Interacting motif networks located in hotspots associated with RNA release are conserved in Enterovirus capsids
- Ross, Caroline J, Knox, Caroline M, Tastan Bishop, Özlem
- Authors: Ross, Caroline J , Knox, Caroline M , Tastan Bishop, Özlem
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124855 , vital:35704 , https://doi.10.1002/1873-3468.12663
- Description: Enteroviruses are responsible for a multitude of human diseases. Expansion of the virus capsid is associated with a cascade of conformational changes that allow the subsequent release of RNA. For the first time, this study presents a comprehensive bioinformatic screen for the prediction of interacting motifs within intraprotomer interfaces and across respective interfaces surrounding the fivefold and twofold axes. The results identify a network of conserved motif residues involved in interactions in enteroviruses that may be critical to capsid stabilisation, providing guidelines towards developing antivirals that interfere with viral expansion during RNA release.
- Full Text:
- Date Issued: 2017
- Authors: Ross, Caroline J , Knox, Caroline M , Tastan Bishop, Özlem
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124855 , vital:35704 , https://doi.10.1002/1873-3468.12663
- Description: Enteroviruses are responsible for a multitude of human diseases. Expansion of the virus capsid is associated with a cascade of conformational changes that allow the subsequent release of RNA. For the first time, this study presents a comprehensive bioinformatic screen for the prediction of interacting motifs within intraprotomer interfaces and across respective interfaces surrounding the fivefold and twofold axes. The results identify a network of conserved motif residues involved in interactions in enteroviruses that may be critical to capsid stabilisation, providing guidelines towards developing antivirals that interfere with viral expansion during RNA release.
- Full Text:
- Date Issued: 2017
Interrogating citizen journalism practices: a case study of Rhodes University’s Lindaba Ziyafika Project
- Nyathi, Sihle, Garman, Anthea
- Authors: Nyathi, Sihle , Garman, Anthea
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158915 , vital:40240 , https://doi.org/10.1080/23743670.2016.1259740
- Description: Several scholars have noted that citizen journalism in the West is essentially an online phenomenon, driven by the affordability of Internet technologies. In Africa, projects such as Ushahidi in Kenya have been enabled by platforms such as cell phones and social networks. Voices of Africa, based in southern Africa, publishes on the web only. Publishing on the Internet presumes a citizenry which is relatively well educated; has familiarity with, and access to, new media as a form of social communication; and is confident in their right to participate in newly developed public spheres – particularly those online.
- Full Text:
- Date Issued: 2017
- Authors: Nyathi, Sihle , Garman, Anthea
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158915 , vital:40240 , https://doi.org/10.1080/23743670.2016.1259740
- Description: Several scholars have noted that citizen journalism in the West is essentially an online phenomenon, driven by the affordability of Internet technologies. In Africa, projects such as Ushahidi in Kenya have been enabled by platforms such as cell phones and social networks. Voices of Africa, based in southern Africa, publishes on the web only. Publishing on the Internet presumes a citizenry which is relatively well educated; has familiarity with, and access to, new media as a form of social communication; and is confident in their right to participate in newly developed public spheres – particularly those online.
- Full Text:
- Date Issued: 2017
Is contemporary art postdevelopmental?: a study of ‘art as NGO’
- Authors: Tello, Verónica
- Date: 2019
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/146365 , vital:38519 , ISBN 9780429959981
- Description: Book abstract. Postdevelopment in Practice critically engages with recent trends in postdevelopment and critical development studies that have destabilised the concept of development, challenging its assumptions and exposing areas where it has failed in its objectives, whilst also pushing beyond theory to uncover alternatives in practice.
- Full Text:
- Date Issued: 2019
- Authors: Tello, Verónica
- Date: 2019
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/146365 , vital:38519 , ISBN 9780429959981
- Description: Book abstract. Postdevelopment in Practice critically engages with recent trends in postdevelopment and critical development studies that have destabilised the concept of development, challenging its assumptions and exposing areas where it has failed in its objectives, whilst also pushing beyond theory to uncover alternatives in practice.
