IT Method: MCT 411
- Authors: Xazela, M W , Cetywayo, N
- Date: 2011-06
- Subjects: Education
- Language: English
- Type: Examination paper
- Identifier: vital:17318 , http://hdl.handle.net/10353/d1010165
- Description: Examination on IT Method: MCT 411, June 2011.
- Full Text: false
- Date Issued: 2011-06
- Authors: Xazela, M W , Cetywayo, N
- Date: 2011-06
- Subjects: Education
- Language: English
- Type: Examination paper
- Identifier: vital:17318 , http://hdl.handle.net/10353/d1010165
- Description: Examination on IT Method: MCT 411, June 2011.
- Full Text: false
- Date Issued: 2011-06
Learning Zulu: a secret history of language in South Africa
- Authors: Wylie, Dan
- Date: 2017
- Language: English
- Type: book review , text
- Identifier: http://hdl.handle.net/10962/61255 , vital:27997 , https://www.ajol.info/index.php/tvl/article/view/160848
- Description: Taking a leaf from the book under review, I’ll start by injecting an autobiographical element. Much of what Sanders examines here echoes my own experience, after Zimbabwe’s independence, of heading to a remote mission school to teach for two years. Part of my purpose was to learn better Shona, the majority language from which I had been systematically discouraged by my colonial education. It was, in a way, a gesture of reparation, or addressing a nagging “white guilt”, or at least of assuaging a sense of fruitless loss and exclusion. I was nowhere near as successful in attaining fluency as Sanders seems have been in learning Zulu; and now that I live in the Eastern Cape, my efforts to learn Xhosa have been similarly patchy and faltering. One thing is evident throughout Sanders’s dense discussions: long-term, assiduous application and pe¬riods of total immersion are vital—and as he points out, few whites in South Africa have carved out the time and energy to do so, while willy-nilly expecting the black majority to learn their language. (An endnote does aver that, according to census figures, a surprising 16,000-plus whites, and a similar number of Indians, in KwaZulu-Natal, list Zulu as their first language.)
- Full Text:
- Date Issued: 2017
- Authors: Wylie, Dan
- Date: 2017
- Language: English
- Type: book review , text
- Identifier: http://hdl.handle.net/10962/61255 , vital:27997 , https://www.ajol.info/index.php/tvl/article/view/160848
- Description: Taking a leaf from the book under review, I’ll start by injecting an autobiographical element. Much of what Sanders examines here echoes my own experience, after Zimbabwe’s independence, of heading to a remote mission school to teach for two years. Part of my purpose was to learn better Shona, the majority language from which I had been systematically discouraged by my colonial education. It was, in a way, a gesture of reparation, or addressing a nagging “white guilt”, or at least of assuaging a sense of fruitless loss and exclusion. I was nowhere near as successful in attaining fluency as Sanders seems have been in learning Zulu; and now that I live in the Eastern Cape, my efforts to learn Xhosa have been similarly patchy and faltering. One thing is evident throughout Sanders’s dense discussions: long-term, assiduous application and pe¬riods of total immersion are vital—and as he points out, few whites in South Africa have carved out the time and energy to do so, while willy-nilly expecting the black majority to learn their language. (An endnote does aver that, according to census figures, a surprising 16,000-plus whites, and a similar number of Indians, in KwaZulu-Natal, list Zulu as their first language.)
