Award from the Women's Development Foundation, 2010
- Date: 2022 , 2022-09-23
- Subjects: Bam, Brigalia , Bam, Brigalia -- Awards
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56595 , vital:56867
- Description: Dr. Brigalia Bam received an award from The Women's Development Foundation in 2010 for repositioning the Foundation. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-23
- Subjects: Bam, Brigalia , Bam, Brigalia -- Awards
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56595 , vital:56867
- Description: Dr. Brigalia Bam received an award from The Women's Development Foundation in 2010 for repositioning the Foundation. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Backpack carriage and musculoskeletal pain among primary school learners in King Williams Town, South Africa
- Authors: Moni, Busisiwe
- Date: 2022
- Subjects: Backache -- Prevention , Pediatric rheumatology , Pain -- Treatment
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26984 , vital:66208
- Description: BACKGROUND: There is rising concern that kids are walking to school with too much weight on their backs. The weight of schoolchildren's backpacks is a persistent and divisive topic in the fields of education and health. Children who carry heavy backpacks are more likely to have back discomfort and musculoskeletal pain, which raises their risk of developing chronic back pain as adults. There is little research on this topic among South African school-age youngsters. The goal of the study was to find out how common low back and other musculoskeletal complaints were among primary school students who used a school bag. RESEARCH AIM: The purpose of the study was to identify the prevalence and location of musculoskeletal discomfort in primary school students in King William's Town, South Africa, and describe their link with backpack use. METHOD: In King Williams Town, Eastern Cape, South Africa, a descriptive cross-sectional survey was conducted among elementary school students between the ages of 9 and 14 years old. A systematic questionnaire and the Cornell Musculoskeletal Questionnaire were used to gather the data (body chart). Age, gender, and schoolbag details (style of backpack, carrying technique, and carrying time) were collected. The learner's waist, hip, and bag circumferences were all measured. On the data, descriptive and interferential statistics were used. FINDINGS: The study's conclusions showed that students' musculoskeletal pain was brought on by the weight of their backpacks or school bags. The majority of the students (89.8percent) complain about the difficulty they experience when lugging their heavy backpacks to class. In addition, 83.4percent of the students had bags that weighed more than 10percent of their body weight. Additionally, a sizable percentage of students (89.8percent) carry a hefty bag to school every day and report feeling fatigued while doing so (90.8percent). 90percent of the students reported feeling discomfort before, during, or after carrying their schoolbags. This pain is related with carrying a schoolbag. The majority of students (53.5percent) felt that their daily pain interferes with their ability to study. In order of severity, the majority of students report having discomfort in their shoulders (82.7percent), lower back (59.9percent), neck (47.0percent), upper back (40.7percent), and upper arm (16.4percent). CONCLUSION: According to the study, there is a link between students' musculoskeletal pain and carrying hefty backpacks or school bags. The shoulders are where musculoskeletal discomfort is most frequently felt. The study supported the findings of the majority of studies cited in the literature that most schoolchildren suffer from musculoskeletal pain because the weight of their backpacks is excessive compared to their size, weight, and age. RECOMMENDATIONS: The study produced a number of recommendations, including that the Department of Basic Education inform teachers, students, parents, guardians, and other key stakeholders about the effects of heavy backpacks or schoolbags on students' musculoskeletal pain. For students' convenience and to lighten the load on their school bags, locker rooms should be available. Teachers, parents, and guardians should also pay attention to the school bags that students are using to make sure that the weight is appropriate for their age and body size. , Thesis (MPA) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022
- Authors: Moni, Busisiwe
- Date: 2022
- Subjects: Backache -- Prevention , Pediatric rheumatology , Pain -- Treatment
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26984 , vital:66208
