Melatonin alters the photodegradation of paracetamol
- Anoopkumar-Dukie, Shailendra, Glass, Beverley D, Walker, Roderick B, Daya, Santylal
- Authors: Anoopkumar-Dukie, Shailendra , Glass, Beverley D , Walker, Roderick B , Daya, Santylal
- Date: 2000
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184357 , vital:44211 , xlink:href="https://doi.org/10.1211/146080800128735755"
- Description: The effects of melatonin, a known free-radical scavenger, on paracetamol in the presence of UV irradiation was studied by use of HPLC. The experiments were performed in air and nitrogen. The results show that the rate of photodegradation of melatonin is faster in air than in nitrogen whereas that of paracetamol is similar in air and nitrogen. When the two drugs were combined, melatonin retarded the degradation of paracetamol for up to 6h in the presence of nitrogen. However, in the presence of air melatonin rapidly enhances the photodegradation of paracetamol. This study shows that a combination of melatonin and paracetamol in the presence of air and UV irradiation can lead to rapid inactivation of both agents, thus raising important concerns about the possible use of melatonin as sunscreen
- Full Text:
- Date Issued: 2000
- Authors: Anoopkumar-Dukie, Shailendra , Glass, Beverley D , Walker, Roderick B , Daya, Santylal
- Date: 2000
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184357 , vital:44211 , xlink:href="https://doi.org/10.1211/146080800128735755"
- Description: The effects of melatonin, a known free-radical scavenger, on paracetamol in the presence of UV irradiation was studied by use of HPLC. The experiments were performed in air and nitrogen. The results show that the rate of photodegradation of melatonin is faster in air than in nitrogen whereas that of paracetamol is similar in air and nitrogen. When the two drugs were combined, melatonin retarded the degradation of paracetamol for up to 6h in the presence of nitrogen. However, in the presence of air melatonin rapidly enhances the photodegradation of paracetamol. This study shows that a combination of melatonin and paracetamol in the presence of air and UV irradiation can lead to rapid inactivation of both agents, thus raising important concerns about the possible use of melatonin as sunscreen
- Full Text:
- Date Issued: 2000
Stability of prochlorperazine in solution and in the solid-state
- Authors: Antunes, Edith Martins
- Date: 2000
- Subjects: Phenothiazine
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4536 , http://hdl.handle.net/10962/d1016399
- Description: Prochlorperazine, a member of the piperazine subclass of phenothiazines, widely used as an anti-emetic, is susceptible to oxidation to sulfoxides. These are main metabolites and degradants of all phenothiazines which are found to be inactive at the dopamine receptors. Prochlorperazine causes photosensitivity effects in patients attributed to dechlorination at C2 with the release of HCI (Huang and Sands, 1967; Nejmeh and Pilpel, 1978; Moore and Tamat, 1980). The aim of this study is to investigate the thermal and photostability of prochlorperazine edisylate and mesylate salts in the solid state and in solution. Prochlorperazine is available as a fine chemical and in a variety of dosage forms, including injectables and tablets. According to ICH guidelines, any degradants greater than 0.1 % are required to be isolated and identified. In order to assess the photostability of the two salts, an HPLC method was developed and validated for linearity, accuracy and precision, selectivity, limit of detection, quantitation and ruggedness. Sulfoxides were synthesised for use as standards in the rate studies according to the well-known hydrogen peroxide method (Owens et al., 1989). The rate of prochlorperazine degradation in solution under various light sources (254 nm UV light, diffuse light and sunlight) was studied. The light sources used abovF were quantified using potassium ferrioxalate as a chemical actinometer). The photodegradation rate was found to be greater in ampoules sealed under nitrogen than air, but the thermal degradation was faster in ampoules sealed with air than those purged with nitrogen. Amber ampoules retarded the rate of degradation under all photolytic conditions. This is a vital consideration for the packaging and storage of prochlorperazine in injectables. Degradation was found to occur mainly by first-order kinetics and the degradation rate decreased in the following order: sunlight » UV light 254 nm > fluorescent I diffuse light. Solid state samples, however, were found to be relatively stable to the various light / heat conditions over a 6 month period when compared to prochlorperazine solutions, but still considerably unstable. Thus both storage and packaging is a vital consideration for prochlorperazine injectables. The thermal behaviour of mixtures of prochlorperazine with standard excipients, was assessed for potential interactions, using differential scanning calorimetry. For most of the excipients (magnesium stearate, stearic acid, Explotab®, AC-Di-Sol®, Encompress® and Ludipress®, lactose and Starch 1500®) disappearance or broadening of the melting endotherm of the drug indicated interactions. Lubritab®, however, was the only 'inert' excipient tested. Liquid chromatography - mass spectrometry (LC-MS) was used to determine the nature of the degradation products. The major degradation pathways included dechlorination and demethylation of the parent drug, as well as sulfoxidation and Noxidation. Prochlorperazine underwent dechlorination and sulfoxidation with subsequent photosubstitution to yield the 2-hydroxy derivative. The solid state photostudies showed the formation of dealkylated, oxidised and hydroxylated products, sulfoxides and dimers. Since N-demethylation, N-oxidation, sulfoxidation and aromatic hydroxylation are reported to occur in the in vitro metabolism of perazine derivatives, it does appear that there is some relationship between metabolites and photoproducts (Breyer, 1974). This study has been successful in providing understanding of the photolytic and thermal degradation pathways of prochlorperazine.
