Incidence and molecular characterization of Hepatitis E virus from swine herds in the Eastern Cape province, South Africa
- Authors: Adelabu, Olusesan Adeyemi
- Date: 2016
- Subjects: Hepatitis -- South Africa -- Eastern Cape Virology -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/13966 , vital:39734
- Description: Hepatitis E virus-mediated infection is a serious public health concern in economically developing nations of the world. Globally, four major genotypes of HEV have been documented and the swine HEV identified to date in different countries belongs to either genotype 3 or 4. It has been reported to cross species barrier and cause infections in humans. Hence, Hepatitis E has been suggested to be zoonotic owing to the increase of evidence through various studies. Thus far, genotypes 1 and 2 are exclusively found in human population. However, little data are available regarding the occurrence of HEV in South Africa, especially in the Eastern Cape Province. Hence, this study was designed to assess the prevalence of Hepatitis E Virus among swine herd in selected communal and commercial farms in the Eastern Cape Province of South Africa. A total of 160 faecal samples were collected from swine herds in Amathole and Chris Hani District Municipalities of Eastern Cape Province and screened for the presence of HEV. Faecal samples were collected, using sterile swabs, from swine between the age of 2 to 6 months old, placed on ice and transported to the laboratory for further analysis. Viral RNA extraction was carried out followed by nested reverse-transcriptase polymerase chain reaction was used for amplification, after which the amplified products were examined by electrophoresis and viewed under ultraviolet illumination. The positive PCR products were sent for sequencing. Of the 160 faecal samples screened, only seven were positive (4.4percent) for HEV. The nucleotide sequence analyses revealed isolates UFT 01-03 sharing 82percent to 99percent identities with other strains with accession numbers KX896664, KX896665 and KX896666 and UMCF 01-04 with KX896667, KX896668, KX896669 and KX896670 from different regions of the world Phylogenetic analysis also showed that all seven isolates from this study clustered with both human and swine HEV from different geographical regions of the world especially with Japan Human and swine strains, Netherland swine HEV strains (AY032758, AF332620) and human HEV strain from France (JQ763611). We conclude that HEV is present among swine in the Eastern Cape Province, albeit in low incidence, and this does have public health implications. There is need for maintenance of high hygienic standards in order to prevent human infections through swine faecal materials and appropriate cooking of pork is highly advised.
- Full Text:
- Date Issued: 2016
- Authors: Adelabu, Olusesan Adeyemi
- Date: 2016
- Subjects: Hepatitis -- South Africa -- Eastern Cape Virology -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/13966 , vital:39734
- Description: Hepatitis E virus-mediated infection is a serious public health concern in economically developing nations of the world. Globally, four major genotypes of HEV have been documented and the swine HEV identified to date in different countries belongs to either genotype 3 or 4. It has been reported to cross species barrier and cause infections in humans. Hence, Hepatitis E has been suggested to be zoonotic owing to the increase of evidence through various studies. Thus far, genotypes 1 and 2 are exclusively found in human population. However, little data are available regarding the occurrence of HEV in South Africa, especially in the Eastern Cape Province. Hence, this study was designed to assess the prevalence of Hepatitis E Virus among swine herd in selected communal and commercial farms in the Eastern Cape Province of South Africa. A total of 160 faecal samples were collected from swine herds in Amathole and Chris Hani District Municipalities of Eastern Cape Province and screened for the presence of HEV. Faecal samples were collected, using sterile swabs, from swine between the age of 2 to 6 months old, placed on ice and transported to the laboratory for further analysis. Viral RNA extraction was carried out followed by nested reverse-transcriptase polymerase chain reaction was used for amplification, after which the amplified products were examined by electrophoresis and viewed under ultraviolet illumination. The positive PCR products were sent for sequencing. Of the 160 faecal samples screened, only seven were positive (4.4percent) for HEV. The nucleotide sequence analyses revealed isolates UFT 01-03 sharing 82percent to 99percent identities with other strains with accession numbers KX896664, KX896665 and KX896666 and UMCF 01-04 with KX896667, KX896668, KX896669 and KX896670 from different regions of the world Phylogenetic analysis also showed that all seven isolates from this study clustered with both human and swine HEV from different geographical regions of the world especially with Japan Human and swine strains, Netherland swine HEV strains (AY032758, AF332620) and human HEV strain from France (JQ763611). We conclude that HEV is present among swine in the Eastern Cape Province, albeit in low incidence, and this does have public health implications. There is need for maintenance of high hygienic standards in order to prevent human infections through swine faecal materials and appropriate cooking of pork is highly advised.
- Full Text:
- Date Issued: 2016
A qualitative assessment of the achievement of gender equality under education for all (EFA) goals : study of Lagos State, Nigeria
- Authors: Adeleke, Adawi Adeola
- Date: 2018
- Subjects: Sex discrimination in education -- Nigeria Sexism in education -- Nigeria Educational equalization -- Nigeria
- Language: English
- Type: Thesis , Doctoral , Education
- Identifier: http://hdl.handle.net/10353/9500 , vital:34357
- Description: The importance of education cannot be overemphasized. Education has been identified as the most critical instrument for empowering individuals with the necessary knowledge and skills, which can give them access to productive employment. Also, the future of a country is based on the quality of education acquired by its citizens which helps in transforming it from pre-literate to contemporary nationhood. Many international treaties and initiatives in the world have made special provisions for education as a duty of every government which must be given to every citizen as of right, irrespective of gender or social class. Amongst these international initiatives is the Education for All (EFA) Goals, a time-bound global movement towards the provision of education for every one led by the United Nations Educational, Scientific and Cultural Organization (UNESCO). There are six goals in all. This study investigated one of the EFA goals, the goal 5. The aim of the study was a qualitative assessment of the achievement of gender equality goal under the Education for All (EFA) goals, a study of Lagos State, Nigeria. The theoretical framework of the study is informed by the Social Justice Theory and the Social Justice Praxis Theory. Scholarly works and literatures on girl-child education, gender and education, and gender balancing in education were reviewed. The study followed qualitative research approach which utilizes an interpretive research paradigm that provides a collective voice from the participants. The research area was purposively selected as Lagos State being a former capital of Nigeria and still the commercial nerve centre of the nation. Although it is the smallest state in Nigeria in term of size, it remains the most populous in the country with a projected population of 20,546,999 (13.5percent Nigeria’s total population). A sample of 16 participants were purposively selected because they were the officers directly in charge of the implementation government policies on education in the State. The data was collected through in-depth recorded interview sessions and secondary data were sourced through official documents downloaded online and from Lagos State Ministry of Education. Based on the thematic analysis of the data collected, the study found out that the State government had established policies and measures to provide qualitative education for all the citizens on a non-discriminatory basis. Thus, the goal of gender parity in terms of enrollment of boys and girls has been relatively achieved in the state. However, there were still some challenges of equality in the learning process and outcome. The study therefore recommends that schools should be made attractive and conducive as possible to assist the educational attainment of any student. This could be achieved by promoting positive values and attitudes towards education, all the stakeholders in the education sector must be involved in the business of running the school. There should also be a form of resourcing and expansion of the school facilities through the Public - Private Partnership in education.
- Full Text:
- Date Issued: 2018
- Authors: Adeleke, Adawi Adeola
- Date: 2018
- Subjects: Sex discrimination in education -- Nigeria Sexism in education -- Nigeria Educational equalization -- Nigeria
- Language: English
- Type: Thesis , Doctoral , Education
- Identifier: http://hdl.handle.net/10353/9500 , vital:34357
- Description: The importance of education cannot be overemphasized. Education has been identified as the most critical instrument for empowering individuals with the necessary knowledge and skills, which can give them access to productive employment. Also, the future of a country is based on the quality of education acquired by its citizens which helps in transforming it from pre-literate to contemporary nationhood. Many international treaties and initiatives in the world have made special provisions for education as a duty of every government which must be given to every citizen as of right, irrespective of gender or social class. Amongst these international initiatives is the Education for All (EFA) Goals, a time-bound global movement towards the provision of education for every one led by the United Nations Educational, Scientific and Cultural Organization (UNESCO). There are six goals in all. This study investigated one of the EFA goals, the goal 5. The aim of the study was a qualitative assessment of the achievement of gender equality goal under the Education for All (EFA) goals, a study of Lagos State, Nigeria. The theoretical framework of the study is informed by the Social Justice Theory and the Social Justice Praxis Theory. Scholarly works and literatures on girl-child education, gender and education, and gender balancing in education were reviewed. The study followed qualitative research approach which utilizes an interpretive research paradigm that provides a collective voice from the participants. The research area was purposively selected as Lagos State being a former capital of Nigeria and still the commercial nerve centre of the nation. Although it is the smallest state in Nigeria in term of size, it remains the most populous in the country with a projected population of 20,546,999 (13.5percent Nigeria’s total population). A sample of 16 participants were purposively selected because they were the officers directly in charge of the implementation government policies on education in the State. The data was collected through in-depth recorded interview sessions and secondary data were sourced through official documents downloaded online and from Lagos State Ministry of Education. Based on the thematic analysis of the data collected, the study found out that the State government had established policies and measures to provide qualitative education for all the citizens on a non-discriminatory basis. Thus, the goal of gender parity in terms of enrollment of boys and girls has been relatively achieved in the state. However, there were still some challenges of equality in the learning process and outcome. The study therefore recommends that schools should be made attractive and conducive as possible to assist the educational attainment of any student. This could be achieved by promoting positive values and attitudes towards education, all the stakeholders in the education sector must be involved in the business of running the school. There should also be a form of resourcing and expansion of the school facilities through the Public - Private Partnership in education.
