Regulation of Kaposi’s Sarcoma-Associated Herpesvirus Biology by Host Molecular Chaperones:
- Authors: Kirigin, Elisa , Ruck, Duncan Kyle , Jackson, Zoe , Murphy, James , McDonnell, Euan , Okpara, Michael O , Whitehouse, Adrian , Edkins, Adrienne L
- Date: 2020
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/165385 , vital:41239 , ISBN , https://0-doi.org.wam.seals.ac.za/10.1007/7515_2020_18
- Description: Kaposi’s sarcoma-associated herpesvirus (KSHV) is a gammaherpesvirus associated with development of the human diseases Kaposi’s sarcoma, Primary Effusion Lymphoma and Multicentric Castleman’s Disease. KSHV establishes a chronic latent infection in hosts, with periods of viral lytic replication, where both latent and lytic virus cycles contribute to malignancy, most often in the immunodeficient host.
- Full Text:
- Date Issued: 2020
Feasibility Study: Imagining A Cultural/Healing Centre for the Northern Areas of Nelson Mandela Bay: Oral accounts of people affected by the 1990 Uprising
- Date: 2016-10
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10948/41251 , vital:36422 , Bulk File 7
- Description: The Northern Areas History and Heritage Project consists of a variety workshops and materials examining the history of this part of Port Elizabeth to which people of colour had been removed in the 1970s. The materials include a book and DVD on the Northern Areas Uprising; six booklets entitled ‘Feasibility Study: Imagining a Cultural/ Healing Centre for the Northern Areas of Nelson Mandela Bay’ covering topics such as the Northern Areas Uprising, healing through memorialisation, architecture, non-profit organisations, archives and databases; 35 DVDs consisting of interviews with individuals, communities and focus groups, as well as a Winter School Project on Apartheid and the Group Areas Act. Also included are two maps relating to the area’s history.
- Full Text: false
- Date Issued: 2016-10
Audit, investigation, search, seizure and access to information
- Authors: Arendse, Jacqueline A , Clegg, David , Williams, Robert C
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/131245 , vital:36541 , https://store.lexisnexis.co.za/products/silke-on-tax-administration-skuZASKUPG1440
- Description: Chapter 5 of the Tax Administration Act, which supplements the various fiscal statutes, empowers SARS to call for information on taxpayers, conduct audits, investigations and in certain instances to search premises and seize goods and records. For this purpose, taxpayers are required to keep proper books and records (see § 8.2 and § 4). The purpose of a tax audit is to verify the accuracy and timing of an assessment, but more specifically to ensure accuracy and full disclosure in terms of the law. In the event that an audit reveals non-compliance, criminal and/or civil charges may be initiated by SARS (see § 8.5).
- Full Text: false
- Date Issued: 2016
Politics and discourse in South Africa:
- Authors: Hunt, Sally
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/139249 , vital:37719 , ISBN 9789027206565 , https://benjamins.com/catalog/dapsac.65
- Description: The discourses of the post-apartheid South Africa embody symbols of change and promises of new lessons in history. This is the first volume that brings together analyses of a variety of discourses produced in South Africa through which we follow the evolution of transitional processes in the country’s political institutions and in the opinions of its populace. The book offers to the reader a visit to the Parliament, a peek into the internet forums, analyses of the country's official papers and speeches, and the media accounts. Through all these discourses we see the burning questions – "Who Are We Now?" and "Who Do We Want To Be?" – being repetitively examined and identities cross-formed while the country deals with new, post-apartheid challenges, as well as successes.
- Full Text:
- Date Issued: 2015
“Mother of the Nation”: representations of womanhood in South African media
- Authors: Hunt, Sally
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/139229 , vital:37717 , ISBN 9789027206565 , https://benjamins.com/catalog/dapsac.65
- Description: The discourses of the post-apartheid South Africa embody symbols of change and promises of new lessons in history. This is the first volume that brings together analyses of a variety of discourses produced in South Africa through which we follow the evolution of transitional processes in the country’s political institutions and in the opinions of its populace. The book offers to the reader a visit to the Parliament, a peek into the internet forums, analyses of the country's official papers and speeches, and the media accounts. Through all these discourses we see the burning questions – "Who Are We Now?" and "Who Do We Want To Be?" – being repetitively examined and identities cross-formed while the country deals with new, post-apartheid challenges, as well as successes.
