Analyses of Retail and Transport Geography of Liquefied Petroleum Products in Ibadan metropolis, Nigeria
- Authors: Ajayi, Adeyinka Peter
- Date: 2019
- Subjects: Petroleum products
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/19065 , vital:40090
- Description: This study analyzed the effects that spatial arrangement of petroleum products retail outlets and the supply chain management techniques employed for products distribution (for both intra city and intercity shipments) have on the retailing dynamism of petroleum products within built environment and peripherals of Ibadan metropolis over the years. Specifically, the study investigated the differentials in the spatial configurations of petroleum products retail outlets between the core and periurban zones of the metropolis. An attempt was made to determine the explanatory variables that influence the spatial distributional decisions of petroleum products retail outlets in the metropolis. The study equally examined how the supply chain management (SCM) techniques by the different categories of the retail outlet owners influence the efficient and cost effective distribution of petroleum products. Lastly an attempt was made to analyze the relationship between the socio-economic attributes of the haulers and the achievement of compliance to the HSE stipulations guiding the conveyance of petroleum products. The theoretical underpinnings for the research were a derivative of the amalgamation of normative and psychological theories from geography, psychology, SCM and retailing science. Specifically, Expectation Disconfirmation Theory (EDT), Distributive Justice, Central Place Theory (CPT) Theories of Urban Impact (TUI) and Theory of Constraint (ToC) were the theories utilized in the study. For the achievement of the first objective which was to investigate the possible differential in the compliance rate between spatial pattern of fuel retail outlets in the core and peripheral zones of Ibadan metropolis, the first hypothesis of the study (which examined if there was no significant difference in the rate of compliance to the planning authority stipulations guiding the location pattern of petroleum product retail outlets between those located in the built up and xxiv peripheral zones of the city), was tested through the use of buffering and proximity analyses in the ArcMap environment of ArcGIS 10.1, while inferential statistical tool of an independent-samples t-test was conducted to compare the rate of compliance to the stipulations guiding the locations of these outlets in both the core and the peripheral zones. The result from the GIS analysis indicated that 33 (15.56%) out of the 220 outlets in the core zone of the metropolis complied with the planning stipulations guiding the location of fuel retail outlets. For the peripheral zone, out of the 220 fuel retail outlets 24 (10.90%) complied with the stipulations. The result from the t- test which was employed to test the hypothesis indicated that no significant difference existed in the rate of compliance t (263) =-2.66, p = 0.08 between fuel retail outlets in the core zone (M=3.9, SD=1.4) and peripheral zone (M=4.5, SD=1.79). The alternate hypothesis which stated that ―no significant difference existed in the compliance rate between fuel retail outlets located in the two zones‖ is accepted. For the achievement of the second objective of the study which was to analyze the factors which determine the location of fuel retail outlets both in the core and peripheral zones of Ibadan metropolis. All the managers/owners of the 432 fuel retail outlets in the metropolis were sampled out of which 256 questionnaires were retrieved for the purpose of this analysis. The breakdown of the socio-economic characteristics of the sampled respondents showed that the gender distribution showed that 194 (75.78%) of the respondents were males, while 64 (24.22 %) were females. The average age of the sampled population was 33.70 years. The mixed method was employed for the achievement of the second objective of this study. Logistic Regression Model (LRM) was employed to test the hypothesis and the result revealed that the inclusion of the independent variables in the model increased the overall level of it accuracy. The overall significance revealed that the Model Chi- xxv Square, derived from the likelihood fitted is also accurate (X2 = 43.47, df=5, p>.05). The model chi-square value of 43.47 (approximately 44% ) was significant. Thus, the indication is that the model has a good fit in predicting the possibility of a fuel retail outlet being located in the core or peripheral zone of the metropolis as determined by the explanatory variables (the independent variables accounted for about 44% of possible factors which determined whether a fuel retail outlets is located either within the core or peripheral zones of the metropolis. The remaining 56% are factors not considered in the study). The result gotten from the in depth interview sessions corroborated the findings from the tested hypothesis. The third objective was to examine the effects which the supply chain technique employed (either vertically integrated model or third-party arrangement) has on the achievement of efficient and effective distribution of the products. In order to achieve this objective, all the 389 registered members of Petroleum Tanker Drivers (PTD) association who are members of the PTD in the metropolis were sampled, 265 (around 70%) of the distributed questionnaires were retrieved and used for the analysis. In depth interview sessions were also conducted with three different managers of the three major conglomerates in the downstream sector of the Nigerian petroleum sector. The result of one-way between subjects (ANOVA) which was conducted to compare differences in the management and performances of haulage services outsourced to the 3PLS and those run under VIM showed that there was a significant effect of ownership type on management performance (F (2,262) = 60.26, p<.05). The null hypothesis was therefore rejected while the alternate hypothesis was accepted. The findings from the interview sessions posted similar results. The fourth and final objective was to analyze the effect that the socio-economic attributes of the participants (haulers and managers of retail outlets) involved in the distribution of xxvi petroleum products has on the safe, efficient and cost-effective distribution of product and this was done through the use of descriptive statistics, inferential statistics and incisive analysis of the interview sessions. A total number of 265 (70%) out of the 389 registered members of Petroleum Tanker Driver Association (PTDA) participated in the study. Multiple regression analysis (MRA) was used to test this hypothesis. The result from the statistical analysis show that the use of stimulant, work condition, marital status and educational attainment/literacy level have joint influence on compliance (R2 = 0.31, F (4,260) = 29.72, p<.05). On the basis of the foregoing, the hypothesis is thus accepted. The result from the interview sessions confirmed the existence of strong relationship between the explanatory variables and the hypothetical dependant variable. The study recommended a review of the planning processes guiding the establishment of fuel retail outlets. The study also advocated that retailers should endeavour to have stronger control over the supply chain of their products this could done by investing more in VIM rather than outsourcing such functions to 3PLs. This will help in better business performances. Government agencies in charge of monitoring drug abuse among haulers are advised to be more proactive by the duo of prevention and punishment strategies. This should include advocacy campaign against drug abuse. Different ranges of punishments should also be meted out for individual haulers found culpable.
- Full Text:
- Date Issued: 2019
- Authors: Ajayi, Adeyinka Peter
- Date: 2019
- Subjects: Petroleum products
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/19065 , vital:40090
- Description: This study analyzed the effects that spatial arrangement of petroleum products retail outlets and the supply chain management techniques employed for products distribution (for both intra city and intercity shipments) have on the retailing dynamism of petroleum products within built environment and peripherals of Ibadan metropolis over the years. Specifically, the study investigated the differentials in the spatial configurations of petroleum products retail outlets between the core and periurban zones of the metropolis. An attempt was made to determine the explanatory variables that influence the spatial distributional decisions of petroleum products retail outlets in the metropolis. The study equally examined how the supply chain management (SCM) techniques by the different categories of the retail outlet owners influence the efficient and cost effective distribution of petroleum products. Lastly an attempt was made to analyze the relationship between the socio-economic attributes of the haulers and the achievement of compliance to the HSE stipulations guiding the conveyance of petroleum products. The theoretical underpinnings for the research were a derivative of the amalgamation of normative and psychological theories from geography, psychology, SCM and retailing science. Specifically, Expectation Disconfirmation Theory (EDT), Distributive Justice, Central Place Theory (CPT) Theories of Urban Impact (TUI) and Theory of Constraint (ToC) were the theories utilized in the study. For the achievement of the first objective which was to investigate the possible differential in the compliance rate between spatial pattern of fuel retail outlets in the core and peripheral zones of Ibadan metropolis, the first hypothesis of the study (which examined if there was no significant difference in the rate of compliance to the planning authority stipulations guiding the location pattern of petroleum product retail outlets between those located in the built up and xxiv peripheral zones of the city), was tested through the use of buffering and proximity analyses in the ArcMap environment of ArcGIS 10.1, while inferential statistical tool of an independent-samples t-test was conducted to compare the rate of compliance to the stipulations guiding the locations of these outlets in both the core and the peripheral zones. The result from the GIS analysis indicated that 33 (15.56%) out of the 220 outlets in the core zone of the metropolis complied with the planning stipulations guiding the location of fuel retail outlets. For the peripheral zone, out of the 220 fuel retail outlets 24 (10.90%) complied with the stipulations. The result from the t- test which was employed to test the hypothesis indicated that no significant difference existed in the rate of compliance t (263) =-2.66, p = 0.08 between fuel retail outlets in the core zone (M=3.9, SD=1.4) and peripheral zone (M=4.5, SD=1.79). The alternate hypothesis which stated that ―no significant difference existed in the compliance rate between fuel retail outlets located in the two zones‖ is accepted. For the achievement of the second objective of the study which was to analyze the factors which determine the location of fuel retail outlets both in the core and peripheral zones of Ibadan metropolis. All the managers/owners of the 432 fuel retail outlets in the metropolis were sampled out of which 256 questionnaires were retrieved for the purpose of this analysis. The breakdown of the socio-economic characteristics of the sampled respondents showed that the gender distribution showed that 194 (75.78%) of the respondents were males, while 64 (24.22 %) were females. The average age of the sampled population was 33.70 years. The mixed method was employed for the achievement of the second objective of this study. Logistic Regression Model (LRM) was employed to test the hypothesis and the result revealed that the inclusion of the independent variables in the model increased the overall level of it accuracy. The overall significance revealed that the Model Chi- xxv Square, derived from the likelihood fitted is also accurate (X2 = 43.47, df=5, p>.05). The model chi-square value of 43.47 (approximately 44% ) was significant. Thus, the indication is that the model has a good fit in predicting the possibility of a fuel retail outlet being located in the core or peripheral zone of the metropolis as determined by the explanatory variables (the independent variables accounted for about 44% of possible factors which determined whether a fuel retail outlets is located either within the core or peripheral zones of the metropolis. The remaining 56% are factors not considered in the study). The result gotten from the in depth interview sessions corroborated the findings from the tested hypothesis. The third objective was to examine the effects which the supply chain technique employed (either vertically integrated model or third-party arrangement) has on the achievement of efficient and effective distribution of the products. In order to achieve this objective, all the 389 registered members of Petroleum Tanker Drivers (PTD) association who are members of the PTD in the metropolis were sampled, 265 (around 70%) of the distributed questionnaires were retrieved and used for the analysis. In depth interview sessions were also conducted with three different managers of the three major conglomerates in the downstream sector of the Nigerian petroleum sector. The result of one-way between subjects (ANOVA) which was conducted to compare differences in the management and performances of haulage services outsourced to the 3PLS and those run under VIM showed that there was a significant effect of ownership type on management performance (F (2,262) = 60.26, p<.05). The null hypothesis was therefore rejected while the alternate hypothesis was accepted. The findings from the interview sessions posted similar results. The fourth and final objective was to analyze the effect that the socio-economic attributes of the participants (haulers and managers of retail outlets) involved in the distribution of xxvi petroleum products has on the safe, efficient and cost-effective distribution of product and this was done through the use of descriptive statistics, inferential statistics and incisive analysis of the interview sessions. A total number of 265 (70%) out of the 389 registered members of Petroleum Tanker Driver Association (PTDA) participated in the study. Multiple regression analysis (MRA) was used to test this hypothesis. The result from the statistical analysis show that the use of stimulant, work condition, marital status and educational attainment/literacy level have joint influence on compliance (R2 = 0.31, F (4,260) = 29.72, p<.05). On the basis of the foregoing, the hypothesis is thus accepted. The result from the interview sessions confirmed the existence of strong relationship between the explanatory variables and the hypothetical dependant variable. The study recommended a review of the planning processes guiding the establishment of fuel retail outlets. The study also advocated that retailers should endeavour to have stronger control over the supply chain of their products this could done by investing more in VIM rather than outsourcing such functions to 3PLs. This will help in better business performances. Government agencies in charge of monitoring drug abuse among haulers are advised to be more proactive by the duo of prevention and punishment strategies. This should include advocacy campaign against drug abuse. Different ranges of punishments should also be meted out for individual haulers found culpable.