- Full Text:
- Date Issued: 2018
Ultraprecision Diamond Turning of Monocrystalline Germanium
- Authors: Adeleke, Adeniyi Kehinde
- Date: 2021-04
- Subjects: Precision , Diamond Turning
- Language: English
- Type: Master's theses , Thesis
- Identifier: http://hdl.handle.net/10948/44453 , vital:37835
- Description: Infrared lens production demands a surface with a high degree of accuracy and integrity. Surface roughness is a critical index of the measure of any product’s surface integrity. As a result of this, ultra-high machining technology has enjoyed extensive application, due to the continuous request for components within the range of 1 – 10nm roughness value. This technology has brought about the increased productivity and manufacture of quality products with a top-notch surface finish. Brittle materials such as germanium are hard to machine through the conventional processes such as lapping and polishing. Hence, the ultra-precision machining technology based on single point diamond turning (SPDT), is now been applied to machine germanium in the ductile mode, where material chip removal occurs by plastic deformation instead of a brittle fracture. During machining, selecting the optimal cutting conditions which includes cutting parameters and tool geometry, will not only improve productivity but ensure the minimisation of operating cost. In this research work, SPDT operation was used to conduct two experiments on a (monocrystalline germanium) workpiece. The first experiment was carried out using a diamond tool with a 1.5 mm nose radius, while the second experiment employed the use of a tool having a nose radius of 1.0 mm. A combination of machining parameters for each of the experimental runs were derived from a Box-Behnken method of design and the surface roughness was measured at each interval for both experiments with the aid of a Taylor Hopson PGI Dimension XL profilometer. Acoustic emission (AE) was also used as a quality sensing and tool-monitoring technique, to acquire signals and give indications of the expected surface roughness. Predictive models based on response surface methodology (RSM) and artificial neural networks (ANN), were developed for determining surface roughness. Optimisation was performed using RSM to determine the optimal set of machining factors, which results in optimal condition of the output response. Further investigations on the acquired signals were carried out using signal-processing techniques. Time-domain and time-frequency domain features acquired from the AE signals, together with the process parameters, were employed as input variables in the neural network design, having shown a good association with the surface roughness. ix Conclusively, it can be observed that the predictive model results and the experimental roughness measurements are in good agreement with each other. For accuracy and cost of computation, the RSM and ANN developed models for single-crystal germanium are compared using mean absolute error (MAE). , Thesis (M.Eng) -- Faculty of Engineering, the built environment & Information Technology, 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Adeleke, Adeniyi Kehinde
- Date: 2021-04
- Subjects: Precision , Diamond Turning
- Language: English
- Type: Master's theses , Thesis
- Identifier: http://hdl.handle.net/10948/44453 , vital:37835
- Description: Infrared lens production demands a surface with a high degree of accuracy and integrity. Surface roughness is a critical index of the measure of any product’s surface integrity. As a result of this, ultra-high machining technology has enjoyed extensive application, due to the continuous request for components within the range of 1 – 10nm roughness value. This technology has brought about the increased productivity and manufacture of quality products with a top-notch surface finish. Brittle materials such as germanium are hard to machine through the conventional processes such as lapping and polishing. Hence, the ultra-precision machining technology based on single point diamond turning (SPDT), is now been applied to machine germanium in the ductile mode, where material chip removal occurs by plastic deformation instead of a brittle fracture. During machining, selecting the optimal cutting conditions which includes cutting parameters and tool geometry, will not only improve productivity but ensure the minimisation of operating cost. In this research work, SPDT operation was used to conduct two experiments on a (monocrystalline germanium) workpiece. The first experiment was carried out using a diamond tool with a 1.5 mm nose radius, while the second experiment employed the use of a tool having a nose radius of 1.0 mm. A combination of machining parameters for each of the experimental runs were derived from a Box-Behnken method of design and the surface roughness was measured at each interval for both experiments with the aid of a Taylor Hopson PGI Dimension XL profilometer. Acoustic emission (AE) was also used as a quality sensing and tool-monitoring technique, to acquire signals and give indications of the expected surface roughness. Predictive models based on response surface methodology (RSM) and artificial neural networks (ANN), were developed for determining surface roughness. Optimisation was performed using RSM to determine the optimal set of machining factors, which results in optimal condition of the output response. Further investigations on the acquired signals were carried out using signal-processing techniques. Time-domain and time-frequency domain features acquired from the AE signals, together with the process parameters, were employed as input variables in the neural network design, having shown a good association with the surface roughness. ix Conclusively, it can be observed that the predictive model results and the experimental roughness measurements are in good agreement with each other. For accuracy and cost of computation, the RSM and ANN developed models for single-crystal germanium are compared using mean absolute error (MAE). , Thesis (M.Eng) -- Faculty of Engineering, the built environment & Information Technology, 2021
- Full Text:
- Date Issued: 2021-04
Isolation, propagation and rapid molecular detection of the Kalahari truffle, a mycorrhizal fungus occurring in South Africa
- Authors: Adeleke, Rasheed Adegbola
- Date: 2007 , 2013-04-03
- Subjects: Truffles -- Kalahari Desert , Fungi -- Identification , Mycorrhizal fungi -- South Africa , Edible fungi -- South Africa , Mushroom culture -- South Africa , Fungi -- Cultures and culture media -- South Africa , Truffles -- South Africa , Truffles -- Lifecycles , Mycorrhizal fungi -- Lifecycles
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3889 , http://hdl.handle.net/10962/d1002951 , Truffles -- Kalahari Desert , Fungi -- Identification , Mycorrhizal fungi -- South Africa , Edible fungi -- South Africa , Mushroom culture -- South Africa , Fungi -- Cultures and culture media -- South Africa , Truffles -- South Africa , Truffles -- Lifecycles , Mycorrhizal fungi -- Lifecycles
- Description: Terfezia pfeilii is an edible mycorrhizal fungus that thrives in the Kalahari Desert of southern Africa. It is best known by desert dwellers for its flavour and as a source of nutrition. Although the genus Terfezia is generally regarded as being an ectomycorrhizal mycobiont, the exact mycorrhizal type formed by T. pfeilli and its' associated host plants remains uncertain. Discovery of the host plants for T. pfeilii would first be required in order to further investigate the life cycle and cultivation of this truffle. This study focussed on the isolation of mycelia from the ascocarp, optimising the growth conditions of the mycelial cultures, rapid molecular identification of T. pfeilii, investigation of potential helper bacteria and mycorrhizal synthesis experiments. T. pfeilii ascocarps were harvested from the Spitskop Nature Reserve in Upington, South Africa. Ascocarps were successfully identified using both morphological and molecular methods. Despite the delayed growth mostly caused by contaminating microorganisms, the isolation of T. pfeilii mycelia culture was successful. Molecular techniques were used to confirm the identity of the pure culture. Further studies were conducted on ways to improve the growth conditions of the mycelial culture on Fontana medium. An optimum temperature of 32°C, the addition of Bovine Serum Albumin as a nitrogen source and a pH of 7.5 significantly improved the growth of T. pfeilii in vitro. A rapid PeR-based molecular method was developed to speed up the identification of T. pfeilii. Specific primers that can exclusively amplify the ITS region of T. pfeilii were designed and used to identify both the ascocarps and the mycelial culture. The specificity of these primers was confirmed by their inability to amplify DNA from the isolates of contamining fungi obtained during the isolation process. Molecular comparison was made to confirm the reclassification of South African samples of T. pfeilii as Kalaharituber pfeilii as proposed by Ferdman et al.,(2005). However, in this study, the name T. pfeilii has been retained. A total of 17 bacterial isolates were obtained from the fruiting bodies of T. pfeaii and these were tested for stimulation of mycelial growth in vitro, indole production and phosphate solubilising capabilities. Bacterial isolates that showed potential to be Mycorrhization Helper Bacteria (MHB) were identified as Paenibacillus sp., Bacillus sp. and Rhizobium tropici. Selected plant seedlings were inoculated with T. pfeilii cultures or ascocarp slurry in order to re-establish the mycorrhizal association. After 8 months, light microscopy observations revealed an endomycorrhizal type association between Cynodon dactylon and T. pfeilii. This was confirmed with molecular analysis using specific T. pfeilii ITS primers. After 15 months, molecular methods confirmed Acacia erioloba as another host plant. These results have provided essential information paving the way for further investigation into the life cycle and biology of the Kalahari truffle. , KMBT_363 , Adobe Acrobat 9.53 Paper Capture Plug-in
- Full Text:
- Date Issued: 2007
- Authors: Adeleke, Rasheed Adegbola
- Date: 2007 , 2013-04-03
- Subjects: Truffles -- Kalahari Desert , Fungi -- Identification , Mycorrhizal fungi -- South Africa , Edible fungi -- South Africa , Mushroom culture -- South Africa , Fungi -- Cultures and culture media -- South Africa , Truffles -- South Africa , Truffles -- Lifecycles , Mycorrhizal fungi -- Lifecycles
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3889 , http://hdl.handle.net/10962/d1002951 , Truffles -- Kalahari Desert , Fungi -- Identification , Mycorrhizal fungi -- South Africa , Edible fungi -- South Africa , Mushroom culture -- South Africa , Fungi -- Cultures and culture media -- South Africa , Truffles -- South Africa , Truffles -- Lifecycles , Mycorrhizal fungi -- Lifecycles
- Description: Terfezia pfeilii is an edible mycorrhizal fungus that thrives in the Kalahari Desert of southern Africa. It is best known by desert dwellers for its flavour and as a source of nutrition. Although the genus Terfezia is generally regarded as being an ectomycorrhizal mycobiont, the exact mycorrhizal type formed by T. pfeilli and its' associated host plants remains uncertain. Discovery of the host plants for T. pfeilii would first be required in order to further investigate the life cycle and cultivation of this truffle. This study focussed on the isolation of mycelia from the ascocarp, optimising the growth conditions of the mycelial cultures, rapid molecular identification of T. pfeilii, investigation of potential helper bacteria and mycorrhizal synthesis experiments. T. pfeilii ascocarps were harvested from the Spitskop Nature Reserve in Upington, South Africa. Ascocarps were successfully identified using both morphological and molecular methods. Despite the delayed growth mostly caused by contaminating microorganisms, the isolation of T. pfeilii mycelia culture was successful. Molecular techniques were used to confirm the identity of the pure culture. Further studies were conducted on ways to improve the growth conditions of the mycelial culture on Fontana medium. An optimum temperature of 32°C, the addition of Bovine Serum Albumin as a nitrogen source and a pH of 7.5 significantly improved the growth of T. pfeilii in vitro. A rapid PeR-based molecular method was developed to speed up the identification of T. pfeilii. Specific primers that can exclusively amplify the ITS region of T. pfeilii were designed and used to identify both the ascocarps and the mycelial culture. The specificity of these primers was confirmed by their inability to amplify DNA from the isolates of contamining fungi obtained during the isolation process. Molecular comparison was made to confirm the reclassification of South African samples of T. pfeilii as Kalaharituber pfeilii as proposed by Ferdman et al.,(2005). However, in this study, the name T. pfeilii has been retained. A total of 17 bacterial isolates were obtained from the fruiting bodies of T. pfeaii and these were tested for stimulation of mycelial growth in vitro, indole production and phosphate solubilising capabilities. Bacterial isolates that showed potential to be Mycorrhization Helper Bacteria (MHB) were identified as Paenibacillus sp., Bacillus sp. and Rhizobium tropici. Selected plant seedlings were inoculated with T. pfeilii cultures or ascocarp slurry in order to re-establish the mycorrhizal association. After 8 months, light microscopy observations revealed an endomycorrhizal type association between Cynodon dactylon and T. pfeilii. This was confirmed with molecular analysis using specific T. pfeilii ITS primers. After 15 months, molecular methods confirmed Acacia erioloba as another host plant. These results have provided essential information paving the way for further investigation into the life cycle and biology of the Kalahari truffle. , KMBT_363 , Adobe Acrobat 9.53 Paper Capture Plug-in
- Full Text:
- Date Issued: 2007
Evaluation of some pharmaceutical and personal care products and pesticide residues in selected wastewater treatment plants and receiving watersheds in Eastern Cape, South Africa
- Ademoyegun, Olufemi Temitope
- Authors: Ademoyegun, Olufemi Temitope
- Date: 2017
- Subjects: Emerging contaminants in water -- South Africa -- Eastern Cape Water treatment plants -- Waste disposal -- South Africa -- Eastern Cape Organic compounds -- Environmental aspects -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/2922 , vital:28138
