Beneficiary perceptions regarding farm worker equity share schemes in South Africa
- Authors: Xolo, Siyavuya Nicholas
- Date: 2018
- Subjects: Investments -- South Africa , Investment analysis Land reform -- South Africa Agricultural laborers -- South Africa
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/36323 , vital:33920
- Description: The study aimed to assess beneficiary perceptions regarding farm worker equity share schemes in South Africa. Farm worker equity share schemes started in the early 1990s with the aim of having a special arrangement pertaining to the ownership and operation of a farm between the farmer and the farm workers. This was intended to assist farm workers in not only remaining as farm workers but also to gain ownership of the farm. This could lead to the empowerment of farm workers, better working conditions, improved living standards and their rights to land ownership. Farm worker equity share schemes have been widely reported as having failed to meet their intended objectives, thus, in 2009, the Department of Rural Development and Land Reform initiated a study to assess the implementation of equity share schemes. Although the report was not made public, it reports that out of the 88 equity share schemes at the time, only nine managed to pay dividends ranging from R200 to R2000 per year. As a result, the Department of Rural Development and Land Reform put a moratorium on equity share schemes; this was however removed in 2011. It is against this background that this study was undertaken to assess beneficiaries’ perceptions regarding farm worker equity share schemes in South Africa. A positivistic research paradigm was employed in this study, by means of quantitative research. Secondary data in the form of textbooks, journal articles and Internet sources provided the theoretical framework for this study. Primary data was obtained using the survey method, by means of self-administered structured questionnaires. Convenience and purposive sampling were applied in order to select 20 farms that use equity share schemes. The farms selected for this study were located in the Eastern Cape, Gauteng, Mpumalanga and the Western Cape provinces, covering a variety of farming activities such as citrus fruits, crops, vegetables and wineries. Ideally, a total of 15 farm workers per farm were targeted. However, due to a variation in these farm worker equity share schemes, on some farms less than 15 workers and in others more than 15 workers were selected for the study; this resulted in a total sample size of 341 farm workers. Ten null-hypotheses and a hypothetical model of beneficiary perceptions regarding farm worker equity share schemes were tested. The influence of seven independent variables were tested, these are: stakeholder trust, operational risks, government interventions, two-way communication, farm worker empowerment, training and skills development, and access to resources on farm worker equity share schemes. In addition, the influence of farm worker equity share schemes on three dependent variables, namely, farming performance, sustainability and employee expectations were tested. The Statistica (version 13.2) computer programme was used to analyse the results by means of advanced statistical techniques (such as exploratory factor analysis, regression and correlation analyses) as well as descriptive analysis and frequency distributions. After various statistical procedures, the model was re-specified; some of the variables were then renamed and the hypotheses were adjusted accordingly. The empirical results showed that three key variables to the success of farm worker equity share schemes are stakeholder trust, government interventions and farm owner support. It was determined that these key variables could lead to increased farming performance, farming sustainability and meeting employee expectations. This study provided useful and practical guidelines to farm owners and administrators of equity share schemes, so as to ensure effective strategising that could enhance their competitiveness and long term survival. The findings of this study could inform strategy policy formulation and implementation in the agricultural sector, as pertaining to farm worker equity share schemes. The study used a sound and well-developed research design and methodology, which has been justified and successfully applied to this research; this method can be utilised by other similar studies to conduct empirical research in the field of farm worker equity share schemes. It is envisaged that the results and recommendations of this study could be used to implement effective strategies that could ensure the effective functioning of farm worker equity share schemes in South Africa.
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- Date Issued: 2018
Synthesis of folate-conjugated palladium nanoparticles
- Authors: Xolo, Luthando
- Date: 2018
- Subjects: Nanotechnology , Nanostructured materials Complex compounds
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/36442 , vital:33943
- Description: In this study, the synthesis of two new folate-conjugated palladium (Pd) nanoparticles was carried out. This was done via two steps; firstly, the synthesis of palladium nanoparticles (PdNPs) capped with 4-aminothiophenol (4-Atp) and secondly, they were conjugated to the folate to form Folate-4Atp-PdNPs. All the above were characterized by using Fourier Transform Infrared spectroscopy (FTIR) which confirmed the formation of the targeted product (PdNPs-4-Atp-folate) as well as the 2-Aet linked with folate product (2-Aet-folate). The optical properties of the products formed were characterized further by using UV-Vis spectroscopy and Photoluminescence (PL). The size and shape of the nanoparticles were obtained by Transmission Electron Microscopy (TEM). The FTIR confirmed the formation of desired nanoparticles (Fa-4Atp-PdNPs), with peak of C=O stretching vibration at 1659 cm-1. The UV-Vis showed absorption peaks at 236 nm and 285 nm which was due to n-π* and π-π* transitions. The nanoparticles also showed excitation and emission peaks at 360 nm and 455 nm from the PL when excitation wavelength was set at 270 nm. The methanol soluble nanoparticles had an average size of 36 nm while the water-soluble nanoparticles were 4 nm in size. The HRTEM also showed the methanol nanoparticles were amorphous while the water-soluble nanoparticles were crystalline. The work reports on comparison of the methanol-soluble and water-soluble nanoparticles size distribution and the effect of capping agent used on the nanoparticles.
