Studies on the Zoarcidae, (Teleostei: Perciformes) of the Southern hemisphere. III. The Southwestern Pacific
- Anderson, M Eric, J.L.B. Smith Institute of Ichthyology
- Authors: Anderson, M Eric , J.L.B. Smith Institute of Ichthyology
- Date: 1990-07
- Subjects: Zoarcidae , Fishes -- South Africa
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/70348 , vital:29647 , Margaret Smith Library (South African Institute for Aquatic Biodiversity (SAIAB)) Periodicals Margaret Smith Library (South African Institute for Aquatic Biodiversity (SAIAB))
- Description: Online version of original print edition of the Special Publication of the J.L.B. Smith Institute of Ichthyology; No. 50 , The eelpout fauna of the southwestern Pacific presently includes 6 species, one of which, Pachycara garricki, is described as new. Full species accounts and illustrations are also provided for Melanostigma inexpectatum, Ophthalmolycus campbellensis, and Lycenchelys maoriorum, known previously only from the meager type series. Two species, Melanostigma gelatinosum, and M. vitiazi were redescribed in the first part of this series, but expanded diagnoses are provided here. Lycenchelys maoriomm and O. campbellensis are expected to be endemic to the New Zealand Plateau and perhaps Lord Howe Rise.
- Full Text:
- Date Issued: 1990-07
- Authors: Anderson, M Eric , J.L.B. Smith Institute of Ichthyology
- Date: 1990-07
- Subjects: Zoarcidae , Fishes -- South Africa
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/70348 , vital:29647 , Margaret Smith Library (South African Institute for Aquatic Biodiversity (SAIAB)) Periodicals Margaret Smith Library (South African Institute for Aquatic Biodiversity (SAIAB))
- Description: Online version of original print edition of the Special Publication of the J.L.B. Smith Institute of Ichthyology; No. 50 , The eelpout fauna of the southwestern Pacific presently includes 6 species, one of which, Pachycara garricki, is described as new. Full species accounts and illustrations are also provided for Melanostigma inexpectatum, Ophthalmolycus campbellensis, and Lycenchelys maoriorum, known previously only from the meager type series. Two species, Melanostigma gelatinosum, and M. vitiazi were redescribed in the first part of this series, but expanded diagnoses are provided here. Lycenchelys maoriomm and O. campbellensis are expected to be endemic to the New Zealand Plateau and perhaps Lord Howe Rise.
- Full Text:
- Date Issued: 1990-07
Secrets, lies and redemption:
- Boshoff, Priscilla A, Prinsloo, Jeanne
- Authors: Boshoff, Priscilla A , Prinsloo, Jeanne
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143381 , vital:38241 , DOI: 10.1080/00020184.2017.1285671
- Description: Confession is a central disciplining technology deployed in the second series of Intersexions, a popular South African TV series that seeks to change sexual and social behaviours that contribute to the risk of HIV infection. The article considers the ‘edu’ part of this edutainment programme, specifically with the nature of the lessons and with the form of ‘disciplining’ the narratives presuppose for gendered and sexual subjects. Central to this critical and constructivist exploration of the gender relationships that are validated and expurgated are Foucault’s notions of discourse and confession as a technology of self. We argue that the series presents a range of different gendered and sexual subjectivities but implicitly endorses a modern subjectivity and transformation at the level of the individual.
- Full Text:
- Date Issued: 2017
- Authors: Boshoff, Priscilla A , Prinsloo, Jeanne
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143381 , vital:38241 , DOI: 10.1080/00020184.2017.1285671
- Description: Confession is a central disciplining technology deployed in the second series of Intersexions, a popular South African TV series that seeks to change sexual and social behaviours that contribute to the risk of HIV infection. The article considers the ‘edu’ part of this edutainment programme, specifically with the nature of the lessons and with the form of ‘disciplining’ the narratives presuppose for gendered and sexual subjects. Central to this critical and constructivist exploration of the gender relationships that are validated and expurgated are Foucault’s notions of discourse and confession as a technology of self. We argue that the series presents a range of different gendered and sexual subjectivities but implicitly endorses a modern subjectivity and transformation at the level of the individual.
- Full Text:
- Date Issued: 2017
South African local government bargaining council
- SAMWU
- Authors: SAMWU
- Subjects: SAMWU
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/173941 , vital:42423
- Description: The headings of the clauses in this agreement are for the purpose of convenience and reference only and shall not be used in the interpretation of nor modify nor amplify the terms of this agreement for any clause hereof.
- Full Text:
- Authors: SAMWU
- Subjects: SAMWU
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/173941 , vital:42423
- Description: The headings of the clauses in this agreement are for the purpose of convenience and reference only and shall not be used in the interpretation of nor modify nor amplify the terms of this agreement for any clause hereof.
- Full Text:
New Unity Movement Presidential Address
- Date: 2004-03
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10948/32492 , vital:32118 , Bulk File 7
- Description: Presidential Addresses were delivered at each Annual conference of the New Unity Movement. This collection, though incomplete, has 18 items ranging from 1989 to 2013.
- Full Text: false
- Date Issued: 2004-03
- Date: 2004-03
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10948/32492 , vital:32118 , Bulk File 7
- Description: Presidential Addresses were delivered at each Annual conference of the New Unity Movement. This collection, though incomplete, has 18 items ranging from 1989 to 2013.
- Full Text: false
- Date Issued: 2004-03
New Unity Movement Bulletin
- Date: 2007-04
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10948/31726 , vital:31740 , Bulk File 7
- Description: The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid government.