- Full Text:
- Date Issued: 2017
Guy Butler: 21 January 1918 - 26 April 2001
- Authors: Wright, Laurence
- Date: 2001
- Language: English
- Type: Article
- Identifier: vital:7053 , http://hdl.handle.net/10962/d1007413
- Description: [From Introduction]: For much of the last twenty-five years of his life, Butler’s thought and work were not perceived to be ‘current’ at all. His poetry was hardly read (what’s new there? – neither is anyone else’s); some of it lay in manuscript or obscure little publications until the Collected Poems appeared in 1999. The autobiographies attracted a loyal following amongst a small, educated reading public. His early dramas, though they met with initial success, were stifled by the poetic idiom to which they aspired, and by the racial claustrophobia against which they fought. (Demea, Butler’s South African reworking of the Medea, made it to the boards only in 1990 – the multi-racial cast, let alone the themes, kept it in hibernation until then.) The deluge of journalism and polemic suffered the usual fate of ephemera. Until resurrected by Stephen Watson in 1990, the essays and lectures remained buried in periodicals where they could not be assessed as a totality. His inspiring teaching was a gift to his students, hardly accessible to the wider society; and above all, much of his time was spent as homo commiticus, serving on the boards and sub-committees of numerous university institutions and other organizations, some of which he founded. In his autobiography, he observed wryly of his changed status following accession to the Chair of English at Rhodes in 1951: ‘Professors are not entirely themselves. Their interest as persons decreases because they are now public personages. Much of their time is spent on committees whose function is to pick the brains of individuals without giving them credit.’ Guy Butler gave generously of his brains in such circumstances.
- Full Text:
- Date Issued: 2001
- Authors: Wright, Laurence
- Date: 2001
- Language: English
- Type: Article
- Identifier: vital:7053 , http://hdl.handle.net/10962/d1007413
- Description: [From Introduction]: For much of the last twenty-five years of his life, Butler’s thought and work were not perceived to be ‘current’ at all. His poetry was hardly read (what’s new there? – neither is anyone else’s); some of it lay in manuscript or obscure little publications until the Collected Poems appeared in 1999. The autobiographies attracted a loyal following amongst a small, educated reading public. His early dramas, though they met with initial success, were stifled by the poetic idiom to which they aspired, and by the racial claustrophobia against which they fought. (Demea, Butler’s South African reworking of the Medea, made it to the boards only in 1990 – the multi-racial cast, let alone the themes, kept it in hibernation until then.) The deluge of journalism and polemic suffered the usual fate of ephemera. Until resurrected by Stephen Watson in 1990, the essays and lectures remained buried in periodicals where they could not be assessed as a totality. His inspiring teaching was a gift to his students, hardly accessible to the wider society; and above all, much of his time was spent as homo commiticus, serving on the boards and sub-committees of numerous university institutions and other organizations, some of which he founded. In his autobiography, he observed wryly of his changed status following accession to the Chair of English at Rhodes in 1951: ‘Professors are not entirely themselves. Their interest as persons decreases because they are now public personages. Much of their time is spent on committees whose function is to pick the brains of individuals without giving them credit.’ Guy Butler gave generously of his brains in such circumstances.
- Full Text:
- Date Issued: 2001
Guy Butler (obituary)
- Authors: Wright, Laurence
- Date: 1999
- Language: English
- Type: Article
- Identifier: vital:7052 , http://hdl.handle.net/10962/d1007411
- Description: An obituary focusing on Guy Butler's Shakespearean preoccupations. The 1999/2000 volume of Shakespeare in Southern Africa only appeared in 2001. The Butler obituary was included as a 'stop-press' item as the volume went to print, which accounts for the apparent anomaly between the date of publication and the date of Guy Butler's death.
- Full Text:
- Date Issued: 1999
- Authors: Wright, Laurence
- Date: 1999
- Language: English
- Type: Article
- Identifier: vital:7052 , http://hdl.handle.net/10962/d1007411
- Description: An obituary focusing on Guy Butler's Shakespearean preoccupations. The 1999/2000 volume of Shakespeare in Southern Africa only appeared in 2001. The Butler obituary was included as a 'stop-press' item as the volume went to print, which accounts for the apparent anomaly between the date of publication and the date of Guy Butler's death.