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- Date Issued: 2018
Ratifying the ILO convention no. 102 (social security minimum standards convention, 1952) by South Africa
- Authors: Xakaxa, Xoliswa
- Date: 2018
- Subjects: Social security -- South Africa , Social security -- Law and legislation -- South Africa Labor laws and legislation, International
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: http://hdl.handle.net/10948/36452 , vital:33945
- Description: Twenty-three (23) years have elapsed since South Africa parted ways with the apartheid system. Nevertheless, poverty, inequality, and unemployment pose the greatest threat to human dignity and social cohesion. Section 27 (1) (c) of the Constitution obligates the state to develop a comprehensive social security system. It affirms the universal right to access social security, including appropriate social assistance for those unable to support themselves and their dependants. It orders the state to take reasonable legislative and other measures, within its available resources, to achieve the progressive realisation of these rights. The underlying normative commitment of social security is the improvement of the quality of life of the population by promoting economic or material equality. The study provides a general overview of the system of Social Security in South Africa as a Member State of the ILO. In particular, the study underscores that South Africa has not ratified ILO Convention No. 102 Social Security (Minimum Standards) Convention, 1952 and other Conventions relevant to Social Security. The study examines the need to ratify the said Convention in order to receive extensive coverage that would, among other benefits receive guarantees for a well-established system and thereby potentially reduce poverty. The Constitution is the supreme law of the country, it clearly stipulates that when interpreting, and applying the statutes international law must be considered. The study illuminates the significant benefits the country would receive from ratifying Convention No. 102.
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- Date Issued: 2018
The impact of leadership on job satisfaction at a specific bank in the Eastern Cape
- Authors: Wyngaard, Shaun Peter
- Date: 2018
- Subjects: Leadership , Bank employees Job satisfaction , Labor turnover , Transformational leadership , Bank management South Africa Eastern Cape
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/62050 , vital:28099
- Description: This study aimed at investigating the relationship between leadership and employee job satisfaction in the banking sector of South Africa. The study drew from the fact that there is a growing emphasis in organisations to reduce employee turnover by keeping their employees satisfied. The ultimate performance, effectiveness and competitiveness of an organisation are directly related to an organisation’s ability to keep its employees optimally productive and satisfied. Numerous research studies have been conducted on transformational, transactional and passive-avoidant leadership to determine the significance of their respective relationship with the job satisfaction of employees in different scenarios. Results show that the transformational leadership style has a significant relationship with job satisfaction; while the transactional leadership style or the passive-avoidant style are applied according to changing circumstances. The study adopted a quantitative approach, using online questionnaires as an instrument for collecting primary data. The target population of the study was 380 bank employees, and the target sample was 218; 121 questionnaires were completed and used as the actual final sample. Questionnaires were completed from managers and employees of the selected bank, with the two population groups being investigated using different scales. SPSS was used in analysing the collected data. The findings of this research showed that the leadership styles under investigation have a direct impact on the job satisfaction of employees. Transformational leadership was found to have a significant positive relationship with job satisfaction, while the relationship between transactional leadership and job satisfaction was positive but moderate. A significant negative relationship was found between passive-avoidant leadership and job satisfaction. It is thus the responsibility of the financial institution under investigation to highlight the significant links and benefits of this leadership style to its management to ensure increased job satisfaction and lower turnover of employees in the institution. Literature explored in this study supported the close link between the different leadership styles and job satisfaction.
