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The effects of point of substitution on the formation of manganese phthalocyanine-based molecular materials

  • Authors: Akinbulu, Isaac Adebayo , Khene, Samson , Nyokong, Tebello
  • Date: 2010
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/249103 , vital:51778 , xlink:href="https://doi.org/10.1016/j.tsf.2010.08.145"
  • Description: Molecular films of manganese phthalocyanine (MnPc) complexes, tetra-substituted with 2-diethylaminoethanethio at the peripheral (Mn(OAc)-β-TDEAETPc, 1) and non-peripheral (Mn(OAc)-α-TDEAETPc, 2) positions were formed on glassy carbon electrode by electropolymerization and electrodeposition respectively. Atomic force microscopy images confirmed the presence of the films and revealed significant morphological differences. The films exhibited an electrocatalytic activity towards the oxidation of the insecticide, bendiocarb. Hydrodynamic technique, using rotating disc electrode voltammetry, was used to investigate the kinetics of electro-oxidation of the insecticide. Morphological differences of the films significantly influenced kinetic parameters. Values of Tafel slopes, obtained from Tafel plots, suggested that catalysis of bendiocarb occurred via outer sphere mechanism.
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  • Date Issued: 2010

The effects of point of substitution on the electrochemical behavior of new manganese phthalocyanines, tetra-substituted with diethylaminoethanethiol

  • Authors: Akinbulu, Isaac Adebayo , Nyokong, Tebello
  • Date: 2010
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/249137 , vital:51781 , xlink:href="https://doi.org/10.1016/j.ica.2010.06.003"
  • Description: The syntheses and comparative studies of the spectral, voltammetry and spectroelectrochemical properties of new manganese phthalocyanine complexes, tetra-substituted with diethylaminoethanethio at the peripheral (complex 3a) and non-peripheral positions (complex 3b) are reported. Solution electrochemistry of complex 3a showed quasi-reversible metal-based (MnIIIPc−2/MnIIPc−2, E1/2 = −0.07 V vs. Ag|AgCl) and ring-based (MnIIPc−2/MnIIPc−3, E1/2 = −0.78 V vs. Ag|AgCl) reductions, but no ring-based oxidation. However, complex 3b showed weak irreversible ring-oxidation signal (Ep = +0.86 vs. Ag|AgCl). Reversible metal-based (MnIIIPc−2/MnIIPc−2, E1/2 = −0.04 V vs. Ag|AgCl) and ring-based (MnIIPc−2/MnIIPc−3, E1/2 = −0.68 V vs. Ag|AgCl) reductions were also observed for complex 3b. Spectroelectrochemistry was used to confirm these processes. Reduction process involving the metal (MnIIIPc−2/MnIIPc−2) was associated with the formation of manganese μ-oxo complex in complex 3a.
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  • Date Issued: 2010

Formation, surface characterization, and electrocatalytic application of self-assembled monolayer films of tetra-substituted manganese, iron, and cobalt benzylthio phthalocyanine complexes

  • Authors: Akinbulu, Isaac Adebayo , Ozoemena, Kenneth Iyke , Nyokong, Tebello
  • Date: 2011
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/247163 , vital:51552 , xlink:href="https://doi.org/10.1007/s10008-010-1243-1"
  • Description: Molecular thin films of manganese (SAM-2), iron (SAM-3), and cobalt (SAM-4) phthalocyanine complexes, non-peripherally tetra-substituted with benzylmercapto, were formed on polycrystalline gold disc electrode by self-assembly technique. Surface characteristics of the films were interrogated by cyclic voltammetry. Significant passivation of voltammetry processes associated with bare gold surface (gold oxidation and underpotential deposition of copper) confirmed formation of the films. Electrocatalytic property of the films was evidenced from better voltammetry responses (less positive oxidation potential and better current signal) of the insecticide, carbofuran, on these films, relative to that on bare gold electrode. In terms of less positive oxidation potential, the FePc derivative (3) gave the best response, while the best current signal was observed on SAM-2-modified gold electrode. The average heterogeneous rate constant, k, for the oxidation of carbofuran was 3.6 × 10−2 cm s−1 on the SAM film with the best current signal (SAM-2).
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  • Date Issued: 2011

Water restriction and vitamin c supplementation on Xhosa goats during summer: Effect on growth performance, blood biochemical profile, nutrient balance, carcass characteristics and meat quality