- Description: Emerging organic contaminants (EOCs) have been the focus of global environmental research for over three decades. EOCs have caused widespread concern due to their extensive use. As EOCs were designed to correct, enhance or protect a specific physiological, their target effects in humans and/or farm stocks are relatively well known and documented. However, there is limited knowledge about their unintended effects in the environment. To address the occurrence, distribution and fate of EOCs in the environment, efficient and reliable analytical methods are needed. The relatively low concentration, high polarity, and thermal lability of some EOCs, together with their interaction with complex environmental matrices, make their analysis challenging. Sample preparation followed by GC or HPLC separation and mass spectrometry (MS) detection has become the standard approach for evaluating EOCs in environmental samples. Physicochemical properties of EOCs range from highly water-soluble (hydrophylic) to highly water-insoluble (hydrophobic). Two groups of these EOCs were considered for study in this work. Pharmaceutical and personal care products (PPCPs) were comprehensively studied in five wastewater treatment plants and their receiving watersheds in Amathole districts in Eastern C ape, South Africa. PPCPs have been widely reported in wastewater influents, effluents, receiving rivers and biosolids, but reports of their occurrence in all these matrixes have been limited by the difficulty of analysis. Therefore, a comprehensive validation of methods was carried out on the influents, effluents, sludge and soil from the irrigated golf course where the effluent of one of the study sites was being used for over three decades now for irrigation. In all, thirteen PPCPs from five therapeutic groups were selected for study in this work because of their administering rate and availability of analytical instrument. Good limit of detection (LOD) and limit of quantification (LOQ) were achieved for the method used. The LOD for the aqueous Three different technologies were employed for the treatment of wastewater in the five selected wastewater treatment plants (WWTPs) and study was carried out to evaluate their ability to eliminate the selected compounds from the influents to the effluents using statistical analysis (ANOVA) at p<0.05 on the percentage removal rate across the three plants. The results had shown eight of the compounds having no significant difference among the treatment operations, whereas the remaining five compounds varied significantly among the treatment technologies under investigation. Principal component analysis was performed on the concentration of PPCPs, their removal rate and also on the physicochemical and treatment operation parameters. Hydraulic retention time (HRT) had correlation coefficient, r = 0.90 with the concentration of PPCPs and removal rates. Furthermore, occurrences, seasonal variation, mean concentration distribution pattern of the compounds, and temporal evaluation of the mean concentration of the pharmaceutical compounds in the five WWTPs during one year of sampling were considered. The results revealed that five products which were diclofenac, ibuprofen, paracetamol, triclosan and diethyl toluamide (DDET) were predominant among the PPCPs in all the WWTPs. The removal efficiency was highest in caffeine with 96 percent, and the lowest was obtained with carbamazepine (4 percent). Risk quotient of the concentration of PPCPs in the effluents and receiving waters was determined to assess their chronic toxicity at three trophic levels: fish, algae and matrixes studied ranged from 0.01 μg/L to 0.25 μg/L, and the LOQ from 0.02 μg/L to 0.78 μg/L. In the solid matrixes, LOD varied from 0.01 ng/g to 0.65 ng/g, and the LOQ between 0.08 ng/g and 5.17 ng/g. Better recovery efficiency was obtained with this mixture of solvents, acetone: dichloromethane (1:1), for the recovery of the five therapeutic groups in the solid matrixes using ultrasonication- assisted techniques. The results show percentage recovery values ranging from 68.8 percent to 107.5 percent diaphian. According to the environmental risk assessment results, ibuprofen and triclosan were found to be the most critical compounds due to their high risk quotient values. These findings will, therefore, help in the future evaluation of the efficiency of different treatment technologies in the removal of various PPCPs from the wastewater and their sustainable management in the aquatic resources in Eastern Cape, South Africa. For the lipophilic organochlorine pesticides (OCPs), the limits of detection (LODs) of the tested congeners varied from 0.04 ng/g (α-BHC) to 0.49 ng/g (endosulfan sulfate) and the limits of quantification ranging from 0.22 ng/g (aldrin) to 2.17 ng/g (δ-BHC).
- Full Text:
- Date Issued: 2017
- Authors: Ademoyegun, Olufemi Temitope
- Date: 2017
- Subjects: Emerging contaminants in water -- South Africa -- Eastern Cape Water treatment plants -- Waste disposal -- South Africa -- Eastern Cape Organic compounds -- Environmental aspects -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/2922 , vital:28138
- Description: Emerging organic contaminants (EOCs) have been the focus of global environmental research for over three decades. EOCs have caused widespread concern due to their extensive use. As EOCs were designed to correct, enhance or protect a specific physiological, their target effects in humans and/or farm stocks are relatively well known and documented. However, there is limited knowledge about their unintended effects in the environment. To address the occurrence, distribution and fate of EOCs in the environment, efficient and reliable analytical methods are needed. The relatively low concentration, high polarity, and thermal lability of some EOCs, together with their interaction with complex environmental matrices, make their analysis challenging. Sample preparation followed by GC or HPLC separation and mass spectrometry (MS) detection has become the standard approach for evaluating EOCs in environmental samples. Physicochemical properties of EOCs range from highly water-soluble (hydrophylic) to highly water-insoluble (hydrophobic). Two groups of these EOCs were considered for study in this work. Pharmaceutical and personal care products (PPCPs) were comprehensively studied in five wastewater treatment plants and their receiving watersheds in Amathole districts in Eastern C ape, South Africa. PPCPs have been widely reported in wastewater influents, effluents, receiving rivers and biosolids, but reports of their occurrence in all these matrixes have been limited by the difficulty of analysis. Therefore, a comprehensive validation of methods was carried out on the influents, effluents, sludge and soil from the irrigated golf course where the effluent of one of the study sites was being used for over three decades now for irrigation. In all, thirteen PPCPs from five therapeutic groups were selected for study in this work because of their administering rate and availability of analytical instrument. Good limit of detection (LOD) and limit of quantification (LOQ) were achieved for the method used. The LOD for the aqueous Three different technologies were employed for the treatment of wastewater in the five selected wastewater treatment plants (WWTPs) and study was carried out to evaluate their ability to eliminate the selected compounds from the influents to the effluents using statistical analysis (ANOVA) at p<0.05 on the percentage removal rate across the three plants. The results had shown eight of the compounds having no significant difference among the treatment operations, whereas the remaining five compounds varied significantly among the treatment technologies under investigation. Principal component analysis was performed on the concentration of PPCPs, their removal rate and also on the physicochemical and treatment operation parameters. Hydraulic retention time (HRT) had correlation coefficient, r = 0.90 with the concentration of PPCPs and removal rates. Furthermore, occurrences, seasonal variation, mean concentration distribution pattern of the compounds, and temporal evaluation of the mean concentration of the pharmaceutical compounds in the five WWTPs during one year of sampling were considered. The results revealed that five products which were diclofenac, ibuprofen, paracetamol, triclosan and diethyl toluamide (DDET) were predominant among the PPCPs in all the WWTPs. The removal efficiency was highest in caffeine with 96 percent, and the lowest was obtained with carbamazepine (4 percent). Risk quotient of the concentration of PPCPs in the effluents and receiving waters was determined to assess their chronic toxicity at three trophic levels: fish, algae and matrixes studied ranged from 0.01 μg/L to 0.25 μg/L, and the LOQ from 0.02 μg/L to 0.78 μg/L. In the solid matrixes, LOD varied from 0.01 ng/g to 0.65 ng/g, and the LOQ between 0.08 ng/g and 5.17 ng/g. Better recovery efficiency was obtained with this mixture of solvents, acetone: dichloromethane (1:1), for the recovery of the five therapeutic groups in the solid matrixes using ultrasonication- assisted techniques. The results show percentage recovery values ranging from 68.8 percent to 107.5 percent diaphian. According to the environmental risk assessment results, ibuprofen and triclosan were found to be the most critical compounds due to their high risk quotient values. These findings will, therefore, help in the future evaluation of the efficiency of different treatment technologies in the removal of various PPCPs from the wastewater and their sustainable management in the aquatic resources in Eastern Cape, South Africa. For the lipophilic organochlorine pesticides (OCPs), the limits of detection (LODs) of the tested congeners varied from 0.04 ng/g (α-BHC) to 0.49 ng/g (endosulfan sulfate) and the limits of quantification ranging from 0.22 ng/g (aldrin) to 2.17 ng/g (δ-BHC).
- Full Text:
- Date Issued: 2017
An entrepreneurial framework for deciding on the implementation of large format digital printing internationally
- Adendorff, Christian Michael
- Authors: Adendorff, Christian Michael
- Date: 2003
- Subjects: Entrepreneurship , Success in business , Business -- Technological innovations , Digital printing
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1169 , http://hdl.handle.net/10962/d1002785 , Entrepreneurship , Success in business , Business -- Technological innovations , Digital printing
- Description: This study focuses on entrepreneurs within the SME sector using large format digital printing (LFDP) because of the changes in technology that influences the decisionmaking processes of the entrepreneur in the purchasing of a new LFDP. These fast changes are likely to continue and can cause technologies to become obsolete overnight. The entrepreneurs within the LFDP industry find themselves in the midst of these fast changes and are faced with a dilemma. On the one hand, they need to make sure that the technology used produces consistent and quality products. On the other hand, the entrepreneur needs to ensure an optimal return on investments. From the literature and the findings of the study, the researcher recommends a change to an existing model on a consultant involvement purchase of high technology products, which is then adapted to integrate resource-forecasting areas together with timing and type of information required as well as external environment scanning. The existing model’s focus is on the individual’s ability to make decisions based on their own knowledge. However, by integrating technology forecasting components, and scanning the business environment and resource forecasting needed the decision-maker will be better equipped to make decisions that also takes into account the external environment. This will also allow them to plan and manage growth in a systematic way. Therefore the proposed model takes into account individual capabilities and technology forecasting components that can facilitate the decision-making process. The adapted model on decision-making clearly delineates that the combination of entrepreneurial qualities and technology forecasting techniques in the LFDP industry will ultimately assist the entrepreneur on various levels in deciding on a new LFDP.
- Full Text:
- Date Issued: 2003
- Authors: Adendorff, Christian Michael
- Date: 2003
- Subjects: Entrepreneurship , Success in business , Business -- Technological innovations , Digital printing
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1169 , http://hdl.handle.net/10962/d1002785 , Entrepreneurship , Success in business , Business -- Technological innovations , Digital printing
- Description: This study focuses on entrepreneurs within the SME sector using large format digital printing (LFDP) because of the changes in technology that influences the decisionmaking processes of the entrepreneur in the purchasing of a new LFDP. These fast changes are likely to continue and can cause technologies to become obsolete overnight. The entrepreneurs within the LFDP industry find themselves in the midst of these fast changes and are faced with a dilemma. On the one hand, they need to make sure that the technology used produces consistent and quality products. On the other hand, the entrepreneur needs to ensure an optimal return on investments. From the literature and the findings of the study, the researcher recommends a change to an existing model on a consultant involvement purchase of high technology products, which is then adapted to integrate resource-forecasting areas together with timing and type of information required as well as external environment scanning. The existing model’s focus is on the individual’s ability to make decisions based on their own knowledge. However, by integrating technology forecasting components, and scanning the business environment and resource forecasting needed the decision-maker will be better equipped to make decisions that also takes into account the external environment. This will also allow them to plan and manage growth in a systematic way. Therefore the proposed model takes into account individual capabilities and technology forecasting components that can facilitate the decision-making process. The adapted model on decision-making clearly delineates that the combination of entrepreneurial qualities and technology forecasting techniques in the LFDP industry will ultimately assist the entrepreneur on various levels in deciding on a new LFDP.
