https://vital.seals.ac.za/vital/access/manager/Index en-us 5 Synthesis, photophysicochemical properties and photodynamic therapy activities of indium and zinc phthalocyanines when incorporated into Pluronic polymer micelles https://vital.seals.ac.za/vital/access/manager/Repository/vital:41489 50% cell viability) at concentrations ≤100 μg/mL, however the conjugates showed < 45% cell viability at concentrations ≤ 100 μg/mL, probably due to the small micellar size and EPR effect. The findings from this work show the importance of incorporating photosensitizers such as phthalocyanines into Pluronic polymers micelles and making them water soluble and ultimately improving their photodynamic effect.]]> Wed 12 May 2021 14:58:28 SAST ]]> Physicochemical properties and photodynamic therapy activities of indium and zinc phthalocyanine-nanoparticle conjugates https://vital.seals.ac.za/vital/access/manager/Repository/vital:30589 50Îll viability at concentrations≤ 160μg/mL, however the conjugates showed<50% cell viabilityatconcentrations≤ 160μg/mLprobably due to the enhanced singlet oxygen quantum yield. The findings from this work show the importance of linking photosensitises such as phthalocyanines to metal nanoparticles for the enhancement ofsinglet oxygen quantum yield and ultimately the photodynamic effect.]]> Thu 13 May 2021 08:10:17 SAST ]]>