  • Authors: Akinmoladun, Oluwakamisi Festus https://orcid.org/0000-0001-6462-374X
  • Date: 2020-08
  • Subjects: Goats -- Nutrition , Goats -- Feeding and feeds
  • Language: English
  • Type: Doctoral theses , text
  • Identifier: http://hdl.handle.net/10353/22710 , vital:52664
  • Description: This study aimed to evaluate the effect of single and extra vitamin C (VC) supplementation on water-stressed Xhosa goats during the summer by evaluating their growth performance, blood biochemical profile, nutrient balance, carcass characteristics and meat qualities. The objectives were to assess the effect of water restriction and vitamin C supplementation by evaluating: firstly, growth performance, heat tolerance responses, and blood metabolites; secondly, intake, nutrient digestibility, nitrogen and mineral balance; thirdly, stress indices, carcass characteristics and meat qualities parameters and lastly, fatty acid profile, oxidative stability of lipids and sensory attributes were evaluated. To achieve these objectives, forty-two (42) goats were divided equally into seven treatments (75-day trial); without water restriction (W0, control); water restriction of 70percent of ad libitum water intake WI (W70); water restriction of 50percent ad libitum WI (W50); water restriction of 70percent of ad libitum WI plus 3g VC daily (W70+); water restriction 50percent of ad libitum WI plus 3g VC daily (W50+); water restriction of 70percent of ad libitumWI plus 3g VC and extra 5gVC given every eight-day (70++); water restriction of 50percent of ad libitum WI plus 3g VC and extra 5gVC given every eight-day (W50++). In the first objective, growth performance parameters, body condition scores, rectal temperature, respiratory rate, heat tolerance response parameters and blood metabolites were measured.Weight loss due to water restriction was reduced by VC supplementation in treated groups. The attenuation effect of VC was significant (P<0.05) in responses to respiratory rate (RR), Na+, K+, Mg2+, Cl-, Ca2+ and urea. Supplementation of VC (either single or multiple) did not (P>0.05) improve the effect of water restriction on body condition scores (BCs), FAMACHA©, glucose, globulin, alanine aminotransferase (ALT) and high-density lipoprotein (HDL). In the second objective, intake, nutrient digestibility, nitrogen and mineral balance were evaluated. The reduced nutrient intake was similar (P>0.05) irrespective of water restrictions and VC supplementations. Water-restriction levels did not affect nutrient intake/metabolic weight. Retained nitrogen increased with water-restriction levels but not influenced by VC. NH3-N decreased with the levels of water restriction while the pH was similar across the water restricted groups. Supplementation of VC had no effect (P>0.05) on apparent digestibility and digestible nutrients induced by water restriction levels. The amount of Ca, K, Mg retained increased (P<0.05) with water-restriction levels. In the third objective, stress indices, carcass characteristics and meat quality parameters were evaluated. The level of plasma cortisol concentration due to water stress was lessened (P<0.05) by VC. Follicle stimulating hormone (FSH), Luteinizing hormone (LH) and insulin were not affected (P>0.05) by levels of water restriction. The hot and carcass weights were lower (P<0.05) in W70+ and W50+ compared to W70 and W50 respectively. Vitamin C treated goats had higher redness (a*) compared to W70, W50 and W0. The shear force and cooking loss increased (P<0.05) with water restriction levels, while thaw loss, pH45min and pH24h were not affected by water restriction levels. In the final objective, the treatments did not affect (P>0.05) the oxidative stability of lipids (TBARS). The moisture and fat content in the water restricted groups were lower (P<0.05) than W0. The consumer meat sensory appearance decreased (P<0.05) with levels of water restrictions. Regardless of VC concentration and supplementation, vaccenic, and docosahexaenoic acid increased (P<0.05) while linolenic acid decreased as the water restriction levels increased. Nonetheless, treatment did not affect (P>0.05) the saturated and unsaturated fatty acids. These studies showed that suboptimal water intake negatively affects the growth performance and nutrient intake of Xhosa goats. However, the reduction in body weight loss and decreased plasma cortisol (chief stress hormone) concentration following vitamin C supplementation (especially at a daily single dose [3g/d]) may well reduce the effect of water stress in goats. , Thesis (PhD) -- Faculty of Science and Agriculture, 2020
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  • Date Issued: 2020-08

Agricultural entrepreneurship development as strategy for economic empowerment: The case of small-scale farmers in Eastern Cape Province of South Africa

  • Authors: Akinwale, Olusola Mokayode
  • Date: 2020-11
  • Subjects: Sustainable development -- South Africa -- Eastern Cape , South Africa -- Economic conditions
  • Language: English
  • Type: Doctoral theses , text
  • Identifier: http://hdl.handle.net/10353/20241 , vital:45637
  • Description: This study emanated from the struggle for economic empowerment among small-scale farmers in South African. The study advocates for the establishment of a viable environment where agricultural entrepreneurship can thrive. While the South African Nation Development Plan (NDP) proposed to create one million jobs through agricultural sector by 2030, the majority of small-scale farmers in South Africa are struggling to grow beyond the level of subsistence farming, and the youths appear not to be interested in the farming. It is therefore become necessary to conduct this current study that is exploratory in nature; it explored several factors and barriers to agricultural entrepreneurship development, as well as factors that can contribute to the development of prosperous and sustainable agricultural entrepreneurship among small-scale farmers in South African. The study was conducted in two district municipalities of Eastern Cape Province of South Africa – OR Tambo and Chris Hani. Both quantitative and qualitative research methods were used to make findings. Findings from the study shows that economic empowerment can be achieved through agricultural entrepreneurship development by giving adequate attention to specific factors like individuals’ attitude, production skills, access to market and marketing skills, management skills. Empirically, basic components like personal interests, adequate training and background, efficient extension service, famers’ network and communication, specific goal-oriented, understanding market, farmers’ collaboration, and access to sufficient funding are few of the factors that will make the small-scale farmers grow to the level of commercial farming. The study concluded that prerequisite to developing a sustainable agricultural entrepreneurship climate among small-scale farmers in South African is the combination of basic components aforementioned. Suggestions were made for strong collaboration between government and private sectors to provide development assistance for small-scale farmers as they struggles to develop their small-scale farming to sustainable entrepreneurship level. , Thesis (DPhil) -- Faculty of Management and Commerce, 2020
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  • Date Issued: 2020-11

Photophysical and photochemical parameters of octakis (benzylthio) phthalocyaninato zinc, aluminium and tin

  • Authors: Akpe, Victor , Brismar, Hjalmar , Nyokong, Tebello , Osadebe, Patience Ogoamak
  • Date: 2010
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/248472 , vital:51689 , xlink:href="https://doi.org/10.1016/j.molstruc.2010.08.033"
  • Description: This paper addresses the synthesis of octa-substituted benzylthio metallophthalocyanines (OBTMPcs) that contain the central metal ions of Zn2+, Al3+ and Sn4+. The ground state absorption of ZnPc(SR)8 (OBTZnPc) along with the ZnPc derivatives, well documented in literature were used to study a new concept called the red shift index (RsI). The concept is based on the empirical values of RsI of the different complexes in solvent media. Unequivocally, parameters used in this paper show strong correlations that are consistent with the results obtained. For instance, RsI of the complexes tend to increase as the refractive index, nD, and solvent donor, DN, of solvent increases. Photodegradation (photobleaching) quantum yield, ϕd measurements of these compounds show that they are highly photostable, ϕd (0.03–0.33 × 10−5). The triplet quantum yield, ϕT (0.40–0.53) and the triplet lifetime, τT (610–810 μs) are within the typical range for metallophthalocyanines in DMSO. The photosensitisation efficiency, SΔ, is relatively high for all the molecules (0.74–0.90).
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  • Date Issued: 2010

“Un-silencing queer Nigeria”: Representations of queerness in contemporary Nigerian fiction