- Full Text:
- Date Issued: 2019
Factors associated with consistent condom use: a cross-sectional survey of two Nigerian universities
- Ajayi, Anthony Idowu, Ismail , Kafayat Olanike, Akpan, Wilson
- Authors: Ajayi, Anthony Idowu , Ismail , Kafayat Olanike , Akpan, Wilson
- Date: 2019
- Subjects: Nigeria Condom Use Computer File
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/5834 , vital:44650 , https://DOI:10.1186/s12889-019-7543-1
- Description: Background: Consistent condom use is central to the prevention of transmission of human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs), especially among young adults. This study drew from a cross-sectional survey of two Nigerian universities to determine the level of consistent condom use, explored the determinants of condom use consistency and reasons for inconsistent condom use. Methods: We adopted a descriptive cross-sectional design, which involves the recruitment of 800 male and female students using stratified random sampling. Adjusted and unadjusted logistic regression models were used to examine the factors associated with consistent condom use among a final sample of 498 students who engaged in sex in the last year preceding the study. Results: Only 38.6% of sexually active participants (n = 498) used condoms consistently in the previous year. High condom self-efficacy score (AOR: 2.40; 95% CI: 1.58–3.64), discussion of HIV/STIs with sexual partner (AOR: 1.91; 95%CI: 1.29–2.83), knowing partner’s HIV status (AOR: 1.48; 95% CI: 1.02–2.16), being students of university located in a high HIV prevalence area (AOR: 2.86; 95% CI: 1.92–4.28) and engaging in sex with only steady partner (AOR: 1.74; 95% CI: 1.17–2.60) were associated with a higher odds of consistent condom use. Trust, unavailability of condoms, dislike of condoms and a perception that condoms reduced sexual pleasure were the main reasons for inconsistent use of condoms. Conclusion: The study found a low level of consistent condom use among study participants. Counselling young adults in Nigeria on condom self-efficacy, providing condoms on campuses and encouraging the discussion of sexually transmitted infections with sexual partners are central to improving the level of consistent condom use among Nigerian university students. Keywords: Condoms, Self-efficacy, Consistent condom use, HIV, Drug use, Alcohol use, Nigeria, University students
- Full Text:
- Date Issued: 2019
Factors associated with consistent condom use: a cross-sectional survey of two Nigerian universities
- Authors: Ajayi, Anthony Idowu , Ismail , Kafayat Olanike , Akpan, Wilson
- Date: 2019
- Subjects: Nigeria Condom Use Computer File
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/5834 , vital:44650 , https://DOI:10.1186/s12889-019-7543-1
- Description: Background: Consistent condom use is central to the prevention of transmission of human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs), especially among young adults. This study drew from a cross-sectional survey of two Nigerian universities to determine the level of consistent condom use, explored the determinants of condom use consistency and reasons for inconsistent condom use. Methods: We adopted a descriptive cross-sectional design, which involves the recruitment of 800 male and female students using stratified random sampling. Adjusted and unadjusted logistic regression models were used to examine the factors associated with consistent condom use among a final sample of 498 students who engaged in sex in the last year preceding the study. Results: Only 38.6% of sexually active participants (n = 498) used condoms consistently in the previous year. High condom self-efficacy score (AOR: 2.40; 95% CI: 1.58–3.64), discussion of HIV/STIs with sexual partner (AOR: 1.91; 95%CI: 1.29–2.83), knowing partner’s HIV status (AOR: 1.48; 95% CI: 1.02–2.16), being students of university located in a high HIV prevalence area (AOR: 2.86; 95% CI: 1.92–4.28) and engaging in sex with only steady partner (AOR: 1.74; 95% CI: 1.17–2.60) were associated with a higher odds of consistent condom use. Trust, unavailability of condoms, dislike of condoms and a perception that condoms reduced sexual pleasure were the main reasons for inconsistent use of condoms. Conclusion: The study found a low level of consistent condom use among study participants. Counselling young adults in Nigeria on condom self-efficacy, providing condoms on campuses and encouraging the discussion of sexually transmitted infections with sexual partners are central to improving the level of consistent condom use among Nigerian university students. Keywords: Condoms, Self-efficacy, Consistent condom use, HIV, Drug use, Alcohol use, Nigeria, University students
- Full Text:
- Date Issued: 2019
Taxonomic and trait-based responses of the orders Ephemeroptera, Plecoptera, Odonata, And Trichoptera (EPOT) to sediment stress in the Tsitsa River and its tributaries, Eastern Cape, South Africa
- Akamagwuna, Frank Chukwuzuoke
- Authors: Akamagwuna, Frank Chukwuzuoke
- Date: 2019
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/68082 , vital:29196
- Description: Increased urbanization and industrialisation due to human population growth and associated high demand for food have led to widespread disturbances of freshwater ecosystems and associated resources. A widely recognised consequence of these disturbances is the excessive delivery of sediments into the freshwater ecosystems, which severely affects the functioning and integrity of these systems.. The major water quality impairment in the Tsitsa River and its tributaries, situated in the Mzimvubu catchment in the Eastern Cape Province of South Africa, is known to be excessive sediment input. In this study, the application of macroinvertebrates taxonomic-based and trait-based approaches was used to assess the responses and vulnerability of Ephemeroptera, Plecoptera, Odonata and Trichoptera (EPOT) species to settled and suspended sediments stress in eight selected sampling sites in the Tsitsa River and its tributaries. The eight selected sites were Site 1 (Tsitsa upstream), Site 2 (Tsitsa downstream), Site 3 (Qurana tributary), Site 4 (Pot River upstream), Site 5 (Pot River downstream), Site 6 (Little Pot River), Site 7 (Millstream upstream) and Site 8 (Millstream downstream). The methods used in this study involved the analysis of water physico-chemical variables as well as sediment characteristics, derivation of five EPOT metrics, EPOT species-level taxonomic analysis, individual EPOT trait analysis and the development of a novel trait-based approach using a combination of traits. The sampling of EPOT taxa was done using the SASS5 protocols. Identification of EPOT was done to genus/species level and all data were subjected to relevant statistical analysis. The results of ecological categories derived for the physico-chemical variables generally indicated the ecological categories A and B, which was indicative of good water quality conditions. The result of sediment particle analysis revealed four distinct site groups: site group 1 (Tsitsa River upstream and Qurana tributary), site group 2 (Tsitsa River downstream and Millstream upstream), site group 3 (Pot River, both upstream and downstream, and Millstream downstream) and site group 4 (Little Pot River). The species-level taxonomic analysis of EPOT revealed that site group 1 was the most sediment-influenced sites whereas site group 4 was the least sediment-influenced. Species such as Paragopmhus sp., Aeshna sp. and Baetis sp. were considered sediment-tolerant with strong positive association with site group 1. The novel trait-based approach developed in this study proved useful in predicting the responses of EPOT species to sediment stress, and further discriminated between the study sites. The approach was used to group EPOT species into four vulnerability classes. The result showed that filter feeding EPOT species that have filamentous gills, preferring stone biotopes and feeding on detritus (FPOM) were mostly classified as highly vulnerable to sediment stress and indicated no significant association with the highly sediment-influenced site group 1. The TBA largely corresponded well to the predictions made with the relative abundance of the vulnerable class decreasing in the sediment-influenced sites compared to the tolerant and highly tolerant classes. Overall, the study revealed the importance of the complementary use of taxonomic and trait-based approaches to biomonitoring.
- Full Text:
- Date Issued: 2019
- Authors: Akamagwuna, Frank Chukwuzuoke
- Date: 2019
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/68082 , vital:29196
- Description: Increased urbanization and industrialisation due to human population growth and associated high demand for food have led to widespread disturbances of freshwater ecosystems and associated resources. A widely recognised consequence of these disturbances is the excessive delivery of sediments into the freshwater ecosystems, which severely affects the functioning and integrity of these systems.. The major water quality impairment in the Tsitsa River and its tributaries, situated in the Mzimvubu catchment in the Eastern Cape Province of South Africa, is known to be excessive sediment input. In this study, the application of macroinvertebrates taxonomic-based and trait-based approaches was used to assess the responses and vulnerability of Ephemeroptera, Plecoptera, Odonata and Trichoptera (EPOT) species to settled and suspended sediments stress in eight selected sampling sites in the Tsitsa River and its tributaries. The eight selected sites were Site 1 (Tsitsa upstream), Site 2 (Tsitsa downstream), Site 3 (Qurana tributary), Site 4 (Pot River upstream), Site 5 (Pot River downstream), Site 6 (Little Pot River), Site 7 (Millstream upstream) and Site 8 (Millstream downstream). The methods used in this study involved the analysis of water physico-chemical variables as well as sediment characteristics, derivation of five EPOT metrics, EPOT species-level taxonomic analysis, individual EPOT trait analysis and the development of a novel trait-based approach using a combination of traits. The sampling of EPOT taxa was done using the SASS5 protocols. Identification of EPOT was done to genus/species level and all data were subjected to relevant statistical analysis. The results of ecological categories derived for the physico-chemical variables generally indicated the ecological categories A and B, which was indicative of good water quality conditions. The result of sediment particle analysis revealed four distinct site groups: site group 1 (Tsitsa River upstream and Qurana tributary), site group 2 (Tsitsa River downstream and Millstream upstream), site group 3 (Pot River, both upstream and downstream, and Millstream downstream) and site group 4 (Little Pot River). The species-level taxonomic analysis of EPOT revealed that site group 1 was the most sediment-influenced sites whereas site group 4 was the least sediment-influenced. Species such as Paragopmhus sp., Aeshna sp. and Baetis sp. were considered sediment-tolerant with strong positive association with site group 1. The novel trait-based approach developed in this study proved useful in predicting the responses of EPOT species to sediment stress, and further discriminated between the study sites. The approach was used to group EPOT species into four vulnerability classes. The result showed that filter feeding EPOT species that have filamentous gills, preferring stone biotopes and feeding on detritus (FPOM) were mostly classified as highly vulnerable to sediment stress and indicated no significant association with the highly sediment-influenced site group 1. The TBA largely corresponded well to the predictions made with the relative abundance of the vulnerable class decreasing in the sediment-influenced sites compared to the tolerant and highly tolerant classes. Overall, the study revealed the importance of the complementary use of taxonomic and trait-based approaches to biomonitoring.