- Full Text:
- Date Issued: 1999
Introduction [to the book "Scatter the Shrilling Bones" by Sithembele Isaac Xhegwana]
- Authors: Wright, Laurence
- Date: 2003
- Language: English
- Type: text , article
- Identifier: vital:7056 , http://hdl.handle.net/10962/d1007417
- Description: preprint , Scatter the Shrilling Bones by Sithembele Xhegwana comprises an ordered sequence of poems that conveys a journey both literal and spiritual. Revisitation is the organizing principle of the collection – the return to rural sources and origins by a consciousness estranged and illumined by modernity (cf. ‘The Return’). Underlying the collection is the theme of the night journey, whose archetype in western culture is Odysseus’ descent to the underworld – a pattern identified as such in the concluding essay ‘Starting from my Place: Notes on an Aesthetic’. The underworld here is literally the return to the home territory – a journey from Cape Town to the rural Eastern Cape – but also a revisiting of the mental world of traditional Africa: ‘Here at home, here all guilt begins’ (‘Homecoming’). The return journey is haunted by nightmare memories of mental illness, the schizophrenic episodes accompanying (or occasioned by?) the poet’s initial encounters with modernity. This illness is represented as both pathological and cultural – a price paid for challenging and rejecting the old certainties while grappling with new assumptions: “He undermines the ancestors, That’s why he suffers. Let him.” (‘To Himself’)
- Full Text:
- Date Issued: 2003
- Authors: Wright, Laurence
- Date: 2003
- Language: English
- Type: text , article
- Identifier: vital:7056 , http://hdl.handle.net/10962/d1007417
- Description: preprint , Scatter the Shrilling Bones by Sithembele Xhegwana comprises an ordered sequence of poems that conveys a journey both literal and spiritual. Revisitation is the organizing principle of the collection – the return to rural sources and origins by a consciousness estranged and illumined by modernity (cf. ‘The Return’). Underlying the collection is the theme of the night journey, whose archetype in western culture is Odysseus’ descent to the underworld – a pattern identified as such in the concluding essay ‘Starting from my Place: Notes on an Aesthetic’. The underworld here is literally the return to the home territory – a journey from Cape Town to the rural Eastern Cape – but also a revisiting of the mental world of traditional Africa: ‘Here at home, here all guilt begins’ (‘Homecoming’). The return journey is haunted by nightmare memories of mental illness, the schizophrenic episodes accompanying (or occasioned by?) the poet’s initial encounters with modernity. This illness is represented as both pathological and cultural – a price paid for challenging and rejecting the old certainties while grappling with new assumptions: “He undermines the ancestors, That’s why he suffers. Let him.” (‘To Himself’)
- Full Text:
- Date Issued: 2003
Possible dosage regimens for topical steroids assessed by vasoconstrictor assays using multiple applications
- Woodford, R, Haigh, John M, Barry, B W
- Authors: Woodford, R , Haigh, John M , Barry, B W
- Date: 1983
- Language: English
- Type: Article
- Identifier: vital:6450 , http://hdl.handle.net/10962/d1006637
- Description: The bioavailabilities and activities of three amcinonide preparations and Betnovate cream were assessed using three multiple-dosage regimen vasoconstrictor assays in 10 volunteers. Applications were made once daily, twice daily and every alternate day with an initial three times daily loading dose applied on the first day only. Blanching responses first increased and then decreased due to tachyphylaxis. It is proposed that clinically the most advantageous dosage regimen is a once daily application with no loading dose.
- Full Text:
- Date Issued: 1983
- Authors: Woodford, R , Haigh, John M , Barry, B W
- Date: 1983
- Language: English
- Type: Article
- Identifier: vital:6450 , http://hdl.handle.net/10962/d1006637
- Description: The bioavailabilities and activities of three amcinonide preparations and Betnovate cream were assessed using three multiple-dosage regimen vasoconstrictor assays in 10 volunteers. Applications were made once daily, twice daily and every alternate day with an initial three times daily loading dose applied on the first day only. Blanching responses first increased and then decreased due to tachyphylaxis. It is proposed that clinically the most advantageous dosage regimen is a once daily application with no loading dose.
- Full Text:
- Date Issued: 1983
English Literature: ECL 110
- Wood, F, Blatchford, M, Formson, C, Mndebele, A T, Morkel, N
- Authors: Wood, F , Blatchford, M , Formson, C , Mndebele, A T , Morkel, N
- Date: 2011-06
- Language: English
- Type: Examination paper
- Identifier: vital:18308 , http://hdl.handle.net/10353/d1011418
- Description: English Literature: ECL 110, degree examination June 2011.
- Full Text: false
- Date Issued: 2011-06
- Authors: Wood, F , Blatchford, M , Formson, C , Mndebele, A T , Morkel, N
- Date: 2011-06
- Language: English
- Type: Examination paper
- Identifier: vital:18308 , http://hdl.handle.net/10353/d1011418
- Description: English Literature: ECL 110, degree examination June 2011.