- Full Text:
- Date Issued: 2000
- Authors: Antunes, Edith Martins
- Date: 2000
- Subjects: Phenothiazine
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4536 , http://hdl.handle.net/10962/d1016399
- Description: Prochlorperazine, a member of the piperazine subclass of phenothiazines, widely used as an anti-emetic, is susceptible to oxidation to sulfoxides. These are main metabolites and degradants of all phenothiazines which are found to be inactive at the dopamine receptors. Prochlorperazine causes photosensitivity effects in patients attributed to dechlorination at C2 with the release of HCI (Huang and Sands, 1967; Nejmeh and Pilpel, 1978; Moore and Tamat, 1980). The aim of this study is to investigate the thermal and photostability of prochlorperazine edisylate and mesylate salts in the solid state and in solution. Prochlorperazine is available as a fine chemical and in a variety of dosage forms, including injectables and tablets. According to ICH guidelines, any degradants greater than 0.1 % are required to be isolated and identified. In order to assess the photostability of the two salts, an HPLC method was developed and validated for linearity, accuracy and precision, selectivity, limit of detection, quantitation and ruggedness. Sulfoxides were synthesised for use as standards in the rate studies according to the well-known hydrogen peroxide method (Owens et al., 1989). The rate of prochlorperazine degradation in solution under various light sources (254 nm UV light, diffuse light and sunlight) was studied. The light sources used abovF were quantified using potassium ferrioxalate as a chemical actinometer). The photodegradation rate was found to be greater in ampoules sealed under nitrogen than air, but the thermal degradation was faster in ampoules sealed with air than those purged with nitrogen. Amber ampoules retarded the rate of degradation under all photolytic conditions. This is a vital consideration for the packaging and storage of prochlorperazine in injectables. Degradation was found to occur mainly by first-order kinetics and the degradation rate decreased in the following order: sunlight » UV light 254 nm > fluorescent I diffuse light. Solid state samples, however, were found to be relatively stable to the various light / heat conditions over a 6 month period when compared to prochlorperazine solutions, but still considerably unstable. Thus both storage and packaging is a vital consideration for prochlorperazine injectables. The thermal behaviour of mixtures of prochlorperazine with standard excipients, was assessed for potential interactions, using differential scanning calorimetry. For most of the excipients (magnesium stearate, stearic acid, Explotab®, AC-Di-Sol®, Encompress® and Ludipress®, lactose and Starch 1500®) disappearance or broadening of the melting endotherm of the drug indicated interactions. Lubritab®, however, was the only 'inert' excipient tested. Liquid chromatography - mass spectrometry (LC-MS) was used to determine the nature of the degradation products. The major degradation pathways included dechlorination and demethylation of the parent drug, as well as sulfoxidation and Noxidation. Prochlorperazine underwent dechlorination and sulfoxidation with subsequent photosubstitution to yield the 2-hydroxy derivative. The solid state photostudies showed the formation of dealkylated, oxidised and hydroxylated products, sulfoxides and dimers. Since N-demethylation, N-oxidation, sulfoxidation and aromatic hydroxylation are reported to occur in the in vitro metabolism of perazine derivatives, it does appear that there is some relationship between metabolites and photoproducts (Breyer, 1974). This study has been successful in providing understanding of the photolytic and thermal degradation pathways of prochlorperazine.
