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AC3P: an architecture using cloud computing for the provision of mathematical powerpoint content to feature phones

- Joubert, Jean-Pierre

Authors: Joubert, Jean-Pierre
Date: 2012
Subjects: Cloud computing , Mobile computing , Mathematics -- Study and teaching.
Language: English
Type: Thesis , Masters , MSc
Identifier: vital:10474 , http://hdl.handle.net/10948/d1011088 , Cloud computing , Mobile computing , Mathematics -- Study and teaching.
Description: The Govan Mbeki Mathematics Development Unit (GMMDU) provides additional mathematics content to learners via mathematics workshops and DVDs. Mathematics is presented in PPT format. The prominence of feature phone usage has been confirmed amongst learners in socio-economic disadvantaged schools, specifically those learners participating in the GMMDU mathematics workshops. Feature phones typically contain limited device resources such as memory, battery power, and network resources. Distributed computing provides the potential to facilitate a new class of mobile applications with the provision of off-device resources. The objective of this research was the design of an architecture using Cloud Computing for the provision of mathematics in the form of PPT slides to feature phones. The capabilities of typical feature phones were reviewed as well as various distributed computing architectures that demonstrate potential benefit to the mobile environment. An Architecture using Cloud Computing for Content Provision (AC3P) was subsequently designed and applied as a proof of concept to facilitate the provision of mathematics in the form of PPT slides to feature phones. The application of AC3P was evaluated for efficiency and effectiveness. It was demonstrated that the application of AC3P provided efficient and effective provision of PPT to feature phones. The successful application of AC3P provided evidence that Cloud Computing may be used to facilitate the provision of mathematics content to feature phones. It is evident that AC3P may be applied in domains other than the provision of mathematics.
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Date Issued: 2012

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Path-dependence and economic geography: a regional economic evolutionary study towards effective LED in marginalised towns

- Phillips, Burton Richard

Authors: Phillips, Burton Richard
Date: 2019
Subjects: Economic geography -- South Africa -- Eastern Cape , Space in economics Regional economics Economic development -- South Africa -- Eastern Cape
Language: English
Type: Thesis , Masters , MBA
Identifier: http://hdl.handle.net/10948/43171 , vital:36754
Description: Small Karoo towns in South Africa, in particular the Easter Cape province has endured marginalised recognition in the development of their local economy and its ability to adapt to social change. The latter has been intensified by shifts in agricultural production, land use, and changing state policy. These aspects are of particular interest to a semi-arid landscape. Agriculture, being the predominant trade, has been subject to various commodity market changes and the diminutive state of farms due to climate changes affecting agricultural estate for feeding and other basic purposes has increased. Parallel to the regressive reasons given, small-towns have been subject to a peculiar rise in population which exacted an increase in dependency on the region’s limited administrative capacity. Local economic development (LED) projects are, more often than not, transitory and contribute very little to the town’s sustainability. Underpinning poor development are challenges such as an inability to acquire necessary human capital as well as good public administration and a supporting private business stakeholder relationship. Literature on strategies for small-town development seldom addresses the unique circumstances interweaved with their own casual complexities. Thus, an evolutionary geography approach was proposed which considers the economy of an area as an evolutionary process that unfolds in space and time. It entails a comparative analysis of an economy’s past decisions (history) and geographical changes (spatial). Moreover, adding a significant contribution to the rationale of this study is the opportunity to explore the concept and reality of marginalisation in the former Baviaanskloof Local Municipality (BLM). The aim thereof, to ascertain whether geography (i.e., natural advantages) or histories (i.e., man-made advantages) are the main determinants for the spatial distribution of economic activity, and what place-dependent strategies are most suitable to deliver effective LED.
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Date Issued: 2019

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Assessment of drug resistant Tuberculosis and Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome: knowledge levels among community members in Nelson Mandela Metropolitan Municipality

