A “place in which to cry”: the place for race and a home for shame in Zoë Wicomb's Playing in the Light
- Authors: Dass, Minesh
- Date: 2011
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142588 , vital:38093 , DOI: 10.1080/1013929X.2011.602910
- Description: In Zoë Wicomb's Playing in the Light, the main character's troubled sense of identity (brought about by her parents' shameful decision to ‘play white’) is viscerally symbolised by her discomfort in her own and others' homes. In her Cape Town apartment she has nightmares about other houses. Her visits to her family home, where her elderly father lives alone, are similarly burdened by presences and memories she finds unwelcoming. And, her extended vacation to the UK, once she has discovered her family's secret, is a choice of “a place in which to cry” (Wicomb 2006: 191).
- Full Text:
- Date Issued: 2011
- Authors: Dass, Minesh
- Date: 2011
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142588 , vital:38093 , DOI: 10.1080/1013929X.2011.602910
- Description: In Zoë Wicomb's Playing in the Light, the main character's troubled sense of identity (brought about by her parents' shameful decision to ‘play white’) is viscerally symbolised by her discomfort in her own and others' homes. In her Cape Town apartment she has nightmares about other houses. Her visits to her family home, where her elderly father lives alone, are similarly burdened by presences and memories she finds unwelcoming. And, her extended vacation to the UK, once she has discovered her family's secret, is a choice of “a place in which to cry” (Wicomb 2006: 191).
- Full Text:
- Date Issued: 2011
Rhodes University Library Annual Report 2010: Library Director’s Review
- Authors: Thomas, G M E
- Date: 2011
- Language: English
- Type: Text
- Identifier: vital:7943 , http://hdl.handle.net/10962/d1011890
- Description: [From the Introduction] 2010 was a momentous year for the Library, and for the University, with the new section of the Library being opened to users on 29 January and culminating in the official opening of the building on 4 November. This brought to conclusion the Library Building Project, an extension and refurbishment of the existing building, with building work beginning on 8 September 2008.
- Full Text:
- Date Issued: 2011
- Authors: Thomas, G M E
- Date: 2011
- Language: English
- Type: Text
- Identifier: vital:7943 , http://hdl.handle.net/10962/d1011890
- Description: [From the Introduction] 2010 was a momentous year for the Library, and for the University, with the new section of the Library being opened to users on 29 January and culminating in the official opening of the building on 4 November. This brought to conclusion the Library Building Project, an extension and refurbishment of the existing building, with building work beginning on 8 September 2008.
- Full Text:
- Date Issued: 2011
Study of protein complexes via homology modeling, applied to cysteine proteases and their protein inhibitors:
- Tastan Bishop, Özlem, Kroon, Matthys
- Authors: Tastan Bishop, Özlem , Kroon, Matthys
- Date: 2011
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148070 , vital:38707 , DOI: 10.1007/s00894-011-0990-y
- Description: This paper develops and evaluates large-scale calculation of 3D structures of protein complexes by homology modeling as a promising new approach for protein docking. The complexes investigated were papain-like cysteine proteases and their protein inhibitors, which play numerous roles in human and parasitic metabolisms. The structural modeling was performed in two parts. For the first part (evaluation set), nine crystal structure complexes were selected, 1325 homology models of known complexes were rebuilt by various templates including hybrids, allowing an analysis of the factors influencing the accuracy of the models. The important considerations for modeling the interface were protease coverage and inhibitor sequence identity. In the second part (study set), the findings of the evaluation set were used to select appropriate templates to model novel cysteine protease-inhibitor complexes from human and malaria parasites Plasmodium falciparum and Plasmodium vivax. The energy scores, considering the evaluation set, indicate that the models are of high accuracy.
- Full Text:
- Date Issued: 2011
- Authors: Tastan Bishop, Özlem , Kroon, Matthys
- Date: 2011
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148070 , vital:38707 , DOI: 10.1007/s00894-011-0990-y
- Description: This paper develops and evaluates large-scale calculation of 3D structures of protein complexes by homology modeling as a promising new approach for protein docking. The complexes investigated were papain-like cysteine proteases and their protein inhibitors, which play numerous roles in human and parasitic metabolisms. The structural modeling was performed in two parts. For the first part (evaluation set), nine crystal structure complexes were selected, 1325 homology models of known complexes were rebuilt by various templates including hybrids, allowing an analysis of the factors influencing the accuracy of the models. The important considerations for modeling the interface were protease coverage and inhibitor sequence identity. In the second part (study set), the findings of the evaluation set were used to select appropriate templates to model novel cysteine protease-inhibitor complexes from human and malaria parasites Plasmodium falciparum and Plasmodium vivax. The energy scores, considering the evaluation set, indicate that the models are of high accuracy.
- Full Text:
- Date Issued: 2011
- «
- ‹
- 1
- ›
- »