In vitro investigation of the anti-hyperglycemic and chemical composition of Heteromorpha arborescens (Spreng.) Cham leaf extracts used in the management of diabetes mellitus
- Abifarin, Taiwo Oluwafunmilola https://orcid.org/00000003-4994-4638
- Authors: Abifarin, Taiwo Oluwafunmilola https://orcid.org/00000003-4994-4638
- Date: 2021-09
- Subjects: Diabetes
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/22798 , vital:52760
- Description: Diabetes mellitus is currently a major threat all over the world. It is a chronic disorder characterized by elevated blood glucose levels and disturbance in carbohydrate, fat and protein metabolism which often times leads to several complications such as, atherosclerosis, diabetic nephropathy, retinopathy and neuropathy. Due to the side effects associated with synthetic oral hypoglycemic drugs, herbal remedies have become the alternative in the management of diabetes mellitus. Heteromorpha arborescens is one of the many plants used as herbal remedies for the management of diabetes mellitus in South Africa. In addition, the roots, barks and leaves are used in other parts of Southern Africa for the treatment of mental problems, asthma, cough, dysentery and tuberculosis. The roots are fed to malnourished children in Botswana and Swaziland. However, despite the high medicinal importance, there is little or no scientificinformation to prove this claim. Therefore, the basis of this study is to determine the chemical composition as well as perform and invitro investigation of the antihyperglycemic potential of H. arborescens leaf extracts to provide information that could validate the ethno-medicinal claims for the use of this plant in the management of diabetes mellitus. Phytochemical contents and antioxidant activity of the leaf extracts were determined. Phytochemical analysis of the acetone, ethanol, aqueous and blanched extracts of H. arborescens leaves indicated that the total phenol content of the extracts ranged between 15.10 mg GAE/g- 42.50 mg QAE/g, proanthocyanidin, 459-8402.1 mg QE/g and the flavonoid content, 109.24- 235.79 mg QE/g. In addition, alkaloids (7.65percent) and saponin (25.33percent) were present in significantamounts. Based on the IC50 values, the ethanol extract exhibited the highest total antioxidant activity (0.0125 mg/mL) with highest inhibition against DPPH and ABTS radicals (0.06 and 0.049 mg/mL respectively). Relatively high antioxidant activity may be attributed to the polyphenolic contents which possess hypoglycemic potentials. Minimum Inhibitory Concentrations (MIC) of H. arborescens leaf extracts against Bacillus pumilus, Staphylococcus epidermidis, Staphylococcus aureus, Escherichia coli and Klebselia pneumoniae was also determined and results indicated considerable antibacterial activity in the acetone, ethanol and blanched extracts with MIC values ranging from 1.563-12.5 mg/mL; however, the aqueous extract was inactive against all the bacteria strains. The antibacterial activity of the leaf extracts could be advantageous against diabetic related infections. The cytotoxicity, anti-obesity and antidiabetic potentials of blanched, aqueous and ethanol extracts of Heteromorpha arborescens (Spreng.) Cham leaves were also investigated. The results revealed that both ethanol and aqueous extracts indicated considerable inhibition against α-glucosidase (IC50 of 627.29 ± 4.33 μg/mL and 576.46 ± 3.21 μg/mL respectively) while the blanched extract showed weak α- glucosidase inhibition (IC50; 855.38 ± 4.29 μg/mL). The aqueous extract showed the best α- amylase inhibition (IC50; 583.74 ± 5.87 μg/mL) among the assessed extracts. However, weak α- amylase inhibition was observed in the ethanol (IC50; 724.60 ± 4.33 μg/mL) and blanched extracts (IC50; 791.63 ± 3.76 μg/mL) of H. arborescens leaves. Some level of glucose utilization in both C3A and L6 cells was also observed for the aqueous and ethanol extracts which may be attributed to the relatively lower toxicity levels present in them, however, glucose utilization was very weak for the blanched extract, which may be due to higher level of cytotoxicity it possessed. Relatively weak lipase inhibition was observed for the ethanol (IC50; 699.3 ± 1.33 μg/mL), aqueous (IC50; 811.52 ± 3.52 μg/mL) and blanched extract (IC50; 1152.7 ± 4.61 μg/mL) as compared to orlistat (IC50; 56.88 ± 0.11 μg/mL). However, there was no reasonable reduction in lipid accumulation observed in all the extract treated cells. The results obtained suggest that H.arborescens leaf extracts can serve as a potential tool for the development of new strategies for the treatment of diabetes and obesity. However, further analysis is required to ascertain its anti- obesity potential. Also, caution should be taken in the use of the plant at high concentrations in order to ensure safety and efficacy. Analyses were also carried out to determine the nutritional and antinutritional constituents of the plant for possible inclusion in the diet of diabetic patients. Proximate analysis revealed the presence of 8.5 percent total ash, 4.92 percent crude fat, 8.41 percent moisture, 15.74 percent crude protein, 21.48 percent crude fiber, 40.95 percent carbohydrates and 271.04 kcal/100g energy value. Mineral analysis showed that H. arborescens leaves are very rich in K, Ca, and Fe. Considerable amounts of Mg, Mn, Na, P, Cu and Zn were also present. Vitamin analysis showed that the plant has a high content of vitamins A, C and E. The anti-nutrients evaluated were phytate, oxalate, saponin, and alkaloids, all of which were below toxic levels except for saponin which was observed in moderately high level. This study revealed that H. arborescens leaves are a good source of nutrients and mineral elements, (with low anti-nutrient content) that are highly beneficial to human health especially in diabetic individuals, therefore, encouraging its possible inclusion as a vegetable. Essential oil composition of fresh Heteromorphaarborescens leaves were also determined by Solvent-Free-Microwave-Extraction (SFME) and Hydrodistillation (HD) methods and the compositions of both mehods were compared in terms of their chemical compositions, yield, CO2 emission and energy consumption. Solvent Free Microwave extraction method indicated higher oil yield of 0.7 mL/200 g (0.35 percent) as compared to 0.59 mL/200 g (0.295 percent), lower energy consumption and CO2 emission as compared to the hydrodistillation method. In conclusion, H. arborescens leaves indicated considerable potential efficacy in the management for diabetes mellitus and may require further structural elucidation and characterization in order to identify the bioactive constituents. , Thesis (PhD) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Abifarin, Taiwo Oluwafunmilola https://orcid.org/00000003-4994-4638
- Date: 2021-09
- Subjects: Diabetes
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/22798 , vital:52760
- Description: Diabetes mellitus is currently a major threat all over the world. It is a chronic disorder characterized by elevated blood glucose levels and disturbance in carbohydrate, fat and protein metabolism which often times leads to several complications such as, atherosclerosis, diabetic nephropathy, retinopathy and neuropathy. Due to the side effects associated with synthetic oral hypoglycemic drugs, herbal remedies have become the alternative in the management of diabetes mellitus. Heteromorpha arborescens is one of the many plants used as herbal remedies for the management of diabetes mellitus in South Africa. In addition, the roots, barks and leaves are used in other parts of Southern Africa for the treatment of mental problems, asthma, cough, dysentery and tuberculosis. The roots are fed to malnourished children in Botswana and Swaziland. However, despite the high medicinal importance, there is little or no scientificinformation to prove this claim. Therefore, the basis of this study is to determine the chemical composition as well as perform and invitro investigation of the antihyperglycemic potential of H. arborescens leaf extracts to provide information that could validate the ethno-medicinal claims for the use of this plant in the management of diabetes mellitus. Phytochemical contents and antioxidant activity of the leaf extracts were determined. Phytochemical analysis of the acetone, ethanol, aqueous and blanched extracts of H. arborescens leaves indicated that the total phenol content of the extracts ranged between 15.10 mg GAE/g- 42.50 mg QAE/g, proanthocyanidin, 459-8402.1 mg QE/g and the flavonoid content, 109.24- 235.79 mg QE/g. In addition, alkaloids (7.65percent) and saponin (25.33percent) were present in significantamounts. Based on the IC50 values, the ethanol extract exhibited the highest total antioxidant activity (0.0125 mg/mL) with highest inhibition against DPPH and ABTS radicals (0.06 and 0.049 mg/mL respectively). Relatively high antioxidant activity may be attributed to the polyphenolic contents which possess hypoglycemic potentials. Minimum Inhibitory Concentrations (MIC) of H. arborescens leaf extracts against Bacillus pumilus, Staphylococcus epidermidis, Staphylococcus aureus, Escherichia coli and Klebselia pneumoniae was also determined and results indicated considerable antibacterial activity in the acetone, ethanol and blanched extracts with MIC values ranging from 1.563-12.5 mg/mL; however, the aqueous extract was inactive against all the bacteria strains. The antibacterial activity of the leaf extracts could be advantageous against diabetic related infections. The cytotoxicity, anti-obesity and antidiabetic potentials of blanched, aqueous and ethanol extracts of Heteromorpha arborescens (Spreng.) Cham leaves were also investigated. The results revealed that both ethanol and aqueous extracts indicated considerable inhibition against α-glucosidase (IC50 of 627.29 ± 4.33 μg/mL and 576.46 ± 3.21 μg/mL respectively) while the blanched extract showed weak α- glucosidase inhibition (IC50; 855.38 ± 4.29 μg/mL). The aqueous extract showed the best α- amylase inhibition (IC50; 583.74 ± 5.87 μg/mL) among the assessed extracts. However, weak α- amylase inhibition was observed in the ethanol (IC50; 724.60 ± 4.33 μg/mL) and blanched extracts (IC50; 791.63 ± 3.76 μg/mL) of H. arborescens leaves. Some level of glucose utilization in both C3A and L6 cells was also observed for the aqueous and ethanol extracts which may be attributed to the relatively lower toxicity levels present in them, however, glucose utilization was very weak for the blanched extract, which may be due to higher level of cytotoxicity it possessed. Relatively weak lipase inhibition was observed for the ethanol (IC50; 699.3 ± 1.33 μg/mL), aqueous (IC50; 811.52 ± 3.52 μg/mL) and blanched extract (IC50; 1152.7 ± 4.61 μg/mL) as compared to orlistat (IC50; 56.88 ± 0.11 μg/mL). However, there was no reasonable reduction in lipid accumulation observed in all the extract treated cells. The results obtained suggest that H.arborescens leaf extracts can serve as a potential tool for the development of new strategies for the treatment of diabetes and obesity. However, further analysis is required to ascertain its anti- obesity potential. Also, caution should be taken in the use of the plant at high concentrations in order to ensure safety and efficacy. Analyses were also carried out to determine the nutritional and antinutritional constituents of the plant for possible inclusion in the diet of diabetic patients. Proximate analysis revealed the presence of 8.5 percent total ash, 4.92 percent crude fat, 8.41 percent moisture, 15.74 percent crude protein, 21.48 percent crude fiber, 40.95 percent carbohydrates and 271.04 kcal/100g energy value. Mineral analysis showed that H. arborescens leaves are very rich in K, Ca, and Fe. Considerable amounts of Mg, Mn, Na, P, Cu and Zn were also present. Vitamin analysis showed that the plant has a high content of vitamins A, C and E. The anti-nutrients evaluated were phytate, oxalate, saponin, and alkaloids, all of which were below toxic levels except for saponin which was observed in moderately high level. This study revealed that H. arborescens leaves are a good source of nutrients and mineral elements, (with low anti-nutrient content) that are highly beneficial to human health especially in diabetic individuals, therefore, encouraging its possible inclusion as a vegetable. Essential oil composition of fresh Heteromorphaarborescens leaves were also determined by Solvent-Free-Microwave-Extraction (SFME) and Hydrodistillation (HD) methods and the compositions of both mehods were compared in terms of their chemical compositions, yield, CO2 emission and energy consumption. Solvent Free Microwave extraction method indicated higher oil yield of 0.7 mL/200 g (0.35 percent) as compared to 0.59 mL/200 g (0.295 percent), lower energy consumption and CO2 emission as compared to the hydrodistillation method. In conclusion, H. arborescens leaves indicated considerable potential efficacy in the management for diabetes mellitus and may require further structural elucidation and characterization in order to identify the bioactive constituents. , Thesis (PhD) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-09
The memory altar
- Alexander-McKenna, Hilary Jane
- Authors: Alexander-McKenna, Hilary Jane
- Date: 2022-04-07
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , South African fiction (English) 21st century , South African essays (English) 21st century , South African essays (English) History and criticism , South African fiction (English) History and criticism , Yuknavitch, Lidia Criticism and interpretation , American fiction Criticism and interpretation , COVID-19 (Disease) in literature
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/263533 , vital:53636
- Description: My thesis is a novella that casts a sideways glance at the real world that at times seems stranger than fiction. The novella is written as a work of realistic fiction, with a plot, characters, timelines and location placed in present time, reflecting real current events. My work is strongly influenced by writers such as Ivan Vladislavić whose Portrait with Keys uses a slice of life narrative voice that observes overlays of public and private realities; Marguerite Duras’ use of cinematic storytelling and deeply personal exposure in The Lover and Yann Andréa Steiner; Kate Zambreno’s depiction of inner chaos against the chaos of an anonymous city in Green Girl; Otessa Moshfegh who makes the minutiae of the day-to-day seem significant in My Year of Rest and Relaxation; and Samuel Beckett’s finely crafted streams of consciousness, in his works of prose and drama, revealing the intimate perspectives of insiders. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
- Authors: Alexander-McKenna, Hilary Jane
- Date: 2022-04-07
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , South African fiction (English) 21st century , South African essays (English) 21st century , South African essays (English) History and criticism , South African fiction (English) History and criticism , Yuknavitch, Lidia Criticism and interpretation , American fiction Criticism and interpretation , COVID-19 (Disease) in literature
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/263533 , vital:53636
- Description: My thesis is a novella that casts a sideways glance at the real world that at times seems stranger than fiction. The novella is written as a work of realistic fiction, with a plot, characters, timelines and location placed in present time, reflecting real current events. My work is strongly influenced by writers such as Ivan Vladislavić whose Portrait with Keys uses a slice of life narrative voice that observes overlays of public and private realities; Marguerite Duras’ use of cinematic storytelling and deeply personal exposure in The Lover and Yann Andréa Steiner; Kate Zambreno’s depiction of inner chaos against the chaos of an anonymous city in Green Girl; Otessa Moshfegh who makes the minutiae of the day-to-day seem significant in My Year of Rest and Relaxation; and Samuel Beckett’s finely crafted streams of consciousness, in his works of prose and drama, revealing the intimate perspectives of insiders. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
An inquiry into how Inter Press Service Africa makes alternative news from the Global South
- Authors: Chiwota, Elijah
- Date: 2021-10-29
- Subjects: Inter Press Service. Regional Centre for Africa , Workshop on the New World Information and Communication Order (1980 : Geneva, Switzerland) , Sustainable Development Goals Fund , Mass media Political aspects , Radicalism and the press , Mass media and globalization , Hegemony Political aspects , Counter hegemony
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192203 , vital:45205