- Full Text:
- Date Issued: 2015
An overview of normative frameworks for the protection of development-induced IDPs in Kenya.
- Authors: Juma, Laurence
- Date: 2013
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/127112 , vital:35957 , https://doi.org/10.1163/17087384-12342016
- Description: Based on the assumption that development induced displacement brings new challenges that the existing protection frameworks may not be aptly suited to deal with, this article analyses how the existing laws have met this challenge and the prospects for further improvement. While its focus is on Kenya, it evaluates the normative quality of protection and standards offered by regional instruments against the existing, as well emerging, parameters for implementation at the domestic level. In this regard, the article examines the propriety of Kenya’s newly promulgated law on internal displacement in providing for protection for the development induced IDPs, the implementation programme that it establishes and its prospects for furthering the vision of the UN Guiding Principles on Internally Displaced and other regional instruments.
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- Date Issued: 2013
Evaluating the Wald entropy from two-derivative terms in quadratic actions
- Authors: Brustein, R , Gorbonos, D , Hadad, M , Medved, A J M
- Date: 2011
- Language: English
- Type: Article
- Identifier: vital:6816 , http://hdl.handle.net/10962/d1004326
- Description: We evaluate the Wald Noether charge entropy for a black hole in generalized theories of gravity. Expanding the Lagrangian to second order in gravitational perturbations, we show that contributions to the entropy density originate only from the coefficients of two-derivative terms. The same considerations are extended to include matter fields and to show that arbitrary powers of matter fields and their symmetrized covariant derivatives cannot contribute to the entropy density. We also explain how to use the linearized gravitational field equation rather than quadratic actions to obtain the same results. Several explicit examples are presented that allow us to clarify subtle points in the derivation and application of our method.
- Full Text:
- Date Issued: 2011
Late Quaternary environmental phases in the Eastern Cape and adjacent Plettenberg Bay-Knysna region and Little Karoo, South Africa
- Authors: Lewis, Colin A
- Date: 2011
- Language: English
- Type: Article
- Identifier: vital:6712 , http://hdl.handle.net/10962/d1006749
- Description: Four major climato-environmental phases have been identified in the Eastern Cape, Plettenberg Bay-Knysna region and Little Karoo between somewhat before ~ 40 000 cal. a BP and the present: the Birnam Interstadial from before 40 000 cal. a BP until ~ 24 000 cal. a BP; the Bottelnek Stadial (apparently equating with the Last Glacial Maximum) from ~24 000 cal. a BP until before ~ 18 350 cal. a BP; the Aliwal North (apparently equating with the Late Glacial) from before ~ 18 350 cal. a BP until ~ 11 000 cal. a BP; the Dinorben (apparently equating with the Holocene) from ~ 11 000 cal. a BP until the present. The evidence for, and the characteristics of, these phases is briefly described.
- Full Text:
- Date Issued: 2011
Introduction to Psychology II: PSY 122
- Authors: Van Heerden, R , Sandlana, N S
- Date: 2009-11
- Language: English
- Type: Examination paper
- Identifier: vital:18052 , http://hdl.handle.net/10353/d1010642
- Description: Introduction to Psychology II: PSY 122, degree examination November 2009.
- Full Text: false
- Date Issued: 2009-11
Nathaniel Merriman’s lecture: “Shakspeare, as Bearing on English History”
- Authors: Wright, Laurence
- Date: 2009
- Language: English
- Type: text , article
- Identifier: vital:7060 , http://hdl.handle.net/10962/d1007424 , http://hdl.handle.net/10520/EJC48132
- Description: preprint , “Shakspeare, as Bearing on English History” is the second of two lectures on Shakespeare given by Archdeacon Nathaniel Merriman in Grahamstown in 1857. The first was delivered in the Court House on the 2nd September 1857, and the second two months later, on Friday 6th November that same year, again in the Court House. The lecture was published in 1858. An article placing the lectures in their local context appeared in Shakespeare in Southern Africa 20 (2008): 25-37, accompanying an annotated edition of the first lecture, “On the Study of Shakspeare”. Readers desiring details of the editorial principles adopted in producing annotated editions of the two lectures are referred to the introductory material prefacing the first lecture.