- Full Text: false
- Date Issued: 2007-04
- Date: 2007-04
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10948/31726 , vital:31740 , Bulk File 7
- Description: The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid government.
- Full Text: false
- Date Issued: 2007-04
Mulch tower treatment system Part I: Overall performance in greywater treatment
- Zuma, Bongumusa M, Tandlich, Roman, Whittington-Jones, Kevin J, Burgess, Jo E
- Authors: Zuma, Bongumusa M , Tandlich, Roman , Whittington-Jones, Kevin J , Burgess, Jo E
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/71537 , vital:29862 , https://doi.org/10.1016/j.desal.2008.03.030
- Description: A mulch tower (MT) system for greywater treatment is introduced in this paper. Materials used to assemble the MT system included mulch, coarse sand, fine and coarse gravel. Limited removal efficiency of the MT system was demonstrated for alkalinity, total hardness, pH, Cl–, PO43–, NH4+, and SO42–, with the estimated cumulative removals ranging from 7 to 12%. Intermediate removal efficiency was observed for chemical oxygen demand (COD), NO3–, and S2– with the estimated cumulative removals ranging from 24 to 28%. The highest removal efficiency was observed for the total suspended solids (TSS) with the estimated cumulative removal equal to 52%. Given the minute residence time in the MT system, the results obtained were promising and justify scale-up studies for potential on-site applications. The MT effluent did not meet hygienic norms with respect to the faecal coliform concentration (FC) and the total coliform concentration (TC), and further effluent treatment is required before any discharge or reuse of the treated greywater. Further research should focus on characterisation of the microbial community of the MT, and the fate of Cl–, PO43–, NH4+, and SO42–.
- Full Text: false
- Date Issued: 2009
- Authors: Zuma, Bongumusa M , Tandlich, Roman , Whittington-Jones, Kevin J , Burgess, Jo E
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/71537 , vital:29862 , https://doi.org/10.1016/j.desal.2008.03.030
- Description: A mulch tower (MT) system for greywater treatment is introduced in this paper. Materials used to assemble the MT system included mulch, coarse sand, fine and coarse gravel. Limited removal efficiency of the MT system was demonstrated for alkalinity, total hardness, pH, Cl–, PO43–, NH4+, and SO42–, with the estimated cumulative removals ranging from 7 to 12%. Intermediate removal efficiency was observed for chemical oxygen demand (COD), NO3–, and S2– with the estimated cumulative removals ranging from 24 to 28%. The highest removal efficiency was observed for the total suspended solids (TSS) with the estimated cumulative removal equal to 52%. Given the minute residence time in the MT system, the results obtained were promising and justify scale-up studies for potential on-site applications. The MT effluent did not meet hygienic norms with respect to the faecal coliform concentration (FC) and the total coliform concentration (TC), and further effluent treatment is required before any discharge or reuse of the treated greywater. Further research should focus on characterisation of the microbial community of the MT, and the fate of Cl–, PO43–, NH4+, and SO42–.
- Full Text: false
- Date Issued: 2009
Does the growth of structure affect our dynamical models of the Universe? The averaging, backreaction, and fitting problems in cosmology
- Clarkson, C, Ellis, G, Larena, Julien, Umeh, O
- Authors: Clarkson, C , Ellis, G , Larena, Julien , Umeh, O
- Date: 2011
- Language: English
- Type: Article
- Identifier: vital:6791 , http://hdl.handle.net/10962/d1006944
- Description: Structure occurs over a vast range of scales in the Universe. Our large-scale cosmological models are coarse-grained representations of what exists, which have much less structure than there really is. An important problem for cosmology is determining the influence the small-scale structure in the Universe has on its large-scale dynamics and observations. Is there a significant, general relativistic, backreaction effect from averaging over structure? One issue is whether the process of smoothing over structure can contribute to an acceleration term and so alter the apparent value of the cosmological constant. If this is not the case, are there other aspects of concordance cosmology that are affected by backreaction effects? Despite much progress, this 'averaging problem' is still unanswered, but it cannot be ignored in an era of precision cosmology, for instance it may affect aspects of baryon acoustic oscillation observations.
- Full Text:
- Date Issued: 2011
- Authors: Clarkson, C , Ellis, G , Larena, Julien , Umeh, O
- Date: 2011
- Language: English
- Type: Article
- Identifier: vital:6791 , http://hdl.handle.net/10962/d1006944
- Description: Structure occurs over a vast range of scales in the Universe. Our large-scale cosmological models are coarse-grained representations of what exists, which have much less structure than there really is. An important problem for cosmology is determining the influence the small-scale structure in the Universe has on its large-scale dynamics and observations. Is there a significant, general relativistic, backreaction effect from averaging over structure? One issue is whether the process of smoothing over structure can contribute to an acceleration term and so alter the apparent value of the cosmological constant. If this is not the case, are there other aspects of concordance cosmology that are affected by backreaction effects? Despite much progress, this 'averaging problem' is still unanswered, but it cannot be ignored in an era of precision cosmology, for instance it may affect aspects of baryon acoustic oscillation observations.
