohangwena Educational leadership -- Namibia -- Ohangwena Educational change -- Namibia -- Ohangwena Management -- Employee participation -- Namibia -- Ohangwena
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1614 , http://hdl.handle.net/10962/d1003496
- Description: School leadership in Namibia over past centuries was characterized by ‘top down’ administration and typically proceeded without participation of those involved other than the principals who were the sole decision makers. The notion of school leadership through teamwork (team leadership) in Namibia was formalized after the advent of democracy in 1990 and the subsequent reorganization of the education system. The notion of team leadership is embedded in theories that stress participation, teamwork and distributed leadership. It is against this background that this study sought to investigate the current understandings of school leadership and application of team leadership among principals in selected schools in the Ohangwena region in Namibia. The study is an interpretive case study of two secondary schools in the above‐mentioned region in Namibia. The research utilized three quantitative data gathering techniques, namely semi‐structured interviews, observation and document analysis. The research participants were two principals, two teachers and two school board members from each research school. The main findings of this study revealed that the notion of participation of all stakeholders in education is seen as a fundamental aspect of the current leadership thinking. However, the respondents’ vision of leadership is limited and quite traditional in many ways. There is emphasis on the need to control, monitor, and delegate rather than team leadership. Furthermore, where consultation is mentioned it seems the respondents think of the passing down of information – a cascade model ‐ as consultation, a view that is narrow and inaccurate in terms of contemporary leadership theories. While there was an appreciation of the benefits derived from team leadership, challenges facing such leadership pervaded responses. These included lack of understanding of government policies such as ETSIP and NSPIs, resistance to change and implementation of policy. The study recommends that leadership and management programs and teacher leadership development programs be established in Namibia. Finally, the study recommends further research to include Learner Representative Council and Heads of Department. These stakeholders in education may provide new insights into the current school leadership thinking.
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- Date Issued: 2012
Research portfolio
- Authors: Mungongi, Fillemon
- Date: 2004
- Subjects: Education, Elementary -- Namibia Teaching -- Namibia Educational change -- Namibia English language -- Study and teaching (Elementary) -- Namibia Curriculum planning -- Namibia
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1937 , http://hdl.handle.net/10962/d1007716
- Description: 1. The contextual analysis and curriculum evaluation. This paper ... aims to investigate the Upper Primary Education Curriculum with specific emphasis on the subject syllabus for English Grades 5- 7. The paper shall attempt to look at the rationale, goals and aims as well as the learning content located in this subject curriculum. It will further investigate the sociohistoric and economic context in which this curriculum has been designed; the learners for whom the curriculum is designed and the learning environment in which the curriculum is presented. 2. The epistemological foundation of the reform process. This paper attempts to explore the theory of knowledge that underpins the practices of behaviourism and constructivism. 3. The literature review. The purpose of this literature review is to examine the effect of methodology in teaching English as a second language in primary schools. It is to find out the ways of teaching English that can produce good results. It is also to find the styles of teaching English as a second language that make some teachers less effective so that such teaching styles can be discouraged. When English was introduced as the medium of instruction in Namibian schools, primary school teachers were retrained and upgraded. 4. The research proposal. The aim of the proposed study is to explore a selection of learners' perceptions of ESL classroom teaching and learning activities. Through this it is hoped to cause greater illumination on the nature of learning and teaching English. 5. The empirical study (research paper). This interpretative case study hoped to find out from learners themselves about their perceptions of ESL classroom teaching and learning activities. A variety of research tools were used, including questionnaires, interviews, observations, interactive workshops and focus group discussions, all of which provided a rich source of data for interpretation. The research findings of this study clearly indicated that there is a mismatch between the teachers and learners' perceptions about the language skills and tasks encountered in the classrooms. From what was gained from the participants in this research, tentative suggestions are made.