  • Authors: Akram, Tahzeeb
  • Date: 2021-10-29
  • Subjects: Heterosexism in literature , Patriarchy in literature , Homophobia in literature , Sexual minorities in literature , Nigerian literature 21st century History and criticism , Queer theory Nigeria , Gender identity Law and legislation Nigeria , Gender identity Religious aspects , Sexual minorities Nigeria Social conditions , Nigeria. Same Sex Marriage (Prohibition) Act, 2013
  • Language: English
  • Type: Master's theses , text
  • Identifier: http://hdl.handle.net/10962/190668 , vital:45016
  • Description: This thesis analyses contemporary queer Nigerian fiction, particularly queer representations regarding law, religion and culture in Nigeria’s heteropatriarchal and queerphobic society. I explore a number of authors’ use of different literary forms and platforms to promote and represent non-conforming genders and sexualities in queerphobic Nigeria. These narratives show queer people navigating the heteronormative society vis-à-vis marriage, family, intimacy, work, violence and rights activism. I draw on Western and African gender and queer theories for the concepts, definitions and critical terminologies used in this thesis. African queer theorists and activists are highlighted for their reclaiming queer history from among the early records in Africa as well as contemporary queer Nigerian literature and activism. Religion and queerness are crucial themes in Chinelo Okparanta’s same sex women’s novel, Under the Udala Trees. Using queer African Christian theology against Nigeria’s conservative socio-religious setting, I demonstrate that queerness is not a threat to Nigerian’s Christian faith, and that mutual coexistence of queer sexuality and Christianity advances queer rights in that society. Nnanna Ikpo’s Fimí Sílẹ̀ Forever: Heaven gave it to me’s problematises heteronormative masculinities and the manufacturing of heteropatriarchy and queer masculinities in Nigeria. I examine the protagonists who are both victims of and perpetrators in their queerphobic society. The socio-legal focus I employ examines the impact of the 2014 Same Sex Marriage Prohibition Act on Nigeria’s already marginalised and oppressed queer community. There are vast opportunities for queer Nigerian artists to create, publish and promote queer identities in the safe and enabling space of online platforms via physical distancing between the queer community and the queerphobic society. From the digitally published 14: An Anthology of Queer Art’s two volumes, five short stories are analysed regarding different forms of intimacies in queer men’s relationships. These queer contemporary fiction writers offer complex representations of queerness within Nigeria’s heteropatriarchal and queerphobic society that polices non-normative bodies through religion, culture and the law. Such literary texts, digital literary platforms and activism vitally provide queer Nigerians a progressive space to assert queer presence, voices lives and rights to educating and re-socialising their society towards humaneness. , Thesis (MA) -- Faculty of Humanities, Literary Studies in English, 2021
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  • Date Issued: 2021-10-29

Behavioural activities and chemical composition of fresh leaf essential oil of Plectranthus aegyptiacus from Southwest Nigeria in mice

  • Authors: Akuegbe, Enimeya Dressman , Oyemitan, Idris Ajayi , Oyedeji, Opeoluwa , Ogunlowo, Ifeoluwa Isaac , Miya, Gugulethu Mathew , Oyedeji, Adebola
  • Date: 2021-6
  • Subjects: Acute toxicity testing , Carvacrol , Essential oil , Behaviour modification , Plectranthus
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/11260/6506 , vital:46434 , ("https://doi.org/10.30574/gscbps.2021.14.2.0030")
  • Description: This study determined the chemical composition of essential oil obtained from fresh leaf of Plectranthus aegyptiacus, and evaluated it for novelty-induced behavioural (NIB) and determine its mechanism(s) of action in mice. The oil was hydro-distillated, and analyzed using gas chromatography-mass spectrometry. The effects of the oil (50, 100 and 150 mg/kg; i.p., n=6) on novelty-induced behavioural was assessed using open field test and head dipping on hole board. Probable mechanism(s) were evaluated using antagonists: flumazenil, naloxone and cyproheptadine at 2 mg/kg each, atropine and yohimbine at 5 mg/kg and 1 mg/kg respectively. The LD50 values obtained were 2154 and 490 mg/kg for oral and intraperitoneal routes respectively. The oil (50, 100 and150 mg/kg) significantly (p less 0.05, 0.01 and 0.01) inhibited all NIB and head dips. Flumazenil significantly (p less than 0.05) reversed the effect of the oil on NIB; atropine, naloxone and cyproheptadine significantly (p less than 0.01, 0.01 and 0.001) potentiated inhibitory effect on NIB respectively, while yohimbine showed no significantly effect. The analyzed oil showed 61 compounds, and the major compounds were carvacrol, germacrene-D, p-cymene and [1,1'-Bicyclopentyl]-2,2'-diol. The study concluded that the oil possessed central nervous system depressant activity, which could be mediated mainly through augmentation of GABAergic neurotransmission, while cholinergic-(muscarinic), adrenergic and serotonergic pathways may be involved.
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  • Date Issued: 2021-6

Effect of pomegranate (Punica granatum L) peel powder meal on growth performance, gut integrity, haemato-biochemical indices, meat, and bone quality of broiler chickens