- Full Text:
- Date Issued: 2011
Determining the unbinding events and conserved motions associated with the pyrazinamide release due to resistance mutations of Mycobacterium tuberculosis pyrazinamidase:
- Amamuddy, Olivier S, Musyoka, Thommas M, Boateng, Rita A, Zabo, Sophakama, Tastan Bishop, Özlem
- Authors: Amamuddy, Olivier S , Musyoka, Thommas M , Boateng, Rita A , Zabo, Sophakama , Tastan Bishop, Özlem
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148869 , vital:38781 , https://doi.org/10.1016/j.csbj.2020.05.0099
- Description: Pyrazinamide (PZA) is the only first-line antitubercular drug active against latent Mycobacterium tuberculosis (Mtb). It is activated to pyrazinoic acid by the pncA-encoded pyrazinamidase enzyme (PZase). Despite the emergence of PZA drug resistance, the underlying mechanisms of resistance remain unclear. This study investigated part of these mechanisms by modelling a PZA-bound wild type and 82 mutant PZase structures before applying molecular dynamics (MD) with an accurate Fe2+ cofactor coordination geometry.
- Full Text:
- Date Issued: 2020
- Authors: Amamuddy, Olivier S , Musyoka, Thommas M , Boateng, Rita A , Zabo, Sophakama , Tastan Bishop, Özlem
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148869 , vital:38781 , https://doi.org/10.1016/j.csbj.2020.05.0099
- Description: Pyrazinamide (PZA) is the only first-line antitubercular drug active against latent Mycobacterium tuberculosis (Mtb). It is activated to pyrazinoic acid by the pncA-encoded pyrazinamidase enzyme (PZase). Despite the emergence of PZA drug resistance, the underlying mechanisms of resistance remain unclear. This study investigated part of these mechanisms by modelling a PZA-bound wild type and 82 mutant PZase structures before applying molecular dynamics (MD) with an accurate Fe2+ cofactor coordination geometry.
- Full Text:
- Date Issued: 2020
Connectivity between marine reserves and exploited areas in the philopatric reef fish Chrysoblephus laticeps (Teleostei: Sparidae)
- Teske, Peter R, Forget, F R G, Cowley, Paul D, Von der Heyden, S, Beheregaray, L B
- Authors: Teske, Peter R , Forget, F R G , Cowley, Paul D , Von der Heyden, S , Beheregaray, L B
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6776 , http://hdl.handle.net/10962/d1008086
- Description: "No-take‟ Marine Protected Areas (MPAs) are successful in protecting populations of many exploited fish species, but it is often unclear whether networks of MPAs are adequately spaced to ensure connectivity among reserves, and whether spillover occurs into adjacent exploited areas. Such issues are particularly important in species with low dispersal potential, many of which exist as genetically distinct regional stocks.The roman, Chrysoblephus laticeps, is an overexploited, commercially important fishery species endemic to South Africa. Post-recruits display resident behavior and occupy small home ranges, making C. laticeps a suitable model species to investigate connectivity in marine teleosts with potentially low dispersal ability. We used multilocus data from two types of highly variable genetic markers (mitochondrial DNA control region and microsatellites) to clarify patterns of genetic connectivity and population structure in C. laticeps using samples from two MPAs and several moderately or severely exploited regions. Despite using analytical tools that are sensitive to detect even subtle genetic structure, we found that this species exists as a single, well-mixed stock throughout its core distribution. This finding lends supports to the status of MPAs as an adequate tool for managing overexploited marine teleosts. Even though adult dispersal out of MPAs is limited, the fact that the large adults in these reserves produce exponentially more offspring than their smaller counterparts in exploited areas makes MPAs a rich source of recruits. We nonetheless caution against concluding that the lack of structure identified in C. laticeps and several other southern African teleosts can be considered to be representative of marine teleosts in this region in general. Many such species are represented in more than one marine biogeographic province and may be comprised of regionally-adapted stocks that need to be managed individually.
- Full Text:
- Date Issued: 2010
- Authors: Teske, Peter R , Forget, F R G , Cowley, Paul D , Von der Heyden, S , Beheregaray, L B
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6776 , http://hdl.handle.net/10962/d1008086
- Description: "No-take‟ Marine Protected Areas (MPAs) are successful in protecting populations of many exploited fish species, but it is often unclear whether networks of MPAs are adequately spaced to ensure connectivity among reserves, and whether spillover occurs into adjacent exploited areas. Such issues are particularly important in species with low dispersal potential, many of which exist as genetically distinct regional stocks.The roman, Chrysoblephus laticeps, is an overexploited, commercially important fishery species endemic to South Africa. Post-recruits display resident behavior and occupy small home ranges, making C. laticeps a suitable model species to investigate connectivity in marine teleosts with potentially low dispersal ability. We used multilocus data from two types of highly variable genetic markers (mitochondrial DNA control region and microsatellites) to clarify patterns of genetic connectivity and population structure in C. laticeps using samples from two MPAs and several moderately or severely exploited regions. Despite using analytical tools that are sensitive to detect even subtle genetic structure, we found that this species exists as a single, well-mixed stock throughout its core distribution. This finding lends supports to the status of MPAs as an adequate tool for managing overexploited marine teleosts. Even though adult dispersal out of MPAs is limited, the fact that the large adults in these reserves produce exponentially more offspring than their smaller counterparts in exploited areas makes MPAs a rich source of recruits. We nonetheless caution against concluding that the lack of structure identified in C. laticeps and several other southern African teleosts can be considered to be representative of marine teleosts in this region in general. Many such species are represented in more than one marine biogeographic province and may be comprised of regionally-adapted stocks that need to be managed individually.