- Description: An inquiry into how Inter Press Service (IPS) Africa makes alternative news from the Global South, is a study of a news agency that seeks to reverse the flows of information which predominantly comes from the Global North and by doing so carries the interests of the Global North (Boyd-Barrett, 2003). IPS was founded in 1964 by an international co-operative of journalists in the aftermath of the Cuban Revolution. At the same time, struggles for decolonization were at their peak in Africa and Asia. IPS promotes journalism for South-South co-operation and horizontal communication -- ideas that coincidentally found resonance in the debates for the New World Information and Communication Order (NWICO) that took place under the auspices of the United Nations Scientific and Cultural Organization (UNESCO) in 1980 (MacBride, 1980). As a regional centre of the IPS and a news agency of the Global South, IPS Africa is an alternative to international news agencies whose reports on Africa are characterised by representations of the other with a narrow focus on natural disasters, poverty, disease, and conflict. To counter this, IPS Africa developed alternative ways of news making from the Global South that focuses on highlighting the United Nations Sustainable Development Goals (SDGs) as one of the strategies to end poverty and promote sustainable development and to recognize the centrality of global partnerships for sustainable development. IPS African stories are written by local journalists who are familiar with the context under which they report. These stories can be described using the lenses of radical media content. IPS Africa is a not-for-profit news agency that makes news based on its organizational themes. Some of the stories emanate from reporters and editors who investigate development issues in their communities and link these to global events and developments. The study draws on Atton (2001) model of alternative and radical media to identify characteristics that include radical content and news values. A social realist approach is used in the study and the qualitative methods used are the analysis of documents, in-depth interviews, and textual analysis. The findings conclude that although a non-profit, IPS Africa can be described as a hybrid media organization in that it is a traditional news agency, with a management structure with board members, who contract freelance journalists to write copy. However, more meaning is found in the radical content of its stories. Despite being firmly rooted in its mission of “telling Africa’s untold stories,” the news agency has insufficient human and financial resources. Consequently, it faces sustainability and viability problems because of its over-reliance on external support through donor funds. , Thesis (MA) -- Faculty of Humanities, Journalsim and Media Studies, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Chiwota, Elijah
- Date: 2021-10-29
- Subjects: Inter Press Service. Regional Centre for Africa , Workshop on the New World Information and Communication Order (1980 : Geneva, Switzerland) , Sustainable Development Goals Fund , Mass media Political aspects , Radicalism and the press , Mass media and globalization , Hegemony Political aspects , Counter hegemony
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192203 , vital:45205
- Description: An inquiry into how Inter Press Service (IPS) Africa makes alternative news from the Global South, is a study of a news agency that seeks to reverse the flows of information which predominantly comes from the Global North and by doing so carries the interests of the Global North (Boyd-Barrett, 2003). IPS was founded in 1964 by an international co-operative of journalists in the aftermath of the Cuban Revolution. At the same time, struggles for decolonization were at their peak in Africa and Asia. IPS promotes journalism for South-South co-operation and horizontal communication -- ideas that coincidentally found resonance in the debates for the New World Information and Communication Order (NWICO) that took place under the auspices of the United Nations Scientific and Cultural Organization (UNESCO) in 1980 (MacBride, 1980). As a regional centre of the IPS and a news agency of the Global South, IPS Africa is an alternative to international news agencies whose reports on Africa are characterised by representations of the other with a narrow focus on natural disasters, poverty, disease, and conflict. To counter this, IPS Africa developed alternative ways of news making from the Global South that focuses on highlighting the United Nations Sustainable Development Goals (SDGs) as one of the strategies to end poverty and promote sustainable development and to recognize the centrality of global partnerships for sustainable development. IPS African stories are written by local journalists who are familiar with the context under which they report. These stories can be described using the lenses of radical media content. IPS Africa is a not-for-profit news agency that makes news based on its organizational themes. Some of the stories emanate from reporters and editors who investigate development issues in their communities and link these to global events and developments. The study draws on Atton (2001) model of alternative and radical media to identify characteristics that include radical content and news values. A social realist approach is used in the study and the qualitative methods used are the analysis of documents, in-depth interviews, and textual analysis. The findings conclude that although a non-profit, IPS Africa can be described as a hybrid media organization in that it is a traditional news agency, with a management structure with board members, who contract freelance journalists to write copy. However, more meaning is found in the radical content of its stories. Despite being firmly rooted in its mission of “telling Africa’s untold stories,” the news agency has insufficient human and financial resources. Consequently, it faces sustainability and viability problems because of its over-reliance on external support through donor funds. , Thesis (MA) -- Faculty of Humanities, Journalsim and Media Studies, 2021
- Full Text:
- Date Issued: 2021-10-29
Knowledge and attitude towards mastitis, culling and mortality among dairy farmworkers, and factors associated with culling and mortality among dairy cattle in the Eastern Cape Province, South Africa
- Authors: Diniso, Yanga Simamkele
- Date: 2021-09
- Subjects: Food security , Dairying--Economic aspects , Milking
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20686 , vital:46425
- Description: Globally, food security is under threat from escalating population growth, new variants of diseases, climate change and livestock loss. Africa is vulnerable to food insecurity, with majority of the estimated 800 million suffering from hunger based in Africa. Intensification of production is a common strategy to counter the increasing demand for nutritional food to maintain and improve food security. The dairy industry is one of the leading agriculture sectors that has adopted intensification of production. The current study had two specific objectives; the first objective was to evaluate the dairy farmworkers’ knowledge and attitude towards mastitis, culling, and mortality in the southern part of the Eastern Cape Province. The data was collected from 106 dairy farm workers of different farm hierarchy in 5 out of 6 districts using questionnaire. In cases whereby a majority correctly answered a question, a point was awarded and a zero for incorrectly answered questions by the majority. A less than 50 percent pass rate was considered a poor level of knowledge, 51-69 percent pass rate was considered an average level of knowledge, and anything higher than that considered a good level of knowledge. The majority of the participants (64.2 percent) indicated that they consume unpasteurised milk even though they know its risks. There was no association (P>0.05) between workplace position, educational level, work experience, and consumption of unpasteurised milk. This study found that participants had a deficient level of knowledge of mastitis causing pathogens by attaining a pass mark of 1.60 out of a possible 10 (16 percent), and educational level was significantly associated with knowledge of Escherichia coli, Staphylococcus aureus, and Streptococcus spp. However, the participants (64.9 percent) showed good knowledge of clinical signs of mastitis, and this was attributed to the regular mastitis detection with California Mastitis Test (CMT, 60.4 percent) and a strip cup (83.0 percent). The participants had varying perceptions and limited knowledge (28.3 percent pass rate) about the major contributing factors of culling and mortality. The lack of dairy training courses and minimal use of other sources of information such as the internet might contribute to this poor knowledge and perceptions. The second objective involved identifying and describing the factors responsible for culling and mortality in dairy farms in the Eastern Cape province, South Africa. The factors were grouped into seven (7) major factors namely lameness and poor growth (2.33 percent), reproduction problems (35.86 percent), health factors (6.72 percent), production factors (7.11 percent), udder-related factors (3.42 percent), voluntary culls (4.86 percent) and miscellaneous factors (26.03 percent). The most frequent reason for culling dairy cows was reproduction problems which was mainly made up of infertility (7.9 percent), reproductive failure (89.9 percent), and dystocia (1 percent). Miscellaneous factors which mainly consisted of indigenous breeds (8.2 percent), and age (2.7 percent) accounted for the second most prevalent factors for the culling of dairy cows. All the farms recorded stock-theft as part of involuntary culling and accounted for 3.6 percent dairy cows that were culled. Poor milk yield and health-related factors such as red-water (33.8 percent), milk-fever (23.3 percent), and heart-water (6.8 percent) were amongst the major factors responsible for the culling of dairy cows. There were 1774 (13.67 percent) dairy cows that died in the study farms from 2015 to 2019 and causes of death were not specified except for drowning (0.01 percent) and snake bite (1 percent). This study exposed a gap in knowledge about the causes of mastitis, culling and mortality among dairy farmworkers in the southern part of the Eastern Cape Province. Furthermore, this study provided with a baseline information on the leading causes of culling and mortality. There is a need for further research on strategies of enhancing the knowledge of dairy farmworkers about pathogens of mastitis and specific causes of culling and mortality to mitigate the challenge they pose to food security. , Thesis (MSc) (Animal Science) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Diniso, Yanga Simamkele
- Date: 2021-09
- Subjects: Food security , Dairying--Economic aspects , Milking
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20686 , vital:46425
- Description: Globally, food security is under threat from escalating population growth, new variants of diseases, climate change and livestock loss. Africa is vulnerable to food insecurity, with majority of the estimated 800 million suffering from hunger based in Africa. Intensification of production is a common strategy to counter the increasing demand for nutritional food to maintain and improve food security. The dairy industry is one of the leading agriculture sectors that has adopted intensification of production. The current study had two specific objectives; the first objective was to evaluate the dairy farmworkers’ knowledge and attitude towards mastitis, culling, and mortality in the southern part of the Eastern Cape Province. The data was collected from 106 dairy farm workers of different farm hierarchy in 5 out of 6 districts using questionnaire. In cases whereby a majority correctly answered a question, a point was awarded and a zero for incorrectly answered questions by the majority. A less than 50 percent pass rate was considered a poor level of knowledge, 51-69 percent pass rate was considered an average level of knowledge, and anything higher than that considered a good level of knowledge. The majority of the participants (64.2 percent) indicated that they consume unpasteurised milk even though they know its risks. There was no association (P>0.05) between workplace position, educational level, work experience, and consumption of unpasteurised milk. This study found that participants had a deficient level of knowledge of mastitis causing pathogens by attaining a pass mark of 1.60 out of a possible 10 (16 percent), and educational level was significantly associated with knowledge of Escherichia coli, Staphylococcus aureus, and Streptococcus spp. However, the participants (64.9 percent) showed good knowledge of clinical signs of mastitis, and this was attributed to the regular mastitis detection with California Mastitis Test (CMT, 60.4 percent) and a strip cup (83.0 percent). The participants had varying perceptions and limited knowledge (28.3 percent pass rate) about the major contributing factors of culling and mortality. The lack of dairy training courses and minimal use of other sources of information such as the internet might contribute to this poor knowledge and perceptions. The second objective involved identifying and describing the factors responsible for culling and mortality in dairy farms in the Eastern Cape province, South Africa. The factors were grouped into seven (7) major factors namely lameness and poor growth (2.33 percent), reproduction problems (35.86 percent), health factors (6.72 percent), production factors (7.11 percent), udder-related factors (3.42 percent), voluntary culls (4.86 percent) and miscellaneous factors (26.03 percent). The most frequent reason for culling dairy cows was reproduction problems which was mainly made up of infertility (7.9 percent), reproductive failure (89.9 percent), and dystocia (1 percent). Miscellaneous factors which mainly consisted of indigenous breeds (8.2 percent), and age (2.7 percent) accounted for the second most prevalent factors for the culling of dairy cows. All the farms recorded stock-theft as part of involuntary culling and accounted for 3.6 percent dairy cows that were culled. Poor milk yield and health-related factors such as red-water (33.8 percent), milk-fever (23.3 percent), and heart-water (6.8 percent) were amongst the major factors responsible for the culling of dairy cows. There were 1774 (13.67 percent) dairy cows that died in the study farms from 2015 to 2019 and causes of death were not specified except for drowning (0.01 percent) and snake bite (1 percent). This study exposed a gap in knowledge about the causes of mastitis, culling and mortality among dairy farmworkers in the southern part of the Eastern Cape Province. Furthermore, this study provided with a baseline information on the leading causes of culling and mortality. There is a need for further research on strategies of enhancing the knowledge of dairy farmworkers about pathogens of mastitis and specific causes of culling and mortality to mitigate the challenge they pose to food security. , Thesis (MSc) (Animal Science) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09
Evaluation of bacteria laccase hybrid biosensor and application in the detection of phenolic contaminants in water
- Edoamodu, Chiedu Epiphany https://orcid.org/0000-0002-9254-3955
- Authors: Edoamodu, Chiedu Epiphany https://orcid.org/0000-0002-9254-3955
- Date: 2021-09
- Subjects: Laccase , Water -- Purification
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/22820 , vital:52802