  • Authors: Akuru, Eunice Amaka https://orcid.org/0000-0002-3093-0247
  • Date: 2022-04
  • Subjects: Broilers (Chickens) , Meat -- Quality
  • Language: English
  • Type: Doctoral theses , text
  • Identifier: http://hdl.handle.net/10353/23611 , vital:58218
  • Description: The objective of the current study was to investigate the overall response of broiler birds to varying dietary levels of pomegranate (Punica granatum L) peel powder meal (PPPM). A total of 432-day-old Cobb 500 broiler chicks were randomly divided into six experimental groups of four replications with 18 birds per replicate in a completely randomized design (CRD). The birds were fed isonitrogenous and isocaloric experimental diets designated as: T1-control diet with 0percent additives (negative control; NEGCON); T2- control diet supplemented with α-tocopherol acetate at 200g per ton (positive control; POSCON): T3, T4, T5 and T6-control diet supplemented with 2, 4, 6 and 8g/kg PPPM (PPPM2, PPPM4, PPPM6, PPPM8). The phytochemical, nutritional and antioxidant properties of the pomegranate peel powder were determined. Results showed that the South African-grown pomegranate peel (“Wonderful” variety) had rich protein and trace mineral contents. Higher (p < 0.05) antioxidant and hepatic anti-lipid peroxidative activities were recorded in the ethanol and acetone extracts than the water extract, whereas the three extracts had no toxic effects on liver and kidney cells (p > 0.05). The dietary effects of PPPM supplementation on growth performance, digestibility, carcass, and organ weight indices of Cobb 500 birds were determined. The POSCON diet enhanced (p < 0.05) feed conversion ratio (FCR) at week 3. The average final body weight and average daily weight gain were highest (p < 0.05) in birds fed PPPM2 and PPPM4 diets, whereas birds fed PPPM2 diet had enhanced (p < 0.05) FCR and protein efficiency ratio when compared with birds on POSCON. Thigh and breast weights were highest (p < 0.05) in birds on PPPM4 and PPPM8 diets, whereas birds fed PPPM4 diet had enhanced (p < 0.05) nutrient digestibility compared with those on POSCON. The antioxidant status and breast meat quality of Cobb 500 broiler birds fed diets supplemented with PPPM were determined. Meat from birds fed PPPM8 diet had the highest (p < 0.05) thawing loss, while cooking loss was lowest (p < 0.05) in the PPPM2 group. The highest (p < 0.05) ability to scavenge ABTS [(2, 2-azinobis (3ethylbenzothiazoline-6 sulfonic acid))] radical cation (ABTS+) was recorded in the PPPM2 and PPPM4 meat while PPPM8 meat had increased (p < 0.05) catalase activity. The fatty acid composition, oxidative status, and drip loss in breast meat of Cobb 500 broiler birds fed graded levels of PPPM was determined. Meat from birds fed PPPM4 diet had the lowest (p < 0.05) margaric (C17:0) and arachidic (C20:0) acids, while meat from birds fed PPPM8 diet had higher (p < 0.05) levels of eicosadenoic (C20:2, n-6) and arachidonic (AA, 20:4) acids. The POSCON had higher (p < 0.05) ability to reduce TBARS levels in meat on day-1 and day-16 of storage than the NEGCON and PPPM diets, whereas TBARS levels were lowest (p < 0.05) in PPPM6 meat on day-16. The gut pH, histology, haematology, serum-biochemical indices, and bone quality parameters of Cobb 500 broiler birds fed diets supplemented with PPPM was determined. Birds fed POSCON, PPM2 and PPPM4 diets had the lowest (p < 0.05) pH in the duodenum, jejunum, and caecum, whereas duodenal pH values were lowest (p < 0.05) in birds fed PPPM2 and PPPM4 diets compared with birds on NEGCON. Birds fed PPPM4 diet had the highest (p < 0.01) duodenal, jejunal and ileal villi height (VH), and the highest (p < 0.01) VH to crypt depth (CD) ratio in the duodenum, jejunum, and ileum. The lowest (p < 0.05) CD in the duodenum, jejunum and ileum was also recorded in birds fed PPPM4 diet. Birds fed PPPM8 diet had higher (p < 0.05) values for white blood cell count, red blood cell count, haemoglobin concentration and packed cell volume, whereas the lowest (p < 0.05) concentration of serum aspartate transaminase was recorded in birds fed PPPM4 diet. Birds on PPM4 diet had longer (p < 0.05) bones. Bone weight and bone breaking strength were highest (p < 0.05) in birds fed PPPM8 diet. Tibia zinc and iron concentrations increased as the inclusion levels of pomegranate peel powder meal increased. It was concluded that broiler birds require 4 g/kg pomegranate peel powder for enhanced growth performance, nutrient digestibility, gut histology, quality, and antioxidant enzyme activity of meat, whereas 8 g/kg pomegranate peel powder meal supplementation is required for enhanced heamato-biochemical indices, bone quality, fatty acid composition and lipid peroxidative parameters in broiler birds. , Thesis (PhD) -- Faculty of Science and Agriculture, 2022
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  • Date Issued: 2022-04

Prevalence and factors associated with suicidal ideation amongst college students in the Nelson Mandela Bay Municipality, South Africa

  • Authors: Alabi, Adeyinka A , Oladimeji, Olawumi K , Adeniyi, Oladele Vincent
  • Date: 2021
  • Subjects: Suicidal behaviour Education (Higher) Students Article
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/11260/7235 , vital:53093 , xlink:href="https://doi.org/10.4102/safp.v63i1.5195"
  • Description: Background: Suicidal behaviour amongst college students constitutes a significant social and public health problem globally. This study determined the prevalence and associated factors of suicidal ideation amongst students of higher education in the Nelson Mandela Bay Municipality (NMBM), South Africa. Methods: In this institution-based cross-sectional study, a multistage cluster sampling of 826 participants, drawn from a college in NMBM, was conducted from January to March 2020. Data were collected with a standardised self-administered questionnaire. Multivariable logistic regression analysis was used to identify the factors associated with suicidal ideation. Results: Participants’ ages ranged from 18 to 24 years, with a mean age of 20.49 years (standard deviation, 1.88 years). The lifetime prevalence of suicidal ideation and plans in the preceding 12 months were 24.5% and 9.6%, respectively. The odds of suicidal ideation were higher in students who experienced bullying (adjusted odds ratio [AOR], 1.89; 95% confidence interval [CI], 1.35–2.65), mental illness (AOR, 1.89; 95% CI, 1.35–2.65), a history of sexual assault (AOR, 2.50; 95% CI, 1.20–5.21) and experience of sexual assault by or to a close family member (AOR, 1.69; 95% CI, 1.01–2.82). Underlying chronic illness was associated with a twofold risk for suicidal ideation in both sexes. Conclusion: About a quarter of the students sampled at the college had experienced suicidal ideation and some had had suicidal plans in the preceding 12 months. Screening for the identified risk factors amongst the student population coupled with prompt interventions would mitigate the risk of suicide in the study population. Keywords: suicidal behaviour; suicidal plans; higher education; students; South Africa.
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  • Date Issued: 2021

Pharmacological, toxicological and phytochemical evaluation of helichrysum petiolare hilliard & b.l. burtt - an indigenous plant traditionally used in the treatment of diabetes in the eastern cape province of South Africa