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- Date Issued: 2018
The experiences of recently diagnosed HIV-positive individuals, as shared on an online forum
- Authors: Wylde, Charlotte Anne
- Date: 2018
- Subjects: HIV-positive persons Social networks , HIV infections Diagnosis Psychological aspects , HIV infections Social aspects , HIV infections Electronic discussion groups , Internet Social aspects , Stigma (Social psychology) , Phenomenological psychology
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/60222 , vital:27756
- Description: An HIV-positive diagnosis can be an overwhelming and traumatic experience. This study explores the experiences of receiving an HIV-positive diagnosis. Employing an Interpretative Phenomenological Analysis (IPA), a sample of the initial posts from threads on an online forum, was collected and explored, in order to determine the dominant themes from the experiences expressed in the posts, as well as the support sought from the forum. The online forum was accessed as an unobtrusive observer, and posts from January to December 2015 were explored. The online forum provides a platform for disclosure following an HIV-positive diagnosis, when anxiety and fear of stigma can impact on an individual’s ability to disclose to their social support network of family and friends. The experiences expressed on the online forum reflect the emotional, mental and physical impact of an HIV-positive diagnosis on an individual. The findings in this study reflected themes of shock, guilt and hopelessness, and concerns and fears regarding disclosure and stigma associated with HIV, as well as the importance of social support for the coping mechanisms of individuals after receiving an HIV-positive diagnosis. This research demonstrates the importance of Internet accessibility for information and support for chronic illnesses, such as HIV, and the role of the online forum platform for providing a safe environment for individuals recently diagnosed HIVpositive.
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- Date Issued: 2018
Pharmacist perceptions of pharmacy support personnel in the pharmaceutical manufacturing sector in Port Elizabeth
- Authors: Worthington, Nicole
- Date: 2018
- Subjects: Pharmacists -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10948/42434 , vital:36659
- Description: Pharmacy support personnel (PSP) are employed across multiple pharmaceutical sectors in South Africa. They assist pharmacists in the manufacturing sector, while under their direct, personal supervision, to carry out the pharmacists’ functions listed in the South African Good Manufacturing Practice guidelines, within a defined scope of practice. Prior to 2013, all PSP training was workplace-based. The recent introduction of a university-based qualification for PSP has resulted in two routes for students to qualify as PSP. This study employed a qualitative, phenomenological design using semistructured interviews with pharmacists employed in pharmaceutical manufacturing. Their perceptions regarding PSP who had trained via the two training routes where interpreted through thematic analysis in order to determine whether a perceived difference in the abilities of the two cadres of PSP exists. Pharmacists generally expressed a more positive perception of PSP who qualified through the university-based programme. Strengths and weaknesses of both routes of training were identified, with areas of possible improvement identified for both programmes. Furthermore, a mutually supportive pharmacist – PSP relationship was deemed important in order to achieve optimal functionality in the workplace. The need for both pharmacists and PSP to be made aware of the roles that they play in this relationship was highlighted.
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- Date Issued: 2018
The evolution of fashion discourse: examining vogue magazine’s role as fashion authority
- Authors: Wissink, Emma Seline
- Date: 2018
- Subjects: Fashion -- Research , Fashion -- Forecasting Clothing trade -- Forecasting Advertising -- Fashion Fashion writing
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/36026 , vital:33883
- Description: The aim of this study was to investigate the evolution of Vogue magazine’s role as a fashion authority. The methodology of Foucauldian discourse analysis motivated the enquiry into the establishment of Vogue’s fashion authority over time. The corpus of Vogue’s September Point of View editorials between the period of 1960 and 2015 was divided into four epochs using the period of editorship held by the four editors (Jessica Daves, Diana Vreeland, Grace Mirabella and Anna Wintour). Features of Vogue’s discourse were identified in literature and applied to the corpus using a concurrent embedded mixed methods approach, employing the quantitative and qualitative methods of content and discourse analysis respectively. The analysis suggested that Vogue maintained fashion authority through changing its discourse to suit changes occurring in the field of fashion and the evolving needs and perspectives of the reader. Changes in the way Vogue presents itself; addresses the reader; attributes material, commercial, or intellectual features to fashion; addresses concepts of time and novelty; and negotiates the relationship between American fashion and European or global fashion were the focus of the analysis. The findings conceptualise Vogue’s voice as evolving through the four roles of reporting, fictionalizing, translating and connecting fashion. The shift in Vogue’s voice suggests that the conceptualization of fashion in the publication shifts towards a more abstract and general conception of fashion and reader. The results suggest that Vogue’s fashion discourse shifts from a focus on the specific material features of fashion and craft and the conception of fashion as news and Vogue as a reporter towards a focus on the more abstract, general intellectual and commercial properties of fashion and the conception of fashion as commerce promoting Vogue’s role as a facilitating platform.
