The Trope of the Child: Rereading Trauma, Subjectivity and Embodiment in Contemporary Child-Centred African Narratives by Ahmadou Kourouma, Chris Abani, K. Sello Duiker and Yvonne Vera
- Authors: Njovane, Thandokazi
- Date: 2019
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/164557 , vital:41134 , doi:10.21504/10962/164557
- Description: Thesis (PhD)--Rhodes University, Humanities, Literary Studies in English, 2019
- Full Text:
- Date Issued: 2019
The silent patient: a consideration of Gendlin's recommendations in the treatment of a silent adolescent
- Authors: Le Roux, J D
- Date: 1990
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/193054 , vital:45294
- Description: This study comprises a dialogue between Gendlin's recommendations on the treatment of the silent patient and case-material taken from 39 sessions of psychodynamic psychotherapy with a 16 year old adolescent. The most characteristic feature of the therapy with this young person, was her pattern of silence and unresponsiveness. The aim of this study is to ascertain the usefulness of Gendlin's recommendations in the therapy of this category of patient. The dialogue between the suggested recommendations and the case- material served to illustrate the point that Gendlin's recommendations are of great value in the treatment of the silent adolescent. The value of these recommendations lie in their ability to comment meaningfully on the process of therapy with the silent patient by providing not only skills and techniques, but also a conceptual framework within which to contextualize the therapy. The recommendations were also found to be sensitive to some of the key issues of relevance to adolescence as a developmental phase. The case-study method was deemed an appropriate structure within which to conduct this examination. , Thesis (MA) -- Faculty of Humanities, Psychology, 1990
- Full Text:
- Date Issued: 1990
The search for daily meaning: A technique for career counselling
- Authors: Rainier, Markseller Garrett
- Date: 1994
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/193003 , vital:45289
- Description: Because work is such a tremendous potential source of meaning in an individual’s life, techniques which turn career choice into technical talent matching are inadequate. The individual’s search for authentic meaning needs to be the focus of career counselling, but few approaches have been able to addressed this relationship between working and living. Major developments in career theory are reviewed to highlight the distinction between the more technical logical positivist and the phenomenological approaches. Super’s Career- Development Assessment and Counselling (C-DAC) model is described in detail as it is the first significant attempt to move beyond the technical approaches by incorporating developmental theory into career counselling and by stressing the role of counsellee readiness to use the information provided. However, especially in South Africa, any test-based approach to career counselling runs the risk of shifting the locus of control from the counsellee to the counsellor, so an autobiographical non-test approach, the life-line, is introduced to assist counsellees in their search for personal meaning without running the risks associated with test-based assessments. The life-line helps to contextualise the choice of work within the counsellee’s subjective life experience and turns career counselling into a shared search for a range of personal meanings rather than the provision, by the counsellor, of a limiting interpretation. Three case studies are presented to demonstrate the use of the life-line, and the conclusions arrived at are shown to be essentially1 similar to conclusions obtained from using the C-DAC battery. The advantages and limitations of the life-line are discussed and its ability to combat problems associated with school based career counselling is outlined as well as its usefulness with mid-life career changers, in cross-cultural contexts, and in group counselling. , Thesis (MA) -- Faculty of Humanities, Psychology, 1990
- Full Text:
- Date Issued: 1994
The role of the Hop co-chaperone in the formation of Hsp90 complexes: chaperone link to glycolysis
- Authors: Maharaj, Shantal
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/163593 , vital:41051 , doi:10.21504/10962/163593
- Description: Thesis (PhD)--Rhodes University, Faculty of Science, Biochemistry and Microbiology, 2020
- Full Text:
- Date Issued: 2020
The Role of the courts in the interpretation and implementation of the Right to Basic Education in Section 29(1)(a) of the South African Constitution
- Authors: Ngubane, Kwanele Nhlanhla
- Date: 2023-10-13
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/424141 , vital:72127
- Description: The right to education in section 29(1)(a) of the Constitution was meant to signal a break between an education system divided along racial lines, and a new democratic education system based on equity, equality, and opportunity for all learners. In reality, the South African education system still remains deeply divided along racial lines, with poor, mostly black learners, being under-resourced by the state, while their richer, mostly white, counterparts are being taught in schools that have access to all the resources necessary to realise the right to basic education. As a result, the right to education in section 29(1)(a) of the Constitution has been heavily debated, and between 2010 and 2022, the South African courts have often been called on to interpret the right. In the process, a rich jurisprudence has developed on the core content of the right to basic education, with findings by the courts that the right