  • Authors: Aladejana, Adebowale Emmanuel https://orcid.org/0000-0003-1871-926X
  • Date: 2022-04
  • Subjects: Diabetes -- Alternative treatment , Traditional medicine , Medicinal plants
  • Language: English
  • Type: Doctoral theses , text
  • Identifier: http://hdl.handle.net/10353/22787 , vital:52755
  • Description: Diabetes mellitus is one of the leading causes of death in South Africa, and it has already placed significant stress on the country’s health sector and economy. The orthodox hypoglycaemic drugs are not only ineffective in the management of the disease and its complications, but they also possess unwanted side effects. The need for alternative non-toxic drugs is therefore imperative. Various studies have listed several medicinal plants that can be successfully used in the herbal treatment of diabetes and have investigated them for their anti-diabetic potentials in vivo and/or in vitro. Out of the different potential herbal species, plants belonging to the Asteraceae family possess highly potent hypoglycaemic properties with negligible toxicities. Five Asteraceae plants widely used in different parts of South Africa for the treatment of diabetes were reviewed. The review provided an update of scientific evidence on the hypoglycaemic properties of the plants. However, Helichrysum petiolare was studied extensively in this study for its antidiabetic activity H. petiolare has been listed in many ethnobotanical surveys as a plant with potent hypoglycaemic potential, this, however, has not been properly verified in scientific literature and there has hardly been any study on the essential oil and nutritional composition, and antioxidant, antidiabetic, and cytotoxicity potentials of the plant. The effects of hydro-distillation (HD) and solvent-free microwave extraction (SFME) methods on the chemical constituents of H. petiolare-derived essential oils were evaluated. The SFME method had a higher yield of essential oil than the HD. There were substantial amounts of monoterpenes, monoterpene alcohols, sesquiterpenes, and sesquiterpene alcohols in both essential oils obtained, but these compounds were more profound in the SFME derived essential oil which has 62 compounds compared to the 52 derived through HD. The SFME derived essential oil can therefore be said to be of better quality than the HD method. The compounds obtained in the essential oils have high pharmaceutical and cosmetic value, and as observed in this study, their quantity is dependent on the method of extraction (Ibáñez and Blázquez, 2021; Kaur et al., 2021). The proximate analysis of the whole plant of H. petiolare showed high levels of Acid Detergent Fibre (ADF), vitamins (A, C and E), Neutral Detergent Fibre (NDF), and minerals. The high ADF level is believed to be responsible for the low energy, fat and carbohydrate levels observed in the study. The result showed a high level of oxalate and therefore suggests cooking of the plant before human consumption. Overall nutrition and mineral compositions of the plant showed that H. petiolare is immensely rich in vital nutrients that are of great importance to health and metabolism; these nutrients are suggested to be partly responsible for the plant’s useful medicinal properties. The phytochemical contents of the acetone (ACQ), ethanol (ETQ), and boiled (BAQ) and cold (CAQ) aqueous whole-plant extracts of Helichrysum petiolare were determined using standard phytochemical reaction methods. ABTS, DPPH, NO and TAC assays were used to evaluate their antioxidant properties. The highest total phenolic content (212,963 mg/g) was reported in the BAQ extract, while the ETQ had the highest flavonoid (172.393 mg/g) and proanthocyanidin contents (65.855 mg/g). Alkaloids, flavonols, and saponin were highest in the ACQ extract, while the CAQ had the lowest phytochemical content. Among the extracts, the BAQ had the highest DPPH•+ (IC50 0.02 mg/mL) and ABTS•+ (IC50 0.07) inhibition capacities, while the ETQ exhibited the highest NO• Inhibition (IC50 0.41 mg/mL) and TAC (IC50 0.19 mg/mL). These findings justify the use of H. petiolare in traditional medicine and further recommend the ETQ and BAQ extracts of the plant as more effective extracts for medicinal treatment. The hepatotoxicity (cytotoxicity, mitotoxicity and lipotoxicity) potential of the BAQ, CAQ and ETQ extracts of Helichrysum petiolare was evaluated using standard procedures. The results showed negligible BAQ and CAQ cytotoxicities, which were further, corroborated by stability in the mitochondrial membrane potentials and were congruent with the CAQ and BAQ results for steatosis and phospholipidosis. The data suggested favourable CAQ and BAQ toxicity profiles with limited risks for hepatotoxicity. The ETQ extract, however, showed significantly high levels of cytotoxicity and lipotoxicity, and a low level of mitotoxicity. Our result suggested a potential risk of the ETQ extract for hepatotoxicity but appears partly independent of direct mitochondrial involvement. Glucose uptake assay showed significantly increased glucose uptake in the BAQ and CAQ treated L6 and C3A cell lines. The CAQ extract enhanced glucose uptake more in the L6 myocytes than in the C3A cell-lines hepatocytes. The BAQ extract showed higher levels of inhibition on α–amylase and α-glucosidase activities as compared to CAQ. The BAQ and CAQ extracts of H. petiolare may, therefore, contain pharmacologically active and relatively non-toxic hypoglycaemic chemicals, which may be effective substitutes in the treatment of diabetes mellitus. This study provides up to date scientific information on the use of H. petiolare in the treatment of diabetes mellitus in the Eastern Cape of South Africa. It justifies the use of this plant in herbal medicine and sheds more light on its previously vaguely understood nutritional and medicinal potentials. More studies, however, need to be done to isolate, identify and purify the constituent bioactive compound(s). Their dosage of application and mode of action also needs to be understood. , Thesis (PhD) -- Faculty of Science and Agriculture, 2022
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  • Date Issued: 2022-04

An educational intervention for professional nurses on the use of surgical attire in the prevention of surgical site infections in the operating theatres

  • Authors: Alayemi, Joshua
  • Date: 2020-04
  • Subjects: Surgical wound infections--Prevention , Surgery, Aseptic and antiseptic --South africa , Operating room nursing--South Africa
  • Language: English
  • Type: Master's theses
  • Identifier: http://hdl.handle.net/10948/55522 , vital:52754
  • Description: Infection control and prevention is an issue that is of utmost importance to every health practitioner, including professional nurses, as patients who undergo surgeries could develop sepsis, leading to failure of multiple organs and possibly death. Surgical site infections acquired from operating theatres are often introduced when there is lack of application of and adherence to the necessary control measures, sterile principles and techniques, including the appropriate use of surgical attire. This study aimed to contextualize, implement and evaluate an existing educational intervention regarding the use of surgical attire in operating theatres, in order to establish whether the educational intervention enhanced the practices of professional nurses in operating theatres regarding the use of surgical attire. A quantitative research design, using a quasi-experimental two-group pre-test, post-test intervention approach was employed for the study. The study consisted of three phases. The study is underpinned by the Promoting Action on Research Implementation (PARiHS) framework. The research sample consisted of all professional nurses working in the public and private operating theatres in the Nelson Mandela Bay Municipality. Purposive sampling was used to select the hospitals in control (Hospitals 2 and 3) and intervention groups (Hospitals 4 and 5), ensuring an equal number of public and iv private hospitals in each group. Data was collected through self-administered pre- and post-questionnaires. An existing educational intervention based on the Association of Perioperative Registered Nurses (AORN’s) guidelines was contextualized through review by three professional nurses with a specialty in operating theatre. The educational intervention was implemented for the intervention group, while the control group only received the summary of the AORN guidelines. Reliability and validity were ensured through the conduct of a pilot study, and expert review by three professional nurses with a specialty in operating theatre in order to check the validity and reliability of the data collection instrument and educational intervention. This means that the educational intervention had a positive effect in terms of improving the professional nurses’ practices on the use of surgical attire to prevent surgical site infections in operating theatres. , Thesis (MA) -- Faculty of Health Sciences Clinical Care and Medicinal Science, 2020
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  • Date Issued: 2020-04