- Description: BACKGROUND: There is rising concern that kids are walking to school with too much weight on their backs. The weight of schoolchildren's backpacks is a persistent and divisive topic in the fields of education and health. Children who carry heavy backpacks are more likely to have back discomfort and musculoskeletal pain, which raises their risk of developing chronic back pain as adults. There is little research on this topic among South African school-age youngsters. The goal of the study was to find out how common low back and other musculoskeletal complaints were among primary school students who used a school bag. RESEARCH AIM: The purpose of the study was to identify the prevalence and location of musculoskeletal discomfort in primary school students in King William's Town, South Africa, and describe their link with backpack use. METHOD: In King Williams Town, Eastern Cape, South Africa, a descriptive cross-sectional survey was conducted among elementary school students between the ages of 9 and 14 years old. A systematic questionnaire and the Cornell Musculoskeletal Questionnaire were used to gather the data (body chart). Age, gender, and schoolbag details (style of backpack, carrying technique, and carrying time) were collected. The learner's waist, hip, and bag circumferences were all measured. On the data, descriptive and interferential statistics were used. FINDINGS: The study's conclusions showed that students' musculoskeletal pain was brought on by the weight of their backpacks or school bags. The majority of the students (89.8percent) complain about the difficulty they experience when lugging their heavy backpacks to class. In addition, 83.4percent of the students had bags that weighed more than 10percent of their body weight. Additionally, a sizable percentage of students (89.8percent) carry a hefty bag to school every day and report feeling fatigued while doing so (90.8percent). 90percent of the students reported feeling discomfort before, during, or after carrying their schoolbags. This pain is related with carrying a schoolbag. The majority of students (53.5percent) felt that their daily pain interferes with their ability to study. In order of severity, the majority of students report having discomfort in their shoulders (82.7percent), lower back (59.9percent), neck (47.0percent), upper back (40.7percent), and upper arm (16.4percent). CONCLUSION: According to the study, there is a link between students' musculoskeletal pain and carrying hefty backpacks or school bags. The shoulders are where musculoskeletal discomfort is most frequently felt. The study supported the findings of the majority of studies cited in the literature that most schoolchildren suffer from musculoskeletal pain because the weight of their backpacks is excessive compared to their size, weight, and age. RECOMMENDATIONS: The study produced a number of recommendations, including that the Department of Basic Education inform teachers, students, parents, guardians, and other key stakeholders about the effects of heavy backpacks or schoolbags on students' musculoskeletal pain. For students' convenience and to lighten the load on their school bags, locker rooms should be available. Teachers, parents, and guardians should also pay attention to the school bags that students are using to make sure that the weight is appropriate for their age and body size. , Thesis (MPA) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022
Best of both worlds: The thermal physiology of Hydrellia egeriae, a biological control agent for the submerged aquatic weed, Egeria densa in South Africa
- Smith, Rosali, Coetzee, Julie A, Hill, Martin P
- Authors: Smith, Rosali , Coetzee, Julie A , Hill, Martin P
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/417913 , vital:71494 , xlink:href="https://doi.org/10.1007/s10526-022-10142-w"
- Description: The submerged aquatic weed, Egeria densa Planch. (Hydrocharitaceae) or Brazilian waterweed, is a secondary invader of eutrophic freshwater systems in South Africa, following the successful management of floating aquatic weeds. In 2018, the leaf and stem-mining fly, Hydrellia egeriae Rodrigues-Júnior, Mathis and Hauser (Diptera: Ephydridae), was released against E. densa, the first agent released against a submerged aquatic weed in South Africa. During its life stages, the biological control agent is exposed to two environments, air and water. The thermal physiology of both life stages was investigated to optimize agent establishment through fine-tuned release strategies. The thermal physiological limits of H. egeriae encompassed its host plant’s optimal temperature range of 10 to 35 °C, with lower and upper critical temperatures of 2.6 to 47.0 °C, lower and upper lethal temperatures of − 5.6 and 40.6 °C for adults, and − 6.3 to 41.3 °C for larvae. Results from development time experiments and degree-day accumulation showed that the agent is capable of establishing at all E. densa sites in South Africa, with between 6.9 and 8.3 generations per year. However, cold temperatures (14 °C) prolonged the agent’s development time to three months, allowing it to only develop through one generation in winter. Predictions obtained from laboratory thermal physiology experiments corroborates field data, where the agent has established at all the sites it was released.