- Full Text:
- Date Issued: 2019
A pilot wide-field VLBI survey of the GOODS-North field
- Authors: Akoto-Danso, Alexander
- Date: 2019
- Subjects: Radio astronomy , Very long baseline interferometry , Radio interometers , Imaging systems in astronomy , Hubble Space Telescope (Spacecraft) -- Observations
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/72296 , vital:30027
- Description: Very Long Baseline Interferometry (VLBI) has significant advantages in disentangling active galactic nuclei (AGN) from star formation, particularly at intermediate to high-redshift due to its high angular resolution and insensitivity to dust. Surveys using VLBI arrays are only just becoming practical over wide areas with numerous developments and innovations (such as multi-phase centre techniques) in observation and data analysis techniques. However, fully automated pipelines for VLBI data analysis are based on old software packages and are unable to incorporate new calibration and imaging algorithms. In this work, the researcher developed a pipeline for VLBI data analysis which integrates a recent wide-field imaging algorithm, RFI excision, and a purpose-built source finding algorithm specifically developed for the 64kx64k wide-field VLBI images. The researcher used this novel pipeline to process 6% (~ 9 arcmin2 of the total 160 arcmin2) of the data from the CANDELS GOODS- North extragalactic field at 1.6 GHz. The milli-arcsec scale images have an average rms of a ~ 10 uJy/beam. Forty four (44) candidate sources were detected, most of which are at sub-mJy flux densities, having brightness temperatures and luminosities of >5x105 K and >6x1021 W Hz-1 respectively. This work demonstrates that automated post-processing pipelines for wide-field, uniform sensitivity VLBI surveys are feasible and indeed made more efficient with new software, wide-field imaging algorithms and more purpose-built source- finders. This broadens the discovery space for future wide-field surveys with upcoming arrays such as the African VLBI Network (AVN), MeerKAT and the Square Kilometre Array (SKA).
- Full Text:
- Date Issued: 2019
- Authors: Akoto-Danso, Alexander
- Date: 2019
- Subjects: Radio astronomy , Very long baseline interferometry , Radio interometers , Imaging systems in astronomy , Hubble Space Telescope (Spacecraft) -- Observations
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/72296 , vital:30027
- Description: Very Long Baseline Interferometry (VLBI) has significant advantages in disentangling active galactic nuclei (AGN) from star formation, particularly at intermediate to high-redshift due to its high angular resolution and insensitivity to dust. Surveys using VLBI arrays are only just becoming practical over wide areas with numerous developments and innovations (such as multi-phase centre techniques) in observation and data analysis techniques. However, fully automated pipelines for VLBI data analysis are based on old software packages and are unable to incorporate new calibration and imaging algorithms. In this work, the researcher developed a pipeline for VLBI data analysis which integrates a recent wide-field imaging algorithm, RFI excision, and a purpose-built source finding algorithm specifically developed for the 64kx64k wide-field VLBI images. The researcher used this novel pipeline to process 6% (~ 9 arcmin2 of the total 160 arcmin2) of the data from the CANDELS GOODS- North extragalactic field at 1.6 GHz. The milli-arcsec scale images have an average rms of a ~ 10 uJy/beam. Forty four (44) candidate sources were detected, most of which are at sub-mJy flux densities, having brightness temperatures and luminosities of >5x105 K and >6x1021 W Hz-1 respectively. This work demonstrates that automated post-processing pipelines for wide-field, uniform sensitivity VLBI surveys are feasible and indeed made more efficient with new software, wide-field imaging algorithms and more purpose-built source- finders. This broadens the discovery space for future wide-field surveys with upcoming arrays such as the African VLBI Network (AVN), MeerKAT and the Square Kilometre Array (SKA).
- Full Text:
- Date Issued: 2019
Effect of service and collaborative learning strategies on students’ environmental knowledge in selected junior secondary schools in Oyo State, Nigeria
- Authors: Alalade, Olufiropo Emmanuel
- Date: 2019
- Subjects: Service learning Environmental management
- Language: English
- Type: Thesis , Doctoral , PhD (Education)
- Identifier: http://hdl.handle.net/10353/16602 , vital:40736
- Description: Though many strategies have helped in increasing students’ knowledge and awareness about environmental issues, yet, environmental challenges and problems are still on the increase in Nigeria. This may be due to the fact that environmental issues are controversial and require collaborative efforts of all citizens, especially school students. This study determined the effects of service learning and collaborative learning in social studies on Junior Secondary School students’ environmental literacy. It also explored the moderating effects of school location and gender. The study adopted a pretest-posttest, control group, quasiexperimental design. Multi-stage sampling technique was employed. Six (6) secondary schools that are co-educational from Ibadan were purposively selected based on presence of environmental challenges in their immediate environment. There were three (3) schools from Ibadan city (urban area of Ibadan) and three (3) from Ibadan less city (rural area of Ibadan). Seven hypotheses were tested at 0.05 level of significance. Five research instruments were used for the study, these were; Environmental Knowledge Test (EKT, r = 0.76), Environmental Attitude Questionnaire (EAQ, r = 0.85), Service Learning Guide (SLG, r = 0.71), Collaborative Learning Guide (CLG, r = 0.66) and Conventional Learning Guide (CLG, r = 0.73). Analysis of Covariance (ANCOVA) was used in testing the seven formulated hypotheses. Scheffé Post-hoc analysis was carried out to determine the source of significant effect of treatment. Significant interaction effect was described using graphical representation. All hypotheses were tested at P< .05 level of significance. The results revealed that there was a significant main effect of treatment (service and collaborative learning strategies) on junior secondary school students’ environmental knowledge (F(2,582) = 824.98; p<0.05, partial η2 = 0.739), with an effect of 73.9%. There was also a significant main effect of treatment (service and collaborative learning strategies) on junior secondary school students’ environmental attitude (F(2,582) = 1317.79; p<0.05, partial η2 = 0.819). The findings showed that there was a significant main effect of gender (male/female) on junior secondary school students’ environmental knowledge (F(1,582) = 3.99; p<0.05, v partial η2 = 0.007) but there was no significant main effect of school location (urban/rural) on junior secondary school students’ environmental knowledge (F(1,582) = 0.08; p>.05, partial η2 = 0.00). Based on these findings, it was recommended that teachers should adopt service learning and collaborative learning strategies in the teaching of environmental concepts and problems in Social Studies in order to improve students’ performance in Social Studies. Teachers should facilitate the use of service learning and collaborative learning strategies in schools to improve students’ environmental problem-solving skills and their achievement in the subject. Teaching institutions should not only include service learning and collaborative learning strategies in their curriculum but should endeavour to provide practical experience for pre-service teachers to be well grounded and equipped on the use of these strategies.
- Full Text:
- Date Issued: 2019
- Authors: Alalade, Olufiropo Emmanuel
- Date: 2019
- Subjects: Service learning Environmental management
- Language: English
- Type: Thesis , Doctoral , PhD (Education)
- Identifier: http://hdl.handle.net/10353/16602 , vital:40736
- Description: Though many strategies have helped in increasing students’ knowledge and awareness about environmental issues, yet, environmental challenges and problems are still on the increase in Nigeria. This may be due to the fact that environmental issues are controversial and require collaborative efforts of all citizens, especially school students. This study determined the effects of service learning and collaborative learning in social studies on Junior Secondary School students’ environmental literacy. It also explored the moderating effects of school location and gender. The study adopted a pretest-posttest, control group, quasiexperimental design. Multi-stage sampling technique was employed. Six (6) secondary schools that are co-educational from Ibadan were purposively selected based on presence of environmental challenges in their immediate environment. There were three (3) schools from Ibadan city (urban area of Ibadan) and three (3) from Ibadan less city (rural area of Ibadan). Seven hypotheses were tested at 0.05 level of significance. Five research instruments were used for the study, these were; Environmental Knowledge Test (EKT, r = 0.76), Environmental Attitude Questionnaire (EAQ, r = 0.85), Service Learning Guide (SLG, r = 0.71), Collaborative Learning Guide (CLG, r = 0.66) and Conventional Learning Guide (CLG, r = 0.73). Analysis of Covariance (ANCOVA) was used in testing the seven formulated hypotheses. Scheffé Post-hoc analysis was carried out to determine the source of significant effect of treatment. Significant interaction effect was described using graphical representation. All hypotheses were tested at P< .05 level of significance. The results revealed that there was a significant main effect of treatment (service and collaborative learning strategies) on junior secondary school students’ environmental knowledge (F(2,582) = 824.98; p<0.05, partial η2 = 0.739), with an effect of 73.9%. There was also a significant main effect of treatment (service and collaborative learning strategies) on junior secondary school students’ environmental attitude (F(2,582) = 1317.79; p<0.05, partial η2 = 0.819). The findings showed that there was a significant main effect of gender (male/female) on junior secondary school students’ environmental knowledge (F(1,582) = 3.99; p<0.05, v partial η2 = 0.007) but there was no significant main effect of school location (urban/rural) on junior secondary school students’ environmental knowledge (F(1,582) = 0.08; p>.05, partial η2 = 0.00). Based on these findings, it was recommended that teachers should adopt service learning and collaborative learning strategies in the teaching of environmental concepts and problems in Social Studies in order to improve students’ performance in Social Studies. Teachers should facilitate the use of service learning and collaborative learning strategies in schools to improve students’ environmental problem-solving skills and their achievement in the subject. Teaching institutions should not only include service learning and collaborative learning strategies in their curriculum but should endeavour to provide practical experience for pre-service teachers to be well grounded and equipped on the use of these strategies.
