Assessment of topical corticosteroid preparations: the human skin-blanching assay

Title: Assessment of topical corticosteroid preparations: the human skin-blanching assay
Creator: Haigh, John M
Creator: Kanfer, Isadore
Date Issued: 1984
Date: 1984
Type: text
Type: Article
Identifier: vital:6374
Identifier: http://hdl.handle.net/10962/d1006284
Description: (From the introduction) Since the introduction of topical corticosteroid formulations, their use has become widespread, being prescribed for a large variety of dermatological conditions. This widespread use has created a need for a reliable method of assessing the various dosage forms of these compounds. Clinical trials are laborious, costly and difficult to mount as well as being impractical for the screening of large numbers of drugs. Patients suffering from dermatological complaints are not ideal subjects for the testing of topical corticosteroid preparations as it is difficult to obtain standardized lesions which are necessary for the comparison of results between patients (Baker and Sattar, 1968). For these reasons a number of methods have been developed for the screening of novel corticosteroids and testing of topical corticosteroid formulations.
Format: 18 pages
Format: pdf
Language: English
Relation: Haigh, J.M. and Kanfer, I. (1984) Assessment of topical corticosteroid preparations: the human skin-blanching assay. International Journal of Pharmaceutics, 19 (3). pp. 245-262. Available: http://dx.doi.org/10.1016/0378-5173(84)90055-3

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Kanfer, Isadore (Prof)

RU Department of Pharmacy

Haigh, JM (Prof)

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