- Full Text:
- Date Issued: 2022
- Authors: Smith, Rosali , Coetzee, Julie A , Hill, Martin P
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/417913 , vital:71494 , xlink:href="https://doi.org/10.1007/s10526-022-10142-w"
- Description: The submerged aquatic weed, Egeria densa Planch. (Hydrocharitaceae) or Brazilian waterweed, is a secondary invader of eutrophic freshwater systems in South Africa, following the successful management of floating aquatic weeds. In 2018, the leaf and stem-mining fly, Hydrellia egeriae Rodrigues-Júnior, Mathis and Hauser (Diptera: Ephydridae), was released against E. densa, the first agent released against a submerged aquatic weed in South Africa. During its life stages, the biological control agent is exposed to two environments, air and water. The thermal physiology of both life stages was investigated to optimize agent establishment through fine-tuned release strategies. The thermal physiological limits of H. egeriae encompassed its host plant’s optimal temperature range of 10 to 35 °C, with lower and upper critical temperatures of 2.6 to 47.0 °C, lower and upper lethal temperatures of − 5.6 and 40.6 °C for adults, and − 6.3 to 41.3 °C for larvae. Results from development time experiments and degree-day accumulation showed that the agent is capable of establishing at all E. densa sites in South Africa, with between 6.9 and 8.3 generations per year. However, cold temperatures (14 °C) prolonged the agent’s development time to three months, allowing it to only develop through one generation in winter. Predictions obtained from laboratory thermal physiology experiments corroborates field data, where the agent has established at all the sites it was released.
- Full Text:
- Date Issued: 2022
Big African clay pot, rust color with silver alloy patterns
- Date: 2022 , 2022-10-10
- Subjects: Bam, Brigalia , Pots
- Language: English
- Type: realia , 2022
- Identifier: http://hdl.handle.net/10948/57015 , vital:57270
- Description: African clay pot, rust color with silver alloy patterns. , Women have acquired amazing skills in making clay pots, mats, baskets, etc., to preserve African Women's Art. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-10-10
- Subjects: Bam, Brigalia , Pots
- Language: English
- Type: realia , 2022
- Identifier: http://hdl.handle.net/10948/57015 , vital:57270
- Description: African clay pot, rust color with silver alloy patterns. , Women have acquired amazing skills in making clay pots, mats, baskets, etc., to preserve African Women's Art. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Black and white Xhosa beaded necklace with a woven insert pattern
- Date: 2022 , 2022-09-22
- Subjects: Bam, Brigalia , Beadwork, Xhosa
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56515 , vital:56827
- Description: Black and white Xhosa beaded necklace with a woven insert pattern. This was a gift to Dr. Brigalia Bam from Switzerland. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-22
- Subjects: Bam, Brigalia , Beadwork, Xhosa
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56515 , vital:56827
- Description: Black and white Xhosa beaded necklace with a woven insert pattern. This was a gift to Dr. Brigalia Bam from Switzerland. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Black, pink and blue beaded necklace
- Date: 2022 , 2022-09-22
- Subjects: Bam, Brigalia , Necklaces
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56520 , vital:56832
- Description: Black, pink and blue beaded necklace. This was a gift to Dr. Brigalia Bam from Switzerland. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-22
- Subjects: Bam, Brigalia , Necklaces
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56520 , vital:56832
- Description: Black, pink and blue beaded necklace. This was a gift to Dr. Brigalia Bam from Switzerland. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Blue and white beaded necklace
- Date: 2022 , 2022-09-22
- Subjects: Bam, Brigalia , Necklaces
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56505 , vital:56814
- Description: Blue and white beaded necklace. This was a gift to Dr. Brigalia Bam from Switzerland. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-22
- Subjects: Bam, Brigalia , Necklaces
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56505 , vital:56814
- Description: Blue and white beaded necklace. This was a gift to Dr. Brigalia Bam from Switzerland. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Blue and white ceramic plate with Thomas Jefferson emblem
- Date: 2022 , 2022-09-20
- Subjects: Bam, Brigalia , Ceramic tableware
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56460 , vital:56676
- Description: Blue and white ceramic plate, with the Thomas Jefferson emblem in the center, which was gifted to Dr. Brigalia Bam. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-20
- Subjects: Bam, Brigalia , Ceramic tableware
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56460 , vital:56676
- Description: Blue and white ceramic plate, with the Thomas Jefferson emblem in the center, which was gifted to Dr. Brigalia Bam. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Blue and white rope artifact