- Full Text:
- Date Issued: 2003
Possible futures for the Republic of South Africa towards 2055
- Adendorff, Christian Michael
- Authors: Adendorff, Christian Michael
- Date: 2013
- Subjects: Economic development -- South Africa , Sustainable development -- South Africa
- Language: English
- Type: Thesis , Doctoral , DBA
- Identifier: http://hdl.handle.net/10948/7816 , vital:24294
- Description: The purpose of this thesis was to develop four scenarios for South Africa over the next forty years: Mandela's Dream in which positive elements come into function for South Africa's economy and governance; the Historical African Syndrome, in which the key driving forces unfold in an uneven pattern, or have a differentiated impact on South Africa's economy; the Good, the Bad and the Ugly in which less good governance prevails, but where a fortunate economy and firm national management allow South Africa to become competitive and benefit from satisfactory economic growth; and the Pyramid Syndrome Scenario in which negative regional drivers of change corrode positive policies and initiatives in a manner which compounds the pre-existing threats to South Africa's growth.
- Full Text:
- Date Issued: 2013
- Authors: Adendorff, Christian Michael
- Date: 2013
- Subjects: Economic development -- South Africa , Sustainable development -- South Africa
- Language: English
- Type: Thesis , Doctoral , DBA
- Identifier: http://hdl.handle.net/10948/7816 , vital:24294
- Description: The purpose of this thesis was to develop four scenarios for South Africa over the next forty years: Mandela's Dream in which positive elements come into function for South Africa's economy and governance; the Historical African Syndrome, in which the key driving forces unfold in an uneven pattern, or have a differentiated impact on South Africa's economy; the Good, the Bad and the Ugly in which less good governance prevails, but where a fortunate economy and firm national management allow South Africa to become competitive and benefit from satisfactory economic growth; and the Pyramid Syndrome Scenario in which negative regional drivers of change corrode positive policies and initiatives in a manner which compounds the pre-existing threats to South Africa's growth.
- Full Text:
- Date Issued: 2013
The development of a cultural family business model of good governance for Greek family businesses in South Africa
- Adendorff, Christian Michael
- Authors: Adendorff, Christian Michael
- Date: 2005
- Subjects: Family-owned business enterprises -- South Africa Greeks -- South Africa Greeks -- South Africa -- Social life and customs Corporate governance -- South Africa South Africa -- Economic conditions
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:1163 , http://hdl.handle.net/10962/d1002779
- Description: Never in the history of the South African nation has the entrepreneurial spirit been more alive. Since the opening of international doors, after the 1994 elections, South Africa has experienced the explosive growth of transnational entrepreneurship. An enduring aspect of the explosion of such economic activity is the need for "good governance" and the need for governance education in South Africa and the rest of the continent has never been greater. The size of the family business component of the South Aftican economy suggests that it is the predominant way of doing business in South Africa. Of importance to this study is the estimate that approximately 95 % of all Greek businesses in South Africa can be classified as family businesses. The sustainability of Greek family businesses requires that they maintain good governance practices that are economically and environmentally acceptable to all stakeholders. It also requires that the next generation of Greek entrepreneurs balance good governance for the businesses as well as for the family. The primary objective of this study was to identify and explore the internal factors that influence and determine good governance to ensure the survival, growth and sustainability of Greek family businesses in South Africa. The secondary research objectives pertained to the underlying dimensions of good governance and required an exploration of the different governance concerns in relation to specific South African Greek behaviour and characteristics. A theoretical model of good governance factors was proposed and tested using Structural Equation Modeling. The study found that perceived good governance in a South African Greek family business context needs to be measured in terms of three factors, namely risk control, the internal regulatory environment and the protection of the stakeholders' interest. The study dealt further with the secondary sources effecting governance for South African businesses and was based on the latest report by the King Commission. An important finding is that the cross cultural aspect of family business governance must now be considered when conducting such research as more and more emphasis is placed on the good governance of all businesses.
- Full Text:
- Date Issued: 2005
- Authors: Adendorff, Christian Michael
- Date: 2005
- Subjects: Family-owned business enterprises -- South Africa Greeks -- South Africa Greeks -- South Africa -- Social life and customs Corporate governance -- South Africa South Africa -- Economic conditions
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:1163 , http://hdl.handle.net/10962/d1002779
- Description: Never in the history of the South African nation has the entrepreneurial spirit been more alive. Since the opening of international doors, after the 1994 elections, South Africa has experienced the explosive growth of transnational entrepreneurship. An enduring aspect of the explosion of such economic activity is the need for "good governance" and the need for governance education in South Africa and the rest of the continent has never been greater. The size of the family business component of the South Aftican economy suggests that it is the predominant way of doing business in South Africa. Of importance to this study is the estimate that approximately 95 % of all Greek businesses in South Africa can be classified as family businesses. The sustainability of Greek family businesses requires that they maintain good governance practices that are economically and environmentally acceptable to all stakeholders. It also requires that the next generation of Greek entrepreneurs balance good governance for the businesses as well as for the family. The primary objective of this study was to identify and explore the internal factors that influence and determine good governance to ensure the survival, growth and sustainability of Greek family businesses in South Africa. The secondary research objectives pertained to the underlying dimensions of good governance and required an exploration of the different governance concerns in relation to specific South African Greek behaviour and characteristics. A theoretical model of good governance factors was proposed and tested using Structural Equation Modeling. The study found that perceived good governance in a South African Greek family business context needs to be measured in terms of three factors, namely risk control, the internal regulatory environment and the protection of the stakeholders' interest. The study dealt further with the secondary sources effecting governance for South African businesses and was based on the latest report by the King Commission. An important finding is that the cross cultural aspect of family business governance must now be considered when conducting such research as more and more emphasis is placed on the good governance of all businesses.
- Full Text:
- Date Issued: 2005
Marine anti-malarial isonitriles : a synthetic and computational study
- Authors: Adendorff, Matthew Ralph
- Date: 2011 , 2010-05-17
- Subjects: Isocyanides , Isocyanates , Marine pharmacology , Antimalarials , Antimalarials -- Development , Drug development
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4398 , http://hdl.handle.net/10962/d1006674 , Isocyanides , Isocyanates , Marine pharmacology , Antimalarials , Antimalarials -- Development , Drug development
- Description: The development of Plasmodium falciparum malarial resistance to the current armoury of anti-malarial drugs requires the development of new treatments to help combat this disease. The marine environment is a well established source of potential pharmaceuticals. Of interest to us are isonitrile, isocyanate and isothiocyanate compounds isolated from marine sponges and molluscs which have exhibited nano-molar anti-plasmodial activities. Through quantitative structure-activity relation studies (QSAR), a literature precedent exists for a pseudoreceptor model from which a pharmacophore for the design of novel anti-malarial agents was proposed. The current theory suggests that these marine compounds exert their inhibitory action through interfering with the heme detoxification pathway in P. falciparum. We propose that the computational methods used to draw detailed conclusions about the mode of action of these marine compounds were inadequate. This thesis addresses this problem using contemporary computational methodologies and seeks to propose a more robust method for the rational design of new anti-malarial drug compounds that inhibit heme polymerization to hemozoin. In order to investigate the interactions of the marine compounds with their heme targets, a series of modern computational procedures were formulated, validated and then applied to theoretical systems. The validations of these algorithms, before their application to the marine compound-heme systems, were achieved through two case studies. The first was used to investigate the applicability of the statistical docking algorithm AutoDock to be used for the exploration of conformational space around the heme target. A theoretical P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (PfDXR) enzyme model, constructed by the Biochemistry Department at Rhodes University, provided the ideal model to validate the AutoDock program. The protein model was accordingly subjected to rigorous docking simulations with over 30 different ligand molecules using the AutoDock algorithm which allowed for the docking algorithm’s limitations to be ascertained and improved upon. This investigation facilitated the successful validation of the protein model, which can now be used for the rational design of new PfDXR-inhibiting anti-plasmodial compounds, as well as enabling us to propose an improvement of the docking algorithm for application to the heme systems. The second case study was used to investigate the applicability of an ab initio molecular dynamics algorithm for simulation of bond breaking/forming events between the marine compounds and their heme target. This validation involved the exploration of intermolecular interactions in a naturally occurring nonoligomeric zipper using the Car-Parrinello Molecular Dynamics (CPMD) method. This study allowed us to propose a model for the intermolecular forces responsible for zipper self-assembly and showcased the CPMD method’s abilities to simulate and predict bond forming/breaking events. Data from the computational analyses suggested that the interactions between marine isonitriles, isocyanates and isothiocyanates occur through bond-less electrostatic attractions rather than through formal intermolecular bonds as had been previously suggested. Accordingly, a simple bicyclic tertiary isonitrile (5.14) was synthesized using Kitano et al’s relatively underutilized isonitrile synthetic method for the conversion of tertiary alcohols to their corresponding isonitriles. This compound’s potential for heme detoxification inhibition was then explored in vitro via the pyridine-hemochrome assay. The assay data suggested that the synthesized isonitrile was capable of inhibiting heme polymerization in a similar fashion to the known inhibitor chloroquine. Attempts to synthesize tricyclic analogues of 5.14 were unsuccessful and highlighted the limitation of Kitano et al’s isonitrile synthetic methodology.
- Full Text:
- Date Issued: 2011
- Authors: Adendorff, Matthew Ralph
- Date: 2011 , 2010-05-17
- Subjects: Isocyanides , Isocyanates , Marine pharmacology , Antimalarials , Antimalarials -- Development , Drug development
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4398 , http://hdl.handle.net/10962/d1006674 , Isocyanides , Isocyanates , Marine pharmacology , Antimalarials , Antimalarials -- Development , Drug development
- Description: The development of Plasmodium falciparum malarial resistance to the current armoury of anti-malarial drugs requires the development of new treatments to help combat this disease. The marine environment is a well established source of potential pharmaceuticals. Of interest to us are isonitrile, isocyanate and isothiocyanate compounds isolated from marine sponges and molluscs which have exhibited nano-molar anti-plasmodial activities. Through quantitative structure-activity relation studies (QSAR), a literature precedent exists for a pseudoreceptor model from which a pharmacophore for the design of novel anti-malarial agents was proposed. The current theory suggests that these marine compounds exert their inhibitory action through interfering with the heme detoxification pathway in P. falciparum. We propose that the computational methods used to draw detailed conclusions about the mode of action of these marine compounds were inadequate. This thesis addresses this problem using contemporary computational methodologies and seeks to propose a more robust method for the rational design of new anti-malarial drug compounds that inhibit heme polymerization to hemozoin. In order to investigate the interactions of the marine compounds with their heme targets, a series of modern computational procedures were formulated, validated and then applied to theoretical systems. The validations of these algorithms, before their application to the marine compound-heme systems, were achieved through two case studies. The first was used to investigate the applicability of the statistical docking algorithm AutoDock to be used for the exploration of conformational space around the heme target. A theoretical P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (PfDXR) enzyme model, constructed by the Biochemistry Department at Rhodes University, provided the ideal model to validate the AutoDock program. The protein model was accordingly subjected to rigorous docking simulations with over 30 different ligand molecules using the AutoDock algorithm which allowed for the docking algorithm’s limitations to be ascertained and improved upon. This investigation facilitated the successful validation of the protein model, which can now be used for the rational design of new PfDXR-inhibiting anti-plasmodial compounds, as well as enabling us to propose an improvement of the docking algorithm for application to the heme systems. The second case study was used to investigate the applicability of an ab initio molecular dynamics algorithm for simulation of bond breaking/forming events between the marine compounds and their heme target. This validation involved the exploration of intermolecular interactions in a naturally occurring nonoligomeric zipper using the Car-Parrinello Molecular Dynamics (CPMD) method. This study allowed us to propose a model for the intermolecular forces responsible for zipper self-assembly and showcased the CPMD method’s abilities to simulate and predict bond forming/breaking events. Data from the computational analyses suggested that the interactions between marine isonitriles, isocyanates and isothiocyanates occur through bond-less electrostatic attractions rather than through formal intermolecular bonds as had been previously suggested. Accordingly, a simple bicyclic tertiary isonitrile (5.14) was synthesized using Kitano et al’s relatively underutilized isonitrile synthetic method for the conversion of tertiary alcohols to their corresponding isonitriles. This compound’s potential for heme detoxification inhibition was then explored in vitro via the pyridine-hemochrome assay. The assay data suggested that the synthesized isonitrile was capable of inhibiting heme polymerization in a similar fashion to the known inhibitor chloroquine. Attempts to synthesize tricyclic analogues of 5.14 were unsuccessful and highlighted the limitation of Kitano et al’s isonitrile synthetic methodology.