includes an entitlement to a number of educational resources. These include access to school infrastructure, learner-teacher support materials, desks and chairs, scholar transport, teaching and non-teaching staff, and nutrition. This study examines the way South African courts, between 2010 and 2022, have interpreted and implemented the right to basic education to give effect to section 29(1)(a) of the Constitution. While South African courts have historically shied away from interpreting socio-economic rights to contain a minimum core content and have rather opted for a reasonableness approach, the same is not entirely true for section 29(1)(a). As stated above, courts have been willing to find that the right entails a minimum basket of goods and services without which the right cannot be realised. By examining some of the most important education rights cases during this period, the study proposes that there are five factors that have guided the courts’ interpretation of the right and has assisted in the courts finding that the right contains a minimum core content. These factors are the historical context of the right to basic education; the textual formulation of the right to basic education in section 29(1)(a) of the Constitution; the interrelatedness of the right to basic education and other rights within the Bill of Rights; subsidiary education policies, legislation, and regulations, and lastly, the role of international law. This study seeks to consider the extent to which each of these factors have played a role in courts’ interpretation of section 29(1)(a). The study also considers the implementation of these judgments and the role that the courts have played in realising the right to education for learners on ground-level. , Thesis (LLM) -- Faculty of Law, Law, 2023
- Full Text:
- Date Issued: 2023-10-13
The role of optimism bias in susceptibility to phishing attacks in a financial services organisation
- Authors: Owen, Morné
- Date: 2023-03-31
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/419257 , vital:71629 , DOI 10.21504/10962/419257
- Description: Researchers looking for ways to change the insecure behaviour that results in successful phishing have considered multiple possible reasons for such behaviour. Therefore, the purpose of this study is to understand the role of optimism bias (OB – defined as a cognitive bias), which characterises overly optimistic or unrealistic individuals, in order to ensure secure behaviour. Research is considered that has focused on issues such as personality traits, trust, attitude and information security awareness training (ISAT). We used a mixed methods design to investigate OB behaviour, building on a recontextualised version of the theory of planned behaviour to evaluate the influence that OB has on phishing susceptibility. To model the data, an analysis was performed on 226 survey responses (systematic random sampling method) from the employees of a financial services organisation using partial least squares (PLS) path modelling. To evaluate OB behaviour, we conducted an experiment consisting of three ISAT sessions and three simulated phishing attacks. After each phishing experiment, we conducted interviews to gain a better understanding of why people succumbed to the attacks. It was subsequently found that overly optimistic individuals are inclined to behave insecurely, while factors such as attitude and trust significantly influence the intention to behave securely. Our contribution to practice is to enhance the effectiveness of ISAT by identifying and addressing the OB weakness to deliver a more successful training outcome. Our contribution to theory enriches the Information Systems literature by evaluating the effect of a cognitive bias on phishing susceptibility and, through research, offering a contextual explanation of the resultant behaviour. , Thesis (PhD) -- Faculty of Commerce, Information Systems, 2023 , Navorsers op soek na ‘n antwoord om onveilige gedrag te verander wat lei na uitvissing het verskeie moontlike redes oorweeg vir sulke gedrag. Daarom is die doel van hierdie verhandeling om die rol van optimistiese vooroordeel (OB - gedefinieer as 'n kognitiewe vooroordeel) te verstaan, wat te optimistiese of onrealistiese individue kenmerk om veilige gedrag te verseker. Navorsing was oorweeg wat gefokus het op kwessies soos persoonlikheidseienskappe, vertroue, gesindheid en inligtingsekuriteitsbewustheidsopleiding (ISAT). Die navorser het gemengde metodes gebruik om OB-gedrag te ondersoek. Daar was voortgebou op 'n gerekontekstualiseerde weergawe van die theory of planned behaviour om die invloed wat OB op uitvissing-vatbaarheid het, te evalueer. Om die data te modelleer, is 'n analise gedoen waar 226 opname antwoorde verkry is van 'n finansiële dienste organisasie en is partial least squares (PLS) path modelling gebruik. Om OB-gedrag te evalueer, het ons 'n eksperiment uitgevoer wat bestaan uit drie ISAT-sessies en drie gesimuleerde uitvissing-aanvalle. Na elke uitvissing-eksperiment het ons onderhoude gevoer om 'n beter begrip te kry waarom mense aan die aanvalle geswig het. Te optimistiese individue is geneig om onveilig op te tree, terwyl faktore soos gesindheid en vertroue die voorneme om veilig op te tree, aansienlik beïnvloed het. Die studie se bydrae tot die praktyk is om die doeltreffendheid van ISAT te verbeter deur die OBswakheid te identifiseer en aan te spreek om 'n meer suksesvolle opleidingsuitkoms te lewer. Verder verryk die studie die Inligtingstelsels-literatuur deur die effek van 'n kognitiewe vooroordeel op uitvissing-vatbaarheid te evalueer en deur navorsing bied dit 'n kontekstuele verduideliking van die gevolglike gedrag.