- Full Text:
- Date Issued: 2010
A global study of forensically significant calliphorids: implications for identification
- Harvey, M L, Gaudieri, S, Villet, Martin H, Dadour, I R
- Authors: Harvey, M L , Gaudieri, S , Villet, Martin H , Dadour, I R
- Date: 2008
- Language: English
- Type: text , Article
- Identifier: vital:6863 , http://hdl.handle.net/10962/d1011156
- Description: A proliferation of molecular studies of the forensically significant Calliphoridae in the last decade has seen molecule-based identification of immature and damaged specimens become a routine complement to traditional morphological identification as a preliminary to the accurate estimation of post-mortem intervals (PMI), which depends on the use of species-specific developmental data. Published molecular studies have tended to focus on generating data for geographically localised communities of species of importance, which has limited the consideration of intraspecific variation in species of global distribution. This study used phylogenetic analysis to assess the species status of 27 forensically important calliphorid species based on 1167 base pairs of the COI gene of 119 specimens from 22 countries, and confirmed the utility of the COI gene in identifying most species. The species Lucilia cuprina, Chrysomya megacephala, Ch. saffranea, Ch. albifrontalis and Calliphora stygia were unable to be monophyletically resolved based on these data. Identification of phylogenetically young species will require a faster-evolving molecular marker, but most species could be unambiguously characterised by sampling relatively few conspecific individuals if they were from distant localities. Intraspecific geographical variation was observed within Ch. rufifacies and L. cuprina, and is discussed with reference to unrecognised species.
- Full Text:
- Date Issued: 2008
- Authors: Harvey, M L , Gaudieri, S , Villet, Martin H , Dadour, I R
- Date: 2008
- Language: English
- Type: text , Article
- Identifier: vital:6863 , http://hdl.handle.net/10962/d1011156
- Description: A proliferation of molecular studies of the forensically significant Calliphoridae in the last decade has seen molecule-based identification of immature and damaged specimens become a routine complement to traditional morphological identification as a preliminary to the accurate estimation of post-mortem intervals (PMI), which depends on the use of species-specific developmental data. Published molecular studies have tended to focus on generating data for geographically localised communities of species of importance, which has limited the consideration of intraspecific variation in species of global distribution. This study used phylogenetic analysis to assess the species status of 27 forensically important calliphorid species based on 1167 base pairs of the COI gene of 119 specimens from 22 countries, and confirmed the utility of the COI gene in identifying most species. The species Lucilia cuprina, Chrysomya megacephala, Ch. saffranea, Ch. albifrontalis and Calliphora stygia were unable to be monophyletically resolved based on these data. Identification of phylogenetically young species will require a faster-evolving molecular marker, but most species could be unambiguously characterised by sampling relatively few conspecific individuals if they were from distant localities. Intraspecific geographical variation was observed within Ch. rufifacies and L. cuprina, and is discussed with reference to unrecognised species.
- Full Text:
- Date Issued: 2008
Umabatha: global and local
- Authors: Wright, Laurence
- Date: 2004
- Language: English
- Type: text , article
- Identifier: vital:7032 , http://hdl.handle.net/10962/d1007364 , https://doi.org/10.1080/00138390408691324
- Description: preprint , There can be few shows that test the dimensions and pitfalls of 'globalised' theatre as thoroughly as Welcome Msomi's Umabatha. The worldwide success of the show, in box-office terms, can hardly be argued with. And yet, in its very conception, the vehicle is so riven by intrinsic cultural, theatrical, class and 'nationist' tensions that different audiences cannot but reap utterly different experiences, depending on their own cultural and intellectual inheritance.The show is an instance where theatre practice (sometimes) obfuscates political and aesthetic discourse, showing how easily cultures miss each other and fail to connect, and how easily specific historical, geographical and imperial associations are swamped by shallow 'globalised' audience response.
- Full Text:
- Date Issued: 2004
- Authors: Wright, Laurence
- Date: 2004
- Language: English
- Type: text , article
- Identifier: vital:7032 , http://hdl.handle.net/10962/d1007364 , https://doi.org/10.1080/00138390408691324
- Description: preprint , There can be few shows that test the dimensions and pitfalls of 'globalised' theatre as thoroughly as Welcome Msomi's Umabatha. The worldwide success of the show, in box-office terms, can hardly be argued with. And yet, in its very conception, the vehicle is so riven by intrinsic cultural, theatrical, class and 'nationist' tensions that different audiences cannot but reap utterly different experiences, depending on their own cultural and intellectual inheritance.The show is an instance where theatre practice (sometimes) obfuscates political and aesthetic discourse, showing how easily cultures miss each other and fail to connect, and how easily specific historical, geographical and imperial associations are swamped by shallow 'globalised' audience response.
- Full Text:
- Date Issued: 2004
STIP1/HOP regulates the actin cytoskeleton through interactions with actin and changes in actin-binding proteins cofilin and profilin:
- Beckley, Samantha Joy, Hunter, Morgan C, Kituyi, Sarah N, Wingate, Ianthe, Chakraborty, Abantika, Schwarz, Kelly, Makhubu, Matodzi P, Rousseau, Robert P, Ruck, Duncan K, de la Mare, Jo-Anne, Blatch, Gregory L, Edkins, Adrienne L
- Authors: Beckley, Samantha Joy , Hunter, Morgan C , Kituyi, Sarah N , Wingate, Ianthe , Chakraborty, Abantika , Schwarz, Kelly , Makhubu, Matodzi P , Rousseau, Robert P , Ruck, Duncan K , de la Mare, Jo-Anne , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165373 , vital:41238 , https://doi.org/10.3390/ijms21093152
- Description: Cell migration plays a vital role in both health and disease. It is driven by reorganization of the actin cytoskeleton, which is regulated by actin-binding proteins cofilin and profilin. Stress-inducible phosphoprotein 1 (STIP1) is a well-described co-chaperone of the Hsp90 chaperone system, and our findings identify a potential regulatory role of STIP1 in actin dynamics. We show that STIP1 can be isolated in complex with actin and Hsp90 from HEK293T cells and directly interacts with actin in vitro via the C-terminal TPR2AB-DP2 domain of STIP1, potentially due to a region spanning two putative actin-binding motifs. We found that STIP1 could stimulate the in vitro ATPase activity of actin, suggesting a potential role in the modulation of F-actin formation. Interestingly, while STIP1 depletion in HEK293T cells had no major effect on total actin levels, it led to increased nuclear accumulation of actin, disorganization of F-actin structures, and an increase and decrease in cofilin and profilin levels, respectively. This study suggests that STIP1 regulates the cytoskeleton by interacting with actin, or via regulating the ratio of proteins known to affect actin dynamics.