- Full Text:
- Date Issued: 2019
An experimental study of self-regulated learning with mildly gifted learners in grade 3 mathematics
- Authors: Allers, Amanda Lynette
- Date: 2019
- Subjects: Gifted children -- Education , Motivation in education Academic achievement Mathematics -- Study and teaching (Primary)
- Language: English
- Type: Thesis , Doctoral , DEd
- Identifier: http://hdl.handle.net/10948/42074 , vital:36623
- Description: The study investigated whether self-regulated learning (SRL) strategies can be used successfully by Grade 3 mildly gifted learners (MGLs), in order to master an enriched advanced level mathematics curriculum. In accordance with internationally and nationally accepted principles, learners of diverse abilities should be given equal opportunities to achieve their full learning potential. The stark reality is that rigid application of the national curriculum currently used in South African primary schools, limits this ideal. MGLs possess skills that enable them to study at an increased level, a quicker pace and with an advanced degree of independence. The study employed the true experimental research. Sixty-four learners participated in the Mathematics Enrichment Programme. Purposive sampling was used to identify and select these learners. Subsequent to SRL pre-tests, simple random sampling was used to determine the experimental and control groups. The experimental group used problem-solving and 21st Century technology to develop SRL strategies. Direct teaching strategies were used for the control group. Learners were administered pre-tests, diagnostic problem-solving assessments, and post-tests relating to problem-solving and SRL. Chi-square tests and inferential t-tests were employed to draw comparisons within and between the groups regarding SRL and problem-solving scores. Univariate ANCOVAs were conducted to determine the post-test differences. Furthermore, Cronbach alpha was used to measure reliability of summated scores relating to SRL and problem-solving. The empirical results suggest that MGLs in Grade 3 are indeed capable of self-regulating their learning. This enhanced learners’ self-determination, self-confidence, self-motivation, self-independence, and self-empowerment in relation to their tasks. The empirical results suggest a significant constructive addition to the present standard curriculum for MGLs in the mainstream of education. The self-regulatory model for Foundation Phase MGLs which evolved from this study can be successfully employed to balance the diversity challenges in an inclusive education system. The findings of this study can have significant implications for future teacher training and education of MGLs in primary schools.
- Full Text:
- Date Issued: 2019
- Authors: Allers, Amanda Lynette
- Date: 2019
- Subjects: Gifted children -- Education , Motivation in education Academic achievement Mathematics -- Study and teaching (Primary)
- Language: English
- Type: Thesis , Doctoral , DEd
- Identifier: http://hdl.handle.net/10948/42074 , vital:36623
- Description: The study investigated whether self-regulated learning (SRL) strategies can be used successfully by Grade 3 mildly gifted learners (MGLs), in order to master an enriched advanced level mathematics curriculum. In accordance with internationally and nationally accepted principles, learners of diverse abilities should be given equal opportunities to achieve their full learning potential. The stark reality is that rigid application of the national curriculum currently used in South African primary schools, limits this ideal. MGLs possess skills that enable them to study at an increased level, a quicker pace and with an advanced degree of independence. The study employed the true experimental research. Sixty-four learners participated in the Mathematics Enrichment Programme. Purposive sampling was used to identify and select these learners. Subsequent to SRL pre-tests, simple random sampling was used to determine the experimental and control groups. The experimental group used problem-solving and 21st Century technology to develop SRL strategies. Direct teaching strategies were used for the control group. Learners were administered pre-tests, diagnostic problem-solving assessments, and post-tests relating to problem-solving and SRL. Chi-square tests and inferential t-tests were employed to draw comparisons within and between the groups regarding SRL and problem-solving scores. Univariate ANCOVAs were conducted to determine the post-test differences. Furthermore, Cronbach alpha was used to measure reliability of summated scores relating to SRL and problem-solving. The empirical results suggest that MGLs in Grade 3 are indeed capable of self-regulating their learning. This enhanced learners’ self-determination, self-confidence, self-motivation, self-independence, and self-empowerment in relation to their tasks. The empirical results suggest a significant constructive addition to the present standard curriculum for MGLs in the mainstream of education. The self-regulatory model for Foundation Phase MGLs which evolved from this study can be successfully employed to balance the diversity challenges in an inclusive education system. The findings of this study can have significant implications for future teacher training and education of MGLs in primary schools.
- Full Text:
- Date Issued: 2019
Where dreams become reality: professionalism in flight training in the Eastern Cape
- Authors: Allison, Martin
- Date: 2019
- Subjects: Professional socialization , Flight training -- South Africa , Flight schools -- South Africa -- Case studies , Air pilots -- Training of -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/95376 , vital:31150
- Description: This study explores the construction of the identity of professional pilots through a case study of a flying school in South Africa. Here, a 15-20-month period of intensive study and training of students, fresh from school or college, leads in most cases to the attainment of a Commercial or Airline Transport Pilot’s Licence. The construction of identity is a continuous process and a lifelong project and hence this study can only reflect upon the factors influencing the early stages of a pilot’s career, until the point where the licenced Pilot leaves the Air School and enters full time employment with a commercial undertaking, but it is argued that this is a crucial step in the formation of professional identity, habitus in Bourdieu’s terms. The culture of the air School reflects the military background of the founders of the school and the staff employed in senior positions. The school, which is residential, observes a strict regime of Ground School and Practical Flying Training and a high standard of performance and personal conduct is demanded, both during training and in off duty hours and excessive consumption of alcohol and smoking are discouraged, and drug use absolutely taboo. Progress with training at the school is closely monitored and a disciplined environment maintained by surveillance cameras, house monitors and security guards; in Foucauldian terms, a modern version of the Panopticon, but somewhat less than Goffman’s Total Institution. It was found that the construction of a flying identity for most of the students entering the air school commenced in childhood or early adulthood, through the influence of friends and relatives and they enter the school with the firm intention of becoming Professional pilots. Full participation of the author in the Ground School revealed how professionalization is implemented through the discipline and rigor of the training methods employed. Through mastery of a complex body of theoretical knowledge in the Ground School and the practical skill of learning to fly in a one-on-one relationship with an instructor, the students gain confidence and efficacy which contributes to their self-respect and maturity. The international reputation of the school, confers prestige upon its graduates and they benefit from membership of a profession which commands respect and a high level of income. In large measure, the thesis shows, the success of the School is a function of the founders’ ‘invention of tradition’ focusing on the wartime training school that existed on the site and the many echoes of those times in the (re)construction of its buildings and facilities, continuing in the approach of the multinational that now owns the School.
- Full Text:
- Date Issued: 2019
- Authors: Allison, Martin
- Date: 2019
- Subjects: Professional socialization , Flight training -- South Africa , Flight schools -- South Africa -- Case studies , Air pilots -- Training of -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/95376 , vital:31150
- Description: This study explores the construction of the identity of professional pilots through a case study of a flying school in South Africa. Here, a 15-20-month period of intensive study and training of students, fresh from school or college, leads in most cases to the attainment of a Commercial or Airline Transport Pilot’s Licence. The construction of identity is a continuous process and a lifelong project and hence this study can only reflect upon the factors influencing the early stages of a pilot’s career, until the point where the licenced Pilot leaves the Air School and enters full time employment with a commercial undertaking, but it is argued that this is a crucial step in the formation of professional identity, habitus in Bourdieu’s terms. The culture of the air School reflects the military background of the founders of the school and the staff employed in senior positions. The school, which is residential, observes a strict regime of Ground School and Practical Flying Training and a high standard of performance and personal conduct is demanded, both during training and in off duty hours and excessive consumption of alcohol and smoking are discouraged, and drug use absolutely taboo. Progress with training at the school is closely monitored and a disciplined environment maintained by surveillance cameras, house monitors and security guards; in Foucauldian terms, a modern version of the Panopticon, but somewhat less than Goffman’s Total Institution. It was found that the construction of a flying identity for most of the students entering the air school commenced in childhood or early adulthood, through the influence of friends and relatives and they enter the school with the firm intention of becoming Professional pilots. Full participation of the author in the Ground School revealed how professionalization is implemented through the discipline and rigor of the training methods employed. Through mastery of a complex body of theoretical knowledge in the Ground School and the practical skill of learning to fly in a one-on-one relationship with an instructor, the students gain confidence and efficacy which contributes to their self-respect and maturity. The international reputation of the school, confers prestige upon its graduates and they benefit from membership of a profession which commands respect and a high level of income. In large measure, the thesis shows, the success of the School is a function of the founders’ ‘invention of tradition’ focusing on the wartime training school that existed on the site and the many echoes of those times in the (re)construction of its buildings and facilities, continuing in the approach of the multinational that now owns the School.
- Full Text:
- Date Issued: 2019
Construction material logistics management: the case of north-central Nigeria
- Authors: Alumbugu, Polycarp Olaku
- Date: 2019
- Subjects: Construction projects-- Nigeria --Management Construction projects --Management Logistics-- Nigeria -- Management , Construction industry -- Nigeria
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/44879 , vital:38179
- Description: The Management of Construction Material Logistics Systems plays a significant role in meeting the goals of cost, quality and time to completion of a construction project. Studies have revealed that the cost of construction materials is usually about 50%-60% of the total cost of the project and that the logistic cost accounts for between 17%-35% of the cost material. Fundamentally, it is accepted that any inefficiency in the delivery of construction material could lead to a time overrun and thus, a rise in construction costs addressing the operational performance of logistics would have a positive impact on the goals of a construction project. The aim of this study was to investigate and evaluate the operational performance of material logistics in North-Central Nigeria as there is little specific research conducted on its effectiveness and efficiency. The methodology used included an extensive literature review and a field study conducted on ten quantitative approach that is rooted in the positivist paradigm, and purposive sampling techniques, was adopted. The descriptive method of data analysis was employed, and the findings and interpretations presented through graphs and images. Analysis of the findings led to the conclusion that material logistics did not operate as a system. There was almost no collaboration and integration of the logistics systems to create a synergistic interrelationship between functions in pursuit of higher overall effectiveness and efficiency. Improvement was needed in warehouse and transport operations and processes; technology and automation of logistics operations were absent, and delivery of material to customers was not effective. The implication was that the current materials logistics system did not meet the delivery goals of cost, quality and time of a construction project. The recommendations suggested included the adoption of the framework developed in this study. This would serve as a guide towards effective and efficient logistics management for material manufacturing firms, and for construction professionals.
- Full Text:
- Date Issued: 2019
- Authors: Alumbugu, Polycarp Olaku
- Date: 2019
- Subjects: Construction projects-- Nigeria --Management Construction projects --Management Logistics-- Nigeria -- Management , Construction industry -- Nigeria
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/44879 , vital:38179
- Description: The Management of Construction Material Logistics Systems plays a significant role in meeting the goals of cost, quality and time to completion of a construction project. Studies have revealed that the cost of construction materials is usually about 50%-60% of the total cost of the project and that the logistic cost accounts for between 17%-35% of the cost material. Fundamentally, it is accepted that any inefficiency in the delivery of construction material could lead to a time overrun and thus, a rise in construction costs addressing the operational performance of logistics would have a positive impact on the goals of a construction project. The aim of this study was to investigate and evaluate the operational performance of material logistics in North-Central Nigeria as there is little specific research conducted on its effectiveness and efficiency. The methodology used included an extensive literature review and a field study conducted on ten quantitative approach that is rooted in the positivist paradigm, and purposive sampling techniques, was adopted. The descriptive method of data analysis was employed, and the findings and interpretations presented through graphs and images. Analysis of the findings led to the conclusion that material logistics did not operate as a system. There was almost no collaboration and integration of the logistics systems to create a synergistic interrelationship between functions in pursuit of higher overall effectiveness and efficiency. Improvement was needed in warehouse and transport operations and processes; technology and automation of logistics operations were absent, and delivery of material to customers was not effective. The implication was that the current materials logistics system did not meet the delivery goals of cost, quality and time of a construction project. The recommendations suggested included the adoption of the framework developed in this study. This would serve as a guide towards effective and efficient logistics management for material manufacturing firms, and for construction professionals.
