An Evaluation of the Role of an Intermediate Care Facility in the Continuum of Care in Western Cape, South Africa
- Authors: Sikhumbuzo A. Mabunda , Leslie London , David Pienaar
- Date: 2018
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4888 , vital:44299
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A mathematical model and application for fire risk management in commercial complexes in South Africa
- Authors: Felix Ishola , Victor Oladokun , Omolayo Petinrin , Obafemi Olatunji , Stephen Akinlabi
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4176 , vital:44035
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Risk factors and outcomes of acute kidney injury in South African critically ill adults: a prospective cohort study
- Authors: Ryan E. Aylward , Elizabeth van der Merwe , Sisa Pazi , Minette van Niekerk , Jason Ensor , Debbie Baker , Robert J. Freercks
- Date: 2019
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4465 , vital:44122
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JOURNAL ARTICLE B.pdf
- Authors: Grace Emily Okuthe
- Subjects: sex inversion, danio rerio, gonad, mitotic, development
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/2333 , vital:41323
- Description: published papers by Prof Grace Emily Okuthe
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Clinical and demographic profile of catatonic patients who received electroconvulsive therapy in a South African setting
- Authors: Kavendren Odayar , Ingrid Elof , Willem Esterhuysen
- Date: 2018
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4719 , vital:44168
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Morphology, histology and histochemistry of the digestive tract of the Banded tilapia, Tilapia sparrmanii (Perciformes: Cichlidae)
- Authors: Grace E. Okuthe , Bongile Bhomela
- Date: December 23, 2020
- Subjects: Fish, gastrointestinal tract, histo-architecture
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/2425 , vital:41881
- Description: ABSTRACT. This study described anatomical, histological and histochemical features of the mucosal layer of the digestive tract of Tilapia sparrmanii Smith, 1840, an omnivorous freshwater fish endemic to Southern Africa. This species exhibited a short thick oesophagus with long deep longitudinal folds (466.68 ± 16.91 µm), and a thick (173.50 ± 10.92 µm) muscular layer that allow the passage of large food items. The mucosa was lined with stratified secretory epithelium rich in goblet cells that secreted neutral and acid mucins. The stomach was a sac-like structure with simple tubular glands surrounded by connective tissue. The mucosa was lined with simple columnar epithelium and the lamina propria exhibited a well-developed layer of gastric glands that occupied the entire length of the cardio-fundic region. The stomach mucosa consisted of epithelial cells with intense neutral mucin secretion which protects against gastric juice. Neck cells of gastric glands synthesized neutral and acid mucins. The intestine was highly coiled and presented a complex pattern of transversal folds internally (villi). Villi length decreased progressively from the anterior to the posterior intestine (p < 0.0001). Tunica muscularis of the mid-intestine had the thinnest thickness among all parts of the intestine (p < 0.0001). Goblet cells whose numbers increased towards the rectum secreted both acid and neutral mucins. The results indicate structural similarities of T. sparrmanii GIT with other tilapia species and will be useful for understanding the physiology of the digestive systems as well as functional components of the GIT.
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Change in renal function post-nephrectomy for renal cell carcinoma in patients with and without hypertension and/or diabetes
- Authors: John, J , Henry, M , Ringoir, A , Pinto, G , Kesner, K , Lazarus, J , Sinha, S
- Date: 2020
- Subjects: RCC, Nephrectomy, eGFR, CKD
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/6368 , vital:45380
- Description: BACKGROUND: The standard of care for surgically resectable disease renal cell carcinoma (RCC) is a nephrectomy. Post nephrectomy, these patients are at risk for the development of new onset chronic kidney disease or the progression of pre-existing chronic kidney disease. We aimed to report the changes in renal function in patients who had a nephrectomy for RCC METHODS: This retrospective, descriptive, cross-sectional study identified 137 patients who had a nephrectomy for RCC from 1 January 2009 to 31 December 2017. The pre-nephrectomy and post-nephrectomy estimated glomerular filtration rate (eGFR) and the histological subtype of RCC on histopathological analysis of the resected specimen were recorded from the National Health Laboratory Services online results platform. All analyses were conducted using SPSS (Version 25) and the significance level was set at p < 0.05 RESULTS: After a mean follow-up period of 26.5 ± 22 months (median = 19 months), the patients' eGFR dropped by a mean of 4.82 ± 8.67 ml/min/1.73 m2 (95% CI 3.23-6.41) post-nephrectomy. The mean eGFR fall in patients' who had hypertension and/or diabetes (n = 63) was significantly larger compared to patients who had neither of these comorbidities (n = 54; p < .001; mean = 7.30 ± 8.40 ml/min/1.73 m2 (95% CI 5.19-9.42) and 1.93 ± 8.14 ml/min/1.73 m2 (95% CI 0.30-4.15) respectively CONCLUSIONS: The decline in renal function in patients with hypertension and/or diabetes mellitus is more pronounced than in patients with neither of these comorbidities. In these high-risk patients, measures must be taken to prevent the development and limit the progression of chronic kidney disease
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Factors associated with glycemic control among South African adult residents of Mkhondo municipality living with diabetes mellitus
