COSATU Executive committee press statement - 20 AUGUST 1998
- Authors: COSATU
- Date: Aug 1998
- Subjects: COSATU
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/109688 , vital:33169
- Description: The Executive Committee met in its normal session on 18 - 19 August 1998. It received reports on a range of socio-economic and political issues. As is always the case, discussions were conducted in a true tradition of the federation - comradeship, frankness, robust and constructive. A number of decisions were taken by the meeting, some of which are contained in this statement. The meeting received a report on meetings held with Old Mutual and Sanlam respectively. The meeting reaffirmed COSATU’s opposition to demutualisation on political and economic grounds and regretted the fact that the portfolio committee had gone ahead to finalise the bills dealing with demutualisation inspite of being informed about discussions currently taking place with the two mutual companies. We remain of the view that it would help the parliamentary process had this process been allowed to proceed to its final conclusion.
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- Date Issued: Aug 1998
Cytotoxicity of triterpenoids from Clerodendrum glabrum against triple negative breast cancer cells in vitro:
- Authors: Teclegeorgish, Zecarias W , Mokgalaka, Ntebogeng S , Vukea, Nyeleti , de la Mare, Jo-Anne , Tembu, Vuyelwa J
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/161511 , vital:40634 , https://doi.org/10.1016/j.sajb.2020.07.009
- Description: Clerodendrum glabrum is an indigenous medicinal plant that is used to treat cough, cold, sore throat and chest complaints. The stem bark of Clerodendrum glabrum afforded four tritepenoids namely, 3β-olean-12-en-3-yl palmitate (β-amyrin palmitate), (1), 3β hydroxy 5-glutinene (glutinol), (2), 3β-lup-20(29)-en-3-palmitate (Lupeol-3-palmitate), (3), 3β-lup-20(29)-en-3-ol (lupeol) (4) and one common phytosterol (stigmasterol) (5). The structures were established on the basis of their spectroscopic analysis. The compounds were screened for cytotoxicity against the HCC70 triple negative breast cancer (TNBC), MCF-7 hormone receptor positive breast cancer and MCF-12A non-cancerous mammary epithelial cell lines.
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- Date Issued: 2020
Debunking the myth of lack of vocabulary for teaching content knowledge in primary schools: exploring terminology for science in Ekegusii of Kenya
- Authors: Mose, Peter
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150095 , vital:38939 , DOI: 10.1080/02572117.2020.1733827
- Description: The language-in-education policy to teach in mother tongues at lower primary level is not adhered to by classroom teachers in Kenya due to, among other reasons, lack of content terminology. The purpose of this study was to demonstrate that mother tongues can be used to teach science up to the end of grade three, considering the nature of topics for this level and other extra-classroom realities. Our research objectives were to examine the nature and content of science topics and sub-topics from grade one to grade three; examine conceptual and technical terms in grade one to grade three science textbooks; describe the Ekegusii equivalents of these terms; and explain the feasibility of teaching science in Ekegusii up to the end of grade three.
