Book chapter 6 - Sena.pdf
- Authors: Oyedeji, Adebola Omowunmi
- Language: English
- Identifier: http://hdl.handle.net/11260/2500 , vital:41893
- Description: Various articles from Prof Adebola Oyedeji
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Cardiometabolic risk factors and early indicators of vascular dysfunction: a cross-sectional cohort study in South African adolescents
- Authors: Letswalo, Boitumelo Prescilla , Schmid-Zalaudek, Karin , Brix, Bianca , Matjuda, Edna Ngoakoana , Klosz, Fabian , Obernhumer, Natalie , Gaisl, Michael , Engwa, Godwill Azeh , Sewani-Rusike, Constance , Fredriksen, Per Morten , Nkeh-Chungag, Benedicta , Goswami, Nandu
- Date: 2021
- Language: English
- Type: Journal article
- Identifier: http://hdl.handle.net/11260/3864 , vital:43959
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Causes of conflict in school governing bodies of Mthatha district schools in King Sabata Dalindyebo Municipality
- Authors: Mandisa Nokwanda Memela
- Date: 2013
- Language: English
- Type: Masters
- Identifier: http://hdl.handle.net/11260/2838 , vital:42963
- Description: ABSTRACT According to the South African Schools Act (Act 84, 1996) (SASA), which came into effect in the beginning of 1997, all public schools in South Africa should have democratically elected School Governing Bodies, with parents, educators, non-teaching staff, learners and the principal. Their functions included creating an environment conducive to teaching and learning, developing a vision and mission statement for the school and promoting the best interests of the school. School governance practices are performed with tension due to values inherent in African traditions; customs and values of modern school leadership. Integrating schools and the communities and making the former accountable to its community and having representations of legitimate interests in the schools are seen as politically and socially correct. It is argued that conflicts and tensions in school governance are likely to continue. In this study, the researcher explores and analyses causes of conflict in SGBs of Mthatha District schools in King Sabata Dalindyebo Municipality. A quantitative study using questionnaires was conducted, using five respondents of the School Governing Bodies (SGBs) from each of the rural, semi-urban and urban schools. Two schools were selected from each of these categories. This gave a total of thirty respondents. Non- probability purposive sampling was used. Two types of comparative analysis were done to the quantitative data. There was the usual descriptive statistical analysis meant to draw comparisons based on the responses within a given variable. This was the initial analysis for quantitative data. Some reliable conclusions were determined from this analysis. The findings of the study reveal numerous causes of conflict in SGBs related to SGB‟s in ability to execute their functions and ability to rule the school as prescribed in the South Africa Schools Act.84 of 1996. The causes of conflict include parents‟ level of education, parental interference, illiteracy, or lack of transparency, recruitment and lack of financial mismanagement. Finally, it is also evident that only learners could not be blamed for causing conflict. The study concludes with some recommendations, amongst them that there should be a friendly atmosphere between parents and teachers with teachers accepting the presence and involvement of parents in the running of school activities but that parents should not interfere in the teaching practices of educators and should not be at school during odd hours of the day.
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Centella asiatica.pdf
- Authors: Oyedeji, Adebola Omowunmi
- Language: English
- Identifier: http://hdl.handle.net/11260/2487 , vital:41908
- Description: Various articles from Prof Adebola Oyedeji
- Full Text: false
Change in renal function post-nephrectomy for renal cell carcinoma in patients with and without hypertension and/or diabetes
- Authors: John, J , Henry, M , Ringoir, A , Pinto, G , Kesner, K , Lazarus, J , Sinha, S
- Date: 2020
- Subjects: RCC, Nephrectomy, eGFR, CKD
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/6368 , vital:45380
- Description: BACKGROUND: The standard of care for surgically resectable disease renal cell carcinoma (RCC) is a nephrectomy. Post nephrectomy, these patients are at risk for the development of new onset chronic kidney disease or the progression of pre-existing chronic kidney disease. We aimed to report the changes in renal function in patients who had a nephrectomy for RCC METHODS: This retrospective, descriptive, cross-sectional study identified 137 patients who had a nephrectomy for RCC from 1 January 2009 to 31 December 2017. The pre-nephrectomy and post-nephrectomy estimated glomerular filtration rate (eGFR) and the histological subtype of RCC on histopathological analysis of the resected specimen were recorded from the National Health Laboratory Services online results platform. All analyses were conducted using SPSS (Version 25) and the significance level was set at p < 0.05 RESULTS: After a mean follow-up period of 26.5 ± 22 months (median = 19 months), the patients' eGFR dropped by a mean of 4.82 ± 8.67 ml/min/1.73 m2 (95% CI 3.23-6.41) post-nephrectomy. The mean eGFR fall in patients' who had hypertension and/or diabetes (n = 63) was significantly larger compared to patients who had neither of these comorbidities (n = 54; p < .001; mean = 7.30 ± 8.40 ml/min/1.73 m2 (95% CI 5.19-9.42) and 1.93 ± 8.14 ml/min/1.73 m2 (95% CI 0.30-4.15) respectively CONCLUSIONS: The decline in renal function in patients with hypertension and/or diabetes mellitus is more pronounced than in patients with neither of these comorbidities. In these high-risk patients, measures must be taken to prevent the development and limit the progression of chronic kidney disease