- Full Text:
- Date Issued: 2020
- Authors: Beckley, Samantha Joy , Hunter, Morgan C , Kituyi, Sarah N , Wingate, Ianthe , Chakraborty, Abantika , Schwarz, Kelly , Makhubu, Matodzi P , Rousseau, Robert P , Ruck, Duncan K , de la Mare, Jo-Anne , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165373 , vital:41238 , https://doi.org/10.3390/ijms21093152
- Description: Cell migration plays a vital role in both health and disease. It is driven by reorganization of the actin cytoskeleton, which is regulated by actin-binding proteins cofilin and profilin. Stress-inducible phosphoprotein 1 (STIP1) is a well-described co-chaperone of the Hsp90 chaperone system, and our findings identify a potential regulatory role of STIP1 in actin dynamics. We show that STIP1 can be isolated in complex with actin and Hsp90 from HEK293T cells and directly interacts with actin in vitro via the C-terminal TPR2AB-DP2 domain of STIP1, potentially due to a region spanning two putative actin-binding motifs. We found that STIP1 could stimulate the in vitro ATPase activity of actin, suggesting a potential role in the modulation of F-actin formation. Interestingly, while STIP1 depletion in HEK293T cells had no major effect on total actin levels, it led to increased nuclear accumulation of actin, disorganization of F-actin structures, and an increase and decrease in cofilin and profilin levels, respectively. This study suggests that STIP1 regulates the cytoskeleton by interacting with actin, or via regulating the ratio of proteins known to affect actin dynamics.
- Full Text:
- Date Issued: 2020
Industrial relations in Namibia since independence: between neo-liberalism and neo-corporatism?
- Authors: Klerck, Gilton
- Date: 2008
- Language: English
- Type: Article
- Identifier: vital:6320 , http://hdl.handle.net/10962/d1011314
- Description: The paper seeks to examine the changes and continuities in industrial relations in post-independence Namibia. In particular, it aims to explore some of the key elements in the process through which the distribution of the costs and rewards of economic and industrial restructuring is institutionalised. The paper concentrates, through in-depth interviews with key role players, on how the attempts at sustaining a durable and redistributive trade-off between economic efficiency and social equality led to a contradictory fusion of neo-liberal and neo-corporatist forms of labour market regulation. The research reveals that changes in the regulation of the labour market since independence have created opportunities for advancement and participation by groups of more skilled and organised employees, while weaker and less skilled groups have generally experienced a decline in employment conditions and the absence of collective representation. These developments reflect and reproduce patterns of racial and gender discrimination, industrial structure, trade union membership and collective bargaining across the various sectors and occupations. The paper shows that a system of low-skill, low-wage and low-trust relations - with an emphasis on cost reduction and employment "flexibility" - is fast becoming embedded in industrial relations in Namibia. Given the prevailing economic policies, industrial strategies and labour market structures, Namibia's integration into the global economy will most likely involve the increasing dislocation and exclusion of vulnerable and "peripheral" workers from the formal economy. The paper highlights the ways in which the transformation of industrial relations in Namibia is shaped by the legacy of apartheid-colonialism and the pressures of globalisation. Specifically, the conjunction of increasingly deregulated product markets and increasingly regulated labour markets has driven a wedge between the pursuit of short-term objectives and the attainment of long-term transformational goals.
- Full Text:
- Date Issued: 2008
- Authors: Klerck, Gilton
- Date: 2008
- Language: English
- Type: Article
- Identifier: vital:6320 , http://hdl.handle.net/10962/d1011314
- Description: The paper seeks to examine the changes and continuities in industrial relations in post-independence Namibia. In particular, it aims to explore some of the key elements in the process through which the distribution of the costs and rewards of economic and industrial restructuring is institutionalised. The paper concentrates, through in-depth interviews with key role players, on how the attempts at sustaining a durable and redistributive trade-off between economic efficiency and social equality led to a contradictory fusion of neo-liberal and neo-corporatist forms of labour market regulation. The research reveals that changes in the regulation of the labour market since independence have created opportunities for advancement and participation by groups of more skilled and organised employees, while weaker and less skilled groups have generally experienced a decline in employment conditions and the absence of collective representation. These developments reflect and reproduce patterns of racial and gender discrimination, industrial structure, trade union membership and collective bargaining across the various sectors and occupations. The paper shows that a system of low-skill, low-wage and low-trust relations - with an emphasis on cost reduction and employment "flexibility" - is fast becoming embedded in industrial relations in Namibia. Given the prevailing economic policies, industrial strategies and labour market structures, Namibia's integration into the global economy will most likely involve the increasing dislocation and exclusion of vulnerable and "peripheral" workers from the formal economy. The paper highlights the ways in which the transformation of industrial relations in Namibia is shaped by the legacy of apartheid-colonialism and the pressures of globalisation. Specifically, the conjunction of increasingly deregulated product markets and increasingly regulated labour markets has driven a wedge between the pursuit of short-term objectives and the attainment of long-term transformational goals.