- Date: 2022 , 2022-10-11
- Subjects: Bam, Brigalia , Realia
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/57134 , vital:57338
- Description: Blue and white rope artifact, in a brown frame with cream moount board. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-10-11
- Subjects: Bam, Brigalia , Realia
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/57134 , vital:57338
- Description: Blue and white rope artifact, in a brown frame with cream moount board. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Brass trophy
- Date: 2022 , 2022-09-20
- Subjects: Bam, Brigalia , Brasswork
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56450 , vital:56670
- Description: Dr. Bam received a golden brass trophy gift from India when she went there to deliver a lecture. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-20
- Subjects: Bam, Brigalia , Brasswork
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56450 , vital:56670
- Description: Dr. Bam received a golden brass trophy gift from India when she went there to deliver a lecture. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Bronze bottle top opener with Transkei emblem and opal inlay
- Date: 2022 , 2022-10-06
- Subjects: Bam, Brigalia , Figural bottle openers
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56904 , vital:57202
- Description: Bronze bottle top opener with Transkei emblem and opal inlay, gifted to Dr. Brigalia Bam. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-10-06
- Subjects: Bam, Brigalia , Figural bottle openers
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56904 , vital:57202
- Description: Bronze bottle top opener with Transkei emblem and opal inlay, gifted to Dr. Brigalia Bam. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Brown wooden carved statue of a women, with earrings, decorative neck and head jewelry
- Date: 2022 , 2022-10-05
- Subjects: Bam, Brigalia
- Language: English
- Type: statue , realia
- Identifier: http://hdl.handle.net/10948/56854 , vital:57195
- Description: Brown wooden carved statue of a women, with earrings, decorative neck and head jewelry. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-10-05
- Subjects: Bam, Brigalia
- Language: English
- Type: statue , realia
- Identifier: http://hdl.handle.net/10948/56854 , vital:57195
- Description: Brown wooden carved statue of a women, with earrings, decorative neck and head jewelry. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Can Local Knowledge of Small-Scale Fishers Be Used to Monitor and Assess Changes in Marine Ecosystems in a European Context?
- Piñeiro-Corbeira, Cristina, Barrientos, Sara, Barreiro, Rodolfo, Aswani, Shankar, Pascual-Fernández, José, De la Cruz-Modino, Raquel
- Authors: Piñeiro-Corbeira, Cristina , Barrientos, Sara , Barreiro, Rodolfo , Aswani, Shankar , Pascual-Fernández, José , De la Cruz-Modino, Raquel
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/391331 , vital:68642 , ISBN 978-3-031-01980-7 , https://doi.org/10.1007/978-3-031-01980-7_24
- Description: Significance Statement In the last decades, many coastal areas have observed dramatic changes in marine ecosystems, due to anthropogenic and environmental alterations. The general absence of long-term data sets in the marine environment and, more specifically, on benthic and demersal communities represents a severe issue for management and conservation. We propose to incorporate the small-scale fishers’ knowledge and science for better policy recommendations, both in terms of fisheries optimization and resource conservation. Based on two different cases of study with diverse ecosystems, we explore the combination of quantitative and qualitative tools, and participative techniques used to incorporate fishers’ local ecological knowledge. The results highlight fishers’ capacity to identify coastal and marine landscapes resources and changes, reinforcing and complementing the scientific assessment.
- Full Text:
- Date Issued: 2022
- Authors: Piñeiro-Corbeira, Cristina , Barrientos, Sara , Barreiro, Rodolfo , Aswani, Shankar , Pascual-Fernández, José , De la Cruz-Modino, Raquel
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/391331 , vital:68642 , ISBN 978-3-031-01980-7 , https://doi.org/10.1007/978-3-031-01980-7_24
- Description: Significance Statement In the last decades, many coastal areas have observed dramatic changes in marine ecosystems, due to anthropogenic and environmental alterations. The general absence of long-term data sets in the marine environment and, more specifically, on benthic and demersal communities represents a severe issue for management and conservation. We propose to incorporate the small-scale fishers’ knowledge and science for better policy recommendations, both in terms of fisheries optimization and resource conservation. Based on two different cases of study with diverse ecosystems, we explore the combination of quantitative and qualitative tools, and participative techniques used to incorporate fishers’ local ecological knowledge. The results highlight fishers’ capacity to identify coastal and marine landscapes resources and changes, reinforcing and complementing the scientific assessment.