- Fana, Thanduxolo

Authors: Fana, Thanduxolo
Date: 2013
Subjects: Multidrug-resistant tuberculosis -- South Africa -- Port Elizabeth , Tuberculosis -- South Africa -- Port Elizabeth -- Prevention
Language: English
Type: Thesis , Masters , MPA
Identifier: vital:8276 , http://hdl.handle.net/10948/d1016076
Description: The aim of this study was to assess community members’ knowledge levels regarding Drug Resistant TB and HIV and AIDS. The study was conducted at ward 40 in Green bushes area in Nelson Mandela Metropolitan Municipality (NMMM). A quantitative research method was used in this study. Random sampling is the type of probability sampling method that was used in this study. The sample consisted of 100 respondents above 18 years who were randomly selected from the beneficiary list of for the RDP houses in Green bushes area in the Nelson Mandela Metropolitan Municipality. Data for this study were collected using close ended questions which were administered by the researcher to the selected participants. Data was analysed using bivariate and descriptive statistics according to the identified themes. The study revealed that community members had high knowledge levels regarding Drug Resistant TB and HIV and AIDS prevention, transmission modes and diagnosis and treatment methods. The findings revealed that community members were highly knowledgeable and aware of the fact that abstaining and practising safe sex were means of preventing the spread of HIV and AIDS as it was spread through unprotected sex, while opening of windows and minimisation of close contact with HIV positive people and children with people infected with Drug Resistant TB are infection control measures or methods of preventing the spread of the disease. Additionally, the study indicated that female respondents were more aware and knowledgeable about prevention, transmission modes and diagnosis and treatment of Drug Resistant TB and HIV and AIDS than male respondents. Furthermore, the findings revealed that the respondents were highly knowledgeable and aware about transmission of Drug Resistant TB and HIV and AIDS; knowledgeable about prevention and less knowledgeable about diagnosis and treatment. A high percentage of female respondents knew that there was no vaccine to neither prevent nor cure HIV and AIDS and that antiretroviral drug were used to manage it. The study also showed that female respondents knew that all people irrespective of race and economic class can be infected with Drug Resistant TB and HIV and AIDS. It is important to note that the respondents between 41-60 years possessed more knowledge regarding Drug Resistant TB and HIV and AIDS than the respondents who were between 18-40 years. Lastly, the study showed that there were significant differences in gender and knowledge and no significant differences in age and knowledge of the respondents regarding Drug Resistant TB and HIV and AIDS. It is recommended that in future, research regarding knowledge levels about Drug Resistant TB and HIV and AIDS be extended to other wards in the Nelson Mandela Metropolitan Municipality (NMMM). Accurate knowledge should be provided by ensuring that educational materials that are developed, are appropriate for the various levels of literacy, and that more appropriate and relevant information regarding these diseases is made more accessible to community members in their home languages. The researcher further recommends that during training interventions and educational campaigns more emphasis should be put on prevention, diagnosis and treatment of Drug Resistant TB and HIV and AIDS.
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Date Issued: 2013

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Development and in vitro evaluation of a clobetasol 17-propionate topical cream formulation