- Authors: Charity Masilela , Oladele Vincent Adeniy , Brendon Pearce , Joven Jebio Ongole , Mongi Benjeddou
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4642 , vital:44148
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Rapid testing for respiratory syncytial virus in a resource-limited paediatric intensive care setting
- Authors: Howard Newman , Sikhumbuzo Mabunda , Donald Tshabalala , Nokwazi Nkosi , Candice Care
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4249 , vital:44052
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Twenty-four-hour oesophageal pH studies in rural Eastern Cape Province, South Africa
- Authors: E J Ndebia , A M Sammon
- Date: 2018
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4751 , vital:44186
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On the Derivation of Nonclassical Symmetries of the Black–Scholes Equation via an Equivalence Transformation
- Authors: Winter Sinkala
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4335 , vital:44106
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Ageing, exposure to pollution, and interactions between climate change and local seasons as oxidant conditions predicting incident hematologic malignancy at KINSHASA University clinics, Democratic Republic of CONGO (DRC)
- Authors: Mireille Solange Nganga Nkanga , Benjamin Longo-Mbenza , Oladele Vincent Adeniyi , Jacques Bikaula Ngwidiwo , Antoine Lufimbo Katawandja , Paul Roger Beia Kazadi , Alain Nganga Nzonzila
- Date: 2017
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/3988 , vital:43980
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African Oral Literature and the Humanities: Challenges and Prospects
- Authors: Enongene Mirabeau Sone
- Date: 2018
- Subjects: folklore; oral literature; humanities; Africa; education; place; education; universities; curriculum
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/2664 , vital:42311
- Description: This paper examines the origin, evolution and emergence of folklore (oral literature) as an academic discipline in Africa and its place in the humanities. It draws attention to the richness of indigenous knowledge contained in oral literature and demonstrates how the ethical and moral gap in the existing educational system can be filled by the moral precepts embedded in oral literature. The paper argues that African oral literature has not received the attention it deserves among other disciplines of the humanities in institutions of higher learning in Africa. It concludes that any discussion on African literature will be incomplete, and indeed irrelevant, if it does not equally give adequate attention to the oral literature of the African people. As a result, a new curriculum and pedagogy must be designed to give pride of place to folklore and oral literature as the best repository of our cultural norms and values especially in African tertiary institutions.
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Predictors of institutional delivery service utilization among women of reproductive age in Senegal: a population-based study
- Authors: Betregiorgis Zegeye , Bright Opoku Ahinkorah , Dina Idriss-Wheelr , Olanrewaju Oladimeji , Comfort Z. Olorunsaiye , Sanni Yaya
- Date: 2021
- Subjects: Institutional delivery, Women, Reproductive age, Senegal, Maternal health, Global health, Sub-Saharan Africa
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4496 , vital:44126
- Description: Background: In Senegal, sub-Saharan Africa, many women continue to die from pregnancy and childbirth complications. Even though health facility delivery is a key intervention to reducing maternal death, utilization is low. There is a dearth of evidence on determinants of health facility delivery in Senegal. Therefore, this study investigated the predictors of health facility-based delivery utilization in Senegal. Methods: Data from the 2017 Senegal Continuous Survey were extracted for this study, and approximately 11,487 ever-married women aged 15–49 years participated. Chi-square test was used to select significant variables and multivariable logistic regression analysis was performed to identify statistically significant predictors at a 95% confidence interval with a 0.05 p-value using Stata version 14 software. Results: Facility-based delivery utilization was 77.7% and the main predictors were maternal educational status (primary school Adjusted Odds Ratio [aOR] = 1.44, 95% CI; 1.14–1.83; secondary school aOR = 1.62, 95% CI; 1.17– 2.25), husband’s educational status (primary school aOR = 1.65, 95% CI; 1.24–2.20, secondary school aOR = 2.17, 95% CI; 1.52–3.10), maternal occupation (agricultural-self-employed aOR = 0.77, 95% CI; 0.62–0.96), ethnicity (Poular aOR = 0.74, 95% CI; 0.56–0.97), place of residence (rural aOR = 0.57, 95% CI; 0.43, 0.74), media exposure (yes aOR = 1.26, 95% CI; 1.02–1.57), economic status (richest aOR = 5.27, 95% CI; 2.85–9.73), parity (seven and above aOR =0.46, 95% CI; 0.34–0.62), wife beating attitude (refuse aOR =1.23, 95% CI; 1.05–1.44) and skilled antenatal care (ANC) (yes aOR = 4.34, 95% CI; 3.10–6.08). Conclusion: Uptake of health facility delivery services was seen among women who were educated, exposed to media, wealthy, against wife-beating, attended ANC by skilled attendants and had educated husbands. On the other hand, women from ethnic groups like Poular, those working in agricultural activities, living in rural setting, and those who had more delivery history were less likely to deliver at a health facility. Therefore, there is the need to empower women by encouraging them to use skilled ANC services in order for them to gain the requisite knowledge they need to enhance their utilization of health facility delivery, whiles at the same time, removing socio-economic barriers to access to health facility delivery that occur from low education, poverty and rural dwelling.