- Full Text:
- Date Issued: 2019
Construction material logistics management: the case of North-Central Nigeria
- Authors: Alumbugu, Polycarp Olaku
- Date: 2019
- Subjects: Construction industry -- Nigeria
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/44556 , vital:38132
- Description: The Management of Construction Material Logistics Systems plays a significant role in meeting the goals of cost, quality and time to completion of a construction project. Fundamentally, it is accepted that any inefficiency in the delivery of construction material could lead to a time overrun and thus, a rise in construction costs. Therefore addressing the operational performance of logistics would have a positive impact on the goals of a construction project. The aim of this study was to investigate and evaluate the operational performance of material logistics in North-Central Nigeria as there is little specific research conducted on its effectiveness and efficiency. The methodology used included an extensive literature review and a field study conducted on ten quantitative approach that is rooted in the positivist paradigm, and purposive sampling techniques, was adopted. The descriptive method of data analysis was employed, and the findings and interpretations presented through graphs and images. Analysis of the findings led to the conclusion that material logistics did not operate as a system. There was almost no collaboration and integration of the logistics systems to create a synergistic interrelationship between functions in pursuit of higher overall effectiveness and efficiency. Improvement was needed in warehouse and transport operations and processes; technology and automation of logistics operations were absent, and delivery of material to customers was not effective. The implication was that the current materials logistics system did not meet the delivery goals of cost, quality and time of a construction project. The recommendations suggested included the adoption of the framework developed in this study. This would serve as a guide towards effective and efficient logistics management for material manufacturing firms, and for construction professionals.
- Full Text:
- Date Issued: 2019
- Authors: Alumbugu, Polycarp Olaku
- Date: 2019
- Subjects: Construction industry -- Nigeria
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/44556 , vital:38132
- Description: The Management of Construction Material Logistics Systems plays a significant role in meeting the goals of cost, quality and time to completion of a construction project. Fundamentally, it is accepted that any inefficiency in the delivery of construction material could lead to a time overrun and thus, a rise in construction costs. Therefore addressing the operational performance of logistics would have a positive impact on the goals of a construction project. The aim of this study was to investigate and evaluate the operational performance of material logistics in North-Central Nigeria as there is little specific research conducted on its effectiveness and efficiency. The methodology used included an extensive literature review and a field study conducted on ten quantitative approach that is rooted in the positivist paradigm, and purposive sampling techniques, was adopted. The descriptive method of data analysis was employed, and the findings and interpretations presented through graphs and images. Analysis of the findings led to the conclusion that material logistics did not operate as a system. There was almost no collaboration and integration of the logistics systems to create a synergistic interrelationship between functions in pursuit of higher overall effectiveness and efficiency. Improvement was needed in warehouse and transport operations and processes; technology and automation of logistics operations were absent, and delivery of material to customers was not effective. The implication was that the current materials logistics system did not meet the delivery goals of cost, quality and time of a construction project. The recommendations suggested included the adoption of the framework developed in this study. This would serve as a guide towards effective and efficient logistics management for material manufacturing firms, and for construction professionals.
- Full Text:
- Date Issued: 2019
Integrated computational approaches and tools for allosteric drug discovery:
- Amamuddy, Olivier S, Veldman, Wade, Manyumwa, Colleen, Khairallah, Afrah, Agajanian, Steve, Oluyemi, Odeyemi, Verkhivker, Gennady M, Tastan Bishop, Özlem
- Authors: Amamuddy, Olivier S , Veldman, Wade , Manyumwa, Colleen , Khairallah, Afrah , Agajanian, Steve , Oluyemi, Odeyemi , Verkhivker, Gennady M , Tastan Bishop, Özlem
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163012 , vital:41004 , https://doi.org/10.3390/ijms21030847
- Description: Understanding molecular mechanisms underlying the complexity of allosteric regulation in proteins has attracted considerable attention in drug discovery due to the benefits and versatility of allosteric modulators in providing desirable selectivity against protein targets while minimizing toxicity and other side effects. The proliferation of novel computational approaches for predicting ligand–protein interactions and binding using dynamic and network-centric perspectives has led to new insights into allosteric mechanisms and facilitated computer-based discovery of allosteric drugs. Although no absolute method of experimental and in silico allosteric drug/site discovery exists, current methods are still being improved. As such, the critical analysis and integration of established approaches into robust, reproducible, and customizable computational pipelines with experimental feedback could make allosteric drug discovery more efficient and reliable. In this article, we review computational approaches for allosteric drug discovery and discuss how these tools can be utilized to develop consensus workflows for in silico identification of allosteric sites and modulators with some applications to pathogen resistance and precision medicine. The emerging realization that allosteric modulators can exploit distinct regulatory mechanisms and can provide access to targeted modulation of protein activities could open opportunities for probing biological processes and in silico design of drug combinations with improved therapeutic indices and a broad range of activities.
- Full Text:
- Date Issued: 2020
- Authors: Amamuddy, Olivier S , Veldman, Wade , Manyumwa, Colleen , Khairallah, Afrah , Agajanian, Steve , Oluyemi, Odeyemi , Verkhivker, Gennady M , Tastan Bishop, Özlem
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163012 , vital:41004 , https://doi.org/10.3390/ijms21030847
- Description: Understanding molecular mechanisms underlying the complexity of allosteric regulation in proteins has attracted considerable attention in drug discovery due to the benefits and versatility of allosteric modulators in providing desirable selectivity against protein targets while minimizing toxicity and other side effects. The proliferation of novel computational approaches for predicting ligand–protein interactions and binding using dynamic and network-centric perspectives has led to new insights into allosteric mechanisms and facilitated computer-based discovery of allosteric drugs. Although no absolute method of experimental and in silico allosteric drug/site discovery exists, current methods are still being improved. As such, the critical analysis and integration of established approaches into robust, reproducible, and customizable computational pipelines with experimental feedback could make allosteric drug discovery more efficient and reliable. In this article, we review computational approaches for allosteric drug discovery and discuss how these tools can be utilized to develop consensus workflows for in silico identification of allosteric sites and modulators with some applications to pathogen resistance and precision medicine. The emerging realization that allosteric modulators can exploit distinct regulatory mechanisms and can provide access to targeted modulation of protein activities could open opportunities for probing biological processes and in silico design of drug combinations with improved therapeutic indices and a broad range of activities.
- Full Text:
- Date Issued: 2020
The role of foreign aid in poverty alleviation and economic development in Malawi
- Authors: Amanda, Amerley Armah
- Date: 2019
- Subjects: Economic development
- Language: English
- Type: Thesis , Masters , Degree
- Identifier: http://hdl.handle.net/10948/40220 , vital:35988
- Description: For over fifty years, the majority of the Western nations have provided foreign aid to underdeveloped countries, particularly on the African continent, claiming they wanted to bring about development and alleviate the so-called poverty trap. However, the effect of such financial transfer has not been significant in most of these countries, as many recipient countries still suffer from extreme poverty and underdevelopment. Malawi is a landlocked country found in south-eastern Africa. This small country, despite being a major recipient of foreign aid since the 1960s until the present day, continues to experience extreme poverty. Malawi is one of the world’s poorest countries, ranking 174 out of 187 as at 2013, with over 50.7% of its population living below the poverty line. Thus, this study sought to assess the role of foreign aid in poverty alleviation in Malawi over the years and particularly in the 2000-2015 period. Literature related to this study on foreign aid was reviewed to gain insight into the views of other writers on the topic under study. The study used secondary sources of data to examine the effect of foreign aid on poverty alleviation in Malawi. The study found out that, even though foreign aid to Malawi might have been provided to address poverty and economic challenges to some extent, these objectives have not been met because of donor conditionalities, poor coordination, corruption and mismanagement of donor funding. The study equally found that donors to Malawi over the years have laid much emphasis on good governance rather than poverty alleviation, hence no significant contribution of foreign aid assistance in poverty alleviation, particularly among the rural population which makes up the majority of the poor. This study recommends that to enhance aid effectiveness in poverty alleviation, there is a need for donors to revise their conditions based on the recipient country’s needs and not on donor motives. Secondly, the government of Malawi should consider establishing a legal and legislative framework that guides the use of donor funding and donor activities to ensure accountability and sustainability.
- Full Text:
- Date Issued: 2019
- Authors: Amanda, Amerley Armah
- Date: 2019
- Subjects: Economic development
- Language: English
- Type: Thesis , Masters , Degree
- Identifier: http://hdl.handle.net/10948/40220 , vital:35988
- Description: For over fifty years, the majority of the Western nations have provided foreign aid to underdeveloped countries, particularly on the African continent, claiming they wanted to bring about development and alleviate the so-called poverty trap. However, the effect of such financial transfer has not been significant in most of these countries, as many recipient countries still suffer from extreme poverty and underdevelopment. Malawi is a landlocked country found in south-eastern Africa. This small country, despite being a major recipient of foreign aid since the 1960s until the present day, continues to experience extreme poverty. Malawi is one of the world’s poorest countries, ranking 174 out of 187 as at 2013, with over 50.7% of its population living below the poverty line. Thus, this study sought to assess the role of foreign aid in poverty alleviation in Malawi over the years and particularly in the 2000-2015 period. Literature related to this study on foreign aid was reviewed to gain insight into the views of other writers on the topic under study. The study used secondary sources of data to examine the effect of foreign aid on poverty alleviation in Malawi. The study found out that, even though foreign aid to Malawi might have been provided to address poverty and economic challenges to some extent, these objectives have not been met because of donor conditionalities, poor coordination, corruption and mismanagement of donor funding. The study equally found that donors to Malawi over the years have laid much emphasis on good governance rather than poverty alleviation, hence no significant contribution of foreign aid assistance in poverty alleviation, particularly among the rural population which makes up the majority of the poor. This study recommends that to enhance aid effectiveness in poverty alleviation, there is a need for donors to revise their conditions based on the recipient country’s needs and not on donor motives. Secondly, the government of Malawi should consider establishing a legal and legislative framework that guides the use of donor funding and donor activities to ensure accountability and sustainability.