- Full Text:
- Date Issued: 2011
Risk factors associated with developing asthma and tuberculosis : a case study of a hospital, Lagos Nigeria
- Authors: Adeniji, Tolulope Olubunmi
- Date: 2015
- Subjects: Asthma -- Nigeria -- Epidemiology Diseases -- Risk factors -- Nigeria
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/13216 , vital:39616
- Description: Purpose: The purpose of the study is to assess risk factors associated with developing asthma and tuberculosis. Methodology: A quantitative study was conducted on 133 randomly selected tuberculosis respondents, 91 of whom were suffering from TB at the time of the study. 120 respondents were also selected randomly for asthma of which 82 were asthmatic. Data were collected by using a self-structured questionnaire. The statistical analysis was done with the statistical package for social sciences (SPSS, version 18) using the descriptive statistics and logistic regression model. Results: Findings from the study show that a large percentage of the participants for both diseases were male, and the carriers of the diseases were also mostly male. Amongst the factors assessed, smoking, a weak immune system and a history of contact with tuberculosis infected persons were factors independently associated with developing tuberculosis. In the case of asthma, family history, smoking and exposure to allergen irritants were the factors independently associated with developing the disease. Conclusion: The findings highlight the need for increasing awareness through information, education and communication to address the risk factors of tuberculosis and asthma in order to decrease the rate of outspread. Recommendations: Factors triggering asthma among humans should be avoided. Since tuberculosis can be contracted through person to person contact, proper sanitation and regular medical attention are advocated for safeguarding personal and public health.
- Full Text:
- Date Issued: 2015
- Authors: Adeniji, Tolulope Olubunmi
- Date: 2015
- Subjects: Asthma -- Nigeria -- Epidemiology Diseases -- Risk factors -- Nigeria
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10353/13216 , vital:39616
- Description: Purpose: The purpose of the study is to assess risk factors associated with developing asthma and tuberculosis. Methodology: A quantitative study was conducted on 133 randomly selected tuberculosis respondents, 91 of whom were suffering from TB at the time of the study. 120 respondents were also selected randomly for asthma of which 82 were asthmatic. Data were collected by using a self-structured questionnaire. The statistical analysis was done with the statistical package for social sciences (SPSS, version 18) using the descriptive statistics and logistic regression model. Results: Findings from the study show that a large percentage of the participants for both diseases were male, and the carriers of the diseases were also mostly male. Amongst the factors assessed, smoking, a weak immune system and a history of contact with tuberculosis infected persons were factors independently associated with developing tuberculosis. In the case of asthma, family history, smoking and exposure to allergen irritants were the factors independently associated with developing the disease. Conclusion: The findings highlight the need for increasing awareness through information, education and communication to address the risk factors of tuberculosis and asthma in order to decrease the rate of outspread. Recommendations: Factors triggering asthma among humans should be avoided. Since tuberculosis can be contracted through person to person contact, proper sanitation and regular medical attention are advocated for safeguarding personal and public health.
- Full Text:
- Date Issued: 2015
Analysis of the security and reliability of packet transmission in Wireless Mesh Networks (WMNs) : a case study of Malicious Packet drop attack
- Adeniji, Victor Oluwatobiloba
- Authors: Adeniji, Victor Oluwatobiloba
- Date: 2018
- Subjects: Wireless communication systems Mobile communication systems
- Language: English
- Type: Thesis , Masters , Computer Science
- Identifier: http://hdl.handle.net/10353/17450 , vital:40969
- Description: Wireless Mesh Networks (WMNs) are known for possessing good attributes such as low up-front cost, easy network maintenance, and reliable service coverage. This has largely made them to be adopted in various areas such as; school campus networks, community networking, pervasive healthcare, office and home automation, emergency rescue operations and ubiquitous wireless networks. The routing nodes are equipped with self-organized and self-configuring capabilities. The routing mechanisms of WMNs depend on the collaboration of all participating nodes for reliable network performance. However, it has been noted that most routing algorithms proposed for WMNs in the last few years are designed with the assumption that all the participating nodes will collaboratively be involved in relaying the data packets originated from a source to a multi-hop destination. Such design approach exposes WMNs to vulnerability such as malicious packet drop attack. Therefore, it is imperative to design and implement secure and reliable packet routing mechanisms to mitigate this type of attack. While there are works that have attempted to implement secure routing approach, the findings in this research unearthed that further research works are required to improve the existing secure routing in order to provide more secure and reliable packet transmission in WMNs, in the event of denial of service (DoS) attacks such black hole malicious pack drop attack. This study further presents an analysis of the impact of the black hole malicious packet drop attack with other influential factors in WMNs. In the study, NS-3 simulator was used with AODV as the routing protocol. The results show that the packet delivery ratio and throughput of WMN under attack decreases sharply as compared to WMN free from attack.
- Full Text:
- Date Issued: 2018
- Authors: Adeniji, Victor Oluwatobiloba
- Date: 2018
- Subjects: Wireless communication systems Mobile communication systems
- Language: English
- Type: Thesis , Masters , Computer Science
- Identifier: http://hdl.handle.net/10353/17450 , vital:40969
- Description: Wireless Mesh Networks (WMNs) are known for possessing good attributes such as low up-front cost, easy network maintenance, and reliable service coverage. This has largely made them to be adopted in various areas such as; school campus networks, community networking, pervasive healthcare, office and home automation, emergency rescue operations and ubiquitous wireless networks. The routing nodes are equipped with self-organized and self-configuring capabilities. The routing mechanisms of WMNs depend on the collaboration of all participating nodes for reliable network performance. However, it has been noted that most routing algorithms proposed for WMNs in the last few years are designed with the assumption that all the participating nodes will collaboratively be involved in relaying the data packets originated from a source to a multi-hop destination. Such design approach exposes WMNs to vulnerability such as malicious packet drop attack. Therefore, it is imperative to design and implement secure and reliable packet routing mechanisms to mitigate this type of attack. While there are works that have attempted to implement secure routing approach, the findings in this research unearthed that further research works are required to improve the existing secure routing in order to provide more secure and reliable packet transmission in WMNs, in the event of denial of service (DoS) attacks such black hole malicious pack drop attack. This study further presents an analysis of the impact of the black hole malicious packet drop attack with other influential factors in WMNs. In the study, NS-3 simulator was used with AODV as the routing protocol. The results show that the packet delivery ratio and throughput of WMN under attack decreases sharply as compared to WMN free from attack.
- Full Text:
- Date Issued: 2018
The role of custodial grandparents in psychosocial well-being of adolescents from single parents in Buffalo City Municipality of Eastern Cape, South Africa
- Authors: Adenike,Folorunsho Fausat
- Date: 2020
- Subjects: Grandparents as parents Grandparent and child Grandparenting
- Language: English
- Type: Thesis , Doctoral , PhD(Social Work)
- Identifier: http://hdl.handle.net/10353/17943 , vital:41994
- Description: It has been a historical norm in African societies for children to leave in the homes of caregivers. Among these caregivers are the grandparents, who are from time immemorial, being a pillar of support to their children in caring for their grandchildren. Against this background, the study assesses custodial the role of grandparents in the psychosocial well-being of adolescent children from single parents' homes in Buffalo City Metropolitan Municipality, Eastern Cape Province, South Africa. The study was guided theoretically by Role and Ryff's psychosocial well-being theories. Four sets of participants totaling 323 gathered using a mixed-method approach comprised of 150 adolescents and 136 custodial grandparents through questionnaires, 30 single parents, through in-depth interviews, and seven social workers through focus group discussions. The study utilized a multi-stage sampling technique to select adolescents and their grandparents, a purposive sampling technique for single parents, and a convenient sampling technique for social workers. The quantitative data were analyzed using descriptive statistics and Pearson's Correlation Coefficient, while the qualitative data were categorized manually into themes and subthemes. Findings indicated a correlation between the attainment of the adolescent children's psychosocial well-being and the effectiveness of the custodial grandparents' role. More also, the challenges encountered by custodial grandparents do affect the attainment of the psychosocial well-being of adolescent children. Furthermore, finding from the study revealed that non-governmental organizations in the municipality were not rendering social support for the custodial grandparents. Finally, the child-support grant received by poor grandparents is grossly inadequate to meet up with the astronomical needs of the adolescent children. The study concluded that custodial grandparents' social support is an effective mechanism in meeting adolescent children's psychosocial well-being. Several recommendations were made from the conclusions to various stakeholders and proposed a responsive conceptual grand-parenting model to cater for effective parenting.
- Full Text:
- Date Issued: 2020
- Authors: Adenike,Folorunsho Fausat
- Date: 2020
- Subjects: Grandparents as parents Grandparent and child Grandparenting
- Language: English
- Type: Thesis , Doctoral , PhD(Social Work)
- Identifier: http://hdl.handle.net/10353/17943 , vital:41994
- Description: It has been a historical norm in African societies for children to leave in the homes of caregivers. Among these caregivers are the grandparents, who are from time immemorial, being a pillar of support to their children in caring for their grandchildren. Against this background, the study assesses custodial the role of grandparents in the psychosocial well-being of adolescent children from single parents' homes in Buffalo City Metropolitan Municipality, Eastern Cape Province, South Africa. The study was guided theoretically by Role and Ryff's psychosocial well-being theories. Four sets of participants totaling 323 gathered using a mixed-method approach comprised of 150 adolescents and 136 custodial grandparents through questionnaires, 30 single parents, through in-depth interviews, and seven social workers through focus group discussions. The study utilized a multi-stage sampling technique to select adolescents and their grandparents, a purposive sampling technique for single parents, and a convenient sampling technique for social workers. The quantitative data were analyzed using descriptive statistics and Pearson's Correlation Coefficient, while the qualitative data were categorized manually into themes and subthemes. Findings indicated a correlation between the attainment of the adolescent children's psychosocial well-being and the effectiveness of the custodial grandparents' role. More also, the challenges encountered by custodial grandparents do affect the attainment of the psychosocial well-being of adolescent children. Furthermore, finding from the study revealed that non-governmental organizations in the municipality were not rendering social support for the custodial grandparents. Finally, the child-support grant received by poor grandparents is grossly inadequate to meet up with the astronomical needs of the adolescent children. The study concluded that custodial grandparents' social support is an effective mechanism in meeting adolescent children's psychosocial well-being. Several recommendations were made from the conclusions to various stakeholders and proposed a responsive conceptual grand-parenting model to cater for effective parenting.