- Full Text:
- Date Issued: 2023-03-31
The Role of HSP70/HSP90 Organizing Protein (Hop) in the Heat Shock Factor 1 (HSF1)-mediated Stress Response
- Authors: Chakraborty, Abantika
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/163204 , vital:41018 , doi:10.21504/10962/163204
- Description: Molecular chaperones regulate cellular proteostasis. They control protein conformation and prevent misfolding and aggregation under both normal and stressful environments, ultimately resulting in cell survival. The project aimed to understand the role of the HSP70 – HSP90 Organizing Protein (Hop/STIP1) in the survival of stressed cells and the function of the stress-responsive transcription factor, Heat Shock Factor 1 (HSF1). HSF1 protein levels were significantly reduced in Hop-depleted HEK293T cells compared to controls by ELISA, western blot, and mass spectrometry. HSF1 transcriptional activity at the HSP70 promoter, and binding of a biotinylated HSE oligonucleotide under basal conditions were significantly reduced, consistent with the reduced levels of HSF1. In response to heat shock, HSF1 levels in Hop-depleted cells increased to that of controls, but there was still significantly lowerHSF1 transcriptional activity and HSE binding. Hop-depleted HEK293T cells were more sensitive than controls to the HSF1 inhibitor KRIBB11 and showed reduced short-term and long-term proliferation. Unlike the HSP90 inhibitor 17-DMAG, which had no effect, the HSP70 inhibitor JG98, further decreased the levels of HSF1 in Hop-depleted cells, suggesting a role for HSP70 in the Hop-mediated effects. There was punctate nuclear staining for HSF1 in Hop-depleted cells under both basal and heat shock conditions, as well as reduced nuclear localization and increased cytoplasmic accumulation of HSF1 in response to heat shock. Hop and HSF1 colocalized in cells, and HSF1 could be isolated in complex with Hop and HSP70. Loss of Hop reduced HSF1 in HSP70complexes but did not affect HSF1 abundance in HSP90 complexes. Hop-depleted cells showed reduced short-term and long-term survival compared to controls, an effect that was potentiated by the JG98 HSP70 inhibitor. Taken together, these data suggest that Hop regulation of HSF1activity is via a mechanism involving reductions in HSP70 interaction, as well as reduced nuclear localization, and DNA binding, and is consistent with reduced cellular fitness under basal and stress conditions. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2020
- Full Text:
- Date Issued: 2020
The relevance of sustainable development principles and goals through a case study of Gold Fields and Living Gold
- Authors: Ferreira, Adrian
- Date: 2007
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192977 , vital:45286
- Description: The conventional definition of sustainable development as proposed by the Brundtland Report (United Nations, 1987), involving the integration of economic, social and environmental components, is widely accepted. Presumed benefits of these current framework applications tend to perpetuate a business as usual status, with no real sustainable development occurring. The growing debate surrounding this topic makes the case for relevant and contextual inputs to be included into sustainable development objectives. A case study, of Gold Fields and Living Gold, attempts to create a deeper understanding of the components of this debate, and begins to contextualise sustainable development principles, goals and their outcomes. This is carried out though an enquiry of the use of cultural development as a fourth sustainable development category. The case study includes the opinions of a directly affected local community entity (Living Gold) in order to observe the difference between the two organisations (Gold Fields and Living Gold). During the study, the focus began to move away from purely unabated growth impacts and looked to the creation and fostering of resilience and flexibility by the use of adaptive management. In breeding states of resilience, it was recognised that cultural impacts played an important role in ensuring long term systemic resilience. The case study involved assessing the feedback and responses of strategically selected individuals at both organisations, with Gold Fields representing a more western centric entity and Living Gold a formal representation of a traditional/ indigenous community. Similarities and differences were assessed in order to understand how current sustainable development criteria might differ between organisations that have different end objectives in mind, yet are dependent on each other. The findings resulted in a perspective of how culture could be used to describe the qualities of a local community, and how to begin aligning development goals with affected communities. The result was the development of the Integrated Resilience Sustainability Method and the consequent development of the Balanced Bottom Line Framework, which seeks to promote sustainable development along the lines of economic, social, environmental and cultural development. , Thesis (MBA) -- Faculty of Commerce, Rhodes Investec Business School, 2007
- Full Text:
- Date Issued: 2007
The relative suitability of knowledge paradigms to indigenous African resource management and their implications for environmental bioethics, environmental policy and food security
- Authors: Agbor Ambang, Oscar Mbi
- Date: 2020-04
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , M.Pharm
- Identifier: http://hdl.handle.net/10962/163091 , vital:41011
- Description: Thesis (M.Pharm)--Rhodes University, Faculty of Pharmacy, Pharmacy, 2020.
