Using visuals to communicate medicine information to patients with low literacy:
- Authors: Dowse, Roslind
- Date: 2004
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156958 , vital:40073 , https://journals.sagepub.com/doi/pdf/10.1177/104515950401500106
- Description: The patient was adamant that she had taken her medicine as instructed, pointing to the visual (Visual 1) illustrating the instructions to endorse this. Via an interpreter, she communicated that she took her tablet three times during the day and once at night (which was correct), but only on those days when the sun was shining (not on cloudy days) and the moon was visible (depending on both cloud cover and phases of the moon).
- Full Text:
- Date Issued: 2004
- Authors: Dowse, Roslind
- Date: 2004
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156958 , vital:40073 , https://journals.sagepub.com/doi/pdf/10.1177/104515950401500106
- Description: The patient was adamant that she had taken her medicine as instructed, pointing to the visual (Visual 1) illustrating the instructions to endorse this. Via an interpreter, she communicated that she took her tablet three times during the day and once at night (which was correct), but only on those days when the sun was shining (not on cloudy days) and the moon was visible (depending on both cloud cover and phases of the moon).
- Full Text:
- Date Issued: 2004
Isolation of genes encoding heat shock protein 70 (hsp70s) from the coelacanth, Latimeria chalumnae
- Modisakeng, Keoagile W, Dorrington, Rosemary A, Blatch, Gregory L
- Authors: Modisakeng, Keoagile W , Dorrington, Rosemary A , Blatch, Gregory L
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6459 , http://hdl.handle.net/10962/d1005788
- Description: Under stress conditions, proteins unfold or misfold, leading to the formation of aggregates. Molecular chaperones can be defined as proteins that facilitate the correct folding of other proteins, so that they attain a stable tertiary structure. In addition, they promote the refolding and degradation of denatured proteins after cellular stress. Heat shock proteins form one of the main classes of molecular chaperones. We are interested in determining if the genome of the coelacanth (Latimeria chalumnae) encodes a heat shock protein-based cytoprotection mechanism. We have isolated 50 kb and larger coelacanth genomic DNA from frozen skin tissue of L. chalumnae. From the alignments of several fish Hsp70 proteins, conserved regions at the N- and C-termini were identified. Codon usage tables were constructed from published coelacanth genes and degenerate primers were designed to isolate the full-length hsp70 gene and regions encoding the ATPase and the peptide binding domains. Since it is known that the tilapia and Fugu inducible hsp70 genes are intronless, we proceeded on the assumption that a coelacanth inducible hsp70 would also be intronless. A large fragment (1840 bp) encoding most of a coelacanth Hsp70 protein, and two partial fragments encoding a coelacanth Hsp70ATPase domain (1048 bp) and peptide binding domain (873 bp), were isolated by polymerase chain reaction amplification. Protein sequences translated from all the nucleotide sequences were closely identical to typical Hsp70s. This is the first study to provide evidence for a cytoprotection mechanism in the coelacanth involving an inducible Hsp70.
- Full Text:
- Date Issued: 2004
- Authors: Modisakeng, Keoagile W , Dorrington, Rosemary A , Blatch, Gregory L
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6459 , http://hdl.handle.net/10962/d1005788
- Description: Under stress conditions, proteins unfold or misfold, leading to the formation of aggregates. Molecular chaperones can be defined as proteins that facilitate the correct folding of other proteins, so that they attain a stable tertiary structure. In addition, they promote the refolding and degradation of denatured proteins after cellular stress. Heat shock proteins form one of the main classes of molecular chaperones. We are interested in determining if the genome of the coelacanth (Latimeria chalumnae) encodes a heat shock protein-based cytoprotection mechanism. We have isolated 50 kb and larger coelacanth genomic DNA from frozen skin tissue of L. chalumnae. From the alignments of several fish Hsp70 proteins, conserved regions at the N- and C-termini were identified. Codon usage tables were constructed from published coelacanth genes and degenerate primers were designed to isolate the full-length hsp70 gene and regions encoding the ATPase and the peptide binding domains. Since it is known that the tilapia and Fugu inducible hsp70 genes are intronless, we proceeded on the assumption that a coelacanth inducible hsp70 would also be intronless. A large fragment (1840 bp) encoding most of a coelacanth Hsp70 protein, and two partial fragments encoding a coelacanth Hsp70ATPase domain (1048 bp) and peptide binding domain (873 bp), were isolated by polymerase chain reaction amplification. Protein sequences translated from all the nucleotide sequences were closely identical to typical Hsp70s. This is the first study to provide evidence for a cytoprotection mechanism in the coelacanth involving an inducible Hsp70.
