List of Titles

Synthesis, structure and in vitro anti-trypanosomal activity of non-toxic Arylpyrrole-Based Chalcone derivatives:

- Zulu, Ayanda I, Oderinlo, Ogunyemi O, Kruger, Cuan, Isaacs, Michelle, Hoppe, Heinrich C, Smith, Vincent J, Veale, Clinton G L, Khanye, Setshaba D

Authors: Zulu, Ayanda I , Oderinlo, Ogunyemi O , Kruger, Cuan , Isaacs, Michelle , Hoppe, Heinrich C , Smith, Vincent J , Veale, Clinton G L , Khanye, Setshaba D
Date: 2020
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/179017 , vital:40096 , https://doi.org/10.3390/molecules25071668
Description: With an intention of identifying chalcone derivatives exhibiting anti-protozoal activity, a cohort of relatively unexplored arylpyrrole-based chalcone derivatives were synthesized in moderate to good yields. The resultant compounds were evaluated in vitro for their potential activity against a cultured Trypanosoma brucei brucei 427 strain. Several compounds displayed mostly modest in vitro anti-trypanosomal activity with compounds 10e and 10h emerging as active candidates with IC50 values of 4.09 and 5.11 µM, respectively. More importantly, a concomitant assessment of their activity against a human cervix adenocarcinoma (HeLa) cell line revealed that these compounds are non-toxic.
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Date Issued: 2020

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Learning about volunteering: an exploration of literacy volunteers' experiences

- Yendall, Kaitlin Amy

Authors: Yendall, Kaitlin Amy
Date: 2020
Subjects: Literacy -- Study and teaching -- South Africa , Literacy programs -- South Africa , Voluntarism -- South Africa , Volunteer workers in community development -- Training of , Service learning , Language and education -- South Africa , Language arts (Primary) , English language -- Study and teaching (Elementary) , Volunteer workers in Education -- Training of
Language: English
Type: text , Thesis , Masters , MA
Identifier: http://hdl.handle.net/10962/138336 , vital:37623
Description: After almost 25 years of democracy in South Africa, not everyone has access to the same quality education. The responsibility of creating a literate society however cannot rely on the national government and schools alone, but instead needs to fall on the shoulders of various stakeholders. Volunteers in particular have an important role to play in remedying the current literacy crisis experienced in South Africa. This study takes the form of a case study approach and examines the experiences of Project Read literacy volunteers. A telephonic survey and two focus group discussions were conducted in order to determine who it is that volunteers for the programme; what prompts these particular individuals to volunteer; the perceived benefits of volunteering; and how volunteers report on their volunteering experiences. Although the Project Read programme is focused on the early literacy development of learners, volunteers seemed to undergo a developmental process themselves – something they had not anticipated at the start of their volunteering journey. This study illustrates the power of meaningful relationships in breaking down artificial categories and in bringing about important change with regards to the perceptions and attitudes of individuals towards community engagement. It is hoped that the data generated through this study will assist in recruiting and retaining more literacy volunteers through feedback to the NGO. In this way more children will be assisted to enhance their literacy competencies, from which they can build and achieve.
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Date Issued: 2020

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A holistic approach in understanding the effects of dietary protein sources on the growth and reproductive development of farmed abalone, Haliotis midae