- Full Text:
- Date Issued: 2020-04
The regeneration of palmiet (prionium serratum) following hydrogeomorphic disturbance: a case study of the Kromme River wetland
- Authors: Van Eck, Caydon Daniël
- Date: 2022-10-14
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/365555 , vital:65759
- Description: The Kromme River wetland in the Eastern Cape of South Africa occupies a broad valley (up to 350 m wide) with a gentle longitudinal slope of less than 2 % that has been formed by cut-and-fill cycles that are initiated by trunk-tributary interactions. These hydrogeomorphic disturbance events trigger gully erosion and generate sediments, the coarse fraction of which is deposited less than 2 km downstream, leading to depositional floodout features that fill gullies headwards. This process has been occurring at intervals for at least 10 000 years, and as such pre-dates the introduction of European farming practices in the area. Plants that regenerate by colonising these features are thought to have evolved adaptions necessary to colonise intermittently produced bare sandy sediments. This study aimed to examine the regeneration ecology of palmiet (Prionium serratum), the dominant vegetation community within these cut-and-fill wetlands, by relating its regeneration characteristics to environmental factors in a reach of the Kromme River wetland that has experienced a recent hydrogeomorphic disturbance event (approximately 10 years before the commencement of this study). Palmiet was found to be regenerating on sedimentary deposits on beds of gullies and on depositional bars on the margins of gully beds. The large depositional floodout downstream of a large gully also favoured palmiet regeneration, where it was found to be regenerating along not only the active channel, but also along old abandoned flow paths and sometimes areas well elevated above the channel. The geomorphic features that favoured palmiet regeneration were characterised by coarse-grained sediments (mean particle size approximately 310 μm) with low organic matter content (0.61 %), a low depth to the water table and low elevation above the thalweg (mean depth to water table is approximately 0.6 m), and a relatively close distance to the thalweg (< 10 m). This understanding of palmiet’s regeneration characteristics was viewed in relation to existing literature on undisturbed palmiet wetland plant communities and its reported contribution to conditions that favour wetland formation through gully filling, which allowed for the creation of a conceptual model of palmiet regeneration, colonisation and long-term persistence. This model was based on the Fluvial Biogeomorphic Succession concept. It suggests that palmiet’s interaction with the hydrogeomorphic environment throughout the different stages of its life cycle results in self-organising biogeomorphic landforms. Over hundreds of years, the reciprocal interactions between palmiet, sediments and water, fills gullies and restores valley bottoms, ultimately leading to the formation of a wetland landform. It is further proposed that through continued accretion, the geomorphic wetland landscape becomes more and more disconnected from the hydrogeomorphic dynamics of the fluvial system, such that the prevailing conditions begin to favour fynbos establishment, which may outcompete palmiet. , Thesis (MSc) -- Faculty of Science, Geography, 2022
- Full Text:
- Date Issued: 2022-10-14
The reform of world order?: BRICS in an Interpolar world
- Authors: Phyllis, Yvonne
- Date: 2015
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/193520 , vital:45339
- Description: International relations has recently seen new developments which are unpredictable and in their infant stage. The causes of these developments are plentiful, the consequences stemming from waning unipolarity to the emergence of new fora creating their own spaces. Whatever the case, international relations is not as it was in the period just after the Cold War. As a result, the terms of global governance established after 1990 have come under serious scrutiny. This transition has the makings of a new world order, an interpolar world order. This study asserts that we no longer live in a unipolar world, nor do we live in a world which can only be described as multipolar. It makes the argument that although multipolarity is a crucial element of the world, it only offers a partial description of today’s order. The study asserts that it is interpolarity which is closest in accounting for today’s world. Not only does it describe the world as multipolar, it also describes it as interdependent. To this end, the study provides a detailed account of what is meant by an interpolar world order and how differently it explains international events. It also provides an account of factors which can develop in an interpolar world. One of these includes allowing room for emerging powers to create their own spaces in efforts of avoiding co-option while continuing to realise the importance of operating within a context of continuity. This means that emerging countries create their own spaces but they also realise the importance of working with already established regimes such as the G20. BRICS (Brazil, Russia, India, China and South Africa) is used as a case study to indicate one of the new developments afforded by an interpolar order-the emergence of new fora. The study asserts that although BRICS is rife with internal dissimilarities, it has indicated some degree of political will in one aspect; that is; advocating for the reform of the terms of global governance, advocating for more representative forms of global governance. The study thus explores factors of a world whose contours are gradually changing but which are unpredictable and in flux. , Thesis (MA) -- Faculty of Humanities, Political and International Studies, 2015
