An illustrated booklet for reinforcing community health worker knowledge of tuberculosis and facilitating patient counselling:
- Authors: Okeyo, Ida L A , Dowse, Roslind
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156585 , vital:40028 , https://phcfm.org/index.php/phcfm/article/view/1687/2559
- Description: Community health workers (CHWs) have facilitated the move to decentralize tuberculosis (TB) management, but lack access to information appropriate both for personal use and in patient interaction and education. To explore the impact of a pictorial-based TB booklet on reinforcing CHW knowledge and facilitating patient counselling.
- Full Text:
- Date Issued: 2018
Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[(N-cycloalkylbenzamido)methyl]-2-quinolones as potential HIV-1 integrase inhibitors
- Authors: Sekgota, Khethobole C , Majumder, Swarup , Isaacs, Michelle , Mnkandhla, Dumisani , Hoppe, Heinrich C , Khanye, Setshaba D , Kriel, Frederik H , Coates, Judy , Kaye, Perry T
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66178 , vital:28913 , https://doi.org/10.1016/j.bioorg.2017.09.015
- Description: publisher version , A practicable six-step synthetic pathway has been developed to access a library of novel 3-[(N-cycloalkylbenzamido)methyl]-2-quinolones using Morita-Baylis-Hillman methodology. These compounds and their 3-[(N-cycloalkylamino)methyl]-2-quinolone precursors have been screened as potential HIV-1 integrase (IN) inhibitors. A concomitant survey of their activity against HIV-1 protease and reverse-transcriptase reveals selective inhibition of HIV-1 IN.
- Full Text: false
- Date Issued: 2017
Assessment of some variables affecting the blanching activity of betamethasone 17-valerate cream
- Authors: Magnus, Ashley D , Haigh, John M , Kanfer, Isadore
- Date: 1980
- Language: English
- Type: text , Article
- Identifier: vital:6396 , http://hdl.handle.net/10962/d1006320
- Description: The effect of concentration and occlusion time on the ability of Betnovate ® cream (betamethasone 17-valerate 0.1%) to produce skin blanching was assessed. Generally, increased concentration or occlusion time produce and increase in the degree of blanching observed, however, a plateau stage is eventually reached where no further increase of blanching occurs.
- Full Text:
- Date Issued: 1980
Auditing 2B
- Authors: Emslie, Denny , Hanner, Lana
- Date: 2011-11
- Subjects: Auditing -- Examinations, questions, etc.
- Language: English
- Type: Examination paper
- Identifier: vital:17408 , http://hdl.handle.net/10353/d1009772
- Description: Auditing 2B, final assessment November 2011.
- Full Text:
- Date Issued: 2011-11
Base-metal mineralization in alkaline pyroclastics: the Regenstein Vent, South West Africa
- Authors: Ferreira, C A M , Jacob, Roger E , Marsh, Julian S
- Date: 1979
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/133220 , vital:36950 , https://hdl.handle.net/10520/AJA10120750_1123
- Description: Geochemical analysis of soil samples taken from the area underlain by the Regenstein alkaline diatreme indicated potential areas for Pb-Zn-Ag mineralization, and these were subsequently proved by drilling. The pipelike body, emplaced into quartzites of the Damara Supergroup, consists of lithic and volcanic breccias. The breccias have been intruded, first by phonolite dykes, and then by numerous bodies of alkaline mafic and ultramafic rocks.
- Full Text:
- Date Issued: 1979
Basic Chemistry: PAC 113F
- Authors: Soyaya, S.M , Mbentse, J Z
- Date: 2011-06
- Language: English
- Type: Examination paper
- Identifier: vital:17834 , http://hdl.handle.net/10353/d1010388
- Description: Basic Chemistry: PAC 113F, supplementary degree examination June 2011.
- Full Text: false
- Date Issued: 2011-06
Between a cushion and a risky conversation: ARTS LOUNGE reviewed
- Authors: Baasch, Rachel M
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147703 , vital:38662 , https://doi.org/10.1080/00043389.2011.11877155
- Description: On the fringe of the National Arts Festival, at a point of transition between Rhodes University campus and the commercial side of Grahamstown, the walls of a former home and former horse-stable, now a research house, reverberate with the strain of cross-disciplinary, site-specific collaboration. The ARTS LOUNGE made its first official appearance at the Grahamstown National Arts Festival (ViPPA Research Center, Rhodes University) from 30 June to 9 July 2011. The ten-day event was organised by the Visual and Performing Arts of Africa Research (ViPPA) team in collaboration with musicians, artists, writers, performers and members of the public.