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Comprehensive data on the mechanical properties and biodegradation profile of polylactide composites developed for hard tissue repairs
- Authors: Abraham K. Aworinde , Samson O. Adeosun , Festus A. Oyawale , Eyere Emagbetere , Felix A. Ishola , Obafemi Olatunji , Stephen A. Akinlab , Sunday O. Oyedepo , Oluseyi O. Ajayi , Esther T. Akinlabi
- Date: 2020
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4152 , vital:44032
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The association between HIV tri-therapy with the development of Type-2 Diabetes Mellitus in a rural South African District: A case-control study
- Authors: Nokwanda E. Bam , Teke Apalata , Sikhumbuzo A. Mabunda , Jafta Ntsaba , Sibusiso C. Nomatshila , Wezile Chitha
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4667 , vital:44155
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Assessment of minor psychiatric morbidity, stressors, and barriers of seeking help among medical students at the University of Khartoum, Khartoum, Sudan
- Authors: Muwada Bashir Awad Bashir , Sara Omer Abdelazim Mohamed , Claude Ngwayu Nkfusai , Fala Bede , Olanrewaju Oladimeji , Joyce Mahlako Tsoka-Gwegweni , Samuel Nambile Cumber
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4192 , vital:44037
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Umbilical cord interleukin-6 predicts outcome in very low birthweight infants in a high HIV-burden setting: a prospective cohort study
- Authors: Mackay , Cheryl Anne , Smit, James Stephanus , Khan, Farhaad , Dessai, Fazana , Connolly, Catherine , Masekela, Refiloe
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/6376 , vital:45384
- Description: Objectives South Africa has a double burden of high neonatal mortality and maternal HIV prevalence. Common to both is a proinflammatory in utero and perinatal milieu. The aim of this study was to determine cytokine profiles in HIV exposed (HE) and HIV unexposed (HU) very low birthweight (VLBW) infants and to determine whether these were associated with predischarge outcomes. Design Single-centre, prospective cohort study conducted from 1 June 2017 to 31 January 2019. Patients Inborn infants with birth weight of <1500 g were enrolled and cord blood was collected for interleukin (IL)-6 and tumour necrosis factor alpha (TNF-α) assays. Participants provided informed consent and ethics approval was obtained. Outcome measures The primary outcome was umbilical cord cytokine levels according to maternal HIV status. Secondary outcomes included death and/or serious neonatal infection, necrotising enterocolitis, intraventricular haemorrhage, periventricular leucomalacia, chronic lung disease and haemodynamically significant patent ductus arteriosus before discharge. Results A total of 279 cases were included with 269 cytokine assays performed on 122 HEs and 147 HUs. Median IL-6 levels were 53.0 pg/mL in HEs and 21.0 pg/ mL in HUs (p=0.07). Median TNF-α levels were 7.2 pg/ mL in HEs and 6.5 pg/mL in HUs (p=0.6). There was significantly more late-onset sepsis in the HE group compared with the HU group (41.2% vs 27.9%) (p=0.03). IL-6 levels were significantly higher for those with any adverse outcome (p=0.006) and death and/or any adverse outcome (p=0.0001). TNF-α levels did not differ according to predischarge outcomes. Conclusion There is no significant difference in IL-6 and TNF-α levels in cord blood of HE compared with HU VLBWs. However, IL-6 levels are significantly higher in VLBWs with adverse predischarge outcomes, and VLBW HEs are at increased risk of adverse predischarge outcomes compared with HUs, particularly late-onset sepsis.
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The Role of T Helper 17 (Th17) and Regulatory T Cells (Treg) in the Pathogenesis of Vulvovaginal Candidiasis among HIV-Infected Women
- Authors: Teke Apalata , Benjamin Longo-Mbenza
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4363 , vital:44109
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Implementing a total reward strategy in selected South African municipal organisations
- Authors: Patrick W. Bwowe , Newlin Marongwe
- Date: 2018
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4233 , vital:44048
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