- Full Text:
- Date Issued: 2004
Women and Water: How is Gender Policy Working on the Ground The Water Wheel
- Authors: Berold, Robert
- Date: 2004
- Subjects: To be catalogued
- Language: English
- Type: text , report
- Identifier: http://hdl.handle.net/10962/437684 , vital:73402 , ISBN report , https://wrcwebsite.azurewebsites.net/wp-content/uploads/mdocs/WW_04_mar-apr_WiW.pdf
- Description: The gender policy of the Department of Water Affairs and Forestry (DWAF), formu-lated in 1997, was designed to promote gender equality both within DWAF itself and in its activities at community level. The policy required a quota of at least 30% (since increased to 50%) of women in all decision-making committees as well as adequate participation and technical training. How does the policy work out in the rural areas, far away from DWAF head office in Pretoria? The Water Research Commission (WRC) conducted a research study in the Peddie area to find out. Fort Hare lecturer Priscilla Monyai looked at four villages close to the town of Peddie in the densely populated former Ciskei, between Grahamstown and King Williams Town. About 4 000 people live in the villages of Cisira, Ncala, Nqwenerana and Mgwangqa. All get their water from the Peddie water supply scheme which began supplying clean drinking water in 1999.
- Full Text:
- Date Issued: 2004
- Authors: Berold, Robert
- Date: 2004
- Subjects: To be catalogued
- Language: English
- Type: text , report
- Identifier: http://hdl.handle.net/10962/437684 , vital:73402 , ISBN report , https://wrcwebsite.azurewebsites.net/wp-content/uploads/mdocs/WW_04_mar-apr_WiW.pdf
- Description: The gender policy of the Department of Water Affairs and Forestry (DWAF), formu-lated in 1997, was designed to promote gender equality both within DWAF itself and in its activities at community level. The policy required a quota of at least 30% (since increased to 50%) of women in all decision-making committees as well as adequate participation and technical training. How does the policy work out in the rural areas, far away from DWAF head office in Pretoria? The Water Research Commission (WRC) conducted a research study in the Peddie area to find out. Fort Hare lecturer Priscilla Monyai looked at four villages close to the town of Peddie in the densely populated former Ciskei, between Grahamstown and King Williams Town. About 4 000 people live in the villages of Cisira, Ncala, Nqwenerana and Mgwangqa. All get their water from the Peddie water supply scheme which began supplying clean drinking water in 1999.
- Full Text:
- Date Issued: 2004
A yellowwood by any other name: molecular systematics and the taxonomy of Podocarpus and the Podocarpaceae in southern Africa
- Barker, Nigel P, Muller, E M, Mill, R R
- Authors: Barker, Nigel P , Muller, E M , Mill, R R
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6495 , http://hdl.handle.net/10962/d1004488
- Description: We briefly review the taxonomic history of the Podocarpaceae, with an emphasis on the recognition of numerous segregate genera out of Podocarpus sensu lato. Despite some controversy over the recognition of these genera, molecular data (DNA sequences) provide evidence that supports this taxonomy. The implications for African Podocarpaceae are discussed. In particular, molecular data support the recognition of Afrocarpus as distinct from Podocarpus. Additional taxonomic problems concerning the possible segregation of Podocarpus milanjianus from P. latifolius are addressed using DNA sequence data from the nuclear internal transcribed spacer 2 (ITS2) region. Results of this are inconclusive, and suggest that alternative DNA-based evidence, such as from AFLPs or microsatellites, may be more informative in resolving such species complexes in African Podocarpus.