- Full Text:
- Date Issued: 2017
Bioelectrocatalysis and surface analysis of gold coated with nickel oxide/hydroxide and glucose oxidase towards detection of glucose:
- Authors: Njoko, Nqobile , Louzada, Marcel , Britton, Jonathan , Khene, Samson M , Nyokong, Tebello , Mashazi, Philani N
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150071 , vital:38937 , https://doi.org/10.1016/j.colsurfb.2020.110981
- Description: The fabricating of metal oxide thin films onto conducting surfaces continues to grow and their potential applications as surfaces for biosensor applications is of paramount importance. The correct orientation of glucose oxidase redox enzymes yields very important biointerfaces capable of selectively detecting D-glucose as a measure of blood sugar for healthy and diabetic sick patients. The electrodeposition of redox enzymes, such as glucose oxidase enzymes, onto gold electrode surfaces pre-modified with nickel oxide was investigated in this work.
- Full Text:
- Date Issued: 2020
Biological activity of extracellular and intracellular polysaccharides from Pleurotus tuber-regium hybrid and mutant strains
- Authors: Bamigboye, Comfort Olukemi , Oloke, Julius Kola , Dames, Joanna Felicity
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69056 , vital:29376 , http://pubs.sciepub.com/jfnr/4/7/2/
- Description: Publisher version , Pleurotus tuber-regium (Fr.) Singer (1951) is a unique sclerotium-forming edible and medicinal mushroom. Interestingly, both the sclerotium and mushroom are edible and are often used for curing various ailments. Previous studies have focused on the antimicrobial and antioxidant activity of the extracellular polysaccharide (EPS) from wild P. tuber-regium. There has been no report on the intracellular polysaccharide (IPS) of the wild mycelia, likewise there is very meager information on the improvement of the perceived potentials of P. tuber-regium. This research study analysed the EPS and IPS fractions of P. tuber-regium hybrid and mutant strains. The antimicrobial potential of the IPS and EPS fractions, their scavenging activity on 1, 1-diphenyl–2picryhydrazyl (DPPH) and Hydroxyl radicals were also determined. Both IPS and EPS fractions of P. tuber-regium hybrids and mutants showed increased DPPH and hydroxyl scavenging activity over the wild P. tuber-regium with an EC50 mostly 1 mg/ml. The antimicrobial activity of the IPS from a mutant strain had an IC50 of 15.6 mg/ml compared to the wild type (18.75 mg /ml). This study showed that selected mutant and hybrids of P. tuber-regium had increased radical scavenging activity indicating potentially increased biological activity that could offer increased benefit as a neutraceutical.
- Full Text: false
- Date Issued: 2016
Biological control of Salvinia molesta in South Africa revisited
- Authors: Martin, Grant D , Coetzee, Julie A , Weyl, Philip S R , Parkinson, Matthew C , Hill, Martin P
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/103878 , vital:32318 , https://doi.org/10.1016/j.biocontrol.2018.06.011
- Description: The aquatic weed Salvinia molesta D.S. Mitch. (Salviniaceae) was first recorded in South Africa in the early 1900s, and by the 1960s was regarded as one of South Africa’s worst aquatic weeds. Following the release of the weevil, Cyrtobagous salviniae Calder and Sands (Coleoptera: Curculionidae) in 1985, the weed is now considered under successful biological control. However, the post-release evaluation of this biological control programme has been ad hoc, therefore, to assess the efficacy of the agent, annual quantitative surveys of South African freshwater systems have been undertaken since 2008. Over the last ten years, of the 57 S. molesta sites visited annually in South Africa, the weevil has established at all of them. Eighteen sites are under successful biological control, where the weed no longer poses a threat to the system and 19 are under substantial biological control, where biological control has reduced the impact of the weed. Since 2008, the average percentage weed cover at sites has declined significantly from 51–100% cover to 0–5% cover in 2017 (R2 = 0.78; P < 0.05). Observations of site-specific characteristics suggest that biological control is most effective at small sites and more difficult at larger and shaded sites. Our findings show that S. molesta remains under good biological control in South Africa, however, some sites require intermittent strategic management, such as augmentative releases of C. salviniae.