- Description: The continuous outpour of aromatic pollutants in diverse groups, emanating from the industrial and domestic system due to population density, industrialisation and technological advancement is alarming. The increasing strength in wastewater discharge constitutes the main cause of the natural water pollution load, causing scarcity of potable water for consumption with an increasing health challenge. The physiochemical treatment approach has faced a series of limitations with little or no success. Hindrance to wastewater management can cause a point source contamination problem that might increase treatment cost and release a broad range of chemical contaminants in the environment. Hence, green, eco-friendly and cost-effective tools are imperative. The application of laccase has received much attention in bioremediation and bioprocessing matters owing to the oxidising capacity of a wide range of substrates. The process requires available molecular oxygen for its activation, releasing water as a by-product thus, establishing this research. This study was devised to examine the bioprocessing potentials of hybrid and amalgamated laccases extracted from the diverse environmental milieu of the Eastern Cape Province, South Africa. Bacteria producing laccase were isolated from marine sediment, cow dung, and wastewater samples via selective enrichment with some aromatic compounds. The axenic cultures were screened for laccase activity on various phenolic and non-phenolic substrates. The isolates were identified via molecular techniques and they belonged to the gammaproteobacteria and Bacilli classes under the following genera, Enterobacter and Bacillus. They were deposited in the NCBI database as Enterobacter asburiae ES1, Enterobacter sp. Kamsi, Enterobacter sp. AI1, and Bacillus sp. NU2 with the assigned accession number MN686602, MN686603, MN686605, MN686607, respectively. Optimisation of the laccase production via one factor at a time technique (OFAT) from the four bacteria species showed more enzyme yield in all lignocellulosic agro-waste media. However, wheat bran and mandarin peel maximally enhanced laccase production. In addition, xylose, galactose, fructose, and sorbitol were the best carbon sources utilised while (NH₄)₂SO8, KNO3 and NaNO3 were noted as the best nitrogen sources employed. Laccase yields were increased at pH 4 and 5, at temperatures 45 and 55 o C, and at 50 and 100 rpm, and precisely, at day eight of the incubation period. Further purification of the crude laccase yielded a purification fold of 4.18, 4.39, 2.78, 8.11, and the SDS-PAGE analysis showed a molecular size of 90, 55, 75 and 50 kDa for ES1, Kamsi, AI1, and NU2 laccases, respectively. The characterised purified laccase demonstrated polyextremotolerant potentials. The laccases were active through a wide temperature regime (30-90 o C) with maximum activity at 50 o C (ES1/AI1 and Kamsi/NU2) 60 o C (AI1), 70 o C (ES1, Kamsi, NU2); and were stable at 60 o C (ES1, AI1, NU2), 70 o C (ES1/AI1), 80 o C (Kamsi and Kamsi/NU2). Also, the laccases remained active through pH 3 - 8 and optimal at pH 4 (AI1, NU2), pH 5 (Kamsi, ES1/AI1), pH 7 (ES1), pH 8 (Kamsi/NU2), and the individual stability was measured at pH 4 (Kamsi, NU2), pH 5 (AI1), pH 6 (ES1), pH 7 (Kamsi/NU2), pH 10 (ES1/AI1). The purified laccases were either enhanced or left unchanged by a variable concentration of metallic salts, inhibitors, chelating agents and organic solvents. Clearly, the activities of the laccase were enhanced when pre-incubated with 1, 3, and 6 mm of CuCl2, FeCl3, MgCl2, ZnCl2 and AgCl, and 1, 2, 3 mm of Triton x-100, PMSF, EDTA, Tween 20, and NaCl. Additionally, 20, 30, and 10 percent v/v of acetone and DMSO were prominent organic solvents that also stimulated both the hybrid and amalgamated laccase activity. The gene of the purified laccases targeted showed a clear band size of 690 bp for the Enterobacter species laccases and 775 bp for the laccase from Bacillus sp. The protein sequence was deposited in NCBI database with the assigned accession numbers, MW251989, MW25990, MW251992, and MW251994 for ES1, Kamsi, AI1, and NU2 laccases, respectively. The optimised pH and temperature parameter examined on the decolourising potential of the bacteria laccases showed an effective dye removal on the five synthetic dyes (Congo Red (CR), Methyl Orange (MO), Malachite Green (MG), Reactive Blue 4 (RB4), Ramazol Brilliant Blue R (RBBR)) applied. The purified laccases were successfully immobilised in Na-alginate with cca. 88.49, 70.91, 76.04, 76.13, 90.07, and 91.99 laccase yield for the hybrid (ES1, ES1, Kamsi, AI1, NU2) and amalgamated (ES1/AI1 and Kamsi/NU2) laccases. The immobilised laccases were able to retain an average activity of 32 – 52 percent after eight dye decolourising cycles, exhibiting strong catalytic activity than the free laccases. Nonetheless, no significant difference was examined between the hybrid and amalgamated laccase activity. Also, the immobilised laccases were shown to be more efficient in biotechnological application than the free laccases. The result suggests that immobilising an enzyme in a carrier matrix served effectively as the remediation approach than the hybrid and the amalgamation of the free enzymes. Also, the application of lignocellulosic waste served as a cheaper substrate for commercial production of laccase and could help s in promoting es the biotechnology application and the bioeconomy. , Thesis (PhD) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Edoamodu, Chiedu Epiphany https://orcid.org/0000-0002-9254-3955
- Date: 2021-09
- Subjects: Laccase , Water -- Purification
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/22820 , vital:52802
- Description: The continuous outpour of aromatic pollutants in diverse groups, emanating from the industrial and domestic system due to population density, industrialisation and technological advancement is alarming. The increasing strength in wastewater discharge constitutes the main cause of the natural water pollution load, causing scarcity of potable water for consumption with an increasing health challenge. The physiochemical treatment approach has faced a series of limitations with little or no success. Hindrance to wastewater management can cause a point source contamination problem that might increase treatment cost and release a broad range of chemical contaminants in the environment. Hence, green, eco-friendly and cost-effective tools are imperative. The application of laccase has received much attention in bioremediation and bioprocessing matters owing to the oxidising capacity of a wide range of substrates. The process requires available molecular oxygen for its activation, releasing water as a by-product thus, establishing this research. This study was devised to examine the bioprocessing potentials of hybrid and amalgamated laccases extracted from the diverse environmental milieu of the Eastern Cape Province, South Africa. Bacteria producing laccase were isolated from marine sediment, cow dung, and wastewater samples via selective enrichment with some aromatic compounds. The axenic cultures were screened for laccase activity on various phenolic and non-phenolic substrates. The isolates were identified via molecular techniques and they belonged to the gammaproteobacteria and Bacilli classes under the following genera, Enterobacter and Bacillus. They were deposited in the NCBI database as Enterobacter asburiae ES1, Enterobacter sp. Kamsi, Enterobacter sp. AI1, and Bacillus sp. NU2 with the assigned accession number MN686602, MN686603, MN686605, MN686607, respectively. Optimisation of the laccase production via one factor at a time technique (OFAT) from the four bacteria species showed more enzyme yield in all lignocellulosic agro-waste media. However, wheat bran and mandarin peel maximally enhanced laccase production. In addition, xylose, galactose, fructose, and sorbitol were the best carbon sources utilised while (NH₄)₂SO8, KNO3 and NaNO3 were noted as the best nitrogen sources employed. Laccase yields were increased at pH 4 and 5, at temperatures 45 and 55 o C, and at 50 and 100 rpm, and precisely, at day eight of the incubation period. Further purification of the crude laccase yielded a purification fold of 4.18, 4.39, 2.78, 8.11, and the SDS-PAGE analysis showed a molecular size of 90, 55, 75 and 50 kDa for ES1, Kamsi, AI1, and NU2 laccases, respectively. The characterised purified laccase demonstrated polyextremotolerant potentials. The laccases were active through a wide temperature regime (30-90 o C) with maximum activity at 50 o C (ES1/AI1 and Kamsi/NU2) 60 o C (AI1), 70 o C (ES1, Kamsi, NU2); and were stable at 60 o C (ES1, AI1, NU2), 70 o C (ES1/AI1), 80 o C (Kamsi and Kamsi/NU2). Also, the laccases remained active through pH 3 - 8 and optimal at pH 4 (AI1, NU2), pH 5 (Kamsi, ES1/AI1), pH 7 (ES1), pH 8 (Kamsi/NU2), and the individual stability was measured at pH 4 (Kamsi, NU2), pH 5 (AI1), pH 6 (ES1), pH 7 (Kamsi/NU2), pH 10 (ES1/AI1). The purified laccases were either enhanced or left unchanged by a variable concentration of metallic salts, inhibitors, chelating agents and organic solvents. Clearly, the activities of the laccase were enhanced when pre-incubated with 1, 3, and 6 mm of CuCl2, FeCl3, MgCl2, ZnCl2 and AgCl, and 1, 2, 3 mm of Triton x-100, PMSF, EDTA, Tween 20, and NaCl. Additionally, 20, 30, and 10 percent v/v of acetone and DMSO were prominent organic solvents that also stimulated both the hybrid and amalgamated laccase activity. The gene of the purified laccases targeted showed a clear band size of 690 bp for the Enterobacter species laccases and 775 bp for the laccase from Bacillus sp. The protein sequence was deposited in NCBI database with the assigned accession numbers, MW251989, MW25990, MW251992, and MW251994 for ES1, Kamsi, AI1, and NU2 laccases, respectively. The optimised pH and temperature parameter examined on the decolourising potential of the bacteria laccases showed an effective dye removal on the five synthetic dyes (Congo Red (CR), Methyl Orange (MO), Malachite Green (MG), Reactive Blue 4 (RB4), Ramazol Brilliant Blue R (RBBR)) applied. The purified laccases were successfully immobilised in Na-alginate with cca. 88.49, 70.91, 76.04, 76.13, 90.07, and 91.99 laccase yield for the hybrid (ES1, ES1, Kamsi, AI1, NU2) and amalgamated (ES1/AI1 and Kamsi/NU2) laccases. The immobilised laccases were able to retain an average activity of 32 – 52 percent after eight dye decolourising cycles, exhibiting strong catalytic activity than the free laccases. Nonetheless, no significant difference was examined between the hybrid and amalgamated laccase activity. Also, the immobilised laccases were shown to be more efficient in biotechnological application than the free laccases. The result suggests that immobilising an enzyme in a carrier matrix served effectively as the remediation approach than the hybrid and the amalgamation of the free enzymes. Also, the application of lignocellulosic waste served as a cheaper substrate for commercial production of laccase and could help s in promoting es the biotechnology application and the bioeconomy. , Thesis (PhD) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-09
Factors influencing the adoption of mobile health monitoring and care systems by the elderly living at home in South Africa: a case of Buffalo City Metropolitan Municipality.
- Authors: Fotoyi, Yolande Odwa
- Date: 2021-09
- Subjects: Medical informatics , Wireless communication systems in medical care
- Language: English
- Type: Master's/ theses , text
- Identifier: http://hdl.handle.net/10353/20406 , vital:45662
- Description: The gradual increase of elderly people around the globe necessitates intensive dialogue amongst government, the healthcare sector and elderly communities as per MPAA 2002 resolutions. Literature identifies technology as the enabler to drive the facilitation of improved living conditions beginning with an affordable, accessible and integrated health information system (HIS). The attainment of a better quality of care to meet the elderly’s needs requires the re-engineering of current modalities. The diverse nature of South Africa is more suited to a people-based rather than a process-centric approach currently in existence. Access barriers, affordability, the digital divide, lack of government buy-in, and fragmented HIS are considered major impediments to adoption of mobile monitoring and care systems (MMCs) for the elderly’s healthcare. Given the complications brought about by the Covid-19 pandemic, the adoption of MMCs cannot be more pronounced. However, despite available literature regarding elderly issues in both developed and developing countries, the elderly plight has still not been considered a national priority. The main purpose of this research was to investigate why elderly people do not adopt MMCs to improve their quality of life, with MMC technologies as a general area of research. The main objective of the study was to develop critical success factors to improve the adoption of MMCs by the elderly living at home. This would potentially alleviate the burden on healthcare resources and also improve the elderly’s quality of life. Primary data collection took place from 21 February to 28 February 2020 in Buffalo City Metropolitan Municipality. Semi-structured interviews were conducted with 15 participants comprising one male and 14 females who represented the elderly Black, Coloured, Indian and White people. This qualitative research tool and purposive sampling method were chosen in order to fully capture the participants’ experiences in the home environment, which excluded those living in frail care or step-down facilities or state institutions. Despite the sample size being small and not being generalizable, it delivered rich information which provided a deeper understanding and fresh insights into the landscape of the elderly and their healthcare needs. The interviews were recorded, transcribed and analysed thematically. The study found that elderly communities are not entirely averse to adoption of MMCs but challenges like affordability and chronic shortage of technical skills prove to be impediments to adoption of MMCs for the elderly’s healthcare. The lack of standardisation and data governance pertaining to data sharing in HISs also serve to exacerbate the matter. The study, therefore, recommends collaborative engagements amongst government, business and the elderly to facilitate the availability of affordable and accessible ICT infrastructure for the elderly communities. Improved adoption of MMCs carry the potential benefit which emanates from the assumption of a pro-active role by the elderly and optimising available MMCs thus reducing strain and freeing-up healthcare workers to concentrate on core duties. The onus thus falls on the healthcare sector to revise the available strategies which seek to enhance the quality of life of the elderly people living in the home environment. , Thesis (MCom) (Information Systems) -- University of Fort Hare, 2021.
- Full Text:
- Date Issued: 2021-09
- Authors: Fotoyi, Yolande Odwa
- Date: 2021-09
- Subjects: Medical informatics , Wireless communication systems in medical care
- Language: English
- Type: Master's/ theses , text
- Identifier: http://hdl.handle.net/10353/20406 , vital:45662
- Description: The gradual increase of elderly people around the globe necessitates intensive dialogue amongst government, the healthcare sector and elderly communities as per MPAA 2002 resolutions. Literature identifies technology as the enabler to drive the facilitation of improved living conditions beginning with an affordable, accessible and integrated health information system (HIS). The attainment of a better quality of care to meet the elderly’s needs requires the re-engineering of current modalities. The diverse nature of South Africa is more suited to a people-based rather than a process-centric approach currently in existence. Access barriers, affordability, the digital divide, lack of government buy-in, and fragmented HIS are considered major impediments to adoption of mobile monitoring and care systems (MMCs) for the elderly’s healthcare. Given the complications brought about by the Covid-19 pandemic, the adoption of MMCs cannot be more pronounced. However, despite available literature regarding elderly issues in both developed and developing countries, the elderly plight has still not been considered a national priority. The main purpose of this research was to investigate why elderly people do not adopt MMCs to improve their quality of life, with MMC technologies as a general area of research. The main objective of the study was to develop critical success factors to improve the adoption of MMCs by the elderly living at home. This would potentially alleviate the burden on healthcare resources and also improve the elderly’s quality of life. Primary data collection took place from 21 February to 28 February 2020 in Buffalo City Metropolitan Municipality. Semi-structured interviews were conducted with 15 participants comprising one male and 14 females who represented the elderly Black, Coloured, Indian and White people. This qualitative research tool and purposive sampling method were chosen in order to fully capture the participants’ experiences in the home environment, which excluded those living in frail care or step-down facilities or state institutions. Despite the sample size being small and not being generalizable, it delivered rich information which provided a deeper understanding and fresh insights into the landscape of the elderly and their healthcare needs. The interviews were recorded, transcribed and analysed thematically. The study found that elderly communities are not entirely averse to adoption of MMCs but challenges like affordability and chronic shortage of technical skills prove to be impediments to adoption of MMCs for the elderly’s healthcare. The lack of standardisation and data governance pertaining to data sharing in HISs also serve to exacerbate the matter. The study, therefore, recommends collaborative engagements amongst government, business and the elderly to facilitate the availability of affordable and accessible ICT infrastructure for the elderly communities. Improved adoption of MMCs carry the potential benefit which emanates from the assumption of a pro-active role by the elderly and optimising available MMCs thus reducing strain and freeing-up healthcare workers to concentrate on core duties. The onus thus falls on the healthcare sector to revise the available strategies which seek to enhance the quality of life of the elderly people living in the home environment. , Thesis (MCom) (Information Systems) -- University of Fort Hare, 2021.