- Full Text:
- Date Issued: 2019
Know your rights! A basic guide for domestic workers in South Africa
- Labour Research Service (LRS)
- Authors: Labour Research Service (LRS)
- Date: 2010-06
- Subjects: Household employees -- Legal status, laws, etc. -- South Africa , Household employees -- Employment -- South Africa , Labour contract -- South Africa
- Language: English
- Type: book , text
- Identifier: http://hdl.handle.net/10962/60041 , vital:27725
- Description: The demand for domestic services has increased globally during the last two decades and today domestic workers constitute a large portion of the workforce, especially in developing countries. Yet domestic work is undervalued and poorly regulated, and many domestic workers are underpaid and unprotected. This has been recognised by international organisations, such as the International Labour Organisation (ILO). The struggle of domestic workers has lead to improvements to their rights and conditions in many countries. Yet working conditions and wages remain poor in many countries, including South Africa. This booklet sheds light on this problem. There are 888 000 domestic workers in South Africa, which accounts for 7% of total formal employment (Labour Force Survey, May 2010). The vast majority of these workers do not belong to a trade union and do not partake in collective bargaining or are unaware of their rights to bargain and to join trade unions. The South African Domestic Services and Allied Workers Union (SADSAWU) is a trade union for domestic workers in South Africa and campaigns for the improvement of rights and conditions of domestic workers. It recognises that it is not as powerful as it could be and it would have a bigger influence on the legislating authorities if there were more members which were strongly organised. There are numerous difficulties to organise domestic workers, some are related to the education level of the workers and some lies within the nature of the work (many are live-in workers and therefore have no contact with other domestic workers as a natural part of their work). However, SADSAWU has over many years built up a lot of experience and developed a solid vision to build a strong domestic workers movement, and is therefore well placed to fight these difficulties. This booklet also serves as an organising tool for domestic workers. The aim is to raise awareness of the rights of domestic workers and to encourage workers to organise.
- Full Text:
- Date Issued: 2010-06
- Authors: Labour Research Service (LRS)
- Date: 2010-06
- Subjects: Household employees -- Legal status, laws, etc. -- South Africa , Household employees -- Employment -- South Africa , Labour contract -- South Africa
- Language: English
- Type: book , text
- Identifier: http://hdl.handle.net/10962/60041 , vital:27725
- Description: The demand for domestic services has increased globally during the last two decades and today domestic workers constitute a large portion of the workforce, especially in developing countries. Yet domestic work is undervalued and poorly regulated, and many domestic workers are underpaid and unprotected. This has been recognised by international organisations, such as the International Labour Organisation (ILO). The struggle of domestic workers has lead to improvements to their rights and conditions in many countries. Yet working conditions and wages remain poor in many countries, including South Africa. This booklet sheds light on this problem. There are 888 000 domestic workers in South Africa, which accounts for 7% of total formal employment (Labour Force Survey, May 2010). The vast majority of these workers do not belong to a trade union and do not partake in collective bargaining or are unaware of their rights to bargain and to join trade unions. The South African Domestic Services and Allied Workers Union (SADSAWU) is a trade union for domestic workers in South Africa and campaigns for the improvement of rights and conditions of domestic workers. It recognises that it is not as powerful as it could be and it would have a bigger influence on the legislating authorities if there were more members which were strongly organised. There are numerous difficulties to organise domestic workers, some are related to the education level of the workers and some lies within the nature of the work (many are live-in workers and therefore have no contact with other domestic workers as a natural part of their work). However, SADSAWU has over many years built up a lot of experience and developed a solid vision to build a strong domestic workers movement, and is therefore well placed to fight these difficulties. This booklet also serves as an organising tool for domestic workers. The aim is to raise awareness of the rights of domestic workers and to encourage workers to organise.
- Full Text:
- Date Issued: 2010-06
Labour after globalisation: old and new sources of power
- Authors: Webster, Edward
- Date: 2015
- Subjects: Globalization Labor market Labor and globalization Labor and economy Labor economics Labor supply -- Effect of automation on
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/3093 , vital:20368 , ISBN 9780868104867
- Description: In this paper I focus on building a conceptual framework for an understanding of the changing dynamics of labour and workers’ sources of power. I begin by identifying worker action that draws on traditional sources of structural and associational power. I then show how the emergence of new forms of labour action is drawing on both old and new sources of power. New global forms of worker power are examined, and I conclude by suggesting that the missing dimension in the three sources of power identified – structural, associational and societal – is institutional power. If these new initiatives are to be sustainable they will need to include one of labour’s traditional sources of power, institutional power. These four-fold sources of power provide the basis for a strategy of union renewal in the age of globalisation.