- Full Text:
- Date Issued: 2018
BTR SARMCOL Strike update Feb. 1986
- Authors: MAWU, COSATU
- Date: Feb 1986
- Subjects: MAWU, COSATU
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/111225 , vital:33416
- Description: CHRISTMAS Day 1985 in Howick/Mpophomeni marked the 34th week of the strike by Sarmcol workers over the recognition of trade union rights by the Company. While local white residents of HowicK planned their Christmas festivities the Sarmcol strikers still entirely dependant on the small weekly food parcels supplied by MAWU, planned to bring home to local Sanncol management their determination to secure their reinstatement at the factory and the recognition of MAWU. Accordingly on Christmas Day the strikers and their families dressed in black, took buses into the white CBD of Howick to attend the morning Christmas church service at the local Anglican Church — the church of Senior Sarmcol management. Most of the strikers were told to sit in a corner wing of the church while the others stood outside. However at Communion the white Anglicans including Mr. Sampson, the Sarmcol financial director, were joined by the Anglicans amongst the strikers. The morning service was sombre but peaceful. After the service the strikers who rwere unable to afford the transport fares decided to walk back to their homes which in terms of South Africa’s grand apartheid plans have been located over 20 kins from Howick. The march which was led by sympathetic priests from the area, was closely followed by the SA Police who waited until the strikers had gone beyond the white residential areas and then broke up the procession and forced the strikers to board buses from the nearby Merrivale bus rank. In order to keep Christmas a peaceful day the strikers did not resist and boarded the buses back to their township. In the township the strikers gathered outside the church for a brief discussion and prayer and reconfirmed their determination to continue their struggle against BTR irrespective of the cost.
- Full Text:
- Date Issued: Feb 1986
Building a firm base for policy consensus statement
- Authors: NEDLAC
- Date: 1995
- Subjects: NEDLAC
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/151641 , vital:39156
- Description: We have arrived at a very important stage in the development of our country - one that will be most testing and challenging for all of us. Our second revolution, so to speak, is only beginning. The Government of National Unity, has come a long way in addressing the key political questions. Advancement from here lies in our economic prerogative. We are all concerned with the major economic challenge that lies ahead. Sustainable economic growth, the creation of wealth and equity, the provision of jobs and basic needs underpin the need to provide mechanisms which will facilitate growth, development and delivery. But our concern is not limited to our domestic economy.
- Full Text:
- Date Issued: 1995
Business Statistics: STD 121
- Authors: Odeyemi, A , Tyler, J
- Date: 2010-11
- Language: English
- Type: Examination paper
- Identifier: vital:11976 , http://hdl.handle.net/10353/d1010341
- Description: Business Statistics: STD 121, degree exmaination November 2010.
- Full Text: false
- Date Issued: 2010-11
Can workers look forward to a safer and healthier workplace in the new South Africa
- Authors: Industrial Health Research Group
- Date: 19--?
- Subjects: Industrial safety -- Law and legislation -- South Africa , Industrial hygiene -- Law and legislation -- South Africa
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/76015 , vital:30492
- Full Text:
- Date Issued: 19--?
Ceropegia macmasteri (Apocynaceae-Asclepiadoideae-Ceropegieae), a new species from Eastern Cape, South Africa
- Authors: Dold, Anthony P
- Date: 2006
- Language: English
- Type: Article
- Identifier: vital:6515 , http://hdl.handle.net/10962/d1005943 , http://dx.doi.org/10.1016/j.sajb.2005.06.005
- Description: Ceropegia macmasteri, a new species from Cathcart in the Eastern Cape Province of South Africa, is only known from a single population in Dohne sourveld grassland where it occurs with another rare local endemic species of the Ceropegieae, Brachystelma cathcartense R.A.Dyer. The new species, an herbaceous grassland plant with a tuberous rootstock, most closely resembles C. stentiae E.A.Bruce, but is distinguished by its linear-erect corona lobes and inner corona conniving to form a central column.
- Full Text:
- Date Issued: 2006
Comfortably numb: Crump unveiled—a review of the 2011 Alan Crump retrospective exhibitio
- Authors: Cooper, Paul S
- Date: 2011
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147924 , vital:38685 , DOI:10.1080/00043389.2011.11877152
- Description: Writing can at times be difficult. It is not without considerable anxiety that I undertake to write this particular review. Perhaps I should offer a short qualifier: this is not strictly a review but rather a collection of ideas around the works and their arrangement, as well as my own musings and reflections on Crump. I want to pick up on what I identify to be an approach that personalises Crump as a professor, colleague and artist (we find this tone embedded throughout the accompanying exhibition catalogue). 1 I have chosen to structure this essay using a series of trigger headings, some provocative and possibly even inflammatory, others more neutral and concerned with getting to the core of what this retrospective and posthumous show is all about. All the while my thinking is to channel a sense (or lack thereof, as it may turn out) of my own experience of his work and person.
- Full Text:
- Date Issued: 2011
Comparative blanching activities of proprietary diflucortolone valerate topical preparations
- Authors: Coleman, Gerald L , Kanfer, Isadore , Haigh, John M
- Date: 1978
- Language: English
- Type: Article
- Identifier: vital:6350 , http://hdl.handle.net/10962/d1006032
- Description: The blanching activities and hence bioavailabilities of the cream, ointment and fatty ointment preparations of Nerisone and Temetex (diflucortolone valerate 0.1%) were evaluated using an occluded and unoccluded blanching assay. These products were compared to Synalar ointment and cream (fluocinolone acetonide 0.025%), established topical corticosteroid preparations. Statistical analysis showed no significant differences between similar formulations of diflucortolone valerate. Significant differences were noted between diflucortolone valerate and fluocinolone acetonide preparations.