- Wu, Yu

Authors: Wu, Yu
Date: 2020
Subjects: Abalones -- Nutrition , Abalones -- Reproduction , Abalones -- Growth , Abalone culture , Haliotis midae -- Nutrition , Haliotis midae -- Reproduction , Haliotis midae -- Growth , Haliotis midae fisheries
Language: English
Type: text , Thesis , Doctoral , PhD
Identifier: http://hdl.handle.net/10962/167719 , vital:41506
Description: The combination of fishmeal and soya in the formulated feed of farmed South African abalone, Haliotis midae, not only improved abalone growth, but also the sustainability of the compound diets by reducing the reliance on fishmeal. However, the presence of soya produced larger gonads compared to those of abalone fed kelp or single-source protein diets. There is an increasing drive to control sexual maturation and reduce undesirable spawning events in farmed abalone. However, the reasons for the reported effects of soya inclusion on the reproductive development of farmed H. midae remain unresolved. The aim of this research was to use a combination of techniques to contribute to the understanding of the relationship between growth, reproductive and nutritional physiology of farmed H. midae fed diets of varying protein sources. These techniques included stable isotope analysis (SIA), fatty acid analysis, gonad histological assessments and haemolymph sexsteroid hormone analysis. The objectives were to examine the allocation of protein and nutritional components to somatic and reproductive tissues. This study also included the first attempt to investigate the role that sex steroid hormones play during gametogenesis. Abalone (40 – 50 g abalone-1) were fed one of four diets: either a single-source protein-based diet, i.e., (1) fishmeal-only (FM) or (2) soya-only (S), or a combination diet of (3) fishmeal-soya (FM S) or (4) fishmeal-sunflower meal (FM SM). Sampling occurred in 45-day intervals over one year. Dietary protein source had an effect on the growth of abalone, with enhancements in growth linked to the combination of fishmeal and a plant-protein source. The fishmeal ingredient was the most utilised protein source throughout the temporal changes in protein allocation into somatic and reproductive tissue, followed by soya and then sunflower meal. The mean whole- body mass of abalone was significantly influenced by an interaction between time and dietary treatment, with average whole-body mass changing differently over time between treatments (RM-ANOVA, F(24, 96) = 2.13, p = 0.005). Overall, abalone that were fed FM S had higher mean whole-body mass values than abalone that were fed the single-protein based diets, while abalone that were fed FM SM were similar to animals from all dietary treatments (RMANOVA, F(3, 12) = 5.75, p = 0.01). Male abalone had significantly higher gonad bulk index (GBI) values compared to females (RM-ANOVA, F(1, 24) = 49.03, p < 0.001) and this was independent of dietary treatment. Within each sex, female abalone fed the FM S diet (15.92 ± 1.88 mm3 g-1) had significantly higher GBI values than abalone fed S (9.76 ± 1.08 mm3 g-1), while abalone fed FM (11.96 ± 1.71 mm3 g-1) and FM SM (11.90 ± 0.80 mm3 g-1) were similar to abalone from all other dietary treatments (Tukey’s HSD, p < 0.05). Male abalone fed the FM S (21.59 ± 2.10 mm3 g-1) and FM SM diet (19.30 ± 2.63 mm3 g-1) had similar GBI values and they were significantly higher than in abalone fed the S diet (14.74 ± 1.27 mm3 g-1), while abalone fed FM S had significantly higher GBI values than abalone that consumed the FM diet (15.08 ±1.63mm3 g-1) ( Tukey’s HSD, p < 0.05). Although sunflower meal was poorly utilised, it produced similar overall growth to abalone that were fed the FM S diets. Yet, feed conversion ratio values were significantly lower for abalone fed FM S (1.30 ± 0.13) compared to those in the other three treatments, with ratios ranging from 1.65 – 1.72 over the one-year. The fatty acid compositions of the somatic and gonadal tissues were similar between treatments (PERMANOVA, p = 0.21), while fatty acid composition was influenced by sampling day, tissue type and abalone sex (PERMANOVA, p < 0.05). The essential fatty acids (EFAs) eicosadienoic acid and a-linolenic acid were present in abalone tissue, but they were not detected in the diets, suggesting the important role that an alternate food source (e.g. farmed abalone also had access to diatoms) may have played and the ability that H. midae may have in converting long-chain polyunsaturated fatty acids from C18 precursors. A change in the abundance of EFAs in the gonad tissue during highest and lowest GBI values suggested that arachidonic, eicosapentaenoic, g-linolenic and linoleic acid were important in females, while eicosapentaenoic, eicosadienoic and a-linolenic acid were important for male reproductive development. Dietary protein sources had an effect on the frequency distribution of maturity stages, where females that were fed FM S produced more ripe gonads and more males that were fed FM SM contained testes that showed signs of ripeness over the one-year study. Although dietary protein influenced the sex steroid concentrations in females and males, exhibiting fluctuations throughout the one-year period, no distinct pattern linked to gametogenesis were observed. The results from this study illustrate: (1) the importance of conducting laboratory studies when implementing SIA and mixing models in aquaculture nutrition; (2) conducting nutritional studies on mature, grow-out abalone; and (3) assessing the importance of naturally occurring diatoms in their diet and their contribution to growth and reproduction. The novel contribution of this research towards abalone nutritional physiology, the implications of these findings to industry as well as potential considerations for future studies were addressed.
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Date Issued: 2020