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- Date Issued: 2018
Monetary policy and microfinance in Sub-Sahara Africa: Ghana’s perspective
- Authors: Wiredu, Nana Kwame
- Date: 2018
- Subjects: Monetary policy -- Ghana , Microfinance -- Ghana Ghana -- Economic policy
- Language: English
- Type: Thesis , Masters , MPhil
- Identifier: http://hdl.handle.net/10948/36037 , vital:33884
- Description: Ghana, like many other developing countries in Sub-Sahara Africa, recognises the important role that the micro, small and medium-sized enterprises (MSMEs) play in economic development. These enterprises need an environment conducive to thriving and growth, to contribute to employment and overall output. A key pillar to this is access to affordable credit. Credit in itself is thought to be affected by monetary policy formulated and put forth by the central bank, on behalf of government. The pass-through effect of monetary policy on commercial banking rates, as charged by bank and non-bank financial institutions (NBFIs), is a concern for MSMEs. Therefore, this study sought to highlight cause and effects relationship between monetary policy, the lending rate and private sector credit, and also sought to find a possible cushion for MSMEs through the microfinance targeting approach. Annual aggregate monetary time series data from the Bank of Ghana (BoG) was analysed. Multiple linear regression and analysis of variance test results reveal evidence of a significant and proportional effect of both the monetary policy rate and commercial banking rate on credit to the private sector. The key implication of the findings is that the pass-through effect of monetary policy negatively affects MSMEs. The study recommends that governments in Sub-Sahara Africa (SSA), and particularly the government of Ghana, should take into consideration the effects of monetary policy on MSMEs, when formulating monetary policies. It is also recommended that governments in SSA should formulate policies that enhance MSMEs access to adequate and affordable credit to enable it contribute more to economic growth. Perhaps, this can be done through microfinance.
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- Date Issued: 2018
Periglacial landforms of the Ahlmannryggen and Jutulsessen areas of western Dronning Maud land, Antarctica
- Authors: Wilmot, Nicola Frances
- Date: 2018
- Subjects: Periglacial processes Antarctica Queen Maud Land , Geomorphology Antarctica Queen Maud Land , Permafrost Antarctica Queen Maud Land , Freezes (Meteorology) Antarctica Queen Maud Land , Thawing Antarctica Queen Maud Land
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/61535 , vital:28034
- Description: Periglacial landforms are a common occurrence in Ahlmannryggen and Jutulsessen areas of western Dronning Maud land (WDML). Classification and formation of these landforms were disputed in literature. In Antarctica information on periglacial landforms is limited or confined to a specific landform. Thus a holistic approach was taken when investigating the periglacial landforms found in WDML. An overview of the existing knowledge base on periglacial landforms in WDML was given which was coupled with the analysis of archival data. The landforms found in this area were patterned ground, openwork block deposits (OBD), rock glaciers, terraces, a pronival rampart and lake ice blisters. With patterned ground being the common periglacial landform in WDML, heave monitoring was used where time-lapse videos were used to investigate the formation processes in patterned ground. From consolidating existing knowledge as well as adding new knowledge on the formation of periglacial landforms, it is clear that the landforms in Antarctica should not be compared to other examples, especially examples from the northern hemisphere. Further research in the formation of periglacial landforms is needed and can be further enhanced with more extensive use of the heave monitoring method in future research.
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- Date Issued: 2018
Designing writing groups to support postgraduate students’ academic writing: a case study from a South African university
- Authors: Wilmot, Kirstin
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66267 , vital:28926 , https://doi.org/10.1080/14703297.2016.1238775
- Description: publisher version , This paper reports on a writing group pilot programme implemented at a South African university. Drawing on literature, anonymous student evaluations and facilitator observations, it discusses the use of writing groups for supporting postgraduate academic writing practices. Developed within a broader postgraduate academic writing support programme, the paper discusses a case study of two pilot writing groups: a multidisciplinary long-term group and a disciplinary short-term ‘writing-intensive’ group. The findings indicate that the overall experience of the writing group was a positive one, with each group presenting varied ‘success’ aspects as well as challenges. Insights gleaned may contribute to our understanding of how these groups can be utilised to support postgraduate students and how different kinds of groups can be developed to serve particular student needs. The paper concludes with a discussion of the inclusion of a disciplinary expert, which proved particularly useful in this pilot.