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- Date Issued: 2020
Deriving an optimal threshold of waist circumference for detecting cardiometabolic risk in sub-Saharan Africa
- Authors: Longo–Mbenza, Benjamin , K Ekoru, GAV Murphy, EH Young, H Delisle, CS Jerome , F Assah, JPD Nzambi, JBK On'Kin , F Buntix, MC Muyer, DL Christensen, CS Wesseh, A Sabir, C Okafor, ID Gezawa, F Puepet, O Enang, T Raimi, E Ohwovoriole, OO Oladapo, P Bovet, W Mollentze, N Unwin, WK Gray, R Walker K Agoudavi, S Siziya, J Chifamba, M Njelekela, CM Fourie, S Kruger, AE Schutte, C Walsh, D Gareta, A Kamali, J Seeley, SA Norris NJ Crowther, D Pillay, P Kaleebu, AA Motala and MS Sandhu on behalf of the African Partnership for Chronic Disease Research (APCDR)
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/5389 , vital:44560 , https://www.nature.com/articles/ijo2017240
- Description: BACKGROUND: Waist circumference (WC) thresholds derived from western populations continue to be used in sub-Saharan Africa (SSA) despite increasing evidence of ethnic variation in the association between adiposity and cardiometabolic disease and availability of data from African populations. We aimed to derive a SSA-specific optimal WC cut-point for identifying individuals at increased cardiometabolic risk. METHODS: We used individual level cross-sectional data on 24 181 participants aged ⩾15 years from 17 studies conducted between 1990 and 2014 in eight countries in SSA. Receiver operating characteristic curves were used to derive optimal WC cutpoints for detecting the presence of at least two components of metabolic syndrome (MS), excluding WC. RESULTS: The optimal WC cut-point was 81.2 cm (95% CI 78.5–83.8 cm) and 81.0 cm (95% CI 79.2–82.8 cm) for men and women, respectively, with comparable accuracy in men and women. Sensitivity was higher in women (64%, 95% CI 63–65) than in men (53%, 95% CI 51–55), and increased with the prevalence of obesity. Having WC above the derived cut-point was associated with a twofold probability of having at least two components of MS (age-adjusted odds ratio 2.6, 95% CI 2.4–2.9, for men and 2.2, 95% CI 2.0–2.3, for women). CONCLUSION: The optimal WC cut-point for identifying men at increased cardiometabolic risk is lower (⩾81.2 cm) than current guidelines (⩾94.0 cm) recommend, and similar to that in women in SSA. Prospective studies are needed to confirm these cut-points based on cardiometabolic outcomes.
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- Date Issued: 2018
Descriptive Chemistry: PAC 113F
- Authors: Hasheni, T , Mrwebi, M , Tichagwa, L , Ajibade, A P
- Date: 2008-07
- Language: English
- Type: Examination paper
- Identifier: vital:17825 , http://hdl.handle.net/10353/d1010378
- Description: Descriptive Chemistry: PAC 113F, supplementary degree examination July 2008.
- Full Text: false
- Date Issued: 2008-07
Determination of the optimal water temperature for the culture of juvenile dusky kob Argyrosomus japonicus Temminck and Schlegel 1843:
- Authors: Collett, Paul D , Vine, Niall G , Kaiser, Horst , Baxter, Jeremy
- Date: 2008
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142804 , vital:38118 , DOI: 10.1111/j.1365-2109.2008.01960.x
- Description: The effects of temperature on growth, food conversion ratio (FCR) and feeding intensity of juvenile dusky kob Argyrosomus japonicus (23.7±2.6 g fish−1) were assessed over the temperature range 17.5–28.5°C in a 42 day growth trial. Growth increased with increasing temperature up to an optimum after which it declined. Specific growth rates were 2.05% and 1.2% day−1 for the fastest (25.3 °C) and the slowest (17.5 °C) treatments respectively. Food conversion ratio peaked at a lower temperature than growth. Optimal (0.72 kg kg gain−1) and least efficient (1.40 kg kg gain−1) FCR were found at 21.7 and 17.5°C respectively. Feeding intensity was linearly related to temperature within the range of 17.5–28.5°C. These results corresponded to the thermal preference (25–26.4°C) and natural temperature distribution (12–28°C) of South African dusky kob. Determination of the temperature range that does not limit growth is a prerequisite to assess the relationship between growth and environmental variables such as light intensity, feeding regime and stocking density. Consequently, experiments to determine the effects of these environmental variables on growth and aquaculture potential of dusky kob should be conducted at 24–26°C.
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- Date Issued: 2008
Diet of the endemic bivalve Solen cylindraceus inferred from stable isotope analysis in the Kariega Estuary, South Africa
- Authors: Nel, Holly A , Froneman, P William
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/67933 , vital:29170 , https://doi.org/10.1080/13235818.2016.1175917
- Description: Publisher version , Sedentary filter-feeders such as the razor clam (Solen cylindraceus) are believed to indiscriminately exploit a carbon source derived from particulate organic matter (POM). POM demonstrates a high degree of spatial and temporal variability in composition, which may result in intraspecific dietary variation. This study aimed to investigate seasonal ontogenetic shifts in the feeding ecology of S. cylindraceus using dual stable isotopic (δ13C and δ15N) analyses in the oligotrophic temperate permanently open Kariega Estuary, South Africa. Mixing model results demonstrate that the different size classes of S. cylindraceus had a diet comprised mainly of POM. However, size grouping did have a significant effect on carbon and nitrogen signatures. Specifically, during winter, carbon isotopic signatures became more depleted with a decrease in size, while both winter and summer δ15N values became more nitrogen enriched with an increase in size. The observed trend in the ratios can likely be ascribed to the hydrodynamics of the system. Data from this study suggest that there may be some degree of variation among the different size cohorts, although this needs further investigation.