- Full Text:
- Date Issued: 2015
- Authors: Webster, Edward
- Date: 2015
- Subjects: Globalization Labor market Labor and globalization Labor and economy Labor economics Labor supply -- Effect of automation on
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/3093 , vital:20368 , ISBN 9780868104867
- Description: In this paper I focus on building a conceptual framework for an understanding of the changing dynamics of labour and workers’ sources of power. I begin by identifying worker action that draws on traditional sources of structural and associational power. I then show how the emergence of new forms of labour action is drawing on both old and new sources of power. New global forms of worker power are examined, and I conclude by suggesting that the missing dimension in the three sources of power identified – structural, associational and societal – is institutional power. If these new initiatives are to be sustainable they will need to include one of labour’s traditional sources of power, institutional power. These four-fold sources of power provide the basis for a strategy of union renewal in the age of globalisation.
- Full Text:
- Date Issued: 2015
LRP1 is required for novobiocin-mediated fibronectin turnover:
- Boel, Natasha M-E, Hunter, Morgan C, Edkins, Adrienne L
- Authors: Boel, Natasha M-E , Hunter, Morgan C , Edkins, Adrienne L
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/164896 , vital:41182 , DOI: 10.1038/s41598-018-29531-2
- Description: Fibronectin (FN) plays a major role in the stability and organization of the extracellular matrix (ECM). We have previously demonstrated that FN interacts directly with Hsp90, as well as showing that the Hsp90 inhibitor novobiocin results in FN turnover via a receptor mediated process. However, the receptor involved has not been previously identified. LRP1 is a ubiquitous receptor responsible for the internalisation of numerous ligands that binds both Hsp90 and FN, and therefore we investigated whether LRP1 was involved in novobiocin-mediated FN turnover.
- Full Text:
- Date Issued: 2018
- Authors: Boel, Natasha M-E , Hunter, Morgan C , Edkins, Adrienne L
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/164896 , vital:41182 , DOI: 10.1038/s41598-018-29531-2
- Description: Fibronectin (FN) plays a major role in the stability and organization of the extracellular matrix (ECM). We have previously demonstrated that FN interacts directly with Hsp90, as well as showing that the Hsp90 inhibitor novobiocin results in FN turnover via a receptor mediated process. However, the receptor involved has not been previously identified. LRP1 is a ubiquitous receptor responsible for the internalisation of numerous ligands that binds both Hsp90 and FN, and therefore we investigated whether LRP1 was involved in novobiocin-mediated FN turnover.
- Full Text:
- Date Issued: 2018
Measuring the value of the arts to society: the importance of the value of externalities for lower income and education groups in South Africa
- Snowball, Jeanette D, Antrobus, Geoffrey G
- Authors: Snowball, Jeanette D , Antrobus, Geoffrey G
- Date: 2001
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143134 , vital:38204 , https://doi.org/10.1111/j.1813-6982.2001.tb00034.x
- Description: Governments in many countries have cut their support of the arts on the grounds that it is the pleasure of the higher income, well educated members of society that they are sponsoring. In the 1980's government support of the arts, even in developed countries, fell by 30 per cent (Throsby 1994). While it is true that many studies have found that arts attenders represent the educated, prosperous minority of society (Morrison and West, 1986; Dobson and West, 1990; Hendon 1990), this paper argues that if the social as well as the more traditional economic measures of the value of the arts are considered, it can be shown that many of the positive externalties provided by the arts accrue to lower income and education groups.
- Full Text:
- Date Issued: 2001
- Authors: Snowball, Jeanette D , Antrobus, Geoffrey G
- Date: 2001
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143134 , vital:38204 , https://doi.org/10.1111/j.1813-6982.2001.tb00034.x
- Description: Governments in many countries have cut their support of the arts on the grounds that it is the pleasure of the higher income, well educated members of society that they are sponsoring. In the 1980's government support of the arts, even in developed countries, fell by 30 per cent (Throsby 1994). While it is true that many studies have found that arts attenders represent the educated, prosperous minority of society (Morrison and West, 1986; Dobson and West, 1990; Hendon 1990), this paper argues that if the social as well as the more traditional economic measures of the value of the arts are considered, it can be shown that many of the positive externalties provided by the arts accrue to lower income and education groups.