- Full Text:
- Date Issued: 2008
New and improved : Linda in Java
- Authors: Wells, George C
- Date: 2006
- Language: English
- Type: Article
- Identifier: vital:6613 , http://hdl.handle.net/10962/d1011511 , http://www.sciencedirect.com/science/article/pii/S0167642305000869
- Description: This paper discusses the current resurgence of interest in the Linda coordination language for parallel and distributed programming. Particularly in the Java field, there have been a number of developments over the past few years. These developments are summarised together with the advantages of using Linda for programming concurrent systems. Some problems with the basic Linda approach are also discussed and a novel solution to these is presented. The power and flexibility of the proposed extensions to the Linda programming model are illustrated by considering a number of example applications, including a detailed case study of visual language parsing.
- Full Text:
- Date Issued: 2006
- Authors: Wells, George C
- Date: 2006
- Language: English
- Type: Article
- Identifier: vital:6613 , http://hdl.handle.net/10962/d1011511 , http://www.sciencedirect.com/science/article/pii/S0167642305000869
- Description: This paper discusses the current resurgence of interest in the Linda coordination language for parallel and distributed programming. Particularly in the Java field, there have been a number of developments over the past few years. These developments are summarised together with the advantages of using Linda for programming concurrent systems. Some problems with the basic Linda approach are also discussed and a novel solution to these is presented. The power and flexibility of the proposed extensions to the Linda programming model are illustrated by considering a number of example applications, including a detailed case study of visual language parsing.
- Full Text:
- Date Issued: 2006
Rock magnetic stratigraphy of a mafic layered sill: a key to the Karoo volcanics plumbing system
- Maes, S M, Ferré, E E, Tikoff, B, Brown, P E, Marsh, Julian S
- Authors: Maes, S M , Ferré, E E , Tikoff, B , Brown, P E , Marsh, Julian S
- Date: 2008
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/144901 , vital:38389 , https://doi.org/10.1016/j.jvolgeores.2005.07.038
- Description: The Insizwa sill is an 1 km-thick subhorizontal layered mafic intrusion and part of the Karoo Large Igneous Province in South Africa. This well-exposed intrusion consists of several superimposed petrologically and geochemically distinct units. Magnetic methods were used to study the intrusion in order to constrain the physical processes active in these types of bodies during crystallization. Rock magnetism studies indicate that within different petrologic units bulk susceptibility is controlled by primary magnetite (with minor pyrrhotite) and/or paramagnetic minerals (olivine, pyroxene). New magnetic data based on 659 specimens obtained from 3 vertical borehole cores, each spaced 5 km apart, confirm the prominent vertical zonation in low field magnetic susceptibility (Klf), degree of anisotropy (Pj) and orientation of the anisotropy of magnetic susceptibility (AMS) axes.
- Full Text:
- Date Issued: 2008
- Authors: Maes, S M , Ferré, E E , Tikoff, B , Brown, P E , Marsh, Julian S
- Date: 2008
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/144901 , vital:38389 , https://doi.org/10.1016/j.jvolgeores.2005.07.038
- Description: The Insizwa sill is an 1 km-thick subhorizontal layered mafic intrusion and part of the Karoo Large Igneous Province in South Africa. This well-exposed intrusion consists of several superimposed petrologically and geochemically distinct units. Magnetic methods were used to study the intrusion in order to constrain the physical processes active in these types of bodies during crystallization. Rock magnetism studies indicate that within different petrologic units bulk susceptibility is controlled by primary magnetite (with minor pyrrhotite) and/or paramagnetic minerals (olivine, pyroxene). New magnetic data based on 659 specimens obtained from 3 vertical borehole cores, each spaced 5 km apart, confirm the prominent vertical zonation in low field magnetic susceptibility (Klf), degree of anisotropy (Pj) and orientation of the anisotropy of magnetic susceptibility (AMS) axes.
