https://vital.seals.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 https://vital.seals.ac.za/vital/access/manager/Repository/vital:4141 Wed 12 May 2021 23:28:19 SAST ]]> https://vital.seals.ac.za/vital/access/manager/Repository/vital:3985 Wed 12 May 2021 22:57:14 SAST ]]> https://vital.seals.ac.za/vital/access/manager/Repository/vital:4130 Wed 12 May 2021 18:19:45 SAST ]]> https://vital.seals.ac.za/vital/access/manager/Repository/vital:10338 Thu 13 May 2021 07:01:58 SAST ]]> https://vital.seals.ac.za/vital/access/manager/Repository/vital:10316 125 μg/ml. These results suggest that the extract may be selective for specific cell types. Bio-assay guided fractionation of the S. ellipticum ethanolic extract yielded two active fractions; chloroform and ethyl acetate. Two compounds isolated from the chloroform extract were screened against the three cancer cell lines and found to be inactive. Three compounds were isolated from the ethyl acetate fraction and revealed IC50 values < 62.5 and < 31 μg/ml against MCF-7. Unfortunately these two compounds soon lost activity before any further work could be done on them and work was continued with the crude extract.]]> Thu 13 May 2021 05:53:54 SAST ]]>