- Full Text:
- Date Issued: 2001
New Unity Movement Bulletin
- Date: 1991-03
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10948/31147 , vital:31331 , Bulk File 7
- Description: The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid government.
- Full Text: false
- Date Issued: 1991-03
- Date: 1991-03
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10948/31147 , vital:31331 , Bulk File 7
- Description: The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid government.
- Full Text: false
- Date Issued: 1991-03
New Unity Movement Bulletin
- Date: 1992-11
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10948/31191 , vital:31335 , Bulk File 7
- Description: The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid government.
- Full Text: false
- Date Issued: 1992-11
- Date: 1992-11
- Subjects: Government, Resistance to -- South Africa , South Africa -- History -- 20th century , South Africa -- Politics and government
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10948/31191 , vital:31335 , Bulk File 7
- Description: The Bulletin was the official newsletter of the New Unity Movement. It was published about twice a year and contained articles reflecting the organisation's views on resistance to the Apartheid government.
- Full Text: false
- Date Issued: 1992-11
Overcoming marginalisation? Open Access research repositories at a South African and a Swedish University
- Fox, Roddy C, Wihlborg, E, Lawrence, D
- Authors: Fox, Roddy C , Wihlborg, E , Lawrence, D
- Date: 2009
- Language: English
- Type: Conference paper
- Identifier: vital:6667 , http://hdl.handle.net/10962/d1006680
- Description: Open Access Research Repositories have developed very rapidly since c2000 as a global phenomenon in their number, their location, the number and type of resources available in them. The creation of institutional repositories has been affected by different motives. They can serve as collections of a University's research output with the intention of making it 'freely' available. We ask here, just what patterns of access can be analysed, what trends do we see when examining our two institutions? Alternatively they can be seen as ways to raise the research profile of individuals and institutions and citation records. We do not see Open Access Research as being a neutral, value free technological innovation with clear outcomes. Our perspective draws from the fields of socio-technical and complex adaptive systems and so we anticipate that although the future impacts of Open Access research can be discerned they cannot be mechanistically predicted.
- Full Text:
- Date Issued: 2009
- Authors: Fox, Roddy C , Wihlborg, E , Lawrence, D
- Date: 2009
- Language: English
- Type: Conference paper
- Identifier: vital:6667 , http://hdl.handle.net/10962/d1006680
- Description: Open Access Research Repositories have developed very rapidly since c2000 as a global phenomenon in their number, their location, the number and type of resources available in them. The creation of institutional repositories has been affected by different motives. They can serve as collections of a University's research output with the intention of making it 'freely' available. We ask here, just what patterns of access can be analysed, what trends do we see when examining our two institutions? Alternatively they can be seen as ways to raise the research profile of individuals and institutions and citation records. We do not see Open Access Research as being a neutral, value free technological innovation with clear outcomes. Our perspective draws from the fields of socio-technical and complex adaptive systems and so we anticipate that although the future impacts of Open Access research can be discerned they cannot be mechanistically predicted.
- Full Text:
- Date Issued: 2009
Patriarchy, women, land and livelihoods on A1 farms in Zimbabwe
- Chiweshe, Manase K, Chakona, Loveness, Helliker, Kirk D
- Authors: Chiweshe, Manase K , Chakona, Loveness , Helliker, Kirk D
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/71204 , vital:29812 , https://doi.org/10.1177/0021909614541083
- Description: In this article, we focus on patriarchy, women, land and livelihoods on A1 farms in Zimbabwe which arose from the fast track land reform programme. There is now significant literature on A1 farms in Zimbabwe. These studies include a number of ethnographic and comparative studies but this literature does not give sustained attention to patriarchy and women. In addition, though, a small number of works have appeared based upon a more focused gender analysis. We draw upon this more focused literature and offer fresh fieldwork evidence based on recent studies undertaken by two of the authors, in Goromonzi and Mazowe districts. At times, radical socio-spatial reorganisation such as fast track may destabilise systems of patriarchy. In the case of fast track, there has been a reconfiguration of relations between men and women yet this is uneven and contradictory and remains within the confines of patriarchal structures, practices and discourses. At the same time, women have manoeuvred and negotiated at local levels to enhance their lives and livelihoods.