- Full Text:
- Date Issued: 2015
The proprietary consequences of foreign marriages for the purposes of estate planning and succession in South Africa
- Authors: Thorne, Aimee Liza
- Date: 2023-03-29
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/420725 , vital:71773
- Description: This thesis is intended to provide clarity regarding the proprietary consequences of foreign marriages in the context of estate planning and succession in South Africa. It includes an exploration into the impact of specific legislation on foreign marriages, the implications of matrimonial property regimes on a deceased estate in South Africa, private international law principles affecting matrimonial property and succession claims, the scope of antenuptial contracts and postnuptial contracts as existing remedies for foreign remedies, and the harmonisation of succession and matrimonial property law in the European Union (EU). It furthermore suggests potential reforms for the overhaul of the lex domicilii matrimonii principle and associated issues arising therefrom. Various specific issues discussed include the waiver of accrual claims, maintenance claims by surviving spouses of a foreign marriage, choice-of-law rules for matrimonial property rights and succession rights, the registration of a domestic or foreign antenuptial contract for foreign marriages, the formal validity and proper law of antenuptial contracts, the operation of the immutability principle on a domestic and international level, and the common-law approach to the recognition of postnuptial contracts and spousal donations. , Thesis (LLM) -- Faculty of Law, Law, 2023
- Full Text:
- Date Issued: 2023-03-29
The prevalence of alcohol use disorders among university students in developing countries: a systematic review and meta-analysis
- Authors: Ndlovu, Philani
- Date: 2023-10-13
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/425019 , vital:72202
- Description: High alcohol misuse is associated with many challenges, including (a) unsafe sex, problems with the criminal justice system, absenteeism, academic failure, death, injury, and alcohol related harm, both in the developing and developed world. Despite the above, no meta-analysis had been conducted in the literature to comprehensively study the prevalence of Alcohol Use Disorders (AUDs) amongst university students in the developing world. This study reviewed literature related to AUDs among university students in developing countries. It described the concept of AUD and the harmful effects of excessive alcohol use, including biological, cognitive, psycho-social, and economic impacts on the individual and the family. , Thesis (MA) -- Faculty of Humanities, Psychology, 2023
- Full Text:
- Date Issued: 2023-10-13
The possible effect of insecticide drift from citrus orchards, and acute toxicity of insecticides on the biocontrol agents of Pontederia crassipes (Mart.) Solms-Laub (Pontederiaceae) established along citrus orchards in the Lowveld region of Mpumalanga Province, South Africa
- Authors: Mabuza, Mefika Michael
- Date: 2023-10-13
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/424468 , vital:72156
- Description: This study investigated the possible effect of insecticide drift on naturalized biological control agents of Pontederia crassipes (Mart.) Solms-Laub (Pontederiaceae), in the Lowveld region of Mpumalanga Province of South Africa. Occurrence and abundance of biocontrol agents were recorded at three sites on the Crocodile River and at three dams adjacent to citrus orchards. Leaves of P. crassipes and water samples were collected for insecticide residues and also nutrient status of the water and plants. Eccritotarsus catarinensis Carvalho (Hemiptera: Miridae), Neochetina spp. (combined) (Coleoptera: Curculionidae), and Orthogalumna terebrantis Wallwork (Sarcoptiformes: Galumnidae) were recorded with notable variation in abundance between the river and dams across regions. Insecticide residues were not detected on all leaves sampled across study regions, however, nutrients were detected with nitrate ranging between oligotrophic and mesotrophic. Phosphorus was also detected, but, neither of the nutrients correlated with the occurrence and abundance of naturalized biological control agents of P. crassipes. Bioassays were conducted to measure the effect of commonly used insecticides (viz. Methomyl and Chlorpyrifos) on the survival and feeding damage of biological control agents of P. crassipes. Survival of individual insects was recorded between 0.5 and 120 hours for Megamelus scutellaris and Neochetina eichhorniae Warner (Coleoptera: Curculionidae) adults for treatments where insecticides were topically applied onto the insects or leaves were dipped into the pesticides. Concentrations below field rates, recommended and above field rates of Methomyl and Chlorpyrifos on either exposure techniques significantly reduced survival and feeding of biocontrol agents. Methomyl was more toxic compared to Chlorpyrifos and it significantly reduced the survival of M. scutellaris and N. eichhorniae. In conclusion, in this study, population abundance of biocontrol agents of P. crassipes at the Lowveld region of Mpumalanga was not influenced by pesticide drift, but, insecticides commonly used in the citrus orchards has the potential to negatively impact naturalized biological control of P. crassipes as demonstrated by the bioassays. , Thesis (MSc) -- Faculty of Science, Zoology and Entomology, 2023