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Poor whites and the post-apartheid labour market: a study of perceptions and experiences of work among residents in a homeless shelter in Johannesburg

- Wollnik, Nadjeschda

Authors: Wollnik, Nadjeschda
Date: 2020
Subjects: Poor whites -- South Africa , Poor whites -- South Africa -- Atitudes , Shelters for the homeless -- South Africa , Unemployed -- South Africa -- Attitudes , Unemployed -- South Africa , South Africa -- Social conditions -- 1994- , South Africa -- Economic conditions -- 1991-
Language: English
Type: text , Thesis , Masters , MSocSci
Identifier: http://hdl.handle.net/10962/148540 , vital:38748
Description: Despite historical precedents, poverty among white people in South Africa remains an anomaly and a paradox. Likewise, the perceptions of work and employment among poor (under- and unemployed) whites in contemporary South Africa have received scant attention in the scholarly literature. Using the conceptual frameworks of critical whiteness studies and segmented labour market theory – as a way of combining subjective and objective considerations – this research seeks to describe and explain the perceptions and experiences of the labour market among poor whites living in a homeless shelter in Johannesburg. Eight respondents were chosen for extended, in-depth interviews in an effort to develop a fine-grained understanding of the pre-existing circumstances that affected their access to information and thus shaped their choices in the labour market, as well as to ascertain what they believed to be the barriers that they face in the labour market. The findings varied, with most of the interviewees seeing ‘being white’ as the reason for their poverty and unemployment, while others exhibited some awareness of the role of their lack of skills and qualifications in their capacity to compete in higher segments of the labour market. The findings were also varied in the sense that not all interviewees experienced poverty in the same manner, with some having been part of the middle class prior to becoming poor, while others having been poor their entire lives. It was also found that class or socio-economic status seemed to have a greater impact than race on the labour market prospects of the interviewees. It is argued that the perceptions of these poor whites, which are informed by their lack of information about the workings of the labour market, rather than their lack of qualifications or their race, most affected their prospects in the labour market. The mechanisms they rely on when seeking employment reveal a poor knowledge of the local labour market and the ways in which they think their skillsets match up to the types of jobs they desire. The lack of understanding of the South African labour market and the policies that are in place to redress the legacies of apartheid are among the factors influencing the lack of success these poor whites are experiencing in their search for work.
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Date Issued: 2020

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A comparative study of the effect of different stabilizers on the critical quality attributes of self-assembling nano co-crystals

- Witika, Bwalya A, Smith, Vincent J, Walker, Roderick B

Authors: Witika, Bwalya A , Smith, Vincent J , Walker, Roderick B
Date: 2020
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/183224 , vital:43931 , xlink:href=" https://doi.org/10.3390/pharmaceutics12020182"
Description: Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used orally to manage HIV/AIDS infection. A pseudo one-solvent bottom-up approach was used to develop and produce nano co-crystals of 3TC and AZT. Equimolar amounts of 3TC dissolved in de-ionized water and AZT in methanol were rapidly injected into a pre-cooled vessel and sonicated at 4 °C. The resultant suspensions were characterized using a Zetasizer. The particle size, polydispersity index and Zeta potential were elucidated. Further characterization was undertaken using powder X-ray diffraction, Raman spectroscopy, Fourier transform infrared spectroscopy, differential scanning calorimetry, and energy dispersive X-ray spectroscopy scanning electron microscopy. Different surfactants were assessed for their ability to stabilize the nano co-crystals and for their ability to produce nano co-crystals with specific and desirable critical quality attributes (CQA) including particle size (PS) less than 1000 nm, polydispersity index (PDI) less than 0.500 and Zeta potential (ZP) less than −30 mV. All surfactants produced co-crystals in the nanometer range. The PDI and PS are concentration-dependent for all nano co-crystals manufactured while only ZP was within specification when sodium dodecyl sulfate was used in the process.
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Date Issued: 2020