- Full Text: false
- Date Issued: 2015
- Authors: Chiweshe, Manase K , Chakona, Loveness , Helliker, Kirk D
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/71204 , vital:29812 , https://doi.org/10.1177/0021909614541083
- Description: In this article, we focus on patriarchy, women, land and livelihoods on A1 farms in Zimbabwe which arose from the fast track land reform programme. There is now significant literature on A1 farms in Zimbabwe. These studies include a number of ethnographic and comparative studies but this literature does not give sustained attention to patriarchy and women. In addition, though, a small number of works have appeared based upon a more focused gender analysis. We draw upon this more focused literature and offer fresh fieldwork evidence based on recent studies undertaken by two of the authors, in Goromonzi and Mazowe districts. At times, radical socio-spatial reorganisation such as fast track may destabilise systems of patriarchy. In the case of fast track, there has been a reconfiguration of relations between men and women yet this is uneven and contradictory and remains within the confines of patriarchal structures, practices and discourses. At the same time, women have manoeuvred and negotiated at local levels to enhance their lives and livelihoods.
- Full Text: false
- Date Issued: 2015
Perspectives on leadership
- Authors: Arnolds, Cecil Ashleigh
- Subjects: Leadership , Industrial management , f-sa
- Language: English
- Type: text , Lectures
- Identifier: http://hdl.handle.net/10948/21857 , vital:29794
- Description: My fields of study are business management and organizational behaviour (OB). In business management we study how to manage businesses effectively by executing various functions (marketing, finance, human resources management, general and strategic management, purchasing and logistics, public relations management, production and opertaions, information technology management) and management tasks (planning, organising, leading and control) (Bosch, Tait and Venter, 2006).
- Full Text: false
- Authors: Arnolds, Cecil Ashleigh
- Subjects: Leadership , Industrial management , f-sa
- Language: English
- Type: text , Lectures
- Identifier: http://hdl.handle.net/10948/21857 , vital:29794
- Description: My fields of study are business management and organizational behaviour (OB). In business management we study how to manage businesses effectively by executing various functions (marketing, finance, human resources management, general and strategic management, purchasing and logistics, public relations management, production and opertaions, information technology management) and management tasks (planning, organising, leading and control) (Bosch, Tait and Venter, 2006).
- Full Text: false
Physical implications of prolonged sitting in a confined posture - a literature review
- Todd, Andrew I, Bennett, Anthea I, Christie, Candice J
- Authors: Todd, Andrew I , Bennett, Anthea I , Christie, Candice J
- Date: 2007
- Language: English
- Type: Article
- Identifier: vital:6756 , http://hdl.handle.net/10962/d1009458
- Description: The main purpose of this review article was to highlight some of the physical consequences of sitting for prolonged periods in a confined setting. More specifically, the review relates this research to call centre work and where applicable comments on the limited literature relating specifically to ergonomics research within call centre settings. In particular the article explores the biomechanical stresses placed on the musculoskeletal system during prolonged sitting at a workstation, and the physiological consequences thereof. The paper then provides possible solutions to reduce the physical strain placed on these workers by looking at workstation design and work organisation emphasizing worker education and the promotion of worker well being.
- Full Text:
- Date Issued: 2007
- Authors: Todd, Andrew I , Bennett, Anthea I , Christie, Candice J
- Date: 2007
- Language: English
- Type: Article
- Identifier: vital:6756 , http://hdl.handle.net/10962/d1009458
- Description: The main purpose of this review article was to highlight some of the physical consequences of sitting for prolonged periods in a confined setting. More specifically, the review relates this research to call centre work and where applicable comments on the limited literature relating specifically to ergonomics research within call centre settings. In particular the article explores the biomechanical stresses placed on the musculoskeletal system during prolonged sitting at a workstation, and the physiological consequences thereof. The paper then provides possible solutions to reduce the physical strain placed on these workers by looking at workstation design and work organisation emphasizing worker education and the promotion of worker well being.