- Full Text:
- Date Issued: 2009
Ecological thinking: Schopenhauer, J M Coetzee and who we are in the world
- Authors: Wright, Laurence
- Date: 2008
- Language: English
- Type: text , article
- Identifier: vital:7031 , http://hdl.handle.net/10962/d1007362 , https://doi.org/10.5848/CSP.0926.00001
- Description: preprint , For the ecological agenda to make substantive progress, we will have to see powerful people and social agencies turning away from the ecological insanity that threatens us all, and for this to happen, people need to embrace voluntary renunciation, on the understanding that this is not self-sacrifice, but a different and more satisfying way of being in the world. The paper offers some thought, provoked by reading J.M. Coetzee and Arthur Schopenhauer, about what would make this change possible, what might enable it; and secondly why it is implausible that any such ideal might actually come to pass.
- Full Text:
- Date Issued: 2008
Mussolini's moment: Roy Sargeant directs The Merchant of Venice at Maynardville, January, 2007
- Authors: Wright, Laurence
- Date: 2008
- Language: English
- Type: text , article
- Identifier: vital:7047 , http://hdl.handle.net/10962/d1007389 , http://hdl.handle.net/10520/EJC48107
- Description: preprint , What an inspired choice of play for this year’s Maynardville offering! With the national scene strewn with trials and rumours of trials, all of them vital to the quality of life citizens of this fair city beneath the beautiful mountain (‘Belmont’) may hope to enjoy in the future, Shakespeare’s cliff-hanger about the use and abuse of the law couldn’t be more apt.
- Full Text:
- Date Issued: 2008
Developing evidence-based practice: the role of case-based research
- Authors: Edwards, D J A , Dattilio, F M , Bromley, D B
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6243 , http://hdl.handle.net/10962/d1007856
- Description: How can practitioners engage in evidence-based practice when the evidence for effectiveness of psychological treatments comes from randomized controlled trials using patient populations different from those encountered in everyday settings and treatment manuals that seem oversimplified and inflexible? The authors argue that important evidence about best practice comes from case-based research, which builds knowledge in a clinically useful manner and complements what is achieved by multivariate research methods. A multidimensional model of the research process is provided that includes clinical practice and case-based research as significant contributors. The authors summarize the principles of case-based research and provide examples of recent technical advances. Finally, the authors suggest ways in which practitioners can apply the case-based approach in researching and publishing their own cases, perhaps in collaboration with university-based researchers.
- Full Text:
- Date Issued: 2004
The land is crying for justice: a discussion document on Christianity and environmental justice in South Africa
- Authors: Ecumenical Foundation of Southern Africa (EFSA)
- Date: 2002-06
- Subjects: Environmental justice -- Religious aspects -- Christianity , Social justice -- South Africa , Economics -- Religious aspects
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/68865 , vital:29333 , ISBN 187491723X
- Description: South Africa is a land of extraordinary beauty, ecological diversity and abundance. However, the land that God has entrusted to us is crying for justice. During the years of struggle against apartheid several ecumenical documents addressed the issues of the day. The Letter to the People of South Africa (1968), the Kairos Document (1985), the Evangelical Witness in South Africa (1986), the Road to Damascus (1989) and the Rustenburg Declaration (1990) may be mentioned in this regard. In the same ecumenical and prophetic spirit, this document seeks to address the escalating destruction of our environment that results in immense suffering for people, for other living species and for our land as a whole. In responding to this challenge Christians in South Africa may recognise, acknowledge and learn from the many voices and contributions on environmental concerns coming from all over the world — from churches and ecumenical movements, from the Earth Charter movement, from other religious traditions and from environmental organisations. The World Summit on Sustainable Development (WSSD) - 26 August to 4 September 2002, Johannesburg - also challenges the churches in South Africa to respond to these concerns. , 1st ed , Ecumenical Foundation of Southern Africa (EFSA)
- Full Text:
- Date Issued: 2002-06
Nurses' experience of contesting discourses in HIV/AIDS activities in the primary health care setting
- Authors: Tutani, Lumka
- Date: 2001
- Subjects: Primary health care , AIDS (Disease) -- Nursing , AIDS (Disease) -- Patients -- Counseling of
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3074 , http://hdl.handle.net/10962/d1002583 , Primary health care , AIDS (Disease) -- Nursing , AIDS (Disease) -- Patients -- Counseling of
- Description: This paper explores the experience of nurses who work both as Primary Health Care Providers and counsellors trained in the narrative model of counselling in primary health care settings. Five focus groups were conducted in both Xhosa and English. Discourse analysis was used as a method of analysing the data. Training nurses in the narrative counselling model introduced an alternative discourse, which was experienced as contradicting their usual way of working. Two dominant discourses were the “not knowing” approach, assumed by the narrative model of counselling, and the “knowing” stance, assumed by health education. The institutionalised construction of counselling by doctors and matrons, and their power versus the power of the nurse counsellors was also cited as sources of conflict. Despite the tensions, narrative model of counselling seems to be offering new positions, which may benefit people living with HIV and improve HIV/AIDS activities in the Primary Health Care (PHC) context.