- Full Text:
- Date Issued: 2000
Marie Sala
- Badou Boy (lead vocal, accoustic guitar, harmonica), Assane Thiam (Tama talking drum), Tapha Faye (piano), Mbaye Dieye Feye (Sabar and Percussions), Pathe Diassy (bass guitar), Fallilou Niang (drums), Ibou Cisse (piano), Badou Boy and Pape Armand (composers), Straun Douglas
- Authors: Badou Boy (lead vocal, accoustic guitar, harmonica) , Assane Thiam (Tama talking drum) , Tapha Faye (piano) , Mbaye Dieye Feye (Sabar and Percussions) , Pathe Diassy (bass guitar) , Fallilou Niang (drums) , Ibou Cisse (piano) , Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127304 , vital:35998 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-07
- Description: Singing accompanied by guitar and electric piano
- Full Text: false
- Date Issued: 2000
- Authors: Badou Boy (lead vocal, accoustic guitar, harmonica) , Assane Thiam (Tama talking drum) , Tapha Faye (piano) , Mbaye Dieye Feye (Sabar and Percussions) , Pathe Diassy (bass guitar) , Fallilou Niang (drums) , Ibou Cisse (piano) , Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127304 , vital:35998 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-07
- Description: Singing accompanied by guitar and electric piano
- Full Text: false
- Date Issued: 2000
Sentu Na
- Badou Boy (lead vocal, accoustic guitar, harmonica), Mbaye Dieye Feye (Sabar and Percussions), Badou Boy and Pape Armand (composers), Ndiaga Ndour, Ouzin NDoye
- Authors: Badou Boy (lead vocal, accoustic guitar, harmonica) , Mbaye Dieye Feye (Sabar and Percussions) , Badou Boy and Pape Armand (composers) , Ndiaga Ndour, Ouzin NDoye
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127313 , vital:35999 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-08
- Description: Singing accompanied by guitar and electric piano
- Full Text: false
- Date Issued: 2000
- Authors: Badou Boy (lead vocal, accoustic guitar, harmonica) , Mbaye Dieye Feye (Sabar and Percussions) , Badou Boy and Pape Armand (composers) , Ndiaga Ndour, Ouzin NDoye
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127313 , vital:35999 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-08
- Description: Singing accompanied by guitar and electric piano
- Full Text: false
- Date Issued: 2000
Missal Madjiguene
- Badou Boy and Pape Armand (composers), Straun Douglas
- Authors: Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127286 , vital:35996 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-05
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
- Authors: Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127286 , vital:35996 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-05
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
Music
- Badou Boy and Pape Armand (composers), Straun Douglas
- Authors: Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: English
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127277 , vital:35995 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-04
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
- Authors: Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: English
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127277 , vital:35995 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-04
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
Yama Daboon Ci Yoon
- Badou Boy and Pape Armand (composers), Badou Boy (lead vocal, accoustic guitar, harmonica, Pape Armand Boye (accousitc guitar, guitar solo, electric guitar, vocals), Mbaye Dieye Feye (Sabar and Percussions), Pathe Diassy (bass guitar), Straun Douglas
- Authors: Badou Boy and Pape Armand (composers) , Badou Boy (lead vocal, accoustic guitar, harmonica , Pape Armand Boye (accousitc guitar, guitar solo, electric guitar, vocals) , Mbaye Dieye Feye (Sabar and Percussions) , Pathe Diassy (bass guitar) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127295 , vital:35997 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-06
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
- Authors: Badou Boy and Pape Armand (composers) , Badou Boy (lead vocal, accoustic guitar, harmonica , Pape Armand Boye (accousitc guitar, guitar solo, electric guitar, vocals) , Mbaye Dieye Feye (Sabar and Percussions) , Pathe Diassy (bass guitar) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127295 , vital:35997 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-06
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
Les Vielles Cabanes Ensorcelees
- Badou Boy and Pape Armand (composers), Straun Douglas
- Authors: Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: French
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127268 , vital:35994 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-03
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
- Authors: Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: French
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127268 , vital:35994 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-03
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
Mboolo Mi
- Badou Boy and Pape Armand (composers), Straun Douglas
- Authors: Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127259 , vital:35993 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-02
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
- Authors: Badou Boy and Pape Armand (composers) , Straun Douglas
- Date: 2000
- Subjects: Popular music , Popular music--Senegal--2001-2010 , Africa Senegal Dakar f-sg