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Biocompatibility of biomaterials for nanoencapsulation: Current approaches

- Witika, Bwalya A, Makoni, Pedzisai A, Matafwali, Scott K, Chabalenge, Billy, Mwila, Chiluba, Kalungia, Aubrey C, Nkanga, Christian I, Bapolisi, Alain M, Walker, Roderick B

Authors: Witika, Bwalya A , Makoni, Pedzisai A , Matafwali, Scott K , Chabalenge, Billy , Mwila, Chiluba , Kalungia, Aubrey C , Nkanga, Christian I , Bapolisi, Alain M , Walker, Roderick B
Date: 2020
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/183289 , vital:43939 , xlink:href="https://doi.org/10.3390/nano10091649"
Description: Nanoencapsulation is an approach to circumvent shortcomings such as reduced bioavailability, undesirable side effects, frequent dosing and unpleasant organoleptic properties of conventional drug delivery systems. The process of nanoencapsulation involves the use of biomaterials such as surfactants and/or polymers, often in combination with charge inducers and/or ligands for targeting. The biomaterials selected for nanoencapsulation processes must be as biocompatible as possible. The type(s) of biomaterials used for different nanoencapsulation approaches are highlighted and their use and applicability with regard to haemo- and, histocompatibility, cytotoxicity, genotoxicity and carcinogenesis are discussed.
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Date Issued: 2020

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Quality by Design Optimization of Cold Sonochemical Synthesis of Zidovudine-Lamivudine Nanosuspensions:

- Witika, Bwalya A, Smith, Vincent J, Walker, Roderick B

Authors: Witika, Bwalya A , Smith, Vincent J , Walker, Roderick B
Date: 2020
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/148424 , vital:38738 , https://doi.org/10.3390/pharmaceutics12040367
Description: Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used to manage HIV/AIDS infection. The compounds require frequent dosing, exhibit unpredictable bioavailability and a side effect profile that includes hepato- and haema-toxicity. A novel pseudo one-solvent bottom-up approach and Design of Experiments using sodium dodecyl sulphate (SDS) and α-tocopheryl polyethylene glycol succinate 1000 (TPGS 1000) to electrosterically stablize the nano co-crystals was used to develop, produce and optimize 3TC and AZT nano co-crystals. Equimolar solutions of 3TC in surfactant dissolved in de-ionised water and AZT in methanol were rapidly injected into a vessel and sonicated at 4 °C.
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Date Issued: 2020

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Nano-biomimetic drug delivery vehicles: Potential approaches for COVID-19 treatment

- Witika, Bwalya A, Makoni, Pedzisai A, Mweetwa, Larry L, Ntemi, Pascal V, Chikukwa, Mellisa T R, Matafwali, Scott K, Mwila, Chiluba, Mudenda, Steward, Katandula, Jonathan, Walker, Roderick B

Authors: Witika, Bwalya A , Makoni, Pedzisai A , Mweetwa, Larry L , Ntemi, Pascal V , Chikukwa, Mellisa T R , Matafwali, Scott K , Mwila, Chiluba , Mudenda, Steward , Katandula, Jonathan , Walker, Roderick B
Date: 2020
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/183440 , vital:43991 , xlink:href="https://doi.org/10.3390/molecules25245952"
Description: The current COVID-19 pandemic has tested the resolve of the global community with more than 35 million infections worldwide and numbers increasing with no cure or vaccine available to date. Nanomedicines have an advantage of providing enhanced permeability and retention and have been extensively studied as targeted drug delivery strategies for the treatment of different disease. The role of monocytes, erythrocytes, thrombocytes, and macrophages in diseases, including infectious and inflammatory diseases, cancer, and atherosclerosis, are better understood and have resulted in improved strategies for targeting and in some instances mimicking these cell types to improve therapeutic outcomes. Consequently, these primary cell types can be exploited for the purposes of serving as a "Trojan horse" for targeted delivery to identified organs and sites of inflammation. State of the art and potential utilization of nanocarriers such as nanospheres/nanocapsules, nanocrystals, liposomes, solid lipid nanoparticles/nano-structured lipid carriers, dendrimers, and nanosponges for biomimicry and/or targeted delivery of bioactives to cells are reported herein and their potential use in the treatment of COVID-19 infections discussed. Physicochemical properties, viz., hydrophilicity, particle shape, surface charge, composition, concentration, the use of different target-specific ligands on the surface of carriers, and the impact on carrier efficacy and specificity are also discussed.
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Date Issued: 2020