- Full Text:
- Date Issued: 2001
Teenage motherhood and the regulation of mothering in the scientific literature: the South African example
- Authors: Macleod, Catriona I
- Date: 2001
- Language: English
- Type: Article
- Identifier: vital:6256 , http://hdl.handle.net/10962/d1007874
- Description: The mainstream literature on teenage pregnancy highlights teenagers' inadequate mothering as an area of disquiet. `Revisionists', such as feminist critics, point out that a confluence of negative social factors is implicated in teenagers' mothering abilities. Whether arguing that teenagers make bad mothers or defending them against this, the literature relies on the `invention of "good" mothering'. In this article I highlight the taken-for-granted assumptions concerning mothering (mothering as an essentialized dyad; mothering as a skill; motherhood as a pathway to adulthood; fathering as the absent trace) appearing in the scientific literature on teenage pregnancy in South Africa. I indicate how these assumptions are implicated in the regulation of mothering through the positioning of the teenage mother as the pathologized other, the splitting of the public from the private, domestic space of mothering, and the legitimation of the professionalization of mothering. I explore the gendered implications of the representations of mothering in this literature.
- Full Text:
- Date Issued: 2001
Discussion document prepared for COSATU Gender Conference
- Authors: NALEDI
- Date: 2000
- Subjects: NALEDI
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/151190 , vital:39037
- Description: Despite the massive contribution women make around the world, they still fall into the category of the poorest and the most oppressed. Women have borne the brunt of the social costs of the changes in the world economy such as globalisation, increased international competition, structural adjustment and the deregulation of labour legislation. Massive technological advances have done little to benefit women around the world. In fact, in many instances it has actually increased their hardships. Multinational companies search the globe for areas that offer cheap labour and poor working conditions. Globally, women make up the bulk of the army of so-called “flexible”, cheap workers sought after by employers anxious to increase their profits. It is women who are mostly to be found in sweatshops and who are least likely to be organised. In South Africa, there is already a significant trend of homeworking in the clothing sector and casualisation in the retail and other sectors. And when they are organised into unions, women struggle to be recognised as leaders in those movements.
- Full Text:
- Date Issued: 2000
Globalising poverty: The gender dimension to Job Losses, Casualisation and Poverty
- Authors: NALEDI
- Date: June 2000
- Subjects: NALEDI
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/167919 , vital:41522
- Description: Despite the massive contribution women make around the world, they still fall into the category of the poorest and the most oppressed. Women have borne the brunt of the social costs of the changes in the world economy such as globalisation, increased international competition, structural adjustment and the deregulation of labour legislation. Massive technological advances have done little to benefit women around the world. In fact, in many instances it has actually increased their hardships. Multinational companies search the globe for areas that offer cheap labour and poor working conditions. Globally, women make up the bulk of the army of so-called “flexible”, cheap workers sought after by employers anxious to increase their profits. It is women who are mostly to be found in sweatshops and who are least likely to be organised. In South Africa, there is already a significant trend of homeworking in the clothing sector and casuahsation in the retail and other sectors. And when they are organised into unions, women struggle to be recognised as leaders in those movements. With massive retrenchments in the South African economy, more and more women are being pushed out of the labour market. Women’s unemployment rate is higher than men’s world-wide. The spate of retrenchments and job losses in the last few years have been described as a “job loss bloodbath”. According to recent statistics 1 million jobs have been lost since 1994 - what does this say about GEAR’S employment record? The mining and construction industries have suffered the largest job losses in the South African economy. While the workforce in these industries is predominantly male, and mostly migrant labour, the impact on women and families in rural areas is high, given the extreme rates of unemployment and poverty and their reliance on remittances. The clothing, textile, leather and footwear industry, which is female-dominated, has also been hard hit by retrenchments - approximately 76 000 jobs have been lost since 1995.