- Full Text:
- Date Issued: 2021-09
The escalation of gender war within post-colonial South African society: an interrogation of beauty’s gift by Sindiwe Magona, happiness is a four-letter word by Cynthia Jele and black widow society by Angela Makholwa
- Authors: Goremusandu, Tania
- Date: 2021-09
- Subjects: Women and literature -- Africa , Women in literature
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/21927 , vital:51843
- Description: The critical analysis of gender war in the African context is not a new venture but it is rather a significant discussion to the development of gender and feminist theories. The primary focus of this study is to investigate the limitations to empowerment that African women face at the hands of a post-colonial patriarchal society like South Africa, exacerbated by the oppression and subjugation employed by patriarchal and cultural norms. Thus, the research provides a comparative analysis of three contemporary novels by award winning South African women writers in African literature: Sindiwe Magona, Cynthia Jele and Angela Makholwa. These three dedicated women writers examine the different ways in which African patriarchy and culture oppress professional, educated women. Their work portray gender and / or female oppression and the stereotypes experienced by African women in the context of post-colonial, heavily patriarchal South African society. Therefore, this study interrogates the experience of South African women, as explored in the texts, revealing the literary expressions of gender oppression as well as the possibilities of empowerment. In addition, the texts are analysed through the lens of the Feminist literary criticism theory, Gender studies and African feminism. Through the examination offered by these theories, the study focuses on the experiences of South African women, as expressed by the female characters in the selected texts, through a critical analysis of female oppression and resistance and on the idea that gender is constructed socially and culturally in the African context. As this project reveals, the problem arising within post-colonial South African society is that women are still oppressed and are seen as passive and submissive. As a result, patriarchal perspectives combined with women’s economic dependence on men, make reaching self-actualization a challenging and even terrifying experience, and is often impossible for most women to achieve. Thus, there is a need to understand the experiences of these women so that effective and culturally sensitive interventions can be implemented. The emergence of these renowned female South African writers together with the emancipation of African countries from colonial supremacy has opened a space for women to compensate for and correct the stereotyped female images in African literature and in post-colonial societies. Most contemporary African writers such as Chimamanda Ngozi Adichie, Tsitsi Dangarembga, Neshani Andreas, Sindiwe Magona, Cynthia Jele and Angela Makholwa have shown that women are seeking empowerment and liberation. Therefore, this study seeks to highlight such experiences through its critical interrogation of the writings of selected South African women writers and the exploration of their gender-based themes in order to inform and or inspire women empowerment. It is intended to broaden and encourage further academic discussion in the fields of Feminism literary criticism, Gender studies and African feminism as well as women’s literature within the African context. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Goremusandu, Tania
- Date: 2021-09
- Subjects: Women and literature -- Africa , Women in literature
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/21927 , vital:51843
- Description: The critical analysis of gender war in the African context is not a new venture but it is rather a significant discussion to the development of gender and feminist theories. The primary focus of this study is to investigate the limitations to empowerment that African women face at the hands of a post-colonial patriarchal society like South Africa, exacerbated by the oppression and subjugation employed by patriarchal and cultural norms. Thus, the research provides a comparative analysis of three contemporary novels by award winning South African women writers in African literature: Sindiwe Magona, Cynthia Jele and Angela Makholwa. These three dedicated women writers examine the different ways in which African patriarchy and culture oppress professional, educated women. Their work portray gender and / or female oppression and the stereotypes experienced by African women in the context of post-colonial, heavily patriarchal South African society. Therefore, this study interrogates the experience of South African women, as explored in the texts, revealing the literary expressions of gender oppression as well as the possibilities of empowerment. In addition, the texts are analysed through the lens of the Feminist literary criticism theory, Gender studies and African feminism. Through the examination offered by these theories, the study focuses on the experiences of South African women, as expressed by the female characters in the selected texts, through a critical analysis of female oppression and resistance and on the idea that gender is constructed socially and culturally in the African context. As this project reveals, the problem arising within post-colonial South African society is that women are still oppressed and are seen as passive and submissive. As a result, patriarchal perspectives combined with women’s economic dependence on men, make reaching self-actualization a challenging and even terrifying experience, and is often impossible for most women to achieve. Thus, there is a need to understand the experiences of these women so that effective and culturally sensitive interventions can be implemented. The emergence of these renowned female South African writers together with the emancipation of African countries from colonial supremacy has opened a space for women to compensate for and correct the stereotyped female images in African literature and in post-colonial societies. Most contemporary African writers such as Chimamanda Ngozi Adichie, Tsitsi Dangarembga, Neshani Andreas, Sindiwe Magona, Cynthia Jele and Angela Makholwa have shown that women are seeking empowerment and liberation. Therefore, this study seeks to highlight such experiences through its critical interrogation of the writings of selected South African women writers and the exploration of their gender-based themes in order to inform and or inspire women empowerment. It is intended to broaden and encourage further academic discussion in the fields of Feminism literary criticism, Gender studies and African feminism as well as women’s literature within the African context. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2021
- Full Text:
- Date Issued: 2021-09
Evaluation of medicinal potential of Boophone disticha (L.f.) Herb. used by the indigenous people in the Raymond Mhlaba Municipality Eastern Cape
- Authors: Gwayi, Yamkela
- Date: 2021-09
- Subjects: Bulbs (Plants) , Bulbs (Plant anatomy)
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20612 , vital:46375
- Description: Boophone disticha (L.f.) Herb. is a bulbous plant native to southern African areas of the continent and spreads to tropical Africa. The plant has been noted in literature for its high toxicity and has a long lineage of its use in traditional medicine for the treatment of various diseases. Due to high demand in the conventional trade market, the plant's conservation status has been shown to be declining. The plant has been reported to cause human poisoning, which can lead to death, but the plant is still administered by an indigenous community to treat various diseases. This study investigated the therapeutic potential of B. disticha used by the people of Raymond Mhlaba municipality to show and verify its use in traditional medicine and how it can be used as a possible drug ingredient. This study was also set out to investigate the anti-mycobacterial activity of the plant for the first time for the B. disticha growing in the Eastern Cape region of South Africa. The phytochemical analysis of B. disticha was carried out on four different plant parts (i.e., roots, leaves, bulb inner and outer scales) and the plant was extracted using methanol and distilled water. The qualitative phytochemical analysis displayed the presence of tannins, flavonoids, phenols and alkaloids in all plant parts for both extraction solvents. Anthraquinones were absent in all the plant extracts. The detected phytochemicals (tannins, flavonoids, phenols and alkaloids) were quantified. The roots had the highest phytochemical content for methanol extract for each phytochemical tested [439.67±1.53 mg/g (QE) flavonoids, 2414.67±1.53 mg/g (GAE) phenols and 527.33±2.08 mg/g (GAE) alkaloids] compared to all the plant parts. Methanol extracts from B. disticha revealed highest phenolic contents (2414.67±1.53 mg/g GAE) for the roots, 1395.33±2.52 mg/g (GAE) for the bulb inner scales, 1560±1 mg/g (GAE) for the leaves and 1550.7±18.9 mg/g (GAE) for the bulb outer scales). The total flavonoid content of the bulb outer scales aqueous extract was not detected. The presence of significant amounts of phytochemical compounds indicates that B. disticha has a higher medicinal value and can be extensively investigated to extract bioactive ingredients that are useful to the society, and that could be sold for higher production than using synthetic drugs with side effects. The antimicrobial activity of B. disticha extracts (methanol and distilled water) was evaluated using micro-dilution bioassay in 96-well micro-plates against nine disease-causing bacterial strains (5 Gram-negative and 4 Gram-positive) and three fungal isolates. The results revealed that methanol and aqueous extract of B. disticha demonstrated very good activity, with Gram-positive strains being more sensitive than Gram-negative ones. Boophone disticha aqueous extracts displayed the best activity against Staphylococcus aureus with MIC and MBC values ranging from 0.39 to 0.78 mg/ml. The methanolic extract of B. disticha leaves and outer scales of bulb displayed good activity against Klebsiella pneumoniae at MIC 0.78 mg/ml. The methanolic extract of B. disticha bulb outer scales also displayed good inhibition against Proteus vulgaris at MIC 0.78 mg/ml, with the root extract exhibiting activity against Shigella flexineri (MIC value of 0.078 mg/ml). Concerning antifungal activity, B. disticha extracts showed very poor inhibition properties against the fungal isolates. Anti-mycobacterium potential of B. disticha extracts (methanol and distilled water) was evaluated using micro-dilution bioassay in 96-well microtiter plates. The plant parts tested were the roots, bulb inner scales, leaves and the bulb outer scales. The highest activity against Mycobacterium tuberculosis was observed with the root methanol extract at MIC 0.78 mg/ml. The anti-inflammatory properties of B. disticha were investigated using the 5-lypoxygenase (5- LOX) assay. The overall anti-inflammatory activity results for the B. disticha extracts were poor; at low concentrations, the plant displayed negative results. The leaves methanol extracts did show little activity at 0.4 mg/ml. , Thesis (MSc) (Botany) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Gwayi, Yamkela
- Date: 2021-09
- Subjects: Bulbs (Plants) , Bulbs (Plant anatomy)
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20612 , vital:46375
- Description: Boophone disticha (L.f.) Herb. is a bulbous plant native to southern African areas of the continent and spreads to tropical Africa. The plant has been noted in literature for its high toxicity and has a long lineage of its use in traditional medicine for the treatment of various diseases. Due to high demand in the conventional trade market, the plant's conservation status has been shown to be declining. The plant has been reported to cause human poisoning, which can lead to death, but the plant is still administered by an indigenous community to treat various diseases. This study investigated the therapeutic potential of B. disticha used by the people of Raymond Mhlaba municipality to show and verify its use in traditional medicine and how it can be used as a possible drug ingredient. This study was also set out to investigate the anti-mycobacterial activity of the plant for the first time for the B. disticha growing in the Eastern Cape region of South Africa. The phytochemical analysis of B. disticha was carried out on four different plant parts (i.e., roots, leaves, bulb inner and outer scales) and the plant was extracted using methanol and distilled water. The qualitative phytochemical analysis displayed the presence of tannins, flavonoids, phenols and alkaloids in all plant parts for both extraction solvents. Anthraquinones were absent in all the plant extracts. The detected phytochemicals (tannins, flavonoids, phenols and alkaloids) were quantified. The roots had the highest phytochemical content for methanol extract for each phytochemical tested [439.67±1.53 mg/g (QE) flavonoids, 2414.67±1.53 mg/g (GAE) phenols and 527.33±2.08 mg/g (GAE) alkaloids] compared to all the plant parts. Methanol extracts from B. disticha revealed highest phenolic contents (2414.67±1.53 mg/g GAE) for the roots, 1395.33±2.52 mg/g (GAE) for the bulb inner scales, 1560±1 mg/g (GAE) for the leaves and 1550.7±18.9 mg/g (GAE) for the bulb outer scales). The total flavonoid content of the bulb outer scales aqueous extract was not detected. The presence of significant amounts of phytochemical compounds indicates that B. disticha has a higher medicinal value and can be extensively investigated to extract bioactive ingredients that are useful to the society, and that could be sold for higher production than using synthetic drugs with side effects. The antimicrobial activity of B. disticha extracts (methanol and distilled water) was evaluated using micro-dilution bioassay in 96-well micro-plates against nine disease-causing bacterial strains (5 Gram-negative and 4 Gram-positive) and three fungal isolates. The results revealed that methanol and aqueous extract of B. disticha demonstrated very good activity, with Gram-positive strains being more sensitive than Gram-negative ones. Boophone disticha aqueous extracts displayed the best activity against Staphylococcus aureus with MIC and MBC values ranging from 0.39 to 0.78 mg/ml. The methanolic extract of B. disticha leaves and outer scales of bulb displayed good activity against Klebsiella pneumoniae at MIC 0.78 mg/ml. The methanolic extract of B. disticha bulb outer scales also displayed good inhibition against Proteus vulgaris at MIC 0.78 mg/ml, with the root extract exhibiting activity against Shigella flexineri (MIC value of 0.078 mg/ml). Concerning antifungal activity, B. disticha extracts showed very poor inhibition properties against the fungal isolates. Anti-mycobacterium potential of B. disticha extracts (methanol and distilled water) was evaluated using micro-dilution bioassay in 96-well microtiter plates. The plant parts tested were the roots, bulb inner scales, leaves and the bulb outer scales. The highest activity against Mycobacterium tuberculosis was observed with the root methanol extract at MIC 0.78 mg/ml. The anti-inflammatory properties of B. disticha were investigated using the 5-lypoxygenase (5- LOX) assay. The overall anti-inflammatory activity results for the B. disticha extracts were poor; at low concentrations, the plant displayed negative results. The leaves methanol extracts did show little activity at 0.4 mg/ml. , Thesis (MSc) (Botany) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09
Vulnerability assessment of wetland ecosystems to water demand, climate variability and land-use/cover change: The case of Die Vlei wetland, Eastern Cape province, South Africa
- Gwena, Kudzanai Rosebud https://orcid.org/0000-0002-1032-8937
- Authors: Gwena, Kudzanai Rosebud https://orcid.org/0000-0002-1032-8937
- Date: 2021-09
- Subjects: Water-supply , Climate change mitigation
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/22688 , vital:52656
- Description: Water scarcity is a major challenge in many different countries, particularly arid and or semi-arid like South Africa. Wetlands are one of the freshwater ecosystems that may assist in alleviating water scarcity because they are valuable not only as a water source for humans but also as an ecosystem of animals and plant species. However, wetlands have been experiencing rapid rates of vulnerability/risk due to alterations by population growth leading to enhanced water demand, climate variability, and human activities leading to land cover/land-use changes. Geographical Information Systems (GIS) and Remote Sensing (RS) are less financially taxing methods useful in studying water scarcity, as shown in this study. The study begins with a literature review presentation based on a desk study from predominantly academic publications and additional municipal and consultancy reports on the wetland ecosystem’s vulnerability/risk and focuses on applying GIS & RS in related studies. After that, the study conducts a vulnerability assessment using the Ramsar Convention’s wetland vulnerability assessment using the theoretical framework stages using GIS and RS technologies. The study hypothesizes that water demand, climate variability, and land-use/cover changes (LULC) are the tri-factor responsible for wetland vulnerability. It begins the assessment by first quantifying wetland water demand using the wetland water budget, ecosystem services and the Penman-Montheith-FAO (ETo) evapotranspiration index. Secondly, objectively representing climate variability on wetland vulnerability using trend analysis to measure rainfall and temperature variability. Thirdly, reconstructing LULC changes from multi-date remotely sensed SPOT imagery over ten years from 2007 to 2017 to identify and monitor impacts of trends. The vulnerability was assessed through a Principle Component Analysis (PCA) that identified relevant variables and Multi-Criteria Evaluation (MCE) to evaluate the wetland’s exposure. The study concludes that there is evidence of a possible increase in water demand whilst climate variability, which is estimated to have a 39% contribution to the wetland dynamics, is characterised by a decrease in precipitation and an increase in temperatures. Lastly, LULC trends showed a marked increase in domestic and commercial farming, and farming has been identified as a wetland stressor of note. , Thesis (MPhil) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Gwena, Kudzanai Rosebud https://orcid.org/0000-0002-1032-8937