- Full Text:
- Date Issued: 2004
- Authors: Barker, Nigel P , Muller, E M , Mill, R R
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6495 , http://hdl.handle.net/10962/d1004488
- Description: We briefly review the taxonomic history of the Podocarpaceae, with an emphasis on the recognition of numerous segregate genera out of Podocarpus sensu lato. Despite some controversy over the recognition of these genera, molecular data (DNA sequences) provide evidence that supports this taxonomy. The implications for African Podocarpaceae are discussed. In particular, molecular data support the recognition of Afrocarpus as distinct from Podocarpus. Additional taxonomic problems concerning the possible segregation of Podocarpus milanjianus from P. latifolius are addressed using DNA sequence data from the nuclear internal transcribed spacer 2 (ITS2) region. Results of this are inconclusive, and suggest that alternative DNA-based evidence, such as from AFLPs or microsatellites, may be more informative in resolving such species complexes in African Podocarpus.
- Full Text:
- Date Issued: 2004
Drimia chalumnensis (Hyacinthaceae - Urgineoideae), a new species from Eastern Cape, South Africa
- Dold, Anthony P, Brink, Estelle
- Authors: Dold, Anthony P , Brink, Estelle
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6516 , http://hdl.handle.net/10962/d1005944
- Description: Drimia chalumnensis, a new inconspicuous dwarf species from the Albany Centre of Floristic Endemism in Eastern Cape, South Africa, is restricted to the coastal plains of the Chalumna river in small scattered aggregated colonies on exposed sandstone sheets in pockets of loose sandy soil. It is distinguished by its capitate inflorescence, separate, petiolate bulb scales, and prostrate, coriaceous, linear-lanceolate leaves with cartilaginous margins.
- Full Text:
- Date Issued: 2004
- Authors: Dold, Anthony P , Brink, Estelle
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6516 , http://hdl.handle.net/10962/d1005944
- Description: Drimia chalumnensis, a new inconspicuous dwarf species from the Albany Centre of Floristic Endemism in Eastern Cape, South Africa, is restricted to the coastal plains of the Chalumna river in small scattered aggregated colonies on exposed sandstone sheets in pockets of loose sandy soil. It is distinguished by its capitate inflorescence, separate, petiolate bulb scales, and prostrate, coriaceous, linear-lanceolate leaves with cartilaginous margins.
- Full Text:
- Date Issued: 2004
A new broom: feature
- Cocks, Michelle L, Dold, Anthony P, Sizane, Nomtunzi
- Authors: Cocks, Michelle L , Dold, Anthony P , Sizane, Nomtunzi
- Date: 2004
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/141404 , vital:37969 , https://hdl.handle.net/10520/EJC112779
- Description: Traditional grass brooms keep certain cultural practices alive in urban areas and provide rural people with a means to earn an income.
- Full Text:
- Date Issued: 2004
- Authors: Cocks, Michelle L , Dold, Anthony P , Sizane, Nomtunzi
- Date: 2004
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/141404 , vital:37969 , https://hdl.handle.net/10520/EJC112779
- Description: Traditional grass brooms keep certain cultural practices alive in urban areas and provide rural people with a means to earn an income.
- Full Text:
- Date Issued: 2004
An interdisciplinary cruise dedicated to understanding ocean eddies upstream of the Prince Edward Islands
- Ansorge, Isabelle J, Froneman, P William, Lutjeharms, Johan R E, Bernard, Kim S, Lange, Louise, Lukáč, D, Backburg, B, Blake, Justin, Bland, S, Burls, N, Davies-Coleman, Michael T, Gerber, R, Gildenhuys, S, Hayes-Foley, P, Ludford, A, Manzoni, T, Robertson, E, Southey, D, Swart, S, Van Rensburg, D, Wynne, S
- Authors: Ansorge, Isabelle J , Froneman, P William , Lutjeharms, Johan R E , Bernard, Kim S , Lange, Louise , Lukáč, D , Backburg, B , Blake, Justin , Bland, S , Burls, N , Davies-Coleman, Michael T , Gerber, R , Gildenhuys, S , Hayes-Foley, P , Ludford, A , Manzoni, T , Robertson, E , Southey, D , Swart, S , Van Rensburg, D , Wynne, S
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6830 , http://hdl.handle.net/10962/d1007566
- Description: A detailed hydrographic and biological survey was carried out in the region of the South-West Indian Ridge during April 2004. Altimetry and hydrographic data have identified this region as an area of high flow variability. Hydrographic data revealed that here the Subantarctic Polar Front (SAF) and Antarctic Polar Front (APF) converge to form a highly intense frontal system. Water masses identified during the survey showed a distinct separation in properties between the northwestern and southeastern corners. In the north-west, water masses were distinctly Subantarctic (>8.5°C, salinity >34.2), suggesting that the SAF lay extremely far to the south. In the southeast corner water masses were typical of the Antarctic zone, showing a distinct subsurface temperature minimum of <2.5°C. Total integrated chl-a concentration during the survey ranged from 4.15 to 22.81 mg chl-a m[superscript (-2)], with the highest concentrations recorded at stations occupied in the frontal region. These data suggest that the region of the South-West Indian Ridge represents not only an area of elevated biological activity but also acts as a strong biogeographic barrier to the spatial distribution of zooplankton.