Food on the Table: Human Responses and Changing Coastal Fisheries in Solomon Islands

  • Authors: Albert, Simon , Aswani, Shankar , Fisher, Paul L , Albert, Joelle
  • Date: 2015
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/421887 , vital:71893 , xlink:href="https://doi.org/10.1371/journal.pone.0130800"
  • Description: Globally the majority of commercial fisheries have experienced dramatic declines in stock and catch. Likewise, projections for many subsistence fisheries in the tropics indicate a dramatic decline is looming in the coming decades. In the Pacific Islands coastal fisheries provide basic subsistence needs for millions of people. A decline in fish catch would therefore have profound impacts on the health and livelihoods of these coastal communities. Given the decrease in local catch rates reported for many coastal communities in the Pacific, it is important to understand if fishers have responded to ecological change (either by expanding their fishing range and/or increasing their fishing effort), and if so, to evaluate the costs or benefits of these responses. We compare data from fish catches in 1995 and 2011 from a rural coastal community in Solomon Islands to examine the potentially changing coastal reef fishery at these time points. In particular we found changes in preferred fishing locations, fishing methodology and catch composition between these data sets. The results indicate that despite changes in catch rates (catch per unit effort) between data collected in 2011 and 16 years previously, the study community was able to increase gross catches through visiting fishing sites further away, diversifying fishing methods and targeting pelagic species through trolling. Such insight into local-scale responses to changing resources and/or fisheries development will help scientists and policy makers throughout the Pacific region in managing the region’s fisheries in the future.
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  • Date Issued: 2015

Cost-effective methods for accurate determination of sea level rise vulnerability: A Solomon Islands example

  • Authors: Albert, Simon , Abernethy, Kirsten , Gibbes, Badin , Grinham, Alistair , Tooler, Nixon , Aswani, Shankar
  • Date: 2013
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/422708 , vital:71971 , xlink:href="https://doi.org/10.1175/WCAS-D-13-00010.1"
  • Description: For millions of people living along the coastal fringe, sea level rise is perhaps the greatest threat to livelihoods over the coming century. With the refinement and downscaling of global climate models and increasing availability of airborne-lidar-based inundation models, it is possible to predict and quantify these threats with reasonable accuracy where such information is available. For less developed countries, especially small island states, access to high-resolution digital elevation models (DEMs) derived from lidar is limited. The only freely available DEMs that could be used for inundation modeling by these nations are those based on data from the Shuttle Radar Topography Mission (SRTM). These data, with a horizontal resolution of ≈90 m and a vertical accuracy of ±5–10 m, are generally unsuitable for local-scale planning and adaption projects. To address this disparity, low-cost ground-based techniques were tested and applied to accurately determine coastal topography in the Solomon Islands. This method had a significantly improved vertical accuracy (±2 cm) and was readily learned by local community members, who were able to independently map and determine the vulnerability of their costal community to inundation from sea level rise. For areas where lidar is not economically viable, this method is intended to provide an important balance of cost, simplicity, accuracy, and local participation that can assist remote coastal communities with coastal planning decisions. The method can enhance local capacity and arguably promotes more meaningful local engagement in sea level rise planning and adaptation activities.
  • Full Text:
  • Date Issued: 2013

The influence of citrus orchard age on the ecology of entomopathogenic fungi and nematodes

  • Authors: Albertyn ,Sonnica , Moore, Sean D , Marsberg, Tamryn , Coombes, Candice A , Hill, Martin P
  • Date: 2020
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/417545 , vital:71462 , xlink:href="https://hdl.handle.net/10520/ejc-cristal-v10-n1-a7"
  • Description: A three-year survey of the ecology of entomopathogenic nematodes (EPN) and entomopathogenic fungi (EPF) was undertaken on soils from citrus orchards of different ages to determine the influence of orchard age on the ecology of entomopathogenic fungi and nematodes. The influence of mulch and irrigation method on the occurrence of EPN and EPF was also determined. Most of the isolates recovered (n = 810) were Beauveria sp. (87.88% of all isolates), followed by Metarhizium sp. (11.87% of all isolates). Only 0.24% of soil samples collected during this study tested positive for EPN. All EPN isolates recovered were Heterorhabditis bacteriophora. No significant differences in EPF occurrence were recorded between orchards under drip and micro-sprinkler irrigation. EPF occurrence was significantly lower (P = 0.016) in orchards covered by mulch (31.85% ± 2.07% occurrence) than in orchards with no covering (38.57% ± 1.57% occurrence). EPF occurrence of 40.33 ± 2.13% was highest in non-bearing orchards, followed by mature orchards (nine years or older) (36.76 ± 2.05% of samples) with the lowest EPF occurrence of 25.30 ± 2.02% reported in juvenile orchards (four to eight years old). Juvenile orchards sustain significantly less EPF than mature and non-bearing orchards because of the combined negative impact of less favourable environmental conditions (lower shade density) and fungicide applications.
  • Full Text:
  • Date Issued: 2020

The influence of citrus orchard age on the ecology of entomopathogenic fungi and nematodes

  • Authors: Albertyn, Sonnica , Moore, Sean D , Marsberg, Tamryn , Coombes, Candice A , Hill, Martin P
  • Date: 2021
  • Subjects: To be catalogued
  • Language: English
  • Type: text , article
  • Identifier: http://hdl.handle.net/10962/417790 , vital:71486 , xlink:href="https://doi.org/10.1080/09583157.2020.1830949"
  • Description: A three-year survey of the ecology of entomopathogenic nematodes (EPN) and entomopathogenic fungi (EPF) was undertaken on soils from citrus orchards of different ages to determine the influence of orchard age on the ecology of entomopathogenic fungi and nematodes. The influence of mulch and irrigation method on the occurrence of EPN and EPF was also determined. Most of the isolates recovered (n = 810) were Beauveria sp. (87.88% of all isolates), followed by Metarhizium sp. (11.87% of all isolates). Only 0.24% of soil samples collected during this study tested positive for EPN. All EPN isolates recovered were Heterorhabditis bacteriophora. No significant differences in EPF occurrence were recorded between orchards under drip and micro-sprinkler irrigation. EPF occurrence was significantly lower (P = 0.016) in orchards covered by mulch (31.85% ± 2.07% occurrence) than in orchards with no covering (38.57% ± 1.57% occurrence). EPF occurrence of 40.33 ± 2.13% was highest in non-bearing orchards, followed by mature orchards (nine years or older) (36.76 ± 2.05% of samples) with the lowest EPF occurrence of 25.30 ± 2.02% reported in juvenile orchards (four to eight years old). Juvenile orchards sustain significantly less EPF than mature and non-bearing orchards because of the combined negative impact of less favourable environmental conditions (lower shade density) and fungicide applications.
  • Full Text:
  • Date Issued: 2021