- Full Text:
- Date Issued: 1978
Compounds isolation and biological activities of Piptadeniastrum africanum (hook. f.) Brennan (Fabaceae) roots:
- Authors: Teinkela, Jean E M , Noundou, Xavier S , Mimba, Jeanne E Z , Meyer, Franck , Tabouguia, Octavie M , Nguedia, Jules C A , Hoppe, Heinrich C , Krause, Rui W M , Wintjens, René , Azebaze, Anatole G B
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150084 , vital:38938 , https://doi.org/10.1016/j.jep.2020.112716
- Description: The dicotyledonous plant Piptadeniastrum africanum (hook.f.) Brennan (Fabaceae) is used in traditional medicine to treat various human complaints including bronchitis, coughing, urino-genital ailments, meningitis, abdominal pain, treatment of wounds, malaria and gastrointestinal ailments, and is used as a purgative and worm expeller. The present study describes the phytochemical investigation and the determination of the antimicrobial, antiplasmodial and antitrypanosomal activities of crude extract, fractions and compounds extracted from Piptadeniastrum africanum roots.
- Full Text:
- Date Issued: 2020
Congruence between fine-scale genetic breaks and dispersal potential in an estuarine seaweed across multiple transition zones:
- Authors: Nicastro, Katy R , Assis, Jorge , Serrão, Ester A , Pearson, Gareth A , Neiva, Joao , Valero, Myriam , Jacinto, Rita , Zardi, Gerardo I
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149873 , vital:38908 , https://0-doi.org.wam.seals.ac.za/10.1093/icesjms/fsz179
- Description: Genetic structure in biogeographical transition zones can be shaped by several factors including limited dispersal across barriers, admixture following secondary contact, differential selection, and mating incompatibility. A striking example is found in Northwest France and Northwest Spain, where the estuarine seaweed Fucus ceranoides L. exhibits sharp, regional genetic clustering. This pattern has been related to historical population fragmentation and divergence into distinct glacial refugia, followed by post-glacial expansion and secondary contact. The contemporary persistence of sharp ancient genetic breaks between nearby estuaries has been attributed to prior colonization effects (density barriers) but the effect of oceanographic barriers has not been tested. Here, through a combination of mesoscale sampling (15 consecutive populations) and population genetic data (mtIGS) in NW France, we define regional genetic disjunctions similar to those described in NW Iberia. Most importantly, using high resolution dispersal simulations for Brittany and Iberian populations, we provide evidence for a central role of contemporary hydrodynamics in maintaining genetic breaks across these two major biogeographic transition zones. Our findings further show the importance of a comprehensive understanding of oceanographic regimes in hydrodynamically complex coastal regions to explain the maintenance of sharp genetic breaks along continuously populated coastlines.
- Full Text:
- Date Issued: 2020
Conspecific alarm cue sensitivity by the estuarine calanoid copepod, Paracartia longipatella
- Authors: Wasserman, Ryan J , Kramer, Rachel , Vink, Tim J F , Froneman, P William
- Date: 2014
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/68062 , vital:29194 , https://doi.org/10.1111/aec.12135
- Description: Publisher version , Sensitivity to chemical cues associated with predation threat has been well observed in many freshwater zooplankters, yet few studies have highlighted such sensitivity in eury- and stenohaline metazoans. We aimed to assess sensitivity to conspecific chemical alarm cues in the estuarine copepod, Paracartia longipatella. Alarm cues associated with predation have been shown to have population level effects on certain zooplanktonic species. As such, we assessed the occurrence of such effects on population dynamics of P.longipatella over a 12 day period. Using experimental in situ mesocosms, we compared P.longipatella adult, copepodite and nauplii numbers between three treatments; one inoculated with conspecific alarm cues, one containing direct predation pressure (zooplanktivorous fish), and a control treatment containing no predation threat. Trends in population abundances were similar between the direct predation and alarm cue treatments for the six days of the experiment, decreasing in abundance. During the latter half of the study, however, P.longipatella abundances in the alarm cue treatment increased, while those in the presence of direct predation continued to decrease. In the treatment absent of any predation threat, P.longipatella abundances increased consistently over time for the duration of the study. We suggest that P.longipatella are indeed sensitive to conspecific alarm cues associated with predation threat. Furthermore, we propose that prolonged exposure to conspecific alarm cues in the absence of any real threat results in a reduction in sensitive to these cues.
- Full Text: false
- Date Issued: 2014