- Full Text: false
- Date Issued: 2011-06
English: ECL 120
- Wood, F, Blatchford, M, Formson, C, Mndebele, A T, Morkel, N
- Authors: Wood, F , Blatchford, M , Formson, C , Mndebele, A T , Morkel, N
- Date: 2009-06
- Language: English
- Type: Examination paper
- Identifier: vital:18300 , http://hdl.handle.net/10353/d1011308
- Description: English: ECL 120, main examinations June 2009.
- Full Text: false
- Date Issued: 2009-06
- Authors: Wood, F , Blatchford, M , Formson, C , Mndebele, A T , Morkel, N
- Date: 2009-06
- Language: English
- Type: Examination paper
- Identifier: vital:18300 , http://hdl.handle.net/10353/d1011308
- Description: English: ECL 120, main examinations June 2009.
- Full Text: false
- Date Issued: 2009-06
English Module: ECL 120
- Wood, F, Blatchford, M, Formson, C, Mndebele, A T, Morkel, N
- Authors: Wood, F , Blatchford, M , Formson, C , Mndebele, A T , Morkel, N
- Date: 2010-11
- Language: English
- Type: Examination paper
- Identifier: vital:18327 , http://hdl.handle.net/10353/d1011453
- Description: English Module: ECL 120, main examination November 2010.
- Full Text: false
- Date Issued: 2010-11
- Authors: Wood, F , Blatchford, M , Formson, C , Mndebele, A T , Morkel, N
- Date: 2010-11
- Language: English
- Type: Examination paper
- Identifier: vital:18327 , http://hdl.handle.net/10353/d1011453
- Description: English Module: ECL 120, main examination November 2010.
- Full Text: false
- Date Issued: 2010-11
Graphicacy as a form of communication
- Authors: Wilmot, P Dianne
- Date: 1999
- Language: English
- Type: Article
- Identifier: vital:6091 , http://hdl.handle.net/10962/d1008613
- Description: Children of today inhabit a multi-dimensional world and in order to communicate effectively in it they need the ability to utilise four forms of communication namely, oracy, literacy, numeracy and graphicacy. Communicating in graphic form requires an ability to both encode and decode spatial information using symbols which requires the utilisation and application of spatial perceptual skills and concepts. The draft Curriculum Framework for General and Further Education and Training identifies graphic literacy as one of the critical outcomes of the new South African curriculum. Spatial information about the environment is most frequently communicated in the graphic mode. Yet if graphicacy is to be recognised as an essential mode of communication and, as such, a vital element in education, then we need to seek ways of developing and introducing an explicit and critical pedagogy in our schools to foster the development of graphic and critical graphic literacy. But first, the skills and concepts integral to graphicacy need to be identified and understood. This article provides a framework for thinking about graphicacy as a form of communication in the General Education and Training (GET) band, the compulsory component of South African education (Grades 1-9).
- Full Text: false
- Date Issued: 1999
- Authors: Wilmot, P Dianne
- Date: 1999
- Language: English
- Type: Article
- Identifier: vital:6091 , http://hdl.handle.net/10962/d1008613
- Description: Children of today inhabit a multi-dimensional world and in order to communicate effectively in it they need the ability to utilise four forms of communication namely, oracy, literacy, numeracy and graphicacy. Communicating in graphic form requires an ability to both encode and decode spatial information using symbols which requires the utilisation and application of spatial perceptual skills and concepts. The draft Curriculum Framework for General and Further Education and Training identifies graphic literacy as one of the critical outcomes of the new South African curriculum. Spatial information about the environment is most frequently communicated in the graphic mode. Yet if graphicacy is to be recognised as an essential mode of communication and, as such, a vital element in education, then we need to seek ways of developing and introducing an explicit and critical pedagogy in our schools to foster the development of graphic and critical graphic literacy. But first, the skills and concepts integral to graphicacy need to be identified and understood. This article provides a framework for thinking about graphicacy as a form of communication in the General Education and Training (GET) band, the compulsory component of South African education (Grades 1-9).