- Full Text:
- Date Issued: 2007
Potter's fingerprints: some prehistoric southern African utilityware in an intimate light.
- Authors: Steele, John
- Date: 2003
- Language: English
- Type: text , Article
- Identifier: http://hdl.handle.net/11260/945 , vital:30070
- Description: Extensive archaeological excavations in southern Africa during the past century have revealed a richly described heritage of widely distributed First-Millennium (C.E.) Agriculturist ceramics. In viewing both artefacts and assessments thereof it can be observed that ways of thinking shape ways of seeing, and explanations ofwhat is seen. Thus, because conceptual frameworks are inseparable from what is observed and explanations that result, consideration is given to some particular mindsets that have led to recent theories concenring local prehistoric material culture. In conclusion, a brief look at dialogues initiated by some contemporary potters who interrogate cherished lifeways and belief systems serve to elucidate current trends towards finding meaning in prehistoric southern African ceramics.
- Full Text:
- Date Issued: 2003
- Authors: Steele, John
- Date: 2003
- Language: English
- Type: text , Article
- Identifier: http://hdl.handle.net/11260/945 , vital:30070
- Description: Extensive archaeological excavations in southern Africa during the past century have revealed a richly described heritage of widely distributed First-Millennium (C.E.) Agriculturist ceramics. In viewing both artefacts and assessments thereof it can be observed that ways of thinking shape ways of seeing, and explanations ofwhat is seen. Thus, because conceptual frameworks are inseparable from what is observed and explanations that result, consideration is given to some particular mindsets that have led to recent theories concenring local prehistoric material culture. In conclusion, a brief look at dialogues initiated by some contemporary potters who interrogate cherished lifeways and belief systems serve to elucidate current trends towards finding meaning in prehistoric southern African ceramics.
- Full Text:
- Date Issued: 2003
Privilege, poverty, and pedagogy: reflections on the introduction of a service-learning component into a postgraduate political studies course
- Authors: Matthews, Sally
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142224 , vital:38060 , DOI: 10.17159/2221-4070/2017/v6i2a4
- Description: This paper reflects on the experience of integrating a service-learning component into a postgraduate course in political studies. The course in question aims to get students to reflect on the ways in which poverty and privilege are tied up with each other, and on whether and how the relatively privileged can be involved in helpful ways in struggles against oppression. The service-learning component involved spending a week volunteering with a rural community-based organisation. Students were required to relate their volunteering experience to the course content. The paper reflects on the implications of the course's failure to live up to many criteria for quality service-learning, arguing that despite its failings, the service-learning experience significantly enhanced the learning of the students and also my own learning as an educator. I show that the nature of this learning calls into question some possible assumptions about how service-learning ought to be done. The paper contributes to ongoing discussions about the ways in which service-learning can assist in the achievement of social justice-related goals.
- Full Text:
- Date Issued: 2017
- Authors: Matthews, Sally
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142224 , vital:38060 , DOI: 10.17159/2221-4070/2017/v6i2a4
- Description: This paper reflects on the experience of integrating a service-learning component into a postgraduate course in political studies. The course in question aims to get students to reflect on the ways in which poverty and privilege are tied up with each other, and on whether and how the relatively privileged can be involved in helpful ways in struggles against oppression. The service-learning component involved spending a week volunteering with a rural community-based organisation. Students were required to relate their volunteering experience to the course content. The paper reflects on the implications of the course's failure to live up to many criteria for quality service-learning, arguing that despite its failings, the service-learning experience significantly enhanced the learning of the students and also my own learning as an educator. I show that the nature of this learning calls into question some possible assumptions about how service-learning ought to be done. The paper contributes to ongoing discussions about the ways in which service-learning can assist in the achievement of social justice-related goals.