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Electricity use behaviour in a high-income neighbourhood in Johannesburg, South Africa:

- Williams, Stephanie P, Thondhlana, Gladman, Kua, Harn W

Authors: Williams, Stephanie P , Thondhlana, Gladman , Kua, Harn W
Date: 2020
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/149725 , vital:38878 , https://doi.org/10.3390/su12114571
Description: Worldwide, households’ consumption of electricity contributes to a substantial proportion of total national energy demand. Thus, the residential sector is a major entity in efforts to define and achieve global sustainability goals. Understanding electricity use behaviour and factors underlying behaviour is critical for designing behaviour change interventions, particularly in contexts characterised by fast-growing economies, burgeoning number of high-income households, and consumption growth. However, relative to developed economies, very little is known on this subject in South Africa. Using structured questionnaires, this study examines electricity use behaviour among high-income households in Johannesburg, South Africa.
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Date Issued: 2020

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Critical success factors in implementing projects on restituted land parcels in South Africa

- Whiting, Christoper Whiting

Authors: Whiting, Christoper Whiting
Date: 2020
Subjects: Community development -- Management -- South Africa , Community development -- Management -- South Africa -- Case studies , Economic development projects -- Management -- South Africa , Economic development projects -- Management -- South Africa -- Case studies , Land reform -- South Africa -- Economic aspects , Land reform beneficiaries -- South Africa -- Case studies , Restitution -- South Africa -- Case studies
Language: English
Type: text , Thesis , Masters , MBA
Identifier: http://hdl.handle.net/10962/167697 , vital:41504
Description: Currently there is a perception in South Africa that projects undertaken on parcels of restituted land are experiencing a much higher failure than success rate. There are, however, a few projects that are reaping the rewards and uplifting their communities, as intended by the land redistribution program. One community in particular, located in Mpumalanga, called community A, is presently undertaking a development project. This development project is one of the most successful restituted land parcel projects ever in South Africa. The purpose of the study is to determine the critical success factors in this community development project that have allowed it to enjoy such high levels of success. Are these critical success factors different from the generic industry critical success factors and, if so, what are they? As informed through literature, the critical success factors focused on in this study are as follows: the influence of management, project communication, knowledge management, the role of senior management, business strategy, project success measurements, and training and development. For the empirical study, a physical questionnaire was handed to 35 management members currently employed in the community development project. The questionnaire requested the demographics of all participants and asked them to rate, using a five-point Likert scale, their perceptions of the present project activities and of the importance of the project activities mentioned in making the project successful. Participants had to indicate the extent to which they agreed with each statement in the questionnaire. The responses obtained from the survey were presented and analysed. The study found that the critical success factor “role of senior management” was the largest problem area in the restituted land development project. “Training and development opportunities” came in second, with both factor areas showing large variances. Recommendations have been given on how to address both these problematic areas in the development project and how future restituted land parcel projects can better utilize these factors to ensure successful project implementation and long-term project success.
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Date Issued: 2020

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Relevant knowledge: content analysis of research conducted by South African psychology masters students (2008-2012