- Full Text: false
- Date Issued: 1999
Suspense, the serious and the superman:
- Authors: Western, Rat
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147726 , vital:38664 , https://doi.org/10.1080/00043389.2012.11877164
- Description: When considering what to do with one’s Friday night, probably very few people would consider a two-hour formal lecture a top priority. But this is a Friday night in Grahamstown, where novelty in leisure and entertainment choices, outside of festival time, is a rarity. It is therefore unsurprising that, on the evening of 11 November 2011, the Rhodes Box Theatre is packed by 7 pm with a variety of students, academics, members of the local alternative scene and the general public.
- Full Text:
- Date Issued: 2017
- Authors: Western, Rat
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147726 , vital:38664 , https://doi.org/10.1080/00043389.2012.11877164
- Description: When considering what to do with one’s Friday night, probably very few people would consider a two-hour formal lecture a top priority. But this is a Friday night in Grahamstown, where novelty in leisure and entertainment choices, outside of festival time, is a rarity. It is therefore unsurprising that, on the evening of 11 November 2011, the Rhodes Box Theatre is packed by 7 pm with a variety of students, academics, members of the local alternative scene and the general public.
- Full Text:
- Date Issued: 2017
Deviance and Social Inequality: SOC 122F
UN Decade on Ecosystem Restoration 2021–2030: what chance for success in restoring coastal ecosystems?
- Waltham, Nathan J, Elliott, Michael, Lee, Shing Yip, Lovelock, Catherine, Duarte, Carlos M, Buelow, Christina, Simenstad, Charles, Nagelkerken, Ivan, Claassens, Louw, Wen, Colin K-C, Barletta, Mario, Connolly, Rod M, Gillies, Chris, Mitsch, William J, Ogburn, Matthew B, Purandare, Jemma, Possingham, Hugh, Sheaves, Marcus
- Authors: Waltham, Nathan J , Elliott, Michael , Lee, Shing Yip , Lovelock, Catherine , Duarte, Carlos M , Buelow, Christina , Simenstad, Charles , Nagelkerken, Ivan , Claassens, Louw , Wen, Colin K-C , Barletta, Mario , Connolly, Rod M , Gillies, Chris , Mitsch, William J , Ogburn, Matthew B , Purandare, Jemma , Possingham, Hugh , Sheaves, Marcus
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149836 , vital:38887 , https://doi.org/10.3389/fmars.2020.00071
- Description: On 1 March 2019, the United Nations (UN) General Assembly (New York) declared 2021–2030 the “UN Decade on Ecosystem Restoration.” This call to action has the purpose of recognizing the need to massively accelerate global restoration of degraded ecosystems, to fight the climate heating crisis, enhance food security, provide clean water and protect biodiversity on the planet. The scale of restoration will be key; for example, the Bonn Challenge has the goal to restore 350 million km2 (almost the size of India) of degraded terrestrial ecosystems by 2030. However, international support for restoration of “blue” coastal ecosystems, which provide an impressive array of benefits to people, has lagged. Only the Global Mangrove Alliance (https://mangrovealliance.org/) comes close to the Bonn Challenge, with the aim of increasing the global area of mangroves by 20% by 2030. However, mangrove scientists have reservations about this target, voicing concerns that it is unrealistic and may prompt inappropriate practices in attempting to reach this target (Lee et al., 2019). The decade of ecosystem restoration declaration also coincides with the UN Decade of Ocean Science for Sustainable Development, which aims to reverse deterioration in ocean health. If executed in a holistic and coordinated manner, signatory nations could stand to deliver on both these UN calls to action.