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Clinical and demographic profile of catatonic patients who received electroconvulsive therapy in a South African setting
- Authors: Kavendren Odayar , Ingrid Elof , Willem Esterhuysen
- Date: 2018
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4719 , vital:44168
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Comparison of the Therapeutic Effectiveness of Abacavir and Stavudine as part of the First Line Antiretroviral Therapy Nucleoside Reverse Transcriptase Backbone for Children in East London, South Africa
- Authors: Cheree Ann Goldswain
- Date: 2016
- Subjects: Paediatrics, Medicine
- Language: English
- Type: Thesis, Masters
- Identifier: http://hdl.handle.net/11260/2137 , vital:40902
- Full Text: false
Comprehensive data on the mechanical properties and biodegradation profile of polylactide composites developed for hard tissue repairs
- Authors: Abraham K. Aworinde , Samson O. Adeosun , Festus A. Oyawale , Eyere Emagbetere , Felix A. Ishola , Obafemi Olatunji , Stephen A. Akinlab , Sunday O. Oyedepo , Oluseyi O. Ajayi , Esther T. Akinlabi
- Date: 2020
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4152 , vital:44032
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Conditional economic incentives to improve HIV prevention
- Authors: Mark K U Pasayan , Adeyinka A Alab , Douglas F Nixon
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4723 , vital:44169
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Corrigendum to “Perinatal maternal depression in rural South Africa: Child outcomes over the first two years”. Journal of Affective Disorders, 247 (2019) 168-174
- Authors: Joan Christodoulou , Karl Le Roux , Mark Tomlinson , Ingrid M. Le Roux , Linnea Stansert Katzen , Mary Jane Rotheram-Borus
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4136 , vital:44029
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Cross-sectional study of diabetes kidney disease in the Eastern Cape, South Africa
- Authors: Oladele Vincent Adeniyi , Eyitayo Omolara Owolabi
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4569 , vital:44134
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Cross-sectional study of diabetes kidney disease in the Eastern Cape, South Africa
- Authors: Oladele Vincent Adeniyi , Eyitayo Omolara Owolabi
- Date: 2020
- Language: English
- Type: Journal article
- Identifier: http://hdl.handle.net/11260/3856 , vital:43958
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Data on microhardness and structural analysis of friction stir spot welded lap joints of AA5083-H116
- Authors: Esther T. Akinlabi , Ayuba S. Osinubi , Nkosinathi Madushele , Stephen A. Akinlabi , Omolayo M. Ikumapayi
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4168 , vital:44034
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Data on microhardness and structural analysis of friction stir spot welded lap joints of AA5083-H116
- Authors: Esther T. Akinlabi , Ayuba S. Osinubi , Nkosinathi Madushele , Stephen A. Akinlabi , M. Ikumapayi
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/3801 , vital:43949
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Dataset and ANN model prediction of performance of graphene nanolubricant with R600a in domestic refrigerator system
- Authors: T.O. Babarinde a , S.A. Akinlabi , D.M. Madyira , F.M. Ekundayo , P.A. Adedeji
- Date: 2020
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4144 , vital:44030
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Decreased total antioxidant levels and increased oxidative stress in South African type 2 diabetes mellitus patients
- Authors: FA Ganjifrockwala , JT Joseph , G George
- Date: 2017
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/3686 , vital:43925
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Detection of a SARS-CoV-2 variant of concern in South Africa
- Authors: Oluwakemi Laguda-Akingba
- Date: 2021
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4505 , vital:44127
- Description: Continued uncontrolled transmission of SARS-CoV-2 in many parts of the world is creating conditions for substantial evolutionary changes to the virus1,2. Here we describe a newly arisen lineage of SARS-CoV-2 (designated 501Y.V2; also known as B.1.351 or 20H) that is defined by eight mutations in the spike protein, including three substitutions (K417N, E484K and N501Y) at residues in its receptor-binding domain that may have functional importance3–5. This lineage was identified in South Africa after the first wave of the epidemic in a severely affected metropolitan area (Nelson Mandela Bay) that is located on the coast of the Eastern Cape province. This lineage spread rapidly, and became dominant in Eastern Cape, Western Cape and KwaZulu– Natal provinces within weeks. Although the full import of the mutations is yet to be determined, the genomic data—which show rapid expansion and displacement of other lineages in several regions—suggest that this lineage is associated with a selection advantage that most plausibly results from increased transmissibility or immune escape6–8.