- Whitehead, Tracey

Authors: Whitehead, Tracey
Date: 2020
Subjects: Psychology -- Research -- South Africa , Psychology -- Study and teaching (Higher) -- South Africa , Psychology students -- South Africa
Language: English
Type: text , Thesis , Masters , MA
Identifier: http://hdl.handle.net/10962/167683 , vital:41503
Description: In South Africa, Psychology has had a chequered past mainly due to its role in the justification of apartheid policies. Due to apartheid's socio-economic injustices, confidence in the applicability of psychological knowledge to South Africa's social problems was insufficient. Psychologists attempted to raise consciousness of the social relevance of psychology by contributing relevant knowledge and being reactive to social inequalities and related psychosocial issues affecting South Africa. This study aimed to conduct a content analysis of trends in research produced by Psychology Masters' students in the fields of Clinical, Counselling and Research psychology over a period of 5 years (2008-2012). The corpus of data was then compared with the key issues raised in the United Nations Development Programme's South Africa human development report (2003), along with a focus on articles published by Macleod (2004) and Macleod and Howell (2013). It emerged that Empirical Qualitative studies, based on post-modern frameworks, as well as HIV/AIDS, Knowledge Production, Assessment and Measurement and Programme development and evaluation, dominated psychological research. Participants were mainly urban, middle class adults living in the 3 wealthiest provinces. University students were the most popular participant group. While it is encouraging that students were attempting to engage with psychosocial issues, the limited number of key social issues addressed, the under-representation of certain sectors of the South African population, as well as the impact of socioeconomic status on well-being requires greater attention at Masters' level to ensure Psychology's psychosocial relevance.
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Date Issued: 2020

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Use of a non-hepatic cell line highlights limitations associated with cell-based assessment of metabolically induced toxicity:

- Weyers, Carli, Dingle, Laura M K, Wilhelmi, Brendan S, Edkins, Adrienne L, Veale, Clinton G

Authors: Weyers, Carli , Dingle, Laura M K , Wilhelmi, Brendan S , Edkins, Adrienne L , Veale, Clinton G
Date: 2020
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/160290 , vital:40431 , DOI: 10.1080/01480545.2019.1585869
Description: Metabolically induced drug-toxicity is a major cause of drug failure late in drug optimization phases. Accordingly, in vitro metabolic profiling of compounds is being introduced at earlier stages of the drug discovery pipeline. An increasingly common method to obtain these profiles is through overexpression of key CYP450 metabolic enzymes in immortalized liver cells, to generate competent hepatocyte surrogates. Enhanced cytotoxicity is presumed to be due to toxic metabolite production via the overexpressed enzyme. However, metabolically induced toxicity is a complex multi-parameter phenomenon and the potential background contribution to metabolism arising from the use of liver cells which endogenously express CYP450 isoforms is consistently overlooked. In this study, we sought to reduce the potential background interference by applying this methodology in kidney-derived HEK293 cells which lack endogenous CYP450 expression.
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Date Issued: 2020

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Does the construction of ‘rapeable’ bodies constitute an instance of hermeneutical injustice?

- Weiffenbach, Michaela

Authors: Weiffenbach, Michaela
Date: 2020
Subjects: Zuma, Jacob -- Trials, litigation, etc. , Rape -- Philosophy , Women's rights -- Africa , Women, Black -- Social conditions -- Africa , Masculinity -- Africa , Men, Black -- Africa -- Psychology , Justice (Philosophy)
Language: English
Type: text , Thesis , Masters , MA
Identifier: http://hdl.handle.net/10962/145708 , vital:38460
Description: This thesis argues that within the conventional imagination of the West, identity functions in a way that particular forms of embodiment are characterised by the experience of endured sexual vulnerability, which I argue is best understood as the construction of ‘rapeable’ bodies (Cahill 2001, 120). By this, I mean that the threat of rape is contingent upon the social and political construction of one’s identity as vulnerable. In virtue of this particular way of constructing the embodiment of certain subjectivities, there is an instance of hermeneutical injustice conferred (Fricker 2007, 114). I inquire into the function and meaning of stereotypic generalisations, prejudice and rape myths embedded within the dominant framework of the West and show how language and representation constructs these identities as ‘rapeable’. Furthermore, I consider how collective hermeneutical discourses construct Blackness, specifically Black masculinities and the construction of the ‘un-rapeable’ Black femxle body. To see how these ideas are congruous the prominent example that occurred in South Africa in 2005, namely, the Jacob Zuma rape trial comes to mind. One relevant feature of the case is that it shows how identities of race are constructed in the aftermath of apartheid and points to a Western collective imagination resistant to change. In addition, it demonstrates the triad of interrelatedness holding between the self-world-other, a relationship constituted mutually by the self and the socially constructed interpretations of identity and embodiment (du Toit 2009, 58). Lastly, the construction of ‘rapeable’ bodies is an example of how discursive narratives construct particular identities as vulnerable through rendering particular embodied subjects as sexually irrelevant and hermeneutically obscured.
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Date Issued: 2020