- Full Text:
- Date Issued: 2020
- Authors: Waltham, Nathan J , Elliott, Michael , Lee, Shing Yip , Lovelock, Catherine , Duarte, Carlos M , Buelow, Christina , Simenstad, Charles , Nagelkerken, Ivan , Claassens, Louw , Wen, Colin K-C , Barletta, Mario , Connolly, Rod M , Gillies, Chris , Mitsch, William J , Ogburn, Matthew B , Purandare, Jemma , Possingham, Hugh , Sheaves, Marcus
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/149836 , vital:38887 , https://doi.org/10.3389/fmars.2020.00071
- Description: On 1 March 2019, the United Nations (UN) General Assembly (New York) declared 2021–2030 the “UN Decade on Ecosystem Restoration.” This call to action has the purpose of recognizing the need to massively accelerate global restoration of degraded ecosystems, to fight the climate heating crisis, enhance food security, provide clean water and protect biodiversity on the planet. The scale of restoration will be key; for example, the Bonn Challenge has the goal to restore 350 million km2 (almost the size of India) of degraded terrestrial ecosystems by 2030. However, international support for restoration of “blue” coastal ecosystems, which provide an impressive array of benefits to people, has lagged. Only the Global Mangrove Alliance (https://mangrovealliance.org/) comes close to the Bonn Challenge, with the aim of increasing the global area of mangroves by 20% by 2030. However, mangrove scientists have reservations about this target, voicing concerns that it is unrealistic and may prompt inappropriate practices in attempting to reach this target (Lee et al., 2019). The decade of ecosystem restoration declaration also coincides with the UN Decade of Ocean Science for Sustainable Development, which aims to reverse deterioration in ocean health. If executed in a holistic and coordinated manner, signatory nations could stand to deliver on both these UN calls to action.
- Full Text:
- Date Issued: 2020
Drought, change and resilience in South Africa's arid and semi-arid rangelands
- Authors: Vetter, Susan M
- Date: 2009
- Language: English
- Type: Article
- Identifier: vital:6557 , http://hdl.handle.net/10962/d1006017
- Description: Droughts can have serious ecological and economic consequences and will pose an increasing challenge to rangeiand users as the global climate is changing. Finding ways to reduce ecological and economic impacts of drought should thus be a major research thrust. Resilience, defined as the amount of perturbation a social or ecological system can absorb without shifting to a qualitatively different state, has emerged as a prominent concept in ecosystem ecology and more recently as a conceptual framework for understanding and managing complex social-ecological systems. This paper discusses the application and relevance of resilience to understanding and managing ecosystem change, and enhancing the capacity of land users to adapt to droughts. Drought can trigger vegetation change and factors such as grazing management can influence the likelihood of such transitions. Drought can cause differential mortality of perennial plants and this could provide an opportunity for rangeland restoration by opening up establishment sites for desirable species. The capacity of land users to cope with drought is influenced by the resilience of their agro-ecosystems, the diversity of livelihood options, access to resources and institutional support. By these criteria, current agricultural development approaches in South Africa, particularly in communal rangelands and areas of land reform, are unlikely to enhance land users' resilience to drought and other perturbations.
- Full Text:
- Date Issued: 2009
- Authors: Vetter, Susan M
- Date: 2009
- Language: English
- Type: Article
- Identifier: vital:6557 , http://hdl.handle.net/10962/d1006017
- Description: Droughts can have serious ecological and economic consequences and will pose an increasing challenge to rangeiand users as the global climate is changing. Finding ways to reduce ecological and economic impacts of drought should thus be a major research thrust. Resilience, defined as the amount of perturbation a social or ecological system can absorb without shifting to a qualitatively different state, has emerged as a prominent concept in ecosystem ecology and more recently as a conceptual framework for understanding and managing complex social-ecological systems. This paper discusses the application and relevance of resilience to understanding and managing ecosystem change, and enhancing the capacity of land users to adapt to droughts. Drought can trigger vegetation change and factors such as grazing management can influence the likelihood of such transitions. Drought can cause differential mortality of perennial plants and this could provide an opportunity for rangeland restoration by opening up establishment sites for desirable species. The capacity of land users to cope with drought is influenced by the resilience of their agro-ecosystems, the diversity of livelihood options, access to resources and institutional support. By these criteria, current agricultural development approaches in South Africa, particularly in communal rangelands and areas of land reform, are unlikely to enhance land users' resilience to drought and other perturbations.