- Full Text:
- Date Issued: 2019
Discorhabdin N, a South African Natural Compound, for Hsp72 and Hsc70 Allosteric Modulation: combined study of molecular modeling and dynamic residue network analysis
- Amusengeri, Arnold, Tastan Bishop, Özlem
- Authors: Amusengeri, Arnold , Tastan Bishop, Özlem
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/162949 , vital:40999 , https://doi.org/10.3390/molecules24010188
- Description: The human heat shock proteins (Hsps), predominantly Hsp72 and Hsp90, have been strongly implicated in various critical stages of oncogenesis and progression of human cancers. While drug development has extensively focused on Hsp90 as a potential anticancer target, much less effort has been put against Hsp72. This work investigated the therapeutic potential of Hsp72 and its constitutive isoform, Hsc70, via in silico-based screening against the South African Natural Compounds Database (SANCDB). A comparative modeling approach was used to obtain nearly full-length 3D structures of the closed conformation of Hsp72 and Hsc70 proteins. Molecular docking of SANCDB compounds identified one potential allosteric modulator, Discorhabdin N, binding to the allosteric β substrate binding domain (SBDβ) back pocket, with good binding affinities in both cases.
- Full Text:
- Date Issued: 2019
- Authors: Amusengeri, Arnold , Tastan Bishop, Özlem
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/162949 , vital:40999 , https://doi.org/10.3390/molecules24010188
- Description: The human heat shock proteins (Hsps), predominantly Hsp72 and Hsp90, have been strongly implicated in various critical stages of oncogenesis and progression of human cancers. While drug development has extensively focused on Hsp90 as a potential anticancer target, much less effort has been put against Hsp72. This work investigated the therapeutic potential of Hsp72 and its constitutive isoform, Hsc70, via in silico-based screening against the South African Natural Compounds Database (SANCDB). A comparative modeling approach was used to obtain nearly full-length 3D structures of the closed conformation of Hsp72 and Hsc70 proteins. Molecular docking of SANCDB compounds identified one potential allosteric modulator, Discorhabdin N, binding to the allosteric β substrate binding domain (SBDβ) back pocket, with good binding affinities in both cases.
- Full Text:
- Date Issued: 2019
Establishing computational approaches towards identifying malarial allosteric modulators: a case study of plasmodium falciparum hsp70s
- Amusengeri, Arnold, Astl, Lindy, Lobb, Kevin A, Verkhivker, Gennady M, Tastan Bishop, Özlem
- Authors: Amusengeri, Arnold , Astl, Lindy , Lobb, Kevin A , Verkhivker, Gennady M , Tastan Bishop, Özlem
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163000 , vital:41003 , https://doi.org/10.3390/ijms20225574
- Description: Combating malaria is almost a never-ending battle, as Plasmodium parasites develop resistance to the drugs used against them, as observed recently in artemisinin-based combination therapies. The main concern now is if the resistant parasite strains spread from Southeast Asia to Africa, the continent hosting most malaria cases. To prevent catastrophic results, we need to find non-conventional approaches. Allosteric drug targeting sites and modulators might be a new hope for malarial treatments. Heat shock proteins (HSPs) are potential malarial drug targets and have complex allosteric control mechanisms. Yet, studies on designing allosteric modulators against them are limited. Here, we identified allosteric modulators (SANC190 and SANC651) against P. falciparum Hsp70-1 and Hsp70-x, affecting the conformational dynamics of the proteins, delicately balanced by the endogenous ligands. Previously, we established a pipeline to identify allosteric sites and modulators. This study also further investigated alternative approaches to speed up the process by comparing all atom molecular dynamics simulations and dynamic residue network analysis with the coarse-grained (CG) versions of the calculations. Betweenness centrality (BC) profiles for PfHsp70-1 and PfHsp70-x derived from CG simulations not only revealed similar trends but also pointed to the same functional regions and specific residues corresponding to BC profile peaks.
- Full Text:
- Date Issued: 2019
- Authors: Amusengeri, Arnold , Astl, Lindy , Lobb, Kevin A , Verkhivker, Gennady M , Tastan Bishop, Özlem
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163000 , vital:41003 , https://doi.org/10.3390/ijms20225574
- Description: Combating malaria is almost a never-ending battle, as Plasmodium parasites develop resistance to the drugs used against them, as observed recently in artemisinin-based combination therapies. The main concern now is if the resistant parasite strains spread from Southeast Asia to Africa, the continent hosting most malaria cases. To prevent catastrophic results, we need to find non-conventional approaches. Allosteric drug targeting sites and modulators might be a new hope for malarial treatments. Heat shock proteins (HSPs) are potential malarial drug targets and have complex allosteric control mechanisms. Yet, studies on designing allosteric modulators against them are limited. Here, we identified allosteric modulators (SANC190 and SANC651) against P. falciparum Hsp70-1 and Hsp70-x, affecting the conformational dynamics of the proteins, delicately balanced by the endogenous ligands. Previously, we established a pipeline to identify allosteric sites and modulators. This study also further investigated alternative approaches to speed up the process by comparing all atom molecular dynamics simulations and dynamic residue network analysis with the coarse-grained (CG) versions of the calculations. Betweenness centrality (BC) profiles for PfHsp70-1 and PfHsp70-x derived from CG simulations not only revealed similar trends but also pointed to the same functional regions and specific residues corresponding to BC profile peaks.
- Full Text:
- Date Issued: 2019
Understanding the Pyrimethamine drug resistance mechanism via combined molecular dynamics and dynamic residue network analysis:
- Amusengeri, Arnold, Tata, Rolland B, Tastan Bishop, Özlem
- Authors: Amusengeri, Arnold , Tata, Rolland B , Tastan Bishop, Özlem
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163022 , vital:41005 , https://doi.org/10.3390/molecules25040904
- Description: In this era of precision medicine, insights into the resistance mechanism of drugs are integral for the development of potent therapeutics. Here, we sought to understand the contribution of four point mutations (N51I, C59R, S108N, and I164L) within the active site of the malaria parasite enzyme dihydrofolate reductase (DHFR) towards the resistance of the antimalarial drug pyrimethamine. Homology modeling was used to obtain full-length models of wild type (WT) and mutant DHFR. Molecular docking was employed to dock pyrimethamine onto the generated structures. Subsequent all-atom molecular dynamics (MD) simulations and binding free-energy computations highlighted that pyrimethamine’s stability and affinity inversely relates to the number of mutations within its binding site and, hence, resistance severity.
- Full Text:
- Date Issued: 2020
- Authors: Amusengeri, Arnold , Tata, Rolland B , Tastan Bishop, Özlem
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163022 , vital:41005 , https://doi.org/10.3390/molecules25040904
- Description: In this era of precision medicine, insights into the resistance mechanism of drugs are integral for the development of potent therapeutics. Here, we sought to understand the contribution of four point mutations (N51I, C59R, S108N, and I164L) within the active site of the malaria parasite enzyme dihydrofolate reductase (DHFR) towards the resistance of the antimalarial drug pyrimethamine. Homology modeling was used to obtain full-length models of wild type (WT) and mutant DHFR. Molecular docking was employed to dock pyrimethamine onto the generated structures. Subsequent all-atom molecular dynamics (MD) simulations and binding free-energy computations highlighted that pyrimethamine’s stability and affinity inversely relates to the number of mutations within its binding site and, hence, resistance severity.
- Full Text:
- Date Issued: 2020
Financial inclusion and economic growth in Ghana
- Authors: Anane, Alexander Kwabena
- Date: 2019
- Subjects: Economic development -- Ghana
- Language: English
- Type: Thesis , Masters , MPhil
- Identifier: http://hdl.handle.net/10948/40210 , vital:35990
- Description: The relationship between financial inclusion and the growth of the economy is a topic of debate in the existing literature. Yet globally and at individual country level, policy makers have accepted financial inclusion as a developmental agenda. This study, therefore, empirically investigates the relationship between financial inclusion and economic growth in Ghana using quarterly time series data from 2005 to 2016. Employing the commonly used indicators, the ARDL bounds test with cointergration was applied to examine the short and the long run relationship between the variables. Furthermore, the Granger causality approach was also used to establish the direction between financial inclusion and economic growth in Ghana. The result of the findings confirmed mixed results and no clear cut relationship between the direction of causality between the indicators of financial inclusion and economic growth. The study concluded that whether financial inclusion positively or negatively impact economic growth rests on the indicators employed. The study therefore cautions in the choice of financial indicators as policy tools in designing and executing economic growth and development policies in Ghana.
- Full Text:
- Date Issued: 2019
- Authors: Anane, Alexander Kwabena
- Date: 2019
- Subjects: Economic development -- Ghana
- Language: English
- Type: Thesis , Masters , MPhil
- Identifier: http://hdl.handle.net/10948/40210 , vital:35990
- Description: The relationship between financial inclusion and the growth of the economy is a topic of debate in the existing literature. Yet globally and at individual country level, policy makers have accepted financial inclusion as a developmental agenda. This study, therefore, empirically investigates the relationship between financial inclusion and economic growth in Ghana using quarterly time series data from 2005 to 2016. Employing the commonly used indicators, the ARDL bounds test with cointergration was applied to examine the short and the long run relationship between the variables. Furthermore, the Granger causality approach was also used to establish the direction between financial inclusion and economic growth in Ghana. The result of the findings confirmed mixed results and no clear cut relationship between the direction of causality between the indicators of financial inclusion and economic growth. The study concluded that whether financial inclusion positively or negatively impact economic growth rests on the indicators employed. The study therefore cautions in the choice of financial indicators as policy tools in designing and executing economic growth and development policies in Ghana.
- Full Text:
- Date Issued: 2019
The evolution of the Lepilemuridae-Cheirogaleidae clade
- Authors: Andrews, Curswan Allan
- Date: 2019
- Subjects: Lemurs
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/40216 , vital:35989
- Description: The Lepilemuridae and the Cheirogaleidae, according to recent molecular reconstructions, share a more recent common ancestor than previously thought. Further phylogenetic reconstructions have indicated that body size evolution in this clade was marked by repeated dwarfing events that coincided with changes in the environment. I aimed to investigate the morphological implications of changes in body size within the Lepilemur-cheirogaleid clade, testing four predictions. Together with Dr. Couette, I collected data on the overall palate shape and predicted that shape is likely to be influenced by several factors including phylogeny, body size and diet. Geometric morphometric analyses revealed that, although a strong phylogenetic signal was detected, diet had the major effect on palate shape. In a similar vein, when examining the arterial circulation patterns in these taxa, I predicted that changes in body size would result in changes and possible reductions in arterial size, particularly the internal carotid artery (ICA) and stapedial artery (SA). Analyses with micro-computed tomography (CT) and 3D imaging indicated that changes in body size led to reduction of a functional stapedial artery in Lepilemur, making it an intermediate stage between the daubentoniid, lemurid and indriid species with large stapedial arteries, and the smaller bodied cheirogaleids with an alternative blood supply in the form of an enlarged ascending pharyngeal artery. Lepilemur is the smallest living folivorous primate, and likely to be at the threshold body size to be able to subsist on such a poor diet. To investigate shifts in dietary patterns that accompanied changes in body size, I chose to explore the reported behaviour of caecotrophy as a possible means for the sportive lemurs to derive additional nutrient from their food sources. I predicted that, if caecotrophy is a way to assist folivory at small body size, the energy contained in “caecotrophic” and latrine faecal samples should be different. Analyses showed significant iv differences between the two types of faeces and, combined with an analysis of faecal bacterial diversity, support the occurrence of caecotrophy. Finally, I compared the digestive efficiency of two small, distantly related gummivorous primates that evolved their diets convergently. I studied the digestion of gum in Microcebus griseorufus and compared this with gum digestion in Galago moholi. I predicted that an evolutionary disposition to fermentation inherited from a folivorous ancestor would aid in the digestion of gum in mouse lemurs. Results indicated that retention time was prolonged by the presence of secondary compounds in Microcebus fed with Commiphora gum but relatively shorter (< 24 hrs) when fed Alantsilodenron gum, a preferred food. Despite the fact that G. moholi has an ansa coli, which is missing in M. griseorufus species, both are highly efficient at digesting gum. These data provide some of the first indicators of how dietary changes from a larger-bodied folivorous ancestor to partially gummivorous, small-bodied descendants may have occurred in evolutionary time.