- Full Text:
- Date Issued: 2022
Caricature portraits of SABC Board members
- Date: 2022 , 2022-09-23
- Subjects: Bam, Brigalia
- Language: English
- Type: painting , portrait
- Identifier: http://hdl.handle.net/10948/56615 , vital:56870
- Description: Dr. Brigalia Bam served on the First Board of the South African Broadcasting Corporation (SABC) from 1993 to 1996. Golden framed caricature portrait of the SABC Board Members. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-23
- Subjects: Bam, Brigalia
- Language: English
- Type: painting , portrait
- Identifier: http://hdl.handle.net/10948/56615 , vital:56870
- Description: Dr. Brigalia Bam served on the First Board of the South African Broadcasting Corporation (SABC) from 1993 to 1996. Golden framed caricature portrait of the SABC Board Members. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Carved African wooden pot with a lid
- Date: 2022 , 2022-09-23
- Subjects: Bam, Brigalia , Pots
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56605 , vital:56868
- Description: Carved African wooden pot with a lid, medium sized brown. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-23
- Subjects: Bam, Brigalia , Pots
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56605 , vital:56868
- Description: Carved African wooden pot with a lid, medium sized brown. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Carved wood and brass statuette of an African woman
- Date: 2022 , 2022-10-05
- Subjects: Bam, Brigalia , Sculpture
- Language: English
- Type: Sculptures , realia
- Identifier: http://hdl.handle.net/10948/56864 , vital:57196
- Description: Carved wood and brass statuette of an African woman with earrings and decorative neck and head jewelry. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-10-05
- Subjects: Bam, Brigalia , Sculpture
- Language: English
- Type: Sculptures , realia
- Identifier: http://hdl.handle.net/10948/56864 , vital:57196
- Description: Carved wood and brass statuette of an African woman with earrings and decorative neck and head jewelry. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Ceramic Mother Mary and Baby Jesus figurine
- Date: 2022 , 2022-09-20
- Subjects: Bam, Brigalia , Figurines
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56437 , vital:56664
- Description: Ceramic Mother Mary and Baby Jesus figurine. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-20
- Subjects: Bam, Brigalia , Figurines
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56437 , vital:56664
- Description: Ceramic Mother Mary and Baby Jesus figurine. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Characterising the shared genetic influences between schizophrenia and subcortical brain regions
- Wooton, Olivia, Campbell, Megan, Jahanshad, Neda, Thompson, Paul, Stein, Dan J, Dalvie, Shareefa
- Authors: Wooton, Olivia , Campbell, Megan , Jahanshad, Neda , Thompson, Paul , Stein, Dan J , Dalvie, Shareefa
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/302450 , vital:58197 , xlink:href="https://doi.org/10.1016/j.euroneuro.2022.07.533"
- Description: Background: Abnormalities in brain structural volumes are well established in schizophrenia (SZ) and have been proposed as an endophenotype for the disorder. Despite increasing interest in the genetic relationship between brain structural volumes and SZ, our knowledge of the genetic overlap between the phenotypes is limited. This study aims to extend our current understanding of the shared genetic influences between SZ and subcortical brain volumes using data from the latest genome-wide association studies for the respective phenotypes (GWAS) and novel statistical approaches. Additionally, we will explore whether the association between schizophrenia and abnormal regional brain volumes is causal in nature. Methods: Summary statistics were obtained from the largest Psychiatric Genomic Consortium (PGC)-SZ GWAS (Ncase = 69,369, Ncontrol = 236,642) and the CHARGEENIGMA-UKBB GWAS of volumetric measures for eight subcortical brain regions (the nucleus accumbens, amygdala, brainstem, caudate nucleus, hippocampus, globus pallidus, putamen, and thalamus), and total intracranial volume (N = 30,983 - 40,380). Single nucleotide polymorphism (SNP) effect concordance analysis (SECA) was used to assess pleiotropy and concordance. Genetic correlation was assessed using linkage disequilibrium score regression (LDSR) and the pleiotropy informed conditional FDR approach was applied to identify SNPs associated with SZ conditional on their association with subcortical brain volumes. Mendelian randomization (MR) was used to test for causal association between SZ and each brain region. Results: There was evidence of global pleiotropy between SZ, and all examined subcortical brain regions. Inverse concordance between the genetic determinants of SZ and volumes of the nucleus accumbens, amygdala, brainstem, hippocampus, and thalamus was observed. Increased statistical power to detect SZ risk loci was shown when conditioning on subcortical brain volumes. There was no significant evidence for a causal effect of any of the examined brain regions on schizophrenia risk. Discussion: These data confirm the shared genetic basis of SZ and specific intracranial and subcortical brain volumes and provide evidence for negative concordance between SZ and volumes of the nucleus accumbens, amygdala, brainstem, hippocampus, and thalamus. Leveraging the genetic overlap between SZ and subcortical brain volumes has the potential to provide novel insights into the biological basis of the disorder.