- Full Text:
- Date Issued: 2009
NMR structural elucidation of channaine, an unusual alkaloid from Sceletium tortuosum:
- Veale, Clinton G L, Chen, Weiyang, Chaudhary, Sushil, Kituyi, Sarah N, Isaacs, Michelle, Hoppe, Heinrich C, Edkins, Adrienne L, Combrinck, Sandra, Mehari, Bewketu, Viljoen, Alvaro
- Authors: Veale, Clinton G L , Chen, Weiyang , Chaudhary, Sushil , Kituyi, Sarah N , Isaacs, Michelle , Hoppe, Heinrich C , Edkins, Adrienne L , Combrinck, Sandra , Mehari, Bewketu , Viljoen, Alvaro
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/164345 , vital:41110 , DOI: 10.1016/j.phytol.2017.11.018
- Description: Chemical interrogation of the Sceletium genus and Amaryllidaceae family of plants has yielded a diverse array of aryl-hydroindole containing alkaloids. Included in this class is channaine, which was tentatively identified, without comprehensive structural elucidation from Sceletium tortuosum in 1957. Following its isolation from S. strictum, the structure of channaine was eventually resolved by X-ray crystallographic analysis, which revealed an unusual cage-like ring structure at the interface of two aryl-hydroindole subunits. However, since this report in 1978, channaine has not re-appeared in the literature. In this letter, the full NMR characterisation of channaine, isolated from S. tortuosum collected from St Helena in the Western Cape Province of South Africa, is reported for the first time.
- Full Text:
- Date Issued: 2018
- Authors: Veale, Clinton G L , Chen, Weiyang , Chaudhary, Sushil , Kituyi, Sarah N , Isaacs, Michelle , Hoppe, Heinrich C , Edkins, Adrienne L , Combrinck, Sandra , Mehari, Bewketu , Viljoen, Alvaro
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/164345 , vital:41110 , DOI: 10.1016/j.phytol.2017.11.018
- Description: Chemical interrogation of the Sceletium genus and Amaryllidaceae family of plants has yielded a diverse array of aryl-hydroindole containing alkaloids. Included in this class is channaine, which was tentatively identified, without comprehensive structural elucidation from Sceletium tortuosum in 1957. Following its isolation from S. strictum, the structure of channaine was eventually resolved by X-ray crystallographic analysis, which revealed an unusual cage-like ring structure at the interface of two aryl-hydroindole subunits. However, since this report in 1978, channaine has not re-appeared in the literature. In this letter, the full NMR characterisation of channaine, isolated from S. tortuosum collected from St Helena in the Western Cape Province of South Africa, is reported for the first time.
- Full Text:
- Date Issued: 2018
Facile synthesis and biological evaluation of assorted indolyl-3-amides and esters from a single, stable carbonyl nitrile intermediate
- Veale, Clinton G L, Edkins, Adrienne L, de la Mare, Jo-Anne, de Kock, Carmen, Smith, Peter J, Khanye, Setshaba D
- Authors: Veale, Clinton G L , Edkins, Adrienne L , de la Mare, Jo-Anne , de Kock, Carmen , Smith, Peter J , Khanye, Setshaba D
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66221 , vital:28919 , https://doi.org/10.1016/j.tetlet.2015.02.090
- Description: publisher version , The synthesis of biologically relevant amides and esters is routinely conducted under complex reaction conditions or requires the use of additional catalysts in order to generate sensitive electrophilic species for attack by a nucleophile. Here we present the synthesis of different indolic esters and amides from indolyl-3-carbonyl nitrile, without the requirement of anhydrous reaction conditions or catalysts. Additionally, we screened these compounds for potential in vitro antimalarial and anticancer activity, revealing 1H-indolyl-3-carboxylic acid 3-(indolyl-3-carboxamide)aminobenzyl ester to have moderate activity against both lines.
- Full Text: false
- Date Issued: 2015
- Authors: Veale, Clinton G L , Edkins, Adrienne L , de la Mare, Jo-Anne , de Kock, Carmen , Smith, Peter J , Khanye, Setshaba D
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66221 , vital:28919 , https://doi.org/10.1016/j.tetlet.2015.02.090
- Description: publisher version , The synthesis of biologically relevant amides and esters is routinely conducted under complex reaction conditions or requires the use of additional catalysts in order to generate sensitive electrophilic species for attack by a nucleophile. Here we present the synthesis of different indolic esters and amides from indolyl-3-carbonyl nitrile, without the requirement of anhydrous reaction conditions or catalysts. Additionally, we screened these compounds for potential in vitro antimalarial and anticancer activity, revealing 1H-indolyl-3-carboxylic acid 3-(indolyl-3-carboxamide)aminobenzyl ester to have moderate activity against both lines.