- Full Text:
- Date Issued: 2023-10-13
The portrayal of migrants and liminality in Nadifa Mohamed’s Black Mamba Boy, The Orchard of Lost Souls and The Fortune Men
- Authors: Fühner, Melissa Ashleigh
- Date: 2023-10-13
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/425056 , vital:72205
- Description: This thesis argues that the characters in Nadifa Mohamed’s oeuvre exhibit both vulnerability and agency and that their position in society oscillates as if between two poles, as they cross social and spatial boundaries. There is no existing scholarly research that focuses on child migrants in Mohamed’s texts specifically. Here, Black Mamba Boy, The Orchard of Lost Souls and The Fortune Men are analysed and compared with a central focus on the child migrant characters to examine her portrayal of conflict-induced migration and its impact on vulnerable communities. In Black Mamba Boy, Mohamed portrays Jama’s exilic journey where he leaves his homeland of Hargeisa and migrates across territorial borders in Northeast Africa to find his father. His quest brings him from Somaliland to Sudan as he walks through countries that are devastated by the war between the British and Italian colonial forces in the 1930s. As Jama attempts to cross the spatial distance between himself and his father he also treads the invisible line between life and death. Along his journey, Jama is exploited and abused by colonial troops and traumatised by the conflict he witnesses. Mohamed revisits her father’s precarious journey not to portray him as a victim but to make him “a hero, not the fighting or romantic kind but the real deal, the starved child who survives every sling and arrow that shameless fortune throws at them” (1). Thus, the text is an account of Jama’s strength as he miraculously survives the brutalities of war. Similarly, in The Orchard of Lost Souls, the child protagonist, Deqo, is a refugee with parents. She internally migrates through Hargeisa at the moment the region breaks out into the Somali Civil War. Deqo attempts to keep herself out of harm’s way as the town is destroyed by soldiers and rebel groups who have opened fire against civilians. As a female child migrant Deqo occupies a particularly vulnerable position as she navigates a space where gender-based violence is used as a method of war. Despite the dangers around her, Deqo actively seeks out safety and a path that will free her from the tightening grip of the war. The Fortune Men depicts Mahmood’s journey of migration as an adult. When he attempts to cross the border into Wales he is ostracised, abused, and dehumanised because of his difference. Jama and Deqo’s exilic journeys are compared to Mahmood’s unsuccessful migration and the children cross borders that adults cannot cross because they use their vulnerability to seek out opportunities and change their environment. This thesis is situated within the theoretical framework of transnational and diasporic literature with a specific focus on the impact of forced migration on child migrants. Through close engagement and comparison of the three primary ii texts mentioned, this thesis demonstrates the vulnerabilities and fluctuating agencies of characters to highlight their liminal positioning. , Thesis (MA) -- Faculty of Humanities, Literary Studies in English 2023
- Full Text:
- Date Issued: 2023-10-13
The photodynamic therapeutic activities and optical limiting properties of metalated asymmetric porphyrins and corroles
- Authors: Burgess, Kristen Paige
- Date: 2023-10-13
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/424490 , vital:72158
- Description: Cancer is a devastating disease that is a leading cause of death worldwide. Despite the available cancer treatments, there is a significant need to improve the therapeutic approach towards this disease. Photodynamic therapy (PDT) is an alternative approach for treating cancer, which requires a photosensitiser, molecular oxygen and light. Although some porphyrin-based derivatives have been approved by the United States Food and Drug Administration (FDA) and other similar agencies elsewhere for photodynamic therapy, their relatively poor photophysicochemical properties mean that there is an ongoing need for new photosensitiser dyes. Singlet oxygen photosensitiser dyes can also be used to treat bacteria that develop antimicrobial resistance in the context of photodynamic antimicrobial chemotherapy (PACT). The main aim of this study was to synthesise and characterise a series of porphyrin dyes with 4-quinolinyl, thien-2-yl and 4-bromo-thien-2-yl meso-aryl groups and their Sn(IV) and In(III) complexes, as well as their corrole analogues. Corroles are contracted macrocycles that have interesting optical properties. The corroles selected for study were found to be difficult to synthesise and purify and had unfavourable photophysicochemical properties and were thus omitted from the PDT and PACT biological applications within this thesis. High- and low-symmetry A4 and ABAB type meso-tetraarylporphyrins porphyrins were synthesised to improve the photophysicochemical properties of the photosensitisers; the utility of these dyes as photosensitisers was studied against the MCF-7 breast cancer cell line for PDT and against Staphylococcus aureus and Escherichia coli for PACT. The thienyl-2-yl rings were introduced to red shift the lowest energy Q band towards the phototherapeutic window, while quaternisation of the nitrogen and sulfur atoms of the 4-quinolinyl and thien-2-yl rings to introduce a cationic nature was explored to improve the bioavailability of the drugs and uptake into the target cell walls for improved efficacy. Heavy Sn(IV) and In(III) central metal ions were introduced to enhance the singlet oxygen quantum yields and limit aggregation through axial ligation. The bromine atoms of the 4-bromo-thien-2-yl meso-aryl rings were also introduced to enhance the singlet oxygen quantum yields of the dyes. Furthermore, the utility of the porphyrin and corrole molecules for optical limiting properties to limit laser radiation to protect optical devices, including eyes, was explored by the z-scan technique. One of the dyes studied, Sn(IV) tetrathien-2-ylporphyrin, that exhibited the most favourable reverse saturable absorbance (RSA) response was embedded into a poly(bisphenol carbonate A) polymer thin film to further explore its suitability for practical applications. , Thesis (MSc) -- Faculty of Science, Chemistry, 2023