- Date: 2021-09
- Subjects: Water-supply , Climate change mitigation
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/22688 , vital:52656
- Description: Water scarcity is a major challenge in many different countries, particularly arid and or semi-arid like South Africa. Wetlands are one of the freshwater ecosystems that may assist in alleviating water scarcity because they are valuable not only as a water source for humans but also as an ecosystem of animals and plant species. However, wetlands have been experiencing rapid rates of vulnerability/risk due to alterations by population growth leading to enhanced water demand, climate variability, and human activities leading to land cover/land-use changes. Geographical Information Systems (GIS) and Remote Sensing (RS) are less financially taxing methods useful in studying water scarcity, as shown in this study. The study begins with a literature review presentation based on a desk study from predominantly academic publications and additional municipal and consultancy reports on the wetland ecosystem’s vulnerability/risk and focuses on applying GIS & RS in related studies. After that, the study conducts a vulnerability assessment using the Ramsar Convention’s wetland vulnerability assessment using the theoretical framework stages using GIS and RS technologies. The study hypothesizes that water demand, climate variability, and land-use/cover changes (LULC) are the tri-factor responsible for wetland vulnerability. It begins the assessment by first quantifying wetland water demand using the wetland water budget, ecosystem services and the Penman-Montheith-FAO (ETo) evapotranspiration index. Secondly, objectively representing climate variability on wetland vulnerability using trend analysis to measure rainfall and temperature variability. Thirdly, reconstructing LULC changes from multi-date remotely sensed SPOT imagery over ten years from 2007 to 2017 to identify and monitor impacts of trends. The vulnerability was assessed through a Principle Component Analysis (PCA) that identified relevant variables and Multi-Criteria Evaluation (MCE) to evaluate the wetland’s exposure. The study concludes that there is evidence of a possible increase in water demand whilst climate variability, which is estimated to have a 39% contribution to the wetland dynamics, is characterised by a decrease in precipitation and an increase in temperatures. Lastly, LULC trends showed a marked increase in domestic and commercial farming, and farming has been identified as a wetland stressor of note. , Thesis (MPhil) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-09
An Investigation on the Clinical Experiences of Newly Qualified Professional Nurses in Hospital Facilities of the Alfred Nzo District Municipality in the Eastern Cape
- Authors: Hloba, Siyathemba Prince
- Date: 2021-00
- Subjects: Nurse practitioners
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7942 , vital:55856
- Description: The study aimed to explore and describe the clinical experiences of newly qualified professional nurses in hospital facilities of the Alfred Nzo District Municipality in the Eastern Cape. The newly qualified professional nurses may face difficulties in the hospital facilities when it comes to the execution of duties. The newly qualified professional nurses are expected to display knowledge, skills and to have a positive effect on patients, the relatives of patients and their colleagues to alleviate diseases. This challenge may create emotional distress if newly qualified professional nurses receive inadequate guidance from the senior staff members of the hospital facility. The objectives of this study were to explore and describe the clinical experiences of newly qualified professional nurses, to explore how the newly qualified professional nurses were affected emotionally by clinical experiences and to explore the support system to enhance the performance of the newly qualified professional nurses. A qualitative, explorative, descriptive and contextual design was used to explore and describe the experiences of the newly qualified professional nurses in hospital facilities of the Alfred Nzo District Municipality in the Eastern Cape. A purposive sampling of newly qualified professional nurses, with less than two years of experience after completing the community service in the clinical practice, was used. The data were collected through face-to-face and semi-structured interviews. The interviews were conducted until the data were saturated. A pilot study was done before the main study to prove the adequacy and suitability of the methods to conduct the main study. The participants‟ interviews and results of the pilot study were incorporated into the interviews and results of the main study. Tesch‟s method of thematic analysis and an independent coder were used to analyse the data and to draw meaning from the content. The study used Guba and Lincoln‟s criteria of measures to ensure trustworthiness, which included credibility, confirmability, dependability and transferability. Ethical standards were maintained throughout the study as the researcher complied with ethical principles, namely, respect for persons, beneficence, justice and autonomy. The key considerations to curb the spread of the Covid-19 pandemic, as stipulated by the World Health Organisation, were followed during the data collection. On data interpretation, three themes were developed with eight subthemes on the first theme, two subthemes on the second theme and three subthemes on the third theme. The research findings revealed that the participants experienced negative attitudes from colleagues and multidisciplinary team members. The shortage of staff and resources made participants feel ineffective in their work environment. Clinical exposure to different units and procedures in various units added value to the development of the participants. The recommendations were made with regards to three divisions. They were the hospital facilities‟ personnel, future nursing research personnel and nursing schools personnel. In hospital facilities, the recommendations included that all novice professional nurses should be made aware of the emotional impact at work. An annual plan for workshops and in-service training should be implemented. Professional counselling is required for the novice professionals who were exposed to Covid-19 isolation units. A need to increase staff coverage in the clinical units was identified as the workload is too big. Management is encouraged to be more sensitive about the newly employed nurses‟ challenges in their facilities and the most experienced nurses are encouraged to mentor and coach the novice nurses. In the future nursing research, recommendations included that more studies need to be conducted in South Africa and the Eastern Cape province to verify the findings of this research. A specific research study that will focus on the supportive needs of nurses in clinical facilities should be done institutionally to provide evidence-based practice. The research culture on the nurses‟ experiences in clinical facilities needs to become a norm. In nursing schools, the recommendations motivated that the nursing students should be exposed to all clinical units before completing the training xiv course. Further studies need to be conducted to evaluate the balance between theory and clinical learning on duly performance. The nursing education institutions should use quality improvement suggestion boxes for students to consider their experiences and opinions about their learning. Key words : clinical experiences, newly qualified professional nurses, Alfred Nzo district municipalities , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-00
- Authors: Hloba, Siyathemba Prince
- Date: 2021-00
- Subjects: Nurse practitioners
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7942 , vital:55856
- Description: The study aimed to explore and describe the clinical experiences of newly qualified professional nurses in hospital facilities of the Alfred Nzo District Municipality in the Eastern Cape. The newly qualified professional nurses may face difficulties in the hospital facilities when it comes to the execution of duties. The newly qualified professional nurses are expected to display knowledge, skills and to have a positive effect on patients, the relatives of patients and their colleagues to alleviate diseases. This challenge may create emotional distress if newly qualified professional nurses receive inadequate guidance from the senior staff members of the hospital facility. The objectives of this study were to explore and describe the clinical experiences of newly qualified professional nurses, to explore how the newly qualified professional nurses were affected emotionally by clinical experiences and to explore the support system to enhance the performance of the newly qualified professional nurses. A qualitative, explorative, descriptive and contextual design was used to explore and describe the experiences of the newly qualified professional nurses in hospital facilities of the Alfred Nzo District Municipality in the Eastern Cape. A purposive sampling of newly qualified professional nurses, with less than two years of experience after completing the community service in the clinical practice, was used. The data were collected through face-to-face and semi-structured interviews. The interviews were conducted until the data were saturated. A pilot study was done before the main study to prove the adequacy and suitability of the methods to conduct the main study. The participants‟ interviews and results of the pilot study were incorporated into the interviews and results of the main study. Tesch‟s method of thematic analysis and an independent coder were used to analyse the data and to draw meaning from the content. The study used Guba and Lincoln‟s criteria of measures to ensure trustworthiness, which included credibility, confirmability, dependability and transferability. Ethical standards were maintained throughout the study as the researcher complied with ethical principles, namely, respect for persons, beneficence, justice and autonomy. The key considerations to curb the spread of the Covid-19 pandemic, as stipulated by the World Health Organisation, were followed during the data collection. On data interpretation, three themes were developed with eight subthemes on the first theme, two subthemes on the second theme and three subthemes on the third theme. The research findings revealed that the participants experienced negative attitudes from colleagues and multidisciplinary team members. The shortage of staff and resources made participants feel ineffective in their work environment. Clinical exposure to different units and procedures in various units added value to the development of the participants. The recommendations were made with regards to three divisions. They were the hospital facilities‟ personnel, future nursing research personnel and nursing schools personnel. In hospital facilities, the recommendations included that all novice professional nurses should be made aware of the emotional impact at work. An annual plan for workshops and in-service training should be implemented. Professional counselling is required for the novice professionals who were exposed to Covid-19 isolation units. A need to increase staff coverage in the clinical units was identified as the workload is too big. Management is encouraged to be more sensitive about the newly employed nurses‟ challenges in their facilities and the most experienced nurses are encouraged to mentor and coach the novice nurses. In the future nursing research, recommendations included that more studies need to be conducted in South Africa and the Eastern Cape province to verify the findings of this research. A specific research study that will focus on the supportive needs of nurses in clinical facilities should be done institutionally to provide evidence-based practice. The research culture on the nurses‟ experiences in clinical facilities needs to become a norm. In nursing schools, the recommendations motivated that the nursing students should be exposed to all clinical units before completing the training xiv course. Further studies need to be conducted to evaluate the balance between theory and clinical learning on duly performance. The nursing education institutions should use quality improvement suggestion boxes for students to consider their experiences and opinions about their learning. Key words : clinical experiences, newly qualified professional nurses, Alfred Nzo district municipalities , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-00
Experiences of patients with cancer regarding decentralization of oncology services at a selected tertiary hospital in the Eastern Cape
- Authors: Jojo, Lumkile
- Date: 2021-09
- Subjects: Cancer -- Nursing
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26907 , vital:66080
- Description: Background: Cancer burden is a global public health concern. It is associated with high morbidities and mortalities worldwide. Over the past decade, there has been a constant increase in the incidence of cancer cases affecting mostly low-income countries and middle- income countries. South Africa as a middle-income country is also affected by this cancer rise. The limited access to oncology services contributed to the late presentation and late diagnosis. In the Eastern Cape, oncology services were previously offered in Port Elizabeth and East London only. Oncology unit was recently opened in Mthatha to decentralize oncology services in the province. The purpose of the study was to explore the experiences of patients with cancer regarding decentralization of oncology services at a public tertiary hospital in the Eastern Cape province of South Africa. Objectives were to describe experiences of patients with cancer regarding decentralization of oncology services at a public tertiary hospital in the Eastern Cape, and to describe the quality of oncology services provided by a public tertiary hospital in the Eastern Cape. Methods: a qualitative research approach with a descriptive, explorative, and contextual design was undertaken in this study, to get the perspective of the oncology healthcare service recipients on the decentralization of oncology services at a public tertiary hospital. An interview guide was used to get experiences of the cancer patients attending oncology clinic. Interviews were conducted to 19 participants on a one-to-one basis. With ethical consideration, all COVID-19 protocols were observed. All interviews were transcribed carefully against their audio-recordings. Field notes were also taken by the researcher on what was heard, observed, thought and experienced during the interview process. The concept of trustworthiness was used to ensure rigour throughout this study. Data was analysed by means of thematic analysis. Data was organized into themes using the Tesch’s approach to open coding in qualitative research. Results: seven themes emerged: 1) experience related to a high level of satisfaction with services provided and desired expectations, 2) waiting time, 3) availability of human and material resources, 4) attitude of health care workers, 5) appropriate treatment and care, 6) access to services, and 7) need for improved infrastructural facilities Many patients had positive experiences about decentralization of oncology services in the province. Most patients were happy about travelling short distances, a smaller number of days, using less money and the time it takes to see a doctor. They also expressed their satisfaction on the quality of oncology services rendered in the unit. The waiting times were acceptable, medicines available and staff had positive attitudes towards the patients. The study revealed that, there were complaints about infrastructure, poor hospital record keeping, and lack of resources. The themes which emanated from the recordings of the study showed that patients with cancer, attending oncology clinic at a public tertiary hospital had positive experiences in this decentralized oncology unit. The services rendered at the facility were of acceptable quality. Staff had positive attitude towards their patients. All patients were seen by the doctors within acceptable waiting time, and they all got their prescribed medication. Access to services was much improved in terms of distance, number of days travelled by patients to access the service and time taken to see the doctor for appointments. Conclusion: The hospital must improve its infrastructure, record keeping, security, and expand the services. Put more focus on cancer awareness programs. , Thesis (MPA) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Jojo, Lumkile
- Date: 2021-09
- Subjects: Cancer -- Nursing
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26907 , vital:66080