- Full Text: false
- Date Issued: 2015
Education, ethics and values : A response to Peter Blaze Corcoran’s keynote address, EEASA 2003
- Authors: Van Harmelen, U
- Date: 2003
- Language: English
- Type: Article
- Identifier: vital:6099 , http://hdl.handle.net/10962/d1008663
- Description: This paper is written in response to the Keynote Adress on the Earth Charter presented by Peter Blaze Corcoran at the EEASA 2003 Conference in Namibia. It draws attention to the significance of ethical debates in education and emphasises the need for careful attention to the way in which educators approach values education. In particular the paper considers the Earth Charter critically, and notes that while there is much value in the principles of the Earth Charter for guiding educational practice, educators should also consider some of the dilemmas of simply appropriating univeral ethical frameworks to guide practice.
- Full Text:
- Date Issued: 2003
- Authors: Van Harmelen, U
- Date: 2003
- Language: English
- Type: Article
- Identifier: vital:6099 , http://hdl.handle.net/10962/d1008663
- Description: This paper is written in response to the Keynote Adress on the Earth Charter presented by Peter Blaze Corcoran at the EEASA 2003 Conference in Namibia. It draws attention to the significance of ethical debates in education and emphasises the need for careful attention to the way in which educators approach values education. In particular the paper considers the Earth Charter critically, and notes that while there is much value in the principles of the Earth Charter for guiding educational practice, educators should also consider some of the dilemmas of simply appropriating univeral ethical frameworks to guide practice.
- Full Text:
- Date Issued: 2003
Introduction to Philosoph/Elementary Logic: PHL 112
- Authors: Van der Nest, M , Olivier, A
- Date: 2011-06
- Language: English
- Type: Examination paper
- Identifier: vital:18209 , http://hdl.handle.net/10353/d1011199
- Description: Introduction to Philosoph/Elementary Logic: PHL 112, examination June 2011.
- Full Text: false
- Date Issued: 2011-06
- Authors: Van der Nest, M , Olivier, A
- Date: 2011-06
- Language: English
- Type: Examination paper
- Identifier: vital:18209 , http://hdl.handle.net/10353/d1011199
- Description: Introduction to Philosoph/Elementary Logic: PHL 112, examination June 2011.
- Full Text: false
- Date Issued: 2011-06
Mercantile Law: LML 322E
- Authors: Van Coller, A , Phosa, M
- Date: 2009-11
- Subjects: Mercantile law
- Language: English
- Type: Examination paper
- Identifier: vital:17391 , http://hdl.handle.net/10353/d1009860
- Description: Mercantile Law: LML 322E, November Examination Paper 2009
- Full Text: false
- Date Issued: 2009-11
- Authors: Van Coller, A , Phosa, M
- Date: 2009-11
- Subjects: Mercantile law
- Language: English
- Type: Examination paper
- Identifier: vital:17391 , http://hdl.handle.net/10353/d1009860
- Description: Mercantile Law: LML 322E, November Examination Paper 2009
- Full Text: false
- Date Issued: 2009-11
GIS for Decision Support: GIS 503
- Authors: Tyson, C , Thompson, M
- Date: 2009-11
- Language: English
- Type: Examination paper
- Identifier: vital:17919 , http://hdl.handle.net/10353/d1011166
- Description: GIS for Decision Support: GIS 503, Honours examination November 2009.
- Full Text: false
- Date Issued: 2009-11
- Authors: Tyson, C , Thompson, M
- Date: 2009-11
- Language: English
- Type: Examination paper
- Identifier: vital:17919 , http://hdl.handle.net/10353/d1011166
- Description: GIS for Decision Support: GIS 503, Honours examination November 2009.
- Full Text: false
- Date Issued: 2009-11