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- Date Issued: 2004
Aspects of the biology of Caffrogobius Caffer (Günter) (Pisces : Teleostei : Gobiidae) in the Eastern Cape
- Authors: Butler, Graham Stuart
- Date: 1981
- Subjects: Osteichthyes -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5345 , http://hdl.handle.net/10962/d1006849
- Description: Several strategies used by the gobiid fish Caffrogobius caffer enabling it to colonise the harsh intertidal environment in the eastern Cape were studied. Q. caffer is opportunistic in its use of available food resources and feeds throughout the day with a slight tendency towards crepuscular peaks of feeding activity. The system of space utilisation used by C. caffer is so organised that all individuals of the population have access to patchily distributed food resources. Current velocities occurring over high tide limit the movements of Qo caffer and interpool movements occur only during the initial stages of a rising tide and in the final stages of an ebbing tide when the current velocities are below the tolerance limit of Q. caffer. The epifauna associated with the alga Ulva rigida, which forms an important constituent of the diet of the intermediate size classes of Q. caffer, was examined and it appears that this epifauna is an important source of food to Q. caffer. This report presents the results of the first detailed study of the biology of an intertidal fish in southern Africa.
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- Date Issued: 1981
Reproductive biology of important invasive plants in the Eastern Cape Province of South Africa
- Authors: Thorne, Cara-Jayne
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/3683 , vital:20535
- Description: Baker’s rule predicts species capable of uniparental reproduction are more likely to establish after long distance dispersal (or introduction in the case of invasive plants), thus the ability to undergo autonomous self-pollination should promote colonization. An investigation into the reproductive biology of eleven invasive species in the Eastern Cape Province of South Africa between 2012 and 2014 showed strong support for Baker’s law. Breeding system results showed evidence of self-compatibility in eight species, ten species were capable of autonomous self-pollination, and only three species showed evidence of varying levels of self-incompatibility. These results provide evdence that autonomous self-pollination occurs more frequently among invasive species, self-compatible species more frequently become invasive compared with self-incompatible species and that autogamous species should have a larger invasive range. Co-opting suitable local pollinators may be problematic for invasive plants, especially those with highly specialized pollination systems. The species investigated appear to be largely independent of pollinators, mostly setting seed in the absence of pollinators. Despite this, all eleven invasive plant species are regularly visited by a variety of generalist pollinators including Apis mellifera, Xylocopa bees and Allodapini species. Pollinators all carried substantial pollen loads, even managing to extract pollen from more specialized plants, such as the poricidal anthers of Solanum species, and frequently came into contact with both anthers and stigmas. Considering most of theses species are capable of autonomous self-pollination, their reliance on pollinators may be low. Even the most self-incompatible species, Passiflora caerulea, appears to have successfully co-opted local pollinators (honeybees and carpenter bees), ensuring successful pollination and seed set. The ability for cross-pollination by local pollinators allows for some degree of genetic variation within invasive plant populations, especially for self-incompatible species. Inadequate pollen deposition by unreliable or inefficient pollinators, or reduced resource availability, can result in pollen limitation. Invasive plant species may be especially susceptible, with three of the plant species investiagted showing possible pollen limitation at the level of seed set, while the remaining nine invasive plant species showed no evidence of pollen limitation in South Africa. The ability to utilize uniparental reproduction (as Baker’s law predicted), and co-opt local pollinators has allowed invasive plants in the Eastern Cape to successfully establish and persist after introduction. Hence, the inclusion of reproductive traits of plants should therefore be included in risk assessments for future plant invaders.