- Full Text:
- Date Issued: 2004
- Authors: Ansorge, Isabelle J , Froneman, P William , Lutjeharms, Johan R E , Bernard, Kim S , Lange, Louise , Lukáč, D , Backburg, B , Blake, Justin , Bland, S , Burls, N , Davies-Coleman, Michael T , Gerber, R , Gildenhuys, S , Hayes-Foley, P , Ludford, A , Manzoni, T , Robertson, E , Southey, D , Swart, S , Van Rensburg, D , Wynne, S
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6830 , http://hdl.handle.net/10962/d1007566
- Description: A detailed hydrographic and biological survey was carried out in the region of the South-West Indian Ridge during April 2004. Altimetry and hydrographic data have identified this region as an area of high flow variability. Hydrographic data revealed that here the Subantarctic Polar Front (SAF) and Antarctic Polar Front (APF) converge to form a highly intense frontal system. Water masses identified during the survey showed a distinct separation in properties between the northwestern and southeastern corners. In the north-west, water masses were distinctly Subantarctic (>8.5°C, salinity >34.2), suggesting that the SAF lay extremely far to the south. In the southeast corner water masses were typical of the Antarctic zone, showing a distinct subsurface temperature minimum of <2.5°C. Total integrated chl-a concentration during the survey ranged from 4.15 to 22.81 mg chl-a m[superscript (-2)], with the highest concentrations recorded at stations occupied in the frontal region. These data suggest that the region of the South-West Indian Ridge represents not only an area of elevated biological activity but also acts as a strong biogeographic barrier to the spatial distribution of zooplankton.
- Full Text:
- Date Issued: 2004
Concerning secondary thermoluminescence peaks in α-Al_2_O_3_:C
- Authors: Chithambo, Makaiko L
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6793 , http://hdl.handle.net/10962/d1003823
- Description: Thermoluminescence characteristics of two subsidiary glow peaks, one below 100°C and the other above 300°C, have been studied for measurements between 30°C and 500°C in α-Al_2_O_3_:C. The thermoluminescence intensity of the lower temperature peak decreased with storage with a half-life of about 150 s. In contrast, the intensity of the higher temperature peak increased with storage towards some maximum. The peak-temperature of each of the secondary glow peaks was essentially constant with dose, whereas that of the main peak decreased with irradiation. The dose response for the three peaks was similar except for sublinear growth in the higher temperature peak at low dose values. These effects are discussed in terms of changes in the concentration of F+ luminescence precursors brought about by competitive electron retrapping at deep electron-traps or hole-traps. This work refines the physics and application of α-Al_2_O_3_:C luminescence in radiation dosimetry.
- Full Text:
- Date Issued: 2004
- Authors: Chithambo, Makaiko L
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6793 , http://hdl.handle.net/10962/d1003823
- Description: Thermoluminescence characteristics of two subsidiary glow peaks, one below 100°C and the other above 300°C, have been studied for measurements between 30°C and 500°C in α-Al_2_O_3_:C. The thermoluminescence intensity of the lower temperature peak decreased with storage with a half-life of about 150 s. In contrast, the intensity of the higher temperature peak increased with storage towards some maximum. The peak-temperature of each of the secondary glow peaks was essentially constant with dose, whereas that of the main peak decreased with irradiation. The dose response for the three peaks was similar except for sublinear growth in the higher temperature peak at low dose values. These effects are discussed in terms of changes in the concentration of F+ luminescence precursors brought about by competitive electron retrapping at deep electron-traps or hole-traps. This work refines the physics and application of α-Al_2_O_3_:C luminescence in radiation dosimetry.