- Full Text:
- Date Issued: 2022
- Authors: Wooton, Olivia , Campbell, Megan , Jahanshad, Neda , Thompson, Paul , Stein, Dan J , Dalvie, Shareefa
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/302450 , vital:58197 , xlink:href="https://doi.org/10.1016/j.euroneuro.2022.07.533"
- Description: Background: Abnormalities in brain structural volumes are well established in schizophrenia (SZ) and have been proposed as an endophenotype for the disorder. Despite increasing interest in the genetic relationship between brain structural volumes and SZ, our knowledge of the genetic overlap between the phenotypes is limited. This study aims to extend our current understanding of the shared genetic influences between SZ and subcortical brain volumes using data from the latest genome-wide association studies for the respective phenotypes (GWAS) and novel statistical approaches. Additionally, we will explore whether the association between schizophrenia and abnormal regional brain volumes is causal in nature. Methods: Summary statistics were obtained from the largest Psychiatric Genomic Consortium (PGC)-SZ GWAS (Ncase = 69,369, Ncontrol = 236,642) and the CHARGEENIGMA-UKBB GWAS of volumetric measures for eight subcortical brain regions (the nucleus accumbens, amygdala, brainstem, caudate nucleus, hippocampus, globus pallidus, putamen, and thalamus), and total intracranial volume (N = 30,983 - 40,380). Single nucleotide polymorphism (SNP) effect concordance analysis (SECA) was used to assess pleiotropy and concordance. Genetic correlation was assessed using linkage disequilibrium score regression (LDSR) and the pleiotropy informed conditional FDR approach was applied to identify SNPs associated with SZ conditional on their association with subcortical brain volumes. Mendelian randomization (MR) was used to test for causal association between SZ and each brain region. Results: There was evidence of global pleiotropy between SZ, and all examined subcortical brain regions. Inverse concordance between the genetic determinants of SZ and volumes of the nucleus accumbens, amygdala, brainstem, hippocampus, and thalamus was observed. Increased statistical power to detect SZ risk loci was shown when conditioning on subcortical brain volumes. There was no significant evidence for a causal effect of any of the examined brain regions on schizophrenia risk. Discussion: These data confirm the shared genetic basis of SZ and specific intracranial and subcortical brain volumes and provide evidence for negative concordance between SZ and volumes of the nucleus accumbens, amygdala, brainstem, hippocampus, and thalamus. Leveraging the genetic overlap between SZ and subcortical brain volumes has the potential to provide novel insights into the biological basis of the disorder.