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Bat species richness and community composition along a mega-transect in the Okavango river basin:

- Weier, Sina M, Keith, Mark, Neef, Götz G, Parker, Daniel M, Taylor, Peter

Authors: Weier, Sina M , Keith, Mark , Neef, Götz G , Parker, Daniel M , Taylor, Peter
Date: 2020
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/149264 , vital:38820 , https://doi.org/10.3390/d12050188
Description: The Okavango River Basin is a hotspot of bat diversity that requires urgent and adequate protection. To advise future conservation strategies, we investigated the relative importance of a range of potential environmental drivers of bat species richness and functional community composition in the Okavango River Basin. During annual canoe transects along the major rivers, originating in the central Angolan highlands, we recorded more than 25,000 bat echolocation calls from 2015 to 2018. We corrected for possible biases in sampling design and effort.
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Date Issued: 2020

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Mapping subtidal estuarine habitats with a remotely operated underwater vehicle (ROV):

- Wasserman, J, Claassens, L, Adams, J B

Authors: Wasserman, J , Claassens, L , Adams, J B
Date: 2020
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/150163 , vital:38945 , DOI: 10.2989/1814232X.2020.1731598
Description: Subtidal habitats have not yet been accounted for in habitat maps of South African estuaries. In this study, a novel method for mapping subtidal estuarine habitats, using a remotely operated underwater vehicle (ROV) piloted from a boat, was developed and tested in the Knysna Estuary. Video footage was recorded along 48 transects across the width of the estuary, and then reviewed to identify, classify and map habitats. Using the method developed in this study, 21 hours of footage was recorded over 15 days of sampling, and about 30 hours of post-processing was carried out to map an area exceeding 850 ha. This study has produced the first baseline dataset of subtidal habitats for a South African estuary. Additionally, the study revealed the previously unknown distribution of the invasive red seaweed Asparagopsis taxiformis, and the underestimation in previous studies of the estuary of area cover of eelgrass Zostera capensis by 130 ha.
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Date Issued: 2020

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Perceived benefits of nature-based experiences as mediators of connectedness with nature: The case of Mystic Mountain

- Ward-Smith, Chesney, Naidoo, Tony, Olvitt, Lausanne L, Olvitt, Lausanne, Akhurst, Jacqueline

Authors: Ward-Smith, Chesney , Naidoo, Tony , Olvitt, Lausanne L , Olvitt, Lausanne , Akhurst, Jacqueline
Date: 2020
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/372782 , vital:66622 , xlink:href="https://doi.org/10.1177/00812463209470"
Description: Perceived nature disconnection lies at the heart of the world’s socio-ecological crisis. Finding ways to reconnect with nature is fundamental towards reducing the adverse psychological–social– ecological consequences of this disconnection. Understanding the psychological and social benefits of nature-based experiences is important towards actualising reconnection. This article discusses such benefits for child and adult participants from the Eastern Cape, South Africa. This work stems from Ecopsychology research with an outdoor education centre, Mystic Mountain. The experiences of two groups of children (n=25, aged 10–14years) and adult instructors (n=12, aged 18–50years) were explored using interpretive case-study methodology. Through semi-structured interviews and focus groups, participant observation, and reflexive journaling, data were collected and analysed thematically. This article centralises participants’ perceived psychological and social benefits of nature-based experiences as mediators of deeper self and nature connectedness. Integrating these benefits into nature-based pedagogy-design processes could contribute towards more effective enhancements of nature connectedness, and in turn, foster Earth’s larger flourishment.
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Date Issued: 2020

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UN Decade on Ecosystem Restoration 2021–2030: what chance for success in restoring coastal ecosystems?