Schema therapy for anorexia nervosa: an intensive systematic individual case study

  • Authors: Alexander, Graham
  • Date: 2021-10-29
  • Subjects: Eating disorders , Anorexia nervosa , Anorexia nervosa Treatment , Anorexia nervosa Case studies , Schema-focused cognitive therapy , Anorexic overcontroller , Interpretative phenomenological analysis (IPA)
  • Language: English
  • Type: Doctoral theses , text
  • Identifier: http://hdl.handle.net/10962/196082 , vital:45724 , DOI https://doi.org/10.21504/10962/196082
  • Description: Developed more than three decades ago, schema therapy (ST) was born out of a need for a more effective way of working with difficult and challenging cases where patients were clearly unresponsive to the existing short-term cognitive therapies. While anchored in the primary theoretical orientation of cognitive therapy, ST has carefully integrated techniques and principles from attachment and object-relations therapies, as well as humanistic, gestalt and experiential therapies. The mode model emphasises the concept of “multiplicity” in terms of which the self is functionally divided into parts or schema modes. For a little more than a decade there has been growing interest amongst researcher-clinicians in the application of ST for the treatment of eating disorders (EDs) (Waller, et al., 2007; Simpson, 2012; Edwards, 2015; Munro et al., 2016; Simpson, 2016; Munro et al., 2016). While multivariate studies can provide quantifiable evidence for the efficacy of ST for treating EDs, systematic case-based research offers a means of engaging in an intensive analysis and description of the complex and subtle processes that unfold over time in a real-life therapeutic environment (Edwards et al., 2004; Yin, 1994). This research method also provides an opportunity for the refining of the clinical treatment model as well as its testing. Ten participants were assessed and treated with schema therapy. However, because of the large amount of data gathered, a decision was made to write up only one as an intensive systematic individual case study. Alison, an elderly woman with a longstanding history of AN who had been largely unresponsive to considerable previous therapies, received 100 ST sessions over a two-year period and showed a very positive response. The many challenges that arose and the way these were addressed within the ST framework provide an in-depth account of the application of the ST mode model for the treatment of AN. This is presented in a detailed therapy narrative. After results of the quantitative measures are provided, the next three chapters address three interpretative questions pertaining to the Healthy Adult/Vulnerable Child dyadic relationship, the processes of working with the Angry Child mode, and the conceptualising of an AN-specific coping mode. Several conclusions are drawn about the strengths of the schema therapy model and its particular application to AN. Amongst these is the importance of having a comprehensive case conceptualisation that serves as a collaborative “road map” with which to negotiate the unfolding collaborative therapeutic process. Another is the identifying of the “Anorexic Overcontroller” as a stand-alone coping mode that clarifies the functions of AN to hinder schema-based emotional injury, but paradoxically, still denies the individual’s basic core needs being met. Such a conceptualisation significantly assisted in the suspension of anorexic behaviour. A further significant observation is how emotion-focused work (especially within the context of chair work and imagery) brought therapy to life and was particularly effective in mobilising the conflict between internal voices. Another outstanding feature is how the building of a strong Healthy Adult mode proved vital in the healing process and the development of patient autonomy. Finally, therapy revealed how central the establishment of a sturdy, warm and loving therapeutic relationship is, and how influential the resonance between the therapist and patient is in the outcome of treatment. , Thesis (PhD) -- Faculty of Humanities, Psychology, 2021
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  • Date Issued: 2021-10-29

The memory altar

Macroplastics in the environment: are they suitable habitats for macroinvertebrates in riverine systems?