- Language: Wolof
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127259 , vital:35993 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO2-02
- Description: Singing accompanied by guitar and harmonica
- Full Text: false
- Date Issued: 2000
Kebali
- Banani Kone (composer, performer, arranger), Nalini, Mamani Keita, Bintou Camara (chorus), Dominique Sablier (piano), Raphael Chossin (drums), Julio (bass guitar), Mouriba Koita, Fousseni Kouyate (N'goni), Moussa Kone, Djelikedjan, Yacou (cora), Oumar Dagon, Moussa Kouyate, Partrick (guitars), Kerfala Kante (arranger), Eric Bono
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: English
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/${Handle} , vital:36029 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-06
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: English
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/${Handle} , vital:36029 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-06
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
Djeliya
- Banani Kone (composer, performer, arranger), Nalini, Mamani Keita, Bintou Camara (chorus), Dominique Sablier (piano), Raphael Chossin (drums), Julio (bass guitar), Mouriba Koita, Fousseni Kouyate (N'goni), Moussa Kone, Djelikedjan, Yacou (cora), Oumar Dagon, Moussa Kouyate, Partrick (guitars), Kerfala Kante (arranger), Eric Bono
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127595 , vital:36024 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-01
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127595 , vital:36024 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-01
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
Badoua Den
- Banani Kone (composer, performer, arranger), Nalini, Mamani Keita, Bintou Camara (chorus), Dominique Sablier (piano), Raphael Chossin (drums), Julio (bass guitar), Mouriba Koita, Fousseni Kouyate (N'goni), Moussa Kone, Djelikedjan, Yacou (cora), Oumar Dagon, Moussa Kouyate, Partrick (guitars), Kerfala Kante (arranger), Eric Bono
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127609 , vital:36026 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-03
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127609 , vital:36026 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-03
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
Tolo
- Banani Kone (composer, performer, arranger), Nalini, Mamani Keita, Bintou Camara (chorus), Dominique Sablier (piano), Raphael Chossin (drums), Julio (bass guitar), Mouriba Koita, Fousseni Kouyate (N'goni), Moussa Kone, Djelikedjan, Yacou (cora), Oumar Dagon, Moussa Kouyate, Partrick (guitars), Kerfala Kante (arranger), Eric Bono
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127604 , vital:36025 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-02
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127604 , vital:36025 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-02
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
Kounandi
- Banani Kone (composer, performer, arranger), Nalini, Mamani Keita, Bintou Camara (chorus), Dominique Sablier (piano), Raphael Chossin (drums), Julio (bass guitar), Mouriba Koita, Fousseni Kouyate (N'goni), Moussa Kone, Djelikedjan, Yacou (cora), Oumar Dagon, Moussa Kouyate, Partrick (guitars), Kerfala Kante (arranger), Eric Bono
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: English
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127631 , vital:36028 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-05
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: English
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127631 , vital:36028 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-05
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
Nianama
- Banani Kone (composer, performer, arranger), Nalini, Mamani Keita, Bintou Camara (chorus), Dominique Sablier (piano), Raphael Chossin (drums), Julio (bass guitar), Mouriba Koita, Fousseni Kouyate (N'goni), Moussa Kone, Djelikedjan, Yacou (cora), Oumar Dagon, Moussa Kouyate, Partrick (guitars), Kerfala Kante (arranger), Eric Bono
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127614 , vital:36027 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-04
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127614 , vital:36027 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-04
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
Wale Niouma
- Banani Kone (composer, performer, arranger), Nalini, Mamani Keita, Bintou Camara (chorus), Dominique Sablier (piano), Raphael Chossin (drums), Julio (bass guitar), Mouriba Koita, Fousseni Kouyate (N'goni), Moussa Kone, Djelikedjan, Yacou (cora), Oumar Dagon, Moussa Kouyate, Partrick (guitars), Kerfala Kante (arranger), Eric Bono
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127649 , vital:36030 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-07
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127649 , vital:36030 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-07
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
Nia o Nia
- Banani Kone (composer, performer, arranger), Nalini, Mamani Keita, Bintou Camara (chorus), Dominique Sablier (piano), Raphael Chossin (drums), Julio (bass guitar), Mouriba Koita, Fousseni Kouyate (N'goni), Moussa Kone, Djelikedjan, Yacou (cora), Oumar Dagon, Moussa Kouyate, Partrick (guitars), Kerfala Kante (arranger), Eric Bono