- Wa Kasongo, Kasongo

Authors: Wa Kasongo, Kasongo
Date: 2007
Subjects: Adrenocortical hormones , Adrenocortical hormones -- Physiological effect , Drugs -- Testing , Drug development , Dermatopharmacology
Language: English
Type: Thesis , Masters , MPharm
Identifier: vital:3799 , http://hdl.handle.net/10962/d1003277 , Adrenocortical hormones , Adrenocortical hormones -- Physiological effect , Drugs -- Testing , Drug development , Dermatopharmacology
Description: One of the primary contributing factors to the escalating costs of health care is the high cost of innovator pharmaceutical products. As a consequence, health authorities in various countries and in particular in the developing world have identified generic prescribing and generic substitution as possible strategies to contain the escalating costs of health care provision. There is therefore a need for formulation scientists in developing countries to invest more time in the research and development of generic formulations. Clobetasol 17-propionate (CP) generic cream formulations containing 0.05% w/w of the drug were manufactured and characterized using in vitro testing. Formulation development studies were preceded by the development and validation of an RP-HPLC with UV detection for the quantitation and characterization of CP in innovator and generic cream formulations during formulation development and assessment studies. Furthermore the in vitro release ates of CP release from innovator and generic cream formulations were monitored using a validated in vitro release test method developed in these studies. The formulation of CP cream products was accomplished using a variety of commercially available mixed primary emulsifiers, such as Estol® 1474, Ritapro® 200, Emulcire® 61 WL and Gelot® 64. Successful formulations were selected based on their ability to remain physically stable immediately after manufacture and for 24 hours after storage at room temperature (22°C). Estol® 1474 was found to produce an unstable cream and was therefore not investigated further. The other three emulgents produced stable creams, but only the in vitro release profile of CP from a cream manufactured to contain Gelot® 64 was found to be statistically similar to that of the innovator formulation. Therefore the cream containing Gelot® 64 was selected as the most appropriate prototype generic cream formulation and was characterized in vitro in terms of CP content, viscosity, pH and in vitro release rate. Data generated from these studies were compared to those of the innovator product, Dermovate® cream, using statistical methods. The CP content, pH and in vitro release rate data of the CP formulation were similar to those of the innovator product, however the intrinsic viscosity of Dermovate® cream was almost three (3) times greater than the intrinsic viscosity of the test formulation developed using Gelot® 64. The CP cream formulation developed in these studies was stored for 4 weeks at 40 ± 2°C and 25 ± 5% RH in an incubator and the formulation was found to be stable. A formulation has been developed and assessed and found to be suitable for use as a topical semi-solid dosage form for CP.
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Date Issued: 2007

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Improving the effectiveness of training in Sanlam sky

- Gonya, Odwa Otto

Authors: Gonya, Odwa Otto
Date: 2017
Subjects: Employees -- Training of -- Evaluation Occupational training
Language: English
Type: Thesis , Masters , MBA
Identifier: http://hdl.handle.net/10948/15116 , vital:28140
Description: Sanlam Sky is a division of the Sanlam Group focusing on the developing markets. The division plays an important role in employing previously disadvantaged people with little or no prior training and experience. Training is the methodical development of Knowledge, Skills and Attitude that is required by the employee to perform a given task on the job satisfactorily. The training department therefore has a key responsibility of providing effective training to the newly appointed and existing employees and can be viewed as an essential vehicle for company success. The study identified that investment is allocated for the training and development of employees over the past years at Sanlam Sky and the organisation has not measured the effectiveness of training prior to this study. The main purpose of this study was to determine if the training initiatives at Sanlam Sky are effective or not and then identify factors to improve effectiveness of training at Sanlam Sky. The study also addresses the question of “what are the assessment methods for measuring T&D effectiveness that exist in the literature?” The empirical study included the distribution of a self-administered questionnaire amongst operations and distribution staff. Data was collected from multiple sources including 88 respondents and triangulated with unstructured interview data sourced from the learning managers; this data was used to assess the effectiveness of training and develop strategies for improvement. The findings indicate that the training provided at Sanlam Sky is effective, however there are no clear guidelines on identifying training needs in the organisation. The study identified that there is no evaluation framework that is used at Sanlam Sky. The trainees are not given an opportunity to choose how they want their training to be facilitated. Hypothesis of the study was tested and finally the study offers recommendations to be implemented in improving the effectiveness of training.
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Date Issued: 2017

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A comparison of the aquaculture potential of Clarias gariepinus (Burchell, 1822) and its hybrid with Heterobranchus longifilis valenciennes, 1840 in Southern Africa