- Full Text:
- Date Issued: 2020
A management model for human settlements: a case study of Nigeria and South Africa
- Authors: Adeniran, Adeleye Ayoade
- Date: 2020
- Subjects: Human settlements -- Nigeria , Human settlements -- South Africa Sustainable development
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/45985 , vital:39403
- Description: Persistent depreciating human settlements is a global challenge, particularly in developing countries and this challenge contributes to the continuously increasing housing gap, despite several novel policies and programmes. Although there is a dearth of research-based literature on human settlements management, studies show that property management, Facility Management, housing management and urban management impact the sustainability of all these built environment milieus which form part of the human settlements’ sub-components. This research aimed at altering the afore-said challenge by exploring the management of human settlements in Nigeria and in South Africa. Philosophically, the research is pragmatic, and it rests on positivist deductive reasoning. The methods used for data collection include a review of literature, collection of archival records, and empirical studies of purposively selected professionals and stakeholders involved in human settlements’ management in Nigeria and in South Africa. The findings indicate that existing human settlements in the case studies are “good” and “acceptable” with the majority adopting an outsourced method of management. Furthermore, the lack of maintenance records, the deficiency in policy monitoring and the training of management and maintenance personnel were the three highest ranking factors indicated to be affecting human settlements management. Moreover, an inhabitant’s income, the time available for management, professional expertise and technology employed for management are recognised as the critical sustainability sub-factors affecting human settlement management. The factor analysis established ownership, human resource and capital, social, legal, technology, economic, physical and environmental factors as vital and very significant in achieving sustainable management of human settlements. The study recommends the professionalisation of the field of human settlements as well as a formulation of management policy among others. The study developed a management model for human settlements, and it advocates that human settlements managers, owners and organisations should apply the model in this study, to improve their human settlement management practices, so as to achieve sustainability, and in essence, Sustainable Development Goal 11. It is hoped that the suggested management model will influence human settlement policy development and review, the designing of human settlement management programmes including the framework for their ongoing monitoring and evaluation. The study furthermore contributes to the development of housing and human settlement curricula and evolving human settlement research in both developed and developing countries.
- Full Text:
- Date Issued: 2020
- Authors: Adeniran, Adeleye Ayoade
- Date: 2020
- Subjects: Human settlements -- Nigeria , Human settlements -- South Africa Sustainable development
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/45985 , vital:39403
- Description: Persistent depreciating human settlements is a global challenge, particularly in developing countries and this challenge contributes to the continuously increasing housing gap, despite several novel policies and programmes. Although there is a dearth of research-based literature on human settlements management, studies show that property management, Facility Management, housing management and urban management impact the sustainability of all these built environment milieus which form part of the human settlements’ sub-components. This research aimed at altering the afore-said challenge by exploring the management of human settlements in Nigeria and in South Africa. Philosophically, the research is pragmatic, and it rests on positivist deductive reasoning. The methods used for data collection include a review of literature, collection of archival records, and empirical studies of purposively selected professionals and stakeholders involved in human settlements’ management in Nigeria and in South Africa. The findings indicate that existing human settlements in the case studies are “good” and “acceptable” with the majority adopting an outsourced method of management. Furthermore, the lack of maintenance records, the deficiency in policy monitoring and the training of management and maintenance personnel were the three highest ranking factors indicated to be affecting human settlements management. Moreover, an inhabitant’s income, the time available for management, professional expertise and technology employed for management are recognised as the critical sustainability sub-factors affecting human settlement management. The factor analysis established ownership, human resource and capital, social, legal, technology, economic, physical and environmental factors as vital and very significant in achieving sustainable management of human settlements. The study recommends the professionalisation of the field of human settlements as well as a formulation of management policy among others. The study developed a management model for human settlements, and it advocates that human settlements managers, owners and organisations should apply the model in this study, to improve their human settlement management practices, so as to achieve sustainability, and in essence, Sustainable Development Goal 11. It is hoped that the suggested management model will influence human settlement policy development and review, the designing of human settlement management programmes including the framework for their ongoing monitoring and evaluation. The study furthermore contributes to the development of housing and human settlement curricula and evolving human settlement research in both developed and developing countries.
- Full Text:
- Date Issued: 2020
Computational studies, synthesis and characterization of ruthenium (ii) anticancer complexes
- Authors: Adeniyi, Adebayo Azeez
- Date: 2014
- Language: English
- Type: Thesis , Doctoral , PhD (Chemistry)
- Identifier: vital:11338 , http://hdl.handle.net/10353/d1015577
- Description: This thesis is centred on the application of Ru-based complexes as a promising alternative to cis-platin in cancer chemotherapy. Cis-platin is known to be the most prescribed chemotherapy which has more than 70% application in cancer cases especially the testicular cancer. An insight is provided in Chapter One and Two into the literatures reports on the application of Ru(II)-based complexes in cancer chemotherapy. In order to address some of the pressing challenges in rational design of Ru-based anticancer complexes, section 3.3 and 3.4 deal with efforts to elucidate the complication of their chemistry and instability while in section 3.5 efforts are made to find solution to the lack of proper knowledge of their targets using different theoretical approaches as presented in Chapter Three. In addition to the theoretical study, this thesis also comprises of the synthesis of the bis-pyrazole derivatives type of ligands and the derivatives of their Ru(II)-based complexes as provided in Chapter Four and Five respectively. Also the computational methods were used to elucidate the structural and spectroscopic properties of the synthesised ligands and their Ru(II)-based complexes. The geometrical and electronic properties are studied in relation to the stability and the reported anticancer activities of Ru(II)-based complexes in section 3.3. In subsection 3.3.1, several quantum properties including the natural energy decomposition analysis (NEDA) and quantum theory of atoms in a molecule (QTAIM) are computed on three models of RAPTA-C complexes using DFT with hybrid functional and basis set with ECP and without ECP. The higher stability of Carbo-RAPTA-C and Oxalo-RAPTA-C over RAPTA-C comes from the lower exchange repulsion and higher polarization contributions to their stability which gives insight into experimental observation. A similar study was carried out in subsection 3.3.2 on half-sandwich Ru(II)-based anticancer complexes with 6-toluene and 6-trifluorotoluene.
- Full Text:
- Date Issued: 2014
- Authors: Adeniyi, Adebayo Azeez
- Date: 2014
- Language: English
- Type: Thesis , Doctoral , PhD (Chemistry)
- Identifier: vital:11338 , http://hdl.handle.net/10353/d1015577
- Description: This thesis is centred on the application of Ru-based complexes as a promising alternative to cis-platin in cancer chemotherapy. Cis-platin is known to be the most prescribed chemotherapy which has more than 70% application in cancer cases especially the testicular cancer. An insight is provided in Chapter One and Two into the literatures reports on the application of Ru(II)-based complexes in cancer chemotherapy. In order to address some of the pressing challenges in rational design of Ru-based anticancer complexes, section 3.3 and 3.4 deal with efforts to elucidate the complication of their chemistry and instability while in section 3.5 efforts are made to find solution to the lack of proper knowledge of their targets using different theoretical approaches as presented in Chapter Three. In addition to the theoretical study, this thesis also comprises of the synthesis of the bis-pyrazole derivatives type of ligands and the derivatives of their Ru(II)-based complexes as provided in Chapter Four and Five respectively. Also the computational methods were used to elucidate the structural and spectroscopic properties of the synthesised ligands and their Ru(II)-based complexes. The geometrical and electronic properties are studied in relation to the stability and the reported anticancer activities of Ru(II)-based complexes in section 3.3. In subsection 3.3.1, several quantum properties including the natural energy decomposition analysis (NEDA) and quantum theory of atoms in a molecule (QTAIM) are computed on three models of RAPTA-C complexes using DFT with hybrid functional and basis set with ECP and without ECP. The higher stability of Carbo-RAPTA-C and Oxalo-RAPTA-C over RAPTA-C comes from the lower exchange repulsion and higher polarization contributions to their stability which gives insight into experimental observation. A similar study was carried out in subsection 3.3.2 on half-sandwich Ru(II)-based anticancer complexes with 6-toluene and 6-trifluorotoluene.
- Full Text:
- Date Issued: 2014
Genetic diversity, resistance profile of hiv and risk assessment of mother-to-child transmission in pregnant women on antiretroviral therapy in the Eastern Cape, South Africa
- Authors: Adeniyi, Oladele Vincent
- Date: 2019
- Subjects: Antiretroviral agents HIV infections -- Treatment -- South Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/15120 , vital:40183
- Description: Despite the initiation of life-long ART in HIV-infected pregnant women, the rate and determinants of infant HIV transmission are not known, especially in the poor resource settings of the Eastern Cape, South Africa. Maternal anti-retroviral therapy (ART) is crucial for elimination of mother-to-child transmission (MTCT) of HIV. However, the inevitable risks of emergence of HIV drug resistance poses significant threat to achieving this goal of HIV-free generation and keeping mothers alive. Also, it is unclear if women with high viral load at delivery have acquired clinically relevant mutations, which could confer resistance to the ART, thus, further increasing the risks of motherto-child transmission of HIV-drug resistance strains. In addition to the gaps identified in the prevention of mother-to-child transmission (PMTCT) context, the understanding of regional epidemics is crucial to the broader epidemiological profiling of HIV infections in the country. Despite the rapid influx of foreign nationals to South African and Eastern Cape Province, there has not been any molecular epidemiological studies profiling the HIV diversity in the Eastern Cape.
- Full Text:
- Date Issued: 2019
- Authors: Adeniyi, Oladele Vincent
- Date: 2019
- Subjects: Antiretroviral agents HIV infections -- Treatment -- South Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/15120 , vital:40183
- Description: Despite the initiation of life-long ART in HIV-infected pregnant women, the rate and determinants of infant HIV transmission are not known, especially in the poor resource settings of the Eastern Cape, South Africa. Maternal anti-retroviral therapy (ART) is crucial for elimination of mother-to-child transmission (MTCT) of HIV. However, the inevitable risks of emergence of HIV drug resistance poses significant threat to achieving this goal of HIV-free generation and keeping mothers alive. Also, it is unclear if women with high viral load at delivery have acquired clinically relevant mutations, which could confer resistance to the ART, thus, further increasing the risks of motherto-child transmission of HIV-drug resistance strains. In addition to the gaps identified in the prevention of mother-to-child transmission (PMTCT) context, the understanding of regional epidemics is crucial to the broader epidemiological profiling of HIV infections in the country. Despite the rapid influx of foreign nationals to South African and Eastern Cape Province, there has not been any molecular epidemiological studies profiling the HIV diversity in the Eastern Cape.