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127658 , vital:36031 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-08
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
- Authors: Banani Kone (composer, performer, arranger) , Nalini, Mamani Keita, Bintou Camara (chorus) , Dominique Sablier (piano) , Raphael Chossin (drums) , Julio (bass guitar) , Mouriba Koita, Fousseni Kouyate (N'goni) , Moussa Kone, Djelikedjan, Yacou (cora) , Oumar Dagon, Moussa Kouyate, Partrick (guitars) , Kerfala Kante (arranger) , Eric Bono
- Date: 2000
- Subjects: Popular music , Popular music--Mali--1991-2000 , Africa Mali Souther Region f-ml
- Language: Bambara
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/127658 , vital:36031 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDCO5-08
- Description: Malian modern band, solo female vocalist and chorus sing accompanied by N'goni, cora, guitar, piano and drums
- Full Text: false
- Date Issued: 2000
From virtual to physical reality with paper folding
- Authors: Bangay, Shaun D
- Date: 2000
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/432669 , vital:72891 , https://doi.org/10.1016/S0925-7721(99)00048-6
- Description: Objects in a virtual world can be converted into hardcopy by per-pendicular projection of each face onto a sheet of paper, cutting and gluing. Previously, use of this technique was restricted to a limited class of polyhedral objects. This paper extends this process to realis-tic virtual objects, with the traditional origami restriction of using only a single sheet of paper. A number of algorithms are explored to achieve this goal. The use of heuristics allows solutions to be found without exhaustive search of all possible layouts. Approaches to deal with pathological cases are described. The techniques have al-ready been successfully applied to a number of complex models, selected from a number of model archives on the Internet.
- Full Text:
- Date Issued: 2000
- Authors: Bangay, Shaun D
- Date: 2000
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/432669 , vital:72891 , https://doi.org/10.1016/S0925-7721(99)00048-6
- Description: Objects in a virtual world can be converted into hardcopy by per-pendicular projection of each face onto a sheet of paper, cutting and gluing. Previously, use of this technique was restricted to a limited class of polyhedral objects. This paper extends this process to realis-tic virtual objects, with the traditional origami restriction of using only a single sheet of paper. A number of algorithms are explored to achieve this goal. The use of heuristics allows solutions to be found without exhaustive search of all possible layouts. Approaches to deal with pathological cases are described. The techniques have al-ready been successfully applied to a number of complex models, selected from a number of model archives on the Internet.
- Full Text:
- Date Issued: 2000
The Raven's Coloured Progressive Matrices Test: a pilot study for the establishment of normative data for Xhosa-speaking primary school pupils in the Grahamstown region
- Authors: Bass, Natalie Tanyia
- Date: 2000
- Subjects: Raven's Progressive Matrices , Students -- South Africa -- Psychology , Educational tests and measurements -- South Africa , Intelligence levels -- South Africa , Students -- Psychology
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: vital:2930 , http://hdl.handle.net/10962/d1002439 , Raven's Progressive Matrices , Students -- South Africa -- Psychology , Educational tests and measurements -- South Africa , Intelligence levels -- South Africa , Students -- Psychology
- Description: The Raven’s Coloured Progressive Matrices (CPM) test is used extensively across a wide variety of settings in South Africa, however more appropriate local normative data has yet to be established. The CPM is internationally recognised as a culture-fair test of nonverbal intelligence, designed for use with children between the ages of 5½ and 11½. This pilot study thus sought to establish normative data for this instrument for a population of Xhosa-speaking Primary School children in the peri-urban township area in the Grahamstown region. The booklet version of the test was used and it was administered in group format and according to an alternate method of test administration (using Xhosa instructions) developed by Vass in 1992. The final normative sample consisted of 197 male and 182 female Xhosa-speaking children in Grades Two to Seven (N=379). The results showed (1) a significant effect of age on test scores, where scores increased with age as expected; (2) a consistent tendency for males to outperform females was also noted, however small sample sizes precluded any categorical claims to this effect; (3) no significant effect of education on test scores was observed and finally; (4) and finally, it appeared that the norms generated for this study revealed a tendency to be lower than those obtained by Raven, Court and Raven (1990) during the standardisation of this instrument in the United Kingdom and America. The study concluded that (1) there is an urgent need for more appropriate South African normative data for this test; and (2) that when assessing African children from disadvantaged backgrounds, further research into the effects of cultural and socio-economic factors and gender on non-verbal intelligence (and on performance on this test in particular) is required.