- Full Text:
- Date Issued: 2017
Probing the potential of social ecosystemic skills approaches for green skills planning: Perspectives from Expanded Public Works Programme studies
- Authors: Lotz-Sisitka, Heila
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/392924 , vital:68812 , ISBN 9780429279362 , https://doi.org/10.4324/9780429279362
- Description: The Expanded Public Works Programme (EPWP) in South Africa is an extensive governmental intervention to provide work opportunities. The EPWP context is a significant site of green skills emergence in South Africa, especially at the elementary occupation level. The training associated with these programmes has, to date, been largely top down, and little nuanced understanding exists on the training and learning pathways potential development for these green skills. There is a paradox between the top down approach to training, and the primarily regional implementation platforms of EPWP job opportunities and their developmental intent. To reconcile this paradox, I draw on social ecosystemic skills research to probe the potential for such a conceptual and theoretical framework for guiding green skills research for the EPWP. I share some methodologies and insights developed in EPWP green skills research projects that offer potential for providing insight into a social ecosystemic model for green skills research in EPWP programmes. Social ecosystemic models in skills research seek to develop skills development approaches that forge stronger connections between working, living and learning, foregrounding regional, place-based models for skills planning that require interfacing with vertical facilitatory mechanisms and horizontal connectivities.
- Full Text:
- Date Issued: 2019
- Authors: Lotz-Sisitka, Heila
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/392924 , vital:68812 , ISBN 9780429279362 , https://doi.org/10.4324/9780429279362
- Description: The Expanded Public Works Programme (EPWP) in South Africa is an extensive governmental intervention to provide work opportunities. The EPWP context is a significant site of green skills emergence in South Africa, especially at the elementary occupation level. The training associated with these programmes has, to date, been largely top down, and little nuanced understanding exists on the training and learning pathways potential development for these green skills. There is a paradox between the top down approach to training, and the primarily regional implementation platforms of EPWP job opportunities and their developmental intent. To reconcile this paradox, I draw on social ecosystemic skills research to probe the potential for such a conceptual and theoretical framework for guiding green skills research for the EPWP. I share some methodologies and insights developed in EPWP green skills research projects that offer potential for providing insight into a social ecosystemic model for green skills research in EPWP programmes. Social ecosystemic models in skills research seek to develop skills development approaches that forge stronger connections between working, living and learning, foregrounding regional, place-based models for skills planning that require interfacing with vertical facilitatory mechanisms and horizontal connectivities.
- Full Text:
- Date Issued: 2019
Quinones and halogenated monoterpenes of algal origin show anti-proliferative effects against breast cancer cells in vitro:
- de la Mare, Jo-Anne, Lawson, Jessica C, Chiwakata, Maynard T, Beukes, Denzil R, Blatch, Gregory L, Edkins, Adrienne L
- Authors: de la Mare, Jo-Anne , Lawson, Jessica C , Chiwakata, Maynard T , Beukes, Denzil R , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2012
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165165 , vital:41214 , DOI: 10.1007/s10637-011-9788-0
- Description: Red and brown algae have been shown to produce a variety of compounds with chemotherapeutic potential. A recent report described the isolation of a range of novel polyhalogenated monoterpene compounds from the red algae Plocamium corallorhiza and Plocamium cornutum collected off the coast of South Africa, together with the previously described tetraprenylquinone, sargaquinoic acid (SQA), from the brown algae Sargassum heterophyllum. In our study, the algal compounds were screened for anti-proliferative activity against metastatic MDA-MB-231 breast cancer cells revealing that a number of compounds displayed anti-cancer activity with IC50 values in the micromolar range. A subset of the compounds was tested for differential toxicity in the MCF-7/MCF12A system and five of these, including sargaquinoic acid, were found to be at least three times more toxic to the breast cancer than the non-malignant cell line.
- Full Text:
- Date Issued: 2012
- Authors: de la Mare, Jo-Anne , Lawson, Jessica C , Chiwakata, Maynard T , Beukes, Denzil R , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2012
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165165 , vital:41214 , DOI: 10.1007/s10637-011-9788-0
- Description: Red and brown algae have been shown to produce a variety of compounds with chemotherapeutic potential. A recent report described the isolation of a range of novel polyhalogenated monoterpene compounds from the red algae Plocamium corallorhiza and Plocamium cornutum collected off the coast of South Africa, together with the previously described tetraprenylquinone, sargaquinoic acid (SQA), from the brown algae Sargassum heterophyllum. In our study, the algal compounds were screened for anti-proliferative activity against metastatic MDA-MB-231 breast cancer cells revealing that a number of compounds displayed anti-cancer activity with IC50 values in the micromolar range. A subset of the compounds was tested for differential toxicity in the MCF-7/MCF12A system and five of these, including sargaquinoic acid, were found to be at least three times more toxic to the breast cancer than the non-malignant cell line.