- Oellermann, Lawrence Keith

Authors: Oellermann, Lawrence Keith
Date: 1996
Subjects: Aquaculture -- South Africa Clarias Clariidae Catfishes -- South Africa
Language: English
Type: Thesis , Doctoral , PhD
Identifier: vital:5246 , http://hdl.handle.net/10962/d1005089
Description: The aim of this study was to evaluate the aquaculture potential of a hybrid between the two largest African silurid catfish, Heterobranchus longifilis (HL) and Clarias gariepinus (CG) . A morphometric, meristic and karyological study showed that the hybrid shared some of the physical characteristics of both C. gariepinus and H. longifilis, while its chromosome complement and fundamental number (2N = 54, FN = 95), was intermediate between that of H. longifilis (2N = 52, FN = 92) and C. gariepinus (2N = 56, FN = 97). The HLxCG cross could therefore be regarded as a true hybrid. For the characters tested, no morphological or karyological differences were apparent between the HLxCG hybrids produced in West Africa and those produced in southern Africa. In southern Africa, the HL♂xCG♀ cross had higher fertilization and hatching rates than pure strain H. longifilis, C. gariepinus or the reverse cross. There was no difference in the survival of the HL♂xCG♀ hybrid larvae and C. gariepinus larvae up to the onset of exogenous feeding. Pure strain H. longifilis juveniles had a faster growth rate than the H. longifilis ♂ x C. gariepinus ♀ juveniles, but the hybrid always grew at a faster rate than C. gariepinus or the reverse cross. The HL♂xCG♀ cross was consequently chosen as the hybrid with the greatest potential for siluroid aquaculture in southern Africa. The HL♂xCG♀ hybrid showed evidence of partial gonadic, gametic and post-zygotic sterility in both sexes. The hybrid was not completely sterile, as it was artificially induced to spawn, and a small number of viable F₂ hybrid and F₁ hybrid x C. gariepinus larvae were produced. However, in the light of its probable reproductive strategy, it is highly unlikely that the hybrid would pose an ecological risk to the southern African region. The H. longifilis ♂ x C. gariepinus ♀ hybrid was compared to C. gariepinus for selected water quality preferences and tolerances. The hybrid had a wider temperature preference (28 °C to 34 °C) than C. gariepinus (28 °C to 30 °C), but appeared to be more dependent on aerial respiration than C. gariepinus. The air-breathing frequency of hybrid fish began to increase at dissolved oxygen concentrations below 3 .8 mg.ℓ⁻¹, while C. gariepinus only showed an increase in air-breathing frequency at concentrations below 3.0 mg.ℓ¹. The hybrid was more tolerant of un-ionised ammonia (96-hour LC₅₀ = 9.1 mg.ℓ⁻¹) than C. gariepinus (96-hour LC₅₀ = 6.5 mg.ℓ⁻¹), but their 96-hour LC₅₀ salinity tolerances were similar (10.8-11.0 g.ℓ⁻¹). The H. longifilis ♂ x C. gariepinus ♀ hybrid had a higher fillet yield (43.9 %) than C. gariepinus (38.9 %), but the crude protein content and amino acid profile of the two groups were similar. Catfish are traditionally grown in earthen ponds under semi-intensive conditions in southern Africa, at around 4 kg of fish per cubic meter of water (kg.m⁻³). However, the hybrid could tolerate densities of up to 415 kg of fish per cubic metre of water, if the water was exchanged hourly (kg.m⁻³.hr⁻¹), and the density at which yield was optimised was rounded off to 400 kg.m³.hr⁻¹. The high threshold density and water quality tolerances of the H. longifilis ♂ x C. gariepinus ♀ hybrid indicates that it is ideally suited for highly intensive aquaculture. It was concluded that it would be more productive to farm the HL♂xCG♀ hybrid on an intensive basis in southern Africa, than it would be to farm C. gariepinus in the traditional manner.
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Date Issued: 1996

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The nature of the barriers separating the Lake Malawi and Zambezi fish faunas