- Full Text:
- Date Issued: 2023-10-13
The perspectives of some amaXhosa healthcare workers regarding mental distress: an interpretive phenomenological analysis
- Authors: Ngqamfana, Siphosethu
- Date: 2023-10-13
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/425031 , vital:72203
- Description: Mental distress is a universal phenomenon experienced by many individuals despite age, race, gender, occupation, or socio-cultural context and is slowly becoming a major contributor to the burden of disease in South Africa. However, mental distress fails to take precedence in SA because of inherent intricacies in understandings about it, as a result of ways of being conceptualised and interpreted differently across cultures. This research study explored amaXhosa healthcare workers’ understandings, knowledge, practices, and attitudes regarding mental distress amongst some amaXhosa people. The study aimed to investigate what mental distress means for some people who belong to the amaXhosa ethnic group, to uncover how they conceptualise mental distress, seek help or what behaviours prevent help-seeking. It aimed to highlight any prevalent attitudes of stigma and discrimination, to build insight into overlooked aspects in psychotherapy practice especially when dealing with non-western populations. The study utilised interpretative phenomenological analysis (IPA) as its analytical lens; to explore and to enter as far as possible into the worlds of participants to generate rich data and in-depth analysis. Four participants were recruited through both purposive and snowball sampling and data were gathered using individual semi-structured interviews. From the data collected, the findings illustrate a limited understanding of mental distress amongst some amaXhosa people due to lack of education and awareness on the subject, leading to the apparent silence in discussing such matters and inadvertently predisposing it to being viewed as taboo. The predominant themes as evidenced by the data were the use of language that sensationalises mental distress; misinformation; Afrocentric beliefs that rationalise mental distress; alienation and segregation of those affected; and the primary healthcare system as a source of reinforcing prevalent stigma and discrimination. The findings show a link between constructs around mental distress and the prevalent socioiii cultural environment, denoting that some perspectives can be linked to observations or modelling in childhood, from people in the respective communities in which people live. , Thesis (MA) -- Faculty of Humanities, Psychology, 2023
- Full Text:
- Date Issued: 2023-10-13
The obligation of South Africa to provide social security to refugees and asylum seekers during the COVID-19 pandemic
- Authors: Dekeda, Awethu Zethu
- Date: 2023-10-13
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/424119 , vital:72125
- Description: Covid-19 a novel pandemic, has wreaked havoc globally, threatening the livelihoods of all, including refugees and asylum seekers. Like all other countries globally, South Africa has gone to great lengths to mitigate the challenges that this pandemic has caused. However, it is far from clear whether these responses are according due regard to the rights of some of the most vulnerable in society, amongst which are refugees. This thesis deals with South Africa’s obligation to provide social security to refugees during the Covid-19 pandemic. It specifically assesses whether South Africa's responses to the Covid-19 pandemic were in adherence to fundamental refugee law principles relevant to the protection of refugees. The study commences with a general introduction, followed by an analysis of the international human rights and refugee law framework relevant to protection of refugees. This framework is used to assess South Africa’s responses. Subsequently, the discussion delves into South Africa’s own national framework on social security. Using the standards identified in both the national and international frameworks, the thesis then proceeds to measure South Africa’s Covid-19 related responses regarding social security to resolve the issue of whether South Africa adhered to these standards in as far the protection of refugees’ right to social security is concerned. , Thesis (LLM) -- Faculty of Law, Law, 2023
- Full Text:
- Date Issued: 2023-10-13
The novobiocin-induced turnover of fibronectin via low density lipoprotein receptor-related protein 1 alters matrix morphology with physiological consequences on cell growth and migration
- Authors: Boёl, Natasha Marie-Eraine
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/114778 , vital:34034 , 10.21504/10962/114778