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- Date Issued: 2016
Investigating adaptation strategies to climate change by smallholder farmers : evidence from, Lesotho
- Authors: Morahanye, Mokhantso Lilian
- Date: 2017
- Subjects: Climatic changes -- South Africa Farms, Small -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/5807 , vital:29397
- Description: In Lesotho, agriculture is the dominant activity and involves crop and livestock production, range management and forestry activities. The current climatic variability in the country has caused decline in food production as result of increased dry spells, frequency of droughts and erratic rainfall. These climatic events are expected to have a significant impact on the livelihoods of the smallholder farmers. In combatting the harmful effects of climate change, smallholder farmers in Lesotho have employed various adaptation strategies based on their local knowledge and limited means. While these strategies may not be optimal they obviously constitute the basis for potentially effective improved technologies which can be developed and communicated through an efficient extension system, hence the need to precisely identify them and understand the factors that affect their choice. The main objective of this study was therefore, to identify the adaptation strategies and investigate the factors influencing smallholder farmers’ choice of those adaptation strategies. The study made use of multi-stage stratified sampling technique to select 160 respondents across four agro-ecological zones (lowlands, highlands, foothills and Senqu River Valley) in Leribe and Mohales’Hoek districts of Lesotho. Primary data for the study were collected using semi - structured questionnaire assisted with interview schedules administered on the respondents. Data collected were analysed using descriptive statistics and the multinomial logistics regression model. The results show that there are more males than females, majority of the respondents’ attained primary education, and older people dominate the smallholder farming system. The adaptation strategies used in MNL model were soil and water management, crop management and livestock management. The results further revealed that soil and water management strategies were the most adopted climate change strategies amongst smallholder farmers. It is understood that marital status, age and gender, income, land tenure, crop grown, extension services, and agro-ecological zones are the determinant factors influencing the choice of the adaptation strategies. This study concludes by recommending that smallholder farmers should be sensitised about climate change and both government and non-government organisations working on climate change related issues should direct their attention to rural communities to ensure effective response to climate change.
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- Date Issued: 2017
Physiochemical, fatty acids, lipid oxidation, sensory characteristics and consumer acceptance of warthog cabanossi produced with pork backfat and fat-tailed sheep backfat
- Authors: Mahachi, Leo Nyikadzino
- Date: 2017
- Subjects: Fatty acids Lipids -- Oxidation
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/6259 , vital:29530
- Description: The objective of this study was to determine the effect of different fat inclusion levels and fat types on the physical and chemical attributes, lipid oxidation, fatty acid composition and sensory characteristics of warthog cabanossi. To achieve this, three types of cabanossi with different pork backfat levels (10 percent, 20 percent and 30 percent) were produced for the first experiment. The results from the study showed that different inclusion levels of pork backfat had an influence (P ≤ 0.05) on the physicochemical and fatty acid composition of warthog cabanossi but did not influence lipid oxidation (P > 0.05). The highest (P ≤0.05) pH, weight and moisture decline was observed in the 10 percent pork backfat cabanossi compared to the 20 percent and 30 percent treatments. However, no differences (P > 0.05) in the water activity of the product were observed. As expected total fat was lower in the 10 percent fat treatment and increased concomitantly. Similarly, protein, ash and salt were higher in the 10 percent fat cabanossi and decreased concomitantly. Differences in the fatty acid composition were observed between treatments. Furthermore, backfat level affected the sensory attributes and consumer acceptance of the cabanossi. Ten percent backfat cabanossi was scored higher (P ≤0.05) for most sensory attributes. Consequently, it was observed that the consumer panel preferred and scored the 10 percent fat cabanossi higher with regards to appearance and taste. In the second experiment, two cabanossi treatments of different fat types (pork backfat and fat-tailed sheep backfat) were produced. The weight loss, moisture content, pH, water activity and salt content did not differ (P > 0.05) between the two cabanossi products. However, there were differences (P ≤0.05) in the protein, fat and ash contents; where protein and ash were higher in the pork backfat cabanossi whilst fat was higher in the sheep backfat cabanossi. Thiobarbituric reactive substances (TBARS) were similar (P > 0.05) between the two fat types cabanossi which could be explained by similar fatty acid profiles being reported for the two cabanossi although the n-6:n-3 ratio was higher (P ≤0.05) in sheep backfat cabanossi. Results from the descriptive sensory analysis showed two distinct products (P ≤0.01) where pork backfat cabanossi scored higher for most attributes. However, the lower scores for sheep backfat cabanossi were within an acceptable range. Sheep backfat cabanossi were also scored for unique attributes that were not detected in the pork backfat cabanossi. This study concluded that fat-tailed sheep backfat can be used to produce an unique cabanossi product of acceptable quality.
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- Date Issued: 2017