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- Date Issued: 2018
Writing groups as transformative spaces
- Authors: Wilmot, Kirstin , McKenna, Sioux
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/${Handle} , vital:44576 , xlink:href="https://doi.org/10.1080/07294360.2018.1450361"
- Description: Curriculum transformation is a central concern for higher education in response to rapidly expanding technologies, globalisation and the widening diversity of the student and staff body. This is particularly true for South Africa, which is still grappling with inequalities and pressure for social redress in its universities. Early responses to supporting students took the form of add-on, ‘deficit-model’ approaches which understood poor student retention and success rates as emerging from students’ lack of neutral literacy ‘skills’. Recent initiatives have begun to adopt more socio-cultural understandings of literacy that seek to challenge traditional power structures and cultivate horizontal peer-orientated spaces for learning with a focus on practice rather than on product. Writing groups, as spaces for academic writing development, embrace this orientation and are argued to provide a transformative framework that foregrounds proactive student learning and experience, while still accommodating disciplinary learning through peer engagement. Drawing on the successful implementation of such forms of support at a research-intensive university, this paper argues that writing groups can play a critical role in both personal (student) transformation and broader curriculum transformation. Data include anonymous questionnaires and surveys with participants and coordinators of the writing groups. An inductive, constant comparative analysis indicated that students feel empowered in this space to develop not only their writing practices but also their transforming identities as scholars. Writing groups were found to provide ‘safe spaces’ where academic practices can be made explicit and where they can be challenged. The paper therefore argues that writing groups can play a small but key role in broader transformation efforts.
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- Date Issued: 2018
Isolating the consumer determinants of choice when making a purchasing decision in a supplier company
- Authors: Williams, Rita Christine
- Date: 2018
- Subjects: Customer relations , Customer services -- Management Consumer satisfaction -- Evaluation
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/36048 , vital:33885
- Description: The objective of this research was to establish the determinants of purchase choice by customers and to establish the modality of their decision-making process. The study was conducted at PerkinElmer a scientific equipment supplier company. PerkinElmer South Africa supplies equipment to industrial laboratories, academic laboratories and laboratories in government institutions. It has become clear to the researcher that understanding the customer and what their perceptions are is the key to business success. These insights would give the researcher the knowledge of important factors in the customer modality of purchase decisions. The literature review revealed that there are numerous factors that influences a customer buying decision namely: Customer relationships management, Unique selling proposition, the importance of salespeople, customer satisfaction levels, the brand name, Brand awareness, brand perception, brand loyalty, price, the service levels that the company provides after sale. The customer decision-making process and the various stages involved, an empirical study was conducted utilising in-depth interviews. The five main themes that were investigated through in-depth interviews were the following: Customer relationship management, brand, customer satisfaction levels, price, service. The factors were probed, analysed and compared and each customer’s preference was noted. The study employs a qualitative approach as this stance supports the researcher’s interest in the customer views and perceptions. A small sample was utilised from the scientific sector in the Eastern Cape and the Gauteng area. The empirical results indicated the importance of service support and if this is not in place it can mean the loss of future business. The customers in academia had the common view that the price is most important. The university policy forces the lowest priced equipment to be purchased. The respondents unanimously voiced their concerns regarding the expensiveness of PerkinElmer consumables.