- Tweddle, D S C, Lewis, Digby S C, Willoughby, N G

Authors: Tweddle, D S C , Lewis, Digby S C , Willoughby, N G
Date: 1979
Language: English
Type: Text
Identifier: vital:15018 , http://hdl.handle.net/10962/d1019797 , ISBN 086810003X , Ichthyological Bulletin of the J.L.B. Smith Institute of Ichthyology; No. 39
Description: Part 1: The nature of the barriers separating the Lake Malawi and Zambezi fish faunas: The nature of the barrier separating the ‘Lake Malawi’ from the ‘Lower Zambezi’ fish faunas was investigated by electrofishing the 145 km stretch of the Shire River surrounding the Murchison cataracts. The study shows that the lowermost element of the cataracts, the Kapachira Falls, is an absolute physical barrier to upstream movement of ‘Lower Zambezi’ species. The barrier to downstream movement by ‘Lake Malawi’ species is largely ecological and has two components, the fluviatile nature of the Upper and Middle Shire and especially the torrential nature of the cataracts, which are unsuitable for lacustrine species, and competition with the ‘Lower Zambezi’ fauna of the Lower Shire by the few species which succeed in negotiating the cataracts. , Part 2: An annotated checklist of the fish fauna of the River Shire south of Kapachira Falls, Malawi: The Shire River drains Lake Malawi and is a major tributary of the Lower Zambezi River. Sixty-one species of fish have been recorded in the lower reaches which are separated from the lower Shire basin by the Kapachira Falls and from the ‘East Coast River’ fauna present in the Upper Ruo River by the Zoa Falls. The fauna is essentially similar to that of the Lower Zambezi, although some Lake Malawi endemics occur sporadically in the upper part of the flood plain. , Rhodes University Libraries (Digitisation)
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Date Issued: 1979

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Photophysical and photochemical behaviour of metallophthalocyanines effect of nanoparticles and molecules of biological importance

- Idowu, Mopelola Abidemi

Authors: Idowu, Mopelola Abidemi
Date: 2009
Subjects: Electrochemistry Phthalocyanines Nanoparticles
Language: English
Type: Thesis , Doctoral , PhD
Identifier: vital:4329 , http://hdl.handle.net/10962/d1004990
Description: Syntheses, spectral, photophysical and photochemical studies of some neutral, anionic and cationic metallophthalocyanine derivatives are presented. The effects of central metal ions, solvents, aggregation, surfactant, nanoparticles and bovine serum albumin on the photophysical and photochemical behaviour are investigated. Mercaptocarboxylic acid stabilized CdTe quantum dots (QDs) were used as energy donors to anionic water-soluble MPcs through Förster resonance energy transfer (FRET). Energy transfer (ET) from the QDs to the MPcs occurred upon photoexcitation of the QDs. An enhancement in efficiency of ET with the nature of the cappings on the QDs was observed with few occurrences of a non-Förster type ET. QDs were found to improve the photophysicochemical behaviour of the MPcs, with the possibility of indirect production of singlet oxygen (Φ[subscript Δ]) via FRET mechanism. Interaction of the QDs with cationic water-souble MPcs produced ion-pair complexes resulting in aggregates due to strong electronic coupling. The stoichiometry of the reaction and association constants are evaluated by the continuous variation method. Improved photophysicochemical behaviour with no spectral alterations was observed in MPcs in the presence of magnetic fluid. Complexes showed high triplet quantum yields with corresponding long lifetimes and high photostability. Elucidation of the results of the interaction of bovine serum albumin (BSA) with MPcs or QDs is presented. Increased efficiency of Φ[subscript Δ] generation of MPcs in the presence of BSA coupled with large binding constants, suggesting strong interaction of the MPcs with BSA was observed. Enhanced emission intensity of QDs when linked to or in a mixture with BSA due to radiationless recombination at the surface vacancies was also observed. The study revealed positive deviation from Stern-Volmer relationship suggesting the occurrence of static and dynamic mechanisms of quenching together. Fluorescence quenching of the MPcs by benzoquinone, analysed by Stern-Volmer relationship is also presented; the results were employed in determining fluorescence lifetimes of the complexes. Photoelectrochemical characteristics of MPc-sensitized electrodeposited ZnO thin films were studied; ZnOCPc / ZnO films have been improved to an incident photon-to-currentconversion (IPCE) value of 31.1 % with an absorbed photon-to-current conversion (APCE) of 59.6 %. The best obtained so far with phthalocyanine-type sensitizers on nanocrystalline ZnO films. Fluorescent-magnetic nanocomposite with excellent photophysical properties which can be exploited for combined photodynamic and hyperthermia therapies is also presented.
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Date Issued: 2009