- Description: Background: Cancer burden is a global public health concern. It is associated with high morbidities and mortalities worldwide. Over the past decade, there has been a constant increase in the incidence of cancer cases affecting mostly low-income countries and middle- income countries. South Africa as a middle-income country is also affected by this cancer rise. The limited access to oncology services contributed to the late presentation and late diagnosis. In the Eastern Cape, oncology services were previously offered in Port Elizabeth and East London only. Oncology unit was recently opened in Mthatha to decentralize oncology services in the province. The purpose of the study was to explore the experiences of patients with cancer regarding decentralization of oncology services at a public tertiary hospital in the Eastern Cape province of South Africa. Objectives were to describe experiences of patients with cancer regarding decentralization of oncology services at a public tertiary hospital in the Eastern Cape, and to describe the quality of oncology services provided by a public tertiary hospital in the Eastern Cape. Methods: a qualitative research approach with a descriptive, explorative, and contextual design was undertaken in this study, to get the perspective of the oncology healthcare service recipients on the decentralization of oncology services at a public tertiary hospital. An interview guide was used to get experiences of the cancer patients attending oncology clinic. Interviews were conducted to 19 participants on a one-to-one basis. With ethical consideration, all COVID-19 protocols were observed. All interviews were transcribed carefully against their audio-recordings. Field notes were also taken by the researcher on what was heard, observed, thought and experienced during the interview process. The concept of trustworthiness was used to ensure rigour throughout this study. Data was analysed by means of thematic analysis. Data was organized into themes using the Tesch’s approach to open coding in qualitative research. Results: seven themes emerged: 1) experience related to a high level of satisfaction with services provided and desired expectations, 2) waiting time, 3) availability of human and material resources, 4) attitude of health care workers, 5) appropriate treatment and care, 6) access to services, and 7) need for improved infrastructural facilities Many patients had positive experiences about decentralization of oncology services in the province. Most patients were happy about travelling short distances, a smaller number of days, using less money and the time it takes to see a doctor. They also expressed their satisfaction on the quality of oncology services rendered in the unit. The waiting times were acceptable, medicines available and staff had positive attitudes towards the patients. The study revealed that, there were complaints about infrastructure, poor hospital record keeping, and lack of resources. The themes which emanated from the recordings of the study showed that patients with cancer, attending oncology clinic at a public tertiary hospital had positive experiences in this decentralized oncology unit. The services rendered at the facility were of acceptable quality. Staff had positive attitude towards their patients. All patients were seen by the doctors within acceptable waiting time, and they all got their prescribed medication. Access to services was much improved in terms of distance, number of days travelled by patients to access the service and time taken to see the doctor for appointments. Conclusion: The hospital must improve its infrastructure, record keeping, security, and expand the services. Put more focus on cancer awareness programs. , Thesis (MPA) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-09
Experiences of patients with cancer regarding decentralization of oncology services at a selected tertiary hospital in the Eastern Cape
- Authors: Jojo, Lumkile Wilmot
- Date: 2021-09
- Subjects: Cancer -- Patients , Oncology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23510 , vital:58074
- Description: Background: Cancer burden is a global public health concern. It is associated with high morbidities and mortalities worldwide. Over the past decade, there has been a constant increase in the incidence of cancer cases affecting mostly low-income countries and middle- income countries. South Africa as a middle-income country is also affected by this cancer rise. The limited access to oncology services contributed to the late presentation and late diagnosis. In the Eastern Cape, oncology services were previously offered in Port Elizabeth and East London only. Oncology unit was recently opened in Mthatha to decentralize oncology services in the province. The purpose of the study was to explore the experiences of patients with cancer regarding decentralization of oncology services at a public tertiary hospital in the Eastern Cape province of South Africa. Objectives were to describe experiences of patients with cancer regarding decentralization of oncology services at a public tertiary hospital in the Eastern Cape, and to describe the quality of oncology services provided by a public tertiary hospital in the Eastern Cape. Methods: a qualitative research approach with a descriptive, explorative, and contextual design was undertaken in this study, to get the perspective of the oncology healthcare service recipients on the decentralization of oncology services at a public tertiary hospital. An interview guide was used to get experiences of the cancer patients attending oncology clinic. Interviews were conducted to 19 participants on a one-to-one basis. With ethical consideration, all COVID-19 protocols were observed. All interviews were transcribed carefully against their audio-recordings. Field notes were also taken by the researcher on what was heard, observed, thought and experienced during the interview process. The concept of trustworthiness was used to ensure rigour throughout this study. Data was analysed by means of thematic analysis. Data was organized into themes using the Tesch’s approach to open coding in qualitative research. Results: seven themes emerged: 1) experience related to a high level of satisfaction with services provided and desired expectations, 2) waiting time, 3) availability of human and material resources, 4) attitude of health care workers, 5) appropriate treatment and care, 6) access to services, and 7) need for improved infrastructural facilities. Many patients had positive experiences about decentralization of oncology services in the province. Most patients were happy about travelling short distances, a smaller number of days, using less money and the time it takes to see a doctor. They also expressed their satisfaction on the quality of oncology services rendered in the unit. The waiting times were acceptable, medicines available and staff had positive attitudes towards the patients. The study revealed that, there were complaints about infrastructure, poor hospital record keeping, and lack of resources. The themes which emanated from the recordings of the study showed that patients with cancer, attending oncology clinic at a public tertiary hospital had positive experiences in this decentralized oncology unit. The services rendered at the facility were of acceptable quality. Staff had positive attitude towards their patients. All patients were seen by the doctors within acceptable waiting time, and they all got their prescribed medication. Access to services was much improved in terms of distance, number of days travelled by patients to access the service and time taken to see the doctor for appointments. Conclusion: The hospital must improve its infrastructure, record keeping, security, and expand the services. Put more focus on cancer awareness programs. , Thesis (MPA) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Jojo, Lumkile Wilmot
- Date: 2021-09
- Subjects: Cancer -- Patients , Oncology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23510 , vital:58074
- Description: Background: Cancer burden is a global public health concern. It is associated with high morbidities and mortalities worldwide. Over the past decade, there has been a constant increase in the incidence of cancer cases affecting mostly low-income countries and middle- income countries. South Africa as a middle-income country is also affected by this cancer rise. The limited access to oncology services contributed to the late presentation and late diagnosis. In the Eastern Cape, oncology services were previously offered in Port Elizabeth and East London only. Oncology unit was recently opened in Mthatha to decentralize oncology services in the province. The purpose of the study was to explore the experiences of patients with cancer regarding decentralization of oncology services at a public tertiary hospital in the Eastern Cape province of South Africa. Objectives were to describe experiences of patients with cancer regarding decentralization of oncology services at a public tertiary hospital in the Eastern Cape, and to describe the quality of oncology services provided by a public tertiary hospital in the Eastern Cape. Methods: a qualitative research approach with a descriptive, explorative, and contextual design was undertaken in this study, to get the perspective of the oncology healthcare service recipients on the decentralization of oncology services at a public tertiary hospital. An interview guide was used to get experiences of the cancer patients attending oncology clinic. Interviews were conducted to 19 participants on a one-to-one basis. With ethical consideration, all COVID-19 protocols were observed. All interviews were transcribed carefully against their audio-recordings. Field notes were also taken by the researcher on what was heard, observed, thought and experienced during the interview process. The concept of trustworthiness was used to ensure rigour throughout this study. Data was analysed by means of thematic analysis. Data was organized into themes using the Tesch’s approach to open coding in qualitative research. Results: seven themes emerged: 1) experience related to a high level of satisfaction with services provided and desired expectations, 2) waiting time, 3) availability of human and material resources, 4) attitude of health care workers, 5) appropriate treatment and care, 6) access to services, and 7) need for improved infrastructural facilities. Many patients had positive experiences about decentralization of oncology services in the province. Most patients were happy about travelling short distances, a smaller number of days, using less money and the time it takes to see a doctor. They also expressed their satisfaction on the quality of oncology services rendered in the unit. The waiting times were acceptable, medicines available and staff had positive attitudes towards the patients. The study revealed that, there were complaints about infrastructure, poor hospital record keeping, and lack of resources. The themes which emanated from the recordings of the study showed that patients with cancer, attending oncology clinic at a public tertiary hospital had positive experiences in this decentralized oncology unit. The services rendered at the facility were of acceptable quality. Staff had positive attitude towards their patients. All patients were seen by the doctors within acceptable waiting time, and they all got their prescribed medication. Access to services was much improved in terms of distance, number of days travelled by patients to access the service and time taken to see the doctor for appointments. Conclusion: The hospital must improve its infrastructure, record keeping, security, and expand the services. Put more focus on cancer awareness programs. , Thesis (MPA) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-09
Exploring how Grade 11 chemistry teachers make use of the periodic table of elements when mediating learning of writing and balancing chemical equations
- Kambeyo, Reginald Ndeshipanda
- Authors: Kambeyo, Reginald Ndeshipanda
- Date: 2021-10-29
- Subjects: Chemistry Study and teaching (Secondary) Namibia , Periodic table of the elements , Chemical equations Study and teaching (Secondary) Namibia , Chemistry teachers Attitudes Namibia , Pedagogical content knowledge , Topic-Specific Pedagogical Content Knowledge (TSPCK)
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/191986 , vital:45185
- Description: The periodic table of elements is central to the study of chemistry and other disciplines of science, yet Namibian learners do not perform satisfactorily in topics which require its use in answering questions. The purpose of this study, therefore, was to explore how Grade 11 chemistry teachers make use of the periodic table of elements to mediate the learning of writing and balancing chemical equations. The study was carried out with two chemistry teachers in two rural schools in the northern part of Namibia. It was underpinned by an interpretive paradigm, within which a qualitative case study approach was employed. Data were collected through in-depth interviews (semi-structured and stimulated recall interviews), observations, and participants’ group reflections. The latter afforded the participants and myself room to reflect and share ideas at the end of the data gathering process. I used Shulman’s Pedagogical Content Knowledge as my theoretical framework in this study and the data sets were analysed using the five Topic-Specific Pedagogical Content Knowledge (TSPCK) components adapted from Mavhunga and Rollnick. The findings revealed that teachers demonstrated positive attitudes towards the use of the periodic table of elements when teaching the writing and balancing of chemical equations. However, challenges regarding inadequate materials that hindered the teaching and learning process were observed. Another finding of this study was that teachers used a variety of mediation tools such as prior knowledge and appropriate representations to enhance learning. However, during lesson observations, the findings revealed that there was an imbalance in the knowledge of using easily accessible resources as opposed to what teachers had indicated during the semi-structured interviews. Nonetheless, teachers’ group reflections influenced them to analyse and improve their lessons. The study thus recommends that there is a need for continuing professional development for chemistry teachers so that teachers can be afforded opportunities and spaces to share subject matter knowledge, pedagogical content knowledge as well as easily accessible resources that they can use to enhance teaching of chemistry in their classrooms. , Thesis (MEd) -- Faculty of Education, Education, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Kambeyo, Reginald Ndeshipanda
- Date: 2021-10-29
- Subjects: Chemistry Study and teaching (Secondary) Namibia , Periodic table of the elements , Chemical equations Study and teaching (Secondary) Namibia , Chemistry teachers Attitudes Namibia , Pedagogical content knowledge , Topic-Specific Pedagogical Content Knowledge (TSPCK)
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/191986 , vital:45185
- Description: The periodic table of elements is central to the study of chemistry and other disciplines of science, yet Namibian learners do not perform satisfactorily in topics which require its use in answering questions. The purpose of this study, therefore, was to explore how Grade 11 chemistry teachers make use of the periodic table of elements to mediate the learning of writing and balancing chemical equations. The study was carried out with two chemistry teachers in two rural schools in the northern part of Namibia. It was underpinned by an interpretive paradigm, within which a qualitative case study approach was employed. Data were collected through in-depth interviews (semi-structured and stimulated recall interviews), observations, and participants’ group reflections. The latter afforded the participants and myself room to reflect and share ideas at the end of the data gathering process. I used Shulman’s Pedagogical Content Knowledge as my theoretical framework in this study and the data sets were analysed using the five Topic-Specific Pedagogical Content Knowledge (TSPCK) components adapted from Mavhunga and Rollnick. The findings revealed that teachers demonstrated positive attitudes towards the use of the periodic table of elements when teaching the writing and balancing of chemical equations. However, challenges regarding inadequate materials that hindered the teaching and learning process were observed. Another finding of this study was that teachers used a variety of mediation tools such as prior knowledge and appropriate representations to enhance learning. However, during lesson observations, the findings revealed that there was an imbalance in the knowledge of using easily accessible resources as opposed to what teachers had indicated during the semi-structured interviews. Nonetheless, teachers’ group reflections influenced them to analyse and improve their lessons. The study thus recommends that there is a need for continuing professional development for chemistry teachers so that teachers can be afforded opportunities and spaces to share subject matter knowledge, pedagogical content knowledge as well as easily accessible resources that they can use to enhance teaching of chemistry in their classrooms. , Thesis (MEd) -- Faculty of Education, Education, 2021
- Full Text:
- Date Issued: 2021-10-29
Malnutrition in children under the age of 5 years in a primary health care setting
- Kaswa, Ramprakash, Govender, Indiran, Rangiah, Selvandran, Nzaumvila, Doudou
- Authors: Kaswa, Ramprakash , Govender, Indiran , Rangiah, Selvandran , Nzaumvila, Doudou
- Date: 2021
- Subjects: Obesity Malnutrition Dietary supplements Article
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/7260 , vital:53106 , xlink:href="https://doi.org/10.4102/safp.v63i1.5337"
- Description: In this study, we outlined the types of malnutrition amongst children, the causes of malnutrition intervention at the primary health care level and some recommendations to alleviate childhood malnutrition in South Africa. Keywords: obesity; severe acute malnutrition; individual factors; community level factors; dietary intervention.
- Full Text:
- Date Issued: 2021
- Authors: Kaswa, Ramprakash , Govender, Indiran , Rangiah, Selvandran , Nzaumvila, Doudou
- Date: 2021
- Subjects: Obesity Malnutrition Dietary supplements Article
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/7260 , vital:53106 , xlink:href="https://doi.org/10.4102/safp.v63i1.5337"
- Description: In this study, we outlined the types of malnutrition amongst children, the causes of malnutrition intervention at the primary health care level and some recommendations to alleviate childhood malnutrition in South Africa. Keywords: obesity; severe acute malnutrition; individual factors; community level factors; dietary intervention.