- Waltham, Nathan J, Elliott, Michael, Lee, Shing Yip, Lovelock, Catherine, Duarte, Carlos M, Buelow, Christina, Simenstad, Charles, Nagelkerken, Ivan, Claassens, Louw, Wen, Colin K-C, Barletta, Mario, Connolly, Rod M, Gillies, Chris, Mitsch, William J, Ogburn, Matthew B, Purandare, Jemma, Possingham, Hugh, Sheaves, Marcus

Authors: Waltham, Nathan J , Elliott, Michael , Lee, Shing Yip , Lovelock, Catherine , Duarte, Carlos M , Buelow, Christina , Simenstad, Charles , Nagelkerken, Ivan , Claassens, Louw , Wen, Colin K-C , Barletta, Mario , Connolly, Rod M , Gillies, Chris , Mitsch, William J , Ogburn, Matthew B , Purandare, Jemma , Possingham, Hugh , Sheaves, Marcus
Date: 2020
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/149836 , vital:38887 , https://doi.org/10.3389/fmars.2020.00071
Description: On 1 March 2019, the United Nations (UN) General Assembly (New York) declared 2021–2030 the “UN Decade on Ecosystem Restoration.” This call to action has the purpose of recognizing the need to massively accelerate global restoration of degraded ecosystems, to fight the climate heating crisis, enhance food security, provide clean water and protect biodiversity on the planet. The scale of restoration will be key; for example, the Bonn Challenge has the goal to restore 350 million km2 (almost the size of India) of degraded terrestrial ecosystems by 2030. However, international support for restoration of “blue” coastal ecosystems, which provide an impressive array of benefits to people, has lagged. Only the Global Mangrove Alliance (https://mangrovealliance.org/) comes close to the Bonn Challenge, with the aim of increasing the global area of mangroves by 20% by 2030. However, mangrove scientists have reservations about this target, voicing concerns that it is unrealistic and may prompt inappropriate practices in attempting to reach this target (Lee et al., 2019). The decade of ecosystem restoration declaration also coincides with the UN Decade of Ocean Science for Sustainable Development, which aims to reverse deterioration in ocean health. If executed in a holistic and coordinated manner, signatory nations could stand to deliver on both these UN calls to action.
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Date Issued: 2020

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Antiparasitic Constituents of Beilschmiedia louisii and Beilschmiedia obscura and Some Semisynthetic Derivatives

- Waleguele, Christine C, Mba'ning, Brice M, Awantu, Angelbert F, Bankeu, Jean J, Fongang, Yannick S F, Ngouela, Augustin S, Tsamo, Etienne, Sewald, Norbert, Lenta, Bruno N, Krause, Rui W M

Authors: Waleguele, Christine C , Mba'ning, Brice M , Awantu, Angelbert F , Bankeu, Jean J , Fongang, Yannick S F , Ngouela, Augustin S , Tsamo, Etienne , Sewald, Norbert , Lenta, Bruno N , Krause, Rui W M
Date: 2020
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/193364 , vital:45325 , xlink:href="https://doi.org/10.3390/molecules25122862"
Description: The MeOH/CH2Cl2 (1:1) extracts of the roots and leaves of Beilschmiedia louisii and B. obscura showed potent antitrypanosomal activity during preliminary screening on Trypanosoma brucei brucei. Phytochemical investigation of these extracts led to the isolation of a mixture of two new endiandric acid derivatives beilschmiedol B (1) and beilschmiedol C (2), and one new phenylalkene obscurene A (3) together with twelve known compounds (4–15). In addition, four new derivatives (11a–11d) were synthesized from compound 11. Their structures were elucidated based on their NMR and MS data. Compounds 5, 6, and 7 were isolated for the first time from the Beilschmiedia genus. Additionally, the NMR data of compound 4 are given here for the first time. The isolates were evaluated for their antitrypanosomal and antimalarial activities against Tb brucei and the Plasmodium falciparum chloroquine-resistant strain Pf3D7 in vitro, respectively. From the tested compounds, the mixture of new compounds 1 and 2 exhibited the most potent antitrypanosomal activity in vitro with IC50 value of 4.91 μM.
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Date Issued: 2020

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