- Full Text: false
- Date Issued: 2016
Diet of two Antarctic dragonfish (Pisces: Bathydraconidae) from the Indian sector of the Southern Ocean
- Authors: Pakhomov, E A
- Date: 1998
- Subjects: Antarctica Bathydraconidae
- Language: English
- Type: Article
- Identifier: vital:6943 , http://hdl.handle.net/10962/d1011970 , http://dx.doi.org/10.1017/S095410209800008X
- Description: The diet of Cygnodraco mawsoni Waite 1916 and Gymnodraco acuticeps Boulenger 1902 (Pisces: Bathydraconidae) was studied in the Cooperation and Cosmonaut seas in the depth range 200–400 m during the summer 1988. Stomach content analysis showed that both species are piscivorous predators but with different feeding habits. Cygnodraco mawsoni fed mostly on young notothenioid fish, regularly complementing these with pelagic, Euphausia superba, and benthic crustaceans, such as amphipod gammarids and mysids. In contrast, G. acuticeps relied mostly on mesopelagic fish of the family Myctophidae. Although C. mawsoni and G. acuticeps occupy similar depths in the Cosmonaut Sea, different feeding habits appear to limit the probability of interspecific competition for food.
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- Date Issued: 1998
Disaster management policy options to address the sanitation challenges in South Africa
- Authors: Hoossein, Shafick , Tandlich, Roman , Whittington-Jones, Kevin J , Laubscher, Richard K , Madikizela, Phindile , Zuma, Bongumusa M
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/75938 , vital:30485 , https://www.neha.org/node/28591
- Description: The current population of South Africa has been migrating into informal urban settlements that lack adequate sanitation service delivery, caused at least in part by the lack of the necessary skills in the local government sector and the lack of buy in from the community into the provided sanitation facilities. The authors report results of policy research into the relevant disaster management options that could be applied to improve the sanitation service delivery in South Africa. The best policy option was identified as the draft Disaster Management Regulations: Disaster Management. Local government can use these tools through the formation of the volunteer units from the nongovernmental organization sector, the business community, and from among the end users of sanitation facilities. Formation of the volunteer unit should follow the principles of cooperative governance and participatory approach to disaster management. Implementation should be facilitated through the adoption of locally specific municipal by laws.
- Full Text: false
- Date Issued: 2016
Distributed Web Computing: CSC 523
- Authors: Thinyane, M , Vogts, D
- Date: 2010-11
- Language: English
- Type: Examination paper
- Identifier: vital:17786 , http://hdl.handle.net/10353/d1010326
- Description: Distributed Web Computing: CSC 523, honours examination November 2010.
- Full Text: false
- Date Issued: 2010-11
Education Studies 2(A): ECA 421
- Authors: Vye, Z , Macanda, M A A , Sao, L , Madubedube, M , Jordaan, D C
- Date: 2010-01
- Subjects: Education
- Language: English
- Type: Examination paper
- Identifier: vital:17284 , http://hdl.handle.net/10353/d1010030
- Description: Examination on Education Studies 2(A): ECA 421, January 2010.
- Full Text: false
- Date Issued: 2010-01
Education: EDL 222
- Authors: Shaughnessy, C , Botha, E
- Date: 2010-10
- Language: English
- Type: Examination paper
- Identifier: vital:18330 , http://hdl.handle.net/10353/d1011456
- Description: Education: EDL 222, final examination November 2010.