- Full Text:
- Date Issued: 2021
Effect of grazing systems and age on enteric methane production and performance plus grazing system effect on ruminal fermentation parameters of Nguni and Bonsmara beef cows
- Authors: Kayima, Denis
- Date: 2021-09
- Subjects: Grazing , Pastures--Management , Ruminants--Feeding and feeds
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20583 , vital:46153
- Description: Beef breeds of cattle are predominantly raised through extensive grazing and produce the highest levels of enteric methane (CH4) through ruminal fermentation. The objective of this study was to evaluate the effect of breed, grazing, and age on enteric methane production and performance of beef cows as well as effect of breed and grazing system on ruminal fermentation parameters. Two separate studies were conducted; the first study evaluated the effect of grazing system, breed, and age on ruminal enteric methane production and performance of selected beef breeds. The second study evaluated the effect of the grazing system and breed on ruminal fermentation. In the first study, two breeds (Nguni and Bonsmara) raised under two grazing systems (communal and commercial) in a random complete block design were grouped into 3 age categories. Eighty-four cows aged between 24-120 months were randomly selected and grouped by age: group A (young adult cow, n = 7, 24-48 months old), group B (adult, n = 7, 60-80 months old), and group C (old adult, n = 7, 90-120 months) in either grazing system. Data were collected on methane production per day, body condition, and weight used to estimate dry matter intake (DMI), methane per DMI, and methane per body weight. In the second study, 40 cows of the same age group, parity, and physiological status were used. Ten cows per breed (Bonsmara and Nguni) in either grazing system (communal and commercial) were used in a random complete block design. Rumen fluid collection was done by the stomach tube method. Data were collected on ruminal ammonia-nitrogen (NH3-N), pH, Temperature, volatile fatty acids (VFAs). Older animals produced higher methane per head in the order of C > B > A; (P<0.0001). Performance parameters like Body condition score (BCS), body weight (BW), dry matter intake (DMI), and daily methane were higher (P<0.05) in Bonsmara. However, Methane per BW was higher in Nguni (P<0.05), and methane per DMI did not differ among breeds (P>0.05). Body condition, BW, and DMI were higher (P<0.05) in commercial grazing system. Contrary, daily methane production, methane production per DMI, and methane produced per BW were higher in communal grazing. In the second study, Ruminal NH3-N concentration ranged between 69.05 - 96.78 mg/L and was higher (P<0.05) in Nguni. It was also higher (P<0.05) in the commercial grazing system. Ruminal pH, temperature, total VFAs, and certain individual VFAs (iso-butyrate, valeric and iso-valeric) did not differ (P>0.05) among breeds and grazing systems. However, total VFAs were slightly lower in communal grazing (78.87 mmol/L) than commercial grazing (89.80 mmol/L). Acetate, propionate, butyrate proportions, and acetate to propionate ratio did not differ (P>0.05) among breeds but differed (P<0.05) between grazing systems. Acetate (P<0.05) and acetate to propionate ratio (P<0.05) were higher in the communal grazing system, while the reverse was true for propionate (P<0.05) and butyrate (P<0.05). Bonsmara produced more methane than Nguni under similar conditions, with Nguni uniquely producing more methane per BW, indicating host genetics influence. Communal animals and older animals produced more CH4 than commercial and younger cows regardless of the breed, indicating ruminal inefficiencies in very old cows. These results emphasize the idea that host genetics or breed, grazing system, and age influence methane output and performance. Hence, breeding strategies for hard-to-measure traits like methane production need to put all these factors into consideration. , Thesis (MSc) (Animal Science) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Kayima, Denis
- Date: 2021-09
- Subjects: Grazing , Pastures--Management , Ruminants--Feeding and feeds
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20583 , vital:46153
- Description: Beef breeds of cattle are predominantly raised through extensive grazing and produce the highest levels of enteric methane (CH4) through ruminal fermentation. The objective of this study was to evaluate the effect of breed, grazing, and age on enteric methane production and performance of beef cows as well as effect of breed and grazing system on ruminal fermentation parameters. Two separate studies were conducted; the first study evaluated the effect of grazing system, breed, and age on ruminal enteric methane production and performance of selected beef breeds. The second study evaluated the effect of the grazing system and breed on ruminal fermentation. In the first study, two breeds (Nguni and Bonsmara) raised under two grazing systems (communal and commercial) in a random complete block design were grouped into 3 age categories. Eighty-four cows aged between 24-120 months were randomly selected and grouped by age: group A (young adult cow, n = 7, 24-48 months old), group B (adult, n = 7, 60-80 months old), and group C (old adult, n = 7, 90-120 months) in either grazing system. Data were collected on methane production per day, body condition, and weight used to estimate dry matter intake (DMI), methane per DMI, and methane per body weight. In the second study, 40 cows of the same age group, parity, and physiological status were used. Ten cows per breed (Bonsmara and Nguni) in either grazing system (communal and commercial) were used in a random complete block design. Rumen fluid collection was done by the stomach tube method. Data were collected on ruminal ammonia-nitrogen (NH3-N), pH, Temperature, volatile fatty acids (VFAs). Older animals produced higher methane per head in the order of C > B > A; (P<0.0001). Performance parameters like Body condition score (BCS), body weight (BW), dry matter intake (DMI), and daily methane were higher (P<0.05) in Bonsmara. However, Methane per BW was higher in Nguni (P<0.05), and methane per DMI did not differ among breeds (P>0.05). Body condition, BW, and DMI were higher (P<0.05) in commercial grazing system. Contrary, daily methane production, methane production per DMI, and methane produced per BW were higher in communal grazing. In the second study, Ruminal NH3-N concentration ranged between 69.05 - 96.78 mg/L and was higher (P<0.05) in Nguni. It was also higher (P<0.05) in the commercial grazing system. Ruminal pH, temperature, total VFAs, and certain individual VFAs (iso-butyrate, valeric and iso-valeric) did not differ (P>0.05) among breeds and grazing systems. However, total VFAs were slightly lower in communal grazing (78.87 mmol/L) than commercial grazing (89.80 mmol/L). Acetate, propionate, butyrate proportions, and acetate to propionate ratio did not differ (P>0.05) among breeds but differed (P<0.05) between grazing systems. Acetate (P<0.05) and acetate to propionate ratio (P<0.05) were higher in the communal grazing system, while the reverse was true for propionate (P<0.05) and butyrate (P<0.05). Bonsmara produced more methane than Nguni under similar conditions, with Nguni uniquely producing more methane per BW, indicating host genetics influence. Communal animals and older animals produced more CH4 than commercial and younger cows regardless of the breed, indicating ruminal inefficiencies in very old cows. These results emphasize the idea that host genetics or breed, grazing system, and age influence methane output and performance. Hence, breeding strategies for hard-to-measure traits like methane production need to put all these factors into consideration. , Thesis (MSc) (Animal Science) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09
Capital flows and real exchange rate movement in South Africa
- Authors: Lindani, Sandiswa
- Date: 2021-09
- Subjects: Foreign exchange rates , Exchange rate pass-through , Capital movements
- Language: English
- Type: Master's/ theses , text
- Identifier: http://hdl.handle.net/10353/20417 , vital:45664
- Description: The neoclassical theory suggests that free flow of external capital should be equilibrating and thereby facilitating smoothening of an economy's consumption or production patterns. Based on this background, this study empirically examines the extent to which the different forms of capital flows amongst other variables influence the real exchange rate in South Africa for the period 1980 to 2019, using annual data. Estimation techniques employed include the Johansen Co-integration Approach and the Vector error correction model (VECM). The variables were found to be co-integrated, with six co-integrating vectors existing. The long-run results revealed that FPI has an appreciating effect on the exchange rate in South Africa. Based on the results, policy recommendations are suggested. , Thesis (MCom) (Economics) -- University of Fort Hare, 2021.
- Full Text:
- Date Issued: 2021-09
- Authors: Lindani, Sandiswa
- Date: 2021-09
- Subjects: Foreign exchange rates , Exchange rate pass-through , Capital movements
- Language: English
- Type: Master's/ theses , text
- Identifier: http://hdl.handle.net/10353/20417 , vital:45664
- Description: The neoclassical theory suggests that free flow of external capital should be equilibrating and thereby facilitating smoothening of an economy's consumption or production patterns. Based on this background, this study empirically examines the extent to which the different forms of capital flows amongst other variables influence the real exchange rate in South Africa for the period 1980 to 2019, using annual data. Estimation techniques employed include the Johansen Co-integration Approach and the Vector error correction model (VECM). The variables were found to be co-integrated, with six co-integrating vectors existing. The long-run results revealed that FPI has an appreciating effect on the exchange rate in South Africa. Based on the results, policy recommendations are suggested. , Thesis (MCom) (Economics) -- University of Fort Hare, 2021.
- Full Text:
- Date Issued: 2021-09
Characterisation of the ultramafic and carbonatite components of the Schiel Alkaline Complex in the Limpopo Province of South Africa
- Authors: Mahomed, Uzayr
- Date: 2021-10-29
- Subjects: Ultrabasic rocks South Africa Limpopo , Carbonatites South Africa Limpopo , Geology South Africa Limpopo , Mica South Africa Limpopo , Biotite South Africa Limpopo , Magmatism , Schiel Alkaline Complex , Phoscorite , Glimmerite
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/294768 , vital:57253
- Description: Owing to the poor documentation of the phoscorite-carbonatite association present in the Schiel Complex and the associated economic potential of other known phoscorite-bearing complexes, the Schiel Complex is widely thought to have similar economic potential. This complex is often compared to the lucrative Phalaborwa Complex, as it is thought to have crystallised from a common parental melt, with a similar age of emplacement. This study aims to provide clarity on the physical and chemical characterisation of the various rock types present in the Schiel Complex, with this study being the first petrological investigation based on fresh in-situ samples gathered from 3 borehole cores which were drilled by FOSKOR in the 1960s. The sampled sections of the ultramafics from the Schiel Complex are comprised of end-member rock compositions of either magmatic phoscorites or pyroxenites or metasomatic glimmerites, where gradational contacts between these various end-members produce rock varieties that contain characteristics of one or more end-member types. Carbonatite rocks are present as medium-grained, coarse-grained and banded calcio-carbonatite varieties where the carbonatite rocks are proposed as being the metasomatic medium for glimmerite production. Contrary to previous research, the structure of the ultramafic and carbonatite bodies are present as vein and veinlet structures which seem to originate from a single pipe-like body, from which these rock types intruded into the surrounding syenitic country-rock. Metasomatic alteration of the ultramafic sections of the Schiel Complex also show that the carbonatite rocks must have intruded after some ultramafic magmatism. The presence of the same minerals, with similar chemistries, in both the ultramafic and carbonatite rocks as well as similar REE chondrite-normalised plots show that the various rock types may have originated from a common parental magma, where the accumulation and crystallisation of minerals is the most likely factor in producing the various Schiel Complex rock varieties, causing silicate minerals to be present in the carbonate fraction of the magma, and carbonate minerals in the silicate fraction of the magma. Apatite is the expected rare earth element (REE) mineralising mineral in phoscorites, but is shown to be depleted in REE content in the Schiel Complex due to metasomatic fluid infiltration causing the scavenging and dissipation of REEs. These rocks have also crystallised containing no significant copper-bearing mineralisation, contrary to that which is seen in the Phalaborwa Complex. A comparison of mica minerals between the Schiel Complex rocks and the Phalaborwa Complex rocks show that the two complexes have undergone unique emplacement processes and should not be considered as sister complexes. Efforts to date the glimmerite and carbonatite rocks based on zircon grain U/Pb geochronology proved unsuccessful in constraining the current ages of emplacement provided by previous researchers, but rock relationships show that the current accepted sequence of events cannot be correct, providing scope for further research. This study provides an update on the chemical and physical characteristics, based on the only available sample suite of the ultramafic and carbonatite components, of the Schiel Complex, increasing the depth of documentation of these rare rock types and aiding in refuting some conclusions on the genesis, emplacement and evolution of the Schiel Complex proposed by previous research. , Thesis (MSc) -- Faculty of Science, Geology, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Mahomed, Uzayr
- Date: 2021-10-29
- Subjects: Ultrabasic rocks South Africa Limpopo , Carbonatites South Africa Limpopo , Geology South Africa Limpopo , Mica South Africa Limpopo , Biotite South Africa Limpopo , Magmatism , Schiel Alkaline Complex , Phoscorite , Glimmerite
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/294768 , vital:57253
- Description: Owing to the poor documentation of the phoscorite-carbonatite association present in the Schiel Complex and the associated economic potential of other known phoscorite-bearing complexes, the Schiel Complex is widely thought to have similar economic potential. This complex is often compared to the lucrative Phalaborwa Complex, as it is thought to have crystallised from a common parental melt, with a similar age of emplacement. This study aims to provide clarity on the physical and chemical characterisation of the various rock types present in the Schiel Complex, with this study being the first petrological investigation based on fresh in-situ samples gathered from 3 borehole cores which were drilled by FOSKOR in the 1960s. The sampled sections of the ultramafics from the Schiel Complex are comprised of end-member rock compositions of either magmatic phoscorites or pyroxenites or metasomatic glimmerites, where gradational contacts between these various end-members produce rock varieties that contain characteristics of one or more end-member types. Carbonatite rocks are present as medium-grained, coarse-grained and banded calcio-carbonatite varieties where the carbonatite rocks are proposed as being the metasomatic medium for glimmerite production. Contrary to previous research, the structure of the ultramafic and carbonatite bodies are present as vein and veinlet structures which seem to originate from a single pipe-like body, from which these rock types intruded into the surrounding syenitic country-rock. Metasomatic alteration of the ultramafic sections of the Schiel Complex also show that the carbonatite rocks must have intruded after some ultramafic magmatism. The presence of the same minerals, with similar chemistries, in both the ultramafic and carbonatite rocks as well as similar REE chondrite-normalised plots show that the various rock types may have originated from a common parental magma, where the accumulation and crystallisation of minerals is the most likely factor in producing the various Schiel Complex rock varieties, causing silicate minerals to be present in the carbonate fraction of the magma, and carbonate minerals in the silicate fraction of the magma. Apatite is the expected rare earth element (REE) mineralising mineral in phoscorites, but is shown to be depleted in REE content in the Schiel Complex due to metasomatic fluid infiltration causing the scavenging and dissipation of REEs. These rocks have also crystallised containing no significant copper-bearing mineralisation, contrary to that which is seen in the Phalaborwa Complex. A comparison of mica minerals between the Schiel Complex rocks and the Phalaborwa Complex rocks show that the two complexes have undergone unique emplacement processes and should not be considered as sister complexes. Efforts to date the glimmerite and carbonatite rocks based on zircon grain U/Pb geochronology proved unsuccessful in constraining the current ages of emplacement provided by previous researchers, but rock relationships show that the current accepted sequence of events cannot be correct, providing scope for further research. This study provides an update on the chemical and physical characteristics, based on the only available sample suite of the ultramafic and carbonatite components, of the Schiel Complex, increasing the depth of documentation of these rare rock types and aiding in refuting some conclusions on the genesis, emplacement and evolution of the Schiel Complex proposed by previous research. , Thesis (MSc) -- Faculty of Science, Geology, 2021
- Full Text:
- Date Issued: 2021-10-29
The adoption of the twin peaks model in the regulation of South African financial markets : a comparative analysis.