- Full Text:
- Date Issued: 2012
Refocusing the traumatic past (an essay in two parts):
- Authors: de Jager, Maureen
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147380 , vital:38631 , https://0-hdl.handle.net.wam.seals.ac.za/10520/EJC-a867f5bb0
- Description: In the greater landscape of South Africa’s traumatic past, the South African War of 1899-1902 is arguably “old history”, surpassed in time and importance by more pressing traumas. Moreover, because it was usurped by Afrikaner nationalism as a myth of national origin and used to justify claims of Afrikaner sovereignty, it is also often seen as “old Afrikaner history”: at best, an episode of limited relevance to the many South Africans effectively written out of this narrative; at worst, a platform for nostalgic hankering by a conservative few.
- Full Text:
- Date Issued: 2017
- Authors: de Jager, Maureen
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147380 , vital:38631 , https://0-hdl.handle.net.wam.seals.ac.za/10520/EJC-a867f5bb0
- Description: In the greater landscape of South Africa’s traumatic past, the South African War of 1899-1902 is arguably “old history”, surpassed in time and importance by more pressing traumas. Moreover, because it was usurped by Afrikaner nationalism as a myth of national origin and used to justify claims of Afrikaner sovereignty, it is also often seen as “old Afrikaner history”: at best, an episode of limited relevance to the many South Africans effectively written out of this narrative; at worst, a platform for nostalgic hankering by a conservative few.
- Full Text:
- Date Issued: 2017
Rewrite, revise, refine, reflect, rethink: the long and short of teaching journalism at Rhodes
- Authors: Garman, Anthea
- Date: 2012
- Language: English
- Type: Text
- Identifier: vital:585 , http://hdl.handle.net/10962/d1018945 , https://orcid.org/0000-0002-8715-8542
- Description: Vice-Chancellor’s 2011 Senior Distinguished Teaching Award lecture, 10 October 2012
- Full Text:
- Date Issued: 2012
- Authors: Garman, Anthea
- Date: 2012
- Language: English
- Type: Text
- Identifier: vital:585 , http://hdl.handle.net/10962/d1018945 , https://orcid.org/0000-0002-8715-8542
- Description: Vice-Chancellor’s 2011 Senior Distinguished Teaching Award lecture, 10 October 2012
- Full Text:
- Date Issued: 2012
Reflections on Teaching Africa in South Africa:
- Authors: Matthews, Sally
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142235 , vital:38061 , DOI: 10.1111/1467-9256.12107
- Description: This article draws on the author’s experience of teaching African Studies to undergraduate South African students in order to reflect on some of the key challenges facing teachers of African Studies, both in South Africa and beyond. In particular, it discusses challenges relating to teaching a field as contested as African Studies, looking at whether teaching African alternatives to mainstream African politics is helpful and at whether and how one can teach Africa in a way that encourages and develops critical thinking. The article also explores how the racial politics of the context in which one teaches African Studies inevitably affects the way in which students engage with the content of the course. While the article discusses these issues in relation to the South African higher education context in particular, implications for other contexts are also highlighted.
- Full Text:
- Date Issued: 2016
- Authors: Matthews, Sally
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142235 , vital:38061 , DOI: 10.1111/1467-9256.12107
- Description: This article draws on the author’s experience of teaching African Studies to undergraduate South African students in order to reflect on some of the key challenges facing teachers of African Studies, both in South Africa and beyond. In particular, it discusses challenges relating to teaching a field as contested as African Studies, looking at whether teaching African alternatives to mainstream African politics is helpful and at whether and how one can teach Africa in a way that encourages and develops critical thinking. The article also explores how the racial politics of the context in which one teaches African Studies inevitably affects the way in which students engage with the content of the course. While the article discusses these issues in relation to the South African higher education context in particular, implications for other contexts are also highlighted.
- Full Text:
- Date Issued: 2016