- Full Text:
- Date Issued: 2019
- Authors: Andrews, Curswan Allan
- Date: 2019
- Subjects: Lemurs
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/40216 , vital:35989
- Description: The Lepilemuridae and the Cheirogaleidae, according to recent molecular reconstructions, share a more recent common ancestor than previously thought. Further phylogenetic reconstructions have indicated that body size evolution in this clade was marked by repeated dwarfing events that coincided with changes in the environment. I aimed to investigate the morphological implications of changes in body size within the Lepilemur-cheirogaleid clade, testing four predictions. Together with Dr. Couette, I collected data on the overall palate shape and predicted that shape is likely to be influenced by several factors including phylogeny, body size and diet. Geometric morphometric analyses revealed that, although a strong phylogenetic signal was detected, diet had the major effect on palate shape. In a similar vein, when examining the arterial circulation patterns in these taxa, I predicted that changes in body size would result in changes and possible reductions in arterial size, particularly the internal carotid artery (ICA) and stapedial artery (SA). Analyses with micro-computed tomography (CT) and 3D imaging indicated that changes in body size led to reduction of a functional stapedial artery in Lepilemur, making it an intermediate stage between the daubentoniid, lemurid and indriid species with large stapedial arteries, and the smaller bodied cheirogaleids with an alternative blood supply in the form of an enlarged ascending pharyngeal artery. Lepilemur is the smallest living folivorous primate, and likely to be at the threshold body size to be able to subsist on such a poor diet. To investigate shifts in dietary patterns that accompanied changes in body size, I chose to explore the reported behaviour of caecotrophy as a possible means for the sportive lemurs to derive additional nutrient from their food sources. I predicted that, if caecotrophy is a way to assist folivory at small body size, the energy contained in “caecotrophic” and latrine faecal samples should be different. Analyses showed significant iv differences between the two types of faeces and, combined with an analysis of faecal bacterial diversity, support the occurrence of caecotrophy. Finally, I compared the digestive efficiency of two small, distantly related gummivorous primates that evolved their diets convergently. I studied the digestion of gum in Microcebus griseorufus and compared this with gum digestion in Galago moholi. I predicted that an evolutionary disposition to fermentation inherited from a folivorous ancestor would aid in the digestion of gum in mouse lemurs. Results indicated that retention time was prolonged by the presence of secondary compounds in Microcebus fed with Commiphora gum but relatively shorter (< 24 hrs) when fed Alantsilodenron gum, a preferred food. Despite the fact that G. moholi has an ansa coli, which is missing in M. griseorufus species, both are highly efficient at digesting gum. These data provide some of the first indicators of how dietary changes from a larger-bodied folivorous ancestor to partially gummivorous, small-bodied descendants may have occurred in evolutionary time.
- Full Text:
- Date Issued: 2019
The development of sustainability ratios for public listed companies
- Authors: Anywar, Apio Dorcas
- Date: 2019
- Subjects: Business enterprises -- Finance
- Language: English
- Type: Thesis , Doctoral , DBA
- Identifier: http://hdl.handle.net/10948/40229 , vital:35991
- Description: Financial analysis is important when assessing a business’ financial as well as economic performance, and ratios are among the best known and most widely - used tools for financial analysis. Ratios act as a benchmarking and trend analysis tool by disclosing relationships as well as bases of comparison that reveal conditions and trends that cannot be detected by the individual components of the ratio. In addition, there is a need to measure sustainability performance as sustainability aims to radically transform how businesses understand and create value. Measuring sustainability performance can determine whether a business is moving in the right direction. This study developed a proposed set of sustainability ratios that could be used to determine the efficient and effective sustainability performance of public listed companies in South Africa. The study used a mixed methods research approach in three phases consisting of ten steps. In Phase 1 (Step 1), a secondary research in the form of a literature review was conducted. The critically evaluated secondary literature sources were used to create a theoretical framework of sustainability ratios and a ‘schedule for content analyses. In Phase 2 (Steps 2, 3, 4, 5), a quantitative content analysis of sustainability reports of FTSE/JSE Responsible Investment Top 30 Index companies was performed to obtain the variables that were used to calculate the sustainability ratios in the theoretical framework. It also identified additional sustainability ratios that were used by companies in practice, but that were not included in the theoretical framework of sustainability ratios. The sustainability ratios from the theoretical framework were calculated using the variables collected from the sustainability reports. Thereafter, descriptive statistical techniques were used to analyse the results. Lastly, in Phase 3 (Steps 6, 7, 8, 9), qualitative criteria were used to test the variables for the sustainability ratios that could not be calculated and to select the ratios from those calculated, reported and tested to be included in the proposed set of sustainability ratios. The purpose of Phase 3 was to test the usability, relevance, measurability, understandability and comparability of the sustainability ratios proposed in the theoretical framework as well as the sustainability ratios that were applied in the content of sustainability reports in South Africa. Step 10 represented the outcome of the study, a set of sustainability ratios was proposed. A set of 101 sustainability ratios were proposed. The proposed set of sustainability ratios linked the different sustainability issues to financial results by classifying them into four main categories, namely, (i) sustainable operational efficiency and effectiveness ratios (SOEE), (ii) sustainable risk - minimisation ratios (SRM), (iii) sustainable reputation – brand value ratios (SRBV) and (iv) sustainable innovation ratios (SI). These sustainability ratios could be used to assess the efficiency and effectiveness of a business’ sustainability strategies, its risk minimisation strategies, innovative capacities and reputation as well as brand value enhancing strategies. As the concern for business sustainability increases, the proposed sustainability ratios might satisfy the concerns of customers and stakeholders. These proposed ratios could also be refined in the future.
- Full Text:
- Date Issued: 2019
- Authors: Anywar, Apio Dorcas
- Date: 2019
- Subjects: Business enterprises -- Finance
- Language: English
- Type: Thesis , Doctoral , DBA
- Identifier: http://hdl.handle.net/10948/40229 , vital:35991
- Description: Financial analysis is important when assessing a business’ financial as well as economic performance, and ratios are among the best known and most widely - used tools for financial analysis. Ratios act as a benchmarking and trend analysis tool by disclosing relationships as well as bases of comparison that reveal conditions and trends that cannot be detected by the individual components of the ratio. In addition, there is a need to measure sustainability performance as sustainability aims to radically transform how businesses understand and create value. Measuring sustainability performance can determine whether a business is moving in the right direction. This study developed a proposed set of sustainability ratios that could be used to determine the efficient and effective sustainability performance of public listed companies in South Africa. The study used a mixed methods research approach in three phases consisting of ten steps. In Phase 1 (Step 1), a secondary research in the form of a literature review was conducted. The critically evaluated secondary literature sources were used to create a theoretical framework of sustainability ratios and a ‘schedule for content analyses. In Phase 2 (Steps 2, 3, 4, 5), a quantitative content analysis of sustainability reports of FTSE/JSE Responsible Investment Top 30 Index companies was performed to obtain the variables that were used to calculate the sustainability ratios in the theoretical framework. It also identified additional sustainability ratios that were used by companies in practice, but that were not included in the theoretical framework of sustainability ratios. The sustainability ratios from the theoretical framework were calculated using the variables collected from the sustainability reports. Thereafter, descriptive statistical techniques were used to analyse the results. Lastly, in Phase 3 (Steps 6, 7, 8, 9), qualitative criteria were used to test the variables for the sustainability ratios that could not be calculated and to select the ratios from those calculated, reported and tested to be included in the proposed set of sustainability ratios. The purpose of Phase 3 was to test the usability, relevance, measurability, understandability and comparability of the sustainability ratios proposed in the theoretical framework as well as the sustainability ratios that were applied in the content of sustainability reports in South Africa. Step 10 represented the outcome of the study, a set of sustainability ratios was proposed. A set of 101 sustainability ratios were proposed. The proposed set of sustainability ratios linked the different sustainability issues to financial results by classifying them into four main categories, namely, (i) sustainable operational efficiency and effectiveness ratios (SOEE), (ii) sustainable risk - minimisation ratios (SRM), (iii) sustainable reputation – brand value ratios (SRBV) and (iv) sustainable innovation ratios (SI). These sustainability ratios could be used to assess the efficiency and effectiveness of a business’ sustainability strategies, its risk minimisation strategies, innovative capacities and reputation as well as brand value enhancing strategies. As the concern for business sustainability increases, the proposed sustainability ratios might satisfy the concerns of customers and stakeholders. These proposed ratios could also be refined in the future.
- Full Text:
- Date Issued: 2019
Testing the efficient market hypothesis in the cryptocurrency market
- Authors: Apopo, Natalya Camilla
- Date: 2019
- Subjects: Digital currency
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10948/42427 , vital:36662
- Description: Digital currencies are rising in popularity owing to their purported benefits and the speculative profits that investors are making in the market. These currencies, though decentralised in substance, can be purchased using digital wallets from cryptocurrency exchange platforms around the world. In Africa, these platforms are still at the nascent stages of growth and development, but evidence suggests a burgeoning potential in these markets. Volatility in these markets has been a topic of concern for many empirical investigations with most finding corroborative evidence of excess volatility in the digital currency market. However, there is a conflicting body of evidence when it comes to the studies evaluating the efficiency of the virtual currency market. The efficient market hypothesis ( EMH)is a controversial theory in finance. Proponents argue that it provides a basis for understanding financial markets whereas opponents suggest that the hypothesis is premature in its assumptions of the real functioning of these markets. Though not perfect, the efficient markets model provides a sufficient baseline against which capital markets may be analysed. Besides being one of the most empirically investigated theories in finance, its utility led to the development of later models such as the capital asset pricing model. In postulating that the prices of securities reflect all available information in capital markets, the efficient markets theory lends itself to testing the efficacy levels of the cryptocurrency market. For the purposes of this study, the weak version of the efficient markets theory was evaluated as itis considered the lowest possible form of efficiency attainable. Using both linear and nonlinear unit root testing methodologies, a significant subset of the cryptocurrency market was investigated for inefficiencies via the null hypothesis of non-stationarity. There were mixed results from the testing process, but a substantial portion of the currencies investigated rejected the null of a unit root in favour of stationarity, providing some evidence against weak form efficiency. For these reasons, it is recommended that further research be conducted in the virtual currency markets to offer more conclusive findings.