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The new townsmen: the legal position of the African in the white areas today

- Wollheim, O D

Authors: Wollheim, O D
Date: 1964
Subjects: South Africa. Bantu Labour Act, No. 67 of 1964 , Segregation -- Law and legislation -- South Africa , Civil rights -- South Africa , Apartheid -- South Africa , South Africa -- Race relations -- 20th century , South Africa -- Social conditions -- 1961-1994 , Human rights -- South Africa -- History -- 20th century
Type: Text
Identifier: http://hdl.handle.net/10962/61241 , vital:27996 , Pamhlet Box 267 , This manuscript is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017.
Description: This study of urban African legislation is prompted by the widespread public interest in the controversial Bantu Laws Amendment Acts — now in force as the Bantu Labour Act, No. 67 of 1964. It will seek to give a picture of the purpose and effect of this legislation.
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Date Issued: 1964

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Book Review:‘These Traits Portend’: review of Thabo Mbeki and the Struggle for the Soul of the ANC by William Mervyn Gumede

- Wright, Laurence

Authors: Wright, Laurence
Date: 2005
Language: English
Type: text , article
Identifier: vital:7049 , http://hdl.handle.net/10962/d1007391 , https://www.researchgate.net/publication/29807204_Book_Review_'These_Traits_Portend'_Review_of_Thabo_Mbeki_and_the_Struggle_for_the_Soul_of_the_ANC_by_William_Mervyn_Gumede_Cape_Town_Zebra_Press_2005
Description: preprint , “The identity of the old ANC is changing fast and its soul is becoming harder to locate” – so writes William Gumede in his best-selling account of the Mbeki presidency. This is a thoroughly admirable book, critical, informed and deeply concerned with the welfare of the people of South Africa, especially the poor – with no taint of political hagiography. The central plank of the critique concerns the ANC’s management of the economy. Gumede’s account of the genesis of GEAR and the devious way it was sprung on the tri-partite alliance is illuminating. It was done under the rubric of necessary modernization, according to Gumede, and allegiance to the Blair/Schroeder Third Way. But there were huge ancillary consequences: the loss of influence by the ordinary ANC membership, neglect of branch activity, sidelining of the parliamentary caucus, centralization of policy development in the office of the president, increasing reliance on consultants and relentless cosying up to big business.
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Date Issued: 2005

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Photochemical studies of tetra-2, 3-pyridinoporphyrazines

- Seotsanyana-Mokhosi, Itumeleng, Kuznetsova, Nina, Nyokong, Tebello

Authors: Seotsanyana-Mokhosi, Itumeleng , Kuznetsova, Nina , Nyokong, Tebello
Date: 2001
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/291580 , vital:56889 , xlink:href="https://doi.org/10.1016/S1010-6030(01)00427-0"
Description: Tetra-2,3-pyridinoporphyrazines and the corresponding water-soluble N,N′,N′′,N′′′-tetramethyl-tetra-2,3-pyridinoporphyrazine complexes, containing central metal atoms; M=Ge, Sn, Si and Zn, were synthesized and their photochemical properties were investigated. The reductive quenching of pyridinoporphyrazines excited states, enhanced relative to phthalocyanines, was considered as the first photochemical step of dyes phototransformation in dimethylformamide (DMF) and dimethylsulfoxide (DMSO) solutions under irradiation with visible light. Efficiency of singlet oxygen photosensitization decreases significantly in the row phthalocyanines, unquaternized, quaternized tetra-2,3-pyridinoporphyrazine metallocomplexes.
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Date Issued: 2001