- Full Text:
- Date Issued: 2008
Familiar claims : representations of same-gendered families in South African mainstream news media
- Authors: Morison, Tracy , Reddy, Vasu
- Date: 2013
- Language: English
- Type: Book chapter
- Identifier: vital:6211 , http://hdl.handle.net/10962/d1003062
- Description: From the Introduction: There has been significant reform of South African legislation pertaining to same-gendered families. The Constitution supports the rights of gay men and lesbians to establish life partnerships or, more recently, to enter into civil unions, to adopt children, keep custody of their own children in divorce proceedings, and to undertake co-parenting of their created families. Despite—or maybe because of—these developments, public debate on these issues is as lively and vociferous as it has ever been. At the time of writing this chapter, for instance, a veteran journalist published a column in a national newspaper in which he denounced same-gendered family “arrangements” as “neither the norm nor ultimately desirable” (Mulholland, 2013). Children in same-gendered families must be informed of this, he claimed. His argument was unsupported, save for unsubstantiated claims regarding the unnaturalness of same-gendered families, which defy “the natural order of things”, and the vehement refusal that “same-sex matrimony is the same as that of heterosexuals” (Mulholland, 2013). Mulholland’s column, which met with outrage by various activists and academics, demonstrates some of the ideas that circulate in public discussion of same-gendered families: concerns regarding the differences between homosexual and heterosexual families and the effects that these ‘differences’ might have on children living in ‘alternative’ families. In this chapter, we examine the public discussion, focusing on South African print media as a key site where debate has occurred. Recognising that the discussion of LGBTI issues in South Africa has increased in visibility over time, focusing on stories about coming out, rights, transgressions, stigma, discrimination and violence, this chapter concentrates on the public discussion in local print media that centre on ‘alternative’ family arrangements that are in contrast to a traditional heterosexual nuclear family. Drawing on a selection of print media reportage, we examine the social and public discourses that underpin and resist normative meanings associated with ‘the family’ as a social unit and, specifically, how same-gendered families (often rendered invisible and pathologised) are constructed within this material. , C. Lubbe & J. Marnell (Eds.) 2013. Home affairs: rethinking lesbian, gay, bisexual & transgender families in contemporary South Africa. A copy of the book can be obtained from: http://www.jacana.co.za
- Full Text:
- Date Issued: 2013
- Authors: Morison, Tracy , Reddy, Vasu
- Date: 2013
- Language: English
- Type: Book chapter
- Identifier: vital:6211 , http://hdl.handle.net/10962/d1003062
- Description: From the Introduction: There has been significant reform of South African legislation pertaining to same-gendered families. The Constitution supports the rights of gay men and lesbians to establish life partnerships or, more recently, to enter into civil unions, to adopt children, keep custody of their own children in divorce proceedings, and to undertake co-parenting of their created families. Despite—or maybe because of—these developments, public debate on these issues is as lively and vociferous as it has ever been. At the time of writing this chapter, for instance, a veteran journalist published a column in a national newspaper in which he denounced same-gendered family “arrangements” as “neither the norm nor ultimately desirable” (Mulholland, 2013). Children in same-gendered families must be informed of this, he claimed. His argument was unsupported, save for unsubstantiated claims regarding the unnaturalness of same-gendered families, which defy “the natural order of things”, and the vehement refusal that “same-sex matrimony is the same as that of heterosexuals” (Mulholland, 2013). Mulholland’s column, which met with outrage by various activists and academics, demonstrates some of the ideas that circulate in public discussion of same-gendered families: concerns regarding the differences between homosexual and heterosexual families and the effects that these ‘differences’ might have on children living in ‘alternative’ families. In this chapter, we examine the public discussion, focusing on South African print media as a key site where debate has occurred. Recognising that the discussion of LGBTI issues in South Africa has increased in visibility over time, focusing on stories about coming out, rights, transgressions, stigma, discrimination and violence, this chapter concentrates on the public discussion in local print media that centre on ‘alternative’ family arrangements that are in contrast to a traditional heterosexual nuclear family. Drawing on a selection of print media reportage, we examine the social and public discourses that underpin and resist normative meanings associated with ‘the family’ as a social unit and, specifically, how same-gendered families (often rendered invisible and pathologised) are constructed within this material. , C. Lubbe & J. Marnell (Eds.) 2013. Home affairs: rethinking lesbian, gay, bisexual & transgender families in contemporary South Africa. A copy of the book can be obtained from: http://www.jacana.co.za
- Full Text:
- Date Issued: 2013
Creating learning and action space in South Africa’s post-apartheid land redistribution program:
- Authors: Kepe, Thembela , Hall, Ruth
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163842 , vital:41075 , https://0-doi.org.wam.seals.ac.za/10.1177/1476750317705966
- Description: This paper uses the case of South Africa’s latest land redistribution strategy known as the Proactive Land Acquisition Strategy, to explore whether, and how, research can have direct and positive impacts on beneficiaries of land reform. The study is situated within the practice of action research: to explore how it can generate knowledge that can be shared back and forth between stakeholders, as well as how it may ignite changes that the participants desire.
- Full Text:
- Date Issued: 2020
- Authors: Kepe, Thembela , Hall, Ruth
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163842 , vital:41075 , https://0-doi.org.wam.seals.ac.za/10.1177/1476750317705966
- Description: This paper uses the case of South Africa’s latest land redistribution strategy known as the Proactive Land Acquisition Strategy, to explore whether, and how, research can have direct and positive impacts on beneficiaries of land reform. The study is situated within the practice of action research: to explore how it can generate knowledge that can be shared back and forth between stakeholders, as well as how it may ignite changes that the participants desire.
- Full Text:
- Date Issued: 2020
Soft believers and hard unbelievers in the Xhosa cattle-killing
- Authors: Peires, Jeffrey B
- Date: 1986
- Language: English
- Type: Article
- Identifier: vital:6153 , http://hdl.handle.net/10962/d1007064 , http://dx.doi.org/10.1017/S0021853700023264
- Description: A substantial minority, perhaps 15 per cent of all Xhosa, refused to obey the prophetess Nongqawuse's orders to kill their cattle and destroy their corn. This divided Xhosaland into two parties, the amathamba (‘soft’ ones, or believers) and the amagogotya (‘hard’ ones, or unbelievers). The affiliation of individuals was partly determined by a number of factors – lungsickness in cattle, political attitude towards the Cape Colony, religious beliefs, kinship, age and gender – but a systematic analysis of each of these factors in turn suggests that none of them was sufficiently important to constitute the basis of either party. The key to understanding the division lies in an analysis of the indigenous Xhosa terms ‘soft’ and ‘hard’. ‘Softness’ in Xhosa denotes the submissiveness of the individual to the common will of the community, whereas ‘hardness’ denotes the determination of the individual to pursue his own ends, even at communal expense. Translated into social terms, the ‘soft’ believers were those who remained committed to the mutual aid ethic of the declining precolonial society, whereas the ‘hard’ unbelievers were those who sought to seize advantage of the new opportunities offered by the colonial presence to increase their wealth and social prominence. The conflict between the social and personal imperatives was well expressed by Chief Smith Mhala, the unbelieving son of a believing father, when he said, ‘They say I am killing my father – so I would kill him before I would kill my cattle.’ Certainly, the division between amathamba and amagogotya ran much deeper than the division between belief and unbelief, and the Xhosa, in conferring these names, seem to have recognized the fact.