- Full Text:
- Date Issued: 2019
Active learning strategies used by teachers during English reading comprehension lessons in six selected primary schools in Nigeria
- Adepoju, Adetokunboh Abayomi
- Authors: Adepoju, Adetokunboh Abayomi
- Date: 2018
- Subjects: Education, Primary -- Nigeria Learning strategies -- Nigeria
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/8485 , vital:32838
- Description: Reading is an integral part of education from which one gets access to information. Unfortunately, reading ability among primary school pupils, the foundation level of education, is at its lowest ebb. These pupils when they get to secondary schools eventually fail external examinations-a situation which according to National Examination Council, is caused by inappropriate teaching methods. Consequent upon this, this study assessed active learning strategies used by teacher during English reading comprehension lessons in six selected primary schools in Nigeria. The main research question was: How do teachers employ active learning strategies in teaching English reading comprehension? The study adopted qualitative approach and case study design. With the use of purposive sampling technique to select six head teachers, six primary VI teachers, two members of the School Basic Committee, the Director Local Government Education Authority and six focus groups. The study used interviews, documents and focus group interview as research instruments to collect data. Data were analysed based on interpretivism paradigm which interpreted participants’ views according to the word view of the participants. The study found out that teachers have good knowledge of active learning strategies and use them in teaching English reading comprehension lessons but are faced with some daunting challenges such as non-availability of instructional materials, lack of library, lack of qualified teachers and lack of time. The study concluded that students fail woefully in English reading comprehension because teachers do not use appropriate teaching techniques. The study recommend that teachers must use active learning strategies effectively and more often during English reading comprehension, more time should be allocated for English reading comprehension, effective use of instructional materials should be considered and the government should employ specialist teachers to teach English reading comprehension.
- Full Text:
- Date Issued: 2018
- Authors: Adepoju, Adetokunboh Abayomi
- Date: 2018
- Subjects: Education, Primary -- Nigeria Learning strategies -- Nigeria
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/8485 , vital:32838
- Description: Reading is an integral part of education from which one gets access to information. Unfortunately, reading ability among primary school pupils, the foundation level of education, is at its lowest ebb. These pupils when they get to secondary schools eventually fail external examinations-a situation which according to National Examination Council, is caused by inappropriate teaching methods. Consequent upon this, this study assessed active learning strategies used by teacher during English reading comprehension lessons in six selected primary schools in Nigeria. The main research question was: How do teachers employ active learning strategies in teaching English reading comprehension? The study adopted qualitative approach and case study design. With the use of purposive sampling technique to select six head teachers, six primary VI teachers, two members of the School Basic Committee, the Director Local Government Education Authority and six focus groups. The study used interviews, documents and focus group interview as research instruments to collect data. Data were analysed based on interpretivism paradigm which interpreted participants’ views according to the word view of the participants. The study found out that teachers have good knowledge of active learning strategies and use them in teaching English reading comprehension lessons but are faced with some daunting challenges such as non-availability of instructional materials, lack of library, lack of qualified teachers and lack of time. The study concluded that students fail woefully in English reading comprehension because teachers do not use appropriate teaching techniques. The study recommend that teachers must use active learning strategies effectively and more often during English reading comprehension, more time should be allocated for English reading comprehension, effective use of instructional materials should be considered and the government should employ specialist teachers to teach English reading comprehension.
- Full Text:
- Date Issued: 2018
Adoption and risk of mobile financial services: a case of some selected municipalities in Eastern Cape Province
- Authors: Aderibigbe, Ifeoluwa A.I
- Date: 2019
- Subjects: Mobile commerce Finance
- Language: English
- Type: Thesis , Masters , MCom (Economics)
- Identifier: http://hdl.handle.net/10353/13281 , vital:39630
- Description: The study investigated risk and adoption of mobile financial services among some users in selected municipalities within the Eastern Cape Province, using the theory of reason action, technology acceptance model and the theory of expected utility and risk aversion to explain the variables. Moreover, the explanatory research design and quantitative data collection approach formed the methodology adopted in the study. In addition, a validated semistructured interview questionnaire was used as a research instrument in the study. The multistage, stratify, purposive and convenience sampling techniques were applied to select 6 research sites and 386 research participants for the study. Three research objectives were stated and tested using descriptive, Principal Component Analysis (PCA) to profile the risk and logit regression statistics. The results of statistical analysis show different level of cross tabulation between MFS and education level, all the 6 different locations, individual age range, job type, and average income of individual. Analysis revealed that age and income level of individuals have the highest relationship with the use of MFS. The statistical analysis used was the logistic regression. Pool of effort of all the stake holders in financial services sector should focus on including the low income earners and the technology should be simple enough for the use of the older generation.
- Full Text:
- Date Issued: 2019
- Authors: Aderibigbe, Ifeoluwa A.I
- Date: 2019
- Subjects: Mobile commerce Finance
- Language: English
- Type: Thesis , Masters , MCom (Economics)
- Identifier: http://hdl.handle.net/10353/13281 , vital:39630
- Description: The study investigated risk and adoption of mobile financial services among some users in selected municipalities within the Eastern Cape Province, using the theory of reason action, technology acceptance model and the theory of expected utility and risk aversion to explain the variables. Moreover, the explanatory research design and quantitative data collection approach formed the methodology adopted in the study. In addition, a validated semistructured interview questionnaire was used as a research instrument in the study. The multistage, stratify, purposive and convenience sampling techniques were applied to select 6 research sites and 386 research participants for the study. Three research objectives were stated and tested using descriptive, Principal Component Analysis (PCA) to profile the risk and logit regression statistics. The results of statistical analysis show different level of cross tabulation between MFS and education level, all the 6 different locations, individual age range, job type, and average income of individual. Analysis revealed that age and income level of individuals have the highest relationship with the use of MFS. The statistical analysis used was the logistic regression. Pool of effort of all the stake holders in financial services sector should focus on including the low income earners and the technology should be simple enough for the use of the older generation.
- Full Text:
- Date Issued: 2019
Psychological capital and emotional intelligence as moderators of the relationship between occupational stress and organisational citizenship behaviour among graduate employees in Nigeria
- Authors: Aderibigbe, John Kolawole
- Date: 2017
- Subjects: Psychology, Industrial Emotional intelligence
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/8642 , vital:33250
- Description: The study investigated psychological capital and emotional intelligence as moderators of the relationship between occupational stress and organisational citizenship behaviour among graduate employees in Nigeria, using the explanatory cross-sectional (survey) research design and three sampling techniques (The Two-stage Cluster Sampling Method, The Convenience Sampling Method and The Purposive Sampling Technique) to sample 1532 male and female graduate employees in Nigeria. A structured validated questionnaire was used to collect data from the respondents. Six hypotheses were stated and tested in the study towards propounding a model, using Pearson Correlation Analysis, Multiple Regression Analysis and Structural Equation Modelling. The results show that there is a weak positive relationship between occupational stress and organisational citizenship behaviour, r = 0.070, p<0.01; there is a significant positive relationship between psychological capital and organisational citizenship behaviour, r = 0.588, p<0.01; there is a significant positive relationship between emotional intelligence and organisational citizenship behaviour, r = 0.473, p<0.01; psychological capital is a significant moderator of the relationship between occupational stress and organisational citizenship behaviour, F (2,1529) = 8.514; R2= 0.011; p <.05; emotional intelligence is a significant moderator of the relationship between occupational stress and organisational citizenship behaviour, F (2,1529) = 5.945; R2= 0.008; p <.05; psychological capital and emotional intelligence are significant joint moderators of the relationship between occupational stress and organisational citizenship behaviour, F (1,1530) = 221.240; R2= 0.186; p <.05; psychological capital has a direct and significant positive effect on organisational citizenship behaviour, R= 0.657, p<.001; emotional intelligence has a direct and significant positive effect on organisational citizenship behaviour, R= 0.183, p<.001; psychological capital has a direct and significant positive effect on occupational stress, R= 0.100, p<.001; emotional intelligence has a direct and significant positive effect on psychological capital, R= 0.547, p<.001. Based on the results, the study concludes that psychological capital and emotional intelligence are significant joint moderators of the relationship between occupational stress and organisational citizenship behaviour. The proposed model was, therefore, empirically confirmed. The researcher recommends that the empirical model of effective management of occupational stress and organisational citizenship behaviour, which has been propounded in the study, should be adopted and applied by teachers, lecturers, seminar facilitators, workshop trainers, supervisors and managers during their coaching or training sessions.
- Full Text:
- Date Issued: 2017
- Authors: Aderibigbe, John Kolawole
- Date: 2017
- Subjects: Psychology, Industrial Emotional intelligence
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/8642 , vital:33250
- Description: The study investigated psychological capital and emotional intelligence as moderators of the relationship between occupational stress and organisational citizenship behaviour among graduate employees in Nigeria, using the explanatory cross-sectional (survey) research design and three sampling techniques (The Two-stage Cluster Sampling Method, The Convenience Sampling Method and The Purposive Sampling Technique) to sample 1532 male and female graduate employees in Nigeria. A structured validated questionnaire was used to collect data from the respondents. Six hypotheses were stated and tested in the study towards propounding a model, using Pearson Correlation Analysis, Multiple Regression Analysis and Structural Equation Modelling. The results show that there is a weak positive relationship between occupational stress and organisational citizenship behaviour, r = 0.070, p<0.01; there is a significant positive relationship between psychological capital and organisational citizenship behaviour, r = 0.588, p<0.01; there is a significant positive relationship between emotional intelligence and organisational citizenship behaviour, r = 0.473, p<0.01; psychological capital is a significant moderator of the relationship between occupational stress and organisational citizenship behaviour, F (2,1529) = 8.514; R2= 0.011; p <.05; emotional intelligence is a significant moderator of the relationship between occupational stress and organisational citizenship behaviour, F (2,1529) = 5.945; R2= 0.008; p <.05; psychological capital and emotional intelligence are significant joint moderators of the relationship between occupational stress and organisational citizenship behaviour, F (1,1530) = 221.240; R2= 0.186; p <.05; psychological capital has a direct and significant positive effect on organisational citizenship behaviour, R= 0.657, p<.001; emotional intelligence has a direct and significant positive effect on organisational citizenship behaviour, R= 0.183, p<.001; psychological capital has a direct and significant positive effect on occupational stress, R= 0.100, p<.001; emotional intelligence has a direct and significant positive effect on psychological capital, R= 0.547, p<.001. Based on the results, the study concludes that psychological capital and emotional intelligence are significant joint moderators of the relationship between occupational stress and organisational citizenship behaviour. The proposed model was, therefore, empirically confirmed. The researcher recommends that the empirical model of effective management of occupational stress and organisational citizenship behaviour, which has been propounded in the study, should be adopted and applied by teachers, lecturers, seminar facilitators, workshop trainers, supervisors and managers during their coaching or training sessions.