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- Date Issued: 2018
Exploring teachers’ attitudes to implementing blended learning: a case study
- Authors: Williams, Monique
- Date: 2018
- Subjects: Blended learning -- South Africa , Educational technology -- South Africa Education, Higher -- South Africa Internet in education
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10948/35829 , vital:33851
- Description: One of the many characteristics of the 21st century learner is that they are highly technologically skilled. This characteristic poses today’s teachers with many challenges in order to teach these learners and create optimal learning experiences. It is evident that teachers have their own preferred teaching methods which they believe work best and some teachers teach the way that they were taught at school in ways that have become part of their habitus. Blended learning is a teaching method that can promote effective learning experiences in the 21st century learning environment. This study focussed on teachers’ experiences with blended learning and their current ideas on how learners learn optimally and whether the practice of blended learning changed their ideas of learning. Furthermore, the study determined the teachers’ present technology acceptance and established teachers’ personal views regarding the challenges that teachers face to teach 21st century skills, what they think 21st century teaching is about and new insights on dealing with these challenges. Through experiencing blended learning teachers who made use of a textbook based teaching method made shifts not only to a blended approach, but also shifted their thinking away from what they prefer to what learners get out of the learning experience. Although challenges occur when using a blended teaching approach, their experiences with blended learning were mostly positive and they found learners to be more involved in the learning process. These outcomes created feelings of worthiness in the teachers since they create such positive learning opportunities for their learners. Although the teachers made shifts, some teachers continue to have a fear of technology since they had not received adequate training to incorporate technology into their teaching approaches. It is crucial for the DBE and schools to provide teachers with opportunities to improve their technological skills in order for teachers to create opportunities for blended learning experiences for the 21st century learner
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- Date Issued: 2018
Information needs of undergraduate nursing students at the point of care for clinical decision making
- Authors: Williams, Marie Rosalina
- Date: 2018
- Subjects: Nursing students -- South Africa , Nursing -- Study and teaching -- South Africa Clinical competence -- South Africa Information services -- South Africa -- Students
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10948/23315 , vital:30527
- Description: A need was identified to assess the perceptions of fourth year nursing students regarding the information required by undergraduate nursing students at the point of care for clinical decision making. A qualitative, exploratory, descriptive and contextual design was used to conduct this study. The research population comprised of all fourth year nursing students who have been subjected to experiential learning in the various clinical areas during their four years of training. Data was collected by means of in-depth interviews from a purposively selected sample and then analysed using the steps of qualitative data analysis described by Tesch (1990). A pilot study was conducted prior to the main study to determine whether the sampling and interviewing techniques of the researcher as well as the research question, were adequate for data collection. Trustworthiness was ensured by utilising Guba and Lincoln’s (1985) strategies of credibility, dependability, transferability and conformability. Strategies to ensure respect for persons, beneficence and justice were implemented throughout the study. The findings of the study was categorised into two main themes. Theme one; Participants shared their various experiences regarding information needed at the point of care. This theme had five sub-themes which were discussed in detail in chapter three. The second theme was; Participants offered suggestions to address their information needs at the point of care. This theme had four sub-themes and was discussed further in chapter three. The study concludes with recommendations made to the Department of Nursing Science at the Institution where the study was conducted to address clinical practice, education and future research.
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- Date Issued: 2018
The impact of social grants in poverty alleviation: the case of child support grants in Lusikisiki
- Authors: Williams, Antonia Nomthandazo Hycinth
- Date: 2018
- Subjects: Poverty -- Economic aspects -- South Africa -- Eastern Cape Child support -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/19542 , vital:28892
- Description: This study investigates the impact of the impact of Social Grants in poverty alleviation; a case in point is the Child Support Grants in Lusikisiki. Poverty is characterized by an increase in depravation, unemployment and inequality. Social Security has been introduced as a social safety net that reduces the severity of poverty. The study uncovers the significance of the Child Support Grant in sustaining families and meeting their basic human needs. The study further shows that the Child Support Grant is a reliable monthly cash injection that benefits the children and other people in the households. It gives hope, allows beneficiaries to make choices and enables them to take care of themselves and their families, therefore restores dignity. The additional support provided to the Child Support Grant recipients promotes human development and improves access to education and health. The Child Support Grant has a significant impact on poverty alleviation.
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- Date Issued: 2018
An exploratory study of students’ expectations and perceptions of service quality in a South African higher education institution
- Authors: Williams, Alyssa Shawntay
- Date: 2018
- Subjects: SERVQUAL (Service quality framework) , Relationship marketing , Consumer satisfaction , Sampling (Statistics) , College students Attitudes , Universities and colleges South Africa
- Language: English
- Type: text , Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/63844 , vital:28496
- Description: Within the past few years, higher education institutions have come under an exorbitant amount of pressure to restructure, increase funding and grow student numbers, whilst still preserving the service quality they offer. The purpose of this study is to measure students’ expectations and perceptions in a higher education institution and establish how significant of a gap exists between what is expected and what is perceived. The instrument utilised within the present study is SERVQUAL. A convenience sampling approach was adopted, furthermore, both descriptive and inferential statistics were used to analyse the data pertaining to the objectives concerning students’ gap between expectations and perceptions and hypotheses regarding the gap between students’ differences in each faculty, respectively. The study found that there were gaps in all dimensions with the order being, from highest to lowest: Reliability – Responsiveness – Assurance – Empathy – Tangibility. In addition, the significant difference in means according to faculty was established and the only dimension with a significant difference was Empathy. These results were used to offer recommendations to management, faculties and departments of the higher education institution under study about where they are deficient, consequently, improving their services to enhance their service quality and increase their competitive advantage but without financial strain. Overall, the conclusions the present study reached was that students and higher education institutions need to have a mutual interest in their relations. This means that as much as higher education institutions need to provide high service quality to students, students need to be willing to provide feedback and interact.