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Cordidepsine is A Potential New Anti-HIV Depsidone from Cordia millenii

- Zeukang, Rostanie D, Siwe-Noundou, Xavier, Fotsing, Maurice T, Mbafor, Joseph T, Krause, Rui W M, Choudhary, Muhammad I, Atchade, Alex de Theodore

Authors: Zeukang, Rostanie D , Siwe-Noundou, Xavier , Fotsing, Maurice T , Mbafor, Joseph T , Krause, Rui W M , Choudhary, Muhammad I , Atchade, Alex de Theodore
Date: 2019
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/193988 , vital:45413 , xlink:href="https://doi.org/10.3390/molecules24173202"
Description: Chemical investigation of Cordia millenii, Baker resulted in the isolation of a new depsidone, cordidepsine (1), along with twelve known compounds including cyclooctasulfur (2), lup-20(29)-en-3-triacontanoate (3), 1-(26-hydroxyhexacosanoyl)glycerol (4), glyceryl-1-hexacosanoate (5) betulinic acid (6), lupenone (7), β-amyrone (8), lupeol (9), β-amyrin (10), allantoin (11), 2′-(4-hydroxyphenyl)ethylpropanoate (12) and stigmasterol glycoside (13). Hemi-synthetic reactions were carried out on two isolated compounds (5 and 6) to afford two new derivatives, that is, cordicerol A (14) and cordicerol B (15), respectively. The chemical structures of all the compounds were established based on analysis and interpretation of spectroscopic data such as electron ionization mass spectrometry (EI–MS), high resolution electrospray ionization mass spectrometry (HR-ESI–MS), fast atom bombardment mass spectrometry (FAB–MS), one dimension and two dimension nuclear magnetic resonance (1D and 2D-NMR) spectral data as well as X-ray crystallography (XRC). Lupeol ester derivatives [Lup-20(29)-en-3-triacontanoate (3)], monoglycerol derivatives [1-(26-hydroxyhexacosanoyl)glycerol (4) and glyceryl-1 hexacosanoate (5)] were isolated for the first time from Cordia genus while sulfur allotrope [cyclooctasulfur (2)] was isolated for the first time from plant origin. Biological assays cordidepsine (1) exhibited significant anti-HIV integrase activity with IC50 = 4.65 μM; EtOAc extract of stem barks, EtOAc fraction of roots and leaves were not toxic against 3T3 cells.
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Date Issued: 2019

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Hepatitis C and HIV Coinfection in Developing Countries:

- Tastan Bishop, Özlem

Authors: Tastan Bishop, Özlem
Date: 2018
Language: English
Type: text , book
Identifier: http://hdl.handle.net/10962/148228 , vital:38721 , ISBN 9780128032343 , https://books.google.co.za/books?id=XSmlCgAAQBAJanddq=hepatitis+c+in+developing+countriesandsource=gbs_navlinks_s
Description: Because of the common routes of transmission, hepatitis C virus (HCV) coinfection with HIV is frequent. Of the 36.6 million HIV-infected individuals worldwide, about 25% are also coinfected with HCV. Developing countries face the greatest burden of coinfection. HIV infection has been shown to have a significant impact on the progression of chronic HCV, with a higher risk of cirrhosis and hepatocellular carcinoma (HCC). Because of the improvements in the management and treatment of HIV/AIDS in resource-limited countries, HCV/HIV coinfection is becoming a significant clinical problem and a major cause of morbidity and mortality. HCV/HIV coinfection is characterized by aggressive hepatic fibrogenesis, incidence of cirrhosis, and HCC. HCC is currently a major cause for liver-related deaths in HIV patients. Viral eradication has been difficult to attain with interferon and ribavirin therapies. Novel therapies with direct-acting antiviral agents have been promising for this population. However, access to such expensive regimen is far beyond the capabilities of most resource-limited countries. Yet, studies lag behind those for HCV monoinfection.
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Date Issued: 2018