- Marange, Patience https://orcid.org/ 0000-0003-4405-2702
- Authors: Marange, Patience https://orcid.org/ 0000-0003-4405-2702
- Date: 2021-09
- Subjects: Financial services industry , Financial services industry--Law and legislation
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/21278 , vital:48175
- Description: Over two decades ago, a number of countries have changed their financial regulatory models. The growing complexity of financial products, the increasing challenge of regulating large financial conglomerates, and the repercussions of the 2008 Global Financial Crisis, amongst other factors, have made regulatory reform a key priority for many economies. A move towards the Twin Peaks model of financial regulation has been one of the trends in recent years. This model sees regulation split into two broad functions which are market conduct regulation and prudential regulation. South Africa adopted the Twin Peaks financial regulatory model in 2017 as a way of strengthening its financial regulatory model. By adopting the Twin Peaks model, South Africa has become the eighth and the first developing country to adopt the financial regulatory model. The adoption of the Twin Peaks financial regulatory model in South Africa was mainly inspired by the effects of the 2008 Global Financial Crisis. This study undertakes a comparison of the Twin Peaks model structure in South Africa with the structure of its counterparts, which are Australia, United Kingdom and the Netherlands. In doing so, the study identifies the strengths and possible weaknesses of the model in South Africa. The study discusses the extent to which the South African Twin Peaks model reflects international experience. The study traces the evolution of the financial markets and its regulation. It also delves into the main models of the regulation of financial services industry including the Twin Peaks model, which is the focus of the study. The rationale of South Africa’s adoption of the Twin Peaks model is also considered. The Twin Peaks model was introduced in South Africa through the enactment of the Financial Sector Regulatory Act. This legislation reveals that South Africa has drawn increasingly on international experience, particularly the structural design and the cooperation and collaboration of the regulators. It also reveals similarities, notable differences as well as characteristics that might be regarded as unique to South Africa. The similarities reveal that the South African Twin Peaks greatly aligns with that of its counterparts. This is exemplified through the cooperation and coordination between the regulators and the relationship between the regulators and the government amongst others. The study explores insights and lessons to South Africa which can be learnt from its counterparts like the need for effective coordination amongst the Twin Peak regulators. Thereafter, the study puts forward recommendations for reform, which can enable the effective implementation of the Twin Peaks financial regulatory architecture. , Thesis (MA) (Laws) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Marange, Patience https://orcid.org/ 0000-0003-4405-2702
- Date: 2021-09
- Subjects: Financial services industry , Financial services industry--Law and legislation
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/21278 , vital:48175
- Description: Over two decades ago, a number of countries have changed their financial regulatory models. The growing complexity of financial products, the increasing challenge of regulating large financial conglomerates, and the repercussions of the 2008 Global Financial Crisis, amongst other factors, have made regulatory reform a key priority for many economies. A move towards the Twin Peaks model of financial regulation has been one of the trends in recent years. This model sees regulation split into two broad functions which are market conduct regulation and prudential regulation. South Africa adopted the Twin Peaks financial regulatory model in 2017 as a way of strengthening its financial regulatory model. By adopting the Twin Peaks model, South Africa has become the eighth and the first developing country to adopt the financial regulatory model. The adoption of the Twin Peaks financial regulatory model in South Africa was mainly inspired by the effects of the 2008 Global Financial Crisis. This study undertakes a comparison of the Twin Peaks model structure in South Africa with the structure of its counterparts, which are Australia, United Kingdom and the Netherlands. In doing so, the study identifies the strengths and possible weaknesses of the model in South Africa. The study discusses the extent to which the South African Twin Peaks model reflects international experience. The study traces the evolution of the financial markets and its regulation. It also delves into the main models of the regulation of financial services industry including the Twin Peaks model, which is the focus of the study. The rationale of South Africa’s adoption of the Twin Peaks model is also considered. The Twin Peaks model was introduced in South Africa through the enactment of the Financial Sector Regulatory Act. This legislation reveals that South Africa has drawn increasingly on international experience, particularly the structural design and the cooperation and collaboration of the regulators. It also reveals similarities, notable differences as well as characteristics that might be regarded as unique to South Africa. The similarities reveal that the South African Twin Peaks greatly aligns with that of its counterparts. This is exemplified through the cooperation and coordination between the regulators and the relationship between the regulators and the government amongst others. The study explores insights and lessons to South Africa which can be learnt from its counterparts like the need for effective coordination amongst the Twin Peak regulators. Thereafter, the study puts forward recommendations for reform, which can enable the effective implementation of the Twin Peaks financial regulatory architecture. , Thesis (MA) (Laws) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09
An investigation on records management of student allocation for accommodation in selected universities of South Africa
- Authors: Mboya, Ncumisa
- Date: 2021-09
- Subjects: Records--Management
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23710 , vital:58584
- Description: The study aimed at investigating the management of students’ residential records at University of Fort Hare (UFH) and Rhodes University (RU). The objectives of the study were to: Investigate the residential policies and records management policies of the University of Fort Hare and Rhodes University; Assess the records management practices at the University of Fort Hare and Rhodes University; Determine how records management affects the process of allocating accommodation to students at the University of Fort Hare and Rhodes University; Identify areas of possible improvement of records management and student satisfaction concerning accommodation and allocation in both institutions. To achieve these objectives, the study used both qualitative and quantitative research methodologies. The data were collected using self-administered questionnaires and face-to-face interviews. A purposive non-probability sampling technique was used to select the participants of the study. Out of the targeted sample size of 39, the researcher administered questionnaires to 29 respondents and only 28 questionnaires were returned while 10 participants were interviewed. Therefore, a total of 38 staff members were included in the study. The qualitative data collected was analysed using thematic analysis while quantitative data collected was analysed using descriptive statistical analysis. The findings of the study showed that UFH and Rhodes University mostly make use of capturing process as one of the essential processes of records keeping used to allocate accommodation to students in their institutions. More importantly, the findings also revealed that there are different challenges faced by both universities. One of the challenges hindering student residence records at the University of Fort Hare (UFH) includes a lack of records xv management knowledge and incompetence. This might be because there are no records management personnel to take responsibility for student records. On the other hand, Rhodes University is faced with the unavailability of information sources, which might be attributed to a lack of information technology. , Thesis (MLIS) -- Faculty of Social Sciences and Humanities, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Mboya, Ncumisa
- Date: 2021-09
- Subjects: Records--Management
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23710 , vital:58584
- Description: The study aimed at investigating the management of students’ residential records at University of Fort Hare (UFH) and Rhodes University (RU). The objectives of the study were to: Investigate the residential policies and records management policies of the University of Fort Hare and Rhodes University; Assess the records management practices at the University of Fort Hare and Rhodes University; Determine how records management affects the process of allocating accommodation to students at the University of Fort Hare and Rhodes University; Identify areas of possible improvement of records management and student satisfaction concerning accommodation and allocation in both institutions. To achieve these objectives, the study used both qualitative and quantitative research methodologies. The data were collected using self-administered questionnaires and face-to-face interviews. A purposive non-probability sampling technique was used to select the participants of the study. Out of the targeted sample size of 39, the researcher administered questionnaires to 29 respondents and only 28 questionnaires were returned while 10 participants were interviewed. Therefore, a total of 38 staff members were included in the study. The qualitative data collected was analysed using thematic analysis while quantitative data collected was analysed using descriptive statistical analysis. The findings of the study showed that UFH and Rhodes University mostly make use of capturing process as one of the essential processes of records keeping used to allocate accommodation to students in their institutions. More importantly, the findings also revealed that there are different challenges faced by both universities. One of the challenges hindering student residence records at the University of Fort Hare (UFH) includes a lack of records xv management knowledge and incompetence. This might be because there are no records management personnel to take responsibility for student records. On the other hand, Rhodes University is faced with the unavailability of information sources, which might be attributed to a lack of information technology. , Thesis (MLIS) -- Faculty of Social Sciences and Humanities, 2021
- Full Text:
- Date Issued: 2021-09
Chemical composition and in vitro ruminal degradation of diets containing Vachellia karro leaf meal and their effect on physiological responses of indigenous Xhosa lop-eared goats
- Authors: Mfisi, Khanyisa
- Date: 2021-09
- Subjects: Ruminants--Feeding and feeds , Animal nutrition
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20719 , vital:46460
- Description: The objective of this study was to determine the chemical composition and in vitro ruminal dry matter degradation (DMD) of Vachellia karro leaf meal-containing diets and their effect on feed intake and physiological responses of indigenous Xhosa lop-eared goats. Experimental diets containing 0 percent (Treatment 1), 15 percent (Treatment 2) and 30 percent (Treatment 3) Vachellia karroo leaf meal were mixed with grass hay and crushed maize. Samples of each diet were analysed for chemical composition and in vitro ruminal DM degradability. A total of 18 eight-month-old indigenous Xhosa lop-eared goats, initially weighing 20.81 ± 1.83 kg were randomly assigned to each diet in a Completely Randomized Design. The goats were confined in individual well-ventilated roofed pens and each dietary treatment had a total of 6 goats. The feed was offered at a rate of 3 percent of live weight twice a day, at 08:00 in the morning and at 16:00 in the afternoon. The experimental feeding trial lasted for 80 days, where 10 days was allowed for adaptation. Goat live weight, Average daily feed intake (ADFI), and Body condition scores (BCS) were recorded weekly FAMACHA scores and fecal eggs counts were also determined weekly. Blood samples were collected via vein puncture on the last day of the feeding trial for determination of glucose, total cholesterol, albumin and blood urea. Significantly higher (P < 0.05) crude protein (CP) and condensed tannins (CT) levels were observed in Vachellia karroo containing diets., while acid detergent fibre (ADF) and neutral detergent fibre (NDF) were significantly higher (P < 0.05) in the control diet. During early hours of incubation, DMD was similar (P > 0.05) across all dietary treatments. At 12 to 72 hours, the DMD was significantly higher (P < 0.05) in Vachellia karroo containing diets except at 48 hours. Correlation between DMD and NDF, ADF and fat was only visible at 24 hours. Fibre (ADF and NDF) were negatively related to DMD, while fat was positively related. A positive correlation was observed between DMD and DM, CP and ADFI. The body weight and BCS of goats was similar (P > 0.05) in all dietary treatments (P > 0.05). The ADFI was significantly higher (P < 0.05) in Vachellia karroo supplemented goats. Faecal egg count and FAMACHA scores were significantly higher (P< 0.05) in the control group compared to the Vachellia karroo supplemented treatments; while glucose levels were significantly higher in goats supplemented with Vachellia karroo compared to non-supplemented goats. Cholesterol levels were similar (P > 0.05) across all experimental groups. Goats consuming 30 percent of Vachellia karroo leaf meal had higher (P < 0.05) creatinine levels than the non-supplemented treatment. Urea levels were significantly higher (P < 0.05) in goats fed 30 percent of Vachellia karroo leaf meal than other treatments. It was concluded that the inclusion of Vachellia karroo leaves improves diet quality, diet degradability, average daily feed intake and physiological responses. , Thesis (MSc) (Animal Science) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09
- Authors: Mfisi, Khanyisa
- Date: 2021-09
- Subjects: Ruminants--Feeding and feeds , Animal nutrition
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/20719 , vital:46460
- Description: The objective of this study was to determine the chemical composition and in vitro ruminal dry matter degradation (DMD) of Vachellia karro leaf meal-containing diets and their effect on feed intake and physiological responses of indigenous Xhosa lop-eared goats. Experimental diets containing 0 percent (Treatment 1), 15 percent (Treatment 2) and 30 percent (Treatment 3) Vachellia karroo leaf meal were mixed with grass hay and crushed maize. Samples of each diet were analysed for chemical composition and in vitro ruminal DM degradability. A total of 18 eight-month-old indigenous Xhosa lop-eared goats, initially weighing 20.81 ± 1.83 kg were randomly assigned to each diet in a Completely Randomized Design. The goats were confined in individual well-ventilated roofed pens and each dietary treatment had a total of 6 goats. The feed was offered at a rate of 3 percent of live weight twice a day, at 08:00 in the morning and at 16:00 in the afternoon. The experimental feeding trial lasted for 80 days, where 10 days was allowed for adaptation. Goat live weight, Average daily feed intake (ADFI), and Body condition scores (BCS) were recorded weekly FAMACHA scores and fecal eggs counts were also determined weekly. Blood samples were collected via vein puncture on the last day of the feeding trial for determination of glucose, total cholesterol, albumin and blood urea. Significantly higher (P < 0.05) crude protein (CP) and condensed tannins (CT) levels were observed in Vachellia karroo containing diets., while acid detergent fibre (ADF) and neutral detergent fibre (NDF) were significantly higher (P < 0.05) in the control diet. During early hours of incubation, DMD was similar (P > 0.05) across all dietary treatments. At 12 to 72 hours, the DMD was significantly higher (P < 0.05) in Vachellia karroo containing diets except at 48 hours. Correlation between DMD and NDF, ADF and fat was only visible at 24 hours. Fibre (ADF and NDF) were negatively related to DMD, while fat was positively related. A positive correlation was observed between DMD and DM, CP and ADFI. The body weight and BCS of goats was similar (P > 0.05) in all dietary treatments (P > 0.05). The ADFI was significantly higher (P < 0.05) in Vachellia karroo supplemented goats. Faecal egg count and FAMACHA scores were significantly higher (P< 0.05) in the control group compared to the Vachellia karroo supplemented treatments; while glucose levels were significantly higher in goats supplemented with Vachellia karroo compared to non-supplemented goats. Cholesterol levels were similar (P > 0.05) across all experimental groups. Goats consuming 30 percent of Vachellia karroo leaf meal had higher (P < 0.05) creatinine levels than the non-supplemented treatment. Urea levels were significantly higher (P < 0.05) in goats fed 30 percent of Vachellia karroo leaf meal than other treatments. It was concluded that the inclusion of Vachellia karroo leaves improves diet quality, diet degradability, average daily feed intake and physiological responses. , Thesis (MSc) (Animal Science) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-09