Synthesis of molecularly imprinted polymer for selective solid-phase extraction of Salbutamol from urine samples

Title: Synthesis of molecularly imprinted polymer for selective solid-phase extraction of Salbutamol from urine samples
Creator: Mohammadi, Ali
Creator: Alizadeh, Taher
Creator: Dinarvand, Rassoul
Creator: Ganjali, Mohammed M
Creator: Walker, Roderick B
Date Issued: 2009
Date: 2009
Type: Article
Identifier: vital:6410
Identifier: http://hdl.handle.net/10962/d1006496
Description: A highly selective methacrylic based molecularly imprinted polymer (MIP) was synthesized and applied for the separation and the pre-concentration of salbutamol in urine samples. Spectrophotometric determination of salbutamol was achieved using 2,6-dichloroquinone chlorimide as colorimetric reagent. The detection limit of the method was ca. 13 ng/mL in urine after pre-concentration of the samples by MIP-SPE andanalysis with an optimized and sensitive spectrophotometric method. The linear dynamic range for salbutamol determination in urine was 0.04-0.75 μg mL-1. The recovery for the affinity based solid-phase extraction (SPE) with the MIP was more than 96 %.
Format: 6 pages
Format: pdf
Language: English
Relation: Mohammadi, A. and Alizadeh, T. and Dinarvand, R. and Ganjali, M.R. and Walker, R.B. (2009) Synthesis of molecularly imprinted polymer for selective solid-phase extraction of Salbutamol from urine samples. Asian Journal of Chemistry, 21 (4). pp. 2875-2880.

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Walker, Roderick Bryan (Prof)

RU Department of Pharmacy

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