- Full Text:
- Date Issued: 2017
Staff perceptions of workplace bullying in a South African higher education institution
- Authors: Adesemowo, Bosede Olaitan
- Date: 2018
- Subjects: Bullying in the workplace , Harassment Work environment
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/23404 , vital:30539
- Description: During the past decade bullying has received growing attention in organizational research. Workplace bullying is a complex phenomenon with a variety of situational, dispositional and systemic influences and it has been defined as “status-blind interpersonal hostility that is deliberate, repeated and sufficiently severe as to harm the targeted person's health or economic status” (Namie, 2003:3). A literature overview revealed the destructive consequences of bullying, such as trauma, suicide, depression, anxiety, stress, lowered self-esteem, anger and a lessening of productivity for both the individuals and the organizations concerned. This study presents the perceptions of staff members, in the form of recognized trade union representatives, of workplace bullying at the Nelson Mandela Metropolitan University. The theoretical framework that informed the study comprised the dispositional and the ecological model that emphasised Ubuntu and the cultural values of the University. The research approach was carried out through qualitative and exploratory methods. Through primary and secondary data collection, a purposive sample of semi-structured interviews was collected in the context of the aim and the objectives of the study. It analysed the importance of an anti-bullying policy, management styles, power imbalances, the impact of bullying on staff and institution health and explored the existing supportive systems that deal with grievances procedures. This study concludes with concrete evidence that workplace bullying existed in Nelson Mandela University and there were no policies to effect control over perpetrators’ acts. Based on the findings of the study, recommendations are made regarding a strategy on how management can effectively address bullying complaints without prejudice and discrimination, such as an anti-bullying policy, and creating continuous awareness of the phenomenon.
- Full Text:
- Date Issued: 2018
- Authors: Adesemowo, Bosede Olaitan
- Date: 2018
- Subjects: Bullying in the workplace , Harassment Work environment
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/23404 , vital:30539
- Description: During the past decade bullying has received growing attention in organizational research. Workplace bullying is a complex phenomenon with a variety of situational, dispositional and systemic influences and it has been defined as “status-blind interpersonal hostility that is deliberate, repeated and sufficiently severe as to harm the targeted person's health or economic status” (Namie, 2003:3). A literature overview revealed the destructive consequences of bullying, such as trauma, suicide, depression, anxiety, stress, lowered self-esteem, anger and a lessening of productivity for both the individuals and the organizations concerned. This study presents the perceptions of staff members, in the form of recognized trade union representatives, of workplace bullying at the Nelson Mandela Metropolitan University. The theoretical framework that informed the study comprised the dispositional and the ecological model that emphasised Ubuntu and the cultural values of the University. The research approach was carried out through qualitative and exploratory methods. Through primary and secondary data collection, a purposive sample of semi-structured interviews was collected in the context of the aim and the objectives of the study. It analysed the importance of an anti-bullying policy, management styles, power imbalances, the impact of bullying on staff and institution health and explored the existing supportive systems that deal with grievances procedures. This study concludes with concrete evidence that workplace bullying existed in Nelson Mandela University and there were no policies to effect control over perpetrators’ acts. Based on the findings of the study, recommendations are made regarding a strategy on how management can effectively address bullying complaints without prejudice and discrimination, such as an anti-bullying policy, and creating continuous awareness of the phenomenon.
- Full Text:
- Date Issued: 2018
Apparent digestibility coefficients of feed ingredients and essential amino acid requirements of dusky kob (Argyrosomus japonicus)
- Authors: Adesola, Abidemi Adejoke
- Date: 2017
- Subjects: Amino acids in animal nutrition , Fishes -- Feeding and feeds , Argyrosomus japonicus , Argyrosomus , Argyrosomus japonicus -- Nutrition , Argyrosomus -- Nutrition , Argyrosomus japonicus -- Feeding and feeds , Argyrosomus -- Feeding and feeds
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/32140 , vital:24014
- Description: Important to the evaluation of potential feed ingredients for inclusion in fish diets should be their digestibility and amino acid requirement so that feeds can be formulated on a digestible basis rather than a gross nutrient basis. This thesis established techniques for faecal collection, the validity of digestibility markers, it determined apparent digestibility coefficients for various novel feed ingredients, and it established the optimal lysine requirement for Argyrosomus japonicus, which was used to estimate each of the essential amino acid requirements by using the ideal protein concept. There were no significant differences in dry matter apparent digestibility coefficients when faeces were collected by stripping (77.0 %), dissection (80.1 %) or settlement (83.5 %). Faecal collection by the settlement method produced the most reliable digestibility data. Apparent digestibility coefficients for dry matter, crude protein and energy calculated using acid-insoluble ash were higher (84.0 %, 93.2 % and 93.0 %, respectively) than those using chromic oxide (55.7 %, 79.1 % and 78.2 %) and titanium dioxide (58.6 %, 79.7 % and 80.5 %). The magnitude of variation in digestibility coefficients obtained using acid-insoluble ash was always lower than that obtained with the other markers. Therefore, acid-insoluble ash was preferred as a dietary marker. Using the above protocol, protein and amino acid digestibility of some animal and plant protein ingredients were evaluated in a series of experiments. The first trial compared the apparent digestibility coefficients of some animal products included as single protein source in the test diets. Apparent protein digestibility values were 84.5 %, 83.8 %, 85.8 % and 83.1 % for fishmeal-prime, fishmeal-standard, poultry meal and pork meal, respectively. Apparent digestibility coefficients for poultry meal were comparable to those of fishmeal, which indicate its potential as a substitute for fishmeal in the diets of A. japonicus. The second trial determined the apparent coefficients of plant and animal protein sources included at 30 % into a practical reference diet (70 %). Apparent protein digestibility ranged from 92.4 % in sunflower meal to 85.5 % in corn gluten meal. Soybean meal is a promising feed ingredient in A. japonicus due to the high apparent digestibility of its protein (92.0 %) and essential amino acid digestibility (mean average 91.4 %). A fundamental assumption in fish feed formulation is that the digestibility of nutrients is additive, i.e., digestibility of a nutrient in one ingredient does not interact with the digestibility of the same nutrient in another ingredient. In the third trial, additivity of feed ingredients was tested using pork meal and poultry meal. The results indicate that the apparent digestibility coefficient of animal protein ingredients could be calculated from compound diets to accurately determine protein and amino acid digestibility in A. japonicus, and possibly other carnivorous fish species. Dietary essential amino acid requirements were determined for juvenile A. japonicus in two trials. A dose-response study was conducted using crystalline lysine to determine the optimal requirement of dietary lysine for A. japonicus. Optimal dietary lysine was estimated at 31.7 g kg-¹ dry diet, corresponding to 73.5 g kg-¹ of dietary protein, based on specific growth rate and broken-line segmented regression analyses. Dietary requirements for other essential amino acids ranged from 22 g kg-¹ (histidine) to 71 g kg-¹ (leucine) crude protein. The results of the present study provided a research tool that could be used to assess and verify the conclusions of earlier dietary work on A. japonicus and in further studies to develop least cost diet formulations for this species. The study also adds to the knowledge of the nutritional requirements of A. japonicus by providing information on the digestibility of plants and animal protein ingredients. It also contributes to future dietary research for this species because this study determines, for the first time, the most suitable methods for investigating the digestibility of raw materials for A. japonicus.
- Full Text:
- Date Issued: 2017
- Authors: Adesola, Abidemi Adejoke
- Date: 2017
- Subjects: Amino acids in animal nutrition , Fishes -- Feeding and feeds , Argyrosomus japonicus , Argyrosomus , Argyrosomus japonicus -- Nutrition , Argyrosomus -- Nutrition , Argyrosomus japonicus -- Feeding and feeds , Argyrosomus -- Feeding and feeds
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/32140 , vital:24014
- Description: Important to the evaluation of potential feed ingredients for inclusion in fish diets should be their digestibility and amino acid requirement so that feeds can be formulated on a digestible basis rather than a gross nutrient basis. This thesis established techniques for faecal collection, the validity of digestibility markers, it determined apparent digestibility coefficients for various novel feed ingredients, and it established the optimal lysine requirement for Argyrosomus japonicus, which was used to estimate each of the essential amino acid requirements by using the ideal protein concept. There were no significant differences in dry matter apparent digestibility coefficients when faeces were collected by stripping (77.0 %), dissection (80.1 %) or settlement (83.5 %). Faecal collection by the settlement method produced the most reliable digestibility data. Apparent digestibility coefficients for dry matter, crude protein and energy calculated using acid-insoluble ash were higher (84.0 %, 93.2 % and 93.0 %, respectively) than those using chromic oxide (55.7 %, 79.1 % and 78.2 %) and titanium dioxide (58.6 %, 79.7 % and 80.5 %). The magnitude of variation in digestibility coefficients obtained using acid-insoluble ash was always lower than that obtained with the other markers. Therefore, acid-insoluble ash was preferred as a dietary marker. Using the above protocol, protein and amino acid digestibility of some animal and plant protein ingredients were evaluated in a series of experiments. The first trial compared the apparent digestibility coefficients of some animal products included as single protein source in the test diets. Apparent protein digestibility values were 84.5 %, 83.8 %, 85.8 % and 83.1 % for fishmeal-prime, fishmeal-standard, poultry meal and pork meal, respectively. Apparent digestibility coefficients for poultry meal were comparable to those of fishmeal, which indicate its potential as a substitute for fishmeal in the diets of A. japonicus. The second trial determined the apparent coefficients of plant and animal protein sources included at 30 % into a practical reference diet (70 %). Apparent protein digestibility ranged from 92.4 % in sunflower meal to 85.5 % in corn gluten meal. Soybean meal is a promising feed ingredient in A. japonicus due to the high apparent digestibility of its protein (92.0 %) and essential amino acid digestibility (mean average 91.4 %). A fundamental assumption in fish feed formulation is that the digestibility of nutrients is additive, i.e., digestibility of a nutrient in one ingredient does not interact with the digestibility of the same nutrient in another ingredient. In the third trial, additivity of feed ingredients was tested using pork meal and poultry meal. The results indicate that the apparent digestibility coefficient of animal protein ingredients could be calculated from compound diets to accurately determine protein and amino acid digestibility in A. japonicus, and possibly other carnivorous fish species. Dietary essential amino acid requirements were determined for juvenile A. japonicus in two trials. A dose-response study was conducted using crystalline lysine to determine the optimal requirement of dietary lysine for A. japonicus. Optimal dietary lysine was estimated at 31.7 g kg-¹ dry diet, corresponding to 73.5 g kg-¹ of dietary protein, based on specific growth rate and broken-line segmented regression analyses. Dietary requirements for other essential amino acids ranged from 22 g kg-¹ (histidine) to 71 g kg-¹ (leucine) crude protein. The results of the present study provided a research tool that could be used to assess and verify the conclusions of earlier dietary work on A. japonicus and in further studies to develop least cost diet formulations for this species. The study also adds to the knowledge of the nutritional requirements of A. japonicus by providing information on the digestibility of plants and animal protein ingredients. It also contributes to future dietary research for this species because this study determines, for the first time, the most suitable methods for investigating the digestibility of raw materials for A. japonicus.
- Full Text:
- Date Issued: 2017