- Full Text:
- Date Issued: June 2000
Petrogenesis of late Archaean flood-type basic lavas from the Klipriviersberg Group, Ventersdorp Supergroup, South Africa
- Authors: Marsh, Julian S , Bowen, M P , Rogers, N W , Bowen, T B
- Date: 1992
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145829 , vital:38470 , https://doi.org/10.1093/petrology/33.4.817
- Description: The Klipriviersberg Group is a small continental flood-type tholeiitic suite forming the basal unit of the Ventersdorp Supergroup, an undeformed late-Archaean supracrustal sequence covering 200000 km2 in the SW part of the Kaapvaal Craton. From the base up, the Klipriviersberg Group consists of the Westonaria, Alberton, Orkney, Jeannette, Loraine, and Edenville formations, with a maximum combined thickness of 1–8 km. Samples were obtained from several borehole cores in the Klerksdorp goldfield close to the type area of the Klipriviersberg Group.
- Full Text: false
- Date Issued: 1992
Changing attitudes of Black South Africans toward the United States of America
- Authors: Hirschmann, David
- Date: 1987
- Subjects: Public opinion -- South Africa Black people -- South Africa -- Attitudes United States -- Relations -- South Africa South Africa -- Relations -- United States United States -- Foreign public opinion, South African
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/1888 , vital:20236 , ISBN 0868101494
- Description: There is a tendency to term a major civil uprising a "revolution" only after it has succeeded to come close to success. While the final outcome of the present strife in South Africa remains uncertain, its dimensions amount to a revolution: in terms of breadth and depth of hostility, the determination to demonstrate the express that hostility, the period of sustained violence and disruption, the suffering involved and the acceptance of that suffering as essential to change, and the uncompromising and the increasingly fundamental objectives of the movement. The conflict has, of course, been there for centuries. The movement for change has been building up for most of this century. It has never been allowed to gain effective momentum. The present situation is different: it represents a broad, serious and sustained threat to the continuation of white rule. In accordance with the simple model set out above, the white rulers are pro-Western (President Botha has made much of this), capitalist (and of this too) and receive effective backing from domestic and international corporations, and from major Western Governments, such as the United Kingdom, the United States, West Germany and Japan. There are, however, certain specifics of the South African situation, and of its relationship with the United States, which must be kept in mind. For a start, the United States is not the ex-colonial power (as in the Philippines), nor is it the historical regional power (as in Latin America) nor the dominant proximate power (as in Nicaragua). Second, race is so important an element in this conflict, that notions of class exploitation and imperialism, as analytically valid as they may be, may have a more difficult time in taking hold of the minds of black South Africans. Third, and related to race, the United States experience with the civil rights movement may be seen by some blacks as having been successful, and therefore indicative of a political system worthy of respect. Fourth, the diplomatic activities of the United States under leaders like Kennedy and Carter may have left a residue of respect for United States intentions, and a readiness to distinguish Reagan's Constructive Engagement from an entity called "the United States Government", or from "the United States" as a whole. People may also distinguish between more or less progressive corporations, and between those companies and the United States Government. Further, for decades United States entertainment and mass media have strengthened bonds of music, humour, fashions and fun: there is a long-standing mass cultural connection between black South Africans and the United States which may influence evolving attitudes. There is no comparable connection with Eastern countries. Through strict censorship and control of education, black South Africans will have been denied the material on which to build a full understanding of the East. A number of leading blacks have trained or been on extended visits to Western countries. A number of them are religious leaders, such as Boesak and Tutu, who, while angry with the West, are not pro-communist in any form. The principal liberation organization, the African National Congress (ANC), emphasises a rather open-ended and undefined socialism, contains divergent ideological threads, and continues to court Western support. Furthermore, inside the country, radicalism may be more concerned with "black" radicalism than with "class" radicalism. It is also uncertain what lessons South African blacks have learned from the twenty-five years of domestic and foreign policy experience of independent Africa, nor how they assess the Mozambican, Angolan and Zimbabwean revolutionary and post-revolutionary programe, nor do we know how all of this effects the vision black South Africans hold of post-apartheid South Africa's future and of its place in the world. The purpose of the research was to begin to try to find answers to some of these questions, and in particular to investigate attitudes of black South African towards the United States of America; more particularly to observe if changes in attitude were taking place as the current prolonged period of crisis takes its course. , Digitised by Rhodes University Library on behalf of the Institute of Social and Economic Research (ISER)
- Full Text:
- Date Issued: 1987