- Description: Fibronectin (FN), an extracellular matrix protein, is secreted as a soluble dimer which is assembled into an insoluble extracellular matrix. The dynamics of FN matrix assembly and degradation play a large role in cell migration and invasion thereby contributing to the metastatic potential of cancer cells. Previous studies have shown the direct binding of Heat Shock Protein 90 kDa (Hsp90) and FN in vitro, and that inhibition of Hsp90 with novobiocin (NOV) caused internalisation of the FN matrix. Low density lipoprotein receptor-related protein 1 (LRP1) is a ubiquitous receptor known to bind both Hsp90 and FN. Using an LRP1 expressing Hs578T breast cancer cell line and an isogenic mouse embryonic fibroblast (MEF) model system of differential LRP1 expression we demonstrate that LRP1 is involved in turnover of FN in response to C-terminal Hsp90 inhibition. The first objective of this study was to identify the mechanism of NOV-induced LRP1-mediated FN turnover. Our data show that NOV-mediated FN turnover via LRP1 did not require the activity of matrix metalloproteinases (MMPs), which play an important role in processing and degradation of the extracellular matrix and FN. In addition, the levels of the main FN receptor responsible for its extracellular assembly, β1-integrin, did not change in response to NOV. LRP1 is known to undergo regulated intramembrane proteolysis (RIP) which generates smaller fragments that may translocate to the nucleus and modulate gene transcription. Using inhibitors of LRP1 cleavage and nuclear fractionation we determined that LRP1 processing was not required for the NOV-induced FN response suggesting that a mechanism unrelated to LRP1 RIP is involved. A possible mechanism may be in altered Hsp90-LRP1 cell signalling as we observed disruption of the FN-Hsp90-LRP1 complex at the cell surface in NOV treated cells. How this affects downstream eHsp90-LRP1 signalling is still to be determined but may be related to a significant increase in phospho-AKT and loss of phospho-ERK upon NOV-treatment; two key signalling proteins involved in FN matrix regulation and which are downstream of LRP1 signalling. The second objective of this study was to determine the physiological consequences associated with FN turnover in response to NOV treatment. Using migration assays we demonstrated that levels of insoluble matrix-associated FN and FN concentration are not solely responsible for migratory capacity of cells on decellularized extracellular matrices, but rather that structural composition and integrity of the matrix plays a bigger role. Using confocal and scanning electron microscopy, we identified NOV treated matrices to be flatter, less mature and contain thicker, rope-like FN fibrils to which cells adhered better but were generally less proliferative. Comparatively, cells adhered less to the more mature and 3-dimensional untreated matrices but exhibited increased spreading and cell growth, which may in part be due to the thinner fibrils and web-like matrix. In summary, this study substantiates the role of LRP1 in NOV-mediated FN turnover, and provides new insights into the possible mechanisms of the Hsp90-LRP1 mediated loss of FN matrix. This is the first study to demonstrate some of the functional consequences related to FN turnover by NOV at the ECM level. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2020
- Full Text: false
- Date Issued: 2020
The nature of Visual Representations of multiplication and division exercises in nine Grades 1 to 3 South African textbooks
- Authors: Booysen, Tammy Irene
- Date: 2023-03-29
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/422579 , vital:71959
- Description: Mathematics is a language that is rich in visual representations (Mudaly & Rampersad, 2010). Visual Representations assist us in developing our reasoning skills when solving a problem and our understanding of the relationships between concepts (Ozkan et al., 2018). This thesis focuses on the different visual representations (VR) in South African Foundation Phase mathematics textbooks and workbooks. Textbooks and workbooks play an important role in developing an understanding of mathematical concepts for both teachers and learners (Harries & Spooner, 2000). While teachers generally rely heavily on textbooks, they were a key resource while schools were closed due to COVID-19 lockdown regulations. The theory of Constructivism forms part of the theoretical framework for this study. Constructivism advocates that learners actively construct knowledge through experiences rather than passively receiving knowledge from the outside (Von Glaserfeld, 2001). Vygotsky believed that social interactions create experiences that facilitate the learning and meaning-making process (Vygotsky, 1978). This case study is underpinned by an interpretivist paradigm as it sought to examine the nature of VRs in three Grades 1 - 3 textbooks/workbooks. My research approach is primarily qualitative with descriptive statistics to assist in developing a more comprehensive understanding of the research questions. The study was guided by the analytic tool designed by Fotakopoulou and Spiliotopoulou (2008) which I adapted for Foundation Phase mathematics use. The framework provides insight on the type of VR, VRs relation to content, VRs relation to reality, the function of the VR and dimensionality of a VR. While the workbooks had many more VRs than textbooks, the dominant type of VR in textbooks and workbooks are images. The VRs mostly have a strong relation to content with a realistic relation to reality as they were predominantly 2D representation of a 3D object that had an exemplifying function (type b). , Thesis (MEd) -- Faculty of Education, Education, 2023
- Full Text:
- Date Issued: 2023-03-29