  • Authors: Ali, Andrew Abagai
  • Date: 2023-10-13
  • Subjects: Uncatalogued
  • Language: English
  • Type: Academic theses , Master's theses , text
  • Identifier: http://hdl.handle.net/10962/424153 , vital:72128
  • Description: Emerging pollutants, such as plastics are threat to freshwater ecosystems, and may negatively impact riverine systems. They can modify riverine habitats and affect aquatic organism distribution and composition. Knowledge of how macroplastics alter riverine habitat heterogeneity, and their effects on macroinvertebrate assemblage structure is sparse, especially in Africa. This study examines the effect of hydraulic biotopes on the colonisation, establishment and succession patterns of macroinvertebrates on macroplastic and natural substrates based on the taxonomic and trait-based approach. Four experimental sites from minimally impacted upper reaches of the Buffalo, Kat, Kowie, and Swartkops Rivers in the Eastern Cape of South Africa were selected for the deployment of plastic substrates. Plastics materials, including polyethylene terephthalate (PET) bottles and natural substrate composed of stone and vegetation, were used to formulate three substrate groups: Group 1: 100% natural substrates (NS), Group 2: 50% natural substrates and 50% plastic material (NP), and Group 3: 100% plastic materials (PD). These substrates were placed in litter bags of equal dimension (25 cm by 35 cm, with 2.5 cm mesh) and deployed randomly in three hydraulic biotopes (pools, riffles, runs) over a period of 180 days (October 2021 to April 2022). A total of 216 substrate bags, 54 bags per substrate were deployed per site in the four experimental sites. Twelve bags from each substrate group were retrieved at an interval of 30 days beginning on day 30 after deployment, and analysed for the establishment of macroinvertebrate communities. Based on composite hydraulic biotope data, Simpson index was significantly higher (P < 0.05) for macroinvertebrate assemblage structure on the 50% and 100% macroplastic substrate groups compared to natural substrates. With the exception of Tabanidae, Glossosomatidae, and Psephenidae, all macroinvertebrate taxa recorded showed non-significant positive correlations with all three substrate groups. However, Tabanidae, Glossosomatidae, and Psephenidae showed significant positive correlation with the 100% natural substrates, 50% plastic substrates and 100% plastic substrates, respectively. The parsimony analysis reveal that, within 30 days, all substrate groups underwent similar succession, with high abundance of pioneer taxa which increased on days 60 and 90, and then decreased from days 120 to 180. For the the pool biotope, Shannon and Simpson indices were significantly higher (P < 0.05) for the macroinvertabrates collected over the natural substates compared with those collected on the macroplastic substrate groups. However, in the riffle and run biotopes, all diversity indices were similar for all substrate groups and no statistically significant difference was observed. Statistically significant higher values for taxonomic richness, diversity, and evenness were found on day 30 to 90 for the riffle biotopes, and day 30 to 60 for the run biotopes. The run biotope presented temporal statistical significant variability in taxonomic composition with different macroinvertebrate communities recorded on days 30 and 60 compared with days 90 to 180. However, in pools and riffles, no temporal variation was observed in the taxonomic composition of macroinvertebrates on all three substrate groups. The trait-based fuzzy correspondence analysis revealed differential spatial-temporal distribution of macroinvertebrate traits on all three substrate group. The early colonisers i.e. day 30 – 60, were dominated by group of taxa characterised by medium (>10 – 20 mm) and large (20 > 40) body size, flat body, collector-gatherers, free-living, and predators. The late colonisers, collected mainly on day 150 and 180 were dominated by taxa with a preference for high flow velocity (0.3 - 0.6 m/s), permanent attachment, and filter-feeding mode. Traits such as oval and flat body shape, medium body size (>10 - 20 mm), skating and clinging/climbing mobility, temporal attachment, shredders, predators, prey, and plastron and spiracle respiration showed positive correlation with the 100% macroplastic substrates. Filter feeding, crawling, permanent attachment, a preference for fast velocity (0.3-0.6 m/s), and coarse particle organic matter were positively correlated with the 50% macroplastic substrates. Overall, the results provided critical insights on the impact of macroplastics on the assemblage structure of biological communities by acting as suitable habitats in stream ecosystems. The study elucidated the role of traits of aquatic organisms in mediating the colonisation of plastics substrates, providing insights into the impact of plastics proliferation on riverine ecosystem functioning. Furthermore, the finding provides a baseline insight into the influence of hydraulic biotopes on the colonisation and establishment of macroinvertebrates on macroplastic acting as artificial riverine habitat. , Thesis (MSc) -- Faculty of Science, Institute for Water Research, 2023
  • Full Text:
  • Date Issued: 2023-10-13

Associations between contraceptive use, physical activity, depression, and quality of life among women of childbearing age in Akure South Local Government area of Ondo State, Nigeria

  • Authors: Alimi, Olabisi Ganiyat
  • Date: 2023-10-13
  • Subjects: Uncatalogued
  • Language: English
  • Type: Academic theses , Master's theses , text
  • Identifier: http://hdl.handle.net/10962/424210 , vital:72133
  • Description: Background: Population experts and policymakers are concerned about Nigeria's rapid annual population growth due to the country's high birth rate which was 5.3 births per woman in 2018. Fear of the side effects of modern contraceptives among Nigerian women contributes to the low rate of contraceptive use, which was reported to be 17% and 37% among married and sexually active unmarried women, respectively. Which is a significant cause of the high birth rate. Although the side effects of modern contraceptives on women's clinical and physiological variables are well known, studies examining the associations between contraceptive use and physical and psychosocial variables such as physical activity (PA), depression, and quality of life (QoL) in non-athletic Nigerian women of reproductive age are scarce. This study aimed to examine the associations between contraceptive use, PA, depression, and QoL among non-athletic women of childbearing age in Akure South Local Government, Ondo State, Nigeria. Methods: In a descriptive cross-sectional study, 646 women of childbearing age were recruited using the multistage sampling technique. The data of 496 current contraceptive users and 146 non-users were analysed, as 4 respondents did not respond regarding current contraceptive use status. The Global PA Questionnaire (GPAQ), Beck’s Depression Inventory (BDI) and World Health QoL Organization Quality of Life Brief (WHOQoL BREF) were used to assess respondents’ scores/levels of PA, depression and health-related quality of life (HRQoL). The GPAQ, BDI, and WHOQOL scores were compared between contraceptive users and non-users using non-parametric Quade Analysis of Covariance while age, married status, tribe, religion, and occupation were included covariates. PA, sedentary behaviour (SB), and BDI scores were categorized using guidelines. Contraceptive use/practice was the outcome variable. Pearson's chi-square test bivariate analysis and a multivariate logistic model were used to identify factors associated with contraceptive use (users and non-users). Crude and adjusted odds ratios and their confidence intervals were calculated to determine the significance of the association. The regression model was adjusted for age, marital status, religion, tribe, highest education level, occupation, awareness of contraceptives, current use, lifetime use, type, class, and duration of current contraception. “Statistical significance was set at p < 0.05. Results: The mean age of the respondents was 29.73±6.10 years. The contraceptive users and non-users were not significantly different regarding their ages (p = 0.135), marital status (p = 0.245), highest education (p = 0.444), occupation (p = 0.238), and tribe (p = 0.192). The respondents’ lifetime and point prevalence of contraceptive uptake was 93.6% and 77.3%, respectively, while 72 (12.8%) reported experiencing contraception-related side effects. Of the 496 respondents who currently practice contraception, 146 (29.4%) were hormonal contraceptive users. The majority of the respondents had moderate and mild levels of PA (48.5%) and depression (51.4%), respectively, and a significantly higher proportion of contraceptive users had minimal and moderate depression levels than the non-users (p = 0.018). The contraceptive users demonstrated significantly higher median scores of BDI (p = 0.02), Physical health QoL (p < 0.001), environment QoL (p = 0.033) and overall QoL (0.004) than the non-users. Hormonal contraceptive users had significantly higher median PA walking/bicycling scores than non-hormonal users (p = 0.014). Respondents with mild and moderate depression levels had higher odds of being contraceptive users than those with minimal depression (AOR = 3.12, 95% CI = 1.43 – 6.80, p = 0.04 and 4.67, 95% CI = 1.92 – 11.36, p = 0.001 respectively). Conclusion: Contraceptive use is negatively associated with depression but positively related to Physical health, environment and overall domains of HRQoL. Healthcare professionals should consider women's mental and emotional condition while advising on family planning for optimal HRQoL. , Thesis (MSc) -- Faculty of Science, Human Kinetics and Ergonomics, 2023
  • Full Text:
  • Date Issued: 2023-10-13
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