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Detection of extended spectrum beta‑lactamase genes in Pseudomonas aeruginosa isolated from patients in rural Eastern Cape Province, South Africa
- Authors: Mojisola C. Hosu , Sandeep D. Vasaikar, , Grace E. Okuthe , Teke Apalata
- Date: 2021
- Language: English
- Type: Journal Article
- Identifier: http://hdl.handle.net/11260/4509 , vital:44128
- Description: The proliferation of extended spectrum beta-lactamase (ESBL) producing Pseudomonas aeruginosa represent a major public health threat. In this study, we evaluated the antimicrobial resistance patterns of P. aeruginosa strains and characterized the ESBLs and Metallo- β-lactamases (MBL) produced. Strains of P. aeruginosa cultured from patients who attended Nelson Mandela Academic Hospital and other clinics in the four district municipalities of the Eastern Cape between August 2017 and May 2019 were identified; antimicrobial susceptibility testing was carried out against thirteen clinically relevant antibiotics using the BioMérieux VITEK 2 and confirmed by Beckman autoSCAN-4 System. Real-time PCR was done using Roche Light Cycler 2.0 to detect the presence of ESBLs; blaSHV, blaTEM and blaCTX-M genes; and MBLs; blaIMP, blaVIM. Strains of P. aeruginosa demonstrated resistance to wide-ranging clinically relevant antibiotics including piperacillin (64.2%), followed by aztreonam (57.8%), cefepime (51.5%), ceftazidime (51.0%), piperacillin/tazobactam (50.5%), and imipenem (46.6%). A total of 75 (36.8%) multidrug-resistant (MDR) strains were observed of the total pool of isolates. The blaTEM, blaSHV and blaCTX-M was detected in 79.3%, 69.5% and 31.7% isolates (n = 82), respectively. The blaIMP was detected in 1.25% while no blaVIM was detected in any of the strains tested. The study showed a high rate of MDR P. aeruginosa in our setting. The vast majority of these resistant strains carried blaTEM and blaSHV genes. Continuous monitoring of antimicrobial resistance and strict compliance towards infection prevention and control practices are the best defence against spread of MDR P. aeruginosa.
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Detection of sexually transmitted pathogens and co-infection with human papillomavirus in women residing in rural Eastern Cape, South Africa
- Authors: Taku, Ongeziwe , Brink, Adrian , Meiring, Tracy L , Phohlo, Keletso , Businge, Charles B , Mbulawa, Zizipho Z A , Williamson, Anna-Lise
- Date: 2021
- Language: English
- Type: Journal article
- Identifier: http://hdl.handle.net/11260/4064 , vital:44019
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Determinants of type 2 Diabetes mellitus among HIV/AIDS patients on antiretroviral drugs in the OR Tambo District, SA
- Authors: Nokwanda Edith Bam
- Date: 2018
- Language: English
- Type: PhD Manuscript
- Identifier: http://hdl.handle.net/11260/2073 , vital:40815
- Description: Background: Type 2 Diabetes mellitus (DM) is increasing in the context of HIV/AIDS as a result of the long-term effects of ARVS. Little is documented in South Africa on the determinants of type 2 DM in HIV/AIDS population although the prevalence is high (Moyo, et al., 2014). The purpose of this study was to describe the determinants of type 2 diabetes mellitus among HIV/AIDS patients on ARVS in the OR Tambo District. Methods: A quantitative research methodology using a case control retrospective study was used to describe the determinants of type 2 DM among HIV/AIDS patients in OR Tambo District. A sample of 177 (33%) cases with HIV/AIDS and type 2 DM was selected using a one stage stratified sampling with allocation proportion to size of each stratum of the four sub-districts of OR Tambo District. For example KSD 80 cases, Nyandeni 43; Qaukeni 36 and Mhlontlo 18. Two non-diabetic patients with HIV/AIDS were selected as controls per case unpaired and totalled up to 354 (67%) controls. A self - administration questionnaire adopted from WHO stepwise surveillance tool was used for data collection. Results: Findings of the study revealed five determinants of type 2 diabetes mellitus grouped as the socio-demographic determinants, levels of physical activities, types of diets, arterial blood pressure and body weight and types of combination antiretroviral therapies used in HIV/AIDS therapy. In addition the association of type 2 DM with HIV was shown to include ARV complications, number of years on ARVS and the tri-therapy versus fixed dose combination. Conclusion: Type 2 DM is a major complication of ARVS experienced by the cases at n=108 (61%) compared to others such as lipodystrophy n=10 (5.6%), skin disorders n=7 (3.9%) and bad dreams n=2 (1%). Consequently a multi-morbidity situation co-exists among the cases creating as shift from as single disease to a multiple-disease focus namely ARVS, anti-DM, anti-HPT etc. Recommendations on the HIV/AIDS and type 2 DM awareness and care intervention strategy were made to improve the health outcomes of type 2 DM patients in HIV/AIDS context in OR Tambo District.
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