- Full Text:
- Date Issued: 1986
- Authors: Peires, Jeffrey B
- Date: 1986
- Language: English
- Type: Article
- Identifier: vital:6153 , http://hdl.handle.net/10962/d1007064 , http://dx.doi.org/10.1017/S0021853700023264
- Description: A substantial minority, perhaps 15 per cent of all Xhosa, refused to obey the prophetess Nongqawuse's orders to kill their cattle and destroy their corn. This divided Xhosaland into two parties, the amathamba (‘soft’ ones, or believers) and the amagogotya (‘hard’ ones, or unbelievers). The affiliation of individuals was partly determined by a number of factors – lungsickness in cattle, political attitude towards the Cape Colony, religious beliefs, kinship, age and gender – but a systematic analysis of each of these factors in turn suggests that none of them was sufficiently important to constitute the basis of either party. The key to understanding the division lies in an analysis of the indigenous Xhosa terms ‘soft’ and ‘hard’. ‘Softness’ in Xhosa denotes the submissiveness of the individual to the common will of the community, whereas ‘hardness’ denotes the determination of the individual to pursue his own ends, even at communal expense. Translated into social terms, the ‘soft’ believers were those who remained committed to the mutual aid ethic of the declining precolonial society, whereas the ‘hard’ unbelievers were those who sought to seize advantage of the new opportunities offered by the colonial presence to increase their wealth and social prominence. The conflict between the social and personal imperatives was well expressed by Chief Smith Mhala, the unbelieving son of a believing father, when he said, ‘They say I am killing my father – so I would kill him before I would kill my cattle.’ Certainly, the division between amathamba and amagogotya ran much deeper than the division between belief and unbelief, and the Xhosa, in conferring these names, seem to have recognized the fact.
- Full Text:
- Date Issued: 1986
Representations of gender and agency in the Harry Potter series:
- Authors: Hunt, Sally
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/139269 , vital:37721 , ISBN 978-1-137-43173-8 , https://doi.org/10.1057/9781137431738_13
- Description: Gender is an all-pervasive and extremely influential construct in the lives of individuals (Taylor, 2003). In children’s literature, we find a reflection of the attitudes towards gender prevalent in a given society at a particular time (Peterson and Lach, 1990). Therefore the study of how gender is represented in children’s literature can make a useful contribution to our understanding of how choices in language use support particular discourses, ‘broad constitutive systems of meaning’ (Sunderland, 2004: 6) or ‘ways of seeing the world’ (op cit: 28). These representations in turn perpetuate prevailing gendered power relations in that society, as research into children’s literature has shown (Thompson and Sealey, 2007). Corpus Linguistics offers a degree of objectivity and efficiency not possible in manual ideological analysis, as well as a set of tools particularly useful for the lexical analysis of considerable quantities of text. In this chapter, I report on my analysis of gendered discourses in the Harry Potter series by J. K. Rowling, focussing on patterns around grammatical agency in the books.
- Full Text:
- Date Issued: 2015
- Authors: Hunt, Sally
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/139269 , vital:37721 , ISBN 978-1-137-43173-8 , https://doi.org/10.1057/9781137431738_13
- Description: Gender is an all-pervasive and extremely influential construct in the lives of individuals (Taylor, 2003). In children’s literature, we find a reflection of the attitudes towards gender prevalent in a given society at a particular time (Peterson and Lach, 1990). Therefore the study of how gender is represented in children’s literature can make a useful contribution to our understanding of how choices in language use support particular discourses, ‘broad constitutive systems of meaning’ (Sunderland, 2004: 6) or ‘ways of seeing the world’ (op cit: 28). These representations in turn perpetuate prevailing gendered power relations in that society, as research into children’s literature has shown (Thompson and Sealey, 2007). Corpus Linguistics offers a degree of objectivity and efficiency not possible in manual ideological analysis, as well as a set of tools particularly useful for the lexical analysis of considerable quantities of text. In this chapter, I report on my analysis of gendered discourses in the Harry Potter series by J. K. Rowling, focussing on patterns around grammatical agency in the books.
- Full Text:
- Date Issued: 2015
The reception and codification of systems of law in Southern Africa
- Authors: Kerr, A J
- Date: 1958
- Language: English
- Type: Article
- Identifier: vital:6339 , http://hdl.handle.net/10962/d1012404
- Description: The problems of reception and codification discussed by Dr. A. N. Allott in his article on “The Authority of English Decisions in Colonial Courts” in [1957] 1 J.A.L. 23 et seq. have also been encountered in Southern Africa and something of interest and value may be found in an account of experience of the problems in this area.
- Full Text:
- Date Issued: 1958
- Authors: Kerr, A J
- Date: 1958
- Language: English
- Type: Article
- Identifier: vital:6339 , http://hdl.handle.net/10962/d1012404
- Description: The problems of reception and codification discussed by Dr. A. N. Allott in his article on “The Authority of English Decisions in Colonial Courts” in [1957] 1 J.A.L. 23 et seq. have also been encountered in Southern Africa and something of interest and value may be found in an account of experience of the problems in this area.
- Full Text:
- Date Issued: 1958