- Full Text:
- Date Issued: 2000
- Authors: Bass, Natalie Tanyia
- Date: 2000
- Subjects: Raven's Progressive Matrices , Students -- South Africa -- Psychology , Educational tests and measurements -- South Africa , Intelligence levels -- South Africa , Students -- Psychology
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: vital:2930 , http://hdl.handle.net/10962/d1002439 , Raven's Progressive Matrices , Students -- South Africa -- Psychology , Educational tests and measurements -- South Africa , Intelligence levels -- South Africa , Students -- Psychology
- Description: The Raven’s Coloured Progressive Matrices (CPM) test is used extensively across a wide variety of settings in South Africa, however more appropriate local normative data has yet to be established. The CPM is internationally recognised as a culture-fair test of nonverbal intelligence, designed for use with children between the ages of 5½ and 11½. This pilot study thus sought to establish normative data for this instrument for a population of Xhosa-speaking Primary School children in the peri-urban township area in the Grahamstown region. The booklet version of the test was used and it was administered in group format and according to an alternate method of test administration (using Xhosa instructions) developed by Vass in 1992. The final normative sample consisted of 197 male and 182 female Xhosa-speaking children in Grades Two to Seven (N=379). The results showed (1) a significant effect of age on test scores, where scores increased with age as expected; (2) a consistent tendency for males to outperform females was also noted, however small sample sizes precluded any categorical claims to this effect; (3) no significant effect of education on test scores was observed and finally; (4) and finally, it appeared that the norms generated for this study revealed a tendency to be lower than those obtained by Raven, Court and Raven (1990) during the standardisation of this instrument in the United Kingdom and America. The study concluded that (1) there is an urgent need for more appropriate South African normative data for this test; and (2) that when assessing African children from disadvantaged backgrounds, further research into the effects of cultural and socio-economic factors and gender on non-verbal intelligence (and on performance on this test in particular) is required.
- Full Text:
- Date Issued: 2000
Identification of Management skills required by middle Managers to effectively manage a public hospital in the Eastern Cape
- Authors: Belemu, Roy Boombe
- Date: 2000
- Subjects: Hospitals -- South Africa -- Management , Health services administration -- South Africa
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:10829 , http://hdl.handle.net/10948/19 , Hospitals -- South Africa -- Management , Health services administration -- South Africa
- Description: The research problem addressed in this study was to identify what management skills do middle managers require to manage the organisational units effectively. To achieve this objective a theoretical model of management skills required by middle managers to effectively manage a public hospital was developed, using relevant literature in which management skills are identified. The theoretical model consisted of the following categories of management skills whose correct application can promote managerial effectiveness in managing organisational units: General management skills; Technical skills; Human skills; Leadership skills; Financial management skills; Computer skills. Each category of the management skills was broken down into elements that were then analysed using literature identified during the literature study. The model was then used to develop a questionnaire to assess the degree to which managers responsible for running the clinical, nursing and paramedical departments of a public hospital in the Eastern Cape rate the elements in terms of importance. The empirical results obtained indicate that a wide variety of skills are regarded by middle managers as important to performance of their managerial roles. This resulted in the theoretical model being confirmed and the identified management skills being accepted as management skills required by middle managers to effectively manage a public hospital in the Eastern Cape.
- Full Text:
- Date Issued: 2000
- Authors: Belemu, Roy Boombe
- Date: 2000
- Subjects: Hospitals -- South Africa -- Management , Health services administration -- South Africa
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:10829 , http://hdl.handle.net/10948/19 , Hospitals -- South Africa -- Management , Health services administration -- South Africa
- Description: The research problem addressed in this study was to identify what management skills do middle managers require to manage the organisational units effectively. To achieve this objective a theoretical model of management skills required by middle managers to effectively manage a public hospital was developed, using relevant literature in which management skills are identified. The theoretical model consisted of the following categories of management skills whose correct application can promote managerial effectiveness in managing organisational units: General management skills; Technical skills; Human skills; Leadership skills; Financial management skills; Computer skills. Each category of the management skills was broken down into elements that were then analysed using literature identified during the literature study. The model was then used to develop a questionnaire to assess the degree to which managers responsible for running the clinical, nursing and paramedical departments of a public hospital in the Eastern Cape rate the elements in terms of importance. The empirical results obtained indicate that a wide variety of skills are regarded by middle managers as important to performance of their managerial roles. This resulted in the theoretical model being confirmed and the identified management skills being accepted as management skills required by middle managers to effectively manage a public hospital in the Eastern Cape.
- Full Text:
- Date Issued: 2000