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- Date Issued: 2018
Weight gain in hospitalised low birth weight (LBW) premature infants receiving breast milk or breast milk with human milk fortifier in the Nelson Mandela Bay Health District
- Authors: Wicomb, Ra-eesa
- Date: 2018
- Subjects: Premature infants -- South Africa -- Nelson Mandela Bay Municipality , Birth weight, Low -- South Africa -- Nelson Mandela Bay Municipality Birth weight -- South Africa -- Nelson Mandela Bay Municipality Infants -- Nutrition Children -- Nutrition -- Research
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/23327 , vital:30529
- Description: Rationale: Worldwide, hospitals with premature units have one generalised objective, i.e. to achieve postnatal growth and body composition similar to that of a normal foetus of similar gestational age. Optimal nutrition leads to optimal neurodevelopment and breastfeeding (BF) is known as the golden standard for infant nutrition. Human breast milk (BM) has significant value for preterm and term infants and is of special benefit to HIV infected mothers. Maternal supplementation is provided as part of the standard protocol in certain hospitals in the Eastern Cape province to those mothers who breastfeed their low birth weight (LBW) infants after delivery. human milk fortifier (HMF) is a nutritional supplement that is added to expressed breast milk for feeding preterm infants in order to meet their high energy and protein needs and therefore supporting the recommended growth velocity of 10g/kg/day-15g/kg/day. Some hospitals within South Africa provide HMF to preterm infants as part of their standard nutritional protocol in order for the infant to gain weight if BM only failed to produce adequate results. To date, little to no South African studies support or discourage the use of HMF for LBW infants. This study aimed to describe the effect of maternal supplementation compared with breast milk with HMF, or a combination of maternal supplementation and breast milk with HMF, on growth velocity in hospitalised LBW premature infants within the Nelson Mandela Bay health district. The proposed study design followed a longitudinal, observational, descriptive study in a cohort of LBW infants. The study was analytical using quantitative empirical data. Study participants were selected, by using convenience sampling, at Dora Nginza Hospital, Zwide between October 2015 and August 2016 (ethics approval: EC_2016RP27_564). Quantitative data on anthropometric measurements was collected from study participants. Primary care givers provided written informed consent. Registered nurses were trained and performed anthropometrical measurements according to standardised methods. A structured questionnaire was completed by the principal reasarcher as a source of data collection. Numerical data was described using means and standard deviations. Chi squares were used to describe the associations between maternal risk factors and birth weight outcomes. ANOVA was used to determine the relationship between growth velocity and the various supplementation groups. A sample size of 91 LBW preterm infants and mother pairs were entered into this study. The majority of mothers, 64% (n=58) fell in the age category of 20-35 years old. Of the total maternal sample (n=88), 35% (n=31) were classified in the at risk age category, i.e. <20years old and >36years old. Out of the total infant sample (n=91), 65% (n=59) was classified as VLBW, 22% was LBW and 22% (n=20) was ELBW. No statistically significant association was found between infant growth velocity and maternal risk factors. The group receiving BM with HMF had a mean growth velocity of 19.75 g/kg/day (SD=6.45) that was statistically significantly (p<0.05) more than the other groups. The maternal supplementation only group and the maternal supplementation and BM fortification group showed mean growth velocities of 12.26 g/kg/day (SD=5.41) and 12.29 g/kg/day (SD=6.97) respectively. A post hoc test was done between growth velocity in the supplementated groups and the length of hospital stay. These results reveal that the group receiving BM with HMF had a significantly (p<0.05) shorter mean length of hospital stay of 11.29 days (SD=7.02), compared with the group on the combination of maternal supplementation and BM with HMF. In this study, infants receiving HMF with BM showed the highest growth velocity with the shortest hospital stay before discharge. In this group, infants were already receiving an adequate BM intake of 150-180 ml/kg/day prior to participation in the study. This meant that the HMF group consisted of more stable preterm infants compared to the rest of the supplementated groups. However, a large proportion of participants in the maternal supplementation group also showed adequate to good growth velocity. The researcher recommends the implementation of maternal supplementation only, as standard of care for all hospitalised lactating women. Furthermore, timeous addition of HMF to expressed BM is necessary for infants with growth velocities <15 g/kg/day. This may save costs to the hospital as the use of HMF allowed for better weight gain and earlier discharge.