- Full Text: false
- Date Issued: 2010-10
Effect of concentration and degree of saturation of topical fluocinonide formulations on in vitro membrane transport and in vivo availability on human skin
- Authors: Schwarb, Fabian P , Imanidis, Georgios , Smith, Eric W , Haigh, John M , Surber, Christian
- Date: 1999
- Language: English
- Type: text , Article
- Identifier: vital:6425 , http://hdl.handle.net/10962/d1006560
- Description: Purpose. The thermodynamic acitvity of drugs in topical vehicles is considered to significantly influence topical delivery. In vitro diffusion across a synthetic membrane was shown to be correlated to the degree of saturation of the drug in the applied vehicle and therefore offers a potential for increased topical drug delivery. Fluocinonide a topical corticosteroid, was chosen as a model compound to investigate in vitro and in vivo availability from formulations with different degrees of saturation. Methods. Sub-, as well as, supersaturated drug solutions were prepared using PVP as an antinucleant agent. In vitro membrane diffusion experiments across silicone membrane and in vivo pharmacodynamic activity assessments, using the human skin blanching assay, were carried out. Results. Over the concentration range studied, the in vitro membrane transport of fluocinonide was proportional to the degree of saturation of the respective formulations. The in vivo pharmacodynamic response in the human skin blanching assay was related to the concentration of the drug in the vehicle irrespective of the degree of saturation. Conclusions. From the membrane permeation experiment it can be concluded, that the drug flux might be increased supra-proportionally with increasing donor concentration, drug (super-)saturation (proportional), beyond what would be anticipated based on ideal donor concentration and partition coefficient considerations only. These findings could not be confirmed in the in vivo investigation, probably due to additional vehicle effects (e.g., enhancement, irritation, drug binding) which have to be expected and could have altered the integrity of the stratum corneum and therewith topical bioavailability of the drug.
- Full Text: false
- Date Issued: 1999
Effect of pictograms on readability of patient information materials:
- Authors: Mansoor, Leila E , Dowse, Roslind
- Date: 2003
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/157003 , vital:40078 , https://0-doi.org.wam.seals.ac.za/10.1345/aph.1C449
- Description: To design, develop, and evaluate a simple, understandable medicine label and patient information leaflet (PIL) for nystatin suspension, and to assess the effect of incorporating pictograms on understanding in low-literate participants.
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- Date Issued: 2003
Effects of an eight-week stepladder exercise protocol on lower limb muscular strength of apparently healthy young adults
- Authors: Olagbegi, Oladapo M , Adegoke, Babatunde O , Christie, Candice J , Bolarinde, Olufemi S , Jegede, Joseph A
- Date: 2017
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59974 , vital:27716 , doi: 10.1515/humo-2017-0026
- Description: Purpose. backward descent of stairs is associated with improved muscle strength and reduced joint stress, but the effect of backward ascent of stairs on lower limb muscle strength has not been reported. This study compared the effects of forward and backward stair climbing on lower limb muscle strength in apparently healthy young adults. Methods. The total of 31 young volunteers were allocated to either forward or backward stair climbing group (n = 16 and 15, respectively). Dynamic quadriceps and hamstring muscle strength was assessed in addition to thigh girth at baseline and at weeks 4 and 8 with the use of the repetitive maximum method and tape measure, respectively. Results. Between baseline and week 8, muscular strength in both groups (quadriceps: 14.4 ± 3.6 to 16.4 ± 3.4 kg; 14.0 ± 2.9 to 15.3 ± 2.7 kg; hamstring: 12.2 ± 3.2 to 13.4 ± 3.2; 11.7 ± 2.5 to 12.9 ± 2.7 kg) increased significantly (p<0.05) while the increase in thigh girth was not significant (p>0.05). The groups were comparable in all three measures post intervention. Conclusions. Forward and backward stair climbing protocols are effective for improving the dynamic strength of the hamstring and quadriceps muscles of apparently healthy young adults. Thus, either protocol could be used for the improvement of lower limbs dynamic muscle strength.
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- Date Issued: 2017
Elucidation of the complex Baylis-Hillman reaction of 3-methoxy-2-nitrobenzaldehyde with methyl vinyl ketone
- Authors: Idahosa, Kenudi C , Molefe, Duduzile M , Pakade, Vusumzi E , Brown, Michael E
- Date: 2011
- Language: English
- Type: Article
- Identifier: vital:6574 , http://hdl.handle.net/10962/d1004137
- Description: DABCO-catalyzed reaction of 3-methoxy-2-nitrobenzaldehyde with methyl vinyl ketone (MVK) affords a mixture of products, comprising the ‘normal’ Baylis-Hillman adduct, theMVKdimer and a pair of diastereomeric bis-(MVK)Baylis-Hillman adducts. 1HNMRspectroscopy-based kinetic studies have provided clear insights into the competing pathways and product distribution in this complex reaction.