- Full Text:
- Date Issued: 2022
Circular handmade thatch basket
- Date: 2022 , 2022-09-22
- Subjects: Bam, Brigalia , Basketwork -- Mozambique
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56555 , vital:56855
- Description: Circular handmade thatch basket that was specially made for Dr. Brigalia Bam in Mozambique. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
- Date: 2022 , 2022-09-22
- Subjects: Bam, Brigalia , Basketwork -- Mozambique
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/56555 , vital:56855
- Description: Circular handmade thatch basket that was specially made for Dr. Brigalia Bam in Mozambique. , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 2022
Climatic suitability and compatibility of the invasive Iris pseudacorus L.(Iridaceae) in the Southern Hemisphere: Considerations for biocontrol
- Minuti, Gianmarco, Stiers, Iris, Coetzee, Julie A
- Authors: Minuti, Gianmarco , Stiers, Iris , Coetzee, Julie A
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/423293 , vital:72045 , xlink:href="https://doi.org/10.1016/j.biocontrol.2022.104886"
- Description: Iris pseudacorus L. (Iridaceae) is an emergent macrophyte native to Europe, North Africa and western Asia. Considered invasive in wetland habitats around the world, this species is now the target of a biocontrol programme in the Southern Hemisphere. Native range surveys of the weed led to the selection of the flea beetle, Aphthona nonstriata Goeze (Coleoptera: Chrysomelidae), as a candidate biocontrol agent. An important aspect to consider in weed biocontrol is the ability of an agent to establish and thrive in the environment where it is released. Climatic incompatibility between source and intended release sites can in fact limit the success of a biocontrol programme. In the current study, the potential climatic niche of I. pseudacorus and A. nonstriata in the Southern Hemisphere was analysed. The ecological niche modelling software MaxEnt was used to map the climatic suitability of both organisms across invaded regions in South America, southern Africa and Australasia. Furthermore, occurrence records from each invaded range were used independently to model the climatic compatibility of I. pseudacorus in Europe, in order to prioritize areas of the native range to explore during future surveys for potential biocontrol agents. The models identified areas at high risk of invasion by I. pseudacorus in northern Argentina, Uruguay, southern Brazil and central Chile, as well as numerous provinces of eastern South Africa, Lesotho, southern Australia and New Zealand. Accordingly, the highest climatic suitability for A. nonstriata was predicted across the humid temperate climates of north-east Argentina, Uruguay, southern Brazil, southern South Africa, south-east Australia and New Zealand. These results can eventually be used in future release plans to prioritize areas where establishment and survival of the agent is expected to be highest. At the same time, it may be useful to search the native range of the weed for biological control agents showing high climatic adaptation towards the intended release sites of each invaded range. In this regards, our climatic compatibility models identified high-priority areas across the Mediterranean regions of Italy and southern France, as well as the temperate regions of central and western Europe. Altogether, the current study provides useful new information to tackle the invasion and advance the biocontrol programme of I. pseudacorus in the Southern Hemisphere.
- Full Text:
- Date Issued: 2022
- Authors: Minuti, Gianmarco , Stiers, Iris , Coetzee, Julie A
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/423293 , vital:72045 , xlink:href="https://doi.org/10.1016/j.biocontrol.2022.104886"
- Description: Iris pseudacorus L. (Iridaceae) is an emergent macrophyte native to Europe, North Africa and western Asia. Considered invasive in wetland habitats around the world, this species is now the target of a biocontrol programme in the Southern Hemisphere. Native range surveys of the weed led to the selection of the flea beetle, Aphthona nonstriata Goeze (Coleoptera: Chrysomelidae), as a candidate biocontrol agent. An important aspect to consider in weed biocontrol is the ability of an agent to establish and thrive in the environment where it is released. Climatic incompatibility between source and intended release sites can in fact limit the success of a biocontrol programme. In the current study, the potential climatic niche of I. pseudacorus and A. nonstriata in the Southern Hemisphere was analysed. The ecological niche modelling software MaxEnt was used to map the climatic suitability of both organisms across invaded regions in South America, southern Africa and Australasia. Furthermore, occurrence records from each invaded range were used independently to model the climatic compatibility of I. pseudacorus in Europe, in order to prioritize areas of the native range to explore during future surveys for potential biocontrol agents. The models identified areas at high risk of invasion by I. pseudacorus in northern Argentina, Uruguay, southern Brazil and central Chile, as well as numerous provinces of eastern South Africa, Lesotho, southern Australia and New Zealand. Accordingly, the highest climatic suitability for A. nonstriata was predicted across the humid temperate climates of north-east Argentina, Uruguay, southern Brazil, southern South Africa, south-east Australia and New Zealand. These results can eventually be used in future release plans to prioritize areas where establishment and survival of the agent is expected to be highest. At the same time, it may be useful to search the native range of the weed for biological control agents showing high climatic adaptation towards the intended release sites of each invaded range. In this regards, our climatic compatibility models identified high-priority areas across the Mediterranean regions of Italy and southern France, as well as the temperate regions of central and western Europe. Altogether, the current study provides useful new information to tackle the invasion and advance the biocontrol programme of I. pseudacorus in the Southern Hemisphere.
- Full Text:
- Date Issued: 2022