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- Date Issued: 2018
Evaluating metabolism-induced toxicity using a non-hepatic cell line
- Authors: Weyers, Carli
- Date: 2018
- Subjects: Cytochrome P-450 , Drugs Metabolism , Drugs Design
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/61950 , vital:28087
- Description: The drug discovery pipeline is a complicated process taking roughly 15 years to complete, costing in excess of $1 billion per new chemical entity. It has been estimated that for every 100, 000 promising hit or lead compounds, only one will make it onto the market due to numerous drug candidates being discarded because of many complications. One such complication is metabolism-induced toxicity. Accordingly, an early understanding of the metabolism of any new chemical entity is becoming an integral part of the pipeline. In order to explore this, various methods have been developed including in silico and in vitro techniques. One such method involves performing cell viability assays on human liver cancer cell lines, which overexpress specific metabolic cytochrome P450 enzymes. If a toxic metabolite is produced it would result in reduced cell viability of the transformed cell line in comparison to a control. Since the liver is the primary site of metabolism in the human body, we were curious as to the extent to which background metabolism may play a role in the degree to which toxic metabolites would be produced in these cell lines. The aim of this project, therefore, was to establish if a non-hepatic cell-based system which overexpresses CYP3A4 could be used to detect the metabolism and any subsequent toxicity of compounds which have been reported to be substrates of the CYP450 enzyme. The HEK293 cell line was stably transfected with a plasmid vector for human CYP3A4 to create a model overexpression system for our metabolism studies. The activity of the enzyme was confirmed using the substrate, 7-benzyloxy-4-trifluoromethyl-coumarin. Subsequently, cytotoxicity testing was done on four known pharmaceuticals reported to generate toxic metabolites in hepatic cell-based assays. In silico metabolic predictions on the four known compounds were performed and compared to the results of published literature. Finally, the metabolism of one compound was studied using a combination of high performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) in order to detect predicted metabolites. We observed no change in cellular toxicity nor did we detect the formation of metabolites, even though the overexpressed CYP3A4 enzyme was active. The results suggest that caution should be taken when interpreting the results of cell-based metabolism studies, and background metabolism may play a significant role in the data. , Thesis (MSc) -- Faculty of Pharmacy, Pharmacy, 2018
- Full Text:
- Date Issued: 2018
Use of a non-hepatic cell line highlights limitations associated with cell-based assessment of metabolically induced toxicity:
- Authors: Weyers, Carli , Dingle, Laura M K , Wilhelmi, Brendan S , Edkins, Adrienne L , Veale, Clinton G
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/160290 , vital:40431 , DOI: 10.1080/01480545.2019.1585869
- Description: Metabolically induced drug-toxicity is a major cause of drug failure late in drug optimization phases. Accordingly, in vitro metabolic profiling of compounds is being introduced at earlier stages of the drug discovery pipeline. An increasingly common method to obtain these profiles is through overexpression of key CYP450 metabolic enzymes in immortalized liver cells, to generate competent hepatocyte surrogates. Enhanced cytotoxicity is presumed to be due to toxic metabolite production via the overexpressed enzyme. However, metabolically induced toxicity is a complex multi-parameter phenomenon and the potential background contribution to metabolism arising from the use of liver cells which endogenously express CYP450 isoforms is consistently overlooked. In this study, we sought to reduce the potential background interference by applying this methodology in kidney-derived HEK293 cells which lack endogenous CYP450 expression.
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- Date Issued: 2020
HIV/AIDS and other household shocks as catalysts of local commercialization of non-timber forest products in Southern Africa
- Authors: Weyer, Dylan J , Shackleton, Charlie M , Adam, Y O
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/398223 , vital:69385 , xlink:href="https://doi.org/10.1111/dpr.12261"
- Description: Local trade in non-timber forest products (NTFPs) is increasing globally, yet the causes have been little studied. We examine household shock as a driver of NTFP trade in five southern African countries, with an emphasis on HIV/AIDS-related illness and death. Over the past two years, 95% of trader households experienced at least one shock, with family illness and death recorded for 68% and 42% of households, respectively. Almost 40% had entered the trade because of HIV/AIDS-related shocks. Additional shocks included natural disasters, crop pests or failure and livestock loss. The sale of NTFPs was the third most common coping strategy, after kinship and agricultural adjustments. Coping strategies differed between sites and type of shock.
- Full Text:
- Date Issued: 2018