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Community leadership in Grahamstown

- Van der Merwe, Hendrik W

Authors: Van der Merwe, Hendrik W
Date: 1967
Subjects: Sociology, Urban -- South Africa -- Grahamstown , Community leadership -- South Africa -- Grahamstown , Community development, Urban -- South Africa -- Grahamstown
Language: English
Type: Thesis , Masters , MA
Identifier: vital:3390 , http://hdl.handle.net/10962/d1014564
Description: In this study an analysis was made of the leadership structure of the community of Grahamstown. It was hypothesized that the leadership structure is pluralistic i.e. that leaders are divided along themselves on different issues. An historical and documentary analysis of various aspects of community life revealed that leaders were not united on almost all issues. An analysis of the voluntary associations in which the top leaders took an active part revealed great discrepancy in terms of orientation toward the community, society, and social exclusiveness. A schedule was administered to 90 leaders who were identified by the Cooperating- Informant Technique. Data. were collected about their background characteristics, attitudes toward certain local issues and their general ideological orientations. It was found that stands taken on local issues can best be interpreted in terms of ideological orientation. We conclude that local community leadership is pluralistic. In view of the relationship between local issues and the larger society, several selected problems merit further investigation.
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Date Issued: 1967

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The use of computer-based management information systems as a recruitment tool an assessment of the attitudes of recruitment agents in a selected area of the Western Cape on 10 February 2004

- Victor, Louana

Authors: Victor, Louana
Date: 2004
Subjects: Employment agencies -- South Africa -- Western Cape -- Evaluation , Employee selection -- South Africa -- Western Cape -- Data processing , Management information systems -- South Africa -- Western Cape
Language: English
Type: Thesis , Masters , MA
Identifier: vital:10997 , http://hdl.handle.net/10948/342 , Employment agencies -- South Africa -- Western Cape -- Evaluation , Employee selection -- South Africa -- Western Cape -- Data processing , Management information systems -- South Africa -- Western Cape
Description: Recruitment and selection has become a specialised industry and is competing in a global market. To remain competitive, recruitment agents have to stay ahead of their competitors, by providing an excellent service to customers and applicants, and by keeping up with technological developments in their field. The current investigation focuses on an assessment of the attitudes of recruitment agents in a selected area of the Western Cape Province to the use of computer-based management information systems as a recruitment tool. A questionnaire was distributed amongst recruitment agents in the identified area. It focused on recruiter biographical information, the services they offer, the methods and processes they use in recruitment, the knowledge and skills they need in their field, and their knowledge and attitude towards electronic-recruitment. The literature indicated a move towards using technology in the field of recruitment, and this was consistent with the findings of the study. Although the respondents were familiar with developments in technology used for recruitment, only a small number were familiar with the major business information systems, namely, SAP R/3, Oracle and PeopleSoft. Information specifically related to recruitment agents in South Africa was limited, but the study provided some insight into this field. It was found that recruitment agents disagree on what a good advertisement, as well as a good résumé, should contain, and this is problematic as these are two of the most important things that recruitment agents work with every day. The literature provided no indication of the qualifications needed by a recruitment agent, and resulting from this, a second finding of the study indicated that, according to the respondents, the qualifications needed by a recruitment agent are varied. It was found that qualifications of the sample group varied from only a school-leaving certificate to post-graduate degrees. A significant trend identified that only 24.2 per cent of recruitment agents are involved in research related to recruitment, and write articles related to their field. This contributes to the fact that so little information is available about South African recruitment agents. The study indicated that recruitment agents hold a positive attitude towards computer-based information systems, although they are accepted with caution because of various logistical problems in the South African market. The study also provided useful information to start a process of drawing up a profile of the South African recruitment agency business.
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Date Issued: 2004

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