- Full Text:
- Date Issued: 2019
- Authors: Apopo, Natalya Camilla
- Date: 2019
- Subjects: Digital currency
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10948/42427 , vital:36662
- Description: Digital currencies are rising in popularity owing to their purported benefits and the speculative profits that investors are making in the market. These currencies, though decentralised in substance, can be purchased using digital wallets from cryptocurrency exchange platforms around the world. In Africa, these platforms are still at the nascent stages of growth and development, but evidence suggests a burgeoning potential in these markets. Volatility in these markets has been a topic of concern for many empirical investigations with most finding corroborative evidence of excess volatility in the digital currency market. However, there is a conflicting body of evidence when it comes to the studies evaluating the efficiency of the virtual currency market. The efficient market hypothesis ( EMH)is a controversial theory in finance. Proponents argue that it provides a basis for understanding financial markets whereas opponents suggest that the hypothesis is premature in its assumptions of the real functioning of these markets. Though not perfect, the efficient markets model provides a sufficient baseline against which capital markets may be analysed. Besides being one of the most empirically investigated theories in finance, its utility led to the development of later models such as the capital asset pricing model. In postulating that the prices of securities reflect all available information in capital markets, the efficient markets theory lends itself to testing the efficacy levels of the cryptocurrency market. For the purposes of this study, the weak version of the efficient markets theory was evaluated as itis considered the lowest possible form of efficiency attainable. Using both linear and nonlinear unit root testing methodologies, a significant subset of the cryptocurrency market was investigated for inefficiencies via the null hypothesis of non-stationarity. There were mixed results from the testing process, but a substantial portion of the currencies investigated rejected the null of a unit root in favour of stationarity, providing some evidence against weak form efficiency. For these reasons, it is recommended that further research be conducted in the virtual currency markets to offer more conclusive findings.
- Full Text:
- Date Issued: 2019
Factors influencing parents’ decisions when choosing a private school
- Authors: Arendse, David
- Date: 2019
- Subjects: School choice -- South Africa -- Case studies , Competition -- South Africa , Private schools -- South Africa , Consumer behavior , VRIO framework (Valuable, Rare, Imitable and Organized) , St. Stithians College
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/92628 , vital:30738
- Description: Purpose: Consumers make decisions based on multiple factors that influence their decision-making process. These decisions can be influenced by deep personal reflection to the simple impulsive purchase done to fulfil a need or want. This research study explored the relationship between the resource-based view and the factors considered by parents when selecting a school for their child/children. The Valuable, Rare, Imitable and Organized (VRIO) framework as developed by Barney, J. (1991) outlines the framework through which an organisations resources can be assessed in terms of their potential competitive advantage. The research study was interested in understanding how an educational institution can identify and then leverage its resources to create a competitive advantage. Methodology: Each family that has one or more child enrolled at St Stithians College, which is a private school in Gauteng, South Africa, was invited to participate in the study. This represented a potential population size of 1 700 families, however a sample of 334 was used. The educational institution caters to both boys and girls from Grade R to 12 (Matric). Each family was requested to participate in the study as they had already chosen to have at least one child enrolled. A self-administered close-ended questionnaire was used as the instrument for data collection and the questionnaire was broken into two sections. Section A focused on building a profile of the respondent while section B assessed the level of influence the factors had on a parent’s decision. Section B’s questions were structured as Likert-Scale questions requiring a response between 1 and 5, with 5 being the highest influence, and 1 being the lowest. The responses to the questions were then grouped into the factors they spoke to and the average results per factor were assessed via an ANOVA table to test the null hypothesis that parents do not consider factors when choosing a school for their children. Findings: As a paper, this study set out to discover what the competitive advantage was of a private education institution in South Africa. It did so by identifying what the key factors were when parents selected the school of their choice and then analysed these findings against the resources of the given institution. The ANOVA table analysis of the responses identified that parents do consider factors and that the factor that they were most influenced by was convenience factor, represented by location of the institution and the distance to it. While there are multiple private education suppliers in South Africa, no other provider has the location that St Stithians College has, and as such, its location is its competitive advantage. Significant: This research study will expand the existing but limited competitive advantage body of knowledge in the South African education sector. South African educational institutions will be able to develop similar studies which will then assist in identifying their own competitive advantages. This can better enable education providers to entice consumers to their education services.
- Full Text:
- Date Issued: 2019
- Authors: Arendse, David
- Date: 2019
- Subjects: School choice -- South Africa -- Case studies , Competition -- South Africa , Private schools -- South Africa , Consumer behavior , VRIO framework (Valuable, Rare, Imitable and Organized) , St. Stithians College
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/92628 , vital:30738
- Description: Purpose: Consumers make decisions based on multiple factors that influence their decision-making process. These decisions can be influenced by deep personal reflection to the simple impulsive purchase done to fulfil a need or want. This research study explored the relationship between the resource-based view and the factors considered by parents when selecting a school for their child/children. The Valuable, Rare, Imitable and Organized (VRIO) framework as developed by Barney, J. (1991) outlines the framework through which an organisations resources can be assessed in terms of their potential competitive advantage. The research study was interested in understanding how an educational institution can identify and then leverage its resources to create a competitive advantage. Methodology: Each family that has one or more child enrolled at St Stithians College, which is a private school in Gauteng, South Africa, was invited to participate in the study. This represented a potential population size of 1 700 families, however a sample of 334 was used. The educational institution caters to both boys and girls from Grade R to 12 (Matric). Each family was requested to participate in the study as they had already chosen to have at least one child enrolled. A self-administered close-ended questionnaire was used as the instrument for data collection and the questionnaire was broken into two sections. Section A focused on building a profile of the respondent while section B assessed the level of influence the factors had on a parent’s decision. Section B’s questions were structured as Likert-Scale questions requiring a response between 1 and 5, with 5 being the highest influence, and 1 being the lowest. The responses to the questions were then grouped into the factors they spoke to and the average results per factor were assessed via an ANOVA table to test the null hypothesis that parents do not consider factors when choosing a school for their children. Findings: As a paper, this study set out to discover what the competitive advantage was of a private education institution in South Africa. It did so by identifying what the key factors were when parents selected the school of their choice and then analysed these findings against the resources of the given institution. The ANOVA table analysis of the responses identified that parents do consider factors and that the factor that they were most influenced by was convenience factor, represented by location of the institution and the distance to it. While there are multiple private education suppliers in South Africa, no other provider has the location that St Stithians College has, and as such, its location is its competitive advantage. Significant: This research study will expand the existing but limited competitive advantage body of knowledge in the South African education sector. South African educational institutions will be able to develop similar studies which will then assist in identifying their own competitive advantages. This can better enable education providers to entice consumers to their education services.
- Full Text:
- Date Issued: 2019
Checklist, endemism, English vernacular names and identification of the cicadas (Insecta, Hemiptera, Cicadidae) of KwaZulu-Natal, South Africa:
- Armstrong, Adrian J, Villet, Martin H
- Authors: Armstrong, Adrian J , Villet, Martin H
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140586 , vital:37901 , DOI: 10.3897/afrinvertebr.60.35130
- Description: Public understanding of the goals of applied biology and conservation is promoted by showcasing charismatic or significant organisms using vernacular names. Conservation activities in the province of KwaZulu-Natal, South Africa, are prioritising taxa that have high rates of provincial endemism, such as snails, earthworms, millipedes and cicadas. To assist wider public engagement in these activities, an assessment of endemism of the cicadas of KwaZulu-Natal is presented along with a dichotomous, 37-couplet key for the identification of males, based mainly on externally visible morphology and colouration. Standardised English vernacular names coined following a simple naming convention are proposed. Forty-two percent (16 out of 38) of the cicada species known from KwaZulu-Natal are endemic to the province. Photographs of some of the species are included to facilitate their identification. Photographs can be used for identification of various species providing that the diagnostic characters are visible in the photographs. For this purpose, photographs may have to be taken of hand-held individuals. Some of the endemic species are of particular concern for conservation because they are not known to occur in statutory protected areas or are only known from relatively small protected areas. The latter may not be able to ensure the long-term survival of the species. The rate and extent of loss of habitat outside protected areas is likely to be a grave threat to species that are not protected or that are inadequately conserved in statutory protected areas. The standardised vernacular names proposed here provide a tool for communicating provincial conservation plans and concerns with stakeholders in KwaZulu-Natal and for stimulating interest in cicadas amongst land users, environmental impact assessment practitioners, biologists, naturalists and citizen scientists.
- Full Text:
- Date Issued: 2019
- Authors: Armstrong, Adrian J , Villet, Martin H
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140586 , vital:37901 , DOI: 10.3897/afrinvertebr.60.35130
- Description: Public understanding of the goals of applied biology and conservation is promoted by showcasing charismatic or significant organisms using vernacular names. Conservation activities in the province of KwaZulu-Natal, South Africa, are prioritising taxa that have high rates of provincial endemism, such as snails, earthworms, millipedes and cicadas. To assist wider public engagement in these activities, an assessment of endemism of the cicadas of KwaZulu-Natal is presented along with a dichotomous, 37-couplet key for the identification of males, based mainly on externally visible morphology and colouration. Standardised English vernacular names coined following a simple naming convention are proposed. Forty-two percent (16 out of 38) of the cicada species known from KwaZulu-Natal are endemic to the province. Photographs of some of the species are included to facilitate their identification. Photographs can be used for identification of various species providing that the diagnostic characters are visible in the photographs. For this purpose, photographs may have to be taken of hand-held individuals. Some of the endemic species are of particular concern for conservation because they are not known to occur in statutory protected areas or are only known from relatively small protected areas. The latter may not be able to ensure the long-term survival of the species. The rate and extent of loss of habitat outside protected areas is likely to be a grave threat to species that are not protected or that are inadequately conserved in statutory protected areas. The standardised vernacular names proposed here provide a tool for communicating provincial conservation plans and concerns with stakeholders in KwaZulu-Natal and for stimulating interest in cicadas amongst land users, environmental impact assessment practitioners, biologists, naturalists and citizen scientists.
- Full Text:
- Date Issued: 2019