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- Date Issued: 2011
Eskom 1989 Negotiations report back
- Authors: NUM
- Date: 1989
- Subjects: NUM
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/134893 , vital:37215
- Description: Eskom has paid wage increases to salaried staff backdated to 1 April 1989. The NUM has NOT agreed with these increases because they are too low. We are not allowed to go on strike at Eskom - we have to get an arbitrator to decide if the increases must be bigger.
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- Date Issued: 1989
Eskom wage negotiations for general workers 1989
- Authors: NUM
- Date: 1989
- Subjects: NUM
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/134916 , vital:37217
- Description: Eskom started the 1989 wage negotiations with an offer of 7% on average. They said this offer is ail they need to make to keep their relative position in the labour market. we believe that the Eskom offer is contrary to the substance and spirit of Arbitration Award which forced Eskom, in 1988, to grant a 14,8% average increase in place of the 10% average increase Eskom implemented unilaterally m July last year. Dr Dry, the Eskom personnel manager, read out from an NUM pamphlet issued after the arbitrators raised the wages. He read out this one sentence. Today, through unity, the minimum wage rates as Eskom are amongst the highest in the country for workers living in compounds.
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- Date Issued: 1989
Evaluation of the kinetics and mechanism of drug release from Econazole nitrate nanosponge loaded Carbapol Hydrogel
- Authors: Sharma, Renuka , Walker, Roderick B , Pathak, Kamla
- Date: 2011
- Language: English
- Type: text , Article
- Identifier: vital:6437 , http://hdl.handle.net/10962/d1006614
- Description: The objective of this study was to investigate the mechanism of release of econazole nitrate (EN) nanosponges loaded hydrogel and to compare it with EN hydrogel so as to develop an extended release topical drug delivery system of EN. Nanosponges of EN were prepared using ethyl cellulose and PVA by emulsion solvent evaporation method. On the basis of pharmacotechnical evaluation nanosponges with least particle size of 230.1 nm and good rheological properties were formulated as hydrogel (F1 – F7). In vitro drug release data of EN nanosponges loaded hydrogels in phosphate buffer pH 6.8 and 7.4 when analysed by GraphPad Prism software version 4.0 San Diego, USA best fitted the Makoid-2 Banakar model (R value greater than 0.98). The Korsmeyer-Peppas release exponent (n) ranged between 0.331 – 0.418, which confirmed diffusion as the principle mechanism of drug release. The release mechanism was further confirmed by calculating the ratio of exponents A/B ratio derived from the Kopcha model.
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- Date Issued: 2011
Evidence for Archaean lamprophyre from the Kaapvaal Craton, South Africa
- Authors: Prevec, S A , Anhaeusser, C R , Poujol, M
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6739 , http://hdl.handle.net/10962/d1007555
- Description: A suite of mafic dykes occurs as a late component in a wellcharacterized trondhjemite–tonalite–diorite–granodiorite assemblage in the Johannesburg Dome of the central Kaapvaal Craton, southern Africa. The dykes have been subdivided into two sets, based on their orientation, and major and trace element geochemistry. Set 1 dykes are characterized by elevated SiO2, Al2O3 and TiO2, and particularly by enriched LILE and HSFE (e.g. Zr > 200 ppm, Nb > 20 ppm, Ba > 300 ppm), higher than in any of the accompanying felsic rocks. REE and trace element values for Set 1 dykes are similar to those for calc-alkaline lamprophyres. The Set 2 dykes have similar trace element distributions, but are significantly less enriched in general, and are broadly tholeiitic in composition, with enriched MgO (>11 wt. percentage) indicative of an olivine–phyric tholeiitic basaltic protolith. Field relationships and available U–Pb zircon geochronology indicate that the dykes are contemporaneous with components of the trondhjemitic host rocks, and with late granodiorites. The geochemical, geochronological and field petrological setting indicates partial melting of basaltic and eclogitic lithosphere at c. 3120 Myr ago in the basal Kaapvaal Craton, and subsequent emplacement into pre-existing c. 3430 Myr tonalitic to dioritic crust.
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- Date Issued: 2004