https://vital.seals.ac.za/vital/access/manager/Index en-us 5 https://vital.seals.ac.za/vital/access/manager/Repository/vital:26461 5% per liver weight in all treated groups. The present study demonstrates that these two plant extracts and metformin have different glucogenic and lipogenic effects from that presented by HFD alone when compared to the LFD alone. In conclusion, metformin and P. africana extract can attenuate HFD‐induced fatty liver without changing the dietary habits. Hence S. frutescens extract is less effective in the prevention of HFD‐induced fatty liver. A change in the dietary habits is recommended to be considered during the use of these three remedies in the treatment of HFD‐induced insulin resistance and fatty liver. All three treatments enhanced antioxidant capacity, and may improve insulin resistance and fatty liver mediated by the present HFD through different mechanism of actions in the liver.]]> Wed 12 May 2021 19:40:44 SAST ]]> https://vital.seals.ac.za/vital/access/manager/Repository/vital:10330 Thu 13 May 2021 08:17:59 SAST ]]>