- Full Text:
- Date Issued: 2004
Quantification of the photosynthetic performance of phosphorus-deficient Sorghum by means of chlorophyll-a fluorescence kinetics
- Ripley, Bradford S, Redfern, S P, Dames, Joanna F
- Authors: Ripley, Bradford S , Redfern, S P , Dames, Joanna F
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6456 , http://hdl.handle.net/10962/d1004464
- Description: Chlorophyll fluorescence induction curves have been used as a sensitive tool for screening the photosynthetic performance of plants. Experimental treatments involving nitrate supply and chilling stress have been shown to affect fluorescence induction curves and other measures of photosynthesis. We have investigated the photosynthetic performance of Sorghum bicolor supplied with Long Ashton growth solution containing standard (20 μmol mol^(–1)) or low (5 μmol mol^(–1)) phosphorus. The JIP-test based on the chlorophyll fluorescence induction curve was used as a non-destructive method to measure the relative proportions of energy dissipated by different processes (termed energy fluxes) in the light reactions. The various energy fluxes or derived parameters were compared to find the measures that were most sensitive to the experimental conditions. Plant response to treatments was first evident in selected chlorophyll fluorescence parameters, particularly performance index (PI_ABS_); plants with increased PI_ABS_ manifested higher electron transport activity and dissipated less energy as heat, possibly as a result of their better phosphorus status, leading to more functional reaction centres. Observed changes in fluorescence were correlated to changes in gas exchange and biomass. Standard phosphorus treatments significantly increased biomass, leaf area, photosynthetic and respiratory rates, carboxylation efficiencies and levels of ribulose biphosphate regeneration rates, relative to plants with low supplies of nutrients.
- Full Text:
- Date Issued: 2004
- Authors: Ripley, Bradford S , Redfern, S P , Dames, Joanna F
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6456 , http://hdl.handle.net/10962/d1004464
- Description: Chlorophyll fluorescence induction curves have been used as a sensitive tool for screening the photosynthetic performance of plants. Experimental treatments involving nitrate supply and chilling stress have been shown to affect fluorescence induction curves and other measures of photosynthesis. We have investigated the photosynthetic performance of Sorghum bicolor supplied with Long Ashton growth solution containing standard (20 μmol mol^(–1)) or low (5 μmol mol^(–1)) phosphorus. The JIP-test based on the chlorophyll fluorescence induction curve was used as a non-destructive method to measure the relative proportions of energy dissipated by different processes (termed energy fluxes) in the light reactions. The various energy fluxes or derived parameters were compared to find the measures that were most sensitive to the experimental conditions. Plant response to treatments was first evident in selected chlorophyll fluorescence parameters, particularly performance index (PI_ABS_); plants with increased PI_ABS_ manifested higher electron transport activity and dissipated less energy as heat, possibly as a result of their better phosphorus status, leading to more functional reaction centres. Observed changes in fluorescence were correlated to changes in gas exchange and biomass. Standard phosphorus treatments significantly increased biomass, leaf area, photosynthetic and respiratory rates, carboxylation efficiencies and levels of ribulose biphosphate regeneration rates, relative to plants with low supplies of nutrients.
- Full Text:
- Date Issued: 2004
The Baylis-Hillman entrée to heterocyclic systems — the Rhodes contribution
- Authors: Kaye, Perry T
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6575 , http://hdl.handle.net/10962/d1004138
- Description: This review focuses on applications of the Baylis-Hillman reaction in the synthesis of various heterocyclic products, which include indolizines, chromenes, thiochromenes, coumarins and quinolines. Attention is also given to the mechanistic implications and the elaboration of various products to afford compounds with medicinal potential.
- Full Text:
- Date Issued: 2004
- Authors: Kaye, Perry T
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6575 , http://hdl.handle.net/10962/d1004138
- Description: This review focuses on applications of the Baylis-Hillman reaction in the synthesis of various heterocyclic products, which include indolizines, chromenes, thiochromenes, coumarins and quinolines. Attention is also given to the mechanistic implications and the elaboration of various products to afford compounds with medicinal potential.
- Full Text:
- Date Issued: 2004
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